Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4xda_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 2.A ND2 ASP 54.A OD1 no hydrogen 2.837 N/A LYS 3.A N ASP 54.A OD2 no hydrogen 3.092 N/A LEU 4.A N ASP 54.A O no hydrogen 2.962 N/A VAL 5.A N TYR 134.A O no hydrogen 2.974 N/A VAL 6.A N GLY 56.A O no hydrogen 2.848 N/A LEU 7.A N LEU 136.A O no hydrogen 2.978 N/A GLY 8.A N ILE 58.A O no hydrogen 3.207 N/A SER 9.A OG GLU 140.A OE1 no hydrogen 2.468 N/A VAL 10.A N ASN 114.A OD1 no hydrogen 2.947 N/A ASN 11.A N GLY 38.A O no hydrogen 3.115 N/A ASN 11.A ND2 GLU 140.A OE1 no hydrogen 3.513 N/A ALA 12.A N GLY 93.A O no hydrogen 2.887 N/A ASP 13.A N ILE 36.A O no hydrogen 2.703 N/A HIS 14.A N ALA 95.A O no hydrogen 2.755 N/A HIS 14.A ND1 TYR 33.A OH no hydrogen 2.634 N/A VAL 15.A N GLN 34.A O no hydrogen 2.874 N/A LEU 16.A N ILE 97.A O no hydrogen 2.866 N/A GLN 17.A N ARG 31.A O no hydrogen 2.911 N/A VAL 18.A N VAL 99.A O no hydrogen 3.001 N/A ARG 31.A N GLN 17.A O no hydrogen 2.855 N/A ASN 32.A ND2 GLN 17.A OE1 no hydrogen 2.848 N/A TYR 33.A OH HIS 14.A ND1 no hydrogen 2.634 N/A GLN 34.A N VAL 15.A O no hydrogen 3.051 N/A ILE 36.A N ASP 13.A O no hydrogen 2.779 N/A GLY 38.A N ASN 11.A O no hydrogen 2.819 N/A LYS 40.A N GLU 140.A OE1 no hydrogen 3.130 N/A LYS 40.A NZ GLU 140.A OE2 no hydrogen 3.135 N/A GLY 41.A N SER 9.A OG no hydrogen 3.275 N/A ALA 42.A N SER 9.A O no hydrogen 2.754 N/A ASN 43.A N GLY 39.A O no hydrogen 2.816 N/A ASN 43.A ND2 ASP 252.A OD2 no hydrogen 2.804 N/A GLN 44.A N LYS 40.A O no hydrogen 3.005 N/A GLN 44.A NE2 ASN 163.A OD1 no hydrogen 2.943 N/A GLN 44.A NE2 ASP 252.A OD1 no hydrogen 2.997 N/A ALA 45.A N GLY 41.A O no hydrogen 2.948 N/A VAL 46.A N ALA 42.A O no hydrogen 2.833 N/A ALA 47.A N ASN 43.A O no hydrogen 2.840 N/A ALA 48.A N GLN 44.A O no hydrogen 2.979 N/A ALA 49.A N ALA 45.A O no hydrogen 2.879 N/A ARG 50.A N VAL 46.A O no hydrogen 2.870 N/A ARG 50.A NE ASP 77.A OD1 no hydrogen 2.995 N/A ARG 50.A NH1 GLN 289.A O no hydrogen 2.872 N/A ARG 50.A NH1 ILE 292.A O no hydrogen 2.961 N/A ARG 50.A NH2 ASP 77.A OD2 no hydrogen 2.949 N/A MET 51.A N ALA 47.A O no hydrogen 2.952 N/A GLN 52.A N ALA 49.A O no hydrogen 2.882 N/A ALA 53.A N ALA 48.A O no hydrogen 2.936 N/A GLY 56.A N LEU 4.A O no hydrogen 2.844 N/A PHE 57.A N ASN 80.A O no hydrogen 3.008 N/A ILE 58.A N VAL 6.A O no hydrogen 2.818 