Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4wjv_E.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 3.A N GLU 2.A OE1 no hydrogen 3.375 N/A GLY 4.A N ASN 271.A OD1 no hydrogen 3.035 N/A LEU 6.A N LYS 33.A O no hydrogen 3.278 N/A VAL 7.A N ASP 57.A OD1 no hydrogen 2.958 N/A ILE 8.A N THR 35.A O no hydrogen 2.908 N/A TRP 9.A N ILE 58.A O no hydrogen 3.070 N/A ILE 10.A N GLU 37.A O no hydrogen 3.061 N/A LYS 14.A N ASN 11.A O no hydrogen 3.083 N/A LYS 14.A NZ ASP 13.A OD1 no hydrogen 3.024 N/A LYS 14.A NZ ASP 13.A OD2 no hydrogen 2.874 N/A TYR 16.A N LYS 14.A O no hydrogen 2.933 N/A GLY 18.A N ASP 295.A OD2 no hydrogen 3.047 N/A LEU 19.A N GLY 15.A O no hydrogen 3.052 N/A ALA 20.A N TYR 16.A O no hydrogen 3.072 N/A GLY 23.A N LEU 19.A O no hydrogen 3.071 N/A LYS 24.A N ALA 20.A O no hydrogen 2.976 N/A LYS 24.A N GLU 21.A O no hydrogen 3.062 N/A LYS 25.A N GLU 21.A O no hydrogen 3.158 N/A PHE 26.A N VAL 22.A O no hydrogen 3.112 N/A GLU 27.A N GLY 23.A O no hydrogen 3.309 N/A LYS 28.A N LYS 24.A O no hydrogen 2.911 N/A ASP 29.A N LYS 25.A O no hydrogen 3.095 N/A ASP 29.A N PHE 26.A O no hydrogen 3.126 N/A THR 30.A N PHE 26.A O no hydrogen 3.088 N/A GLY 31.A N GLU 27.A O no hydrogen 2.793 N/A THR 35.A N LEU 6.A O no hydrogen 2.795 N/A GLU 37.A N ILE 8.A O no hydrogen 2.742 N/A GLU 43.A N GLU 43.A OE1 no hydrogen 2.633 N/A GLU 44.A N LYS 41.A O no hydrogen 3.089 N/A LYS 45.A N LYS 41.A O no hydrogen 2.683 N/A PHE 46.A N LEU 42.A O no hydrogen 2.881 N/A VAL 49.A N LYS 45.A O no hydrogen 3.029 N/A VAL 49.A N PHE 46.A O no hydrogen 2.987 N/A ALA 50.A N PHE 46.A O no hydrogen 2.586 N/A THR 52.A OG1 ALA 51.A O no hydrogen 2.326 N/A ASP 57.A N VAL 7.A O no hydrogen 2.937 N/A ILE 58.A N VAL 7.A O no hydrogen 3.145 N/A ILE 59.A N GLY 264.A O no hydrogen 3.016 N/A PHE 60.A N TRP 9.A O no hydrogen 2.734 N/A TRP 61.A N SER 262.A O no hydrogen 3.080 N/A HIS 63.A NE2 MET 329.A O no hydrogen 2.729 N/A PHE 66.A N HIS 63.A O no hydrogen 3.181 N/A TYR 69.A N ARG 65.A O no hydrogen 3.331 N/A TYR 69.A OH GLU 43.A O no hydrogen 2.812 N/A ALA 70.A N PHE 66.A O no hydrogen 2.779 N/A GLN 71.A N GLY 67.A O no hydrogen 3.005 N/A SER 72.A N TYR 69.A O no hydrogen 3.047 N/A GLY 73.A N ALA 70.A O no hydrogen 2.764 N/A LEU 74.A N TYR 69.A O no hydrogen 3.108 N/A ALA 76.A N ILE 265.A O no hydrogen 2.994 N/A ILE 78.A N LEU 102.A O no hydrogen 3.071 N/A GLN 85.A N ALA 81.A O no hydrogen 2.946 N/A ASP 86.A N ALA 82.A O no hydrogen 3.121 N/A LYS 87.A N PHE 84.A O no hydrogen 2.993 N/A TYR 89.A N ALA 302.A O no hydrogen 3.193 N/A THR 92.A N TYR 89.A O no hydrogen 3.177 N/A THR 92.A OG1 TYR 89.A O no hydrogen 2.684 N/A TRP 93.A N PRO 90.A O no hydrogen 3.048 N/A ASP 94.A N PRO 90.A O no hydrogen 3.262 