Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4uqv_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 5.A N GLU 2.A O no hydrogen 2.992 N/A VAL 6.A N TYR 3.A O no hydrogen 2.935 N/A PHE 9.A N ASP 5.A O no hydrogen 3.060 N/A PHE 9.A N VAL 6.A O no hydrogen 3.225 N/A ILE 10.A N VAL 6.A O no hydrogen 3.433 N/A ARG 11.A N PRO 7.A O no hydrogen 3.383 N/A ASP 12.A N LYS 8.A O no hydrogen 3.470 N/A VAL 13.A N PHE 9.A O no hydrogen 3.040 N/A SER 14.A N ILE 10.A O no hydrogen 2.343 N/A SER 14.A OG ILE 10.A O no hydrogen 2.474 N/A ILE 15.A N ARG 11.A O no hydrogen 2.647 N/A LYS 16.A N ASP 12.A O no hydrogen 2.767 N/A GLN 17.A N VAL 13.A O no hydrogen 2.797 N/A GLN 17.A N SER 14.A O no hydrogen 2.949 N/A HIS 18.A N SER 14.A O no hydrogen 3.135 N/A GLU 19.A N ILE 15.A O no hydrogen 2.973 N/A TRP 20.A N LYS 16.A O no hydrogen 3.251 N/A TRP 20.A NE1 ASN 337.A OD1 no hydrogen 2.589 N/A MET 21.A N GLN 17.A O no hydrogen 3.111 N/A ARG 22.A NH1 ASP 418.A OD2 no hydrogen 2.540 N/A ARG 22.A NH2 ASP 418.A OD2 no hydrogen 2.966 N/A GLU 23.A N GLU 19.A O no hydrogen 3.204 N/A GLU 23.A N TRP 20.A O no hydrogen 3.222 N/A SER 24.A N MET 21.A O no hydrogen 3.097 N/A SER 24.A OG TRP 20.A O no hydrogen 2.373 N/A ILE 25.A N ASN 337.A O no hydrogen 3.145 N/A LYS 26.A NZ MET 21.A O no hydrogen 2.888 N/A LYS 26.A NZ SER 24.A O no hydrogen 3.159 N/A LEU 27.A N ILE 339.A O no hydrogen 2.508 N/A ASN 32.A ND2 LYS 223.A O no hydrogen 3.654 N/A ASN 32.A ND2 GLN 364.A OE1 no hydrogen 2.831 N/A ILE 33.A N ASN 32.A OD1 no hydrogen 2.489 N/A SER 35.A OG GLU 269.A OE2 no hydrogen 3.180 N/A SER 35.A OG ASP 415.A OD1 no hydrogen 3.056 N/A LEU 36.A N ASP 415.A OD2 no hydrogen 2.884 N/A ARG 39.A N SER 35.A O no hydrogen 3.442 N/A ARG 39.A NH2 THR 34.A O no hydrogen 3.082 N/A ARG 39.A NH2 GLY 419.A O no hydrogen 2.674 N/A GLU 40.A N LEU 36.A O no hydrogen 2.906 N/A ALA 41.A N ALA 37.A O no hydrogen 2.919 N/A CYS 42.A N VAL 38.A O no hydrogen 2.897 N/A CYS 42.A SG VAL 38.A O no hydrogen 3.115 N/A CYS 42.A SG HIS 258.A O no hydrogen 4.040 N/A CYS 42.A SG HIS 259.A ND1 no hydrogen 4.029 N/A ALA 43.A N GLU 40.A O no hydrogen 3.021 N/A THR 44.A OG1 ALA 41.A O no hydrogen 2.402 N/A MET 47.A N THR 44.A O no hydrogen 2.827 N/A HIS 48.A N ASP 45.A O no hydrogen 2.858 N/A ARG 49.A N PHE 46.A O no hydrogen 3.251 N/A CYS 60.A SG GLN 58.A O no hydrogen 3.516 N/A ASP 64.A N CYS 60.A O no hydrogen 2.524 N/A GLU 65.A N LYS 61.A O no hydrogen 2.953 N/A VAL 66.A N TYR 62.A O no hydrogen 