Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4x7f_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 4.A OG1 HIS 237.A NE2 no hydrogen 2.831 N/A THR 9.A N GLU 12.A OE1 no hydrogen 3.023 N/A GLU 12.A N THR 9.A O no hydrogen 2.766 N/A LEU 13.A N LEU 10.A O no hydrogen 3.240 N/A THR 14.A N GLU 233.A OE1 no hydrogen 2.774 N/A THR 14.A OG1 GLU 233.A OE1 no hydrogen 3.345 N/A THR 14.A OG1 GLU 233.A OE2 no hydrogen 2.824 N/A ASN 15.A N LEU 20.A O no hydrogen 2.730 N/A ASN 15.A ND2 SER 213.A OG no hydrogen 2.827 N/A ASN 15.A ND2 ILE 226.A O no hydrogen 3.067 N/A SER 16.A OG MET 230.A O no hydrogen 2.715 N/A ARG 17.A N ASN 15.A OD1 no hydrogen 2.844 N/A ARG 17.A NE ASP 105.A OD1 no hydrogen 3.174 N/A ARG 17.A NE ASP 105.A OD2 no hydrogen 3.051 N/A ARG 17.A NH1 GLN 181.A OE1 no hydrogen 3.009 N/A ARG 17.A NH1 ASP 227.A O no hydrogen 2.812 N/A ARG 17.A NH2 ASP 105.A OD1 no hydrogen 2.944 N/A ARG 17.A NH2 GLN 181.A O no hydrogen 2.780 N/A ILE 22.A N LEU 13.A O no hydrogen 2.938 N/A ASP 23.A N ARG 212.A O no hydrogen 2.818 N/A VAL 24.A N ARG 212.A O no hydrogen 3.202 N/A TYR 26.A N PHE 210.A O no hydrogen 2.917 N/A THR 27.A N GLY 282.A O no hydrogen 3.123 N/A THR 27.A OG1 SER 280.A O.A no hydrogen 2.766 N/A THR 27.A OG1 SER 280.A O.B no hydrogen 2.830 N/A GLU 31.A N ASN 28.A O no hydrogen 3.004 N/A GLN 36.A NE2 ALA 196.A O no hydrogen 2.991 N/A GLN 38.A N ASP 105.A OD2 no hydrogen 2.891 N/A GLN 38.A NE2 GLN 36.A O no hydrogen 2.896 N/A GLN 38.A NE2 ALA 196.A O no hydrogen 3.125 N/A ASN 39.A N ASP 105.A OD2 no hydrogen 2.993 N/A ASN 39.A ND2 THR 103.A O no hydrogen 2.853 N/A ARG 41.A N THR 52.A OG1 no hydrogen 2.888 N/A ARG 41.A NH1 CYS 37.A O no hydrogen 2.844 N/A ARG 41.A NH1 PRO 197.A O no hydrogen 2.927 N/A ARG 41.A NH2 PRO 197.A O no hydrogen 2.908 N/A ARG 41.A NH2 ASN 271.A OD1 no hydrogen 2.698 N/A CYS 42.A SG THR 43.A O no hydrogen 3.446 N/A THR 43.A N GLU 47.A O no hydrogen 2.936 N/A THR 43.A OG1 ASP 45.A OD2 no hydrogen 2.527 N/A LEU 44.A N ARG 270.A O no hydrogen 2.891 N/A GLY 46.A N THR 43.A O no hydrogen 2.910 N/A GLU 47.A N THR 43.A OG1 no hydrogen 2.999 N/A GLN 49.A N ARG 41.A O no hydrogen 2.910 N/A GLN 49.A NE2 ASN 271.A O no hydrogen 2.969 N/A THR 51.A N GLN 38.A O no hydrogen 2.941 N/A THR 51.A OG1 ASN 39.A OD1 no hydrogen 2.819 N/A THR 52.A N GLN 49.A O no hydrogen 3.002 N/A THR 52.A OG1 GLN 38.A O no hydrogen 2.897 N/A THR 52.A