Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4trz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): PHE 1.A N GLU 3.A OE1 no hydrogen 2.498 N/A GLU 3.A N GLU 3.A OE1 no hydrogen 2.703 N/A MET 4.A N PHE 1.A O no hydrogen 3.027 N/A VAL 5.A N VAL 2.A O no hydrogen 3.136 N/A ASP 6.A N SER 175.A OG no hydrogen 2.495 N/A ASN 7.A ND2 MET 176.A O no hydrogen 2.831 N/A LEU 8.A N GLY 174.A O no hydrogen 2.869 N/A ARG 9.A N TYR 17.A O no hydrogen 3.107 N/A SER 12.A OG GLU 341.A OE1 no hydrogen 2.454 N/A GLN 14.A N LYS 11.A O no hydrogen 3.220 N/A GLY 15.A N LYS 11.A O no hydrogen 2.707 N/A TYR 16.A OH CYS 157.A O no hydrogen 3.141 N/A TYR 16.A OH GLU 341.A OE1 no hydrogen 2.773 N/A TYR 17.A N ARG 9.A O no hydrogen 2.659 N/A VAL 18.A N ILE 31.A O no hydrogen 2.702 N/A MET 20.A N LEU 29.A O no hydrogen 2.908 N/A THR 21.A N SER 88.A O no hydrogen 2.937 N/A VAL 22.A N GLN 27.A O no hydrogen 2.932 N/A GLY 23.A N LEU 86.A O no hydrogen 2.837 N/A SER 24.A N SER 59.A OG no hydrogen 3.241 N/A GLN 27.A N VAL 22.A O no hydrogen 2.949 N/A GLN 27.A NE2 GLN 55.A O no hydrogen 2.944 N/A LEU 29.A N MET 20.A O no hydrogen 2.790 N/A ASN 30.A N GLU 118.A OE2 no hydrogen 3.155 N/A ASN 30.A ND2 ASN 116.A O no hydrogen 3.265 N/A ASN 30.A ND2 ASN 116.A OD1 no hydrogen 3.572 N/A ILE 31.A N VAL 18.A O no hydrogen 2.703 N/A LEU 32.A N GLY 119.A O no hydrogen 2.492 N/A VAL 33.A N TYR 16.A O no hydrogen 3.012 N/A ASP 34.A N LEU 121.A O no hydrogen 2.599 N/A THR 35.A N SER 231.A OG no hydrogen 3.332 N/A THR 35.A OG1 VAL 229.A O no hydrogen 3.180 N/A GLY 36.A N ASP 34.A OD1 no hydrogen 2.699 N/A SER 37.A OG ASP 34.A OD2 no hydrogen 2.529 N/A ASN 39.A ND2 ILE 128.A O no hydrogen 3.630 N/A ALA 41.A N ILE 120.A O no hydrogen 3.004 N/A VAL 42.A N ALA 102.A O no hydrogen 2.991 N/A GLY 43.A N GLU 118.A O no hydrogen 3.430 N/A PHE 49.A N HIS 47.A ND1 no hydrogen 2.870 N/A LEU 50.A N HIS 47.A O no hydrogen 3.047 N/A ARG 52.A NE GLU 118.A OE1 no hydrogen 3.073 N/A TYR 54.A N GLY 43.A O no hydrogen 2.236 N/A TYR 54.A OH ASP 85.A OD2 no hydrogen 2.516 N/A GLN 55.A N GLN 27.A OE1 no hydrogen 3.388 N/A ARG 56.A NH1 TYR 62.A OH no hydrogen 3.245 N/A ARG 56.A NH1 GLU 81.A OE1 no hydrogen 2.576 N/A GLN 57.A N GLN 57.A OE1 no hydrogen 2.745 N/A SER 59.A OG ASP 85.A OD1 no hydrogen 2.747 N/A SER 59.A OG ASP 85.A OD2 no hydrogen 2.448 N/A SER 60.A N SER 24.A O no hydrogen 2.624 N/A SER 60.A OG SER 24.A O no hydrogen 3.410 N/A THR 61.A OG1 ASP 85.A OD1 no hydrogen 2.446 N/A ARG 63.A N