Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4xru_B.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): THR 5.A OG1 ASP 3.A OD1 no hydrogen 3.008 N/A THR 5.A OG1 ASP 3.A OD2 no hydrogen 2.896 N/A LEU 6.A N ASP 3.A O no hydrogen 2.878 N/A ILE 7.A N ASP 3.A O no hydrogen 2.717 N/A LYS 8.A N LYS 4.A O no hydrogen 2.771 N/A ARG 10.A N LEU 6.A O no hydrogen 3.094 N/A ARG 10.A NH1 GLU 384.A OE2 no hydrogen 2.908 N/A ARG 10.A NH2 GLU 384.A OE1 no hydrogen 3.392 N/A ARG 10.A NH2 GLU 384.A OE2 no hydrogen 2.889 N/A ILE 11.A N ILE 7.A O no hydrogen 2.893 N/A ASP 12.A N LYS 8.A O no hydrogen 3.130 N/A TRP 13.A N LYS 9.A O no hydrogen 3.006 N/A PHE 14.A N ARG 10.A O no hydrogen 2.962 N/A CYS 15.A N ILE 11.A O no hydrogen 2.861 N/A CYS 15.A N ASP 12.A O no hydrogen 2.925 N/A CYS 15.A SG ILE 11.A O no hydrogen 3.553 N/A LYS 16.A N ASP 12.A O no hydrogen 2.837 N/A ASN 17.A N TRP 13.A O no hydrogen 3.128 N/A LYS 18.A N CYS 15.A O no hydrogen 2.994 N/A LYS 18.A NZ TYR 363.A O no hydrogen 3.496 N/A LYS 18.A NZ LEU 366.A O no hydrogen 3.437 N/A ASN 20.A N TYR 70.A OH no hydrogen 2.947 N/A ASN 20.A ND2 ASN 20.A O no hydrogen 2.691 N/A ASN 20.A ND2 ILE 361.A O no hydrogen 3.134 N/A PHE 22.A N ASN 355.A OD1 no hydrogen 2.516 N/A SER 23.A OG PRO 24.A O no hydrogen 3.436 N/A THR 25.A OG1 ASP 351.A OD2 no hydrogen 3.322 N/A SER 27.A OG PRO 28.A O no hydrogen 3.094 N/A ALA 29.A N LYS 313.A O no hydrogen 2.976 N/A LYS 31.A NZ ARG 339.A O no hydrogen 3.062 N/A SER 32.A N GLU 37.A O no hydrogen 3.129 N/A SER 32.A OG GLU 34.A OE1 no hydrogen 3.468 N/A ARG 35.A N SER 32.A OG no hydrogen 3.038 N/A ASN 36.A N VAL 33.A O no hydrogen 2.943 N/A GLU 37.A N SER 32.A O no hydrogen 3.163 N/A SER 40.A N PRO 30.A O no hydrogen 3.102 N/A SER 40.A OG GLU 37.A OE2 no hydrogen 3.008 N/A TYR 42.A OH GLU 275.A OE1 no hydrogen 3.014 N/A TYR 42.A OH GLU 275.A OE2 no hydrogen 2.910 N/A GLU 43.A N SER 40.A OG no hydrogen 2.871 N/A GLY 44.A N SER 40.A O no hydrogen 2.948 N/A ILE 45.A N LEU 41.A O no hydrogen 3.140 N/A LEU 46.A N TYR 42.A O no hydrogen 2.831 N/A TRP 47.A N GLU 43.A O no hydrogen 2.734 N/A PHE 48.A N GLY 44.A O no hydrogen 3.285 N/A VAL 49.A N ILE 45.A O no hydrogen 2.896 N/A LEU 50.A N LEU 46.A O no hydrogen 3.035 N/A ASN 51.A N PHE 48.A O no hydrogen 3.201 N/A ASN 51.A ND2 TRP 47.A O no hydrogen 2.744 N/A GLY 52.A N VAL 49.A O no hydrogen 3.210 N/A ILE 56.A N GLN 267.A O no hydrogen 3.185 N/A VAL 57.A N LYS 299.A O no hydrogen 2.849 N/A ILE 58.A N HIS 265.A O no hydrogen 2.889 N/A GLU 59.A N VAL 297.A O no hydrogen 3.213 N/A LYS 61.A N GLY 295.A O no hydrogen 2.805 N/A LYS 61.A NZ GLU 294.A OE1 no hydrogen 2.576 N/A GLY 64.A N TYR 62.A O no hydrogen 3.116 N/A GLY 64.A N GLU 120.A OE2 no hydrogen 3.240 N/A SER 65.A N LEU 121.A O no hydrogen 3.109 N/A TYR 66.A OH ASP 68.A OD1 no hydrogen 2.420 N/A CYS 67.A N SER 119.A O no hydrogen 3.002 N/A ASP 68.A N VAL 81.A O no hydrogen 2.874 N/A ILE 69.A N ILE 117.A O no hydrogen 2.825 N/A TYR 70.A N TYR 79.A O no hydrogen 2.833 N/A HIS 72.A ND1 TYR 70.A O no hydrogen 3.236 N/A ARG 73.A N GLU 113.A O no hydrogen 3.171 N/A ARG 74.A NH2 GLU 76.A OE2 no hydrogen 2.650 N/A ASP 77.A N ARG 74.A O no hydrogen 2.780 N/A THR 78.A N LEU 75.A O no hydrogen 3.002 N/A THR 78.A OG1 LEU 75.A O no hydrogen 3.192 N/A TYR 79.A N TYR 70.A O no hydrogen 3.299 N/A TYR 79.A OH LYS 18.A O no hydrogen 2.664 N/A TYR 79.A OH TYR 363.A OH no hydrogen 2.615 N/A VAL 81.A N ASP 68.A O no hydrogen 2.892 N/A SER 82.A N TYR 86.A O no hydrogen 2.687 N/A SER 82.A OG ASN 84.A O no hydrogen 2.901 N/A SER 82.A OG TYR 86.A O no hydrogen 3.502 N/A TYR 86.A N SER 82.A OG no hydrogen 3.386 N/A LYS 87.A NZ ASN 17.A O no hydrogen 3.313 N/A ILE 88.A N LEU 80.A O no hydrogen 2.891 N/A GLU 94.A N ASP 92.A OD1 no hydrogen 3.091 N/A CYS 96.A N ASP 92.A O no hydrogen 3.068 N/A LEU 97.A N GLN 93.A O no hydrogen 3.193 N/A ARG 98.A N GLU 94.A O no hydrogen 2.785 N/A ALA 99.A N GLN 95.A O no hydrogen 3.382 N/A LEU 100.A N LEU 97.A O no hydrogen 2.983 N/A GLN 101.A N ARG 98.A O no hydrogen 3.284 N/A HIS 104.A N LEU 100.A O no hydrogen 3.066 N/A HIS 104.A NE2 ARG 73.A O no hydrogen 2.873 N/A ASP 105.A N GLN 101.A O no hydrogen 2.904 N/A ARG 106.A N LEU 103.A O no hydrogen 2.928 N/A ARG 106.A NE GLN 257.A O no hydrogen 3.158 N/A ARG 106.A NH2 ASP 261.A OD1 no hydrogen 2.384 N/A PHE 107.A N HIS 104.A O no hydrogen 3.322 N/A TRP 109.A NE1 HIS 104.A O no hydrogen 3.060 N/A GLU 113.A N VAL 240.A O no hydrogen 2.669 N/A LEU 114.A N VAL 240.A O no hydrogen 3.301 N/A ARG 115.A N LEU 71.A O no hydrogen 2.651 N/A ILE 116.A N LYS 238.A O no hydrogen 2.997 N/A ILE 117.A N ILE 69.A O no hydrogen 3.063 N/A GLN 118.A N ASN 235.A O no hydrogen 2.940 N/A GLN 118.A NE2 TYR 66.A OH no hydrogen 2.393 N/A SER 119.A N CYS 67.A O no hydrogen 2.992 N/A SER 119.A OG CYS 67.A O no hydrogen 3.098 N/A GLU 120.A N LYS 232.A O no hydrogen 2.697 N/A LEU 121.A N SER 65.A O no hydrogen 2.915 N/A MET 122.A N PHE 230.A