Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4yux_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLY 2.A N GLU 4.A OE2 no hydrogen 3.136 N/A SER 3.A OG ASP 33.A OD1 no hydrogen 3.506 N/A SER 3.A OG ASP 33.A OD2 no hydrogen 2.621 N/A SER 3.A OG HIS 40.A NE2 no hydrogen 3.162 N/A GLU 4.A N GLU 4.A OE1 no hydrogen 2.721 N/A LEU 5.A N GLY 2.A O no hydrogen 3.345 N/A ILE 6.A N SER 3.A O no hydrogen 3.024 N/A SER 7.A N TRP 10.A O no hydrogen 2.814 N/A TRP 10.A N SER 7.A O no hydrogen 3.107 N/A PHE 11.A N LEU 25.A O no hydrogen 2.738 N/A ARG 12.A N LEU 5.A O no hydrogen 2.925 N/A ARG 12.A NE GLU 14.A OE2 no hydrogen 3.013 N/A ARG 12.A NH1 GLU 14.A OE2 no hydrogen 3.477 N/A GLU 13.A N MET 23.A O no hydrogen 2.773 N/A GLU 14.A N ARG 12.A O no hydrogen 2.822 N/A GLN 17.A N ASN 15.A OD1 no hydrogen 2.900 N/A GLN 17.A NE2 ASN 15.A OD1 no hydrogen 3.062 N/A TRP 18.A N ASN 15.A O no hydrogen 3.023 N/A TRP 18.A NE1 GLU 13.A O no hydrogen 2.910 N/A LEU 25.A N PHE 11.A O no hydrogen 3.002 N/A VAL 27.A N GLY 9.A O no hydrogen 2.761 N/A GLU 28.A N GLU 45.A O no hydrogen 2.738 N/A LYS 29.A N GLU 45.A O no hydrogen 3.256 N/A LEU 31.A N ILE 43.A O no hydrogen 2.792 N/A TYR 32.A N ILE 43.A O no hydrogen 3.109 N/A ALA 34.A N LEU 41.A O no hydrogen 3.000 N/A THR 36.A N GLN 39.A O no hydrogen 2.827 N/A THR 36.A OG1 GLN 39.A O no hydrogen 3.183 N/A THR 36.A OG1 ASP 119.A OD1 no hydrogen 3.343 N/A THR 36.A OG1 ASP 119.A OD2 no hydrogen 2.559 N/A PHE 38.A N THR 36.A OG1 no hydrogen 2.913 N/A GLN 39.A N THR 36.A OG1 no hydrogen 2.890 N/A GLN 39.A NE2 ASP 119.A OD2 no hydrogen 2.910 N/A HIS 40.A N ASP 59.A OD1 no hydrogen 2.752 N/A HIS 40.A NE2 ASP 33.A OD1 no hydrogen 2.722 N/A LEU 41.A N ALA 34.A O no hydrogen 2.978 N/A THR 42.A N ALA 57.A O no hydrogen 2.914 N/A THR 42.A OG1 ASP 33.A OD1 no hydrogen 2.585 N/A ILE 43.A N TYR 32.A O no hydrogen 2.684 N/A PHE 44.A N VAL 55.A O no hydrogen 2.915 N/A GLU 45.A N LYS 29.A O no hydrogen 2.774 N/A SER 46.A N GLY 53.A O no hydrogen 2.987 N/A SER 46.A OG GLY 53.A O no hydrogen 2.659 N/A ASP 47.A N ARG 26.A O no hydrogen 3.041 N/A LYS 49.A N ASP 47.A OD1 no hydrogen 2.854 N/A GLY 50.A N ASP 47.A O no hydrogen 2.877 N/A THR 54.A N ASP 66.A OD2 no hydrogen 2.784 N/A THR 54.A OG1 GLU 45.A OE1 no hydrogen 2.670 N/A THR 54.A OG1 ASP 66.A OD2 no hydrogen 3.075 N/A VAL 55.A N PHE 44.A O no hydrogen 2.822 N/A MET 