Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4xpc_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 5.A N THR 1.A O no hydrogen 3.090 N/A PHE 6.A N LEU 3.A O no hydrogen 3.137 N/A GLN 8.A NE2 ASN 218.A OD1 no hydrogen 2.785 N/A ALA 9.A N PHE 6.A O no hydrogen 3.110 N/A TRP 10.A NE1 TRP 2.A O no hydrogen 2.892 N/A ALA 11.A N ALA 223.A O no hydrogen 2.814 N/A GLU 12.A N GLU 12.A OE1 no hydrogen 2.779 N/A THR 13.A N TRP 10.A O no hydrogen 3.120 N/A THR 13.A OG1 PRO 7.A O no hydrogen 2.639 N/A GLY 14.A N TRP 10.A O no hydrogen 2.749 N/A LEU 18.A N GLY 220.A O no hydrogen 2.830 N/A ALA 19.A N CYS 129.A O no hydrogen 2.708 N/A VAL 20.A N LEU 219.A O no hydrogen 3.287 N/A GLN 22.A N ALA 19.A O no hydrogen 3.151 N/A GLN 22.A NE2 ASP 175.A OD1 no hydrogen 2.844 N/A LEU 25.A N ARG 131.A O no hydrogen 2.855 N/A ILE 27.A N SER 136.A OG no hydrogen 2.814 N/A LYS 30.A N ARG 93.A O no hydrogen 2.943 N/A LYS 30.A NZ LYS 92.A O no hydrogen 2.962 N/A SER 33.A N LYS 30.A O no hydrogen 3.162 N/A SER 33.A OG LYS 30.A O no hydrogen 3.555 N/A SER 33.A OG ARG 93.A O no hydrogen 2.735 N/A ILE 38.A N ASN 72.A O no hydrogen 2.800 N/A GLN 40.A NE2 TYR 41.A O no hydrogen 2.971 N/A GLN 40.A NE2 LEU 75.A O no hydrogen 2.889 N/A ALA 47.A N SER 44.A OG no hydrogen 3.141 N/A ARG 48.A N SER 44.A O no hydrogen 2.996 N/A LEU 49.A N GLN 45.A O no hydrogen 2.820 N/A GLY 50.A N GLU 46.A O no hydrogen 3.052 N/A ILE 51.A N ALA 47.A O no hydrogen 2.925 N/A LYS 52.A N ARG 48.A O no hydrogen 2.863 N/A LYS 52.A NZ ASP 146.A OD1 no hydrogen 3.003 N/A ILE 55.A N ILE 51.A O no hydrogen 3.172 N/A GLN 56.A N LYS 52.A O no hydrogen 2.917 N/A ARG 57.A N PRO 53.A O no hydrogen 3.069 N/A ARG 57.A NH1 HIS 54.A ND1 no hydrogen 3.550 N/A LEU 58.A N HIS 54.A O no hydrogen 3.037 N/A LEU 59.A N ILE 55.A O no hydrogen 2.948 N/A ASP 60.A N GLN 56.A O no hydrogen 2.849 N/A GLN 61.A N ARG 57.A O no hydrogen 2.868 N/A GLY 62.A N LEU 59.A O no hydrogen 2.937 N/A ILE 63.A N LEU 58.A O no hydrogen 2.885 N/A LEU 64.A N LEU 58.A O no hydrogen 3.177 N/A VAL 65.A N THR 153.A O no hydrogen 2.946 N/A CYS 67.A N GLN 151.A O no hydrogen 3.003 N/A SER 69.A N GLN 151.A OE1 no hydrogen 2.824 N/A SER 69.A OG TRP 71.A O no hydrogen 3.474 N/A SER 69.A OG PRO 138.A O no hydrogen 2.720 N/A TRP 71.A N SER 69.A OG no hydrogen 3.048 N/A ASN 72.A N VAL 36.A O no hydrogen 3.001 N/A ASN 72.A ND2 ILE 38.A O no hydrogen 2.905 N/A THR 73.A N ALA 141.A O no hydrogen 3.054 N/A LEU 75.A N GLN 40.A OE1 no hydrogen 2.849 N/A LEU 76.A N VAL 84.A O no