O no hydrogen 2.762 N/A ILE 126.A N PRO 123.A O no hydrogen 3.181 N/A LEU 127.A N TRP 124.A O no hydrogen 3.357 N/A GLY 128.A N TRP 124.A O no hydrogen 2.960 N/A LYS 129.A N SER 125.A O no hydrogen 3.248 N/A LYS 129.A NZ GLU 226.A OE2 no hydrogen 3.238 N/A ILE 132.A N GLY 128.A O no hydrogen 2.807 N/A ASN 134.A N GLY 130.A O no hydrogen 2.636 N/A GLU 135.A N LEU 131.A O no hydrogen 3.155 N/A PHE 136.A N LEU 131.A O no hydrogen 3.446 N/A SER 137.A N ILE 132.A O no hydrogen 2.951 N/A SER 137.A OG ILE 132.A O no hydrogen 3.434 N/A TYR 139.A N GLU 135.A O no hydrogen 2.776 N/A TYR 140.A N PHE 136.A O no hydrogen 2.864 N/A ILE 141.A N SER 137.A O no hydrogen 2.904 N/A SER 142.A N ALA 138.A O no hydrogen 3.002 N/A SER 142.A OG ALA 138.A O no hydrogen 2.891 N/A HIS 143.A N TYR 139.A O no hydrogen 3.502 N/A HIS 143.A ND1 TYR 209.A OH no hydrogen 2.845 N/A GLU 144.A N TYR 140.A O no hydrogen 2.943 N/A ILE 145.A N ILE 141.A O no hydrogen 2.890 N/A HIS 146.A N SER 142.A O no hydrogen 3.102 N/A ALA 147.A N HIS 143.A O no hydrogen 2.684 N/A GLU 148.A N GLU 144.A O no hydrogen 2.824 N/A TYR 149.A N ILE 145.A O no hydrogen 2.924 N/A LEU 150.A N HIS 146.A O no hydrogen 3.034 N/A VAL 151.A N ALA 147.A O no hydrogen 2.973 N/A GLN 152.A N GLU 148.A O no hydrogen 2.931 N/A GLN 152.A NE2 GLU 148.A OE2 no hydrogen 2.949 N/A SER 153.A N TYR 149.A O no hydrogen 3.149 N/A LEU 155.A N SER 153.A OG no hydrogen 2.980 N/A LYS 158.A N SER 154.A O no hydrogen 3.097 N/A LYS 158.A NZ SER 154.A OG no hydrogen 3.096 N/A LEU 159.A N LEU 155.A O no hydrogen 3.128 N/A GLN 160.A N TYR 156.A O no hydrogen 3.223 N/A LYS 161.A N GLU 157.A O no hydrogen 3.236 N/A LYS 161.A NZ GLU 157.A OE1 no hydrogen 2.542 N/A ILE 162.A N LYS 158.A O no hydrogen 3.402 N/A GLN 163.A N LEU 159.A O no hydrogen 3.066 N/A GLN 164.A N LYS 161.A O no hydrogen 2.784 N/A GLN 164.A NE2 GLN 160.A O no hydrogen 3.204 N/A GLU 165.A N LYS 161.A O no hydrogen 3.415 N/A SER 170.A OG ALA 167.A O no hydrogen 2.367 N/A ALA 173.A N LEU 169.A O no hydrogen 2.601 N/A ASP 174.A N SER 170.A O no hydrogen 3.112 N/A VAL 177.A N ALA 173.A O no hydrogen 2.929 N/A LEU 183.A N ALA 180.A O no hydrogen 3.136 N/A LYS 186.A NZ ASP 174.A OD1 no hydrogen 3.340 N/A ARG 193.A N MET 189.A O no hydrogen 2.394 N/A TYR 195.A N ILE 191.A O no hydrogen 2.855 N/A GLN 196.A N ILE 192.A O no hydrogen 3.289 N/A SER 197.A N ARG 193.A O no hydrogen 2.787 N/A ILE 198.A N GLN 194.A O no hydrogen 3.045 N/A HIS 208.A N ASP 205.A O no