Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4xr8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 2.A NZ THR 54.A O no hydrogen 3.077 N/A GLY 6.A N ASN 273.A OD1 no hydrogen 2.642 N/A LYS 7.A NZ.A GLU 4.A OE2 no hydrogen 2.872 N/A LEU 8.A N LYS 35.A O no hydrogen 2.966 N/A VAL 9.A N ASP 59.A OD2 no hydrogen 2.910 N/A ILE 10.A N THR 37.A O no hydrogen 2.765 N/A TRP 11.A N ILE 60.A O no hydrogen 2.815 N/A TRP 11.A NE1 GLU 39.A OE1 no hydrogen 2.827 N/A ILE 12.A N GLU 39.A O no hydrogen 2.949 N/A ASN 13.A ND2 ASP 15.A OD1 no hydrogen 2.595 N/A LYS 16.A N ASN 13.A O no hydrogen 3.055 N/A LYS 16.A NZ GLU 112.A OE1 no hydrogen 3.229 N/A GLY 20.A N ASP 297.A OD2 no hydrogen 3.377 N/A LEU 21.A N GLY 17.A O no hydrogen 3.152 N/A ALA 22.A N TYR 18.A O no hydrogen 2.560 N/A GLU 23.A N ASN 19.A O no hydrogen 2.821 N/A GLU 23.A N GLY 20.A O no hydrogen 3.113 N/A VAL 24.A N GLY 20.A O no hydrogen 3.091 N/A GLY 25.A N LEU 21.A O no hydrogen 2.933 N/A LYS 26.A N ALA 22.A O no hydrogen 2.974 N/A LYS 27.A N GLU 23.A O no hydrogen 3.168 N/A LYS 27.A NZ GLU 289.A OE1 no hydrogen 3.170 N/A LYS 27.A NZ GLU 289.A OE2 no hydrogen 3.119 N/A PHE 28.A N VAL 24.A O no hydrogen 3.091 N/A GLU 29.A N GLY 25.A O no hydrogen 2.825 N/A LYS 30.A N LYS 26.A O no hydrogen 2.824 N/A ASP 31.A N LYS 27.A O no hydrogen 3.167 N/A THR 32.A N PHE 28.A O no hydrogen 2.803 N/A THR 32.A N GLU 29.A O no hydrogen 3.092 N/A THR 32.A OG1 PHE 28.A O no hydrogen 2.621 N/A GLY 33.A N GLU 29.A O no hydrogen 2.492 N/A ILE 34.A N THR 32.A OG1 no hydrogen 3.189 N/A LYS 35.A NZ THR 37.A OG1 no hydrogen 2.622 N/A THR 37.A N LEU 8.A O no hydrogen 2.876 N/A GLU 39.A N ILE 10.A O no hydrogen 2.804 N/A GLU 45.A N GLU 45.A OE1 no hydrogen 2.677 N/A GLU 46.A N LYS 43.A O no hydrogen 2.984 N/A LYS 47.A N LYS 43.A O no hydrogen 2.719 N/A PHE 48.A N LEU 44.A O no hydrogen 3.052 N/A VAL 51.A N LYS 47.A O no hydrogen 2.957 N/A ALA 52.A N PHE 48.A O no hydrogen 2.824 N/A ALA 53.A N PRO 49.A O no hydrogen 3.302 N/A THR 54.A N VAL 51.A O no hydrogen 2.986 N/A THR 54.A OG1 VAL 51.A O no hydrogen 2.713 N/A GLY 55.A N ALA 52.A O no hydrogen 2.829 N/A ASP 56.A N VAL 51.A O no hydrogen 3.178 N/A GLY 57.A N ASP 56.A OD1 no hydrogen 2.717 N/A ASP 59.A N VAL 9.A O no hydrogen 2.773 N/A ILE 60.A N VAL 9.A O no hydrogen 3.163 N/A ILE 61.A N GLY 266.A O no hydrogen 2.955 N/A PHE 62.A N TRP 11.A O no hydrogen 2.793 N/A TRP 63.A N SER 264.A O no hydrogen 3.034 N/A HIS 65.A NE2 MET 331.A O no hydrogen 2.599 N/A PHE 68.A