Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4xo7_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 4.A OH ASP 77.A OD1 no hydrogen 3.102 N/A CYS 6.A SG.B TYR 4.A O no hydrogen 4.010 N/A VAL 7.A N MET 15.A O no hydrogen 2.827 N/A LEU 9.A N HIS 13.A O no hydrogen 2.731 N/A ASN 10.A ND2 PRO 185.A O no hydrogen 3.049 N/A ASN 10.A ND2 ASP 209.A O no hydrogen 2.893 N/A GLY 12.A N LEU 9.A O no hydrogen 2.975 N/A HIS 13.A N ASP 11.A OD1 no hydrogen 3.032 N/A MET 15.A N VAL 7.A O no hydrogen 2.904 N/A VAL 17.A N GLN 5.A O no hydrogen 2.946 N/A GLY 19.A N VAL 266.A O no hydrogen 2.833 N/A PHE 20.A N HIS 47.A O no hydrogen 2.689 N/A GLY 21.A N ALA 268.A O no hydrogen 3.063 N/A THR 22.A OG1 ASP 49.A O no hydrogen 2.719 N/A THR 22.A OG1 ASN 56.A OD1 no hydrogen 3.261 N/A TYR 23.A OH GLU 223.A OE1 no hydrogen 2.558 N/A ALA 26.A N GLU 223.A OE2 no hydrogen 3.038 N/A GLU 27.A N GLU 27.A OE1 no hydrogen 2.922 N/A VAL 28.A N PRO 25.A O no hydrogen 2.927 N/A LYS 30.A NZ ASN 55.A O no hydrogen 3.094 N/A ALA 33.A N LYS 30.A O no hydrogen 2.824 N/A GLU 35.A N SER 31.A O no hydrogen 3.097 N/A ALA 36.A N LYS 32.A O no hydrogen 3.067 N/A VAL 37.A N ALA 33.A O no hydrogen 2.823 N/A LYS 38.A N LEU 34.A O no hydrogen 3.060 N/A LEU 39.A N GLU 35.A O no hydrogen 2.879 N/A ALA 40.A N ALA 36.A O no hydrogen 2.906 N/A ILE 41.A N VAL 37.A O no hydrogen 3.035 N/A GLU 42.A N LYS 38.A O no hydrogen 2.952 N/A ALA 43.A N LEU 39.A O no hydrogen 2.942 N/A ALA 43.A N ALA 40.A O no hydrogen 3.041 N/A GLY 44.A N ALA 40.A O no hydrogen 3.125 N/A GLY 44.A N ILE 41.A O no hydrogen 3.109 N/A PHE 45.A N ALA 40.A O no hydrogen 2.962 N/A HIS 46.A ND1 ASP 77.A O no hydrogen 2.851 N/A HIS 47.A ND1 PRO 16.A O no hydrogen 2.965 N/A ILE 48.A N PHE 79.A O no hydrogen 2.823 N/A ASP 49.A N PHE 20.A O no hydrogen 2.823 N/A SER 50.A N THR 81.A O no hydrogen 2.956 N/A SER 50.A OG THR 22.A OG1 no hydrogen 3.284 N/A HIS 52.A N LYS 83.A O no hydrogen 3.496 N/A TYR 54.A N ALA 51.A O no hydrogen 3.151 N/A ASN 55.A N HIS 52.A O no hydrogen 3.197 N/A ASN 56.A ND2 SER 50.A OG no hydrogen 2.660 N/A VAL 60.A N ASN 56.A O no hydrogen 2.828 N/A GLY 61.A N GLU 57.A O no hydrogen 2.883 N/A LEU 62.A N GLU 58.A O no hydrogen 3.133 N/A ALA 63.A N GLN 59.A O no hydrogen 2.950 N/A ILE 64.A N VAL 60.A O no hydrogen 3.053 N/A ARG 65.A N GLY 61.A O no hydrogen 2.879 N/A ARG 65.A NE LEU 