Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4xnz_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 2.A N VAL 337.A O no hydrogen 3.108 N/A CYS 8.A SG ALA 27.A O no hydrogen 3.286 N/A ALA 9.A N HIS 97.A O no hydrogen 2.670 N/A SER 10.A N VAL 29.A O no hydrogen 2.976 N/A LYS 13.A N ASN 21.A OD1 no hydrogen 3.237 N/A LYS 13.A NZ ASP 11.A O no hydrogen 2.483 N/A VAL 19.A N SER 90.A O no hydrogen 3.206 N/A HIS 20.A N GLU 18.A OE2 no hydrogen 3.021 N/A HIS 20.A ND1 GLU 18.A OE2 no hydrogen 2.648 N/A ASN 21.A N GLU 18.A OE1 no hydrogen 2.730 N/A ASN 21.A ND2 GLU 18.A OE1 no hydrogen 2.415 N/A VAL 22.A N GLU 18.A O no hydrogen 3.054 N/A TRP 23.A N VAL 19.A O no hydrogen 3.045 N/A ALA 24.A N HIS 20.A O no hydrogen 3.096 N/A THR 25.A OG1 ASN 21.A O no hydrogen 2.427 N/A HIS 26.A N TRP 23.A O no hydrogen 3.336 N/A ALA 27.A N TRP 23.A O no hydrogen 2.969 N/A CYS 28.A N ALA 24.A O no hydrogen 3.259 N/A VAL 29.A N CYS 8.A O no hydrogen 2.949 N/A THR 31.A OG1 ASP 11.A OD1 no hydrogen 2.715 N/A ASN 34.A N ASP 32.A OD1 no hydrogen 3.100 N/A ILE 38.A N SER 125.A O no hydrogen 3.349 N/A HIS 39.A ND1 VAL 123.A O no hydrogen 2.749 N/A GLU 45.A N CYS 120.A O no hydrogen 3.160 N/A TRP 50.A N ASN 48.A OD1 no hydrogen 3.167 N/A LYS 51.A N ASN 48.A OD1 no hydrogen 3.181 N/A ASN 52.A ND2 TYR 335.A O no hydrogen 2.469 N/A MET 54.A N ASN 52.A OD1 no hydrogen 3.137 N/A VAL 55.A N ASN 52.A O no hydrogen 3.368 N/A GLU 56.A N ASN 53.A O no hydrogen 3.170 N/A GLU 60.A N GLU 56.A O no hydrogen 3.083 N/A ASP 61.A N GLN 57.A O no hydrogen 3.187 N/A VAL 62.A N MET 58.A O no hydrogen 2.983 N/A ILE 63.A N GLN 59.A O no hydrogen 3.122 N/A SER 64.A N GLU 60.A O no hydrogen 3.114 N/A SER 64.A OG GLU 60.A O no hydrogen 2.694 N/A LEU 65.A N ASP 61.A O no hydrogen 2.722 N/A TRP 66.A N VAL 62.A O no hydrogen 3.071 N/A ASP 67.A N ILE 63.A O no hydrogen 3.058 N/A GLN 68.A N SER 64.A O no hydrogen 3.326 N/A SER 69.A N LEU 65.A O no hydrogen 3.272 N/A SER 69.A OG LEU 65.A O no hydrogen 2.758 N/A LEU 70.A N SER 69.A OG no hydrogen 2.686 N/A CYS 73.A N MET 283.A O no hydrogen 2.838 N/A THR 77.A N SER 80.A O no hydrogen 3.255 N/A THR 77.A OG1 THR 77.A O no hydrogen 2.441 N/A VAL 81.A N SER 80.A OG no hydrogen 2.580 N/A ILE 82.A N LYS 75.A O no hydrogen 2.440 N/A GLN 84.A N CYS 73.A O no hydrogen 2.659 N/A LYS 88.A NZ GLU 237.A OE2 no hydrogen 2.894 N/A ASP 92.A N GLU 18.A OE2 no hydrogen 2.934 N/A ILE 96.A N ILE 132.A O no hydrogen 2.925 N/A HIS 97.A N ALA 9.A O no hydrogen 2.801 N/A HIS 97.A ND1 THR 129.A O no hydrogen 2.650 N/A TYR 98.A N THR 129.A OG1 no hydrogen 2.694 N/A TYR 98.A OH ASP 61.A OD2 no hydrogen 2.576 