2.918 N/A GLU 67.A N ILE 63.A O no hydrogen 2.936 N/A THR 68.A N ASP 64.A O no hydrogen 2.916 N/A THR 68.A OG1 ASP 64.A O no hydrogen 2.746 N/A LEU 69.A N GLU 65.A O no hydrogen 2.985 N/A CYS 70.A N VAL 66.A O no hydrogen 2.913 N/A CYS 70.A SG VAL 66.A O no hydrogen 3.073 N/A CYS 70.A SG LYS 260.A O no hydrogen 3.064 N/A ILE 71.A N GLU 67.A O no hydrogen 2.939 N/A GLU 72.A N THR 68.A O no hydrogen 2.984 N/A LEU 73.A N LEU 69.A O no hydrogen 2.931 N/A SER 74.A N CYS 70.A O no hydrogen 2.898 N/A SER 74.A OG CYS 70.A O no hydrogen 2.628 N/A LYS 75.A N ILE 71.A O no hydrogen 2.956 N/A LYS 75.A NZ GLU 72.A OE2 no hydrogen 3.123 N/A GLU 76.A N GLU 72.A O no hydrogen 2.914 N/A LEU 77.A N LEU 73.A O no hydrogen 2.915 N/A LEU 77.A N SER 74.A O no hydrogen 3.120 N/A PHE 78.A N SER 74.A O no hydrogen 3.327 N/A ALA 80.A N LYS 75.A O no hydrogen 3.403 N/A ASN 84.A N ILE 233.A O no hydrogen 2.910 N/A GLN 86.A N ASN 84.A OD1 no hydrogen 3.142 N/A GLN 86.A NE2 VAL 247.A O no hydrogen 3.115 N/A ALA 93.A N SER 89.A O no hydrogen 3.155 N/A ASN 94.A N GLY 90.A O no hydrogen 2.924 N/A ASN 94.A ND2 SER 120.A OG no hydrogen 3.308 N/A ASN 94.A ND2 ASP 193.A OD2 no hydrogen 2.968 N/A LEU 95.A N VAL 91.A O no hydrogen 2.892 N/A ALA 96.A N VAL 92.A O no hydrogen 2.936 N/A VAL 97.A N ALA 93.A O no hydrogen 2.957 N/A PHE 98.A N ASN 94.A O no hydrogen 2.868 N/A PHE 99.A N LEU 95.A O no hydrogen 2.915 N/A ALA 100.A N ALA 96.A O no hydrogen 2.934 N/A GLU 101.A N VAL 97.A O no hydrogen 2.875 N/A THR 102.A N PHE 98.A O no hydrogen 2.729 N/A THR 102.A OG1 PHE 98.A O no hydrogen 2.414 N/A LYS 103.A NZ ASP 106.A OD2 no hydrogen 3.094 N/A GLY 105.A N ARG 130.A O no hydrogen 3.398 N/A ASP 106.A N LYS 103.A O no hydrogen 3.321 N/A LEU 108.A N LYS 133.A O no hydrogen 2.777 N/A ALA 110.A N ILE 135.A O no hydrogen 3.063 N/A GLY 116.A N VAL 113.A O no hydrogen 3.163 N/A GLY 117.A N SER 112.A O no hydrogen 2.356 N/A SER 120.A OG ILE 119.A O no hydrogen 2.290 N/A HIS 121.A N HIS 118.A O no hydrogen 3.333 N/A SER 125.A N TRP 122.A O no hydrogen 3.243 N/A ALA 126.A N SER 125.A OG no hydrogen 2.692 N/A GLY 128.A N TRP 122.A O no hydrogen 3.218 N/A GLY 128.A N SER 125.A O no hydrogen 2.646 N/A ILE 129.A N ALA 126.A O no hydrogen 3.133 N/A ARG 130.A NE THR 102.A O no hydrogen 2.408 N/A ARG 130.A NH2 THR 102.A O no hydrogen 2.898 N/A LYS 133.A N GLY 105.A O no hydrogen 3.469 N/A ILE 135.A N LEU 108.A O no hydrogen 2.929 N/A HIS 137.A N ALA 110.A O no hydrogen 3.416 N/A HIS 137.A NE2 