Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4x7d_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 2.A NZ GLU 241.A O no hydrogen 3.220 N/A SER 5.A OG TYR 237.A OH no hydrogen 2.952 N/A THR 10.A N GLU 13.A OE1 no hydrogen 2.982 N/A GLU 13.A N THR 10.A O no hydrogen 3.211 N/A GLU 13.A N THR 10.A OG1 no hydrogen 3.065 N/A MET 14.A N VAL 11.A O no hydrogen 2.876 N/A THR 15.A N GLU 233.A OE1 no hydrogen 2.733 N/A THR 15.A OG1 GLU 233.A OE2 no hydrogen 2.693 N/A ASN 16.A N ILE 21.A O no hydrogen 2.891 N/A ASN 16.A ND2 SER 213.A OG no hydrogen 2.919 N/A ASN 16.A ND2 LEU 226.A O no hydrogen 3.264 N/A SER 17.A OG LEU 230.A O no hydrogen 2.757 N/A ARG 18.A N ASN 16.A OD1 no hydrogen 2.856 N/A ARG 18.A NE ASP 102.A OD1 no hydrogen 3.088 N/A ARG 18.A NE ASP 102.A OD2 no hydrogen 3.209 N/A ARG 18.A NH1 GLN 179.A OE1 no hydrogen 3.193 N/A ARG 18.A NH1 ASP 227.A O no hydrogen 2.575 N/A ARG 18.A NH2 ASP 102.A OD1 no hydrogen 3.127 N/A ARG 18.A NH2 GLN 179.A O no hydrogen 2.888 N/A ILE 21.A N PHE 19.A O no hydrogen 2.800 N/A LEU 23.A N MET 14.A O no hydrogen 2.786 N/A GLU 24.A N ARG 212.A O no hydrogen 2.780 N/A LYS 25.A N ARG 212.A O no hydrogen 3.050 N/A PHE 27.A N PHE 210.A O no hydrogen 2.953 N/A THR 28.A N HIS 282.A O no hydrogen 3.029 N/A THR 28.A OG1 LEU 208.A O no hydrogen 2.763 N/A GLN 37.A NE2 ALA 196.A O no hydrogen 2.863 N/A GLN 39.A N ASP 102.A OD2 no hydrogen 2.827 N/A GLN 39.A NE2 GLN 37.A O no hydrogen 3.055 N/A GLN 39.A NE2 ALA 196.A O no hydrogen 3.112 N/A ASN 40.A N ASP 102.A OD2 no hydrogen 2.992 N/A ASN 40.A ND2 THR 100.A O no hydrogen 2.784 N/A ARG 42.A N THR 53.A OG1 no hydrogen 2.851 N/A ARG 42.A NH1 PRO 38.A O no hydrogen 2.868 N/A ARG 42.A NH1 PRO 197.A O no hydrogen 2.885 N/A ARG 42.A NH2 PRO 197.A O no hydrogen 2.905 N/A CYS 43.A SG THR 44.A O no hydrogen 3.279 N/A CYS 43.A SG VAL 48.A O no hydrogen 3.902 N/A CYS 43.A SG VAL 235.A O no hydrogen 3.957 N/A THR 44.A N VAL 48.A O no hydrogen 2.982 N/A THR 44.A OG1 ASP 46.A OD1 no hydrogen 2.553 N/A THR 45.A N LYS 270.A O no hydrogen 2.898 N/A GLY 47.A N THR 44.A O no hydrogen 2.740 N/A VAL 48.A N THR 44.A OG1 no hydrogen 2.827 N/A LEU 50.A N ARG 42.A O no hydrogen 2.901 N/A THR 52.A N GLN 39.A O no hydrogen 2.830 N/A THR 52.A OG1 ASN 40.A OD1 no hydrogen 2.977 N/A THR 53.A N LEU 50.A O no hydrogen 3.073 N/A THR 53.A OG1 GLN 39.A O no hydrogen 2.984 N/A THR 53.A OG1 ARG 42.A O no hydrogen 3.216 N/A THR 53.A OG1 LEU 50.A O no hydrogen 3.034 N/A GLN 54.A NE2 