105.A O no hydrogen 2.912 N/A SER 66.A N LEU 62.A O no hydrogen 2.730 N/A LYS 67.A N ALA 63.A O no hydrogen 2.959 N/A LYS 67.A NZ GLU 42.A OE2 no hydrogen 2.618 N/A LYS 67.A NZ ASP 70.A OD2 no hydrogen 3.135 N/A ILE 68.A N ILE 64.A O no hydrogen 2.989 N/A ALA 69.A N ARG 65.A O no hydrogen 2.860 N/A ASP 70.A N SER 66.A O no hydrogen 2.941 N/A GLY 71.A N ILE 68.A O no hydrogen 3.063 N/A SER 72.A N LYS 67.A O no hydrogen 2.993 N/A SER 72.A N ASP 70.A OD1 no hydrogen 2.885 N/A SER 72.A OG GLU 42.A OE2 no hydrogen 3.222 N/A SER 72.A OG ASP 70.A OD1 no hydrogen 2.600 N/A VAL 73.A N LYS 67.A O no hydrogen 3.182 N/A ARG 75.A NH1 ARG 75.A O no hydrogen 3.048 N/A ARG 75.A NH1 ASP 111.A OD2 no hydrogen 2.868 N/A ARG 75.A NH2 TYR 109.A O no hydrogen 2.952 N/A ARG 75.A NH2 ASP 111.A OD2 no hydrogen 2.943 N/A ASP 77.A N LYS 74.A O no hydrogen 2.847 N/A ILE 78.A N ARG 75.A O no hydrogen 3.063 N/A PHE 79.A N HIS 46.A O no hydrogen 2.660 N/A TYR 80.A N ASP 111.A OD2 no hydrogen 2.775 N/A TYR 80.A OH GLU 57.A OE2 no hydrogen 2.633 N/A THR 81.A N ILE 48.A O no hydrogen 2.908 N/A SER 82.A N LEU 112.A O no hydrogen 2.893 N/A SER 82.A OG GLU 57.A OE2 no hydrogen 2.670 N/A LYS 83.A NZ ASP 49.A OD1 no hydrogen 3.488 N/A LYS 83.A NZ ASP 49.A OD2 no hydrogen 2.710 N/A LYS 83.A NZ SER 50.A O no hydrogen 2.933 N/A LYS 83.A NZ TYR 54.A OH no hydrogen 3.044 N/A LEU 84.A N LEU 114.A O no hydrogen 2.754 N/A TRP 85.A NE1 VAL 127.A O no hydrogen 2.817 N/A SER 86.A OG PHE 117.A O no hydrogen 3.337 N/A SER 86.A OG VAL 119.A O no hydrogen 3.313 N/A ASN 87.A ND2 GLY 124.A O no hydrogen 3.072 N/A ASN 87.A ND2 GLU 126.A O no hydrogen 3.447 N/A SER 88.A N TRP 85.A O no hydrogen 2.939 N/A HIS 89.A ND1 SER 120.A OG no hydrogen 2.799 N/A ARG 90.A NE ASP 139.A OD2 no hydrogen 2.701 N/A ARG 90.A NH2 ASP 139.A OD1 no hydrogen 3.080 N/A ARG 90.A NH2 ASP 139.A OD2 no hydrogen 3.419 N/A LEU 93.A N ARG 90.A O no hydrogen 2.873 N/A ARG 95.A NE GLU 99.A OE2 no hydrogen 2.907 N/A ALA 97.A N LEU 93.A O no hydrogen 3.069 N/A LEU 98.A N VAL 94.A O no hydrogen 2.974 N/A GLU 99.A N ARG 95.A O no hydrogen 2.723 N/A ARG 100.A N PRO 96.A O no hydrogen 2.863 N/A SER 101.A N ALA 97.A O no hydrogen 3.056 N/A SER 101.A OG GLU 57.A OE1 no hydrogen 2.535 N/A SER 101.A OG GLU 57.A OE2 no hydrogen 3.513 N/A LEU 102.A N LEU 98.A O no hydrogen 2.928 N/A LYS 103.A N GLU 99.A O no hydrogen 