Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4y7p_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 2.A NH1 GLU 28.A OE2 no hydrogen 3.157 N/A ASN 5.A N ASP 3.A OD1 no hydrogen 3.158 N/A SER 6.A OG ASP 3.A O no hydrogen 2.780 N/A LYS 8.A N ARG 4.A O no hydrogen 2.878 N/A GLN 9.A N ASN 5.A O no hydrogen 2.848 N/A GLN 9.A NE2 GLN 9.A O no hydrogen 3.591 N/A GLN 9.A NE2 ASP 13.A OD2 no hydrogen 3.158 N/A ALA 10.A N SER 6.A O no hydrogen 2.997 N/A VAL 11.A N VAL 7.A O no hydrogen 2.698 N/A ARG 12.A N LYS 8.A O no hydrogen 2.770 N/A ASP 13.A N GLN 9.A O no hydrogen 2.850 N/A THR 14.A N ALA 10.A O no hydrogen 3.171 N/A THR 14.A N VAL 11.A O no hydrogen 3.074 N/A THR 14.A OG1 ALA 10.A O no hydrogen 2.719 N/A LEU 15.A N ARG 12.A O no hydrogen 3.185 N/A GLN 16.A N ASP 13.A O no hydrogen 2.905 N/A LEU 17.A N THR 14.A O no hydrogen 2.903 N/A GLY 18.A N LEU 15.A O no hydrogen 2.881 N/A PHE 19.A N LEU 15.A O no hydrogen 3.156 N/A GLY 21.A N ASN 322.A OD1 no hydrogen 2.881 N/A ILE 22.A N ALA 37.A O no hydrogen 2.816 N/A LEU 23.A N ASN 320.A O no hydrogen 3.014 N/A ALA 24.A N TYR 35.A O no hydrogen 2.963 N/A LYS 25.A N ALA 318.A O no hydrogen 2.886 N/A LYS 25.A NZ ASP 51.A OD1 no hydrogen 2.450 N/A LYS 25.A NZ ASP 241.A OD1 no hydrogen 3.343 N/A LYS 25.A NZ ASP 241.A OD2 no hydrogen 3.036 N/A THR 26.A N TRP 33.A O no hydrogen 2.899 N/A SER 27.A N THR 316.A O no hydrogen 2.834 N/A GLU 28.A N LYS 31.A O no hydrogen 2.972 N/A GLY 29.A N LYS 314.A O no hydrogen 3.031 N/A LYS 31.A N GLU 28.A O no hydrogen 2.881 N/A TRP 33.A N THR 26.A O no hydrogen 3.057 N/A TYR 35.A N ALA 24.A O no hydrogen 2.834 N/A ALA 37.A N ILE 22.A O no hydrogen 2.984 N/A VAL 39.A N PRO 20.A O no hydrogen 2.759 N/A ALA 40.A N LYS 46.A O no hydrogen 2.734 N/A LEU 42.A N TYR 210.A OH no hydrogen 2.795 N/A SER 43.A N ASN 41.A OD1 no hydrogen 2.862 N/A SER 44.A N ASN 41.A OD1 no hydrogen 3.130 N/A LYS 45.A N ASN 41.A O no hydrogen 2.968 N/A LYS 46.A N SER 44.A OG no hydrogen 3.336 N/A MET 48.A N GLY 38.A O no hydrogen 2.872 N/A THR 50.A OG1 ASP 51.A OD1 no hydrogen 3.330 N/A ARG 53.A N LYS 205.A O no hydrogen 2.844 N/A ARG 53.A NE ASN 191.A OD1 no hydrogen 2.878 N/A ARG 53.A NH1 PRO 202.A O no hydrogen 2.902 N/A ARG 53.A NH2 ASN 191.A OD1 no hydrogen 2.822 N/A PHE 54.A N SER 238.A O no hydrogen 2.942 N/A ARG 55.A NH2 SER 199.A O no hydrogen 2.886 N/A ARG 55.A NH2 THR 223.A O no hydrogen 2.829 N/A ILE 56.A N MET 236.A O no hydrogen 2.892 N/A SER 58.A OG TYR 155.A OH no