LEU 164.A O no hydrogen 2.685 N/A GLU 142.A N GLU 142.A OE1 no hydrogen 2.519 N/A ASN 145.A ND2 PRO 173.A O no hydrogen 2.316 N/A ILE 146.A N ASN 145.A OD1 no hydrogen 2.554 N/A ASP 147.A N PRO 138.A O no hydrogen 2.739 N/A MET 151.A N ASP 147.A O no hydrogen 3.317 N/A VAL 152.A N ALA 148.A O no hydrogen 2.906 N/A LYS 153.A N ASP 149.A O no hydrogen 2.979 N/A LYS 154.A N ALA 150.A O no hydrogen 2.863 N/A LYS 154.A NZ ASN 136.A O no hydrogen 3.391 N/A LYS 154.A NZ ASN 136.A OD1 no hydrogen 3.403 N/A ILE 155.A N MET 151.A O no hydrogen 2.881 N/A GLU 157.A N LYS 153.A O no hydrogen 2.902 N/A GLU 158.A N LYS 154.A O no hydrogen 2.905 N/A LYS 159.A N ILE 155.A O no hydrogen 2.946 N/A LYS 161.A N LYS 107.A O no hydrogen 2.674 N/A LYS 161.A NZ ASP 106.A OD2 no hydrogen 2.727 N/A LEU 162.A N LYS 107.A O no hydrogen 3.155 N/A ILE 163.A N LYS 189.A O no hydrogen 2.970 N/A LEU 164.A N MET 109.A O no hydrogen 2.957 N/A PHE 165.A N ALA 191.A O no hydrogen 2.925 N/A GLY 166.A N HIS 174.A ND1 no hydrogen 3.161 N/A SER 168.A OG GLY 116.A O no hydrogen 3.033 N/A SER 168.A OG GLY 117.A O no hydrogen 2.927 N/A LEU 169.A N GLY 116.A O no hydrogen 2.687 N/A HIS 174.A N GLN 207.A OE1 no hydrogen 2.619 N/A VAL 176.A N HIS 174.A O no hydrogen 2.607 N/A ASP 178.A N PRO 175.A O no hydrogen 3.427 N/A ALA 182.A N GLU 181.A OE1 no hydrogen 2.775 N/A ALA 183.A N ALA 179.A O no hydrogen 2.903 N/A GLN 184.A N TYR 180.A O no hydrogen 2.896 N/A GLU 185.A N GLU 181.A O no hydrogen 2.929 N/A VAL 186.A N ALA 182.A O no hydrogen 2.905 N/A GLY 187.A N ALA 183.A O no hydrogen 2.849 N/A ALA 188.A N ALA 183.A O no hydrogen 3.148 N/A LYS 189.A NZ GLU 215.A OE1 no hydrogen 3.068 N/A LYS 189.A NZ GLU 215.A OE2 no hydrogen 2.416 N/A ALA 191.A N ILE 163.A O no hydrogen 2.839 N/A TYR 192.A N TYR 216.A O no hydrogen 2.585 N/A TYR 192.A OH GLN 207.A OE1 no hydrogen 3.242 N/A ASP 193.A N PHE 165.A O no hydrogen 2.907 N/A GLY 194.A N MET 218.A O no hydrogen 2.534 N/A ALA 195.A N ASP 193.A OD1 no hydrogen 3.125 N/A ILE 201.A N VAL 197.A O no hydrogen 3.104 N/A ALA 202.A N LEU 198.A O no hydrogen 2.932 N/A GLY 203.A N GLY 199.A O no hydrogen 3.053 N/A GLY 203.A N LEU 200.A O no hydrogen 3.198 N/A LYS 204.A N ILE 201.A O no hydrogen 3.109 N/A LYS 204.A NZ LEU 77.A O no hydrogen 3.492 N/A GLN 205.A N LEU 200.A O no hydrogen 3.044 N/A GLN 205.A NE2 GLY 203.A O no hydrogen 3.556 N/A GLN 207.A NE2 HIS 174.A O no hydrogen 3.591 N/A GLN 207.A NE2 GLU 212.A OE1 no hydrogen 2.665 N/A ARG 211.A N