N/A ARG 97.A N ASP 94.A O no hydrogen 3.404 N/A ARG 97.A NH1 ASP 94.A OD1 no hydrogen 3.149 N/A TYR 98.A N LYS 101.A O no hydrogen 3.064 N/A TYR 98.A OH GLN 71.A OE1 no hydrogen 2.226 N/A LYS 101.A N TYR 98.A O no hydrogen 3.268 N/A ILE 103.A N VAL 96.A O no hydrogen 3.104 N/A TYR 105.A N ALA 263.A O no hydrogen 2.675 N/A TYR 105.A OH GLU 280.A OE2 no hydrogen 2.751 N/A ILE 107.A N LEU 261.A O no hydrogen 2.601 N/A ALA 108.A N LEU 261.A O no hydrogen 3.249 N/A VAL 109.A N ALA 300.A O no hydrogen 2.561 N/A GLU 110.A N GLY 259.A O no hydrogen 2.542 N/A SER 113.A N ASN 226.A O no hydrogen 3.317 N/A LEU 114.A N THR 244.A O no hydrogen 2.893 N/A ILE 115.A N THR 224.A O no hydrogen 2.882 N/A TYR 116.A N GLY 242.A O no hydrogen 2.967 N/A ASN 117.A N ALA 222.A O no hydrogen 2.581 N/A LYS 118.A N ASN 240.A O no hydrogen 2.885 N/A ASP 119.A N ASN 117.A OD1 no hydrogen 3.050 N/A LEU 120.A N ASN 117.A OD1 no hydrogen 3.401 N/A LEU 121.A N ASN 117.A O no hydrogen 2.795 N/A THR 127.A N GLU 130.A OE2 no hydrogen 3.361 N/A THR 127.A OG1 GLU 130.A OE2 no hydrogen 3.161 N/A TRP 128.A N THR 248.A O no hydrogen 2.822 N/A GLU 129.A N GLU 129.A OE1 no hydrogen 2.516 N/A GLU 130.A N THR 127.A O no hydrogen 3.310 N/A ILE 131.A N TRP 128.A O no hydrogen 3.193 N/A LEU 134.A N GLU 130.A O no hydrogen 2.685 N/A ASP 135.A N ILE 131.A O no hydrogen 2.711 N/A LYS 136.A N PRO 132.A O no hydrogen 3.410 N/A LYS 139.A N ASP 135.A O no hydrogen 2.812 N/A LYS 139.A NZ ASP 135.A OD2 no hydrogen 2.680 N/A ALA 140.A N LYS 136.A O no hydrogen 3.295 N/A LYS 141.A N LEU 138.A O no hydrogen 3.008 N/A GLY 142.A N LYS 139.A O no hydrogen 3.317 N/A LYS 143.A N LEU 138.A O no hydrogen 2.789 N/A SER 144.A N GLU 220.A O no hydrogen 3.261 N/A ALA 145.A N ASP 135.A OD1 no hydrogen 2.898 N/A MET 147.A N MET 223.A O no hydrogen 3.172 N/A LEU 150.A N THR 207.A O no hydrogen 3.137 N/A GLN 151.A N ASN 149.A OD1 no hydrogen 2.767 N/A GLN 151.A NE2 ALA 205.A O no hydrogen 2.958 N/A GLN 151.A NE2 THR 207.A O no hydrogen 3.243 N/A TYR 154.A OH PHE 257.A O no hydrogen 3.395 N/A PHE 155.A N GLU 152.A O no hydrogen 3.340 N/A THR 156.A OG1 PRO 153.A O no hydrogen 3.388 N/A TRP 157.A N PRO 153.A O no hydrogen 2.868 N/A LEU 159.A N THR 156.A O no hydrogen 3.356 N/A ILE 160.A N THR 156.A O no hydrogen 3.460 N/A ALA 161.A N TRP 157.A O no hydrogen 2.867 N/A ALA 162.A N LEU 159.A O no hydrogen 3.326 N/A TYR 166.A N GLY 181.A O no hydrogen 2.909 N/A TYR 166.A OH ASP 179.A OD1 no hydrogen 2.665 N/A LYS 169.A N ASP 179.A O no hydrogen 3.173 N/A GLU 171.A N LYS 174.A O no hydrogen 2.844 N/A ASP 176.A N LYS 169.A O no hydrogen 2.990 N/A ASP 179.A N ASP 176.A O no hydrogen 3.063 N/A ASN 184.A ND2 GLY 164.A O no hydrogen 3.340 N/A GLY 186.A N