THR 84.A O no hydrogen 2.590 N/A LEU 65.A N LEU 82.A O no hydrogen 3.356 N/A ARG 66.A N ASP 64.A OD1 no hydrogen 2.201 N/A VAL 69.A N GLY 80.A O no hydrogen 2.853 N/A VAL 71.A N TRP 78.A O no hydrogen 2.501 N/A TYR 73.A N GLY 76.A O no hydrogen 3.156 N/A LYS 77.A N ASP 108.A O no hydrogen 2.743 N/A TRP 78.A N VAL 71.A O no hydrogen 3.133 N/A GLU 79.A N GLU 106.A O no hydrogen 3.158 N/A GLY 80.A N VAL 69.A O no hydrogen 2.577 N/A GLU 81.A N ALA 103.A O no hydrogen 2.957 N/A LEU 82.A N LYS 67.A O no hydrogen 3.124 N/A GLY 83.A N ILE 101.A O no hydrogen 2.914 N/A THR 84.A N ARG 63.A O no hydrogen 2.743 N/A ASP 85.A N ALA 99.A O no hydrogen 3.274 N/A VAL 87.A N VAL 97.A O no hydrogen 2.572 N/A SER 88.A N THR 21.A O no hydrogen 3.032 N/A SER 88.A OG VAL 95.A O no hydrogen 3.225 N/A GLY 92.A N ILE 89.A O no hydrogen 3.167 N/A VAL 95.A N PRO 93.A O no hydrogen 2.912 N/A VAL 97.A N VAL 87.A O no hydrogen 2.985 N/A ARG 98.A N GLN 145.A OE1 no hydrogen 3.305 N/A ALA 99.A N ASP 85.A O no hydrogen 3.180 N/A ASN 100.A ND2 GLU 136.A O no hydrogen 3.471 N/A ILE 101.A N GLY 83.A O no hydrogen 2.803 N/A ALA 103.A N GLU 81.A O no hydrogen 2.938 N/A ILE 104.A N VAL 42.A O no hydrogen 2.652 N/A THR 105.A N GLU 79.A O no hydrogen 3.298 N/A THR 105.A OG1 GLU 79.A O no hydrogen 3.312 N/A ASP 108.A N LYS 77.A O no hydrogen 2.747 N/A SER 115.A N ILE 112.A O no hydrogen 3.400 N/A SER 115.A OG ILE 112.A O no hydrogen 2.941 N/A SER 115.A OG TRP 117.A O no hydrogen 3.227 N/A TRP 117.A N SER 115.A OG no hydrogen 3.272 N/A GLU 118.A N ASN 30.A O no hydrogen 2.727 N/A ILE 120.A N ALA 41.A O no hydrogen 2.903 N/A LEU 121.A N LEU 32.A O no hydrogen 2.605 N/A LEU 123.A N ASP 34.A O no hydrogen 2.587 N/A ALA 124.A N SER 37.A O no hydrogen 3.067 N/A TYR 125.A N TRP 199.A O no hydrogen 3.194 N/A ALA 129.A N ALA 126.A O no hydrogen 2.659 N/A ARG 130.A N ASN 39.A OD1 no hydrogen 2.713 N/A LEU 135.A N ASP 132.A O no hydrogen 3.101 N/A LEU 142.A N PHE 138.A O no hydrogen 2.955 N/A VAL 143.A N PHE 139.A O no hydrogen 2.868 N/A LYS 144.A N ASP 140.A O no hydrogen 2.798 N/A GLN 145.A N SER 141.A O no hydrogen 2.889 N/A GLN 145.A NE2 ARG 98.A O no hydrogen 2.617 N/A THR 146.A N VAL 143.A O no hydrogen 3.420 N/A THR 146.A OG1 LEU 142.A O no hydrogen 2.369 N/A VAL 148.A N THR 146.A OG1 no hydrogen 3.308 N/A SER 153.A N ILE 177.A O no hydrogen 2.780 N/A SER 153.A OG GLY 180.A O no hydrogen 2.687 N/A LEU 154.A N VAL 345.A O no hydrogen 2.705 N/A GLN 155.A N SER 175.A O no hydrogen 2.792 