hydrogen 2.671 N/A HIS 208.A NE2 ASP 330.A OD1 no hydrogen 3.104 N/A HIS 208.A NE2 ASP 330.A OD2 no hydrogen 3.247 N/A TYR 209.A N ASP 205.A O no hydrogen 2.876 N/A TYR 209.A OH HIS 143.A ND1 no hydrogen 2.845 N/A GLN 210.A N LEU 206.A O no hydrogen 3.095 N/A GLN 211.A N PRO 207.A O no hydrogen 2.952 N/A ASN 212.A N HIS 208.A O no hydrogen 2.764 N/A ILE 213.A N TYR 209.A O no hydrogen 3.322 N/A GLN 214.A N GLN 210.A O no hydrogen 2.756 N/A LEU 215.A N GLN 211.A O no hydrogen 2.942 N/A PHE 216.A N ASN 212.A O no hydrogen 3.140 N/A LYS 217.A N ILE 213.A O no hydrogen 2.788 N/A LYS 217.A NZ ASP 221.A OD1 no hydrogen 3.154 N/A ARG 218.A N GLN 214.A O no hydrogen 2.741 N/A GLN 219.A N LEU 215.A O no hydrogen 2.876 N/A LEU 220.A N PHE 216.A O no hydrogen 2.955 N/A ASP 221.A N LYS 217.A O no hydrogen 3.062 N/A ASP 221.A N ARG 218.A O no hydrogen 2.774 N/A ILE 222.A N ARG 218.A O no hydrogen 2.939 N/A PHE 223.A N GLN 219.A O no hydrogen 3.249 N/A GLY 224.A N LEU 220.A O no hydrogen 2.672 N/A PHE 230.A N MET 122.A O no hydrogen 3.050 N/A LYS 232.A N GLU 120.A O no hydrogen 3.014 N/A LYS 232.A NZ ASP 262.A OD1 no hydrogen 3.258 N/A LYS 232.A NZ ASP 262.A OD2 no hydrogen 3.529 N/A PHE 234.A N GLN 118.A O no hydrogen 2.800 N/A ASN 235.A N GLN 118.A O no hydrogen 3.347 N/A ASN 235.A ND2 GLN 118.A OE1 no hydrogen 3.200 N/A ILE 236.A N SER 254.A OG no hydrogen 2.673 N/A LEU 237.A N ILE 116.A O no hydrogen 2.749 N/A LYS 238.A NZ ASN 20.A OD1 no hydrogen 3.036 N/A LYS 238.A NZ GLU 246.A OE1 no hydrogen 2.525 N/A LYS 238.A NZ LEU 359.A O no hydrogen 2.864 N/A LYS 238.A NZ ILE 361.A O no hydrogen 2.952 N/A GLU 239.A N HIS 247.A O no hydrogen 3.125 N/A VAL 240.A N LEU 114.A O no hydrogen 2.854 N/A TYR 241.A N ARG 245.A O no hydrogen 2.887 N/A THR 242.A N GLY 111.A O no hydrogen 2.721 N/A THR 242.A OG1 GLY 111.A O no hydrogen 3.522 N/A GLY 244.A N TYR 241.A O no hydrogen 2.881 N/A HIS 247.A N GLU 239.A O no hydrogen 2.809 N/A VAL 249.A N LEU 237.A O no hydrogen 3.192 N/A ASN 252.A N ARG 301.A O no hydrogen 2.947 N/A ASN 252.A ND2 PRO 300.A O no hydrogen 3.594 N/A LEU 253.A N ASP 251.A OD1 no hydrogen 2.829 N/A SER 254.A N ASP 251.A O no hydrogen 2.833 N/A SER 254.A OG ASN 235.A OD1 no hydrogen 3.167 N/A ILE 258.A N SER 254.A O no hydrogen 3.161 N/A ASN 259.A N GLN 257.A O no hydrogen 3.080 N/A ASP 260.A N ASN 259.A OD1 no hydrogen 3.094 N/A TYR 266.A OH GLU 55.A OE1 no hydrogen 2.170 N/A GLN 267.A N ILE 56.A O no hydrogen 3.261 N/A GLN 267.A NE2 