ASN 184.A OD1 no hydrogen 2.860 N/A ALA 187.A N ASN 184.A OD1 no hydrogen 3.142 N/A LYS 188.A N ASN 184.A O no hydrogen 2.966 N/A LYS 188.A NZ ASP 357.A OD2 no hydrogen 3.118 N/A ALA 189.A N ALA 185.A O no hydrogen 3.005 N/A GLY 190.A N GLY 186.A O no hydrogen 3.264 N/A LEU 191.A N ALA 187.A O no hydrogen 3.234 N/A THR 192.A N LYS 188.A O no hydrogen 3.163 N/A THR 192.A OG1 LYS 188.A O no hydrogen 2.604 N/A LEU 194.A N GLY 190.A O no hydrogen 3.256 N/A VAL 195.A N LEU 191.A O no hydrogen 3.047 N/A ASP 196.A N THR 192.A O no hydrogen 2.821 N/A LEU 197.A N PHE 193.A O no hydrogen 3.088 N/A ILE 198.A N LEU 194.A O no hydrogen 3.182 N/A LYS 199.A N VAL 195.A O no hydrogen 2.758 N/A ASN 200.A N ASP 196.A O no hydrogen 3.142 N/A ASN 200.A ND2 ASP 196.A O no hydrogen 2.316 N/A LYS 201.A N ILE 198.A O no hydrogen 3.153 N/A HIS 202.A N LEU 197.A O no hydrogen 2.717 N/A HIS 202.A ND1 ASP 135.A OD2 no hydrogen 2.958 N/A MET 203.A N LEU 197.A O no hydrogen 3.137 N/A ASN 204.A ND2 ASP 206.A OD2 no hydrogen 3.558 N/A THR 207.A N ASN 204.A O no hydrogen 3.228 N/A THR 207.A OG1 ASN 204.A O no hydrogen 2.969 N/A SER 210.A OG ASP 208.A OD1 no hydrogen 3.069 N/A ILE 211.A N ASP 208.A OD1 no hydrogen 2.778 N/A ALA 212.A N ASP 208.A O no hydrogen 3.319 N/A GLU 213.A N TYR 209.A O no hydrogen 2.937 N/A ALA 214.A N SER 210.A O no hydrogen 3.075 N/A ALA 215.A N ILE 211.A O no hydrogen 3.177 N/A PHE 216.A N ALA 212.A O no hydrogen 3.201 N/A ASN 217.A N GLU 213.A O no hydrogen 3.195 N/A LYS 218.A N ALA 214.A O no hydrogen 3.028 N/A GLY 219.A N PHE 216.A O no hydrogen 3.084 N/A GLU 220.A N ALA 215.A O no hydrogen 2.792 N/A THR 221.A OG1 SER 144.A O no hydrogen 3.194 N/A THR 221.A OG1 SER 144.A OG no hydrogen 3.394 N/A THR 221.A OG1 MET 223.A O no hydrogen 3.400 N/A ALA 222.A N SER 144.A O no hydrogen 3.034 N/A MET 223.A N ALA 145.A O no hydrogen 2.903 N/A THR 224.A N ILE 115.A O no hydrogen 2.831 N/A THR 224.A OG1 MET 147.A O no hydrogen 2.750 N/A ASN 226.A ND2 TYR 209.A OH no hydrogen 3.179 N/A GLY 227.A N ASN 226.A OD1 no hydrogen 2.734 N/A ALA 230.A N GLY 227.A O no hydrogen 3.008 N/A TRP 231.A N PRO 228.A O no hydrogen 3.083 N/A SER 232.A OG ASN 233.A OD1 no hydrogen 2.650 N/A ASP 235.A N TRP 231.A O no hydrogen 3.178 N/A ASP 235.A N SER 232.A O no hydrogen 3.047 N/A THR 236.A N SER 232.A O no hydrogen 3.320 N/A THR 236.A OG1 ASN 233.A O no hydrogen 3.001 N/A SER 237.A N ILE 234.A O no hydrogen 3.154 N/A SER 237.A OG ILE 234.A O no hydrogen 2.528 N/A VAL 239.A N SER 237.A OG no hydrogen 3.425 N/A TYR 241.A OH ASP 235.A OD1 no hydrogen 2.919 N/A GLY 242.A N TYR 116.A O no hydrogen 2.959 N/A THR 244.A N LEU 114.A O no hydrogen 2.808 N/A LEU 246.A N ASN 322.A OD1 no hydrogen 3.007 N/A THR 248.A