SER 56.A O no hydrogen 2.658 N/A SER 56.A N GLN 54.A OE1 no hydrogen 3.222 N/A SER 56.A OG GLN 54.A OE1 no hydrogen 3.410 N/A SER 56.A OG ASN 59.A OD1 no hydrogen 2.206 N/A ASN 59.A N SER 56.A O no hydrogen 3.241 N/A ASN 59.A N SER 56.A OG no hydrogen 3.263 N/A ILE 60.A N PRO 57.A O no hydrogen 3.386 N/A CYS 61.A N GLY 99.A O no hydrogen 2.676 N/A CYS 61.A SG ARG 18.A O no hydrogen 3.725 N/A THR 62.A N ASN 59.A O no hydrogen 3.426 N/A THR 62.A OG1 ASN 59.A O no hydrogen 3.005 N/A PHE 63.A N PHE 160.A O no hydrogen 3.398 N/A GLY 65.A N THR 158.A O no hydrogen 3.088 N/A ASP 66.A N ASN 79.A O no hydrogen 3.329 N/A THR 68.A N THR 77.A O no hydrogen 2.784 N/A HIS 69.A NE2 SER 73.A O no hydrogen 2.539 N/A ILE 70.A N ASN 75.A O no hydrogen 3.062 N/A SER 73.A N ILE 70.A O no hydrogen 3.077 N/A SER 73.A OG ILE 70.A O no hydrogen 2.409 N/A ASN 75.A N SER 73.A OG no hydrogen 3.289 N/A TYR 76.A N PHE 144.A O no hydrogen 2.832 N/A THR 77.A N THR 68.A O no hydrogen 2.886 N/A MET 78.A N VAL 142.A O no hydrogen 2.836 N/A ASN 79.A N ASP 66.A O no hydrogen 2.853 N/A LEU 80.A N GLY 140.A O no hydrogen 2.755 N/A ALA 81.A N ARG 64.A O no hydrogen 2.716 N/A SER 82.A N ASN 86.A O no hydrogen 2.922 N/A SER 82.A OG ASN 84.A OD1 no hydrogen 2.643 N/A SER 82.A OG ASN 86.A O no hydrogen 3.263 N/A TRP 85.A N SER 82.A O no hydrogen 2.839 N/A ASN 86.A N ASN 84.A OD1 no hydrogen 3.067 N/A TYR 88.A OH LYS 138.A O no hydrogen 2.734 N/A THR 91.A N ASP 89.A OD1 no hydrogen 2.933 N/A THR 91.A OG1 ASP 89.A OD1 no hydrogen 2.707 N/A THR 91.A OG1 ASP 89.A OD2 no hydrogen 3.188 N/A GLU 92.A N ASP 89.A O no hydrogen 3.341 N/A ILE 94.A N GLU 92.A O no hydrogen 2.702 N/A GLY 99.A N THR 52.A O no hydrogen 2.848 N/A THR 100.A N PRO 97.A O no hydrogen 3.098 N/A THR 100.A OG1 PRO 97.A O no hydrogen 2.602 N/A VAL 104.A N VAL 181.A O no hydrogen 2.949 N/A GLY 105.A N THR 130.A OG1 no hydrogen 2.832 N/A LYS 106.A NZ ASP 168.A OD1 no hydrogen 2.661 N/A LYS 106.A NZ GLU 176.A OE1 no hydrogen 3.269 N/A LYS 106.A NZ GLU 176.A OE2 no hydrogen 2.951 N/A ILE 107.A N VAL 128.A O no hydrogen 2.769 N/A GLN 108.A N GLY 164.A O no hydrogen 2.987 N/A GLN 108.A NE2 THR 127.A OG1 no hydrogen 3.087 N/A GLY 109.A N ALA 126.A O no hydrogen 2.750 N/A VAL 110.A N THR 161.A O no hydrogen 2.872 N/A LEU 111.A N HIS 124.A O no hydrogen 2.896 N/A THR 112.A N LYS 159.A O no hydrogen 2.730 N/A THR 112.A OG1 LYS 159.A O no hydrogen 3.513 N/A GLN 113.A N ARG 122.A O no hydrogen 2.821 N/A GLN 113.A NE2 GLU 