Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4yp9_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TRP 7.A N PRO 136.A O no hydrogen 2.759 N/A TRP 7.A NE1 ASP 141.A OD1 no hydrogen 3.195 N/A GLY 8.A N GLU 11.A OE1 no hydrogen 2.803 N/A PHE 12.A N GLY 8.A O no hydrogen 2.508 N/A LEU 13.A N TYR 9.A O no hydrogen 2.930 N/A ASP 14.A N GLN 10.A O no hydrogen 2.796 N/A GLU 15.A N GLU 11.A O no hydrogen 2.862 N/A PHE 16.A N PHE 12.A O no hydrogen 2.957 N/A GLN 19.A N PHE 16.A O no hydrogen 2.680 N/A ARG 20.A N PHE 16.A O no hydrogen 3.382 N/A ARG 20.A NH1 GLN 10.A OE1 no hydrogen 3.365 N/A ARG 20.A NH2 GLN 10.A OE1 no hydrogen 2.676 N/A ARG 20.A NH2 ASP 14.A OD1 no hydrogen 3.179 N/A ASN 21.A N PRO 17.A O no hydrogen 2.914 N/A LEU 22.A N GLU 18.A O no hydrogen 2.867 N/A THR 23.A N GLN 19.A O no hydrogen 2.834 N/A THR 23.A OG1 GLN 19.A O no hydrogen 3.022 N/A THR 23.A OG1 VAL 308.A O no hydrogen 2.686 N/A ASN 24.A N ARG 20.A O no hydrogen 2.856 N/A ALA 25.A N ASN 21.A O no hydrogen 2.894 N/A LEU 26.A N LEU 22.A O no hydrogen 2.752 N/A SER 27.A N THR 23.A O no hydrogen 2.839 N/A SER 27.A OG THR 23.A O no hydrogen 3.116 N/A GLU 28.A N ASN 24.A O no hydrogen 2.913 N/A ALA 29.A N ALA 25.A O no hydrogen 2.874 N/A VAL 30.A N LEU 26.A O no hydrogen 2.711 N/A ARG 31.A N SER 27.A O no hydrogen 2.879 N/A ALA 32.A N GLU 28.A O no hydrogen 2.976 N/A LEU 37.A N LEU 74.A O no hydrogen 2.786 N/A SER 38.A N GLU 301.A OE2 no hydrogen 3.107 N/A THR 41.A OG1 ARG 43.A O no hydrogen 2.929 N/A ILE 45.A N ASN 77.A O no hydrogen 3.081 N/A LYS 46.A N ASP 102.A OD2 no hydrogen 3.171 N/A LYS 46.A NZ LYS 100.A O no hydrogen 3.262 N/A ILE 47.A N GLN 79.A O no hydrogen 2.855 N/A SER 48.A N TYR 103.A O no hydrogen 2.878 N/A SER 48.A OG SER 99.A OG no hydrogen 3.405 N/A SER 48.A OG SER 101.A OG no hydrogen 2.556 N/A VAL 49.A N ASN 81.A O no hydrogen 2.793 N/A VAL 50.A N ILE 105.A O no hydrogen 2.960 N/A TYR 51.A N VAL 83.A O no hydrogen 2.993 N/A GLY 53.A N THR 85.A O no hydrogen 2.851 N/A VAL 56.A N ASP 240.A OD2 no hydrogen 2.879 N/A SER 57.A N ASP 240.A OD1 no hydrogen 3.090 N/A TYR 59.A OH GLN 131.A OE1 no hydrogen 2.312 N/A ARG 62.A N ASP 58.A O no hydrogen 3.082 N/A ARG 62.A NE ASP 58.A OD2 no hydrogen 3.202 N/A ARG 62.A NH1 SER 336.A OG no hydrogen 3.199 N/A ARG 62.A NH2 SER 266.A OG no hydrogen 2.745 N/A ASN 63.A N TYR 59.A O no hydrogen 2.795 N/A ASN 63.A ND2 THR 288.A OG1 no hydrogen 2.779 N/A ILE 64.A N TRP 60.A O no hydrogen 2.855 N/A ALA 65.A N VAL 