N/A CYS 157.A N GLY 173.A O no hydrogen 2.223 N/A SER 166.A N ASN 164.A OD1 no hydrogen 3.087 N/A VAL 168.A N ASN 164.A O no hydrogen 2.306 N/A LEU 169.A N GLN 165.A O no hydrogen 3.115 N/A ALA 170.A N SER 166.A O no hydrogen 3.456 N/A SER 171.A N GLU 167.A O no hydrogen 2.545 N/A SER 171.A OG GLU 167.A O no hydrogen 2.691 N/A SER 175.A N GLN 155.A O no hydrogen 2.843 N/A SER 175.A OG GLN 155.A OE1 no hydrogen 3.415 N/A ILE 177.A N SER 153.A O no hydrogen 2.887 N/A ASP 182.A N TYR 344.A OH no hydrogen 3.260 N/A SER 184.A OG ASP 182.A OD2 no hydrogen 2.474 N/A LEU 185.A N ASP 182.A O no hydrogen 2.971 N/A TYR 186.A N HIS 183.A O no hydrogen 3.169 N/A THR 187.A N VAL 358.A O no hydrogen 3.252 N/A TRP 191.A N PHE 356.A O no hydrogen 2.970 N/A THR 193.A N ILE 354.A O no hydrogen 2.945 N/A THR 193.A OG1 MET 290.A O no hydrogen 2.929 N/A ILE 195.A N LYS 352.A O no hydrogen 2.987 N/A ARG 196.A N GLU 202.A O no hydrogen 3.364 N/A ARG 196.A NH1 GLU 202.A OE2 no hydrogen 3.154 N/A TRP 199.A N ARG 197.A O no hydrogen 2.774 N/A TRP 199.A NE1 GLU 202.A OE1 no hydrogen 2.778 N/A TYR 201.A OH LEU 123.A O no hydrogen 2.341 N/A VAL 203.A N SER 227.A O no hydrogen 2.635 N/A ILE 205.A N ASN 223.A OD1 no hydrogen 2.961 N/A VAL 206.A N TYR 288.A O no hydrogen 2.908 N/A GLU 209.A N SER 286.A O no hydrogen 3.015 N/A ILE 210.A N GLN 213.A O no hydrogen 2.692 N/A ASN 211.A N VAL 284.A O no hydrogen 2.834 N/A GLN 213.A N ILE 210.A O no hydrogen 2.966 N/A LEU 215.A N VAL 208.A O no hydrogen 3.295 N/A LYS 216.A N ASP 214.A OD1 no hydrogen 2.213 N/A LYS 220.A N ASP 218.A OD1 no hydrogen 3.241 N/A GLU 221.A N ASP 218.A O no hydrogen 2.568 N/A TYR 222.A N CYS 219.A O no hydrogen 3.220 N/A ASN 223.A N LYS 220.A O no hydrogen 2.962 N/A ASN 223.A ND2 ILE 205.A O no hydrogen 2.827 N/A ASN 223.A ND2 CYS 219.A O no hydrogen 3.276 N/A ASN 223.A ND2 CYS 384.A O no hydrogen 3.449 N/A SER 227.A OG ASN 223.A OD1 no hydrogen 2.219 N/A ILE 228.A N THR 333.A O no hydrogen 3.176 N/A VAL 229.A N TYR 201.A O no hydrogen 3.186 N/A ASP 230.A N MET 335.A O no hydrogen 3.029 N/A SER 231.A N THR 35.A OG1 no hydrogen 2.747 N/A SER 231.A OG VAL 33.A O no hydrogen 2.887 N/A GLY 232.A N ASP 230.A OD1 no hydrogen 2.266 N/A THR 233.A OG1 ASP 230.A OD2 no hydrogen 2.697 N/A THR 234.A OG1 SER 12.A O no hydrogen 2.506 N/A THR 234.A OG1 GLY 13.A O no hydrogen 3.525 N/A LEU 236.A N ALA 325.A O no hydrogen 2.886 N/A ARG 237.A N VAL 334.A O no hydrogen 3.156 N/A LEU 238.A N SER 327.A O no hydrogen 2.744 