N/A ALA 59.A N GLY 83.A O no hydrogen 3.164 N/A VAL 61.A N LYS 85.A O no hydrogen 2.865 N/A GLY 62.A N THR 92.A OG1 no hydrogen 2.863 N/A ASP 63.A N CYS 90.A O no hydrogen 3.010 N/A GLY 67.A N ASP 64.A OD1 no hydrogen 2.934 N/A ILE 68.A N ASP 64.A O no hydrogen 3.179 N/A ASN 69.A N SER 65.A O no hydrogen 2.917 N/A ILE 70.A N PHE 66.A O no hydrogen 2.802 N/A ARG 71.A N GLY 67.A O no hydrogen 3.129 N/A ARG 71.A NH1 VAL 84.A O no hydrogen 2.954 N/A GLU 72.A N ILE 68.A O no hydrogen 3.263 N/A SER 73.A N ASN 69.A O no hydrogen 2.906 N/A SER 73.A OG ASN 69.A O no hydrogen 3.150 N/A PHE 74.A N ILE 70.A O no hydrogen 2.974 N/A LYS 75.A N GLU 72.A O no hydrogen 3.131 N/A LYS 75.A NZ GLU 72.A OE1 no hydrogen 2.964 N/A LYS 75.A NZ GLU 72.A OE2 no hydrogen 3.398 N/A LEU 76.A N SER 73.A O no hydrogen 2.991 N/A ASP 77.A N PHE 74.A O no hydrogen 3.071 N/A GLY 78.A N LYS 75.A O no hydrogen 2.911 N/A ILE 79.A N PHE 74.A O no hydrogen 3.009 N/A ASN 80.A N VAL 55.A O no hydrogen 3.021 N/A ASN 80.A ND2 ASN 2.A OD1 no hydrogen 2.901 N/A ALA 82.A N ASN 80.A OD1 no hydrogen 2.959 N/A VAL 84.A N THR 81.A O no hydrogen 2.871 N/A LYS 85.A N ALA 59.A O no hydrogen 2.746 N/A LYS 85.A NZ GLY 83.A O no hydrogen 3.079 N/A LYS 85.A NZ ASP 125.A OD1 no hydrogen 3.398 N/A LYS 85.A NZ ASP 125.A OD2 no hydrogen 2.612 N/A GLN 87.A N VAL 61.A O no hydrogen 2.881 N/A ASN 89.A N ASP 63.A OD2 no hydrogen 2.906 N/A THR 92.A N ASP 64.A OD2 no hydrogen 2.964 N/A THR 92.A OG1 ASP 64.A OD1 no hydrogen 2.757 N/A ILE 94.A N SER 110.A O no hydrogen 3.116 N/A ALA 95.A N ALA 12.A O no hydrogen 3.013 N/A MET 96.A N CYS 108.A O no hydrogen 2.771 N/A ILE 97.A N HIS 14.A O no hydrogen 2.894 N/A GLN 98.A N SER 106.A O no hydrogen 3.106 N/A VAL 99.A N LEU 16.A O no hydrogen 2.972 N/A SER 100.A N GLU 104.A O no hydrogen 2.954 N/A SER 100.A OG SER 102.A OG no hydrogen 2.709 N/A SER 100.A OG GLU 104.A O no hydrogen 3.568 N/A SER 102.A OG SER 100.A OG no hydrogen 2.709 N/A SER 102.A OG GLU 104.A OE1 no hydrogen 2.823 N/A GLY 103.A N SER 100.A O no hydrogen 2.920 N/A GLU 104.A N SER 102.A OG no hydrogen 3.359 N/A SER 106.A N GLN 98.A O no hydrogen 2.989 N/A CYS 108.A N MET 96.A O no hydrogen 3.002 N/A SER 110.A N ILE 94.A O no hydrogen 2.977 N/A SER 110.A OG GLU 112.A OE2 no hydrogen 2.786 N/A ALA 113.A N PRO 91.A O no hydrogen 3.019 N/A ASN 114.A N ALA 111.A O no hydrogen 