61.A O no hydrogen 2.887 N/A SER 66.A N ARG 62.A O no hydrogen 2.873 N/A SER 66.A OG ARG 62.A O no hydrogen 2.798 N/A SER 66.A OG ASN 63.A O no hydrogen 3.048 N/A PHE 67.A N ASN 63.A O no hydrogen 2.878 N/A GLU 68.A N ILE 64.A O no hydrogen 2.835 N/A LYS 69.A N ALA 65.A O no hydrogen 2.886 N/A ARG 70.A N SER 66.A O no hydrogen 2.913 N/A ARG 70.A NE GLU 294.A OE1 no hydrogen 2.765 N/A ARG 70.A NH1 TYR 335.A OH no hydrogen 2.992 N/A ARG 70.A NH2 ALA 32.A O no hydrogen 3.160 N/A ARG 70.A NH2 GLU 294.A OE1 no hydrogen 3.034 N/A LEU 71.A N PHE 67.A O no hydrogen 2.829 N/A TYR 72.A N GLU 68.A O no hydrogen 2.859 N/A LYS 73.A N LYS 69.A O no hydrogen 2.884 N/A LEU 74.A N ARG 70.A O no hydrogen 2.895 N/A LEU 74.A N LEU 71.A O no hydrogen 3.052 N/A ASN 75.A N TYR 72.A O no hydrogen 2.942 N/A ILE 76.A N LEU 71.A O no hydrogen 3.394 N/A TYR 78.A OH GLU 68.A OE2 no hydrogen 2.973 N/A GLN 79.A N ILE 45.A O no hydrogen 2.817 N/A ASN 81.A N ILE 47.A O no hydrogen 2.813 N/A VAL 83.A N VAL 49.A O no hydrogen 2.812 N/A THR 85.A N TYR 51.A O no hydrogen 2.940 N/A THR 85.A OG1 TYR 51.A O no hydrogen 2.692 N/A ASN 88.A N ARG 86.A O no hydrogen 2.371 N/A SER 92.A OG SER 90.A O no hydrogen 3.244 N/A MET 94.A N LEU 91.A O no hydrogen 3.015 N/A LYS 98.A N GLU 95.A O no hydrogen 3.153 N/A SER 99.A OG SER 48.A OG no hydrogen 3.405 N/A SER 99.A OG SER 101.A OG no hydrogen 2.982 N/A LYS 100.A N LEU 97.A O no hydrogen 3.013 N/A SER 101.A OG SER 48.A OG no hydrogen 2.556 N/A SER 101.A OG SER 99.A OG no hydrogen 2.982 N/A ASP 102.A N LYS 46.A O no hydrogen 2.651 N/A TYR 103.A N LYS 46.A O no hydrogen 3.164 N/A TYR 103.A OH ASP 299.A OD2 no hydrogen 2.541 N/A LEU 104.A N LYS 127.A O no hydrogen 2.848 N/A ILE 105.A N SER 48.A O no hydrogen 2.767 N/A PHE 106.A N ILE 129.A O no hydrogen 2.919 N/A HIS 113.A N THR 110.A OG1 no hydrogen 3.319 N/A ARG 114.A N THR 110.A O no hydrogen 3.389 N/A LYS 115.A N THR 111.A O no hydrogen 2.886 N/A VAL 117.A N HIS 113.A O no hydrogen 2.818 N/A GLU 118.A N ARG 114.A O no hydrogen 2.891 N/A HIS 119.A N LYS 115.A O no hydrogen 2.899 N/A VAL 120.A N PHE 116.A O no hydrogen 2.806 N/A LEU 121.A N VAL 117.A O no hydrogen 2.796 N/A ASP 122.A N GLU 118.A O no hydrogen 2.903 N/A SER 123.A OG HIS 119.A ND1 no hydrogen 3.257 N/A SER 123.A OG HIS 119.A O no hydrogen 3.116 N/A THR 124.A OG1 VAL 120.A O no hydrogen 2.941 N/A THR 126.A N THR 124.A OG1 no hydrogen 3.274 N/A THR 126.A OG1 SER 101.A O no hydrogen 2.764 N/A LYS 127.A N ASP 102.A O no