OG1 ARG 41.A O no hydrogen 3.476 N/A THR 52.A OG1 GLN 49.A O no hydrogen 3.081 N/A GLN 53.A NE2 LEU 55.A O no hydrogen 2.935 N/A LEU 55.A N GLN 53.A OE1 no hydrogen 2.956 N/A GLY 58.A N LEU 55.A O no hydrogen 3.035 N/A CYS 60.A N GLY 102.A O no hydrogen 2.790 N/A CYS 60.A SG ARG 17.A O no hydrogen 3.420 N/A ALA 61.A N GLY 58.A O no hydrogen 3.209 N/A ARG 63.A NH1 LEU 86.A O no hydrogen 3.052 N/A GLY 64.A N THR 163.A O no hydrogen 2.994 N/A LYS 65.A N THR 82.A O no hydrogen 3.000 N/A THR 67.A N ASN 80.A O no hydrogen 2.766 N/A THR 67.A OG1 ASN 80.A O no hydrogen 3.334 N/A VAL 70.A N HIS 78.A O no hydrogen 2.826 N/A HIS 74.A N ASP 72.A OD1 no hydrogen 3.016 N/A THR 77.A N THR 151.A O no hydrogen 3.048 N/A TRP 79.A N PHE 149.A O no hydrogen 2.869 N/A TRP 79.A NE1 THR 151.A OG1 no hydrogen 2.893 N/A ASN 80.A N GLN 68.A O no hydrogen 2.844 N/A ASN 80.A ND2 THR 67.A OG1 no hydrogen 2.838 N/A ASN 80.A ND2 ASN 146.A OD1 no hydrogen 2.767 N/A MET 81.A N ILE 147.A O no hydrogen 2.860 N/A THR 82.A N LYS 65.A O no hydrogen 2.798 N/A VAL 83.A N GLY 145.A O no hydrogen 2.891 N/A THR 84.A N ARG 63.A O no hydrogen 2.827 N/A THR 84.A OG1 ARG 63.A O no hydrogen 3.314 N/A THR 84.A OG1 ASN 85.A O no hydrogen 2.908 N/A ASN 85.A N THR 89.A O no hydrogen 2.875 N/A ASN 85.A ND2 THR 89.A O no hydrogen 3.400 N/A ASN 85.A ND2 THR 89.A OG1 no hydrogen 3.029 N/A GLY 88.A N ASN 85.A O no hydrogen 2.841 N/A THR 89.A N ASN 87.A OD1 no hydrogen 2.993 N/A THR 89.A OG1 ASN 87.A OD1 no hydrogen 2.678 N/A THR 94.A N ASP 92.A OD2 no hydrogen 3.015 N/A THR 94.A OG1 ASP 92.A OD1 no hydrogen 3.110 N/A THR 94.A OG1 ASP 92.A OD2 no hydrogen 2.819 N/A GLU 95.A N ASP 92.A O no hydrogen 2.890 N/A VAL 97.A N GLU 95.A O no hydrogen 2.800 N/A GLY 102.A N THR 51.A O no hydrogen 2.801 N/A THR 103.A N PRO 100.A O no hydrogen 3.028 N/A THR 103.A OG1 PRO 100.A O no hydrogen 2.625 N/A SER 107.A N THR 183.A O no hydrogen 2.905 N/A SER 107.A OG HIS 178.A O no hydrogen 2.642 N/A GLY 108.A N THR 135.A OG1 no hydrogen 2.917 N/A GLN 109.A NE2 TYR 136.A OH no hydrogen 2.866 N/A ILE 110.A N ILE 133.A O no hydrogen 2.860 N/A TYR 111.A N GLY 169.A O no hydrogen 2.732 N/A TYR 111.A OH GLU 130.A OE2 no hydrogen 2.533 N/A GLY 112.A N ALA 131.A O no hydrogen 2.938 N/A VAL 113.A N THR 166.A O no hydrogen 2.895 N/A ILE 114.A N HIS 129.A O no hydrogen 2.910 N/A SER 115.A N LYS 164.A O no hydrogen 2.879 N/A GLN 116.A N