3.005 N/A ASN 114.A ND2 VAL 10.A O no hydrogen 3.044 N/A ASN 114.A ND2 ASN 11.A OD1 no hydrogen 2.999 N/A ASN 114.A ND2 ALA 111.A O no hydrogen 3.228 N/A ALA 115.A N GLU 112.A O no hydrogen 3.001 N/A LYS 116.A N ALA 113.A O no hydrogen 2.929 N/A LEU 117.A N ASN 114.A O no hydrogen 3.216 N/A THR 118.A N LYS 116.A O no hydrogen 2.951 N/A ALA 119.A N ASP 144.A OD2 no hydrogen 2.839 N/A ALA 121.A N THR 118.A OG1 no hydrogen 3.179 N/A ILE 122.A N THR 118.A O no hydrogen 3.224 N/A ILE 122.A N ALA 119.A O no hydrogen 3.226 N/A GLU 123.A N ALA 120.A O no hydrogen 3.227 N/A ASP 125.A N ILE 122.A O no hydrogen 2.749 N/A LEU 126.A N GLU 123.A O no hydrogen 3.383 N/A ILE 129.A N ASP 125.A O no hydrogen 3.094 N/A ARG 130.A N LEU 126.A O no hydrogen 3.070 N/A ARG 130.A NH1 GLU 152.A OE1 no hydrogen 2.831 N/A ASP 131.A N ALA 127.A O no hydrogen 2.958 N/A ALA 132.A N ALA 128.A O no hydrogen 3.094 N/A ARG 133.A N LYS 3.A O no hydrogen 2.763 N/A TYR 134.A N LYS 3.A O no hydrogen 3.059 N/A LEU 135.A N ASN 159.A O no hydrogen 2.730 N/A LEU 136.A N VAL 5.A O no hydrogen 2.907 N/A MET 137.A N ILE 161.A O no hydrogen 2.973 N/A GLN 138.A NE2 GLN 44.A OE1 no hydrogen 2.766 N/A LEU 139.A N ALA 165.A O no hydrogen 2.896 N/A GLY 145.A N PRO 142.A O no hydrogen 3.122 N/A ILE 146.A N PRO 142.A O no hydrogen 3.300 N/A LEU 147.A N LEU 143.A O no hydrogen 2.881 N/A LYS 148.A N ASP 144.A O no hydrogen 3.131 N/A ALA 149.A N GLY 145.A O no hydrogen 3.072 N/A ALA 150.A N ILE 146.A O no hydrogen 3.061 N/A GLN 151.A N LEU 147.A O no hydrogen 2.881 N/A GLU 152.A N LYS 148.A O no hydrogen 2.914 N/A ALA 153.A N ALA 149.A O no hydrogen 2.946 N/A LYS 154.A N ALA 150.A O no hydrogen 3.325 N/A LYS 154.A NZ CYS 177.A O no hydrogen 2.384 N/A LYS 154.A NZ ASP 179.A OD2 no hydrogen 2.908 N/A THR 155.A N GLU 152.A O no hydrogen 3.341 N/A ALA 156.A N ALA 153.A O no hydrogen 3.241 N/A THR 158.A N ALA 153.A O no hydrogen 3.054 N/A THR 158.A OG1 ILE 129.A O no hydrogen 2.819 N/A THR 158.A OG1 ALA 132.A O no hydrogen 3.101 N/A THR 158.A OG1 ALA 156.A O no hydrogen 3.332 N/A ASN 159.A N ARG 133.A O no hydrogen 2.769 N/A ASN 159.A ND2 ARG 133.A O no hydrogen 2.974 N/A VAL 160.A N ASP 179.A OD2 no hydrogen 2.719 N/A ILE 161.A N LEU 135.A O no hydrogen 2.804 N/A LEU 162.A N LEU 180.A O no hydrogen 2.973 N/A ASN 163.A N MET 137.A O no hydrogen 2.831 N/A ASN 163.A ND2 THR 