hydrogen 3.046 N/A LYS 127.A NZ ASP 299.A OD2 no hydrogen 3.082 N/A ILE 129.A N LEU 104.A O no hydrogen 2.757 N/A LEU 130.A N LEU 147.A O no hydrogen 2.826 N/A GLN 131.A N PHE 106.A O no hydrogen 2.912 N/A GLN 131.A NE2 ASN 63.A OD1 no hydrogen 2.954 N/A ASN 132.A N VAL 149.A O no hydrogen 2.548 N/A THR 134.A OG1 ASP 152.A OD1 no hydrogen 2.469 N/A THR 135.A OG1 THR 135.A O no hydrogen 2.574 N/A THR 135.A OG1 TYR 183.A OH no hydrogen 2.554 N/A VAL 137.A N TYR 148.A OH no hydrogen 3.255 N/A ARG 138.A N GLY 5.A O no hydrogen 3.183 N/A ARG 138.A NE TYR 6.A O no hydrogen 3.436 N/A TRP 140.A N VAL 137.A O no hydrogen 3.261 N/A ASP 141.A N ARG 138.A O no hydrogen 3.009 N/A GLN 144.A NE2 VAL 137.A O no hydrogen 2.604 N/A LEU 147.A N LEU 128.A O no hydrogen 3.329 N/A TYR 148.A N THR 307.A O no hydrogen 2.702 N/A TYR 148.A OH GLN 144.A OE1 no hydrogen 2.649 N/A VAL 149.A N LEU 130.A O no hydrogen 2.826 N/A GLY 150.A N TYR 309.A O no hydrogen 3.314 N/A ASP 152.A N SER 310.A OG no hydrogen 3.111 N/A HIS 153.A NE2 ASN 132.A O no hydrogen 2.984 N/A GLU 155.A N ASP 152.A OD2 no hydrogen 3.141 N/A GLY 156.A N ASP 152.A O no hydrogen 3.114 N/A SER 157.A N HIS 153.A O no hydrogen 2.888 N/A SER 157.A OG HIS 153.A O no hydrogen 2.626 N/A SER 157.A OG ARG 188.A O no hydrogen 3.370 N/A ARG 158.A N ALA 154.A O no hydrogen 2.744 N/A ARG 158.A NE GLU 155.A OE1 no hydrogen 3.398 N/A ARG 158.A NH2 GLU 155.A OE1 no hydrogen 3.539 N/A GLU 159.A N GLU 155.A O no hydrogen 2.894 N/A LEU 160.A N GLY 156.A O no hydrogen 3.360 N/A ALA 161.A N SER 157.A O no hydrogen 2.856 N/A THR 162.A N ARG 158.A O no hydrogen 2.790 N/A THR 162.A OG1 ARG 158.A O no hydrogen 3.177 N/A GLU 163.A N GLU 159.A O no hydrogen 2.995 N/A PHE 164.A N LEU 160.A O no hydrogen 2.880 N/A GLY 165.A N ALA 161.A O no hydrogen 2.806 N/A LYS 166.A N THR 162.A O no hydrogen 2.819 N/A LYS 166.A NZ GLU 163.A OE1 no hydrogen 2.900 N/A PHE 167.A N GLU 163.A O no hydrogen 2.881 N/A PHE 168.A N PHE 164.A O no hydrogen 2.692 N/A HIS 171.A N ASN 201.A O no hydrogen 2.683 N/A THR 172.A OG1 PRO 169.A O no hydrogen 2.528 N/A TYR 173.A N ASP 232.A OD2 no hydrogen 3.264 N/A TYR 174.A N GLU 203.A O no hydrogen 3.280 N/A SER 175.A N PHE 233.A O no hydrogen 3.372 N/A SER 175.A OG SER 206.A OG no hydrogen 2.840 N/A VAL 176.A N SER 206.A O no hydrogen 2.957 N/A LEU 177.A N TYR 235.A O no hydrogen 2.822 N/A TYR 178.A N TYR 208.A O no hydrogen 2.880 N/A TYR 178.A OH ASP 190.A OD1 no hydrogen 2.975 N/A TYR 183.A N ASP 109.A