ARG 127.A O no hydrogen 2.836 N/A GLN 116.A NE2 SER 158.A O no hydrogen 2.922 N/A GLN 116.A NE2 THR 163.A OG1 no hydrogen 2.950 N/A ARG 117.A NE ASN 126.A OD1 no hydrogen 2.712 N/A ARG 117.A NH2 ASN 126.A OD1 no hydrogen 3.228 N/A ASN 118.A N ALA 125.A O no hydrogen 2.949 N/A THR 119.A N GLN 161.A OE1 no hydrogen 3.137 N/A ARG 127.A N GLN 116.A O no hydrogen 3.209 N/A ARG 127.A NH1 GLN 116.A OE1 no hydrogen 3.104 N/A ARG 127.A NH1 ASN 118.A OD1 no hydrogen 2.985 N/A ARG 127.A NH2 ASN 118.A OD1 no hydrogen 3.293 N/A HIS 129.A N ILE 114.A O no hydrogen 2.851 N/A HIS 129.A NE2 ASP 156.A OD2 no hydrogen 2.704 N/A ALA 131.A N GLY 112.A O no hydrogen 2.847 N/A VAL 132.A N SER 150.A O no hydrogen 2.832 N/A ILE 133.A N ILE 110.A O no hydrogen 2.815 N/A THR 135.A N GLY 108.A O no hydrogen 2.969 N/A THR 135.A OG1 PHE 106.A O no hydrogen 2.607 N/A THR 135.A OG1 GLY 108.A O no hydrogen 3.307 N/A SER 137.A N ALA 134.A O no hydrogen 3.235 N/A LYS 139.A N SER 137.A OG no hydrogen 2.950 N/A PHE 140.A N SER 137.A O no hydrogen 2.875 N/A THR 141.A N ASN 146.A O no hydrogen 3.037 N/A THR 141.A OG1 ASN 146.A O no hydrogen 2.808 N/A LYS 143.A N TYR 187.A O no hydrogen 2.990 N/A LYS 143.A NZ PRO 93.A O no hydrogen 2.754 N/A LYS 143.A NZ VAL 97.A O no hydrogen 2.866 N/A LEU 144.A N THR 141.A O no hydrogen 2.813 N/A GLY 145.A N PRO 142.A O no hydrogen 2.932 N/A ASN 146.A N THR 141.A O no hydrogen 3.312 N/A ASN 146.A ND2 ASN 80.A OD1 no hydrogen 2.612 N/A ILE 147.A N MET 81.A O no hydrogen 2.934 N/A GLN 148.A NE2 ASN 80.A OD1 no hydrogen 3.486 N/A PHE 149.A N TRP 79.A O no hydrogen 3.032 N/A SER 150.A N VAL 132.A O no hydrogen 2.915 N/A THR 151.A N THR 77.A O no hydrogen 2.821 N/A THR 151.A OG1 GLU 153.A O no hydrogen 2.641 N/A GLN 155.A N GLU 153.A OE2 no hydrogen 2.938 N/A ASP 156.A N GLU 153.A OE2 no hydrogen 2.934 N/A VAL 157.A N GLN 155.A O no hydrogen 2.821 N/A SER 158.A N GLN 116.A OE1 no hydrogen 2.856 N/A SER 159.A OG THR 67.A O no hydrogen 3.317 N/A GLY 160.A N VAL 66.A O no hydrogen 2.734 N/A GLN 161.A NE2 ASN 120.A OD1 no hydrogen 3.218 N/A THR 163.A N GLY 64.A O no hydrogen 2.786 N/A THR 163.A OG1 GLN 161.A O no hydrogen 2.704 N/A LYS 164.A N SER 115.A O no hydrogen 2.831 N/A PHE 165.A N PHE 62.A O no hydrogen 2.886 N/A THR 166.A N VAL 113.A O no hydrogen 2.816 N/A VAL 168.A N TYR 111.A O no hydrogen 2.851 N/A GLY 169.A N TYR 111.A O no hydrogen 2.989 N/A LEU 