HIS 265.A NE2 no hydrogen 3.119 N/A THR 269.A OG1 THR 269.A O no hydrogen 2.662 N/A LYS 277.A N ASP 273.A O no hydrogen 2.567 N/A GLN 280.A N LYS 277.A O no hydrogen 2.967 N/A ARG 282.A N TYR 278.A O no hydrogen 2.822 N/A ARG 282.A NE TYR 278.A OH no hydrogen 3.513 N/A ARG 282.A NH1 ASP 286.A OD2 no hydrogen 3.275 N/A ALA 283.A N PRO 279.A O no hydrogen 3.112 N/A TRP 284.A N GLN 280.A O no hydrogen 2.894 N/A VAL 285.A N ILE 281.A O no hydrogen 3.018 N/A ASP 286.A N ARG 282.A O no hydrogen 2.961 N/A GLN 287.A N ALA 283.A O no hydrogen 3.285 N/A GLN 287.A N TRP 284.A O no hydrogen 3.036 N/A GLN 287.A NE2 ALA 283.A O no hydrogen 2.912 N/A VAL 288.A N TRP 284.A O no hydrogen 3.201 N/A ASN 289.A N VAL 285.A O no hydrogen 2.759 N/A GLN 290.A N ASP 286.A O no hydrogen 2.608 N/A SER 291.A N GLN 287.A O no hydrogen 2.428 N/A VAL 296.A N VAL 314.A O no hydrogen 3.101 N/A VAL 297.A N GLU 59.A O no hydrogen 3.149 N/A ILE 298.A N PHE 312.A O no hydrogen 2.825 N/A LYS 299.A N VAL 57.A O no hydrogen 2.968 N/A LYS 299.A NZ ASN 252.A OD1 no hydrogen 3.345 N/A ARG 301.A N GLU 55.A O no hydrogen 2.734 N/A PHE 304.A N ASN 250.A OD1 no hydrogen 2.697 N/A MET 308.A N LEU 305.A O no hydrogen 3.195 N/A PHE 312.A N ILE 298.A O no hydrogen 2.871 N/A LYS 313.A N SER 27.A O no hydrogen 2.838 N/A LYS 313.A NZ ILE 26.A O no hydrogen 3.263 N/A VAL 314.A N VAL 296.A O no hydrogen 2.813 N/A ARG 315.A N GLU 39.A OE1 no hydrogen 2.970 N/A ARG 315.A NE GLU 39.A OE2 no hydrogen 2.884 N/A ARG 315.A NH1 ARG 393.A O no hydrogen 3.470 N/A ARG 315.A NH2 GLU 39.A OE2 no hydrogen 2.570 N/A ARG 315.A NH2 ARG 393.A O no hydrogen 2.616 N/A ASN 316.A N GLU 294.A O no hydrogen 2.962 N/A ASN 316.A ND2 ASN 289.A OD1 no hydrogen 2.828 N/A ASN 316.A ND2 GLU 293.A O no hydrogen 2.809 N/A TYR 319.A N ASN 316.A OD1 no hydrogen 2.782 N/A LEU 320.A N ASN 316.A O no hydrogen 3.026 N/A THR 321.A N ASP 318.A O no hydrogen 2.874 N/A LEU 322.A N TYR 319.A O no hydrogen 2.753 N/A VAL 323.A N LEU 320.A O no hydrogen 2.934 N/A TYR 324.A N LEU 320.A O no hydrogen 3.070 N/A VAL 326.A N TYR 139.A OH no hydrogen 2.684 N/A ASP 330.A N ASP 327.A O no hydrogen 2.942 N/A ARG 331.A N ASP 327.A O no hydrogen 2.980 N/A ARG 331.A NH1 GLU 334.A OE2 no hydrogen 3.364 N/A GLN 335.A N ARG 331.A O no hydrogen 2.874 N/A ILE 336.A N LEU 332.A O no hydrogen 2.890 N/A ALA 337.A N GLN 333.A O no hydrogen 3.328 N/A LYS 338.A N GLU 334.A O no hydrogen 3.096 N/A LYS 338.A NZ GLU 334.A OE1 no hydrogen 3.039 N/A ARG 