O no hydrogen 2.559 N/A TYR 183.A OH THR 135.A OG1 no hydrogen 2.554 N/A ILE 184.A N ASP 109.A OD1 no hydrogen 3.136 N/A SER 185.A OG SER 180.A O no hydrogen 2.504 N/A ASP 186.A N GLY 182.A O no hydrogen 3.049 N/A VAL 187.A N TYR 183.A O no hydrogen 2.921 N/A ARG 188.A N ILE 184.A O no hydrogen 2.785 N/A ARG 188.A NE HIS 153.A ND1 no hydrogen 3.048 N/A ARG 188.A NH1 CYS 237.A O no hydrogen 2.832 N/A GLY 189.A N SER 185.A O no hydrogen 2.736 N/A ASP 190.A N ASP 186.A O no hydrogen 2.864 N/A THR 191.A N VAL 187.A O no hydrogen 2.916 N/A THR 191.A OG1 VAL 187.A O no hydrogen 2.348 N/A ILE 193.A N GLY 189.A O no hydrogen 2.902 N/A HIS 194.A N ASP 190.A O no hydrogen 2.788 N/A GLN 195.A N THR 191.A O no hydrogen 2.997 N/A GLN 195.A NE2 ARG 158.A O no hydrogen 3.478 N/A GLN 195.A NE2 THR 162.A OG1 no hydrogen 3.098 N/A VAL 196.A N PHE 192.A O no hydrogen 2.910 N/A ASN 197.A N ILE 193.A O no hydrogen 2.809 N/A ARG 198.A N HIS 194.A O no hydrogen 2.833 N/A ASP 199.A N GLN 195.A O no hydrogen 2.922 N/A PHE 202.A N VAL 196.A O no hydrogen 3.118 N/A GLU 203.A N THR 172.A O no hydrogen 3.104 N/A GLN 205.A N TYR 174.A O no hydrogen 2.740 N/A GLN 205.A NE2 GLU 203.A O no hydrogen 2.979 N/A SER 206.A OG SER 175.A OG no hydrogen 2.840 N/A SER 206.A OG SER 224.A OG no hydrogen 3.218 N/A TYR 208.A N VAL 176.A O no hydrogen 2.975 N/A THR 210.A N PHE 179.A O no hydrogen 3.070 N/A THR 210.A OG1 TYR 178.A O no hydrogen 2.858 N/A LYS 211.A N SER 216.A OG no hydrogen 2.751 N/A ALA 212.A N THR 210.A OG1 no hydrogen 3.330 N/A GLN 215.A NE2 ASP 219.A OD1 no hydrogen 3.317 N/A GLN 215.A NE2 ASP 219.A OD2 no hydrogen 3.471 N/A SER 216.A N THR 213.A OG1 no hydrogen 2.945 N/A GLY 217.A N THR 213.A O no hydrogen 2.835 N/A TYR 218.A N LYS 214.A O no hydrogen 2.890 N/A TYR 218.A OH GLU 251.A OE1 no hydrogen 2.545 N/A TYR 218.A OH GLU 251.A OE2 no hydrogen 3.389 N/A ASP 219.A N GLN 215.A O no hydrogen 2.873 N/A ALA 220.A N SER 216.A O no hydrogen 2.865 N/A ALA 221.A N GLY 217.A O no hydrogen 2.869 N/A LYS 222.A N TYR 218.A O no hydrogen 2.932 N/A LYS 222.A NZ TYR 218.A OH no hydrogen 3.403 N/A ALA 223.A N ASP 219.A O no hydrogen 2.864 N/A SER 224.A N ALA 220.A O no hydrogen 2.865 N/A SER 224.A OG SER 206.A OG no hydrogen 3.218 N/A LEU 225.A N ALA 221.A O no hydrogen 2.881 N/A ALA 226.A N LYS 222.A O no hydrogen 2.836 N/A LYS 227.A N ALA 223.A O no hydrogen 2.953 N/A HIS 228.A N SER 224.A O no hydrogen 2.650 N/A ASP 232.A N TYR 173.A O no hydrogen 2.731 N/A ILE 234.A