ASP 208.A O no hydrogen 3.199 N/A ARG 211.A NH2 PHE 78.A O no hydrogen 3.529 N/A GLU 212.A N PRO 209.A O no hydrogen 2.873 N/A ALA 214.A N PRO 209.A O no hydrogen 3.018 N/A GLU 215.A N ILE 190.A O no hydrogen 2.463 N/A TYR 216.A N ILE 190.A O no hydrogen 3.259 N/A TYR 216.A OH GLU 101.A OE2 no hydrogen 2.515 N/A LEU 217.A N LEU 234.A O no hydrogen 2.895 N/A MET 218.A N TYR 192.A O no hydrogen 2.982 N/A GLY 219.A N VAL 232.A O no hydrogen 2.936 N/A SER 220.A OG ALA 195.A O no hydrogen 2.622 N/A THR 221.A N GLY 230.A O no hydrogen 3.183 N/A THR 221.A OG1 PRO 228.A O no hydrogen 2.605 N/A LYS 223.A N SER 220.A O no hydrogen 3.413 N/A LYS 223.A NZ SER 220.A OG no hydrogen 3.180 N/A THR 224.A OG1 HIS 196.A O no hydrogen 3.167 N/A VAL 232.A N GLY 219.A O no hydrogen 2.916 N/A ILE 233.A N ASN 84.A O no hydrogen 2.910 N/A THR 235.A N HIS 82.A O no hydrogen 2.915 N/A THR 236.A N THR 235.A OG1 no hydrogen 2.495 N/A GLU 238.A N THR 236.A OG1 no hydrogen 2.893 N/A ASN 239.A N THR 236.A OG1 no hydrogen 3.317 N/A ASN 239.A ND2 GLU 215.A OE2 no hydrogen 2.787 N/A ASN 239.A ND2 THR 235.A OG1 no hydrogen 2.932 N/A ALA 240.A N LYS 237.A O no hydrogen 3.131 N/A ILE 243.A N ASN 239.A O no hydrogen 2.941 N/A ASP 244.A N ALA 240.A O no hydrogen 2.890 N/A SER 245.A N ASP 241.A O no hydrogen 2.931 N/A SER 245.A OG ASP 241.A O no hydrogen 2.911 N/A SER 245.A OG ASP 241.A OD1 no hydrogen 3.289 N/A VAL 247.A N ASP 244.A O no hydrogen 3.244 N/A PHE 248.A N GLY 250.A O no hydrogen 3.338 N/A SER 253.A OG ASN 254.A O no hydrogen 3.081 N/A SER 253.A OG ASN 254.A OD1 no hydrogen 2.945 N/A ASN 254.A ND2 ARG 49.A O no hydrogen 3.665 N/A HIS 255.A NE2 GLN 86.A OE1 no hydrogen 2.653 N/A LYS 260.A N HIS 256.A O no hydrogen 2.980 N/A ALA 261.A N LEU 257.A O no hydrogen 2.904 N/A GLY 262.A N HIS 258.A O no hydrogen 2.900 N/A LEU 263.A N HIS 259.A O no hydrogen 2.880 N/A ALA 264.A N LYS 260.A O no hydrogen 2.908 N/A ILE 265.A N GLY 262.A O no hydrogen 3.201 N/A LEU 267.A N LEU 263.A O no hydrogen 2.934 N/A GLU 269.A N ILE 265.A O no hydrogen 2.871 N/A MET 270.A N ALA 266.A O no hydrogen 2.911 N/A LEU 271.A N LEU 267.A O no hydrogen 2.913 N/A GLU 272.A N ALA 268.A O no hydrogen 2.924 N/A PHE 273.A N GLU 269.A O no hydrogen 2.881 N/A TYR 277.A N PHE 273.A O no hydrogen 2.936 N/A TYR 277.A OH THR 224.A O no hydrogen 3.245 N/A ALA 278.A N GLY 274.A O no hydrogen 2.904 N/A LYS 279.A N GLU 275.A O no hydrogen 2.931 N/A GLN 280.A N ALA 276.A O no hydrogen 2.936 N/A GLN 280.A NE2 