N HIS 65.A O no hydrogen 3.066 N/A TYR 71.A N ARG 67.A O no hydrogen 3.246 N/A TYR 71.A OH GLU 45.A O no hydrogen 2.678 N/A ALA 72.A N PHE 68.A O no hydrogen 2.733 N/A GLN 73.A N GLY 69.A O no hydrogen 2.824 N/A SER 74.A N GLY 70.A O no hydrogen 2.845 N/A SER 74.A OG GLY 70.A O no hydrogen 3.003 N/A GLY 75.A N ALA 72.A O no hydrogen 2.894 N/A LEU 76.A N TYR 71.A O no hydrogen 2.921 N/A ALA 78.A N ILE 267.A O no hydrogen 2.839 N/A ILE 80.A N LEU 104.A O no hydrogen 2.880 N/A GLN 87.A N ALA 83.A O no hydrogen 2.808 N/A ASP 88.A N ALA 84.A O no hydrogen 2.950 N/A LYS 89.A N PHE 86.A O no hydrogen 2.899 N/A LEU 90.A N GLN 87.A O no hydrogen 2.978 N/A TYR 91.A N ALA 304.A O no hydrogen 2.906 N/A THR 94.A N TYR 91.A O no hydrogen 2.949 N/A THR 94.A OG1 TYR 91.A O no hydrogen 2.629 N/A TRP 95.A N TYR 91.A O no hydrogen 3.415 N/A TRP 95.A NE1 GLN 87.A O no hydrogen 2.739 N/A ASP 96.A N PRO 92.A O no hydrogen 2.934 N/A ALA 97.A N PHE 93.A O no hydrogen 3.228 N/A VAL 98.A N TRP 95.A O no hydrogen 3.065 N/A ARG 99.A N ASP 96.A O no hydrogen 3.341 N/A ARG 99.A NH1 ASP 96.A OD1 no hydrogen 2.729 N/A TYR 100.A N LYS 103.A O no hydrogen 2.806 N/A TYR 100.A OH GLN 73.A OE1 no hydrogen 2.650 N/A LYS 103.A N TYR 100.A O no hydrogen 3.199 N/A ILE 105.A N VAL 98.A O no hydrogen 2.864 N/A TYR 107.A N ALA 265.A O no hydrogen 2.842 N/A TYR 107.A OH GLU 282.A OE2 no hydrogen 2.377 N/A ILE 109.A N LEU 263.A O no hydrogen 2.555 N/A ALA 110.A N LEU 263.A O no hydrogen 3.424 N/A VAL 111.A N ALA 302.A O no hydrogen 2.908 N/A GLU 112.A N GLY 261.A O no hydrogen 2.674 N/A SER 115.A N ASN 228.A O no hydrogen 3.103 N/A LEU 116.A N THR 246.A O no hydrogen 3.052 N/A ILE 117.A N THR 226.A O no hydrogen 2.852 N/A TYR 118.A N GLY 244.A O no hydrogen 2.956 N/A ASN 119.A N ALA 224.A O no hydrogen 2.752 N/A LYS 120.A N ASN 242.A O no hydrogen 2.898 N/A LYS 120.A NZ ASN 242.A OD1 no hydrogen 2.959 N/A ASP 121.A N ASN 119.A OD1 no hydrogen 3.279 N/A LEU 123.A N ASN 119.A O no hydrogen 2.837 N/A THR 129.A OG1 THR 250.A OG1 no hydrogen 3.308 N/A TRP 130.A N THR 250.A O no hydrogen 2.746 N/A ILE 133.A N TRP 130.A O no hydrogen 3.188 N/A ASP 137.A N ILE 133.A O no hydrogen 2.715 N/A LYS 138.A N PRO 134.A O no hydrogen 3.412 N/A LEU 140.A N ASP 137.A O no hydrogen 2.454 N/A LYS 141.A N ASP 137.A O no hydrogen 2.603 N/A LYS 141.A NZ LYS 203.A O no hydrogen 2.856 N/A LYS 143.A N LEU 140.A O no hydrogen 2.836 N/A LYS 145.A N LEU 140.A O no hydrogen 2.351 N/A SER 146.A N GLU 222.A O no hydrogen 3.362 