153.A O no hydrogen 2.836 N/A GLN 113.A NE2 THR 158.A OG1 no hydrogen 3.177 N/A THR 114.A N ASN 157.A O no hydrogen 3.294 N/A THR 115.A N SER 120.A O no hydrogen 2.832 N/A THR 115.A OG1 GLU 153.A OE1 no hydrogen 2.804 N/A THR 115.A OG1 GLU 153.A OE2 no hydrogen 3.409 N/A ARG 116.A N GLN 156.A OE1 no hydrogen 3.043 N/A ARG 116.A NH2 ASN 155.A O no hydrogen 2.888 N/A GLY 119.A N THR 115.A O no hydrogen 2.779 N/A SER 120.A N ASP 118.A OD1 no hydrogen 3.249 N/A SER 120.A OG ASP 118.A OD1 no hydrogen 2.768 N/A SER 120.A OG ASP 118.A OD2 no hydrogen 3.457 N/A ARG 122.A N GLN 113.A O no hydrogen 2.927 N/A ARG 122.A NH1 GLN 113.A OE1 no hydrogen 2.548 N/A ARG 122.A NH1 THR 115.A OG1 no hydrogen 3.055 N/A ARG 122.A NH2 THR 115.A OG1 no hydrogen 2.731 N/A HIS 124.A N LEU 111.A O no hydrogen 2.892 N/A HIS 124.A NE2 ASP 151.A OD2 no hydrogen 2.578 N/A ALA 126.A N GLY 109.A O no hydrogen 2.934 N/A THR 127.A N GLU 145.A O no hydrogen 2.814 N/A VAL 128.A N ILE 107.A O no hydrogen 2.838 N/A THR 130.A N GLY 105.A O no hydrogen 2.989 N/A THR 130.A OG1 PHE 103.A O no hydrogen 2.724 N/A THR 130.A OG1 GLY 105.A O no hydrogen 3.120 N/A SER 132.A N TYR 129.A O no hydrogen 3.120 N/A SER 132.A OG TYR 129.A O no hydrogen 3.221 N/A PHE 135.A N SER 132.A O no hydrogen 3.008 N/A ALA 136.A N ARG 141.A O no hydrogen 2.865 N/A LYS 138.A N TYR 185.A O no hydrogen 2.918 N/A LYS 138.A NZ PRO 90.A O no hydrogen 2.830 N/A LYS 138.A NZ GLU 92.A O no hydrogen 2.775 N/A LYS 138.A NZ ILE 94.A O no hydrogen 3.063 N/A LEU 139.A N ALA 136.A O no hydrogen 2.867 N/A GLY 140.A N PRO 137.A O no hydrogen 2.790 N/A ARG 141.A N ALA 136.A O no hydrogen 3.258 N/A VAL 142.A N MET 78.A O no hydrogen 3.294 N/A PHE 144.A N TYR 76.A O no hydrogen 2.724 N/A GLU 145.A N THR 127.A O no hydrogen 2.800 N/A THR 146.A N ARG 74.A O no hydrogen 2.777 N/A THR 146.A OG1 ARG 74.A O no hydrogen 2.749 N/A THR 148.A N THR 146.A OG1 no hydrogen 3.193 N/A ARG 150.A N THR 148.A OG1 no hydrogen 2.969 N/A ASP 151.A N THR 148.A OG1 no hydrogen 2.840 N/A GLU 153.A N GLN 113.A OE1 no hydrogen 2.919 N/A THR 158.A N GLY 65.A O no hydrogen 2.790 N/A THR 158.A OG1 GLN 156.A O no hydrogen 2.691 N/A LYS 159.A N THR 112.A O no hydrogen 2.868 N/A LYS 159.A NZ THR 161.A OG1 no hydrogen 3.386 N/A PHE 160.A N PHE 63.A O no hydrogen 2.882 N/A THR 161.A N VAL 110.A O no hydrogen 2.888 N/A VAL 163.A N GLN 108.A O no hydrogen 2.828 N/A GLY 164.A N GLN 108.A O no hydrogen 3.189 N/A VAL 165.A N PRO 216.A O no hydrogen 2.818 