2.816 N/A ASN 104.A N ARG 100.A O no hydrogen 3.134 N/A LEU 105.A N SER 101.A O no hydrogen 2.919 N/A GLN 106.A N LYS 103.A O no hydrogen 3.252 N/A LEU 107.A N LEU 102.A O no hydrogen 3.260 N/A VAL 110.A N LEU 158.A O no hydrogen 2.901 N/A ASP 111.A N TYR 80.A O no hydrogen 2.816 N/A LEU 112.A N TYR 80.A O no hydrogen 3.125 N/A TYR 113.A N SER 161.A O no hydrogen 3.104 N/A LEU 114.A N SER 82.A O no hydrogen 3.003 N/A ILE 115.A N GLY 163.A O no hydrogen 3.152 N/A HIS 116.A N LEU 84.A O no hydrogen 3.088 N/A SER 120.A OG HIS 89.A ND1 no hydrogen 2.799 N/A VAL 121.A N SER 86.A O no hydrogen 3.121 N/A LYS 122.A N LEU 137.A O no hydrogen 2.921 N/A LYS 122.A NZ ASP 139.A OD1 no hydrogen 2.932 N/A ASP 131.A N LYS 135.A O no hydrogen 2.826 N/A GLY 134.A N ASP 131.A O no hydrogen 2.664 N/A LYS 135.A N ASP 131.A OD1 no hydrogen 2.317 N/A LEU 137.A N PRO 129.A O no hydrogen 2.853 N/A ASP 139.A N SER 120.A O no hydrogen 2.989 N/A CYS 144.A N ASP 142.A OD1 no hydrogen 2.991 N/A CYS 144.A SG MET 174.A O no hydrogen 3.704 N/A ALA 145.A N ASP 142.A O no hydrogen 2.779 N/A THR 146.A N ASP 142.A O no hydrogen 3.180 N/A THR 146.A OG1 HIS 89.A O no hydrogen 2.655 N/A TRP 147.A N LEU 143.A O no hydrogen 2.727 N/A TRP 147.A NE1 TYR 183.A O no hydrogen 2.854 N/A GLU 148.A N CYS 144.A O no hydrogen 2.963 N/A ALA 149.A N ALA 145.A O no hydrogen 3.124 N/A MET 150.A N THR 146.A O no hydrogen 3.004 N/A GLU 151.A N TRP 147.A O no hydrogen 2.851 N/A LYS 152.A N GLU 148.A O no hydrogen 3.132 N/A CYS 153.A N ALA 149.A O no hydrogen 3.144 N/A CYS 153.A SG ALA 149.A O no hydrogen 3.525 N/A LYS 154.A N MET 150.A O no hydrogen 3.057 N/A LYS 154.A NZ ASP 11.A OD2 no hydrogen 3.469 N/A LYS 154.A NZ LYS 160.A O no hydrogen 2.780 N/A ASP 155.A N GLU 151.A O no hydrogen 2.828 N/A ALA 156.A N LYS 152.A O no hydrogen 2.841 N/A GLY 157.A N LYS 154.A O no hydrogen 2.985 N/A LEU 158.A N CYS 153.A O no hydrogen 3.056 N/A ALA 159.A N CYS 153.A O no hydrogen 3.418 N/A LYS 160.A N VAL 110.A O no hydrogen 2.928 N/A LYS 160.A NZ GLY 157.A O no hydrogen 2.829 N/A SER 161.A N ASP 111.A O no hydrogen 2.930 N/A SER 161.A OG ASP 11.A OD1 no hydrogen 3.311 N/A SER 161.A OG ASP 11.A OD2 no hydrogen 2.506 N/A GLY 163.A N TYR 113.A O no hydrogen 2.986 N/A VAL 164.A N CYS 187.A O no hydrogen 3.092 N/A SER 165.A N ILE 115.A O no hydrogen 2.860 N/A SER 165.A OG ASN 166.A OD1 