N/A PHE 243.A N PRO 239.A O no hydrogen 2.670 N/A GLU 244.A N LYS 240.A O no hydrogen 2.943 N/A ALA 245.A N LYS 241.A O no hydrogen 3.203 N/A ALA 246.A N VAL 242.A O no hydrogen 3.071 N/A VAL 247.A N PHE 243.A O no hydrogen 3.040 N/A LYS 248.A N GLU 244.A O no hydrogen 3.185 N/A SER 249.A N ALA 245.A O no hydrogen 3.220 N/A ILE 250.A N ALA 246.A O no hydrogen 2.505 N/A LYS 251.A N VAL 247.A O no hydrogen 2.843 N/A ALA 252.A N LYS 248.A O no hydrogen 3.208 N/A SER 254.A N ILE 250.A O no hydrogen 3.116 N/A SER 254.A OG ILE 250.A O no hydrogen 2.777 N/A SER 254.A OG LYS 251.A O no hydrogen 2.845 N/A SER 255.A N ALA 252.A O no hydrogen 3.086 N/A SER 255.A OG LYS 251.A O no hydrogen 2.676 N/A SER 255.A OG ALA 252.A O no hydrogen 2.669 N/A GLU 257.A N SER 254.A O no hydrogen 3.097 N/A PHE 263.A N PRO 260.A O no hydrogen 2.328 N/A GLY 266.A N GLY 262.A O no hydrogen 3.282 N/A VAL 270.A N TYR 322.A O no hydrogen 2.943 N/A TRP 272.A N ASP 320.A O no hydrogen 2.884 N/A GLY 275.A N ASP 320.A OD2 no hydrogen 2.942 N/A THR 276.A N GLN 273.A O no hydrogen 2.849 N/A THR 276.A OG1 GLN 273.A O no hydrogen 2.298 N/A PHE 282.A N TRP 279.A O no hydrogen 2.413 N/A VAL 284.A N ASN 211.A OD1 no hydrogen 2.974 N/A ILE 285.A N ILE 302.A O no hydrogen 3.071 N/A SER 286.A N GLU 209.A O no hydrogen 2.749 N/A SER 286.A OG THR 301.A OG1 no hydrogen 3.072 N/A LEU 287.A N ILE 300.A O no hydrogen 2.971 N/A TYR 288.A N ARG 207.A O no hydrogen 3.072 N/A TYR 288.A OH GLU 209.A OE1 no hydrogen 2.872 N/A LEU 289.A N PHE 298.A O no hydrogen 2.654 N/A GLY 291.A N GLN 296.A O no hydrogen 2.755 N/A GLN 296.A N VAL 293.A O no hydrogen 3.251 N/A SER 297.A N PHE 376.A O no hydrogen 3.143 N/A SER 297.A OG THR 378.A OG1 no hydrogen 2.736 N/A PHE 298.A N LEU 289.A O no hydrogen 3.110 N/A ARG 299.A N GLU 373.A O no hydrogen 3.172 N/A ARG 299.A NE GLU 373.A OE2 no hydrogen 2.724 N/A ARG 299.A NH1 TYR 288.A OH no hydrogen 2.730 N/A ARG 299.A NH2 GLU 373.A OE2 no hydrogen 2.670 N/A ILE 300.A N LEU 287.A O no hydrogen 2.909 N/A THR 301.A N ALA 371.A O no hydrogen 3.060 N/A THR 301.A OG1 SER 286.A OG no hydrogen 3.072 N/A ILE 302.A N ILE 285.A O no hydrogen 2.744 N/A GLN 305.A N GLN 305.A OE1 no hydrogen 3.051 N/A GLN 306.A N LEU 303.A O no hydrogen 2.785 N/A TYR 307.A OH PRO 283.A O no hydrogen 3.167 N/A LEU 308.A N PRO 304.A O no hydrogen 2.778 N/A ARG 309.A N LYS 323.A O no hydrogen 2.721 N/A VAL 311.A N CYS 321.A O no hydrogen 2.956 N/A SER 317.A N ALA 315.A O no hydrogen 2.586 N/A SER 