Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4tpr_L.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 3.A N SER 26.A OG no hydrogen 2.879 N/A THR 5.A N ARG 24.A O no hydrogen 2.872 N/A GLN 6.A NE2.A TYR 91.A O no hydrogen 2.918 N/A GLN 6.A NE2.A THR 107.A OG1 no hydrogen 3.035 N/A GLN 6.A NE2.B TYR 91.A O no hydrogen 2.667 N/A THR 7.A N SER 22.A O no hydrogen 2.995 N/A SER 10.A OG.C GLU 110.A OE2 no hydrogen 2.646 N/A LEU 11.A N LYS 108.A O no hydrogen 2.763 N/A VAL 13.A N GLU 110.A O no hydrogen 2.838 N/A SER 14.A N ASP 17.A OD2 no hydrogen 2.842 N/A GLY 16.A N VAL 83.A O no hydrogen 2.840 N/A ASP 17.A N SER 14.A O no hydrogen 3.032 N/A ALA 19.A N ILE 80.A O no hydrogen 2.934 N/A ILE 21.A N LEU 78.A O no hydrogen 2.881 N/A SER 22.A N THR 7.A O no hydrogen 2.865 N/A CYS 23.A N.A PHE 76.A O no hydrogen 2.834 N/A CYS 23.A N.B PHE 76.A O no hydrogen 2.851 N/A CYS 23.A SG.A THR 5.A O no hydrogen 4.023 N/A CYS 23.A SG.A SER 22.A O no hydrogen 3.334 N/A ARG 24.A N THR 5.A O no hydrogen 2.859 N/A ARG 24.A NE ASP 75.A OD1.A no hydrogen 2.796 N/A ARG 24.A NE ASP 75.A OD1.B no hydrogen 2.603 N/A ARG 24.A NH2 ASP 75.A OD1.B no hydrogen 3.090 N/A ARG 24.A NH2 ASP 75.A OD2.A no hydrogen 2.687 N/A ARG 24.A NH2 ASP 75.A OD2.B no hydrogen 3.211 N/A SER 25.A N THR 74.A O no hydrogen 2.892 N/A SER 25.A OG GLN 27.A O no hydrogen 2.707 N/A SER 25.A OG THR 74.A O no hydrogen 3.484 N/A SER 26.A N LEU 3.A O no hydrogen 2.904 N/A SER 26.A OG LEU 3.A O no hydrogen 3.548 N/A ILE 29.A N GLY 73.A O no hydrogen 3.303 N/A VAL 30.A N SER 28.A OG.A no hydrogen 3.282 N/A HIS 31.A N ASN 35.A O no hydrogen 2.787 N/A ASN 33.A N HIS 31.A ND1 no hydrogen 2.990 N/A ASN 33.A ND2 TYR 37.A OH no hydrogen 2.936 N/A GLY 34.A N HIS 31.A O no hydrogen 2.881 N/A ASN 35.A N ASN 33.A OD1 no hydrogen 2.867 N/A ASN 35.A ND2 ASN 33.A OD1 no hydrogen 3.253 N/A ASN 35.A ND2 TYR 37.A OH no hydrogen 2.983 N/A TYR 37.A N SER 97.A OG no hydrogen 3.155 N/A LEU 38.A N THR 36.A O no hydrogen 2.956 N/A GLU 39.A N PHE 94.A O no hydrogen 2.811 N/A TRP 40.A N ILE 53.A O no hydrogen 3.009 N/A TYR 41.A N TYR 92.A O no hydrogen 2.817 N/A TYR 41.A OH GLU 39.A OE1 no hydrogen 2.593 N/A LEU 42.A N LYS 50.A O no hydrogen 2.972 N/A GLN 43.A N VAL 90.A O no hydrogen 2.766 N/A GLN 43.A NE2 GLN 47.A O no hydrogen 2.949 N/A LYS 44.A NZ GLU 86.A O no hydrogen 2.767 N/A LYS 44.A NZ LEU 88.A O no hydrogen 2.762 N/A GLN 47.A N LYS 44.A O no hydrogen 3.089 N/A LYS 50.A N LEU 42.A O no hydrogen 2.824 N/A LEU 52.A N TRP 40.A O no hydrogen 2.813 N/A ILE 53.A N TRP 40.A O no hydrogen 3.388 N/A TYR 54.A N ASN 58.A O no hydrogen 2.880 N/A LYS 55.A NZ ASN 35.A OD1 no hydrogen 2.913 N/A VAL 56.A N LEU 38.A O no hydrogen 2.863 N/A SER 57.A N LYS 55.A O no hydrogen 2.816 N/A ASN 58.A N TYR 54.A O no hydrogen 2.955 N/A ASN 58.A ND2 TYR 54.A O no hydrogen 3.437 N/A ASN 58.A ND2 LYS 55.A O no hydrogen 3.196 N/A ARG 59.A NH1 VAL 63.A O no hydrogen 2.883 N/A PHE 60.A N LEU 52.A O no hydrogen 2.952 N/A VAL 63.A N PHE 60.A O no hydrogen 3.088 N/A ARG 66.A NE ASP 87.A OD1 no hydrogen 3.371 N/A ARG 66.A NE ASP 87.A OD2 no hydrogen 2.777 N/A ARG 66.A NH2 GLU 86.A OE2 no hydrogen 2.916 N/A ARG 66.A NH2 ASP 87.A OD1 no hydrogen 2.729 N/A ARG 66.A NH2 ASP 87.A OD2 no hydrogen 3.544 N/A PHE 67.A N PRO 64.A O no hydrogen 3.219 N/A SER 68.A N LYS 79.A O no hydrogen 2.938 N/A SER 70.A N THR 77.A O no hydrogen 2.979 N/A SER 72.A N ASP 75.A O no hydrogen 2.872 N/A SER 72.A OG ASP 75.A O no hydrogen 3.351 N/A THR 74.A N SER 72.A OG no hydrogen 3.258 N/A THR 74.A OG1 ASP 75.A OD1.A no hydrogen 3.146 N/A ASP 75.A N SER 72.A OG no hydrogen 2.990 N/A PHE 76.A N CYS 23.A O.A no hydrogen 2.828 N/A PHE 76.A N CYS 23.A O.B no hydrogen 2.832 N/A THR 77.A N SER 70.A O no hydrogen 2.900 N/A LEU 78.A N ILE 21.A O no hydrogen 2.782 N/A LYS 79.A N SER 68.A O no hydrogen 2.829 N/A ILE 80.A N ALA 19.A O no hydrogen 2.825 N/A SER 81.A N ARG 66.A O no hydrogen 2.925 N/A VAL 83.A N ASP 17.A O no hydrogen 2.846 N/A GLU 84.A N ASP 87.A OD2 no hydrogen 2.854 N/A ASP 87.A N GLU 84.A O no hydrogen 2.888 N/A LEU 88.A N ALA 85.A O no hydrogen 3.472 N/A GLY 89.A N LEU 109.A O no hydrogen 3.173 N/A VAL 90.A N GLN 43.A O no hydrogen 2.990 N/A TYR 91.A N THR 107.A O no hydrogen 2.872 N/A TYR 91.A OH ASP 87.A O no hydrogen 2.612 N/A TYR 92.A N TYR 41.A O no hydrogen 2.912 N/A CYS 93.A N GLN 6.A OE1.A no hydrogen 3.064 N/A CYS 93.A N GLN 6.A OE1.B no hydrogen 3.288 N/A CYS 93.A SG GLN 6.A OE1.B no hydrogen 3.660 N/A GLN 95.A N THR 102.A O no hydrogen 2.932 N/A GLN 95.A NE2 HIS 98.A O no hydrogen 3.033 N/A GLN 95.A NE2 THR 102.A OG1 no hydrogen 3.070 N/A GLY 96.A N TYR 37.A