Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4ye4_G.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 1.A N LYS 333.A O no hydrogen 2.700 N/A ALA 3.A N VAL 331.A O no hydrogen 3.112 N/A LEU 7.A N GLN 56.A OE1 no hydrogen 2.838 N/A PHE 8.A N CYS 98.A O no hydrogen 3.012 N/A CYS 9.A SG ALA 28.A O no hydrogen 3.322 N/A ALA 10.A N HIS 96.A O no hydrogen 2.911 N/A SER 11.A N VAL 30.A O no hydrogen 2.757 N/A ALA 13.A N SER 11.A OG no hydrogen 3.187 N/A LYS 14.A N ASN 22.A OD1 no hydrogen 3.054 N/A GLU 17.A N LYS 14.A O no hydrogen 3.248 N/A GLU 19.A N GLU 17.A OE2 no hydrogen 3.260 N/A VAL 20.A N SER 89.A O no hydrogen 3.120 N/A HIS 21.A N GLU 19.A OE2 no hydrogen 3.087 N/A HIS 21.A ND1 GLU 19.A OE2 no hydrogen 2.550 N/A ASN 22.A N GLU 19.A OE1 no hydrogen 2.695 N/A ASN 22.A ND2 GLU 19.A OE1 no hydrogen 2.975 N/A VAL 23.A N GLU 19.A O no hydrogen 2.947 N/A TRP 24.A N VAL 20.A O no hydrogen 2.955 N/A ALA 25.A N HIS 21.A O no hydrogen 2.866 N/A THR 26.A N ASN 22.A O no hydrogen 2.896 N/A THR 26.A OG1 ASN 22.A O no hydrogen 2.391 N/A HIS 27.A N TRP 24.A O no hydrogen 3.127 N/A ALA 28.A N TRP 24.A O no hydrogen 2.903 N/A CYS 29.A N ALA 25.A O no hydrogen 2.871 N/A VAL 30.A N CYS 9.A O no hydrogen 2.952 N/A THR 32.A N SER 11.A O no hydrogen 3.065 N/A VAL 37.A N THR 124.A O no hydrogen 2.968 N/A LEU 39.A N VAL 122.A O no hydrogen 3.106 N/A GLU 44.A N CYS 119.A O no hydrogen 3.028 N/A PHE 46.A N GLY 117.A O no hydrogen 2.890 N/A MET 48.A N GLY 115.A O no hydrogen 2.974 N/A TRP 49.A N ASN 47.A OD1 no hydrogen 3.084 N/A LYS 50.A N ASN 47.A O no hydrogen 3.046 N/A MET 53.A N ASN 51.A OD1 no hydrogen 3.135 N/A VAL 54.A N ASN 51.A O no hydrogen 2.934 N/A GLN 56.A N ASN 52.A O no hydrogen 2.956 N/A GLN 56.A NE2 THR 5.A O no hydrogen 2.161 N/A GLN 56.A NE2 ASN 52.A OD1 no hydrogen 2.981 N/A MET 57.A N MET 53.A O no hydrogen 2.936 N/A GLN 58.A N VAL 54.A O no hydrogen 2.952 N/A GLU 59.A N GLU 55.A O no hydrogen 2.935 N/A ASP 60.A N GLN 56.A O no hydrogen 2.978 N/A ILE 61.A N MET 57.A O no hydrogen 2.899 N/A ILE 62.A N GLN 58.A O no hydrogen 2.896 N/A SER 63.A N GLU 59.A O no hydrogen 2.963 N/A SER 63.A OG GLU 59.A O no hydrogen 3.322 N/A SER 63.A OG ASP 60.A O no hydrogen 2.490 N/A LEU 64.A N ASP 60.A O no hydrogen 2.866 N/A TRP 65.A N ILE 61.A O no hydrogen 2.926 N/A ASP 66.A N ILE 62.A O no hydrogen 2.868 N/A GLN 67.A N SER 63.A O no hydrogen 2.936 N/A SER 68.A N TRP 65.A O no hydrogen 2.980 N/A SER 68.A OG LEU 64.A O no hydrogen 2.637 N/A LEU 69.A N TRP 65.A O no hydrogen 2.652 N/A LYS 70.A NZ GLN 67.A O no hydrogen 2.824 N/A CYS 72.A N MET 