56.A N VAL 64.A O no hydrogen 3.034 N/A ALA 57.A N THR 42.A O no hydrogen 2.767 N/A LEU 58.A N CYS 61.A O no hydrogen 2.907 N/A ASP 59.A N HIS 40.A O no hydrogen 2.842 N/A CYS 61.A N LEU 58.A O no hydrogen 2.913 N/A CYS 61.A SG ASP 59.A O no hydrogen 3.725 N/A ILE 62.A N GLU 13.A OE2 no hydrogen 2.758 N/A GLN 63.A N MET 56.A O no hydrogen 2.785 N/A GLN 63.A NE2 CYS 61.A O no hydrogen 3.011 N/A THR 65.A OG1 ASP 68.A OD1 no hydrogen 2.771 N/A ASP 66.A N THR 54.A O no hydrogen 2.969 N/A TYR 67.A N TRP 52.A O no hydrogen 3.346 N/A ASP 68.A N THR 65.A OG1 no hydrogen 3.247 N/A GLU 69.A N THR 65.A O no hydrogen 3.082 N/A VAL 71.A N ASP 68.A O no hydrogen 3.232 N/A TYR 72.A OH ASP 167.A OD1 no hydrogen 2.747 N/A HIS 73.A N GLU 69.A O no hydrogen 3.510 N/A HIS 73.A ND1 GLU 69.A OE2 no hydrogen 2.787 N/A GLU 74.A N PHE 70.A O no hydrogen 2.871 N/A VAL 75.A N VAL 71.A O no hydrogen 2.906 N/A LEU 76.A N TYR 72.A O no hydrogen 2.975 N/A GLY 77.A N HIS 73.A O no hydrogen 3.019 N/A HIS 78.A N GLU 74.A O no hydrogen 2.872 N/A HIS 78.A ND1 HIS 107.A NE2 no hydrogen 2.882 N/A HIS 78.A NE2 GLU 103.A OE1 no hydrogen 2.820 N/A THR 79.A N VAL 75.A O no hydrogen 2.899 N/A THR 79.A OG1 VAL 75.A O no hydrogen 2.647 N/A SER 80.A N LEU 76.A O no hydrogen 3.486 N/A SER 80.A OG LEU 76.A O no hydrogen 2.751 N/A SER 80.A OG GLY 77.A O no hydrogen 3.272 N/A LEU 81.A N GLY 77.A O no hydrogen 3.218 N/A CYS 82.A N HIS 78.A O no hydrogen 2.824 N/A CYS 82.A SG ARG 259.A O no hydrogen 3.362 N/A SER 83.A N SER 80.A O no hydrogen 2.996 N/A SER 83.A OG THR 79.A O no hydrogen 2.677 N/A SER 83.A OG VAL 254.A O no hydrogen 3.511 N/A HIS 84.A N LEU 81.A O no hydrogen 3.136 N/A LYS 86.A N HIS 84.A ND1 no hydrogen 2.987 N/A GLU 88.A N ASP 162.A OD2 no hydrogen 2.828 N/A ARG 89.A N ASP 162.A OD2 no hydrogen 2.927 N/A VAL 90.A N HIS 112.A O no hydrogen 2.965 N/A LEU 91.A N VAL 163.A O no hydrogen 2.921 N/A ILE 92.A N ASP 114.A O no hydrogen 2.779 N/A ILE 93.A N ILE 165.A O no hydrogen 2.836 N/A GLY 94.A N VAL 116.A O no hydrogen 2.856 N/A GLY 95.A N ASP 167.A O no hydrogen 2.968 N/A GLY 96.A N ASP 117.A OD2 no hydrogen 2.825 N/A GLY 98.A N GLY 95.A O no hydrogen 2.928 N/A GLY 99.A N ASP 97.A OD1 no hydrogen 2.852 N/A ARG 102.A N GLY 98.A O no hydrogen 2.869 N/A ARG 102.A NE GLU 103.A OE2 no hydrogen 2.932 N/A ARG 102.A NH1 GLU 69.A OE1 no hydrogen 2.802 N/A ARG 102.A NH1 GLU 69.A