Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4tr8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): SER 15.A OG GLU 80.A O no hydrogen 2.934 N/A MET 17.A N SER 15.A OG no hydrogen 3.281 N/A HIS 18.A N GLU 77.A O no hydrogen 3.095 N/A HIS 18.A NE2 ASP 102.A OD2 no hydrogen 2.803 N/A PHE 19.A N ILE 103.A O no hydrogen 2.939 N/A THR 20.A OG1 ASP 74.A OD2 no hydrogen 2.741 N/A ILE 21.A N ILE 101.A O no hydrogen 2.930 N/A GLN 22.A NE2 ASP 98.A O no hydrogen 2.799 N/A ARG 23.A N VAL 99.A O no hydrogen 2.845 N/A ARG 23.A NE CYS 92.A O no hydrogen 3.167 N/A ARG 23.A NE LYS 93.A O no hydrogen 3.378 N/A ARG 23.A NE LEU 95.A O no hydrogen 2.981 N/A ARG 23.A NH1 GLU 24.A OE2 no hydrogen 2.927 N/A ARG 23.A NH2 LYS 93.A O no hydrogen 2.692 N/A LEU 26.A N GLN 22.A O no hydrogen 3.114 N/A LEU 27.A N ARG 23.A O no hydrogen 2.901 N/A LYS 28.A N GLU 24.A O no hydrogen 3.288 N/A LEU 30.A N LEU 26.A O no hydrogen 3.167 N/A GLN 31.A N LEU 27.A O no hydrogen 2.889 N/A VAL 33.A N PRO 29.A O no hydrogen 2.868 N/A ALA 34.A N LEU 30.A O no hydrogen 2.798 N/A GLY 35.A N GLN 31.A O no hydrogen 3.100 N/A GLY 35.A N LEU 32.A O no hydrogen 3.223 N/A VAL 36.A N VAL 33.A O no hydrogen 3.291 N/A VAL 37.A N ALA 34.A O no hydrogen 3.108 N/A LEU 43.A N LEU 40.A O no hydrogen 3.102 N/A SER 44.A N PRO 41.A O no hydrogen 3.120 N/A SER 44.A OG GLU 38.A O no hydrogen 3.448 N/A ASN 45.A N VAL 42.A O no hydrogen 3.004 N/A ASN 45.A ND2 THR 82.A OG1 no hydrogen 3.023 N/A VAL 46.A N VAL 83.A O no hydrogen 2.846 N/A LEU 47.A N THR 58.A O no hydrogen 2.868 N/A LEU 48.A N ILE 81.A O no hydrogen 2.754 N/A VAL 49.A N SER 56.A O no hydrogen 2.942 N/A VAL 50.A N GLY 79.A O no hydrogen 2.798 N/A GLU 51.A N GLN 54.A O no hydrogen 3.013 N/A GLN 54.A N GLU 51.A O no hydrogen 2.926 N/A LEU 55.A N VAL 70.A O no hydrogen 2.896 N/A SER 56.A N VAL 49.A O no hydrogen 2.896 N/A LEU 57.A N GLY 68.A O no hydrogen 2.860 N/A THR 58.A N LEU 47.A O no hydrogen 2.901 N/A GLY 59.A N LEU 66.A O no hydrogen 2.954 N/A THR 60.A OG1 VAL 64.A O no hydrogen 2.814 N/A ASP 61.A N VAL 64.A O no hydrogen 3.319 N/A LEU 62.A N THR 60.A OG1 no hydrogen 3.057 N/A GLU 63.A N ASP 61.A OD1 no hydrogen 2.908 N/A VAL 64.A N ASP 61.A OD1 no hydrogen 2.802 N/A GLU 65.A N THR 247.A O no hydrogen 2.759 N/A LEU 66.A N GLY 59.A O no hydrogen 2.896 N/A VAL 67.A N THR 245.A O no hydrogen 2.819 N/A GLY 68.A N LEU 57.A O no hydrogen 2.772 N/A ARG 69.A N GLU 243.A O no hydrogen 2.863 N/A ARG 69.A NE GLY 242.A O no hydrogen 2.956 N/A ARG 69.A NH1 THR 245.A