182.A O no hydrogen 3.132 N/A ASN 163.A ND2 THR 182.A OG1 no hydrogen 3.257 N/A ALA 165.A N ASN 163.A O no hydrogen 2.673 N/A ARG 168.A NE GLU 169.A O no hydrogen 2.699 N/A ARG 168.A NH2 GLU 169.A O no hydrogen 3.245 N/A GLU 173.A N GLU 173.A OE2 no hydrogen 2.838 N/A LEU 174.A N PRO 171.A O no hydrogen 2.996 N/A LEU 175.A N PRO 171.A O no hydrogen 3.263 N/A LYS 176.A N ASP 172.A O no hydrogen 3.081 N/A CYS 177.A N LEU 174.A O no hydrogen 2.860 N/A CYS 177.A SG GLU 173.A O no hydrogen 3.814 N/A VAL 178.A N LEU 175.A O no hydrogen 3.051 N/A ASP 179.A N VAL 160.A O no hydrogen 2.845 N/A LEU 180.A N VAL 160.A O no hydrogen 3.124 N/A ILE 181.A N ILE 216.A O no hydrogen 3.071 N/A THR 182.A N LEU 162.A O no hydrogen 3.029 N/A THR 182.A OG1 LEU 162.A O no hydrogen 3.528 N/A THR 182.A OG1 ASN 255.A OD1 no hydrogen 2.670 N/A ASN 184.A N GLU 187.A OE1 no hydrogen 2.936 N/A GLU 187.A N ASN 184.A OD1 no hydrogen 2.653 N/A ALA 188.A N ASN 184.A O no hydrogen 2.963 N/A GLU 189.A N GLU 185.A O no hydrogen 3.370 N/A GLU 189.A N THR 186.A O no hydrogen 3.203 N/A VAL 190.A N THR 186.A O no hydrogen 3.064 N/A LEU 191.A N GLU 187.A O no hydrogen 2.984 N/A THR 192.A N ALA 188.A O no hydrogen 2.950 N/A THR 192.A OG1 ALA 188.A O no hydrogen 2.788 N/A GLY 193.A N GLU 189.A O no hydrogen 2.677 N/A ILE 194.A N THR 192.A OG1 no hydrogen 3.108 N/A THR 195.A OG1 GLU 189.A OE1 no hydrogen 2.979 N/A TYR 197.A N SER 201.A OG no hydrogen 2.823 N/A ASP 198.A N SER 201.A OG no hydrogen 2.939 N/A SER 200.A OG ASP 198.A OD1 no hydrogen 3.416 N/A SER 200.A OG ASP 198.A OD2 no hydrogen 3.095 N/A SER 201.A N ASP 198.A OD1 no hydrogen 2.952 N/A SER 201.A OG ASP 198.A O no hydrogen 3.124 N/A SER 201.A OG ASP 198.A OD1 no hydrogen 2.514 N/A ALA 202.A N ASP 198.A O no hydrogen 2.900 N/A GLN 203.A N ASP 199.A O no hydrogen 3.011 N/A GLN 203.A NE2 SER 229.A OG no hydrogen 3.116 N/A GLN 204.A N SER 200.A O no hydrogen 2.976 N/A ALA 205.A N SER 201.A O no hydrogen 3.004 N/A ALA 206.A N ALA 202.A O no hydrogen 2.990 N/A ASP 207.A N GLN 203.A O no hydrogen 2.923 N/A ALA 208.A N GLN 204.A O no hydrogen 2.934 N/A LEU 209.A N ALA 205.A O no hydrogen 3.124 N/A HIS 210.A N ALA 206.A O no hydrogen 2.740 N/A HIS 210.A ND1 ILE 214.A O no hydrogen 2.917 N/A HIS 210.A NE2 SER 229.A OG no hydrogen 2.465 N/A CYS 211.A N ASP 207.A O no hydrogen 2.782 N/A CYS 211.A SG ASP 207.A O