no hydrogen 3.309 N/A SER 165.A OG GLN 189.A O no hydrogen 2.697 N/A ASN 166.A N GLN 189.A O no hydrogen 2.877 N/A ASN 166.A ND2 TYR 215.A OH no hydrogen 2.624 N/A PHE 167.A N ASN 188.A OD1 no hydrogen 3.175 N/A ASN 168.A ND2 PRO 317.A O no hydrogen 3.083 N/A HIS 169.A N TYR 322.A O no hydrogen 2.955 N/A ARG 170.A NH2 PRO 314.A O no hydrogen 3.336 N/A ARG 170.A NH2 ASN 315.A OD1 no hydrogen 2.960 N/A LEU 171.A N ASN 168.A OD1 no hydrogen 2.854 N/A LEU 172.A N ASN 168.A O no hydrogen 2.940 N/A GLU 173.A N HIS 169.A O no hydrogen 2.946 N/A MET 174.A N ARG 170.A O no hydrogen 2.967 N/A ILE 175.A N LEU 171.A O no hydrogen 3.217 N/A LEU 176.A N LEU 172.A O no hydrogen 2.853 N/A ASN 177.A N GLU 173.A O no hydrogen 2.766 N/A LYS 178.A N ILE 175.A O no hydrogen 2.996 N/A LYS 178.A NZ GLU 148.A OE1 no hydrogen 3.074 N/A LYS 178.A NZ PRO 179.A O no hydrogen 2.795 N/A LEU 181.A N LYS 178.A O no hydrogen 3.195 N/A LYS 182.A N GLU 151.A OE2 no hydrogen 2.708 N/A LYS 182.A NZ ASP 155.A OD1 no hydrogen 3.421 N/A LYS 182.A NZ ASP 155.A OD2 no hydrogen 2.887 N/A TYR 183.A N GLU 151.A OE2 no hydrogen 2.970 N/A TYR 183.A OH ASP 155.A OD1 no hydrogen 2.601 N/A LYS 184.A NZ LYS 208.A O no hydrogen 2.612 N/A VAL 186.A N ILE 162.A O no hydrogen 2.869 N/A ASN 188.A N VAL 211.A O no hydrogen 3.030 N/A ASN 188.A ND2 PHE 167.A O no hydrogen 2.836 N/A GLN 189.A N VAL 164.A O no hydrogen 2.902 N/A GLN 189.A NE2 ASP 49.A OD1 no hydrogen 3.028 N/A VAL 190.A N VAL 213.A O no hydrogen 2.903 N/A CYS 192.A N TYR 215.A O no hydrogen 3.052 N/A CYS 192.A SG PHE 196.A O no hydrogen 3.937 N/A CYS 192.A SG ASN 197.A O no hydrogen 3.266 N/A CYS 192.A SG GLN 259.A OE1 no hydrogen 3.801 N/A HIS 193.A N PHE 196.A O no hydrogen 3.210 N/A HIS 193.A NE2 GLU 191.A OE2 no hydrogen 2.826 N/A TYR 195.A N HIS 193.A ND1 no hydrogen 2.985 N/A TYR 195.A OH ASP 237.A OD1 no hydrogen 2.565 N/A PHE 196.A N HIS 193.A O no hydrogen 2.871 N/A ASN 197.A N ASN 299.A OD1 no hydrogen 2.915 N/A GLN 198.A NE2 GLU 191.A O no hydrogen 2.790 N/A ARG 199.A N ASN 197.A OD1 no hydrogen 3.089 N/A ARG 199.A NH1 ASP 203.A OD1 no hydrogen 2.834 N/A LYS 200.A NZ GLU 321.A OE2 no hydrogen 2.543 N/A LEU 202.A N GLN 198.A O no hydrogen 2.681 N/A ASP 203.A N ARG 199.A O no hydrogen 2.870 N/A PHE 204.A N LYS 200.A O no hydrogen 2.995 N/A CYS 205.A N LEU 201.A O no hydrogen 2.894 N/A CYS 205.A SG