Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4xgh_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 5.A N LEU 17.A O no hydrogen 2.802 N/A SER 7.A N VAL 15.A O no hydrogen 2.642 N/A VAL 15.A N SER 7.A O no hydrogen 2.928 N/A LEU 17.A N THR 5.A O no hydrogen 2.631 N/A ILE 19.A N LYS 3.A O no hydrogen 3.409 N/A TYR 20.A N VAL 28.A O no hydrogen 2.937 N/A TYR 20.A OH ASP 30.A OD2 no hydrogen 3.240 N/A LYS 21.A N ASP 1.A OD1 no hydrogen 2.611 N/A VAL 28.A N TYR 20.A O no hydrogen 2.927 N/A ASP 30.A N PRO 18.A O no hydrogen 2.815 N/A ARG 32.A N ASP 30.A OD1 no hydrogen 3.006 N/A ARG 32.A NE ASP 30.A OD1 no hydrogen 2.989 N/A ARG 32.A NE ASP 30.A OD2 no hydrogen 3.094 N/A ARG 32.A NH2 ASP 30.A OD2 no hydrogen 2.682 N/A LEU 34.A N ILE 31.A O no hydrogen 3.142 N/A THR 38.A N LEU 34.A O no hydrogen 2.907 N/A THR 38.A OG1 LEU 34.A O no hydrogen 2.817 N/A GLY 39.A N TYR 35.A O no hydrogen 3.183 N/A LYS 40.A N THR 38.A OG1 no hydrogen 3.244 N/A PHE 47.A N ASP 44.A O no hydrogen 2.935 N/A SER 49.A N ASP 44.A OD2 no hydrogen 2.799 N/A THR 50.A N PHE 47.A O no hydrogen 3.010 N/A THR 50.A OG1 ASP 44.A OD2 no hydrogen 2.739 N/A CYS 53.A SG SER 52.A OG no hydrogen 3.760 N/A SER 55.A OG GLU 360.A OE1 no hydrogen 2.666 N/A SER 55.A OG GLU 360.A OE2 no hydrogen 3.482 N/A ALA 56.A N GLU 360.A OE2 no hydrogen 2.755 N/A ILE 57.A N SER 55.A OG no hydrogen 3.352 N/A THR 58.A OG1 ASP 225.A OD2 no hydrogen 2.681 N/A TYR 59.A N LEU 68.A O no hydrogen 3.153 N/A TYR 59.A OH ASP 61.A OD2 no hydrogen 3.368 N/A ASP 61.A N GLU 66.A O no hydrogen 2.836 N/A LYS 64.A N ASP 61.A OD1 no hydrogen 3.496 N/A GLY 65.A N GLY 62.A O no hydrogen 3.372 N/A GLU 66.A N ASP 61.A O no hydrogen 2.754 N/A LEU 68.A N TYR 59.A O no hydrogen 3.028 N/A TYR 69.A N TYR 72.A O no hydrogen 2.898 N/A TYR 69.A OH ILE 221.A O no hydrogen 3.098 N/A TYR 69.A OH ASP 225.A O no hydrogen 3.129 N/A ARG 70.A N ILE 57.A O no hydrogen 2.851 N/A ARG 70.A NE LEU 90.A O no hydrogen 3.260 N/A ARG 70.A NH1 ALA 56.A O no hydrogen 3.496 N/A ARG 70.A NH2 LEU 90.A O no hydrogen 2.810 N/A TYR 72.A N TYR 69.A O no hydrogen 2.993 N/A ILE 74.A N LEU 67.A O no hydrogen 2.798 N/A LEU 77.A N PRO 73.A O no hydrogen 2.802 N/A ALA 78.A N ILE 74.A O no hydrogen 3.112 N/A GLN 79.A N ASP 75.A O no hydrogen 3.269 N/A ASN 80.A N LEU 77.A O no hydrogen 2.973 N/A ASN 80.A ND2 ASN 76.A O no hydrogen 2.734 N/A PHE 83.A N ASP 217.A OD2 no hydrogen 2.891 N/A GLU 85.A N ASP 82.A OD1 no hydrogen 