no hydrogen 3.254 N/A LYS 212.A N ALA 208.A O no hydrogen 3.258 N/A LYS 212.A NZ ASP 172.A OD1 no hydrogen 2.753 N/A LYS 212.A NZ ASP 172.A OD2 no hydrogen 3.075 N/A GLY 213.A N HIS 210.A O no hydrogen 2.932 N/A ILE 214.A N LEU 209.A O no hydrogen 3.242 N/A ILE 216.A N ASP 179.A O no hydrogen 3.139 N/A VAL 217.A N SER 229.A O no hydrogen 2.948 N/A ILE 218.A N ILE 181.A O no hydrogen 2.890 N/A ILE 219.A N TRP 227.A O no hydrogen 2.915 N/A THR 220.A N PRO 183.A O no hydrogen 2.809 N/A THR 220.A OG1 PRO 183.A O no hydrogen 3.569 N/A LEU 221.A N GLY 225.A O no hydrogen 2.741 N/A LYS 224.A N LEU 221.A O no hydrogen 3.086 N/A GLY 225.A N GLY 222.A O no hydrogen 3.046 N/A VAL 226.A N ILE 237.A O no hydrogen 2.909 N/A TRP 227.A N ILE 219.A O no hydrogen 2.722 N/A TRP 227.A NE1 GLN 203.A OE1 no hydrogen 2.602 N/A LEU 228.A N GLN 235.A O no hydrogen 2.819 N/A SER 229.A N VAL 217.A O no hydrogen 2.814 N/A SER 229.A OG HIS 210.A NE2 no hydrogen 2.465 N/A GLN 230.A N ARG 233.A O no hydrogen 2.820 N/A ASN 231.A N GLU 215.A O no hydrogen 3.424 N/A ARG 233.A N GLN 230.A O no hydrogen 3.374 N/A GLN 235.A N LEU 228.A O no hydrogen 2.900 N/A GLN 235.A NE2 GLU 269.A OE1 no hydrogen 2.904 N/A ARG 236.A NH1 LYS 224.A O no hydrogen 2.686 N/A ILE 237.A N VAL 226.A O no hydrogen 2.847 N/A THR 245.A N VAL 283.A O no hydrogen 2.864 N/A THR 245.A OG1 THR 284.A O no hydrogen 3.151 N/A ASP 246.A N VAL 283.A O no hydrogen 3.239 N/A THR 247.A N GLY 103.A O no hydrogen 3.066 N/A THR 247.A OG1 GLY 103.A O no hydrogen 3.413 N/A THR 247.A OG1 ASN 105.A OD1 no hydrogen 2.741 N/A THR 248.A N ASP 246.A OD1 no hydrogen 3.049 N/A THR 248.A OG1 ASP 246.A OD1 no hydrogen 2.746 N/A THR 248.A OG1 ASP 246.A OD2 no hydrogen 3.542 N/A ALA 250.A N THR 247.A O no hydrogen 3.022 N/A THR 253.A N ALA 249.A O no hydrogen 2.790 N/A THR 253.A OG1 ALA 249.A O no hydrogen 2.950 N/A PHE 254.A N ALA 250.A O no hydrogen 2.877 N/A ASN 255.A N GLY 251.A O no hydrogen 2.998 N/A ASN 255.A ND2 GLY 251.A O no hydrogen 2.905 N/A GLY 256.A N ASP 252.A O no hydrogen 2.952 N/A ALA 257.A N THR 253.A O no hydrogen 3.014 N/A LEU 258.A N PHE 254.A O no hydrogen 2.889 N/A VAL 259.A N ASN 255.A O no hydrogen 3.100 N/A THR 260.A N GLY 256.A O no hydrogen 3.214 N/A THR 260.A OG1 GLY 256.A O no hydrogen 2.764 N/A GLY 261.A N ALA 257.A O no hydrogen 2.794 N/A LEU 262.A N LEU 258.A O no hydrogen 