N LYS 126.A O no hydrogen 2.865 N/A THR 248.A OG1 LYS 126.A O no hydrogen 3.335 N/A PHE 249.A N GLN 252.A O no hydrogen 2.785 N/A LYS 250.A N GLU 129.A OE2 no hydrogen 3.229 N/A GLN 252.A N PHE 249.A O no hydrogen 3.071 N/A SER 254.A OG PRO 247.A O no hydrogen 2.703 N/A LYS 255.A N PRO 158.A O no hydrogen 3.370 N/A LYS 255.A NZ ALA 162.A O no hydrogen 3.339 N/A LYS 255.A NZ PRO 253.A O no hydrogen 3.335 N/A VAL 258.A N GLU 327.A O no hydrogen 2.723 N/A GLY 259.A N GLU 110.A O no hydrogen 3.002 N/A VAL 260.A N HIS 63.A ND1 no hydrogen 2.983 N/A LEU 261.A N ALA 108.A O no hydrogen 2.618 N/A SER 262.A N TRP 61.A O no hydrogen 2.747 N/A SER 262.A OG VAL 260.A O no hydrogen 2.735 N/A ALA 263.A N TYR 105.A O no hydrogen 2.757 N/A GLY 264.A N ILE 59.A O no hydrogen 3.112 N/A ASN 266.A N ASP 57.A O no hydrogen 2.680 N/A ASN 266.A ND2 ASP 54.A O no hydrogen 3.322 N/A ASN 266.A ND2 PRO 56.A O no hydrogen 2.882 N/A ALA 267.A N LEU 74.A O no hydrogen 3.225 N/A ALA 268.A N ASN 266.A OD1 no hydrogen 2.920 N/A SER 269.A N ASN 266.A O no hydrogen 3.188 N/A SER 269.A OG ASP 57.A OD2 no hydrogen 2.309 N/A ASN 271.A N SER 269.A OG no hydrogen 3.130 N/A ASN 271.A ND2 GLU 2.A O no hydrogen 3.489 N/A ASN 271.A ND2 ASP 57.A OD2 no hydrogen 3.168 N/A LYS 272.A NZ ASN 266.A O no hydrogen 3.519 N/A LYS 272.A NZ ALA 267.A O no hydrogen 3.036 N/A LYS 272.A NZ SER 269.A O no hydrogen 2.358 N/A ALA 275.A N ASN 271.A O no hydrogen 2.917 N/A LYS 276.A N LYS 272.A O no hydrogen 2.870 N/A GLU 277.A N GLU 273.A O no hydrogen 2.855 N/A PHE 278.A N LEU 274.A O no hydrogen 2.715 N/A LEU 279.A N ALA 275.A O no hydrogen 2.979 N/A GLU 280.A N LYS 276.A O no hydrogen 3.327 N/A ASN 281.A N GLU 277.A O no hydrogen 3.005 N/A TYR 282.A N PHE 278.A O no hydrogen 3.022 N/A TYR 282.A OH ASP 29.A OD1 no hydrogen 3.095 N/A LEU 283.A N PHE 278.A O no hydrogen 3.151 N/A LEU 284.A N LEU 279.A O no hydrogen 2.821 N/A THR 285.A OG1 TYR 282.A O no hydrogen 2.891 N/A THR 285.A OG1 GLU 287.A OE1 no hydrogen 3.520 N/A GLU 287.A N GLU 287.A OE1 no hydrogen 2.556 N/A GLY 288.A N THR 285.A OG1 no hydrogen 3.153 N/A LEU 289.A N THR 285.A O no hydrogen 3.136 N/A ALA 291.A N GLU 287.A O no hydrogen 2.960 N/A VAL 292.A N GLY 288.A O no hydrogen 3.263 N/A ASN 293.A N LEU 289.A O no hydrogen 2.701 N/A LYS 294.A N GLU 290.A O no hydrogen 2.961 N/A ASP 295.A N VAL 292.A O no hydrogen 2.935 N/A LYS 296.A N VAL 292.A O no hydrogen 3.068 N/A LEU 298.A N ASN 293.A OD1 no hydrogen 2.908 N/A ALA 302.A N ILE 107.A O no hydrogen 2.909 N/A LYS 304.A N LYS 87.A O no hydrogen 2.756 N/A LYS 304.A NZ ASP 86.A O no hydrogen 3.242 N/A SER 305.A OG ASP 286.A OD1 no hydrogen 2.727 N/A GLU 307.A N LEU 303.A O no hydrogen 2.985 N/A GLU 308.A N LYS 304.A O no