275.A O no hydrogen 2.415 N/A VAL 73.A N MET 275.A O no hydrogen 3.045 N/A LYS 74.A N ILE 81.A O no hydrogen 2.840 N/A LEU 75.A N LYS 273.A O no hydrogen 2.869 N/A THR 76.A N SER 79.A O no hydrogen 2.901 N/A SER 79.A N THR 76.A O no hydrogen 2.913 N/A SER 79.A OG GLY 77.A O no hydrogen 3.561 N/A ILE 81.A N LYS 74.A O no hydrogen 2.878 N/A GLN 83.A N CYS 72.A O no hydrogen 3.033 N/A GLN 83.A NE2 PRO 71.A O no hydrogen 3.218 N/A LYS 87.A NZ PRO 278.A O no hydrogen 2.373 N/A GLU 91.A N GLU 19.A OE2 no hydrogen 2.822 N/A ILE 95.A N ILE 131.A O no hydrogen 2.699 N/A HIS 96.A N ALA 10.A O no hydrogen 2.851 N/A HIS 96.A ND1 THR 128.A O no hydrogen 3.043 N/A TYR 97.A N THR 128.A OG1 no hydrogen 2.927 N/A TYR 97.A OH ASP 60.A OD2 no hydrogen 2.636 N/A CYS 98.A N PHE 8.A O no hydrogen 2.847 N/A THR 99.A OG1 PHE 103.A O no hydrogen 3.333 N/A PHE 103.A N PRO 100.A O no hydrogen 3.246 N/A ALA 104.A N VAL 332.A O no hydrogen 2.892 N/A LEU 106.A N LYS 330.A O no hydrogen 2.885 N/A LYS 107.A N SER 123.A O no hydrogen 2.829 N/A CYS 108.A N LYS 328.A O no hydrogen 2.772 N/A ASN 109.A N ASN 121.A O no hydrogen 2.905 N/A THR 116.A N ASN 114.A OD1 no hydrogen 3.024 N/A GLY 117.A N PHE 46.A O no hydrogen 2.927 N/A CYS 119.A N GLU 44.A O no hydrogen 2.902 N/A CYS 119.A SG ASN 121.A O no hydrogen 3.699 N/A LYS 120.A N ASP 110.A OD2 no hydrogen 2.983 N/A ASN 121.A N ASP 110.A OD1 no hydrogen 2.881 N/A SER 123.A N LYS 107.A O no hydrogen 2.960 N/A SER 123.A OG GLU 36.A OE1 no hydrogen 3.349 N/A SER 123.A OG ASN 109.A OD1 no hydrogen 3.530 N/A THR 124.A N VAL 37.A O no hydrogen 2.691 N/A THR 124.A OG1 ILE 105.A O no hydrogen 3.406 N/A VAL 125.A N ILE 105.A O no hydrogen 2.881 N/A THR 128.A N TYR 97.A O no hydrogen 2.865 N/A THR 128.A OG1 HIS 129.A O no hydrogen 3.002 N/A HIS 129.A N TYR 329.A OH no hydrogen 2.887 N/A HIS 129.A ND1 TYR 329.A OH no hydrogen 2.519 N/A HIS 129.A NE2 GLU 325.A OE1 no hydrogen 3.044 N/A ILE 131.A N ILE 95.A O no hydrogen 2.769 N/A VAL 134.A N LYS 132.A O no hydrogen 2.768 N/A SER 136.A OG LEU 139.A O no hydrogen 2.590 N/A THR 137.A N SER 229.A O no hydrogen 2.867 N/A THR 137.A OG1 GLU 224.A O no hydrogen 2.671 N/A THR 137.A OG1 MET 227.A O no hydrogen 3.080 N/A THR 137.A OG1 SER 229.A OG no hydrogen 2.979 N/A GLN 138.A N GLY 314.A O no hydrogen 3.134 N/A GLN 138.A NE2 ILE 225.A O no hydrogen 2.809 N/A LEU 139.A N THR 137.A O no hydrogen 2.584 N/A LEU 140.A N GLY 292.A O no hydrogen 2.765 N/A ASN 142.A N ASN 289.A O no hydrogen 2.658 N/A GLY 143.A N THR 291.A OG1 no hydrogen 2.862 N/A SER 144.A N GLU 325.A OE2 no hydrogen 3.028 N/A