O no hydrogen 2.897 N/A SER 97.A N GLN 95.A OE1 no hydrogen 2.770 N/A SER 97.A OG ILE 29.A O no hydrogen 2.575 N/A HIS 98.A N GLN 95.A OE1 no hydrogen 2.948 N/A THR 102.A N GLN 95.A O no hydrogen 3.196 N/A THR 102.A OG1 VAL 2.A O no hydrogen 2.708 N/A GLY 104.A N CYS 93.A O no hydrogen 2.888 N/A GLY 106.A N GLN 6.A OE1.A no hydrogen 3.093 N/A GLY 106.A N GLN 6.A OE1.B no hydrogen 3.237 N/A THR 107.A N TYR 91.A O no hydrogen 2.852 N/A THR 107.A OG1 PRO 8.A O no hydrogen 2.634 N/A LYS 108.A N LEU 9.A O no hydrogen 2.927 N/A LYS 108.A NZ ASP 170.A OD1 no hydrogen 2.574 N/A LYS 108.A NZ ASP 170.A OD2 no hydrogen 3.529 N/A LEU 109.A N GLY 89.A O no hydrogen 2.812 N/A GLU 110.A N LEU 11.A O no hydrogen 3.178 N/A ILE 111.A N GLN 171.A OE1 no hydrogen 2.983 N/A LYS 112.A N VAL 13.A O no hydrogen 2.819 N/A ARG 113.A NE ALA 114.A O no hydrogen 2.793 N/A ARG 113.A NH1 ASP 175.A O no hydrogen 2.798 N/A ARG 113.A NH2 ALA 114.A O no hydrogen 3.509 N/A ALA 116.A N TYR 145.A O no hydrogen 2.807 N/A THR 119.A N ASN 142.A O no hydrogen 2.853 N/A THR 119.A OG1 ASN 142.A O no hydrogen 3.505 N/A SER 121.A N PHE 140.A O no hydrogen 2.968 N/A PHE 123.A N VAL 138.A O no hydrogen 2.795 N/A SER 127.A OG GLU 128.A OE1 no hydrogen 3.499 N/A GLU 128.A N GLU 128.A OE1 no hydrogen 2.834 N/A GLN 129.A N SER 126.A OG no hydrogen 3.154 N/A GLN 129.A NE2 SER 136.A OG no hydrogen 2.780 N/A LEU 130.A N SER 126.A O no hydrogen 3.053 N/A THR 131.A N SER 127.A O no hydrogen 2.937 N/A THR 131.A OG1 SER 127.A O no hydrogen 3.062 N/A SER 132.A N GLN 129.A O no hydrogen 2.847 N/A SER 132.A OG GLU 128.A O no hydrogen 3.365 N/A GLY 133.A N LEU 130.A O no hydrogen 2.948 N/A GLY 134.A N GLN 129.A O no hydrogen 3.236 N/A ALA 135.A N LEU 186.A O no hydrogen 3.008 N/A SER 136.A N GLN 129.A OE1 no hydrogen 2.799 N/A SER 136.A OG THR 185.A OG1 no hydrogen 2.921 N/A VAL 137.A N LEU 184.A O no hydrogen 2.785 N/A VAL 138.A N PHE 123.A O no hydrogen 3.096 N/A CYS 139.A N.A SER 182.A O no hydrogen 2.815 N/A CYS 139.A N.B SER 182.A O no hydrogen 2.806 N/A CYS 139.A SG.A SER 121.A O no hydrogen 3.903 N/A CYS 139.A SG.B SER 121.A O no hydrogen 3.836 N/A CYS 139.A SG.B VAL 138.A O no hydrogen 3.720 N/A PHE 140.A N SER 121.A O no hydrogen 2.864 N/A LEU 141.A N MET 180.A O no hydrogen 2.851 N/A ASN 142.A N THR 119.A O no hydrogen 2.909 