OG1 no hydrogen 2.887 N/A ARG 69.A NH2 THR 245.A OG1 no hydrogen 2.775 N/A VAL 70.A N LEU 55.A O no hydrogen 2.898 N/A LEU 72.A N GLN 53.A O no hydrogen 2.673 N/A GLU 77.A N HIS 18.A O no hydrogen 2.776 N/A GLY 79.A N VAL 50.A O no hydrogen 3.173 N/A ILE 81.A N LEU 48.A O no hydrogen 2.997 N/A THR 82.A N LEU 124.A O no hydrogen 2.961 N/A THR 82.A OG1 LEU 124.A O no hydrogen 2.808 N/A VAL 83.A N VAL 46.A O no hydrogen 3.123 N/A ALA 85.A N SER 44.A O no hydrogen 2.979 N/A ARG 86.A NE ASP 90.A OD2 no hydrogen 3.187 N/A LEU 88.A N PRO 84.A O no hydrogen 3.104 N/A MET 89.A N ALA 85.A O no hydrogen 2.929 N/A ASP 90.A N ARG 86.A O no hydrogen 2.781 N/A ILE 91.A N LYS 87.A O no hydrogen 2.930 N/A CYS 92.A N LEU 88.A O no hydrogen 2.985 N/A CYS 92.A SG.A ARG 23.A O no hydrogen 3.465 N/A CYS 92.A SG.B LEU 88.A O no hydrogen 3.301 N/A LYS 93.A N MET 89.A O no hydrogen 2.858 N/A SER 94.A N ASP 90.A O no hydrogen 3.044 N/A SER 94.A OG ASP 90.A O no hydrogen 3.261 N/A SER 94.A OG ILE 91.A O no hydrogen 2.576 N/A LEU 95.A N ILE 91.A O no hydrogen 3.122 N/A LEU 95.A N CYS 92.A O no hydrogen 3.228 N/A ASP 98.A N GLU 24.A OE1 no hydrogen 3.222 N/A ASP 98.A N GLU 24.A OE2 no hydrogen 2.912 N/A VAL 99.A N PRO 96.A O no hydrogen 3.304 N/A ILE 101.A N ILE 21.A O no hydrogen 2.713 N/A ASP 102.A N LYS 113.A O no hydrogen 2.688 N/A ILE 103.A N PHE 19.A O no hydrogen 2.849 N/A ARG 104.A N LEU 111.A O no hydrogen 2.953 N/A ARG 104.A NE ASP 102.A OD1 no hydrogen 2.985 N/A ARG 104.A NH2 ASP 102.A OD1 no hydrogen 2.915 N/A ARG 104.A NH2 ASP 102.A OD2 no hydrogen 3.226 N/A VAL 105.A N MET 17.A O no hydrogen 2.923 N/A GLU 106.A N LYS 109.A O no hydrogen 3.005 N/A LYS 109.A N GLU 106.A O no hydrogen 3.103 N/A LEU 110.A N LEU 121.A O no hydrogen 2.841 N/A LEU 111.A N ARG 104.A O no hydrogen 2.782 N/A VAL 112.A N PHE 119.A O no hydrogen 2.873 N/A LYS 113.A N ASP 102.A O no hydrogen 2.842 N/A ALA 114.A N SER 117.A O no hydrogen 3.148 N/A SER 117.A N ALA 114.A O no hydrogen 2.941 N/A SER 117.A OG ALA 114.A O no hydrogen 3.399 N/A PHE 119.A N VAL 112.A O no hydrogen 2.779 N/A LEU 121.A N LEU 110.A O no hydrogen 2.913 N/A THR 123.A OG1 GLN 108.A O no hydrogen 2.699 N/A LEU 124.A N THR 82.A O no hydrogen 3.044 N/A ASP 128.A N PRO 125.A O no hydrogen 3.033 N/A PHE 129.A N ALA 126.A O no hydrogen 2.935 N/A LEU 139.A N LEU 232.A O no hydrogen 3.183 N/A PHE 141.A N ILE 230.A O no hydrogen 3.015 N/A ILE 143.A N VAL 228.A O no hydrogen 2.929 N/A GLN 145.A N GLY 226.A O no hydrogen 2.809 N/A GLN 145.A NE2 GLU 227.A