hydrogen 2.770 N/A TYR 81.A OH GLU 46.A OE2 no hydrogen 3.391 N/A ARG 82.A NE PRO 83.A O no hydrogen 3.293 N/A GLN 85.A NE2 THR 73.A OG1 no hydrogen 2.883 N/A GLN 85.A NE2 PHE 140.A O no hydrogen 2.864 N/A ASP 86.A N PRO 74.A O no hydrogen 2.873 N/A ARG 88.A N ASP 86.A OD1 no hydrogen 3.116 N/A ARG 88.A NE ASP 86.A OD1 no hydrogen 2.919 N/A ARG 88.A NE ASP 86.A OD2 no hydrogen 3.480 N/A ARG 88.A NH2 ASP 86.A OD2 no hydrogen 2.934 N/A ASN 91.A N LEU 87.A O no hydrogen 2.822 N/A ASN 91.A ND2 GLY 160.A O no hydrogen 3.273 N/A LYS 92.A N ARG 88.A O no hydrogen 3.060 N/A LYS 92.A NZ GLU 89.A OE2 no hydrogen 2.898 N/A ARG 93.A N VAL 90.A O no hydrogen 2.884 N/A ARG 93.A NH1 GLU 89.A O no hydrogen 2.841 N/A ARG 93.A NH1 GLU 89.A OE1 no hydrogen 2.831 N/A VAL 94.A N ASN 91.A O no hydrogen 3.189 N/A GLU 95.A N PRO 28.A O no hydrogen 3.036 N/A THR 100.A OG1 GLU 170.A OE2 no hydrogen 2.641 N/A ASN 106.A N ASN 103.A OD1 no hydrogen 2.904 N/A LEU 107.A N ASN 103.A O no hydrogen 2.953 N/A LEU 108.A N PRO 104.A O no hydrogen 2.924 N/A SER 109.A N ASN 106.A O no hydrogen 3.190 N/A SER 109.A OG ASN 106.A O no hydrogen 2.553 N/A GLY 110.A N LEU 107.A O no hydrogen 3.203 N/A LEU 111.A N LEU 108.A O no hydrogen 3.046 N/A SER 114.A OG HIS 115.A ND1 no hydrogen 2.866 N/A HIS 115.A N PRO 112.A O no hydrogen 3.219 N/A HIS 115.A ND1 SER 114.A OG no hydrogen 2.866 N/A HIS 115.A NE2 ASP 185.A O no hydrogen 2.988 N/A GLN 116.A NE2 PRO 113.A O no hydrogen 3.255 N/A TRP 117.A N ALA 199.A O no hydrogen 3.222 N/A TYR 118.A N GLN 232.A O no hydrogen 2.734 N/A THR 119.A N LEU 197.A O no hydrogen 2.830 N/A THR 119.A OG1 THR 209.A OG1 no hydrogen 2.739 N/A VAL 120.A N GLN 229.A O no hydrogen 2.756 N/A LEU 121.A N LEU 195.A O no hydrogen 3.006 N/A LEU 123.A N ASP 193.A O no hydrogen 2.881 N/A LYS 124.A N ARG 222.A O no hydrogen 2.719 N/A LYS 124.A NZ ASP 125.A OD2 no hydrogen 3.203 N/A CYS 129.A N ALA 126.A O no hydrogen 2.934 N/A CYS 129.A SG ASP 125.A O no hydrogen 3.639 N/A CYS 129.A SG GLY 220.A O no hydrogen 3.932 N/A LEU 130.A N PHE 127.A O no hydrogen 3.036 N/A ARG 131.A NH2 GLN 22.A O no hydrogen 2.874 N/A LEU 132.A N THR 155.A O no hydrogen 2.901 N/A HIS 133.A N LEU 25.A O no hydrogen 2.787 N/A THR 135.A N HIS 133.A ND1 no hydrogen 3.030 N/A THR 135.A OG1 HIS 133.A ND1 no hydrogen 3.177 N/A SER 136.A N HIS 133.A O no hydrogen 2.943 N/A GLN 137.A N HIS 133.A O no hydrogen 3.167 N/A GLN 137.A NE2 LEU 132.A O no hydrogen 2.991 N/A LEU 139.A N SER 136.A O no hydrogen 3.226 N/A PHE 140.A N GLN 137.A