N/A ILE 166.A N LYS 106.A O no hydrogen 3.109 N/A GLN 167.A N SER 219.A O no hydrogen 3.072 N/A GLN 167.A NE2 THR 171.A OG1 no hydrogen 3.008 N/A ASP 168.A N GLU 176.A OE2 no hydrogen 3.044 N/A THR 171.A N ASP 168.A O no hydrogen 3.472 N/A THR 171.A OG1 ASP 168.A O no hydrogen 3.198 N/A THR 171.A OG1 GLU 176.A OE2 no hydrogen 2.477 N/A ARG 174.A N TYR 221.A O no hydrogen 2.760 N/A ASN 175.A N THR 172.A O no hydrogen 3.117 N/A GLN 178.A N VAL 104.A O no hydrogen 2.896 N/A GLN 179.A NE2 ASP 227.A OD2 no hydrogen 3.076 N/A VAL 181.A N GLN 178.A O no hydrogen 3.119 N/A TYR 185.A N ASN 192.A OD1 no hydrogen 2.941 N/A GLY 187.A N SER 184.A O no hydrogen 2.902 N/A ARG 188.A N ALA 133.A O no hydrogen 3.234 N/A THR 190.A OG1 GLY 187.A O no hydrogen 2.637 N/A ASN 192.A ND2 PRO 183.A O no hydrogen 2.781 N/A ALA 196.A N GLN 39.A OE1 no hydrogen 2.677 N/A VAL 199.A N VAL 36.A O no hydrogen 2.889 N/A GLN 207.A N VAL 276.A O no hydrogen 2.847 N/A GLN 207.A NE2 THR 28.A OG1 no hydrogen 3.002 N/A GLN 207.A NE2 GLY 280.A O no hydrogen 3.071 N/A LEU 209.A N VAL 274.A O no hydrogen 2.853 N/A PHE 210.A N PHE 27.A O no hydrogen 2.634 N/A PHE 211.A N CYS 228.A O no hydrogen 2.992 N/A ARG 212.A N LYS 25.A O no hydrogen 2.743 N/A ARG 212.A NE ASP 227.A OD1 no hydrogen 2.771 N/A ARG 212.A NH2 ASP 227.A OD1 no hydrogen 3.444 N/A ARG 212.A NH2 ASP 227.A OD2 no hydrogen 2.709 N/A SER 213.A N LEU 226.A O no hydrogen 2.972 N/A SER 213.A OG PRO 22.A O no hydrogen 2.776 N/A THR 214.A N GLU 24.A OE2 no hydrogen 2.779 N/A THR 214.A OG1 GLU 24.A OE1 no hydrogen 2.898 N/A MET 215.A N MET 224.A O no hydrogen 2.820 N/A CYS 218.A N VAL 165.A O no hydrogen 2.890 N/A TYR 221.A N GLN 167.A OE1 no hydrogen 2.946 N/A ASN 223.A N GLU 176.A O no hydrogen 2.824 N/A ASP 225.A N ASN 223.A OD1 no hydrogen 2.957 N/A LEU 226.A N SER 213.A O no hydrogen 3.042 N/A ASP 227.A N GLN 179.A OE1 no hydrogen 2.792 N/A CYS 228.A N PHE 211.A O no hydrogen 3.003 N/A CYS 228.A SG PHE 211.A O no hydrogen 3.610 N/A CYS 228.A SG LEU 230.A O no hydrogen 3.352 N/A GLN 232.A N THR 15.A O no hydrogen 2.951 N/A GLN 232.A NE2 GLN 54.A O no hydrogen 3.094 N/A GLN 232.A NE2 LEU 55.A O no hydrogen 2.427 N/A GLU 233.A N GLU 233.A OE1 no hydrogen 2.619 N/A VAL 235.A N PRO 231.A O no hydrogen 3.245 N/A GLN 236.A N GLN 232.A O no hydrogen 3.013 N/A GLN 236.A NE2 LEU 55.A O no hydrogen 3.086 N/A TYR 237.A N GLU 233.A O no hydrogen 2.877 N/A TYR 237.A OH SER 5.A OG no hydrogen 2.952 N/A PHE 238.A N TRP 234.A