N/A ASN 143.A N SER 179.A OG no hydrogen 2.928 N/A ASN 143.A ND2 ASP 175.A OD2 no hydrogen 2.952 N/A ASN 143.A ND2 THR 177.A OG1 no hydrogen 3.357 N/A PHE 144.A N TYR 178.A O no hydrogen 2.842 N/A TYR 145.A N ALA 116.A O no hydrogen 2.901 N/A TYR 145.A OH ILE 111.A O no hydrogen 3.313 N/A LYS 147.A NZ SER 10.A OG.B no hydrogen 2.709 N/A LYS 147.A NZ SER 10.A OG.C no hydrogen 2.789 N/A LYS 147.A NZ GLU 110.A OE2 no hydrogen 2.712 N/A ASN 150.A N.A THR 202.A O no hydrogen 3.160 N/A ASN 150.A N.B THR 202.A O no hydrogen 3.140 N/A LYS 152.A N GLU 200.A O no hydrogen 2.801 N/A LYS 152.A NZ GLU 159.A OE1.B no hydrogen 2.902 N/A LYS 152.A NZ GLU 159.A OE2.A no hydrogen 3.446 N/A LYS 152.A NZ GLU 159.A OE2.B no hydrogen 3.231 N/A TRP 153.A NE1 SER 182.A OG no hydrogen 2.907 N/A LYS 154.A N THR 198.A O no hydrogen 2.819 N/A ILE 155.A N SER 158.A O no hydrogen 2.844 N/A ASP 156.A N SER 196.A O no hydrogen 2.837 N/A SER 158.A N ILE 155.A O no hydrogen 2.955 N/A ARG 160.A N TRP 153.A O no hydrogen 2.958 N/A ARG 160.A NE ASN 162.A O no hydrogen 2.953 N/A ARG 160.A NH1 GLU 190.A OE2 no hydrogen 2.756 N/A ARG 160.A NH2 GLU 190.A OE1 no hydrogen 2.954 N/A GLN 161.A NE2 GLU 159.A OE2.A no hydrogen 2.728 N/A GLN 161.A NE2 GLU 159.A OE2.B no hydrogen 2.964 N/A VAL 164.A N GLN 161.A O no hydrogen 3.287 N/A LEU 165.A N THR 183.A O no hydrogen 2.787 N/A SER 167.A N SER 181.A O no hydrogen 2.884 N/A THR 169.A N SER 179.A O no hydrogen 2.971 N/A THR 169.A OG1 SER 179.A O no hydrogen 3.469 N/A GLN 171.A N ASP 170.A OD1 no hydrogen 2.758 N/A GLN 171.A NE2 ILE 111.A O no hydrogen 2.815 N/A GLN 171.A NE2 SER 176.A O no hydrogen 2.950 N/A ASP 172.A N THR 177.A O no hydrogen 2.813 N/A LYS 174.A N ASP 172.A OD2 no hydrogen 2.939 N/A ASP 175.A N ASP 172.A OD2 no hydrogen 2.967 N/A SER 176.A N ASP 172.A O no hydrogen 2.911 N/A THR 177.A N ASP 175.A OD1 no hydrogen 2.935 N/A THR 177.A OG1 ASP 175.A OD1 no hydrogen 2.688 N/A THR 177.A OG1 ASP 175.A OD2 no hydrogen 3.388 N/A TYR 178.A N PHE 144.A O no hydrogen 2.835 N/A TYR 178.A OH GLU 110.A OE1 no hydrogen 2.807 N/A MET 180.A N LEU 141.A O no hydrogen 2.840 N/A SER 181.A N SER 167.A O no hydrogen 2.825 N/A SER 182.A N CYS 139.A O.A no hydrogen 2.883 N/A SER 182.A N CYS 139.A O.B no hydrogen 2.832 N/A SER 182.A OG ASN 166.A OD1 no hydrogen 2.586 N/A THR 183.A