OE2 no hydrogen 3.339 N/A ARG 102.A NH1 GLN 132.A O no hydrogen 2.949 N/A ARG 102.A NH2 GLU 69.A OE1 no hydrogen 3.398 N/A ARG 102.A NH2 GLU 69.A OE2 no hydrogen 2.791 N/A ARG 102.A NH2 GLU 103.A OE2 no hydrogen 2.897 N/A GLU 103.A N GLY 99.A O no hydrogen 3.164 N/A VAL 104.A N VAL 100.A O no hydrogen 2.903 N/A LEU 105.A N LEU 101.A O no hydrogen 2.845 N/A ARG 106.A N GLU 103.A O no hydrogen 3.072 N/A ARG 106.A NE GLU 103.A OE1 no hydrogen 2.859 N/A ARG 106.A NH2 GLU 103.A OE2 no hydrogen 3.566 N/A HIS 107.A N VAL 104.A O no hydrogen 3.047 N/A HIS 107.A NE2 HIS 78.A ND1 no hydrogen 2.882 N/A THR 109.A OG1 PRO 87.A O no hydrogen 2.814 N/A VAL 110.A N HIS 107.A O no hydrogen 3.189 N/A GLU 111.A N GLU 88.A O no hydrogen 2.710 N/A HIS 112.A N GLU 88.A O no hydrogen 3.102 N/A HIS 112.A NE2 ASP 114.A OD1 no hydrogen 2.675 N/A CYS 113.A N ARG 141.A O no hydrogen 2.841 N/A CYS 113.A SG VAL 90.A O no hydrogen 3.588 N/A CYS 113.A SG ASP 114.A O no hydrogen 3.613 N/A ASP 114.A N VAL 90.A O no hydrogen 2.909 N/A LEU 115.A N THR 143.A O no hydrogen 2.943 N/A VAL 116.A N ILE 92.A O no hydrogen 2.914 N/A ASP 117.A N ARG 145.A O no hydrogen 3.086 N/A ASP 119.A N ASP 117.A OD1 no hydrogen 2.882 N/A GLU 121.A N ASP 119.A OD1 no hydrogen 3.024 N/A VAL 122.A N ASP 119.A O no hydrogen 3.053 N/A GLU 124.A N GLY 120.A O no hydrogen 3.110 N/A GLN 125.A N GLU 121.A O no hydrogen 2.849 N/A GLN 125.A NE2 GLU 121.A OE2 no hydrogen 2.965 N/A SER 126.A N VAL 122.A O no hydrogen 2.844 N/A SER 126.A OG VAL 122.A O no hydrogen 2.579 N/A LYS 127.A N MET 123.A O no hydrogen 2.976 N/A GLN 128.A N GLU 124.A O no hydrogen 3.175 N/A HIS 129.A N GLN 125.A O no hydrogen 2.873 N/A PHE 130.A N SER 126.A O no hydrogen 2.888 N/A ILE 133.A N PHE 130.A O no hydrogen 2.896 N/A SER 134.A N PHE 130.A O no hydrogen 2.927 N/A SER 134.A OG SER 126.A O no hydrogen 2.907 N/A SER 134.A OG PHE 130.A O no hydrogen 3.043 N/A SER 136.A OG GLY 98.A O no hydrogen 2.836 N/A LEU 137.A N SER 134.A O no hydrogen 2.969 N/A ALA 138.A N ARG 135.A O no hydrogen 3.145 N/A ASP 139.A N SER 136.A O no hydrogen 3.040 N/A ARG 141.A N ASP 139.A OD1 no hydrogen 2.863 N/A ARG 141.A NE ASP 139.A OD1 no hydrogen 2.919 N/A ARG 141.A NH1 LEU 105.A O no hydrogen 2.818 N/A ARG 141.A NH2 LEU 105.A O no hydrogen 3.514 N/A ARG 141.A NH2 ASP 139.A OD2 no hydrogen 2.701 N/A ALA 142.A N ASP 139.A O no hydrogen 2.930 N/A