317.A OG THR 316.A O no hydrogen 2.853 N/A GLN 318.A NE2 SER 317.A O no hydrogen 3.531 N/A CYS 321.A SG ASP 319.A O no hydrogen 2.831 N/A TYR 322.A N VAL 270.A O no hydrogen 3.075 N/A LYS 323.A N ARG 309.A O no hydrogen 2.599 N/A ALA 325.A N TYR 307.A O no hydrogen 2.571 N/A SER 327.A N LEU 236.A O no hydrogen 2.784 N/A SER 329.A N LEU 238.A O no hydrogen 2.862 N/A SER 329.A OG THR 331.A OG1 no hydrogen 3.121 N/A SER 329.A OG GLY 332.A O no hydrogen 2.681 N/A THR 331.A N SER 329.A OG no hydrogen 2.947 N/A THR 331.A OG1 SER 329.A OG no hydrogen 3.121 N/A THR 333.A OG1 TYR 222.A O no hydrogen 2.378 N/A VAL 334.A N ARG 237.A O no hydrogen 2.901 N/A MET 335.A N ILE 228.A O no hydrogen 2.908 N/A ALA 337.A N THR 233.A O no hydrogen 2.791 N/A MET 340.A N GLY 336.A O no hydrogen 3.120 N/A GLU 341.A N VAL 338.A O no hydrogen 3.445 N/A TYR 344.A N ALA 357.A O no hydrogen 2.616 N/A VAL 345.A N LEU 154.A O no hydrogen 3.138 N/A VAL 346.A N GLY 355.A O no hydrogen 2.708 N/A PHE 347.A N PHE 152.A O no hydrogen 3.036 N/A ASP 348.A N ARG 353.A O no hydrogen 2.850 N/A ARG 349.A N PHE 347.A O no hydrogen 3.047 N/A ARG 349.A NE ASN 150.A OD1 no hydrogen 3.297 N/A ARG 349.A NH1 LEU 123.A O no hydrogen 3.086 N/A ALA 350.A N ASN 150.A O no hydrogen 3.235 N/A ARG 351.A N ASP 348.A OD1 no hydrogen 3.301 N/A LYS 352.A N ARG 349.A O no hydrogen 3.027 N/A ARG 353.A N ASP 348.A O no hydrogen 2.873 N/A ARG 353.A NE ASP 348.A OD2 no hydrogen 3.128 N/A ARG 353.A NH1 GLU 292.A OE1 no hydrogen 3.185 N/A ARG 353.A NH2 ASP 348.A OD2 no hydrogen 3.413 N/A ILE 354.A N THR 193.A O no hydrogen 2.811 N/A GLY 355.A N VAL 346.A O no hydrogen 2.755 N/A PHE 356.A N TRP 191.A O no hydrogen 2.653 N/A ALA 357.A N TYR 344.A O no hydrogen 2.914 N/A SER 359.A N GLY 342.A O no hydrogen 2.898 N/A CYS 361.A SG LEU 156.A O no hydrogen 3.986 N/A CYS 361.A SG CYS 361.A O no hydrogen 2.303 N/A HIS 362.A N ALA 360.A O no hydrogen 2.978 N/A PHE 367.A N ASP 365.A OD1 no hydrogen 3.464 N/A ARG 368.A N ASP 365.A O no hydrogen 3.004 N/A ARG 368.A NE ASP 365.A OD2 no hydrogen 2.688 N/A ARG 368.A NH1 PHE 282.A O no hydrogen 2.838 N/A ARG 368.A NH2 ASP 365.A OD2 no hydrogen 3.297 N/A GLU 373.A N ARG 299.A O no hydrogen 2.909 N/A PHE 376.A N SER 297.A O no hydrogen 2.781 N/A THR 378.A OG1 SER 297.A OG no hydrogen 2.736 N/A ASP 383.A N ASP 380.A O no hydrogen 3.061 N/A CYS 384.A N MET 381.A O no hydrogen 2.711 N/A CYS 384.A SG ASP 380.A O no hydrogen 3.816 N/A GLY 385.A N GLU 382.A O no hydrogen 2.626 N/A