3.015 N/A SER 86.A N ASP 82.A O no hydrogen 3.160 N/A SER 86.A OG ASP 82.A O no hydrogen 2.917 N/A CYS 87.A N PHE 83.A O no hydrogen 2.786 N/A CYS 87.A SG PHE 83.A O no hydrogen 3.344 N/A TYR 88.A N LEU 84.A O no hydrogen 2.945 N/A LEU 89.A N GLU 85.A O no hydrogen 2.894 N/A LEU 90.A N SER 86.A O no hydrogen 3.009 N/A LEU 91.A N CYS 87.A O no hydrogen 3.004 N/A LYS 92.A N TYR 88.A O no hydrogen 2.723 N/A GLY 93.A N LEU 89.A O no hydrogen 2.761 N/A ASN 97.A N GLN 100.A OE1 no hydrogen 3.057 N/A GLN 100.A N ASN 97.A OD1 no hydrogen 2.615 N/A LYS 101.A N ASN 97.A O no hydrogen 2.997 N/A LYS 101.A NZ ASP 82.A OD1 no hydrogen 3.346 N/A LYS 101.A NZ ASP 82.A OD2 no hydrogen 2.718 N/A LYS 101.A NZ GLU 85.A OE2 no hydrogen 2.517 N/A LYS 102.A N ALA 98.A O no hydrogen 3.133 N/A GLU 103.A N ALA 99.A O no hydrogen 3.139 N/A PHE 104.A N GLN 100.A O no hydrogen 3.058 N/A VAL 105.A N LYS 101.A O no hydrogen 2.765 N/A ALA 106.A N LYS 102.A O no hydrogen 3.075 N/A THR 107.A N GLU 103.A O no hydrogen 3.033 N/A THR 107.A OG1 GLU 103.A O no hydrogen 2.812 N/A VAL 108.A N PHE 104.A O no hydrogen 3.041 N/A THR 109.A N VAL 105.A O no hydrogen 2.872 N/A THR 109.A OG1 VAL 105.A O no hydrogen 2.741 N/A LYS 110.A N ALA 106.A O no hydrogen 3.116 N/A HIS 111.A N VAL 108.A O no hydrogen 3.075 N/A HIS 111.A ND1 THR 107.A O no hydrogen 2.887 N/A THR 112.A N THR 109.A O no hydrogen 3.418 N/A THR 112.A OG1 THR 109.A O no hydrogen 2.928 N/A HIS 115.A N TYR 146.A OH no hydrogen 2.995 N/A GLN 117.A N HIS 115.A ND1 no hydrogen 3.007 N/A MET 118.A N HIS 115.A O no hydrogen 2.913 N/A GLN 119.A N HIS 115.A O no hydrogen 3.082 N/A GLN 119.A NE2 VAL 114.A O no hydrogen 2.855 N/A PHE 120.A N GLU 116.A O no hydrogen 2.839 N/A PHE 121.A N GLN 117.A O no hydrogen 2.877 N/A PHE 122.A N GLN 119.A O no hydrogen 3.218 N/A ARG 123.A N PHE 120.A O no hydrogen 2.944 N/A GLY 124.A N PHE 121.A O no hydrogen 3.201 N/A PHE 125.A N PHE 122.A O no hydrogen 3.096 N/A ARG 126.A NE ASP 128.A OD1 no hydrogen 2.913 N/A ARG 126.A NH2 ASP 128.A OD2 no hydrogen 2.772 N/A ARG 127.A NH1 TYR 175.A O no hydrogen 2.800 N/A ALA 129.A N ARG 126.A O no hydrogen 3.284 N/A ILE 134.A N HIS 130.A O no hydrogen 3.070 N/A LEU 135.A N PRO 131.A O no hydrogen 2.790 N/A VAL 136.A N MET 132.A O no hydrogen 2.939 N/A ALA 137.A N ALA 133.A O no hydrogen 3.232 N/A ALA 138.A N ILE 134.A O no hydrogen 2.795 N/A VAL 139.A N LEU 135.A O no hydrogen 2.852 N/A GLY 140.A N VAL 136.A O no