hydrogen 2.778 N/A VAL 59.A N ILE 56.A O no hydrogen 3.273 N/A THR 60.A N GLY 57.A O no hydrogen 2.923 N/A THR 60.A OG1 GLY 57.A O no hydrogen 2.742 N/A LYS 61.A N SER 58.A O no hydrogen 2.825 N/A LYS 61.A NZ SER 58.A OG no hydrogen 2.878 N/A LYS 61.A NZ TYR 155.A OH no hydrogen 2.843 N/A LYS 61.A NZ ASN 157.A OD1 no hydrogen 2.786 N/A LYS 61.A NZ ALA 233.A O no hydrogen 2.794 N/A THR 62.A N VAL 59.A O no hydrogen 3.018 N/A THR 62.A OG1 GLY 281.A O no hydrogen 2.536 N/A PHE 63.A N THR 60.A O no hydrogen 2.905 N/A THR 64.A N THR 60.A O no hydrogen 3.102 N/A THR 64.A OG1 THR 60.A O no hydrogen 3.498 N/A THR 64.A OG1 SER 232.A O no hydrogen 2.928 N/A ALA 65.A N LYS 61.A O no hydrogen 2.914 N/A THR 66.A N THR 62.A O no hydrogen 3.060 N/A THR 66.A OG1 THR 62.A O no hydrogen 2.673 N/A VAL 67.A N PHE 63.A O no hydrogen 3.113 N/A VAL 68.A N THR 64.A O no hydrogen 3.054 N/A LEU 69.A N ALA 65.A O no hydrogen 2.859 N/A GLN 70.A N THR 66.A O no hydrogen 2.983 N/A GLN 70.A NE2 LEU 255.A O no hydrogen 3.149 N/A LEU 71.A N VAL 67.A O no hydrogen 2.999 N/A ALA 72.A N VAL 68.A O no hydrogen 3.017 N/A GLU 73.A N LEU 69.A O no hydrogen 2.952 N/A GLU 74.A N GLN 70.A O no hydrogen 2.935 N/A ASN 75.A N ALA 72.A O no hydrogen 2.889 N/A ARG 76.A N LEU 71.A O no hydrogen 2.950 N/A ASN 78.A N ASP 81.A OD2 no hydrogen 3.005 N/A ASN 78.A ND2 ASP 81.A OD1 no hydrogen 3.005 N/A ASP 81.A N ASN 78.A O no hydrogen 2.874 N/A SER 82.A OG ASP 98.A O no hydrogen 2.799 N/A SER 82.A OG LYS 99.A O no hydrogen 3.345 N/A SER 82.A OG ILE 101.A O no hydrogen 3.519 N/A ILE 83.A N ILE 101.A O no hydrogen 2.829 N/A GLU 84.A N SER 82.A OG no hydrogen 3.013 N/A LYS 85.A N SER 82.A O no hydrogen 3.374 N/A LYS 85.A NZ ASP 81.A OD1 no hydrogen 2.854 N/A TRP 86.A N ILE 83.A O no hydrogen 2.891 N/A TRP 86.A NE1 ASP 81.A OD2 no hydrogen 2.997 N/A LEU 87.A N ILE 83.A O no hydrogen 2.727 N/A ASN 94.A ND2 ILE 141.A O no hydrogen 2.981 N/A ASN 94.A ND2 SER 142.A O no hydrogen 3.031 N/A TYR 96.A N GLY 93.A O no hydrogen 2.768 N/A TYR 96.A OH MET 143.A O no hydrogen 2.652 N/A LYS 99.A N ASP 97.A OD2 no hydrogen 3.277 N/A GLN 100.A N ASP 97.A O no hydrogen 3.090 N/A ILE 101.A N ASP 98.A O no hydrogen 3.207 N/A THR 102.A N GLN 105.A OE1 no hydrogen 3.057 N/A ILE 103.A N ASP 81.A O no hydrogen 3.176 N/A ARG 104.A N LEU 79.A O no hydrogen 2.804 N/A ARG 104.A NE ASP 80.A OD1 no hydrogen 2.970 N/A ARG 104.A NH1 GLN 263.A OE1 no hydrogen 2.744 N/A ARG 104.A NH2 ASP 80.A OD2 no hydrogen 3.205 N/A ARG 