170.A N PRO 216.A O no hydrogen 2.813 N/A ALA 171.A N GLN 109.A O no hydrogen 2.806 N/A ASP 174.A N SER 172.A OG no hydrogen 2.998 N/A SER 177.A N ASP 174.A O no hydrogen 2.835 N/A SER 177.A OG SER 172.A O no hydrogen 3.206 N/A SER 177.A OG ASP 174.A O no hydrogen 2.803 N/A ASP 180.A N SER 107.A O no hydrogen 2.975 N/A GLN 181.A NE2 ASP 227.A OD2 no hydrogen 2.835 N/A TRP 182.A N ASP 180.A OD2 no hydrogen 3.068 N/A THR 183.A N ASP 180.A O no hydrogen 3.159 N/A TYR 187.A N ASN 192.A OD1 no hydrogen 2.929 N/A GLY 189.A N SER 186.A O no hydrogen 2.808 N/A ASN 192.A ND2 PRO 185.A O no hydrogen 2.932 N/A ALA 196.A N GLN 38.A OE1 no hydrogen 2.823 N/A VAL 199.A N VAL 35.A O no hydrogen 2.930 N/A GLU 206.A N PHE 203.A O no hydrogen 3.292 N/A CYS 207.A N VAL 276.A O no hydrogen 2.758 N/A CYS 207.A SG LEU 208.A O no hydrogen 3.752 N/A CYS 207.A SG VAL 276.A O no hydrogen 3.911 N/A CYS 207.A SG ARG 278.A O no hydrogen 3.498 N/A LEU 209.A N LEU 274.A O no hydrogen 2.956 N/A PHE 210.A N TYR 26.A O no hydrogen 2.841 N/A PHE 211.A N CYS 228.A O no hydrogen 2.962 N/A ARG 212.A N VAL 24.A O no hydrogen 2.819 N/A ARG 212.A NE ASP 227.A OD1 no hydrogen 2.836 N/A ARG 212.A NH2 ASP 227.A OD2 no hydrogen 2.895 N/A SER 213.A N ILE 226.A O no hydrogen 2.958 N/A SER 213.A OG PRO 21.A O no hydrogen 2.765 N/A PHE 214.A N ASP 23.A OD2 no hydrogen 2.797 N/A ILE 215.A N PRO 224.A O no hydrogen 2.973 N/A LYS 218.A N LEU 170.A O no hydrogen 2.872 N/A LYS 218.A NZ GLU 130.A OE2 no hydrogen 2.641 N/A ILE 226.A N SER 213.A O no hydrogen 2.831 N/A ASP 227.A N GLN 181.A OE1 no hydrogen 2.778 N/A CYS 228.A N PHE 211.A O no hydrogen 2.879 N/A CYS 228.A SG PHE 211.A O no hydrogen 3.668 N/A CYS 228.A SG MET 230.A O no hydrogen 3.349 N/A GLN 232.A N THR 14.A O no hydrogen 2.875 N/A GLN 232.A NE2 GLN 53.A O no hydrogen 3.024 N/A GLN 232.A NE2 LEU 54.A O no hydrogen 2.940 N/A GLU 233.A N GLU 233.A OE1 no hydrogen 2.788 N/A TRP 234.A N PRO 231.A O no hydrogen 2.972 N/A VAL 235.A N PRO 231.A O no hydrogen 3.235 N/A GLN 236.A N GLN 232.A O no hydrogen 2.918 N/A GLN 236.A NE2 LEU 54.A O no hydrogen 2.988 N/A HIS 237.A N GLU 233.A O no hydrogen 2.891 N/A HIS 237.A NE2 THR 4.A OG1 no hydrogen 2.831 N/A LEU 238.A N TRP 234.A O no hydrogen 2.824 N/A TYR 239.A N VAL 235.A O no hydrogen 2.994 N/A GLN 240.A N GLN 236.A O no hydrogen 3.034 N/A GLU 241.A N HIS 237.A O no hydrogen 2.904 N/A SER 242.A