hydrogen 3.024 N/A ALA 141.A N ALA 138.A O no hydrogen 2.917 N/A LEU 142.A N VAL 139.A O no hydrogen 3.212 N/A SER 143.A OG ASN 244.A OD1 no hydrogen 3.131 N/A ALA 144.A N ALA 141.A O no hydrogen 3.044 N/A PHE 145.A N LEU 142.A O no hydrogen 3.197 N/A TYR 146.A N LEU 142.A O no hydrogen 2.803 N/A ARG 154.A N ASP 150.A O no hydrogen 3.249 N/A ARG 154.A NH1 ASP 150.A O no hydrogen 3.496 N/A ARG 154.A NH1 ASP 150.A OD1 no hydrogen 3.096 N/A GLU 155.A N ARG 152.A O no hydrogen 3.085 N/A VAL 156.A N ARG 152.A O no hydrogen 2.872 N/A SER 157.A N HIS 153.A O no hydrogen 3.001 N/A SER 157.A OG HIS 153.A O no hydrogen 3.172 N/A ALA 158.A N ARG 154.A O no hydrogen 3.335 N/A ILE 159.A N GLU 155.A O no hydrogen 2.921 N/A ARG 160.A N VAL 156.A O no hydrogen 2.818 N/A ARG 160.A NH1 ASP 148.A OD1 no hydrogen 2.543 N/A ARG 160.A NH2 ASP 148.A OD1 no hydrogen 3.171 N/A ARG 160.A NH2 ASP 148.A OD2 no hydrogen 2.848 N/A MET 161.A N SER 157.A O no hydrogen 3.073 N/A ILE 162.A N ALA 158.A O no hydrogen 3.135 N/A ALA 163.A N ILE 159.A O no hydrogen 2.866 N/A LYS 164.A N ARG 160.A O no hydrogen 2.933 N/A LYS 164.A NZ HIS 111.A O no hydrogen 2.946 N/A LYS 164.A NZ MET 113.A O no hydrogen 2.649 N/A LYS 164.A NZ TYR 146.A OH no hydrogen 3.362 N/A LEU 165.A N MET 161.A O no hydrogen 3.048 N/A THR 167.A OG1 THR 112.A O no hydrogen 2.664 N/A LEU 168.A N LYS 164.A O no hydrogen 2.811 N/A VAL 169.A N LEU 165.A O no hydrogen 2.896 N/A ALA 170.A N PRO 166.A O no hydrogen 2.952 N/A MET 171.A N THR 167.A O no hydrogen 2.887 N/A ALA 172.A N LEU 168.A O no hydrogen 3.001 N/A TYR 173.A N VAL 169.A O no hydrogen 3.136 N/A LYS 174.A N ALA 170.A O no hydrogen 2.898 N/A LYS 174.A NZ GLN 179.A OE1 no hydrogen 2.711 N/A LYS 174.A NZ ALA 200.A O no hydrogen 3.071 N/A TYR 175.A N MET 171.A O no hydrogen 2.914 N/A TYR 175.A OH PHE 125.A O no hydrogen 2.693 N/A SER 176.A N ALA 172.A O no hydrogen 3.153 N/A SER 176.A OG ALA 172.A O no hydrogen 3.326 N/A SER 176.A OG TYR 173.A O no hydrogen 2.549 N/A ILE 177.A N TYR 173.A O no hydrogen 3.250 N/A ILE 177.A N LYS 174.A O no hydrogen 3.365 N/A GLY 178.A N TYR 175.A O no hydrogen 3.345 N/A GLN 179.A N LYS 174.A O no hydrogen 2.920 N/A ARG 185.A N ASN 193.A OD1 no hydrogen 2.453 N/A LEU 188.A N ARG 185.A O no hydrogen 3.264 N/A TYR 190.A OH ILE 162.A O no hydrogen 3.134 N/A SER 191.A OG ASP 217.A OD1 no hydrogen 2.817 N/A ALA 192.A N SER 189.A OG no hydrogen 3.408 N/A ASN 193.A N SER 189.A O no hydrogen 