SER 144.A OG GLU 325.A OE1 no hydrogen 3.230 N/A ALA 146.A N LEU 168.A O no hydrogen 2.978 N/A GLU 149.A N ASN 112.A OD1 no hydrogen 2.776 N/A VAL 151.A N GLN 167.A O no hydrogen 3.016 N/A ARG 153.A N ILE 165.A O no hydrogen 2.880 N/A ASN 156.A N SER 154.A OG no hydrogen 3.091 N/A THR 158.A N ASN 156.A OD1 no hydrogen 2.935 N/A ASN 159.A N ASN 156.A O no hydrogen 2.962 N/A ASN 160.A ND2 ARG 297.A O no hydrogen 3.436 N/A ALA 161.A N ASN 159.A OD1 no hydrogen 2.941 N/A LYS 162.A N ASN 159.A O no hydrogen 2.996 N/A LYS 162.A NZ GLU 155.A OE1 no hydrogen 3.267 N/A ILE 164.A N LEU 295.A O no hydrogen 2.857 N/A ILE 165.A N ARG 153.A O no hydrogen 2.828 N/A ILE 166.A N LEU 293.A O no hydrogen 2.877 N/A GLN 167.A N VAL 151.A O no hydrogen 2.844 N/A GLN 167.A NE2 SER 144.A O no hydrogen 3.659 N/A GLN 167.A NE2 TYR 327.A OH no hydrogen 3.255 N/A LEU 168.A N THR 291.A O no hydrogen 2.964 N/A ASN 169.A ND2 ALA 148.A O no hydrogen 2.852 N/A THR 171.A N GLU 170.A OE1 no hydrogen 2.593 N/A THR 171.A OG1 GLU 170.A OE1 no hydrogen 3.292 N/A VAL 172.A N ILE 290.A O no hydrogen 3.030 N/A ILE 174.A N SER 288.A O no hydrogen 2.903 N/A ASN 175.A N ASN 187.A O no hydrogen 2.976 N/A CYS 176.A N CYS 286.A O no hydrogen 2.847 N/A THR 177.A N HIS 185.A O no hydrogen 2.833 N/A ARG 178.A N ILE 284.A O no hydrogen 2.797 N/A ARG 178.A NE ARG 178.A O no hydrogen 3.136 N/A ARG 178.A NE PRO 179.A O no hydrogen 2.909 N/A ARG 178.A NH1 ILE 181.A O no hydrogen 2.897 N/A ARG 178.A NH2 ILE 280.A O no hydrogen 2.812 N/A ARG 178.A NH2 GLY 282.A O no hydrogen 2.581 N/A ALA 184.A N CYS 259.A O no hydrogen 2.962 N/A HIS 185.A N THR 177.A O no hydrogen 2.926 N/A CYS 186.A N LEU 257.A O no hydrogen 2.931 N/A ASN 187.A N ASN 175.A O no hydrogen 2.809 N/A ILE 188.A N ILE 255.A O no hydrogen 2.988 N/A SER 189.A OG THR 192.A OG1 no hydrogen 2.920 N/A ARG 190.A N GLY 253.A O no hydrogen 3.084 N/A ARG 190.A NH2 THR 254.A O no hydrogen 3.249 N/A THR 192.A N SER 189.A OG no hydrogen 2.969 N/A THR 192.A OG1 SER 189.A OG no hydrogen 2.920 N/A TRP 193.A N SER 189.A O no hydrogen 3.168 N/A TRP 193.A NE1 LEU 244.A O no hydrogen 2.747 N/A ASN 194.A N ARG 190.A O no hydrogen 2.937 N/A SER 195.A N ALA 191.A O no hydrogen 2.949 N/A SER 195.A OG ALA 191.A O no hydrogen 3.170 N/A THR 196.A N THR 192.A O no hydrogen 2.984 N/A THR 196.A OG1 THR 192.A O no hydrogen 3.089 N/A LEU 197.A N TRP 193.A O no hydrogen 2.895 N/A LYS 198.A N ASN 194.A O no hydrogen 2.880 N/A LYS 199.A N SER 195.A O no hydrogen 3.001 N/A ILE 200.A N THR 196.A O no hydrogen 2.954 N/A VAL 201.A N LEU 197.A O no hydrogen 2.788 N/A