O no hydrogen 2.965 N/A LEU 148.A N ALA 144.A O no hydrogen 3.157 N/A ARG 149.A N GLN 145.A O no hydrogen 2.840 N/A ARG 149.A NE ASP 153.A OD2 no hydrogen 2.975 N/A ARG 150.A N SER 146.A O no hydrogen 2.994 N/A LEU 151.A N LYS 147.A O no hydrogen 3.156 N/A ILE 152.A N LEU 148.A O no hydrogen 3.219 N/A ASP 153.A N ARG 149.A O no hydrogen 2.847 N/A ARG 154.A N ARG 150.A O no hydrogen 2.892 N/A THR 155.A N ILE 152.A O no hydrogen 3.156 N/A THR 155.A OG1 LEU 151.A O no hydrogen 2.907 N/A THR 155.A OG1 ILE 152.A O no hydrogen 3.396 N/A SER 156.A N ILE 152.A O no hydrogen 2.831 N/A ALA 158.A N THR 155.A O no hydrogen 3.082 N/A MET 159.A N SER 156.A O no hydrogen 3.309 N/A ALA 160.A N LEU 168.A O no hydrogen 3.036 N/A ASP 163.A N ASN 169.A OD1 no hydrogen 2.909 N/A ARG 165.A N ASP 163.A OD1 no hydrogen 2.756 N/A ARG 165.A NE ASP 163.A OD1 no hydrogen 3.030 N/A ARG 165.A NH2 ASP 163.A OD2 no hydrogen 2.926 N/A TYR 166.A N VAL 164.A O no hydrogen 2.911 N/A TYR 166.A OH ASP 252.A O no hydrogen 2.751 N/A LEU 168.A N ARG 165.A O no hydrogen 2.917 N/A ASN 169.A N TYR 166.A O no hydrogen 3.060 N/A ASN 169.A ND2 ASP 163.A O no hydrogen 2.928 N/A MET 171.A N VAL 209.A O no hydrogen 2.887 N/A LEU 172.A N VAL 183.A O no hydrogen 2.817 N/A LEU 173.A N VAL 207.A O no hydrogen 2.891 N/A GLU 174.A N ARG 181.A O no hydrogen 2.785 N/A VAL 175.A N HIS 205.A O no hydrogen 2.833 N/A ASN 176.A N THR 179.A O no hydrogen 3.223 N/A THR 179.A N ASN 176.A O no hydrogen 3.312 N/A LEU 180.A N LEU 195.A O no hydrogen 2.918 N/A ARG 181.A N GLU 174.A O no hydrogen 2.837 N/A ARG 181.A NE SER 194.A OG no hydrogen 2.812 N/A ARG 181.A NH1 TYR 258.A OH no hydrogen 2.798 N/A SER 182.A N CYS 193.A O no hydrogen 2.839 N/A SER 182.A OG LEU 151.A O no hydrogen 2.841 N/A SER 182.A OG CYS 193.A O no hydrogen 3.449 N/A VAL 183.A N LEU 172.A O no hydrogen 2.952 N/A ALA 184.A N ALA 191.A O no hydrogen 2.923 N/A THR 185.A OG1 ARG 189.A O no hydrogen 2.740 N/A ASP 186.A N ARG 189.A O no hydrogen 3.381 N/A GLY 187.A N THR 185.A OG1 no hydrogen 3.197 N/A HIS 188.A N ASP 186.A OD1 no hydrogen 2.972 N/A ARG 189.A N ASP 186.A OD1 no hydrogen 2.948 N/A ARG 189.A NE ASP 186.A OD2 no hydrogen 2.812 N/A ARG 189.A NH1 ASP 340.A OD2 no hydrogen 2.784 N/A ARG 189.A NH2 ASP 340.A OD2 no hydrogen 3.309 N/A LEU 190.A N VAL 374.A O no hydrogen 2.927 N/A ALA 191.A N ALA 184.A O no hydrogen 2.891 N/A MET 192.A N ALA 372.A O no hydrogen 2.893 N/A CYS 193.A N SER 182.A O no hydrogen 3.027 N/A CYS 193.A SG SER 371.A OG no hydrogen 3.482 N/A