339.A N ILE 336.A O no hydrogen 3.110 N/A ARG 339.A NH2 GLU 39.A OE2 no hydrogen 2.934 N/A LYS 342.A N ASN 340.A OD1 no hydrogen 3.182 N/A LEU 345.A N ILE 341.A O no hydrogen 2.828 N/A CYS 347.A N GLY 343.A O no hydrogen 2.884 N/A CYS 347.A SG GLY 343.A O no hydrogen 3.011 N/A SER 348.A N LYS 344.A O no hydrogen 2.880 N/A SER 348.A OG THR 25.A O no hydrogen 2.850 N/A ILE 349.A N LEU 345.A O no hydrogen 3.017 N/A ASN 350.A N ARG 346.A O no hydrogen 3.252 N/A ASP 351.A N CYS 347.A O no hydrogen 2.716 N/A TRP 352.A N SER 348.A O no hydrogen 3.225 N/A TRP 352.A NE1 ALA 303.A O no hydrogen 2.734 N/A ALA 353.A N ILE 349.A O no hydrogen 2.934 N/A ILE 354.A N ASN 350.A O no hydrogen 2.802 N/A ILE 354.A N ASP 351.A O no hydrogen 3.064 N/A ASN 355.A N ASP 351.A O no hydrogen 2.799 N/A ALA 356.A N TRP 352.A O no hydrogen 3.074 N/A LEU 358.A N ILE 354.A O no hydrogen 2.772 N/A LEU 359.A N ASN 355.A O no hydrogen 2.895 N/A ALA 360.A N ALA 356.A O no hydrogen 3.117 N/A ILE 361.A N LEU 358.A O no hydrogen 2.954 N/A TYR 363.A N GLU 246.A OE2 no hydrogen 2.268 N/A TYR 363.A OH TYR 79.A OH no hydrogen 2.615 N/A GLU 365.A N PRO 362.A O no hydrogen 3.006 N/A LEU 366.A N TYR 363.A O no hydrogen 3.026 N/A ASN 370.A ND2 GLU 365.A O no hydrogen 3.372 N/A TYR 371.A OH GLU 369.A OE1 no hydrogen 3.254 N/A LEU 373.A N ASN 370.A OD1 no hydrogen 2.651 N/A LYS 374.A N ASN 370.A O no hydrogen 3.231 N/A LYS 374.A NZ ASP 12.A OD2 no hydrogen 3.187 N/A LYS 374.A NZ GLU 368.A O no hydrogen 3.201 N/A ASN 375.A N TYR 371.A O no hydrogen 3.163 N/A ASN 375.A ND2 TYR 371.A O no hydrogen 2.944 N/A LEU 376.A N GLU 372.A O no hydrogen 3.114 N/A VAL 377.A N LEU 373.A O no hydrogen 2.872 N/A LEU 378.A N LYS 374.A O no hydrogen 2.931 N/A ASP 379.A N ASN 375.A O no hydrogen 2.699 N/A ARG 380.A N LEU 376.A O no hydrogen 2.875 N/A ARG 380.A NE ARG 380.A O no hydrogen 3.133 N/A ARG 380.A NH2 GLU 387.A OE2 no hydrogen 2.208 N/A ILE 381.A N VAL 377.A O no hydrogen 2.625 N/A LEU 382.A N LEU 378.A O no hydrogen 2.981 N/A GLY 383.A N ASP 379.A O no hydrogen 3.060 N/A GLU 384.A N ARG 380.A O no hydrogen 2.791 N/A GLU 385.A N ILE 381.A O no hydrogen 2.923 N/A ILE 386.A N LEU 382.A O no hydrogen 3.163 N/A ILE 386.A N GLY 383.A O no hydrogen 3.264 N/A GLU 387.A N GLY 383.A O no hydrogen 2.913 N/A ASN 388.A N GLU 384.A O no hydrogen 3.043 N/A GLN 389.A N ILE 386.A O no hydrogen 3.003 N/A SER 392.A OG ASP 391.A O no hydrogen 2.745 N/A ARG 393.A NH2 GLN 335.A OE1 no hydrogen 3.560 N/A