2.814 N/A PHE 194.A N TYR 190.A O no hydrogen 3.198 N/A MET 195.A N SER 191.A O no hydrogen 3.041 N/A ARG 196.A N ALA 192.A O no hydrogen 3.126 N/A MET 197.A N ASN 193.A O no hydrogen 2.957 N/A MET 198.A N PHE 194.A O no hydrogen 2.946 N/A PHE 199.A N MET 195.A O no hydrogen 3.059 N/A ALA 200.A N ARG 196.A O no hydrogen 2.835 N/A CYS 203.A N ASN 201.A OD1 no hydrogen 3.200 N/A GLU 204.A N ASN 201.A O no hydrogen 3.354 N/A ASN 209.A ND2 GLU 302.A OE2 no hydrogen 3.050 N/A VAL 211.A N ASN 209.A OD1 no hydrogen 3.038 N/A VAL 213.A N ASN 209.A O no hydrogen 2.937 N/A ARG 214.A N ASP 210.A O no hydrogen 2.895 N/A ARG 214.A NE ASP 210.A OD2 no hydrogen 2.898 N/A ARG 214.A NH1 GLU 298.A OE1 no hydrogen 3.101 N/A ARG 214.A NH2 GLU 298.A OE2 no hydrogen 2.479 N/A ALA 215.A N VAL 211.A O no hydrogen 3.127 N/A LEU 216.A N LEU 212.A O no hydrogen 2.975 N/A ASP 217.A N VAL 213.A O no hydrogen 2.869 N/A ARG 218.A N ARG 214.A O no hydrogen 2.966 N/A ARG 218.A NH1 LEU 291.A O no hydrogen 3.026 N/A ILE 219.A N ALA 215.A O no hydrogen 3.208 N/A LEU 220.A N LEU 216.A O no hydrogen 3.065 N/A ILE 221.A N ASP 217.A O no hydrogen 3.111 N/A LEU 222.A N ARG 218.A O no hydrogen 3.007 N/A HIS 223.A N LEU 220.A O no hydrogen 3.263 N/A HIS 223.A ND1 ILE 219.A O no hydrogen 2.690 N/A ALA 224.A N ILE 221.A O no hydrogen 3.279 N/A ASP 225.A N TYR 69.A OH no hydrogen 3.292 N/A GLU 227.A N ASP 225.A OD2 no hydrogen 2.935 N/A GLN 228.A N GLU 227.A OE1 no hydrogen 2.886 N/A GLN 228.A NE2 GLN 357.A OE1 no hydrogen 3.083 N/A ASN 229.A ND2 HIS 226.A O no hydrogen 3.097 N/A SER 231.A OG ASN 229.A OD1 no hydrogen 2.715 N/A THR 232.A N ASN 229.A OD1 no hydrogen 2.822 N/A THR 232.A OG1 GLU 227.A O no hydrogen 3.341 N/A THR 232.A OG1 ASN 229.A OD1 no hydrogen 3.200 N/A SER 233.A N ASN 229.A O no hydrogen 2.798 N/A SER 233.A OG ASN 229.A O no hydrogen 2.878 N/A THR 234.A N ALA 230.A O no hydrogen 3.197 N/A THR 234.A OG1 ALA 230.A O no hydrogen 2.726 N/A VAL 235.A N SER 231.A O no hydrogen 3.037 N/A ARG 236.A N THR 232.A O no hydrogen 3.010 N/A ARG 236.A NE GLN 357.A OE1 no hydrogen 2.891 N/A ARG 236.A NH2 GLN 357.A OE1 no hydrogen 2.665 N/A ARG 236.A NH2 GLU 360.A OE1 no hydrogen 2.553 N/A LEU 237.A N SER 233.A O no hydrogen 2.715 N/A ALA 238.A N THR 234.A O no hydrogen 2.880 N/A GLY 239.A N VAL 235.A O no hydrogen 2.965 N/A SER 240.A N ARG 236.A O no hydrogen 2.935 N/A SER 240.A N LEU 237.A O no hydrogen 3.291 N/A SER 240.A OG LEU 237.A O no