N LEU 238.A O no hydrogen 2.954 N/A SER 242.A OG ASP 45.A O no hydrogen 3.335 N/A SER 247.A OG VAL 298.A O no hydrogen 2.656 N/A VAL 249.A N SER 247.A OG no hydrogen 3.184 N/A ALA 250.A N LEU 268.A O no hydrogen 2.791 N/A LEU 251.A N SER 296.A O no hydrogen 2.652 N/A VAL 252.A N ALA 266.A O no hydrogen 2.956 N/A ARG 253.A N ARG 293.A O no hydrogen 2.818 N/A ARG 253.A NE ASP 295.A OD1 no hydrogen 2.775 N/A TYR 254.A N PHE 264.A O no hydrogen 2.860 N/A VAL 255.A N TYR 291.A O no hydrogen 2.783 N/A ASN 256.A N ARG 261.A O no hydrogen 2.870 N/A GLU 258.A N ASN 256.A OD1 no hydrogen 2.782 N/A THR 259.A N ASN 256.A OD1 no hydrogen 3.304 N/A GLY 260.A N ASN 256.A O no hydrogen 2.515 N/A ARG 261.A N THR 259.A OG1 no hydrogen 3.083 N/A LEU 263.A N TYR 254.A O no hydrogen 2.719 N/A ALA 266.A N VAL 252.A O no hydrogen 2.966 N/A LYS 267.A N THR 275.A O no hydrogen 2.904 N/A LYS 267.A NZ GLU 206.A OE1 no hydrogen 2.686 N/A LYS 267.A NZ GLN 300.A O no hydrogen 3.294 N/A LYS 267.A NZ TYR 302.A O no hydrogen 2.668 N/A LEU 268.A N ALA 250.A O no hydrogen 2.706 N/A HIS 269.A N PHE 273.A O no hydrogen 2.813 N/A HIS 269.A NE2 THR 275.A OG1 no hydrogen 2.941 N/A ARG 270.A N ASP 248.A O no hydrogen 2.885 N/A ASN 271.A ND2 GLN 49.A OE1 no hydrogen 3.005 N/A GLY 272.A N HIS 269.A O no hydrogen 2.747 N/A THR 275.A N LYS 267.A O no hydrogen 2.882 N/A THR 275.A OG1 GLU 206.A OE2 no hydrogen 2.736 N/A THR 275.A OG1 HIS 269.A NE2 no hydrogen 2.941 N/A VAL 276.A N CYS 207.A O no hydrogen 2.826 N/A ARG 278.A NH1 THR 27.A OG1 no hydrogen 2.852 N/A ARG 278.A NH1 GLY 282.A O no hydrogen 3.031 N/A ARG 278.A NH2 PRO 283.A O no hydrogen 3.293 N/A GLY 282.A N THR 27.A O no hydrogen 2.758 N/A VAL 284.A N LEU 25.A O no hydrogen 2.729 N/A ASN 289.A ND2 ASN 256.A OD1 no hydrogen 3.231 N/A GLY 290.A N PRO 287.A O no hydrogen 3.222 N/A TYR 291.A N VAL 255.A O no hydrogen 3.146 N/A ARG 293.A N ARG 253.A O no hydrogen 2.723 N/A ASP 295.A N LEU 251.A O no hydrogen 2.851 N/A SER 296.A N LEU 251.A O no hydrogen 3.301 N/A SER 296.A OG ASP 295.A OD2 no hydrogen 2.717 N/A VAL 298.A N VAL 249.A O no hydrogen 2.790 N/A GLN 300.A NE2 ASP 248.A OD2 no hydrogen 2.893 N/A GLN 300.A NE2 HIS 269.A ND1 no hydrogen 3.512 N/A PHE 301.A N ASN 299.A OD1 no hydrogen 2.826 N/A TYR 302.A N ASN 299.A O no hydrogen 3.180 N/A ALA 305.A N GLU 265.A OE2 no hydrogen 3.204 N/A MET 307.A N ALA 277.A O no hydrogen 2.873 N/A