THR 143.A N CYS 113.A O no hydrogen 2.958 N/A ARG 145.A N LEU 115.A O no hydrogen 2.831 N/A GLY 147.A N ASP 117.A O no hydrogen 2.978 N/A LEU 150.A N ASP 148.A OD1 no hydrogen 3.459 N/A ALA 151.A N ASP 148.A OD2 no hydrogen 2.854 N/A PHE 152.A N ASP 148.A O no hydrogen 3.081 N/A VAL 153.A N GLY 149.A O no hydrogen 3.018 N/A ARG 154.A N LEU 150.A O no hydrogen 3.142 N/A GLN 155.A N ALA 151.A O no hydrogen 3.222 N/A GLN 155.A N PHE 152.A O no hydrogen 3.081 N/A THR 156.A N VAL 153.A O no hydrogen 3.073 N/A THR 156.A OG1 PHE 152.A O no hydrogen 2.843 N/A ASN 159.A N ARG 189.A O no hydrogen 3.110 N/A THR 160.A N ILE 190.A O no hydrogen 2.793 N/A THR 160.A OG1 PRO 157.A O no hydrogen 2.827 N/A TYR 161.A N ILE 190.A O no hydrogen 3.078 N/A TYR 161.A OH ASP 114.A OD2 no hydrogen 2.636 N/A ASP 162.A N ARG 89.A O no hydrogen 2.779 N/A VAL 163.A N ARG 89.A O no hydrogen 3.375 N/A VAL 164.A N ILE 196.A O no hydrogen 2.938 N/A ILE 165.A N LEU 91.A O no hydrogen 2.775 N/A ILE 166.A N CYS 198.A O no hydrogen 2.800 N/A ASP 167.A N ILE 93.A O no hydrogen 2.768 N/A THR 168.A OG1 THR 169.A O no hydrogen 2.937 N/A ALA 172.A N GLN 17.A OE1 no hydrogen 3.151 N/A SER 176.A N GLY 173.A O no hydrogen 3.180 N/A LEU 178.A N ALA 175.A O no hydrogen 2.749 N/A PHE 179.A N SER 176.A O no hydrogen 3.225 N/A GLY 180.A N LYS 177.A O no hydrogen 3.095 N/A TYR 184.A N GLY 180.A O no hydrogen 3.347 N/A LYS 185.A N GLU 181.A O no hydrogen 2.958 N/A ASP 186.A N ALA 182.A O no hydrogen 3.363 N/A VAL 187.A N PHE 183.A O no hydrogen 3.016 N/A LEU 188.A N TYR 184.A O no hydrogen 2.997 N/A ARG 189.A N LYS 185.A O no hydrogen 3.181 N/A ARG 189.A NE ASP 186.A OD1 no hydrogen 3.137 N/A ARG 189.A NH1 THR 156.A O no hydrogen 3.073 N/A ARG 189.A NH1 ASP 186.A OD1 no hydrogen 3.014 N/A ARG 189.A NH2 THR 156.A O no hydrogen 2.843 N/A ARG 189.A NH2 ASP 158.A OD1 no hydrogen 2.845 N/A ILE 190.A N ASP 186.A O no hydrogen 2.872 N/A LEU 191.A N VAL 187.A O no hydrogen 3.199 N/A LEU 191.A N LEU 188.A O no hydrogen 3.343 N/A LYS 192.A N TYR 161.A O no hydrogen 2.836 N/A LYS 192.A NZ ASN 159.A O no hydrogen 2.901 N/A GLY 195.A N LYS 192.A O no hydrogen 2.848 N/A ILE 196.A N ASP 162.A O no hydrogen 3.040 N/A CYS 197.A N CYS 246.A O no hydrogen 2.992 N/A CYS 197.A SG CYS 198.A O no hydrogen 3.829 N/A CYS 198.A N VAL 164.A O no hydrogen 2.956 N/A CYS 198.A SG LEU 76.A O no hydrogen 3.745 N/A