hydrogen 2.427 N/A SER 241.A N ALA 238.A O no hydrogen 3.361 N/A SER 241.A OG ALA 238.A O no hydrogen 2.611 N/A GLY 242.A N GLY 239.A O no hydrogen 2.905 N/A ALA 247.A N ASN 244.A OD1 no hydrogen 2.785 N/A CYS 248.A N ASN 244.A O no hydrogen 3.064 N/A CYS 248.A SG ALA 243.A O no hydrogen 3.340 N/A CYS 248.A SG ASN 244.A O no hydrogen 3.291 N/A ILE 249.A N PRO 245.A O no hydrogen 3.048 N/A ALA 250.A N PHE 246.A O no hydrogen 3.002 N/A ALA 251.A N ALA 247.A O no hydrogen 2.765 N/A GLY 252.A N CYS 248.A O no hydrogen 2.909 N/A ILE 253.A N ILE 249.A O no hydrogen 2.870 N/A ALA 254.A N ALA 250.A O no hydrogen 3.100 N/A CYS 255.A N ALA 251.A O no hydrogen 3.309 N/A LEU 256.A N GLY 252.A O no hydrogen 2.903 N/A TRP 257.A N ILE 253.A O no hydrogen 2.992 N/A ALA 265.A N GLY 261.A O no hydrogen 2.982 N/A ALA 266.A N ALA 262.A O no hydrogen 3.246 N/A LEU 267.A N ASN 263.A O no hydrogen 3.174 N/A ASN 268.A N GLU 264.A O no hydrogen 2.748 N/A MET 269.A N ALA 265.A O no hydrogen 3.348 N/A LEU 270.A N ALA 266.A O no hydrogen 3.353 N/A GLU 271.A N LEU 267.A O no hydrogen 3.028 N/A GLN 272.A N MET 269.A O no hydrogen 3.284 N/A ILE 273.A N LEU 270.A O no hydrogen 3.180 N/A GLU 281.A N ASP 277.A O no hydrogen 2.632 N/A PHE 282.A N ASN 278.A O no hydrogen 3.329 N/A ILE 283.A N ILE 279.A O no hydrogen 2.863 N/A LYS 284.A N PRO 280.A O no hydrogen 2.768 N/A ARG 288.A N ASP 286.A OD1 no hydrogen 3.013 N/A ARG 288.A NE ASP 286.A OD1 no hydrogen 3.444 N/A ARG 288.A NH1 LEU 222.A O no hydrogen 2.831 N/A ALA 289.A N ASP 286.A O no hydrogen 3.118 N/A MET 292.A N ARG 288.A O no hydrogen 3.020 N/A ARG 293.A N ALA 289.A O no hydrogen 2.902 N/A GLU 294.A N LYS 290.A O no hydrogen 3.157 N/A THR 295.A N LEU 291.A O no hydrogen 2.866 N/A THR 295.A OG1 LEU 291.A O no hydrogen 3.061 N/A CYS 296.A N MET 292.A O no hydrogen 2.756 N/A TYR 297.A N ARG 293.A O no hydrogen 2.925 N/A GLU 298.A N GLU 294.A O no hydrogen 3.024 N/A VAL 299.A N THR 295.A O no hydrogen 3.001 N/A LEU 300.A N CYS 296.A O no hydrogen 3.229 N/A ASN 301.A N TYR 297.A O no hydrogen 3.108 N/A GLU 302.A N GLU 298.A O no hydrogen 2.897 N/A LEU 303.A N VAL 299.A O no hydrogen 2.959 N/A GLY 304.A N ASN 301.A O no hydrogen 3.307 N/A LEU 305.A N LEU 300.A O no hydrogen 2.794 N/A PHE 311.A N ASP 308.A O no hydrogen 3.237 N/A LYS 312.A N PRO 309.A O no hydrogen 3.432 N/A LEU 313.A N LEU 310.A O no hydrogen 3.143 N/A ALA 314.A N LEU 310.A O no hydrogen 3.442 N/A MET 315.A N PHE 311.A