2.940 N/A LEU 263.A N VAL 259.A O no hydrogen 2.840 N/A GLN 264.A N THR 260.A O no hydrogen 2.931 N/A GLU 265.A N LEU 262.A O no hydrogen 2.889 N/A MET 266.A N GLY 261.A O no hydrogen 2.981 N/A ALA 271.A N PRO 267.A O no hydrogen 2.914 N/A ILE 272.A N LEU 268.A O no hydrogen 3.063 N/A LYS 273.A N GLU 269.A O no hydrogen 3.211 N/A LYS 273.A NZ PRO 238.A O no hydrogen 2.720 N/A PHE 274.A N SER 270.A O no hydrogen 2.955 N/A ALA 275.A N ALA 271.A O no hydrogen 2.888 N/A HIS 276.A N ILE 272.A O no hydrogen 2.748 N/A HIS 276.A NE2 ILE 237.A O no hydrogen 3.063 N/A ALA 277.A N LYS 273.A O no hydrogen 3.033 N/A ALA 278.A N PHE 274.A O no hydrogen 3.165 N/A ALA 279.A N ALA 275.A O no hydrogen 2.943 N/A ALA 280.A N HIS 276.A O no hydrogen 2.808 N/A ILE 281.A N ALA 277.A O no hydrogen 3.040 N/A SER 282.A N ALA 278.A O no hydrogen 3.088 N/A SER 282.A OG ALA 279.A O no hydrogen 2.674 N/A VAL 283.A N ALA 279.A O no hydrogen 2.953 N/A THR 284.A N ILE 281.A O no hydrogen 2.989 N/A THR 284.A OG1 ILE 281.A O no hydrogen 2.614 N/A ARG 285.A N SER 282.A O no hydrogen 3.047 N/A ARG 285.A NH1 GLU 297.A OE1 no hydrogen 3.372 N/A ARG 285.A NH1 GLU 297.A OE2 no hydrogen 3.150 N/A ARG 285.A NH2 GLU 297.A OE1 no hydrogen 2.841 N/A GLY 287.A N ASP 246.A OD2 no hydrogen 2.845 N/A GLN 289.A N PRO 37.A O no hydrogen 3.124 N/A GLN 289.A NE2 ASN 43.A OD1 no hydrogen 2.905 N/A THR 290.A OG1 PHE 286.A O no hydrogen 2.692 N/A SER 291.A N ALA 288.A O no hydrogen 3.064 N/A SER 291.A OG GLY 287.A O no hydrogen 2.793 N/A SER 291.A OG ALA 288.A O no hydrogen 2.858 N/A ILE 292.A N GLN 289.A O no hydrogen 3.380 N/A THR 294.A N GLU 297.A OE2 no hydrogen 2.902 N/A THR 294.A OG1 GLU 297.A OE2 no hydrogen 3.500 N/A ARG 295.A N ARG 50.A O no hydrogen 3.066 N/A ARG 295.A NE GLU 299.A OE2 no hydrogen 2.887 N/A ARG 295.A NH1 MET 51.A O no hydrogen 2.938 N/A ARG 295.A NH1 GLN 264.A OE1 no hydrogen 2.765 N/A ARG 295.A NH2 GLU 299.A OE2 no hydrogen 3.231 N/A GLU 297.A N THR 294.A OG1 no hydrogen 3.295 N/A VAL 298.A N THR 294.A O no hydrogen 3.083 N/A GLU 299.A N ARG 295.A O no hydrogen 2.881 N/A ALA 300.A N ALA 296.A O no hydrogen 3.029 N/A PHE 301.A N GLU 297.A O no hydrogen 2.953 N/A LEU 302.A N VAL 298.A O no hydrogen 3.004 N/A ALA 303.A N GLU 299.A O no hydrogen 2.848 N/A GLU 304.A N ALA 300.A O no hydrogen 3.014 N/A HIS 305.A N PHE 301.A O no hydrogen 2.961 N/A