N MET 258.A O no hydrogen 2.857 N/A TYR 235.A N SER 175.A O no hydrogen 2.871 N/A TYR 235.A OH ARG 188.A O no hydrogen 2.818 N/A ALA 236.A N ASN 260.A OD1 no hydrogen 2.895 N/A CYS 237.A N LEU 177.A O no hydrogen 3.020 N/A CYS 237.A SG LEU 177.A O no hydrogen 3.474 N/A THR 239.A OG1 TRP 262.A O no hydrogen 3.481 N/A THR 239.A OG1 GLU 268.A OE1 no hydrogen 2.534 N/A ALA 242.A N SER 238.A O no hydrogen 2.818 N/A LEU 243.A N THR 239.A O no hydrogen 2.818 N/A GLY 244.A N ASP 240.A O no hydrogen 2.864 N/A ALA 245.A N VAL 241.A O no hydrogen 2.880 N/A VAL 246.A N ALA 242.A O no hydrogen 2.787 N/A ALA 248.A N GLY 244.A O no hydrogen 2.947 N/A LEU 249.A N ALA 245.A O no hydrogen 2.870 N/A ALA 250.A N VAL 246.A O no hydrogen 2.915 N/A GLU 251.A N ASP 247.A O no hydrogen 2.798 N/A LEU 252.A N ALA 248.A O no hydrogen 2.872 N/A GLY 253.A N ALA 250.A O no hydrogen 3.339 N/A ARG 254.A N LEU 249.A O no hydrogen 3.017 N/A ARG 254.A NE ASP 256.A OD1 no hydrogen 2.858 N/A ARG 254.A NH1 PRO 229.A O no hydrogen 2.722 N/A ARG 254.A NH2 PRO 229.A O no hydrogen 2.831 N/A ARG 254.A NH2 ASP 256.A OD1 no hydrogen 3.559 N/A ARG 254.A NH2 ASP 256.A OD2 no hydrogen 2.803 N/A MET 258.A N ASP 232.A O no hydrogen 3.311 N/A ILE 259.A N ASP 278.A OD2 no hydrogen 2.927 N/A ASN 260.A ND2 ALA 236.A O no hydrogen 2.911 N/A ASN 260.A ND2 GLY 261.A O no hydrogen 2.502 N/A GLY 261.A N ILE 279.A O no hydrogen 2.860 N/A TRP 262.A N GLU 268.A OE1 no hydrogen 3.190 N/A TRP 262.A N GLU 268.A OE2 no hydrogen 2.973 N/A TRP 262.A NE1 TYR 235.A OH no hydrogen 3.042 N/A GLY 263.A N VAL 281.A O no hydrogen 2.756 N/A GLY 264.A N GLU 268.A OE2 no hydrogen 3.117 N/A SER 266.A N ASP 58.A OD2 no hydrogen 2.949 N/A LEU 269.A N GLY 265.A O no hydrogen 3.104 N/A ASP 270.A N SER 266.A O no hydrogen 2.909 N/A ALA 271.A N ALA 267.A O no hydrogen 2.895 N/A ILE 272.A N GLU 268.A O no hydrogen 2.698 N/A GLN 273.A N LEU 269.A O no hydrogen 2.847 N/A LYS 274.A N ASP 270.A O no hydrogen 2.720 N/A LYS 274.A NZ ASP 276.A OD2 no hydrogen 3.373 N/A GLY 275.A N ILE 272.A O no hydrogen 2.996 N/A ASP 276.A N ALA 271.A O no hydrogen 2.874 N/A LEU 277.A N ALA 271.A O no hydrogen 3.362 N/A ASP 278.A N ILE 259.A O no hydrogen 3.121 N/A THR 280.A N VAL 316.A O no hydrogen 2.723 N/A THR 280.A OG1 GLU 268.A OE2 no hydrogen 2.825 N/A THR 280.A OG1 VAL 281.A O no hydrogen 3.447 N/A MET 282.A N GLU 314.A O no hydrogen 2.726 N/A ARG 283.A N GLY 263.A O no hydrogen 2.970 N/A MET 284.A N ASP 312.A O no hydrogen 2.878 N/A