N/A ALA 147.A N ASP 137.A OD1 no hydrogen 3.022 N/A MET 149.A N MET 225.A O no hydrogen 3.115 N/A LEU 152.A N THR 209.A O no hydrogen 3.066 N/A GLN 153.A N ASN 151.A OD1 no hydrogen 2.628 N/A GLN 153.A NE2 ALA 207.A O no hydrogen 3.368 N/A GLN 153.A NE2 THR 209.A O no hydrogen 2.862 N/A PHE 157.A N GLU 154.A O no hydrogen 2.858 N/A THR 158.A N PRO 155.A O no hydrogen 3.186 N/A THR 158.A OG1 PRO 155.A O no hydrogen 3.372 N/A TRP 159.A N PRO 155.A O no hydrogen 2.720 N/A ILE 162.A N THR 158.A O no hydrogen 3.082 N/A ALA 163.A N TRP 159.A O no hydrogen 2.911 N/A ALA 163.A N PRO 160.A O no hydrogen 3.224 N/A ALA 164.A N LEU 161.A O no hydrogen 3.393 N/A GLY 166.A N ALA 163.A O no hydrogen 3.294 N/A TYR 168.A N GLY 183.A O no hydrogen 2.879 N/A TYR 168.A OH ASP 181.A OD1 no hydrogen 2.639 N/A LYS 171.A N ASP 181.A O no hydrogen 2.992 N/A GLU 173.A N LYS 176.A O no hydrogen 2.921 N/A LYS 176.A N GLU 173.A O no hydrogen 2.940 N/A ASP 178.A N LYS 171.A O no hydrogen 3.099 N/A LYS 180.A N ASP 178.A OD1 no hydrogen 3.019 N/A LYS 180.A NZ ASP 178.A OD1 no hydrogen 3.217 N/A LYS 180.A NZ GLU 382.A OE1.A no hydrogen 3.182 N/A ASP 181.A N ASP 178.A O no hydrogen 2.956 N/A GLY 183.A N ALA 169.A O no hydrogen 3.309 N/A VAL 184.A N GLN 366.A OE1 no hydrogen 2.857 N/A ASP 185.A N GLN 366.A OE1 no hydrogen 3.087 N/A ASN 186.A ND2 GLY 166.A O no hydrogen 2.697 N/A ALA 189.A N ASN 186.A OD1 no hydrogen 2.976 N/A LYS 190.A N ASN 186.A O no hydrogen 2.938 N/A LYS 190.A NZ ASP 359.A OD1 no hydrogen 2.852 N/A LYS 190.A NZ ASP 359.A OD2 no hydrogen 3.543 N/A ALA 191.A N ALA 187.A O no hydrogen 2.806 N/A GLY 192.A N GLY 188.A O no hydrogen 3.179 N/A LEU 193.A N ALA 189.A O no hydrogen 3.205 N/A THR 194.A N LYS 190.A O no hydrogen 2.778 N/A THR 194.A OG1 LYS 190.A O no hydrogen 2.983 N/A THR 194.A OG1 ALA 191.A O no hydrogen 2.685 N/A PHE 195.A N ALA 191.A O no hydrogen 3.046 N/A LEU 196.A N GLY 192.A O no hydrogen 3.245 N/A VAL 197.A N LEU 193.A O no hydrogen 2.944 N/A ASP 198.A N THR 194.A O no hydrogen 2.812 N/A LEU 199.A N LEU 196.A O no hydrogen 3.146 N/A ILE 200.A N VAL 197.A O no hydrogen 2.800 N/A LYS 201.A N VAL 197.A O no hydrogen 2.776 N/A HIS 204.A N LEU 199.A O no hydrogen 2.679 N/A MET 205.A N LEU 199.A O no hydrogen 2.847 N/A THR 209.A N ASN 206.A O no hydrogen 3.072 N/A THR 209.A OG1 ASN 206.A O no hydrogen 2.733 N/A TYR 211.A OH ASN 228.A OD1 no hydrogen 3.336 N/A ILE 213.A N ASP 210.A OD1 no hydrogen 2.865 N/A ALA 214.A N ASP 210.A O no hydrogen 2.976 N/A