O no hydrogen 3.154 N/A ALA 141.A N PRO 138.A O no hydrogen 3.397 N/A PHE 142.A N LEU 152.A O no hydrogen 2.955 N/A TRP 144.A N GLY 150.A O no hydrogen 2.814 N/A GLY 150.A N TRP 144.A O no hydrogen 3.209 N/A GLN 151.A NE2 SER 69.A O no hydrogen 3.198 N/A GLN 151.A NE2 TRP 71.A O no hydrogen 2.893 N/A GLN 151.A NE2 ASN 72.A OD1 no hydrogen 3.049 N/A LEU 152.A N PHE 142.A O no hydrogen 2.834 N/A THR 153.A N VAL 65.A O no hydrogen 2.855 N/A THR 153.A OG1 GLN 137.A O no hydrogen 2.669 N/A TRP 154.A N THR 153.A OG1 no hydrogen 2.836 N/A TRP 154.A NE1 GLN 85.A OE1 no hydrogen 2.868 N/A THR 155.A N ILE 63.A O no hydrogen 2.878 N/A THR 155.A OG1 GLY 62.A O no hydrogen 2.717 N/A THR 155.A OG1 ILE 63.A O no hydrogen 3.431 N/A ARG 156.A NH1 GLY 17.A O no hydrogen 3.216 N/A ARG 156.A NH1 PHE 128.A O no hydrogen 2.599 N/A LEU 157.A N LEU 130.A O no hydrogen 2.848 N/A LYS 162.A N ASN 91.A OD1 no hydrogen 2.870 N/A LYS 162.A NZ ASN 91.A O no hydrogen 2.921 N/A LYS 162.A NZ VAL 94.A O no hydrogen 2.808 N/A LYS 162.A NZ ASP 96.A OD1 no hydrogen 2.630 N/A ASN 163.A ND2 GLU 95.A O no hydrogen 3.478 N/A SER 164.A N PHE 161.A O no hydrogen 3.095 N/A SER 164.A OG PRO 158.A O no hydrogen 2.759 N/A LEU 167.A N ASN 163.A O no hydrogen 2.941 N/A PHE 168.A N SER 164.A O no hydrogen 2.878 N/A ASP 169.A N PRO 165.A O no hydrogen 2.975 N/A GLU 170.A N THR 166.A O no hydrogen 2.933 N/A ALA 171.A N LEU 167.A O no hydrogen 2.959 N/A LEU 172.A N PHE 168.A O no hydrogen 2.913 N/A HIS 173.A N ASP 169.A O no hydrogen 3.016 N/A ARG 174.A N GLU 170.A O no hydrogen 3.088 N/A ARG 174.A NE GLN 22.A OE1 no hydrogen 3.168 N/A ARG 174.A NH2 GLN 22.A OE1 no hydrogen 2.837 N/A ASP 175.A N ALA 171.A O no hydrogen 3.022 N/A LEU 176.A N LEU 172.A O no hydrogen 2.808 N/A LEU 176.A N HIS 173.A O no hydrogen 3.286 N/A ALA 177.A N ARG 174.A O no hydrogen 3.479 N/A ARG 180.A N LEU 176.A O no hydrogen 3.129 N/A ARG 180.A NH1 LEU 188.A O no hydrogen 2.956 N/A ARG 180.A NH2 LEU 188.A O no hydrogen 2.959 N/A ARG 180.A NH2 GLN 190.A OE1 no hydrogen 2.961 N/A ILE 181.A N ALA 177.A O no hydrogen 3.221 N/A GLN 182.A N ASP 178.A O no hydrogen 2.808 N/A GLN 182.A NE2 ASP 178.A OD1 no hydrogen 2.965 N/A HIS 183.A N PHE 179.A O no hydrogen 3.014 N/A HIS 183.A ND1 PHE 179.A O no hydrogen 3.101 N/A LEU 186.A N HIS 183.A O no hydrogen 3.168 N/A ILE 187.A N ALA 198.A O no hydrogen 2.959 N/A LEU 189.A N LEU 196.A O no hydrogen 2.810 N/A TYR 191.A N ASP 194.A O no hydrogen 2.870 N/A VAL 192.A N ASP 169.A OD1 no hydrogen 2.860 N/A ASP 