N/A CYS 99.A N PHE 7.A O no hydrogen 2.982 N/A THR 100.A N GLN 127.A O no hydrogen 3.132 N/A THR 100.A OG1 PRO 101.A O no hydrogen 3.298 N/A VAL 105.A N VAL 338.A O no hydrogen 3.004 N/A LEU 107.A N LYS 336.A O no hydrogen 2.837 N/A LYS 108.A N SER 124.A O no hydrogen 2.730 N/A LYS 108.A NZ ASN 110.A OD1 no hydrogen 2.561 N/A CYS 109.A N LYS 334.A O no hydrogen 3.028 N/A ASN 110.A N ASN 122.A O no hydrogen 3.192 N/A PHE 114.A N LYS 112.A O no hydrogen 2.705 N/A THR 117.A N ASN 115.A OD1 no hydrogen 3.113 N/A THR 117.A OG1 ASN 115.A OD1 no hydrogen 3.477 N/A CYS 120.A N GLU 45.A O no hydrogen 2.680 N/A CYS 120.A SG ASN 122.A O no hydrogen 3.178 N/A SER 124.A N LYS 108.A O no hydrogen 3.321 N/A SER 124.A OG HIS 39.A ND1 no hydrogen 3.365 N/A SER 125.A N ILE 38.A O no hydrogen 3.477 N/A SER 125.A OG ILE 38.A O no hydrogen 2.988 N/A VAL 126.A N ILE 106.A O no hydrogen 2.823 N/A GLN 127.A NE2 THR 100.A O no hydrogen 3.643 N/A THR 129.A N TYR 98.A O no hydrogen 3.042 N/A THR 129.A OG1 TYR 98.A O no hydrogen 3.523 N/A THR 129.A OG1 HIS 130.A O no hydrogen 3.564 N/A HIS 130.A ND1 TYR 335.A OH no hydrogen 2.776 N/A HIS 130.A NE2 GLU 331.A OE1 no hydrogen 2.770 N/A LYS 133.A NZ PRO 93.A O no hydrogen 2.303 N/A VAL 135.A N LYS 133.A O no hydrogen 2.792 N/A SER 137.A OG LEU 140.A O no hydrogen 3.011 N/A THR 138.A N HIS 231.A O no hydrogen 3.056 N/A THR 138.A OG1 GLU 226.A O no hydrogen 2.942 N/A THR 138.A OG1 MET 229.A O no hydrogen 3.294 N/A GLN 139.A NE2 ILE 227.A O no hydrogen 3.149 N/A GLN 139.A NE2 THR 228.A O no hydrogen 2.685 N/A GLN 139.A NE2 MET 229.A O no hydrogen 2.898 N/A LEU 140.A N THR 138.A O no hydrogen 2.430 N/A LEU 141.A N GLY 300.A O no hydrogen 2.553 N/A ASN 143.A N ASN 297.A O no hydrogen 3.276 N/A SER 145.A N GLU 331.A OE2 no hydrogen 2.765 N/A SER 145.A OG GLU 331.A OE1 no hydrogen 2.813 N/A ALA 147.A N LEU 169.A O no hydrogen 2.634 N/A ILE 152.A N HIS 168.A O no hydrogen 3.337 N/A ARG 154.A N ILE 166.A O no hydrogen 2.760 N/A ARG 154.A NH2 PHE 114.A O no hydrogen 2.604 N/A ARG 154.A NH2 ASN 115.A O no hydrogen 2.932 N/A ASN 157.A N SER 155.A OG no hydrogen 3.397 N/A ASN 157.A ND2 GLU 156.A O no hydrogen 2.848 N/A ASN 160.A N ASN 157.A O no hydrogen 3.126 N/A ALA 162.A N ASN 160.A OD1 no hydrogen 2.977 N/A LYS 163.A N ASN 160.A O no hydrogen 3.221 N/A LYS 163.A NZ GLU 156.A OE1 no hydrogen 3.287 N/A ILE 165.A N LEU 303.A O no hydrogen 3.279 N/A ILE 166.A N ARG 154.A O no hydrogen 2.490 N/A VAL 167.A N ILE 301.A O no hydrogen 3.246 N/A HIS 168.A N ILE 152.A O no hydrogen 3.066 N/A LEU 169.A N THR 299.A O no hydrogen 2.895 N/A ASN 170.A ND2 GLU 149.A O no hydrogen 