GLU 215.A N TYR 211.A O no hydrogen 3.024 N/A ALA 216.A N SER 212.A O no hydrogen 3.172 N/A ALA 217.A N ILE 213.A O no hydrogen 3.146 N/A PHE 218.A N ALA 214.A O no hydrogen 3.064 N/A ASN 219.A N GLU 215.A O no hydrogen 2.947 N/A LYS 220.A N ALA 216.A O no hydrogen 2.627 N/A GLY 221.A N PHE 218.A O no hydrogen 3.288 N/A GLU 222.A N ALA 217.A O no hydrogen 2.860 N/A THR 226.A N ILE 117.A O no hydrogen 2.873 N/A THR 226.A OG1 MET 149.A O no hydrogen 2.537 N/A ASN 228.A N SER 115.A O no hydrogen 3.345 N/A ASN 228.A ND2 TYR 211.A OH no hydrogen 3.260 N/A GLY 229.A N ASN 228.A OD1 no hydrogen 2.810 N/A TRP 231.A NE1 TYR 211.A OH no hydrogen 2.901 N/A ALA 232.A N GLY 229.A O no hydrogen 2.815 N/A TRP 233.A N PRO 230.A O no hydrogen 3.306 N/A SER 234.A OG ASP 297.A O no hydrogen 2.495 N/A ASN 235.A ND2 GLU 215.A OE2 no hydrogen 2.914 N/A ASP 237.A N TRP 233.A O no hydrogen 3.154 N/A THR 238.A N SER 234.A O no hydrogen 3.292 N/A THR 238.A OG1 ASN 235.A O no hydrogen 3.270 N/A SER 239.A OG ASN 219.A O no hydrogen 3.558 N/A SER 239.A OG ILE 236.A O no hydrogen 2.938 N/A ALA 240.A N ASP 237.A O no hydrogen 3.361 N/A VAL 241.A N SER 239.A OG no hydrogen 3.169 N/A TYR 243.A OH ASP 237.A OD1 no hydrogen 2.725 N/A GLY 244.A N TYR 118.A O no hydrogen 2.812 N/A THR 246.A N LEU 116.A O no hydrogen 2.727 N/A VAL 247.A N THR 246.A OG1 no hydrogen 2.781 N/A LEU 248.A N ASN 324.A OD1 no hydrogen 2.947 N/A THR 250.A N LYS 128.A O no hydrogen 3.078 N/A THR 250.A OG1 LYS 128.A O no hydrogen 3.369 N/A THR 250.A OG1 THR 129.A OG1 no hydrogen 3.308 N/A PHE 251.A N GLN 254.A O no hydrogen 2.847 N/A LYS 252.A N GLU 131.A OE2 no hydrogen 2.774 N/A GLN 254.A N PHE 251.A O no hydrogen 2.758 N/A VAL 260.A N GLU 329.A O no hydrogen 2.571 N/A GLY 261.A N GLU 112.A O no hydrogen 2.886 N/A VAL 262.A N HIS 65.A ND1 no hydrogen 2.916 N/A LEU 263.A N ALA 110.A O no hydrogen 2.870 N/A SER 264.A N TRP 63.A O no hydrogen 2.758 N/A SER 264.A OG VAL 262.A O no hydrogen 2.641 N/A ALA 265.A N TYR 107.A O no hydrogen 2.769 N/A GLY 266.A N ILE 61.A O no hydrogen 2.669 N/A ASN 268.A N ASP 59.A O no hydrogen 2.919 N/A ASN 268.A ND2 ASP 56.A O no hydrogen 2.858 N/A ASN 268.A ND2 PRO 58.A O no hydrogen 2.984 N/A ALA 269.A N LEU 76.A O no hydrogen 2.582 N/A ALA 270.A N ASN 268.A OD1 no hydrogen 2.828 N/A SER 271.A N ASN 268.A O no hydrogen 3.103 N/A SER 271.A OG ASP 59.A OD1 no hydrogen 2.634 N/A ASN 273.A N SER 271.A OG no hydrogen 2.684 N/A ASN 273.A ND2 GLU 4.A O no hydrogen 2.829 N/A ASN 273.A ND2 