104.A NH2 GLN 263.A OE1 no hydrogen 3.378 N/A GLN 105.A N THR 102.A OG1 no hydrogen 3.281 N/A LEU 106.A N THR 102.A O no hydrogen 3.213 N/A LEU 107.A N ILE 103.A O no hydrogen 3.113 N/A ASN 108.A N ARG 104.A O no hydrogen 3.099 N/A ASN 108.A ND2 THR 110.A OG1 no hydrogen 2.690 N/A HIS 109.A N LEU 106.A O no hydrogen 3.474 N/A HIS 109.A NE2 TYR 278.A OH no hydrogen 3.002 N/A THR 110.A N GLN 105.A O no hydrogen 2.830 N/A ILE 113.A N SER 111.A OG no hydrogen 2.875 N/A ALA 114.A N TYR 96.A OH no hydrogen 3.186 N/A TYR 116.A N THR 158.A OG1 no hydrogen 2.878 N/A TYR 116.A OH MET 229.A O no hydrogen 2.781 N/A THR 117.A N GLU 115.A OE1 no hydrogen 3.036 N/A THR 117.A OG1 GLU 115.A OE1 no hydrogen 2.500 N/A ARG 118.A N GLU 115.A O no hydrogen 3.055 N/A SER 119.A N TYR 116.A O no hydrogen 2.990 N/A SER 119.A OG SER 121.A OG no hydrogen 2.689 N/A SER 121.A N SER 119.A OG no hydrogen 2.964 N/A SER 121.A OG SER 119.A OG no hydrogen 2.689 N/A PHE 122.A N SER 119.A O no hydrogen 3.068 N/A MET 125.A N ASP 123.A OD1 no hydrogen 2.967 N/A ASP 126.A N ASP 123.A O no hydrogen 2.882 N/A LYS 128.A N ASP 126.A OD1 no hydrogen 3.017 N/A LYS 129.A N ASP 126.A OD1 no hydrogen 3.127 N/A SER 130.A OG ASN 226.A OD1 no hydrogen 2.985 N/A TYR 131.A N SER 228.A OG no hydrogen 2.847 N/A ARG 132.A N GLU 135.A OE1 no hydrogen 2.801 N/A GLU 135.A N ARG 132.A O no hydrogen 2.906 N/A LEU 136.A N ARG 132.A O no hydrogen 3.462 N/A VAL 137.A N ALA 133.A O no hydrogen 3.082 N/A LYS 138.A N GLU 134.A O no hydrogen 2.958 N/A LYS 138.A NZ GLU 134.A OE2 no hydrogen 2.946 N/A MET 139.A N GLU 135.A O no hydrogen 3.040 N/A GLY 140.A N LEU 136.A O no hydrogen 2.961 N/A ILE 141.A N VAL 137.A O no hydrogen 3.020 N/A SER 142.A N LYS 138.A O no hydrogen 3.047 N/A SER 142.A OG MET 139.A O no hydrogen 2.701 N/A MET 143.A N GLY 140.A O no hydrogen 3.183 N/A ASP 146.A N GLY 112.A O no hydrogen 3.003 N/A GLY 150.A N THR 110.A O no hydrogen 2.807 N/A LYS 151.A N ALA 148.A O no hydrogen 2.918 N/A SER 154.A N HIS 109.A O no hydrogen 3.067 N/A TYR 155.A OH SER 58.A OG no hydrogen 2.778 N/A SER 156.A N HIS 109.A ND1 no hydrogen 3.013 N/A SER 156.A OG ILE 113.A O no hydrogen 2.832 N/A ASN 157.A N GLU 115.A OE2 no hydrogen 2.639 N/A ASN 157.A ND2 GLU 115.A OE1 no hydrogen 2.984 N/A THR 158.A OG1 ALA 114.A O no hydrogen 2.607 N/A GLY 159.A N SER 156.A O no hydrogen 3.298 N/A TYR 160.A OH LEU 107.A O no hydrogen 2.539 N/A VAL 161.A N ASN 157.A O no hydrogen 2.911 N/A LEU 162.A N THR 158.A O no