O no hydrogen 2.773 N/A TYR 239.A N VAL 235.A O no hydrogen 3.055 N/A GLN 240.A N GLN 236.A O no hydrogen 3.051 N/A GLU 241.A N TYR 237.A O no hydrogen 2.751 N/A ALA 242.A N PHE 238.A O no hydrogen 2.853 N/A SER 247.A OG VAL 298.A O no hydrogen 2.677 N/A VAL 249.A N SER 247.A OG no hydrogen 3.412 N/A ALA 250.A N LEU 268.A O no hydrogen 2.778 N/A LEU 251.A N SER 296.A O no hydrogen 2.731 N/A LEU 252.A N CYS 266.A O no hydrogen 2.941 N/A ARG 253.A N ARG 293.A O no hydrogen 2.766 N/A ARG 253.A NE GLU 265.A OE1 no hydrogen 2.886 N/A ARG 253.A NH1 ASP 295.A OD2 no hydrogen 2.826 N/A ARG 253.A NH2 GLU 265.A OE1 no hydrogen 3.206 N/A ARG 253.A NH2 TYR 302.A OH no hydrogen 3.143 N/A PHE 254.A N PHE 264.A O no hydrogen 2.833 N/A VAL 255.A N TYR 291.A O no hydrogen 2.816 N/A ASN 256.A N ARG 261.A O no hydrogen 2.952 N/A ASP 258.A N ASN 256.A OD1 no hydrogen 3.109 N/A GLY 260.A N ASN 256.A O no hydrogen 2.697 N/A ARG 261.A N THR 259.A OG1 no hydrogen 3.180 N/A LEU 263.A N PHE 254.A O no hydrogen 2.704 N/A CYS 266.A N LEU 252.A O no hydrogen 2.978 N/A LYS 267.A N THR 275.A O no hydrogen 2.963 N/A LYS 267.A NZ ASN 299.A O no hydrogen 3.519 N/A LYS 267.A NZ TYR 302.A O no hydrogen 2.761 N/A LEU 268.A N ALA 250.A O no hydrogen 2.763 N/A HIS 269.A N TYR 273.A O no hydrogen 2.742 N/A HIS 269.A NE2 THR 275.A OG1 no hydrogen 2.998 N/A LYS 270.A N ASP 248.A O no hydrogen 2.852 N/A GLY 272.A N HIS 269.A O no hydrogen 2.878 N/A THR 275.A N LYS 267.A O no hydrogen 2.929 N/A THR 275.A OG1 HIS 269.A NE2 no hydrogen 2.998 N/A VAL 276.A N GLN 207.A O no hydrogen 2.848 N/A GLY 280.A N GLN 207.A OE1 no hydrogen 2.739 N/A HIS 282.A N THR 28.A O no hydrogen 2.724 N/A LEU 284.A N LEU 26.A O no hydrogen 3.099 N/A ASN 289.A ND2 ASP 258.A OD1 no hydrogen 3.323 N/A GLY 290.A N PRO 287.A O no hydrogen 3.144 N/A TYR 291.A N VAL 255.A O no hydrogen 3.023 N/A ARG 293.A N ARG 253.A O no hydrogen 2.803 N/A ARG 293.A NE ASP 295.A OD1 no hydrogen 2.684 N/A ARG 293.A NH2 ASP 295.A OD1 no hydrogen 3.425 N/A ARG 293.A NH2 ASP 295.A OD2 no hydrogen 2.868 N/A ASP 295.A N LEU 251.A O no hydrogen 2.795 N/A SER 296.A OG ASP 295.A O no hydrogen 2.627 N/A VAL 298.A N VAL 249.A O no hydrogen 2.798 N/A PHE 301.A N ASN 299.A OD1 no hydrogen 2.952 N/A TYR 302.A N ASN 299.A O no hydrogen 3.218 N/A TYR 302.A OH GLU 265.A OE1 no hydrogen 2.620 N/A TYR 302.A OH GLU 265.A OE2 no hydrogen 3.099 N/A ALA 305.A N GLU 265.A OE2 no hydrogen 2.774 N/A MET 307.A N ALA 277.A O no hydrogen 2.827 N/A