ALA 202.A N LYS 198.A O no hydrogen 3.014 N/A LYS 203.A N LYS 199.A O no hydrogen 3.064 N/A LYS 203.A NZ GLU 149.A OE1 no hydrogen 3.073 N/A LYS 203.A NZ GLU 206.A OE2 no hydrogen 3.187 N/A LEU 204.A N ILE 200.A O no hydrogen 2.867 N/A ARG 205.A N VAL 201.A O no hydrogen 2.864 N/A ARG 205.A NE LYS 211.A O no hydrogen 3.495 N/A GLU 206.A N ALA 202.A O no hydrogen 2.993 N/A GLN 207.A N LYS 203.A O no hydrogen 3.026 N/A PHE 208.A N LEU 204.A O no hydrogen 2.796 N/A GLY 209.A N ARG 205.A O no hydrogen 2.978 N/A LYS 211.A N GLY 209.A O no hydrogen 2.292 N/A THR 212.A OG1 ASN 250.A OD1 no hydrogen 2.646 N/A ILE 213.A N TRP 249.A O no hydrogen 2.952 N/A VAL 214.A N GLU 309.A O no hydrogen 2.920 N/A PHE 215.A N SER 247.A O no hydrogen 2.851 N/A GLN 216.A N PHE 311.A O no hydrogen 3.017 N/A SER 218.A OG ILE 225.A O no hydrogen 2.895 N/A GLU 224.A N GLU 224.A OE1 no hydrogen 2.697 N/A ILE 225.A N ASP 222.A O no hydrogen 2.898 N/A VAL 226.A N ASP 222.A O no hydrogen 3.005 N/A MET 227.A N PRO 223.A O no hydrogen 2.950 N/A HIS 228.A N CYS 239.A O no hydrogen 2.871 N/A HIS 228.A ND1 THR 137.A O no hydrogen 2.812 N/A SER 229.A N THR 137.A OG1 no hydrogen 2.971 N/A SER 229.A OG THR 137.A OG1 no hydrogen 2.979 N/A PHE 230.A N PHE 237.A O no hydrogen 2.989 N/A CYS 232.A N GLU 235.A O no hydrogen 2.911 N/A GLY 234.A N ASN 231.A OD1 no hydrogen 2.849 N/A GLU 235.A N CYS 232.A O no hydrogen 2.906 N/A PHE 237.A N PHE 230.A O no hydrogen 2.857 N/A TYR 238.A N ARG 260.A O no hydrogen 2.869 N/A TYR 238.A OH GLU 224.A OE2 no hydrogen 2.711 N/A CYS 239.A N HIS 228.A O no hydrogen 2.823 N/A ASN 240.A N PRO 258.A O no hydrogen 2.951 N/A THR 241.A OG1 GLN 138.A OE1 no hydrogen 2.482 N/A THR 242.A N ASN 240.A OD1 no hydrogen 2.978 N/A THR 242.A OG1 ASN 240.A OD1 no hydrogen 2.883 N/A GLN 243.A NE2 THR 256.A O no hydrogen 2.744 N/A LEU 244.A N THR 241.A O no hydrogen 2.997 N/A PHE 245.A N THR 242.A O no hydrogen 3.234 N/A SER 247.A N PHE 215.A O no hydrogen 3.003 N/A TRP 249.A N ILE 213.A O no hydrogen 2.832 N/A SER 251.A OG SER 251.A O no hydrogen 2.500 N/A ILE 255.A N ILE 188.A O no hydrogen 2.823 N/A THR 256.A OG1 ASN 187.A OD1 no hydrogen 3.083 N/A LEU 257.A N CYS 186.A O no hydrogen 2.793 N/A CYS 259.A N ALA 184.A O no hydrogen 2.843 N/A CYS 259.A SG LEU 257.A O no hydrogen 3.591 N/A ARG 260.A N TYR 238.A O no hydrogen 2.921 N/A ILE 261.A N ARG 182.A O no hydrogen 2.570 N/A LYS 262.A N PHE 236.A O no hydrogen 2.966 N/A ILE 265.A N ALA 274.A O no hydrogen 2.903 N/A ASN 266.A N GLU 224.A OE2 no hydrogen 2.511 N/A ASN 266.A ND2 GLU 224.A OE1 no hydrogen 2.894 