hydrogen 2.917 N/A LEU 163.A N GLY 159.A O no hydrogen 2.994 N/A GLY 164.A N TYR 160.A O no hydrogen 3.125 N/A ILE 165.A N VAL 161.A O no hydrogen 3.189 N/A LEU 166.A N LEU 162.A O no hydrogen 2.928 N/A ILE 167.A N LEU 163.A O no hydrogen 2.913 N/A THR 169.A N ILE 165.A O no hydrogen 2.926 N/A THR 169.A OG1 ILE 165.A O no hydrogen 3.077 N/A VAL 170.A N LEU 166.A O no hydrogen 2.871 N/A VAL 170.A N ILE 167.A O no hydrogen 3.195 N/A THR 171.A N ILE 167.A O no hydrogen 2.941 N/A THR 171.A OG1 ILE 167.A O no hydrogen 3.050 N/A THR 171.A OG1 GLU 178.A OE2 no hydrogen 2.890 N/A GLY 172.A N GLU 168.A O no hydrogen 2.704 N/A ASN 173.A N THR 171.A OG1 no hydrogen 2.888 N/A ASN 173.A ND2 GLU 178.A OE2 no hydrogen 2.853 N/A TYR 175.A OH ASP 235.A OD2 no hydrogen 2.504 N/A GLU 177.A N SER 174.A OG no hydrogen 2.971 N/A GLU 178.A N SER 174.A O no hydrogen 3.037 N/A ILE 179.A N TYR 175.A O no hydrogen 2.826 N/A GLU 180.A N ALA 176.A O no hydrogen 2.806 N/A ASN 181.A N GLU 177.A O no hydrogen 2.800 N/A ARG 182.A N GLU 178.A O no hydrogen 2.934 N/A ARG 182.A NE GLU 178.A OE1 no hydrogen 2.843 N/A ARG 182.A NH1 GLN 70.A OE1 no hydrogen 2.971 N/A ARG 182.A NH1 GLU 74.A OE1 no hydrogen 3.463 N/A ARG 182.A NH1 GLU 74.A OE2 no hydrogen 2.740 N/A ARG 182.A NH2 GLU 74.A OE1 no hydrogen 2.881 N/A ILE 183.A N ILE 179.A O no hydrogen 3.015 N/A ILE 184.A N ILE 179.A O no hydrogen 3.146 N/A GLU 185.A N GLU 180.A O no hydrogen 2.957 N/A LEU 187.A N ILE 183.A O no hydrogen 2.952 N/A GLU 188.A N GLU 185.A O no hydrogen 3.060 N/A LEU 189.A N ILE 184.A O no hydrogen 2.872 N/A ASN 191.A N ASP 242.A OD2 no hydrogen 2.883 N/A THR 192.A N LEU 189.A O no hydrogen 3.115 N/A THR 192.A OG1 SER 238.A OG no hydrogen 2.626 N/A THR 192.A OG1 ASP 242.A OD2 no hydrogen 2.682 N/A PHE 193.A N ILE 237.A O no hydrogen 2.811 N/A SER 198.A N PRO 195.A O no hydrogen 2.948 N/A VAL 200.A N SER 198.A OG no hydrogen 3.332 N/A LYS 205.A NZ ASN 191.A OD1 no hydrogen 2.950 N/A HIS 206.A N THR 204.A O no hydrogen 2.872 N/A HIS 206.A ND1 ALA 207.A O no hydrogen 2.757 N/A ARG 208.A N ALA 40.A O no hydrogen 2.967 N/A ARG 208.A NH1 ASP 221.A OD1 no hydrogen 3.277 N/A ARG 208.A NH1 ASP 221.A OD2 no hydrogen 3.067 N/A GLY 209.A N THR 223.A OG1 no hydrogen 2.996 N/A TYR 210.A N GLY 302.A O no hydrogen 3.383 N/A TYR 210.A N ASN 322.A O no hydrogen 3.054 N/A ILE 211.A N LYS 220.A O no hydrogen 2.946 N/A GLN 212.A N LEU 324.A O no hydrogen 2.864 N/A LYS 220.A N ILE 211.A O no hydrogen 2.837 N/A VAL 222.A