ASP 59.A OD1 no hydrogen 2.669 N/A LYS 274.A NZ ALA 269.A O no hydrogen 2.750 N/A LYS 274.A NZ SER 271.A O no hydrogen 2.892 N/A ALA 277.A N ASN 273.A O no hydrogen 2.808 N/A LYS 278.A N LYS 274.A O no hydrogen 2.961 N/A LYS 278.A NZ THR 81.A O no hydrogen 2.891 N/A LYS 278.A NZ GLU 282.A OE2 no hydrogen 3.111 N/A GLU 279.A N GLU 275.A O no hydrogen 2.937 N/A PHE 280.A N LEU 276.A O no hydrogen 2.828 N/A LEU 281.A N ALA 277.A O no hydrogen 2.923 N/A GLU 282.A N LYS 278.A O no hydrogen 2.832 N/A ASN 283.A N GLU 279.A O no hydrogen 3.052 N/A ASN 283.A ND2 GLU 279.A OE1 no hydrogen 3.208 N/A TYR 284.A N PHE 280.A O no hydrogen 3.164 N/A TYR 284.A OH ASP 31.A OD2 no hydrogen 3.006 N/A LEU 285.A N PHE 280.A O no hydrogen 3.050 N/A LEU 286.A N LEU 281.A O no hydrogen 2.837 N/A THR 287.A N LEU 285.A O no hydrogen 2.741 N/A THR 287.A OG1 TYR 284.A O no hydrogen 2.938 N/A GLY 290.A N THR 287.A OG1 no hydrogen 2.986 N/A LEU 291.A N THR 287.A O no hydrogen 2.914 N/A GLU 292.A N ASP 288.A O no hydrogen 3.030 N/A ALA 293.A N GLU 289.A O no hydrogen 3.149 N/A VAL 294.A N GLY 290.A O no hydrogen 3.081 N/A ASN 295.A N LEU 291.A O no hydrogen 2.568 N/A LYS 296.A N GLU 292.A O no hydrogen 2.720 N/A ASP 297.A N VAL 294.A O no hydrogen 2.930 N/A LYS 298.A N VAL 294.A O no hydrogen 3.124 N/A LYS 298.A NZ ASP 297.A O no hydrogen 3.186 N/A LYS 298.A NZ ASP 297.A OD1 no hydrogen 2.718 N/A LEU 300.A N ASN 295.A OD1 no hydrogen 2.736 N/A ALA 302.A N VAL 111.A O no hydrogen 3.159 N/A VAL 303.A N GLU 309.A OE1 no hydrogen 2.949 N/A ALA 304.A N ILE 109.A O no hydrogen 2.999 N/A LYS 306.A N LYS 89.A O no hydrogen 3.095 N/A LYS 306.A NZ ASP 88.A O no hydrogen 3.038 N/A SER 307.A OG ASP 288.A OD1 no hydrogen 2.410 N/A SER 307.A OG ASP 288.A OD2 no hydrogen 3.269 N/A GLU 309.A N LEU 305.A O no hydrogen 2.918 N/A GLU 310.A N LYS 306.A O no hydrogen 2.957 N/A LEU 312.A N TYR 308.A O no hydrogen 2.939 N/A ALA 313.A N GLU 309.A O no hydrogen 2.641 N/A LYS 314.A NZ GLU 310.A O no hydrogen 3.325 N/A ASP 315.A N LEU 312.A O no hydrogen 3.110 N/A ARG 317.A N ASP 315.A OD1 no hydrogen 2.748 N/A ARG 317.A NE ASP 315.A OD1 no hydrogen 3.168 N/A ARG 317.A NE ASP 315.A OD2 no hydrogen 3.137 N/A ARG 317.A NH1 TYR 243.A OH no hydrogen 3.009 N/A ARG 317.A NH2 ASP 315.A OD2 no hydrogen 2.570 N/A ALA 319.A N ASP 315.A O no hydrogen 3.209 N/A ALA 320.A N PRO 316.A O no hydrogen 2.859 N/A THR 321.A N ARG 317.A O no hydrogen 2.860 N/A THR 321.A OG1 ARG 317.A O no hydrogen 2.724 N/A MET 322.A N ILE 