194.A N TYR 191.A O no hydrogen 2.969 N/A LEU 195.A N LEU 121.A O no hydrogen 2.848 N/A LEU 196.A N LEU 189.A O no hydrogen 2.926 N/A LEU 197.A N THR 119.A O no hydrogen 2.798 N/A ALA 198.A N ILE 187.A O no hydrogen 2.787 N/A ALA 199.A N TRP 117.A O no hydrogen 2.902 N/A ASP 204.A N SER 201.A OG no hydrogen 3.142 N/A CYS 205.A N SER 201.A O no hydrogen 2.911 N/A CYS 205.A SG TRP 117.A O no hydrogen 3.582 N/A CYS 205.A SG THR 119.A OG1 no hydrogen 3.540 N/A GLN 206.A N GLU 202.A O no hydrogen 2.896 N/A GLN 207.A N LEU 203.A O no hydrogen 2.959 N/A GLY 208.A N ASP 204.A O no hydrogen 2.767 N/A THR 209.A N CYS 205.A O no hydrogen 2.869 N/A THR 209.A OG1 THR 119.A OG1 no hydrogen 2.739 N/A THR 209.A OG1 CYS 205.A O no hydrogen 2.632 N/A ARG 210.A N GLN 206.A O no hydrogen 3.011 N/A ALA 211.A N GLN 207.A O no hydrogen 3.079 N/A LEU 212.A N GLY 208.A O no hydrogen 2.837 N/A LEU 213.A N THR 209.A O no hydrogen 2.874 N/A GLN 214.A N ARG 210.A O no hydrogen 2.971 N/A GLN 214.A NE2 ASN 218.A OD1 no hydrogen 3.682 N/A THR 215.A N ALA 211.A O no hydrogen 3.009 N/A THR 215.A OG1 ALA 211.A O no hydrogen 2.834 N/A LEU 216.A N LEU 212.A O no hydrogen 2.826 N/A GLY 217.A N LEU 213.A O no hydrogen 2.942 N/A ASN 218.A N GLN 214.A O no hydrogen 2.952 N/A LEU 219.A N THR 215.A O no hydrogen 2.985 N/A GLY 220.A N LEU 216.A O no hydrogen 3.110 N/A GLY 220.A N GLY 217.A O no hydrogen 3.113 N/A TYR 221.A N LEU 216.A O no hydrogen 2.967 N/A TYR 221.A OH ASP 175.A OD2 no hydrogen 2.585 N/A ARG 222.A NE GLY 14.A O no hydrogen 3.304 N/A ARG 222.A NE GLY 15.A O no hydrogen 3.171 N/A ARG 222.A NH1 GLY 217.A O no hydrogen 3.250 N/A ARG 222.A NH1 TYR 221.A O no hydrogen 2.922 N/A ARG 222.A NH2 GLY 14.A O no hydrogen 3.328 N/A ALA 223.A N ALA 9.A O no hydrogen 2.837 N/A SER 224.A N ASP 122.A O no hydrogen 2.915 N/A ALA 225.A N GLU 12.A OE1 no hydrogen 2.899 N/A LYS 226.A N GLU 12.A OE2 no hydrogen 3.330 N/A LYS 227.A N SER 224.A OG no hydrogen 3.226 N/A GLN 229.A N VAL 120.A O no hydrogen 3.022 N/A GLN 229.A NE2 LYS 236.A O no hydrogen 2.775 N/A CYS 231.A N THR 119.A OG1 no hydrogen 3.008 N/A GLN 232.A N TYR 118.A O no hydrogen 2.819 N/A VAL 235.A N LEU 242.A O no hydrogen 3.109 N/A LYS 236.A N GLN 229.A OE1 no hydrogen 2.862 N/A TYR 237.A N TYR 240.A O no hydrogen 3.010 N/A TYR 237.A OH ASP 194.A O no hydrogen 2.845 N/A TYR 240.A N TYR 237.A O no hydrogen 3.005 N/A LEU 242.A N VAL 235.A O no hydrogen 2.741 N/A LYS 243.A N GLN 246.A O no hydrogen 3.433 N/A GLN 246.A N LYS 243.A O no hydrogen 2.967 N/A