ASN 284.A OD1 no hydrogen 2.961 N/A GLN 280.A NE2 GLU 373.A OE1 no hydrogen 3.463 N/A VAL 281.A N TYR 277.A O no hydrogen 2.910 N/A ILE 282.A N ALA 278.A O no hydrogen 2.933 N/A LYS 283.A N LYS 279.A O no hydrogen 2.928 N/A ASN 284.A N GLN 280.A O no hydrogen 2.893 N/A ASN 284.A ND2 THR 367.A OG1 no hydrogen 2.877 N/A ASN 284.A ND2 MET 371.A O no hydrogen 3.676 N/A ALA 285.A N VAL 281.A O no hydrogen 2.950 N/A LYS 286.A N ILE 282.A O no hydrogen 2.932 N/A ALA 287.A N LYS 283.A O no hydrogen 2.903 N/A LEU 288.A N ASN 284.A O no hydrogen 2.912 N/A ALA 289.A N ALA 285.A O no hydrogen 2.925 N/A ALA 291.A N ALA 287.A O no hydrogen 2.949 N/A LEU 292.A N LEU 288.A O no hydrogen 2.893 N/A TYR 293.A N ALA 289.A O no hydrogen 2.887 N/A GLU 294.A N GLN 290.A O no hydrogen 2.976 N/A ARG 295.A N LEU 292.A O no hydrogen 3.237 N/A ARG 295.A NE ALA 291.A O no hydrogen 2.815 N/A GLY 296.A N TYR 293.A O no hydrogen 3.340 N/A PHE 297.A N LEU 292.A O no hydrogen 3.281 N/A LEU 300.A N ILE 313.A O no hydrogen 3.306 N/A CYS 301.A SG GLU 142.A O no hydrogen 3.799 N/A HIS 303.A NE2 GLU 143.A OE1 no hydrogen 2.729 N/A ASP 305.A N GLU 302.A O no hydrogen 3.035 N/A SER 309.A OG PHE 170.A O no hydrogen 3.561 N/A HIS 310.A N HIS 310.A ND1 no hydrogen 2.944 N/A GLN 311.A N SER 309.A OG no hydrogen 2.988 N/A GLN 311.A NE2 SER 168.A O no hydrogen 3.035 N/A VAL 312.A N LEU 361.A O no hydrogen 2.892 N/A ILE 314.A N ILE 359.A O no hydrogen 2.894 N/A ASP 315.A N ASN 298.A O no hydrogen 2.495 N/A ILE 316.A N SER 357.A O no hydrogen 3.386 N/A GLU 317.A N GLU 317.A OE1 no hydrogen 2.707 N/A SER 318.A OG ASP 315.A OD2 no hydrogen 2.380 N/A SER 319.A N ILE 316.A O no hydrogen 2.894 N/A SER 319.A OG ILE 316.A O no hydrogen 2.504 N/A GLU 323.A N SER 319.A OG no hydrogen 3.142 N/A SER 325.A N GLU 328.A OE1 no hydrogen 2.695 N/A ALA 330.A N ALA 326.A O no hydrogen 2.550 N/A LYS 331.A N SER 327.A O no hydrogen 2.941 N/A TYR 333.A N LEU 329.A O no hydrogen 2.897 N/A TYR 333.A OH MET 383.A O no hydrogen 2.635 N/A GLU 334.A N ALA 330.A O no hydrogen 2.923 N/A GLU 335.A N LYS 331.A O no hydrogen 2.927 N/A ALA 336.A N TYR 333.A O no hydrogen 3.142 N/A ASN 337.A N GLU 334.A O no hydrogen 2.911 N/A ASN 337.A ND2 GLU 23.A O no hydrogen 3.229 N/A ILE 338.A N TYR 333.A O no hydrogen 2.939 N/A ILE 339.A N ILE 25.A O no hydrogen 2.932 N/A ASN 341.A ND2 LYS 342.A O no hydrogen 2.800 N/A ASN 341.A ND2 ASN 343.A OD1 no hydrogen 2.689 N/A ASN 343.A N GLY 358.A O no hydrogen 2.842 N/A ASP 348.A