N LEU 165.A O no hydrogen 2.872 N/A LEU 184.A N VAL 137.A O no hydrogen 2.814 N/A THR 185.A N GLY 163.A O no hydrogen 2.824 N/A THR 185.A OG1 SER 136.A OG no hydrogen 2.921 N/A LEU 186.A N ALA 135.A O no hydrogen 2.897 N/A LYS 188.A N GLY 133.A O no hydrogen 3.074 N/A LYS 188.A NZ GLU 192.A OE1 no hydrogen 3.262 N/A LYS 188.A NZ GLU 192.A OE2 no hydrogen 2.813 N/A GLU 190.A N THR 187.A OG1 no hydrogen 2.989 N/A TYR 191.A N THR 187.A O no hydrogen 2.928 N/A GLU 192.A N LYS 188.A O no hydrogen 3.010 N/A ARG 193.A N.A GLU 190.A O no hydrogen 2.986 N/A ARG 193.A N.B GLU 190.A O no hydrogen 2.972 N/A ARG 193.A NH2.A ASP 189.A OD2 no hydrogen 2.595 N/A HIS 194.A N TYR 191.A O no hydrogen 3.398 N/A ASN 195.A N ASP 156.A OD1 no hydrogen 3.187 N/A ASN 195.A N ASP 156.A OD2 no hydrogen 3.085 N/A SER 196.A N ASP 156.A OD1 no hydrogen 2.775 N/A SER 196.A OG SER 213.A OG no hydrogen 3.429 N/A TYR 197.A N PHE 214.A O no hydrogen 2.908 N/A TYR 197.A OH TYR 191.A O no hydrogen 2.696 N/A THR 198.A N LYS 154.A O no hydrogen 2.858 N/A THR 198.A OG1 SER 213.A OG no hydrogen 2.773 N/A CYS 199.A N LYS 212.A O no hydrogen 2.921 N/A CYS 199.A SG.B LYS 212.A O no hydrogen 4.042 N/A GLU 200.A N LYS 152.A O no hydrogen 2.759 N/A ALA 201.A N ILE 210.A O no hydrogen 2.728 N/A THR 202.A N ASN 150.A O.A no hydrogen 2.838 N/A THR 202.A N ASN 150.A O.B no hydrogen 2.926 N/A THR 202.A OG1 ASN 150.A O.A no hydrogen 3.447 N/A HIS 203.A ND1 THR 205.A OG1 no hydrogen 2.843 N/A HIS 203.A NE2 PRO 146.A O no hydrogen 2.851 N/A LYS 204.A NZ ASP 115.A OD1 no hydrogen 3.156 N/A LYS 204.A NZ ASP 115.A OD2 no hydrogen 2.523 N/A THR 205.A N HIS 203.A ND1 no hydrogen 3.305 N/A THR 205.A OG1 HIS 203.A ND1 no hydrogen 2.843 N/A SER 206.A N HIS 203.A O no hydrogen 3.130 N/A SER 206.A OG SER 208.A O no hydrogen 2.805 N/A ILE 210.A N ALA 201.A O no hydrogen 2.684 N/A LYS 212.A N CYS 199.A O no hydrogen 3.020 N/A LYS 212.A NZ VAL 120.A O no hydrogen 2.699 N/A SER 213.A OG TYR 197.A O no hydrogen 3.019 N/A SER 213.A OG THR 198.A OG1 no hydrogen 2.773 N/A PHE 214.A N TYR 197.A O no hydrogen 3.015 N/A ARG 216.A N ASN 195.A O no hydrogen 2.759 N/A ARG 216.A NE TYR 191.A O no hydrogen 3.397 N/A ARG 216.A NE HIS 194.A O no hydrogen 2.822 N/A ARG 216.A NH2 HIS 194.A O no hydrogen 3.053 N/A GLU 218.A N ASN 215.A O no hydrogen 2.964 N/A