SER 194.A N ASP 370.A O no hydrogen 2.917 N/A LEU 195.A N LEU 180.A O no hydrogen 2.863 N/A ILE 199.A N GLY 178.A O no hydrogen 3.187 N/A SER 201.A N ILE 199.A O no hydrogen 2.671 N/A SER 201.A OG ASP 203.A O no hydrogen 3.488 N/A ARG 204.A NH1 GLU 174.A OE1 no hydrogen 3.190 N/A HIS 205.A N VAL 175.A O no hydrogen 2.869 N/A HIS 205.A ND1 ASP 203.A O no hydrogen 3.185 N/A GLN 206.A NE2 GLU 174.A OE1 no hydrogen 2.719 N/A VAL 207.A N LEU 173.A O no hydrogen 3.058 N/A VAL 209.A N MET 171.A O no hydrogen 2.941 N/A ARG 211.A N ASN 169.A O no hydrogen 2.940 N/A ARG 211.A NH1 ALA 160.A O no hydrogen 2.914 N/A ILE 214.A N PRO 210.A O no hydrogen 2.949 N/A LEU 215.A N ARG 211.A O no hydrogen 3.176 N/A GLU 216.A N LYS 212.A O no hydrogen 3.148 N/A LEU 217.A N GLY 213.A O no hydrogen 2.871 N/A ALA 218.A N ILE 214.A O no hydrogen 3.061 N/A ARG 219.A N LEU 215.A O no hydrogen 3.282 N/A ARG 219.A NH1 GLU 216.A OE1 no hydrogen 3.501 N/A LEU 220.A N GLU 216.A O no hydrogen 3.260 N/A LEU 220.A N LEU 217.A O no hydrogen 3.139 N/A LEU 221.A N ALA 218.A O no hydrogen 3.285 N/A THR 222.A N LEU 220.A O no hydrogen 2.955 N/A GLU 223.A N GLN 145.A OE1 no hydrogen 3.207 N/A GLY 226.A N GLU 223.A O no hydrogen 2.924 N/A VAL 228.A N ILE 143.A O no hydrogen 2.784 N/A GLY 229.A N THR 240.A O no hydrogen 2.825 N/A ILE 230.A N PHE 141.A O no hydrogen 2.732 N/A VAL 231.A N ARG 238.A O no hydrogen 2.859 N/A LEU 232.A N LEU 139.A O no hydrogen 2.748 N/A GLY 233.A N HIS 236.A O no hydrogen 2.732 N/A ILE 237.A N SER 248.A O no hydrogen 3.041 N/A ARG 238.A N VAL 231.A O no hydrogen 2.945 N/A ALA 239.A N PHE 246.A O no hydrogen 2.799 N/A THR 240.A N GLY 229.A O no hydrogen 2.832 N/A THR 241.A N PHE 244.A O no hydrogen 2.888 N/A THR 241.A OG1 PHE 244.A O no hydrogen 3.393 N/A PHE 244.A N THR 241.A OG1 no hydrogen 3.101 N/A THR 245.A N VAL 67.A O no hydrogen 2.858 N/A PHE 246.A N ALA 239.A O no hydrogen 2.794 N/A THR 247.A N GLU 65.A O no hydrogen 2.844 N/A SER 248.A N ILE 237.A O no hydrogen 2.989 N/A SER 248.A OG LYS 249.A O no hydrogen 2.838 N/A LYS 249.A N GLU 63.A O no hydrogen 2.962 N/A LEU 250.A N HIS 235.A O no hydrogen 3.002 N/A VAL 251.A N ILE 208.A O no hydrogen 2.769 N/A GLY 253.A N VAL 251.A O no hydrogen 3.048 N/A TYR 258.A N PRO 256.A O no hydrogen 2.682 N/A TYR 258.A OH GLU 174.A OE1 no hydrogen 3.306 N/A TYR 258.A OH GLU 174.A OE2 no hydrogen 2.840 N/A ARG 260.A N ASP 257.A O no hydrogen 3.350 N/A VAL 261.A N TYR 258.A O no hydrogen 2.954 N/A LEU 262.A N GLU 259.A O no hydrogen 3.502 N/A