ASN 285.A ND2 ASP 286.A OD1 no hydrogen 2.986 N/A ASP 286.A N ALA 332.A O no hydrogen 2.969 N/A ASP 287.A N MET 284.A O no hydrogen 3.113 N/A THR 288.A OG1 ASN 285.A O no hydrogen 3.136 N/A ILE 290.A N ASP 286.A O no hydrogen 3.004 N/A ALA 291.A N ASP 287.A O no hydrogen 2.792 N/A MET 292.A N THR 288.A O no hydrogen 3.056 N/A ALA 293.A N GLY 289.A O no hydrogen 3.450 N/A GLU 294.A N ILE 290.A O no hydrogen 3.149 N/A ALA 295.A N ALA 291.A O no hydrogen 2.945 N/A ILE 296.A N MET 292.A O no hydrogen 3.007 N/A LYS 297.A N ALA 293.A O no hydrogen 2.957 N/A LYS 297.A N GLU 294.A O no hydrogen 2.792 N/A LYS 297.A NZ VAL 35.A O no hydrogen 2.626 N/A LYS 297.A NZ GLU 294.A OE2 no hydrogen 3.432 N/A TRP 298.A N GLU 294.A O no hydrogen 3.062 N/A ASP 299.A N ALA 295.A O no hydrogen 3.078 N/A LEU 300.A N ILE 296.A O no hydrogen 3.147 N/A GLU 301.A N LYS 297.A O no hydrogen 2.935 N/A GLU 301.A N TRP 298.A O no hydrogen 3.033 N/A ASP 302.A N ASP 299.A O no hydrogen 3.097 N/A LYS 303.A N TRP 298.A O no hydrogen 2.726 N/A THR 307.A N GLN 19.A OE1 no hydrogen 3.144 N/A TYR 309.A N TYR 148.A O no hydrogen 2.999 N/A SER 310.A N TYR 9.A OH no hydrogen 2.751 N/A SER 310.A OG GLY 150.A O no hydrogen 3.469 N/A SER 310.A OG GLY 311.A O no hydrogen 3.546 N/A GLY 311.A N GLY 150.A O no hydrogen 3.161 N/A GLU 314.A N MET 282.A O no hydrogen 2.765 N/A VAL 316.A N THR 280.A O no hydrogen 2.883 N/A THR 317.A OG1 ASP 320.A OD1 no hydrogen 3.366 N/A LYS 318.A N ASP 278.A O no hydrogen 3.008 N/A LYS 318.A NZ ASP 278.A OD1 no hydrogen 3.054 N/A ALA 319.A N THR 317.A OG1 no hydrogen 3.111 N/A ASP 320.A N THR 317.A O no hydrogen 2.931 N/A ARG 324.A N SER 321.A OG no hydrogen 3.225 N/A ILE 325.A N SER 321.A O no hydrogen 3.131 N/A GLU 326.A N PRO 322.A O no hydrogen 2.883 N/A ALA 327.A N GLU 323.A O no hydrogen 2.878 N/A LEU 328.A N ARG 324.A O no hydrogen 2.865 N/A LYS 329.A N ILE 325.A O no hydrogen 2.888 N/A LYS 330.A N GLU 326.A O no hydrogen 2.870 N/A ARG 331.A N ALA 327.A O no hydrogen 2.896 N/A ARG 331.A NH2 ASP 287.A OD2 no hydrogen 2.978 N/A ALA 332.A N LEU 328.A O no hydrogen 2.695 N/A PHE 333.A N LYS 329.A O no hydrogen 2.752 N/A ARG 334.A NH2 VAL 30.A O no hydrogen 2.880 N/A ARG 334.A NH2 ASP 287.A OD1 no hydrogen 3.547 N/A TYR 335.A N ASP 286.A OD2 no hydrogen 2.733 N/A SER 336.A N ASP 286.A OD2 no hydrogen 2.852 N/A SER 336.A OG ASP 286.A OD1 no hydrogen 2.737 N/A SER 336.A OG ASP 286.A OD2 no hydrogen 3.157 N/A ASP 337.A N PHE 333.A O no hydrogen 2.780 N/A