O no hydrogen 2.838 N/A GLN 316.A N LYS 312.A O no hydrogen 2.925 N/A LEU 317.A N LEU 313.A O no hydrogen 2.962 N/A GLU 318.A N MET 315.A O no hydrogen 3.299 N/A LYS 319.A N MET 315.A O no hydrogen 3.178 N/A PHE 326.A N ASN 323.A O no hydrogen 3.147 N/A PHE 326.A N ASN 323.A OD1 no hydrogen 3.021 N/A SER 328.A N VAL 324.A O no hydrogen 2.948 N/A SER 328.A OG VAL 324.A O no hydrogen 2.772 N/A GLY 329.A N ASP 325.A O no hydrogen 3.276 N/A ILE 330.A N PHE 326.A O no hydrogen 3.445 N/A VAL 331.A N TYR 327.A O no hydrogen 2.857 N/A GLN 332.A N SER 328.A O no hydrogen 2.958 N/A GLN 332.A NE2 ASN 263.A OD1 no hydrogen 3.437 N/A ARG 333.A N GLY 329.A O no hydrogen 3.235 N/A ALA 334.A N ILE 330.A O no hydrogen 2.949 N/A LEU 335.A N VAL 331.A O no hydrogen 2.845 N/A LEU 335.A N GLN 332.A O no hydrogen 3.208 N/A GLY 336.A N ARG 333.A O no hydrogen 3.219 N/A ILE 337.A N GLN 332.A O no hydrogen 2.929 N/A MET 341.A N PRO 338.A O no hydrogen 2.952 N/A PHE 342.A N THR 339.A O no hydrogen 3.267 N/A ILE 345.A N MET 341.A O no hydrogen 2.986 N/A PHE 346.A N PHE 342.A O no hydrogen 3.126 N/A ALA 347.A N THR 343.A O no hydrogen 2.943 N/A MET 348.A N CYS 344.A O no hydrogen 3.000 N/A ALA 349.A N ILE 345.A O no hydrogen 3.165 N/A ALA 349.A N PHE 346.A O no hydrogen 3.257 N/A ARG 350.A N PHE 346.A O no hydrogen 2.989 N/A ARG 350.A NE HIS 223.A O no hydrogen 2.959 N/A THR 351.A OG1 ALA 347.A O no hydrogen 2.597 N/A TRP 354.A N ARG 350.A O no hydrogen 2.972 N/A ILE 355.A N THR 351.A O no hydrogen 2.986 N/A ALA 356.A N VAL 352.A O no hydrogen 3.002 N/A GLN 357.A N GLY 353.A O no hydrogen 2.837 N/A GLN 357.A NE2 ASP 225.A OD1 no hydrogen 3.439 N/A GLN 357.A NE2 ASP 225.A OD2 no hydrogen 3.351 N/A TRP 358.A N TRP 354.A O no hydrogen 2.800 N/A ASN 359.A N ILE 355.A O no hydrogen 2.788 N/A GLU 360.A N ALA 356.A O no hydrogen 3.020 N/A MET 361.A N GLN 357.A O no hydrogen 3.033 N/A ILE 362.A N TRP 358.A O no hydrogen 2.960 N/A ALA 363.A N ASN 359.A O no hydrogen 2.963 N/A ASP 364.A N GLU 360.A O no hydrogen 3.010 N/A GLU 366.A N ASP 364.A OD1 no hydrogen 2.752 N/A GLN 367.A N ASP 364.A O no hydrogen 3.103 N/A GLN 367.A NE2 SER 240.A O no hydrogen 3.105 N/A GLY 370.A N SER 240.A OG no hydrogen 3.162 N/A ARG 371.A NH1 PRO 372.A O no hydrogen 3.179 N/A GLN 389.A N PRO 386.A O no hydrogen 2.789 N/A ARG 390.A N ILE 387.A O no hydrogen 3.237 N/A ARG 390.A NE LYS 385.A O no hydrogen 2.864 N/A ARG 390.A NH2 LYS 385.A O no hydrogen 2.927 N/A