LYS 268.A N LEU 354.A O no hydrogen 2.946 N/A LYS 268.A NZ ASP 267.A OD1 no hydrogen 3.336 N/A LYS 268.A NZ ASP 267.A OD2 no hydrogen 2.967 N/A LYS 268.A NZ SER 355.A O no hydrogen 2.753 N/A VAL 270.A N PHE 352.A O no hydrogen 2.778 N/A VAL 271.A N GLU 323.A O no hydrogen 2.907 N/A GLY 272.A N VAL 350.A O no hydrogen 3.116 N/A ARG 274.A N GLU 348.A O no hydrogen 2.785 N/A ARG 274.A NH1 LEU 342.A O no hydrogen 2.943 N/A GLN 275.A NE2 GLU 279.A OE1 no hydrogen 2.855 N/A GLN 276.A N ASP 273.A OD2 no hydrogen 2.858 N/A LEU 277.A N ASP 273.A O no hydrogen 2.875 N/A ARG 278.A N ARG 274.A O no hydrogen 2.859 N/A ARG 278.A NE LEU 339.A O no hydrogen 2.901 N/A ARG 278.A NH2 LEU 339.A O no hydrogen 3.436 N/A GLU 279.A N GLN 275.A O no hydrogen 2.864 N/A ALA 280.A N GLN 276.A O no hydrogen 2.925 N/A PHE 281.A N LEU 277.A O no hydrogen 2.819 N/A SER 282.A N ARG 278.A O no hydrogen 2.927 N/A SER 282.A OG.B ARG 278.A O no hydrogen 3.023 N/A ARG 283.A N GLU 279.A O no hydrogen 2.975 N/A ARG 283.A NE GLU 318.A OE1 no hydrogen 2.861 N/A ARG 283.A NH2 GLU 318.A OE1 no hydrogen 3.290 N/A ARG 283.A NH2 GLU 318.A OE2 no hydrogen 2.683 N/A THR 284.A N ALA 280.A O no hydrogen 3.009 N/A THR 284.A OG1 ALA 280.A O no hydrogen 3.109 N/A THR 284.A OG1 PHE 281.A O no hydrogen 3.125 N/A ALA 285.A N PHE 281.A O no hydrogen 2.918 N/A ILE 286.A N ARG 283.A O no hydrogen 3.239 N/A LEU 287.A N THR 284.A O no hydrogen 3.093 N/A SER 288.A N ALA 285.A O no hydrogen 3.034 N/A SER 288.A OG ALA 285.A O no hydrogen 2.764 N/A LYS 291.A N ASN 289.A OD1 no hydrogen 3.018 N/A TYR 292.A N ASN 289.A OD1 no hydrogen 3.169 N/A ARG 293.A N ASN 289.A O no hydrogen 2.858 N/A ILE 295.A N PHE 333.A O no hydrogen 2.812 N/A ARG 296.A N GLN 307.A O no hydrogen 2.760 N/A ARG 296.A NH1 GLU 330.A OE2 no hydrogen 3.267 N/A LEU 297.A N ILE 331.A O no hydrogen 2.702 N/A GLN 298.A N LYS 305.A O no hydrogen 2.787 N/A LEU 299.A N LEU 329.A O no hydrogen 2.715 N/A SER 300.A N LEU 303.A O no hydrogen 3.006 N/A GLY 302.A N TYR 324.A O no hydrogen 2.808 N/A LEU 303.A N SER 300.A O no hydrogen 2.986 N/A LEU 304.A N VAL 320.A O no hydrogen 2.835 N/A LYS 305.A N GLN 298.A O no hydrogen 2.890 N/A ILE 306.A N GLU 318.A O no hydrogen 2.734 N/A GLN 307.A N ARG 296.A O no hydrogen 2.839 N/A ALA 308.A N ALA 316.A O no hydrogen 2.899 N/A ASN 309.A ND2 GLU 315.A OE2 no hydrogen 3.557 N/A ASN 310.A N GLU 314.A O no hydrogen 3.357 N/A ASN 310.A ND2 GLU 314.A OE1 no hydrogen 2.892 N/A GLU 312.A N GLU 312.A OE1 no hydrogen 2.998 N/A GLN 313.A N ASN 310.A