N GLY 209.A O no hydrogen 2.653 N/A THR 223.A N ASP 221.A OD1 no hydrogen 2.939 N/A THR 223.A OG1 ASP 221.A OD1 no hydrogen 2.567 N/A THR 223.A OG1 ASP 221.A OD2 no hydrogen 3.464 N/A TYR 225.A OH LEU 124.A O no hydrogen 2.582 N/A GLY 230.A N PRO 227.A O no hydrogen 2.885 N/A SER 231.A N PRO 227.A O no hydrogen 3.187 N/A SER 232.A OG TYR 160.A O no hydrogen 2.553 N/A ALA 233.A N GLY 230.A O no hydrogen 2.867 N/A GLY 234.A N SER 231.A O no hydrogen 2.971 N/A ASP 235.A N SER 231.A O no hydrogen 2.884 N/A MET 236.A N THR 60.A OG1 no hydrogen 2.961 N/A ILE 237.A N PHE 193.A O no hydrogen 3.043 N/A SER 238.A N PHE 54.A O no hydrogen 2.967 N/A SER 238.A OG THR 192.A OG1 no hydrogen 2.626 N/A ASP 242.A N THR 239.A OG1 no hydrogen 3.095 N/A LEU 243.A N THR 239.A O no hydrogen 2.993 N/A ASN 244.A N ALA 240.A O no hydrogen 2.980 N/A ASN 244.A ND2 LYS 25.A O no hydrogen 3.128 N/A LYS 245.A N ASP 241.A O no hydrogen 3.078 N/A LYS 245.A NZ LEU 187.A O no hydrogen 2.788 N/A PHE 246.A N ASP 242.A O no hydrogen 2.935 N/A PHE 247.A N LEU 243.A O no hydrogen 2.964 N/A SER 248.A N ASN 244.A O no hydrogen 2.897 N/A SER 248.A OG GLY 313.A O no hydrogen 3.061 N/A TYR 249.A N LYS 245.A O no hydrogen 2.886 N/A LEU 250.A N PHE 246.A O no hydrogen 2.908 N/A LEU 251.A N PHE 247.A O no hydrogen 2.900 N/A GLY 252.A N SER 248.A O no hydrogen 2.992 N/A GLY 253.A N LEU 250.A O no hydrogen 3.312 N/A LYS 254.A N TYR 249.A O no hydrogen 2.808 N/A LYS 257.A NZ GLU 73.A OE2 no hydrogen 3.538 N/A LEU 261.A N LYS 257.A O no hydrogen 2.855 N/A LYS 262.A N GLU 258.A O no hydrogen 2.897 N/A GLN 263.A N GLN 259.A O no hydrogen 3.258 N/A MET 264.A N GLN 260.A O no hydrogen 2.978 N/A LEU 265.A N LEU 261.A O no hydrogen 2.821 N/A THR 266.A N GLN 263.A O no hydrogen 3.056 N/A THR 266.A OG1 LYS 262.A O no hydrogen 2.769 N/A VAL 268.A N TYR 278.A O no hydrogen 2.956 N/A THR 270.A OG1 LEU 275.A O.A no hydrogen 3.511 N/A THR 270.A OG1 GLY 276.A O.A no hydrogen 3.379 N/A THR 270.A OG1 GLY 276.A O.B no hydrogen 2.246 N/A GLY 271.A N ALA 274.A O.B no hydrogen 3.182 N/A ALA 274.A N.A GLU 272.A OE1.B no hydrogen 3.456 N/A ARG 277.A NE THR 267.A OG1 no hydrogen 2.873 N/A ARG 277.A NH2 THR 267.A O no hydrogen 3.288 N/A TYR 278.A N VAL 268.A O no hydrogen 2.996 N/A TYR 278.A OH HIS 296.A NE2 no hydrogen 2.641 N/A GLY 279.A N ILE 282.A O no hydrogen 2.731 N/A LEU 280.A N MET 264.A O no hydrogen 2.968 N/A GLY 281.A N LEU 107.A O no hydrogen 3.182 N/A TYR 283.A N GLY 295.A O no hydrogen 