2.716 N/A SER 172.A OG ILE 298.A O no hydrogen 2.708 N/A ILE 175.A N SER 296.A O no hydrogen 2.876 N/A ASN 176.A N ASN 176.A OD1 no hydrogen 2.516 N/A ASN 176.A N GLU 189.A O no hydrogen 3.325 N/A CYS 177.A N CYS 294.A O no hydrogen 2.976 N/A THR 178.A N TYR 187.A O no hydrogen 2.708 N/A THR 178.A OG1 ASN 293.A OD1 no hydrogen 2.876 N/A ARG 179.A N ILE 292.A O no hydrogen 2.859 N/A ARG 179.A NE ARG 179.A O no hydrogen 3.233 N/A ARG 179.A NH2 GLY 290.A O no hydrogen 3.537 N/A ALA 186.A N CYS 267.A O no hydrogen 3.270 N/A TYR 187.A N THR 178.A O no hydrogen 3.154 N/A CYS 188.A N LEU 265.A O no hydrogen 3.072 N/A GLU 189.A N ASN 176.A O no hydrogen 3.416 N/A ILE 190.A N ILE 263.A O no hydrogen 2.846 N/A THR 193.A N ASN 191.A OD1 no hydrogen 3.246 N/A THR 193.A OG1 ASN 191.A OD1 no hydrogen 2.850 N/A LYS 194.A N ASN 191.A O no hydrogen 3.138 N/A LYS 194.A NZ SER 172.A O no hydrogen 2.913 N/A TRP 195.A N ASN 191.A O no hydrogen 2.805 N/A TRP 195.A NE1 LEU 246.A O no hydrogen 3.184 N/A ASN 196.A N GLY 192.A O no hydrogen 3.108 N/A ASN 196.A ND2 THR 256.A OG1 no hydrogen 3.158 N/A VAL 198.A N LYS 194.A O no hydrogen 2.948 N/A LEU 199.A N TRP 195.A O no hydrogen 2.843 N/A LYS 200.A N ASN 196.A O no hydrogen 3.100 N/A GLN 201.A N LYS 197.A O no hydrogen 3.098 N/A VAL 202.A N VAL 198.A O no hydrogen 3.086 N/A THR 203.A N LEU 199.A O no hydrogen 3.271 N/A THR 203.A OG1 LYS 200.A O no hydrogen 2.414 N/A GLU 204.A N LYS 200.A O no hydrogen 3.186 N/A LYS 205.A NZ GLU 208.A OE1 no hydrogen 3.475 N/A LEU 206.A N VAL 202.A O no hydrogen 2.901 N/A LYS 207.A N THR 203.A O no hydrogen 2.537 N/A HIS 209.A N LEU 206.A O no hydrogen 3.241 N/A LYS 213.A N PHE 210.A O no hydrogen 2.754 N/A LYS 213.A NZ GLU 315.A OE2 no hydrogen 3.444 N/A THR 214.A OG1 SER 313.A O no hydrogen 2.820 N/A ILE 216.A N GLU 315.A O no hydrogen 2.777 N/A PHE 217.A N ASN 249.A O no hydrogen 2.920 N/A GLN 218.A N PHE 317.A O no hydrogen 3.286 N/A ILE 227.A N ASP 224.A O no hydrogen 3.248 N/A THR 228.A N ASP 224.A O no hydrogen 3.096 N/A THR 228.A OG1 GLY 223.A O no hydrogen 3.452 N/A THR 228.A OG1 ASP 224.A O no hydrogen 2.888 N/A MET 229.A N LEU 225.A O no hydrogen 3.343 N/A HIS 230.A N CYS 241.A O no hydrogen 3.000 N/A HIS 231.A N THR 138.A OG1 no hydrogen 2.988 N/A PHE 232.A N PHE 239.A O no hydrogen 3.385 N/A CYS 234.A N GLU 237.A O no hydrogen 3.113 N/A GLU 237.A N CYS 234.A O no hydrogen 2.958 N/A PHE 239.A N PHE 232.A O no hydrogen 3.086 N/A TYR 240.A N LYS 268.A O no hydrogen 3.032 N/A ASN 242.A N PRO 266.A O no hydrogen 2.638 N/A THR 243.A OG1 THR 243.A O no hydrogen 2.370 N/A THR 244.A N ASN 242.A OD1 no hydrogen 