N/A MET 267.A N GLY 272.A O no hydrogen 3.150 N/A GLN 269.A N GLN 269.A OE1 no hydrogen 2.935 N/A GLN 269.A NE2 ASP 66.A OD1 no hydrogen 3.401 N/A LYS 273.A N LEU 75.A O no hydrogen 2.912 N/A ALA 274.A N ILE 265.A O no hydrogen 2.876 N/A MET 275.A N VAL 73.A O no hydrogen 2.837 N/A TYR 276.A N GLN 263.A O no hydrogen 3.026 N/A ILE 280.A N GLU 235.A OE2 no hydrogen 3.225 N/A GLN 283.A NE2 THR 177.A OG1 no hydrogen 3.347 N/A ILE 284.A N ARG 178.A O no hydrogen 2.939 N/A CYS 286.A N CYS 176.A O no hydrogen 2.874 N/A SER 287.A OG ASN 175.A OD1 no hydrogen 2.567 N/A SER 288.A N ILE 174.A O no hydrogen 2.935 N/A ASN 289.A N ASN 142.A OD1 no hydrogen 3.129 N/A ILE 290.A N VAL 172.A O no hydrogen 2.841 N/A THR 291.A N LEU 140.A O no hydrogen 2.919 N/A GLY 292.A N LEU 140.A O no hydrogen 3.310 N/A LEU 293.A N ILE 166.A O no hydrogen 2.942 N/A LEU 294.A N GLN 138.A O no hydrogen 2.937 N/A LEU 295.A N ILE 164.A O no hydrogen 2.920 N/A THR 296.A N ARG 312.A O no hydrogen 2.872 N/A ARG 297.A NH2 PHE 157.A O no hydrogen 2.930 N/A ASP 298.A N ILE 310.A O no hydrogen 2.797 N/A ASN 302.A ND2 ASN 303.A O no hydrogen 3.277 N/A GLU 309.A N THR 212.A O no hydrogen 2.963 N/A PHE 311.A N VAL 214.A O no hydrogen 2.910 N/A ARG 312.A N THR 296.A O no hydrogen 2.918 N/A ARG 312.A NE ASP 298.A OD1 no hydrogen 2.786 N/A ARG 312.A NE ASP 298.A OD2 no hydrogen 3.191 N/A ARG 312.A NH1 PRO 217.A O no hydrogen 2.862 N/A ARG 312.A NH2 ASP 298.A OD2 no hydrogen 2.757 N/A GLY 314.A N LEU 294.A O no hydrogen 2.732 N/A ARG 319.A N ASP 317.A OD1 no hydrogen 2.997 N/A ASP 320.A N ASP 317.A O no hydrogen 3.123 N/A ASN 321.A ND2 VAL 134.A O no hydrogen 3.554 N/A ASN 321.A ND2 SER 136.A O no hydrogen 3.144 N/A TRP 322.A N MET 318.A O no hydrogen 3.023 N/A TRP 322.A NE1 GLN 58.A OE1 no hydrogen 2.478 N/A ARG 323.A N ARG 319.A O no hydrogen 2.902 N/A ARG 323.A NE MET 48.A O no hydrogen 3.391 N/A ARG 323.A NH1 ASP 320.A OD1 no hydrogen 3.345 N/A SER 324.A N ASP 320.A O no hydrogen 3.010 N/A SER 324.A N ASN 321.A O no hydrogen 3.223 N/A SER 324.A OG ASN 321.A O no hydrogen 2.493 N/A GLU 325.A N TRP 322.A O no hydrogen 2.893 N/A LEU 326.A N TRP 322.A O no hydrogen 2.863 N/A TYR 329.A N LEU 326.A O no hydrogen 3.198 N/A TYR 329.A OH HIS 129.A ND1 no hydrogen 2.519 N/A LYS 330.A N LEU 106.A O no hydrogen 2.959 N/A LYS 330.A NZ GLU 2.A OE2 no hydrogen 2.603 N/A LYS 330.A NZ GLU 44.A OE1 no hydrogen 2.157 N/A LYS 330.A NZ ASN 45.A O no hydrogen 2.638 N/A VAL 332.A N ALA 104.A O no hydrogen 2.847 N/A LYS 333.A N LYS 1.A O no hydrogen 2.613 N/A ILE 334.A N GLY 102.A O no hydrogen 3.157 N/A