2.934 N/A GLU 284.A N ARG 277.A O no hydrogen 2.885 N/A THR 285.A N ILE 293.A O no hydrogen 2.810 N/A LEU 287.A N VAL 291.A O no hydrogen 2.703 N/A ASN 289.A ND2 PHE 340.A O no hydrogen 3.424 N/A GLY 290.A N LEU 287.A O no hydrogen 2.920 N/A VAL 291.A N ASN 289.A OD1 no hydrogen 3.061 N/A SER 292.A OG GLU 284.A OE2 no hydrogen 2.545 N/A ILE 293.A N THR 285.A O no hydrogen 2.672 N/A TRP 294.A N GLY 309.A O no hydrogen 2.555 N/A GLY 295.A N TYR 283.A O no hydrogen 3.059 N/A HIS 296.A N ALA 307.A O no hydrogen 2.913 N/A HIS 296.A ND1 GLY 297.A O no hydrogen 2.731 N/A HIS 296.A NE2 TYR 278.A OH no hydrogen 2.641 N/A GLY 297.A N TYR 283.A OH no hydrogen 2.975 N/A GLY 298.A N THR 305.A O no hydrogen 2.942 N/A ILE 300.A N PHE 303.A O no hydrogen 2.961 N/A PHE 303.A N ILE 300.A O no hydrogen 2.835 N/A VAL 304.A N LEU 321.A O no hydrogen 3.003 N/A THR 305.A N GLY 298.A O no hydrogen 2.892 N/A THR 305.A OG1 ARG 55.A O no hydrogen 3.411 N/A PHE 306.A N VAL 319.A O no hydrogen 2.992 N/A ALA 307.A N HIS 296.A O no hydrogen 3.186 N/A GLY 308.A N LEU 317.A O no hydrogen 3.026 N/A GLY 309.A N TRP 294.A O no hydrogen 2.709 N/A THR 310.A N HIS 315.A O no hydrogen 3.104 N/A GLY 312.A N LEU 251.A O no hydrogen 3.101 N/A GLY 313.A N THR 310.A O no hydrogen 2.802 N/A HIS 315.A NE2 GLU 339.A OE2 no hydrogen 2.662 N/A THR 316.A N SER 27.A O no hydrogen 2.787 N/A THR 316.A OG1 ASN 244.A OD1 no hydrogen 2.916 N/A LEU 317.A N GLY 308.A O no hydrogen 3.032 N/A ALA 318.A N LYS 25.A O no hydrogen 2.900 N/A VAL 319.A N PHE 306.A O no hydrogen 2.846 N/A ASN 320.A N LEU 23.A O no hydrogen 3.007 N/A ASN 320.A ND2 THR 305.A OG1 no hydrogen 3.011 N/A LEU 321.A N VAL 304.A O no hydrogen 2.721 N/A ASN 322.A N GLY 21.A O no hydrogen 3.403 N/A ASN 322.A ND2 VAL 39.A O no hydrogen 3.345 N/A ASN 322.A ND2 ARG 208.A O no hydrogen 3.002 N/A LEU 324.A N TYR 210.A O no hydrogen 2.831 N/A ASN 325.A ND2 GLY 18.A O no hydrogen 2.882 N/A ALA 326.A N GLN 212.A O no hydrogen 3.313 N/A GLU 327.A N ASN 325.A OD1 no hydrogen 3.110 N/A SER 328.A N ASN 325.A O no hydrogen 2.943 N/A SER 328.A OG LEU 17.A O no hydrogen 3.113 N/A LEU 336.A N PHE 332.A O no hydrogen 3.165 N/A LEU 337.A N LYS 333.A O no hydrogen 3.071 N/A ALA 338.A N ASN 334.A O no hydrogen 2.986 N/A GLU 339.A N ILE 335.A O no hydrogen 2.856 N/A PHE 340.A N LEU 336.A O no hydrogen 2.808 N/A SER 341.A N LEU 337.A O no hydrogen 2.967 N/A SER 341.A OG LEU 337.A O no hydrogen 2.846 N/A LYS 342.A NZ LYS 342.A O no hydrogen 3.136 N/A