3.037 N/A THR 244.A OG1 ASN 242.A OD1 no hydrogen 3.015 N/A LEU 246.A N THR 243.A O no hydrogen 3.394 N/A THR 250.A N GLU 255.A O no hydrogen 3.061 N/A CYS 251.A N ILE 215.A O no hydrogen 2.998 N/A CYS 251.A SG ILE 215.A O no hydrogen 3.238 N/A ASN 254.A ND2 ASN 196.A O no hydrogen 2.421 N/A GLU 255.A N THR 250.A O no hydrogen 2.835 N/A LEU 265.A N CYS 188.A O no hydrogen 2.753 N/A CYS 267.A N ALA 186.A O no hydrogen 2.819 N/A CYS 267.A SG LEU 265.A O no hydrogen 3.196 N/A LYS 268.A N TYR 240.A O no hydrogen 2.870 N/A ILE 269.A N ARG 184.A O no hydrogen 3.328 N/A LYS 270.A N PHE 238.A O no hydrogen 3.270 N/A ILE 273.A N ALA 282.A O no hydrogen 2.496 N/A ASN 274.A N GLU 226.A OE2 no hydrogen 3.435 N/A ASN 274.A ND2 GLU 226.A OE2 no hydrogen 3.254 N/A MET 275.A N GLY 280.A O no hydrogen 2.900 N/A GLY 278.A N MET 275.A O no hydrogen 3.437 N/A ALA 282.A N ILE 273.A O no hydrogen 2.315 N/A TYR 284.A N GLN 271.A O no hydrogen 2.831 N/A ILE 292.A N ARG 179.A O no hydrogen 3.166 N/A CYS 294.A N CYS 177.A O no hydrogen 2.789 N/A SER 296.A N ILE 175.A O no hydrogen 3.251 N/A SER 296.A OG ASN 143.A OD1 no hydrogen 2.863 N/A ILE 298.A N VAL 173.A O no hydrogen 2.808 N/A THR 299.A N LEU 141.A O no hydrogen 3.007 N/A THR 299.A OG1 SER 145.A O no hydrogen 2.371 N/A ILE 301.A N VAL 167.A O no hydrogen 3.320 N/A LEU 302.A N GLN 139.A O no hydrogen 2.613 N/A LEU 303.A N ILE 165.A O no hydrogen 3.383 N/A THR 304.A N ARG 318.A O no hydrogen 2.499 N/A ARG 305.A NH1 LEU 158.A O no hydrogen 2.477 N/A ASP 306.A N THR 316.A O no hydrogen 2.855 N/A THR 312.A OG1 ASN 311.A OD1 no hydrogen 3.098 N/A GLU 315.A N THR 214.A O no hydrogen 2.733 N/A PHE 317.A N ILE 216.A O no hydrogen 3.004 N/A ARG 318.A N THR 304.A O no hydrogen 3.269 N/A ARG 318.A NH1 PRO 219.A O no hydrogen 2.799 N/A GLY 320.A N LEU 302.A O no hydrogen 2.675 N/A ASP 326.A N ASN 323.A O no hydrogen 3.044 N/A ASN 327.A ND2 SER 137.A O no hydrogen 3.378 N/A TRP 328.A NE1 GLN 59.A OE1 no hydrogen 2.834 N/A ARG 329.A N LYS 325.A O no hydrogen 3.314 N/A ARG 329.A NE MET 49.A O no hydrogen 2.925 N/A SER 330.A OG ASP 326.A O no hydrogen 3.171 N/A SER 330.A OG ASN 327.A O no hydrogen 3.396 N/A GLU 331.A N TRP 328.A O no hydrogen 3.267 N/A LEU 332.A N TRP 328.A O no hydrogen 3.077 N/A TYR 335.A N LEU 332.A O no hydrogen 3.378 N/A TYR 335.A OH HIS 130.A ND1 no hydrogen 2.776 N/A LYS 336.A N LEU 107.A O no hydrogen 3.172 N/A LYS 336.A NZ ASP 1.A OD1 no hydrogen 2.823 N/A LYS 336.A NZ GLU 45.A OE2 no hydrogen 3.067 N/A LYS 336.A NZ ASN 46.A O no hydrogen 2.312 N/A VAL 338.A N VAL 105.A O no hydrogen 3.107 N/A ILE 340.A N GLY 103.A O no hydrogen 2.993 N/A