O no hydrogen 3.054 N/A GLU 314.A N ASN 310.A OD1 no hydrogen 3.016 N/A ALA 316.A N ALA 308.A O no hydrogen 2.901 N/A GLU 318.A N ILE 306.A O no hydrogen 2.903 N/A VAL 320.A N LEU 304.A O no hydrogen 2.736 N/A VAL 322.A N GLY 302.A O no hydrogen 3.204 N/A GLU 323.A N VAL 271.A O no hydrogen 2.776 N/A TYR 324.A OH GLY 327.A O no hydrogen 2.811 N/A LEU 329.A N LEU 299.A O no hydrogen 2.955 N/A ILE 331.A N LEU 297.A O no hydrogen 2.895 N/A PHE 333.A N ILE 295.A O no hydrogen 2.956 N/A VAL 335.A N ARG 293.A O no hydrogen 2.757 N/A SER 336.A OG ASN 334.A OD1 no hydrogen 2.752 N/A TYR 337.A N ASN 334.A OD1 no hydrogen 3.370 N/A LEU 338.A N ASN 334.A O no hydrogen 3.442 N/A LEU 339.A N VAL 335.A O no hydrogen 2.857 N/A ASP 340.A N SER 336.A O no hydrogen 2.895 N/A VAL 341.A N TYR 337.A O no hydrogen 3.227 N/A LEU 342.A N LEU 338.A O no hydrogen 2.986 N/A GLY 343.A N LEU 339.A O no hydrogen 2.974 N/A VAL 344.A N VAL 341.A O no hydrogen 2.992 N/A ILE 345.A N LEU 342.A O no hydrogen 3.282 N/A GLY 346.A N GLU 365.A OE2 no hydrogen 2.681 N/A THR 347.A OG1 GLN 349.A O no hydrogen 2.674 N/A GLN 349.A NE2 GLU 323.A OE2 no hydrogen 3.129 N/A VAL 350.A N GLY 272.A O no hydrogen 2.921 N/A ARG 351.A N HIS 364.A O no hydrogen 2.991 N/A ARG 351.A NE GLU 365.A O no hydrogen 2.959 N/A ARG 351.A NH1 ASP 369.A OD1 no hydrogen 3.332 N/A ARG 351.A NH2 GLU 365.A O no hydrogen 3.124 N/A ARG 351.A NH2 ASP 369.A OD1 no hydrogen 2.689 N/A PHE 352.A N VAL 270.A O no hydrogen 2.872 N/A ILE 353.A N LEU 362.A O no hydrogen 2.725 N/A LEU 354.A N LYS 268.A O no hydrogen 2.818 N/A SER 357.A OG ASN 358.A OD1 no hydrogen 3.540 N/A ASN 358.A N ASP 356.A OD1 no hydrogen 3.159 N/A SER 359.A N ASP 356.A O no hydrogen 3.412 N/A SER 359.A OG ASP 356.A OD1 no hydrogen 2.761 N/A ALA 361.A N VAL 375.A O no hydrogen 2.844 N/A LEU 362.A N ILE 353.A O no hydrogen 2.983 N/A VAL 363.A N TYR 373.A O no hydrogen 2.802 N/A HIS 364.A N ARG 351.A O no hydrogen 2.975 N/A HIS 364.A ND1 SER 371.A O no hydrogen 2.857 N/A ALA 366.A N THR 347.A OG1 no hydrogen 2.919 N/A ASN 368.A ND2 GLU 365.A OE1 no hydrogen 2.988 N/A ASN 368.A ND2 ASP 367.A OD1 no hydrogen 2.914 N/A ASP 370.A N ASN 368.A OD1 no hydrogen 2.931 N/A ALA 372.A N MET 192.A O no hydrogen 2.924 N/A TYR 373.A N VAL 363.A O no hydrogen 2.972 N/A TYR 373.A OH ARG 154.A O no hydrogen 2.746 N/A VAL 374.A N LEU 190.A O no hydrogen 2.858 N/A VAL 375.A N ALA 361.A O no hydrogen 3.025 N/A MET 376.A N HIS 188.A O no hydrogen 3.476 N/A MET 378.A N GLY 332.A O no hydrogen 2.841 N/A