318.A O no hydrogen 2.901 N/A GLU 323.A N ALA 319.A O no hydrogen 2.935 N/A ASN 324.A N ALA 320.A O no hydrogen 2.879 N/A ASN 324.A ND2 THR 246.A O no hydrogen 3.385 N/A ASN 324.A ND2 ALA 320.A O no hydrogen 2.677 N/A ALA 325.A N THR 321.A O no hydrogen 2.880 N/A GLN 326.A N MET 322.A O no hydrogen 2.936 N/A LYS 327.A N ASN 324.A O no hydrogen 3.096 N/A GLY 328.A N ALA 325.A O no hydrogen 2.910 N/A GLU 329.A N PRO 258.A O no hydrogen 3.059 N/A MET 331.A N VAL 260.A O no hydrogen 2.892 N/A ASN 333.A ND2 ALA 97.A O no hydrogen 3.427 N/A ASN 333.A ND2 ARG 99.A O no hydrogen 2.908 N/A GLN 336.A N GLN 336.A OE1 no hydrogen 2.479 N/A GLN 336.A NE2 ARG 383.A OXT no hydrogen 3.501 N/A MET 337.A N ILE 334.A O no hydrogen 3.025 N/A PHE 340.A N GLN 336.A O no hydrogen 3.037 N/A TRP 341.A N MET 337.A O no hydrogen 2.902 N/A TYR 342.A N SER 338.A O no hydrogen 2.932 N/A ALA 343.A N ALA 339.A O no hydrogen 2.789 N/A VAL 344.A N PHE 340.A O no hydrogen 2.910 N/A ARG 345.A N TRP 341.A O no hydrogen 2.999 N/A THR 346.A N TYR 342.A O no hydrogen 2.997 N/A THR 346.A OG1 TYR 342.A O no hydrogen 3.317 N/A ALA 347.A N ALA 343.A O no hydrogen 3.014 N/A VAL 348.A N VAL 344.A O no hydrogen 2.980 N/A ILE 349.A N ARG 345.A O no hydrogen 3.062 N/A ASN 350.A N THR 346.A O no hydrogen 2.871 N/A ASN 350.A ND2 GLN 356.A OE1 no hydrogen 3.143 N/A ALA 351.A N VAL 348.A O no hydrogen 3.389 N/A ALA 352.A N VAL 348.A O no hydrogen 3.197 N/A SER 353.A N ILE 349.A O no hydrogen 3.209 N/A ARG 355.A N SER 353.A OG no hydrogen 3.271 N/A GLN 356.A N ASN 350.A O no hydrogen 3.164 N/A ALA 360.A N THR 357.A O no hydrogen 2.862 N/A ALA 360.A N THR 357.A OG1 no hydrogen 3.204 N/A ALA 361.A N THR 357.A O no hydrogen 2.680 N/A LEU 362.A N VAL 358.A O no hydrogen 3.042 N/A ALA 363.A N ASP 359.A O no hydrogen 3.134 N/A ALA 364.A N ALA 360.A O no hydrogen 3.231 N/A ALA 365.A N ALA 361.A O no hydrogen 3.372 N/A GLN 366.A N LEU 362.A O no hydrogen 3.024 N/A GLN 366.A NE2 VAL 182.A O no hydrogen 2.528 N/A THR 367.A N ALA 363.A O no hydrogen 3.217 N/A THR 367.A OG1 ALA 363.A O no hydrogen 2.734 N/A ASN 368.A N ALA 364.A O no hydrogen 2.856 N/A ALA 369.A N GLN 366.A O no hydrogen 3.125 N/A ALA 370.A N GLN 366.A O no hydrogen 3.044 N/A GLN 376.A N GLU 372.A O no hydrogen 3.218 N/A GLU 377.A N LEU 373.A O no hydrogen 3.057 N/A LEU 378.A N THR 374.A O no hydrogen 3.035 N/A LEU 379.A N LEU 375.A O no hydrogen 2.856 N/A GLY 380.A N GLN 376.A O no hydrogen 2.846 N/A GLU 381.A N GLN 376.A O no hydrogen 3.311 N/A