N LEU 345.A O no hydrogen 2.956 N/A ASN 351.A ND2 ASP 349.A OD1 no hydrogen 3.214 N/A SER 357.A N ASP 348.A OD2 no hydrogen 2.932 N/A SER 357.A OG ASP 348.A OD1 no hydrogen 2.448 N/A SER 357.A OG ASP 348.A OD2 no hydrogen 3.170 N/A ILE 359.A N ILE 314.A O no hydrogen 2.926 N/A ARG 360.A N ASN 341.A O no hydrogen 2.942 N/A ARG 360.A NE ASN 341.A OD1 no hydrogen 2.504 N/A ARG 360.A NH1 SER 168.A O no hydrogen 3.485 N/A ARG 360.A NH2 SER 30.A OG no hydrogen 2.894 N/A ARG 360.A NH2 ASN 341.A OD1 no hydrogen 2.993 N/A LEU 361.A N VAL 312.A O no hydrogen 2.929 N/A GLY 362.A N LEU 27.A O no hydrogen 2.642 N/A THR 363.A N HIS 310.A O no hydrogen 2.950 N/A THR 363.A OG1 VAL 281.A O no hydrogen 3.374 N/A THR 363.A OG1 HIS 310.A O no hydrogen 3.202 N/A CYS 366.A SG LYS 26.A O no hydrogen 4.033 N/A THR 367.A N THR 363.A O no hydrogen 3.120 N/A THR 367.A OG1 THR 363.A O no hydrogen 2.580 N/A ARG 368.A N GLN 364.A O no hydrogen 2.925 N/A ARG 368.A NH2 ILE 33.A O no hydrogen 3.401 N/A LEU 369.A N GLU 365.A O no hydrogen 2.925 N/A LEU 369.A N CYS 366.A O no hydrogen 2.979 N/A GLY 370.A N THR 367.A O no hydrogen 3.362 N/A MET 371.A N CYS 366.A O no hydrogen 3.163 N/A GLU 373.A N GLU 373.A OE1 no hydrogen 2.544 N/A MET 376.A N LYS 372.A O no hydrogen 3.004 N/A MET 376.A N GLU 373.A O no hydrogen 2.921 N/A GLU 377.A N GLU 373.A O no hydrogen 2.940 N/A GLU 378.A N LYS 374.A O no hydrogen 2.907 N/A ILE 379.A N GLU 375.A O no hydrogen 2.891 N/A ALA 380.A N MET 376.A O no hydrogen 2.910 N/A GLU 381.A N GLU 377.A O no hydrogen 2.959 N/A MET 383.A N ILE 379.A O no hydrogen 2.905 N/A LYS 384.A N ALA 380.A O no hydrogen 2.953 N/A ARG 385.A N PHE 382.A O no hydrogen 3.332 N/A ARG 385.A NH2 ASP 399.A OD1 no hydrogen 2.700 N/A ASP 389.A N LYS 384.A O no hydrogen 2.938 N/A LYS 390.A NZ ASP 321.A O no hydrogen 3.475 N/A GLU 391.A N ARG 385.A O no hydrogen 2.837 N/A LYS 392.A N GLU 391.A OE1 no hydrogen 3.378 N/A LYS 392.A NZ GLU 391.A OE1 no hydrogen 3.337 N/A ARG 397.A N GLU 394.A O no hydrogen 2.734 N/A GLU 398.A N GLU 394.A O no hydrogen 2.973 N/A PHE 403.A N ASP 399.A O no hydrogen 2.961 N/A ALA 404.A N VAL 400.A O no hydrogen 2.898 N/A LYS 405.A N LYS 401.A O no hydrogen 2.907 N/A GLU 406.A N GLU 402.A O no hydrogen 2.936 N/A SER 408.A OG ASP 418.A OD1 no hydrogen 2.639 N/A HIS 411.A N ARG 368.A O no hydrogen 2.498 N/A SER 413.A OG ASP 415.A O no hydrogen 2.856 N/A GLY 419.A N SER 408.A O no hydrogen 2.908 N/A ARG 424.A NH1 TYR 426.A OXT no hydrogen 2.497 N/A