LEU 201.A O no hydrogen 3.408 N/A LYS 206.A N LEU 202.A O no hydrogen 2.793 N/A LYS 206.A NZ ARG 262.A O no hydrogen 2.862 N/A SER 207.A N ASP 203.A O no hydrogen 2.970 N/A SER 207.A OG PHE 204.A O no hydrogen 2.764 N/A LYS 208.A N PHE 204.A O no hydrogen 3.259 N/A LYS 208.A N CYS 205.A O no hydrogen 2.966 N/A ASP 209.A N LYS 206.A O no hydrogen 3.024 N/A ILE 210.A N CYS 205.A O no hydrogen 2.836 N/A VAL 211.A N VAL 186.A O no hydrogen 3.028 N/A VAL 213.A N ASN 188.A O no hydrogen 3.032 N/A ALA 214.A N VAL 265.A O no hydrogen 2.804 N/A TYR 215.A N VAL 190.A O no hydrogen 2.953 N/A GLY 219.A N SER 216.A O no hydrogen 2.977 N/A SER 220.A OG GLY 219.A O no hydrogen 2.644 N/A ARG 222.A N SER 220.A OG no hydrogen 2.940 N/A ARG 222.A NH1 SER 231.A O no hydrogen 3.560 N/A ARG 222.A NH1 PRO 232.A O no hydrogen 3.274 N/A ARG 222.A NH2 PRO 229.A O no hydrogen 3.052 N/A ARG 222.A NH2 SER 231.A O no hydrogen 2.935 N/A GLU 223.A N HIS 221.A ND1 no hydrogen 3.007 N/A VAL 227.A N GLU 223.A O no hydrogen 2.927 N/A ASN 230.A N ASP 228.A OD1 no hydrogen 2.920 N/A SER 231.A N ASP 228.A O no hydrogen 3.037 N/A SER 231.A OG ASP 228.A O no hydrogen 2.897 N/A GLU 236.A N VAL 233.A O no hydrogen 3.104 N/A ASP 237.A N LEU 234.A O no hydrogen 2.963 N/A LEU 240.A N ASP 237.A OD2 no hydrogen 2.982 N/A CYS 241.A N ASP 237.A O no hydrogen 2.932 N/A CYS 241.A SG LEU 235.A O no hydrogen 3.593 N/A CYS 241.A SG ASP 237.A O no hydrogen 3.269 N/A ALA 242.A N PRO 238.A O no hydrogen 2.890 N/A LEU 243.A N VAL 239.A O no hydrogen 2.897 N/A ALA 244.A N LEU 240.A O no hydrogen 2.849 N/A LYS 245.A N CYS 241.A O no hydrogen 2.987 N/A LYS 246.A N ALA 242.A O no hydrogen 2.970 N/A LYS 246.A NZ GLU 291.A OE2 no hydrogen 2.752 N/A HIS 247.A N LEU 243.A O no hydrogen 3.041 N/A HIS 247.A NE2 GLU 291.A OE1 no hydrogen 3.058 N/A HIS 247.A NE2 GLU 291.A OE2 no hydrogen 2.992 N/A LYS 248.A N LYS 245.A O no hydrogen 3.216 N/A ARG 249.A N ALA 244.A O no hydrogen 2.959 N/A ARG 249.A NH1 GLN 281.A OE1 no hydrogen 2.774 N/A LEU 253.A N THR 250.A OG1 no hydrogen 3.237 N/A ILE 254.A N THR 250.A O no hydrogen 3.060 N/A ALA 255.A N PRO 251.A O no hydrogen 2.961 N/A LEU 256.A N ALA 252.A O no hydrogen 2.809 N/A ARG 257.A N LEU 253.A O no hydrogen 2.773 N/A ARG 257.A NE GLN 261.A OE1 no hydrogen 2.756 N/A ARG 257.A NH1 VAL 282.A O no hydrogen 2.920 N/A ARG 257.A NH2 GLN 261.A OE1 