hydrogen 3.156 N/A GLU 309.A N TYR 306.A O no hydrogen 3.074 N/A LEU 310.A N TYR 306.A O no hydrogen 3.222 N/A ALA 311.A N GLU 307.A O no hydrogen 2.933 N/A LYS 312.A N GLU 309.A O no hydrogen 3.353 N/A ASP 313.A N LEU 310.A O no hydrogen 3.051 N/A ARG 315.A N ASP 313.A OD1 no hydrogen 3.008 N/A ARG 315.A NE ASP 313.A OD1 no hydrogen 3.173 N/A ARG 315.A NE ASP 313.A OD2 no hydrogen 3.165 N/A ARG 315.A NH2 ASP 313.A OD2 no hydrogen 2.822 N/A ALA 317.A N ASP 313.A O no hydrogen 2.876 N/A ALA 318.A N PRO 314.A O no hydrogen 2.994 N/A THR 319.A N ARG 315.A O no hydrogen 2.954 N/A THR 319.A OG1 ARG 315.A O no hydrogen 3.096 N/A MET 320.A N ILE 316.A O no hydrogen 2.988 N/A GLU 321.A N ALA 317.A O no hydrogen 3.303 N/A ASN 322.A N ALA 318.A O no hydrogen 3.165 N/A ASN 322.A ND2 SER 113.A OG no hydrogen 2.914 N/A ASN 322.A ND2 THR 244.A O no hydrogen 3.489 N/A ALA 323.A N THR 319.A O no hydrogen 2.970 N/A GLN 324.A N MET 320.A O no hydrogen 2.781 N/A LYS 325.A N GLU 321.A O no hydrogen 3.265 N/A GLY 326.A N ALA 323.A O no hydrogen 3.376 N/A GLU 327.A N PRO 256.A O no hydrogen 3.116 N/A MET 329.A N VAL 258.A O no hydrogen 3.289 N/A ASN 331.A ND2 ARG 97.A O no hydrogen 2.999 N/A MET 335.A N ILE 332.A O no hydrogen 3.100 N/A PHE 338.A N GLN 334.A O no hydrogen 2.976 N/A TRP 339.A N MET 335.A O no hydrogen 3.019 N/A TYR 340.A N SER 336.A O no hydrogen 3.196 N/A TYR 340.A OH GLU 44.A OE2 no hydrogen 2.899 N/A ALA 341.A N ALA 337.A O no hydrogen 3.046 N/A VAL 342.A N PHE 338.A O no hydrogen 3.025 N/A ARG 343.A N TRP 339.A O no hydrogen 2.898 N/A THR 344.A N TYR 340.A O no hydrogen 3.237 N/A THR 344.A OG1 TYR 340.A O no hydrogen 3.007 N/A ALA 345.A N ALA 341.A O no hydrogen 3.198 N/A VAL 346.A N VAL 342.A O no hydrogen 2.889 N/A ILE 347.A N ARG 343.A O no hydrogen 3.009 N/A ASN 348.A N THR 344.A O no hydrogen 2.840 N/A ASN 348.A ND2 GLN 354.A OE1 no hydrogen 3.283 N/A ALA 349.A N ALA 345.A O no hydrogen 2.859 N/A ALA 350.A N VAL 346.A O no hydrogen 3.132 N/A SER 351.A N ILE 347.A O no hydrogen 3.012 N/A SER 351.A OG ILE 347.A O no hydrogen 3.302 N/A SER 351.A OG ASN 348.A O no hydrogen 3.335 N/A GLY 352.A N ALA 349.A O no hydrogen 3.294 N/A ARG 353.A N SER 351.A OG no hydrogen 3.287 N/A GLN 354.A N ASN 348.A O no hydrogen 3.060 N/A ALA 359.A N THR 355.A O no hydrogen 2.638 N/A LEU 360.A N VAL 356.A O no hydrogen 3.063 N/A ALA 361.A N ASP 357.A O no hydrogen 3.112 N/A ALA 362.A N ALA 358.A O no hydrogen 3.400 N/A ALA 363.A N ALA 359.A O no hydrogen 3.066 N/A GLN 364.A N LEU 360.A O no hydrogen 2.909 N/A THR 365.A N ALA 361.A O no hydrogen 3.392 N/A THR 365.A OG1 ALA 361.A O no hydrogen 3.020 N/A ASN 366.A N ALA 362.A O no hydrogen 3.189 N/A ALA 367.A N ALA 363.A O no hydrogen 2.982 N/A