no hydrogen 3.523 N/A TYR 258.A N ILE 254.A O no hydrogen 2.959 N/A TYR 258.A OH ASP 296.A OD1 no hydrogen 2.773 N/A LEU 260.A N LEU 256.A O no hydrogen 3.155 N/A GLN 261.A N ARG 257.A O no hydrogen 3.023 N/A GLN 261.A NE2 LEU 287.A O no hydrogen 2.962 N/A ARG 262.A N TYR 258.A O no hydrogen 3.240 N/A ARG 262.A N GLN 259.A O no hydrogen 3.015 N/A ARG 262.A NH1 ASN 197.A O no hydrogen 2.842 N/A ARG 262.A NH1 GLN 259.A OE1 no hydrogen 3.001 N/A ARG 262.A NH2 ASN 197.A O no hydrogen 2.963 N/A GLY 263.A N LEU 260.A O no hydrogen 3.160 N/A VAL 264.A N GLN 259.A O no hydrogen 3.014 N/A VAL 265.A N LEU 212.A O no hydrogen 3.077 N/A VAL 266.A N VAL 17.A O no hydrogen 2.927 N/A LEU 267.A N ALA 214.A O no hydrogen 2.923 N/A ALA 268.A N GLY 19.A O no hydrogen 2.824 N/A SER 270.A OG ASN 272.A O no hydrogen 3.392 N/A TYR 271.A OH THR 22.A O no hydrogen 2.549 N/A ASN 272.A N SER 270.A OG no hydrogen 2.999 N/A GLN 274.A N ASN 272.A OD1 no hydrogen 2.880 N/A ARG 275.A N ASN 272.A OD1 no hydrogen 3.166 N/A ILE 276.A N ASN 272.A O no hydrogen 2.888 N/A ARG 277.A N GLU 273.A O no hydrogen 3.183 N/A ARG 277.A NH2 GLU 273.A OE2 no hydrogen 3.017 N/A GLN 278.A N GLN 274.A O no hydrogen 2.844 N/A ASN 279.A N ARG 275.A O no hydrogen 2.984 N/A GLN 281.A N GLN 278.A O no hydrogen 2.879 N/A VAL 282.A N ASN 279.A O no hydrogen 3.267 N/A GLU 284.A N GLN 281.A O no hydrogen 2.910 N/A LEU 287.A N GLN 261.A OE1 no hydrogen 2.736 N/A THR 288.A N GLU 291.A OE1 no hydrogen 2.797 N/A GLU 291.A N THR 288.A OG1 no hydrogen 3.207 N/A MET 292.A N THR 288.A O no hydrogen 2.916 N/A LYS 293.A N SER 289.A O no hydrogen 2.858 N/A ALA 294.A N GLU 290.A O no hydrogen 2.917 N/A ILE 295.A N GLU 291.A O no hydrogen 3.008 N/A ASP 296.A N MET 292.A O no hydrogen 2.899 N/A GLY 297.A N LYS 293.A O no hydrogen 3.031 N/A LEU 298.A N ILE 295.A O no hydrogen 2.975 N/A ASN 299.A N ASP 296.A O no hydrogen 3.406 N/A ARG 300.A N TYR 195.A O no hydrogen 3.057 N/A VAL 302.A N TYR 195.A O no hydrogen 3.195 N/A TYR 304.A N GLU 191.A OE2 no hydrogen 2.693 N/A TYR 304.A OH PRO 232.A O no hydrogen 2.613 N/A LEU 305.A N GLU 191.A OE1 no hydrogen 2.980 N/A PHE 310.A N LEU 307.A O no hydrogen 2.956 N/A ALA 311.A N ASP 308.A O no hydrogen 2.964 N/A ASN 315.A ND2 PRO 118.A O no hydrogen 3.230 N/A TYR 316.A N PRO 313.A O no hydrogen 2.932 N/A TYR 316.A OH THR 306.A O no hydrogen 2.587 N/A