ASN 199.A N THR 243.A OG1 no hydrogen 3.085 N/A ASN 199.A ND2 TYR 184.A OH no hydrogen 2.877 N/A GLN 200.A NE2 GLU 202.A OE1 no hydrogen 3.450 N/A GLY 201.A N GLY 242.A O no hydrogen 2.740 N/A SER 203.A N ASP 207.A OD2 no hydrogen 2.984 N/A TRP 205.A N SER 203.A OG no hydrogen 2.990 N/A LEU 206.A N SER 203.A O no hydrogen 3.273 N/A LEU 206.A N SER 203.A OG no hydrogen 3.265 N/A ASP 207.A N SER 203.A O no hydrogen 2.782 N/A ILE 211.A N ASP 207.A O no hydrogen 2.936 N/A GLU 212.A N LEU 208.A O no hydrogen 2.837 N/A LYS 213.A N GLU 209.A O no hydrogen 2.936 N/A MET 214.A N LEU 210.A O no hydrogen 2.817 N/A SER 215.A N ILE 211.A O no hydrogen 2.911 N/A ARG 216.A N GLU 212.A O no hydrogen 3.070 N/A PHE 217.A N LYS 213.A O no hydrogen 2.907 N/A ILE 218.A N MET 214.A O no hydrogen 2.836 N/A ARG 219.A N SER 215.A O no hydrogen 3.217 N/A ARG 219.A NH2 VAL 226.A O no hydrogen 3.550 N/A GLU 220.A N ARG 216.A O no hydrogen 2.934 N/A THR 221.A N PHE 217.A O no hydrogen 2.731 N/A GLY 222.A N ARG 219.A O no hydrogen 3.062 N/A PHE 223.A N ILE 218.A O no hydrogen 3.355 N/A ALA 224.A N SER 247.A O no hydrogen 2.773 N/A SER 225.A N SER 247.A O no hydrogen 3.382 N/A GLN 227.A N VAL 245.A O no hydrogen 2.919 N/A GLN 227.A NE2 VAL 226.A O no hydrogen 3.255 N/A GLN 227.A NE2 ASN 292.A O no hydrogen 3.121 N/A TYR 228.A N ASN 292.A OD1 no hydrogen 2.694 N/A TYR 228.A OH GLY 201.A O no hydrogen 3.248 N/A TYR 228.A OH GLU 202.A O no hydrogen 2.754 N/A ALA 229.A N THR 243.A O no hydrogen 2.811 N/A LEU 230.A N SER 281.A O no hydrogen 2.790 N/A MET 231.A N ILE 241.A O no hydrogen 2.839 N/A HIS 232.A N TYR 272.A OH no hydrogen 3.100 N/A VAL 233.A N GLY 239.A O no hydrogen 3.078 N/A THR 235.A N ASP 68.A OD2 no hydrogen 3.149 N/A THR 235.A OG1 ASP 68.A OD1 no hydrogen 3.265 N/A THR 235.A OG1 ASP 68.A OD2 no hydrogen 2.728 N/A TYR 236.A N VAL 233.A O no hydrogen 3.270 N/A TYR 236.A OH ASP 170.A OD1 no hydrogen 2.591 N/A TYR 236.A OH ASP 170.A OD2 no hydrogen 3.063 N/A TYR 236.A OH GLU 202.A OE1 no hydrogen 3.312 N/A CYS 238.A SG GLN 21.A OE1 no hydrogen 3.484 N/A GLY 239.A N TYR 236.A O no hydrogen 2.758 N/A ILE 241.A N MET 231.A O no hydrogen 3.286 N/A GLY 242.A N GLU 202.A O no hydrogen 3.010 N/A THR 243.A N ALA 229.A O no hydrogen 2.944 N/A THR 243.A OG1 ASN 199.A O no hydrogen 2.691 N/A LEU 244.A N ASN 199.A OD1 no hydrogen 2.919 N/A VAL 245.A N GLN 227.A O no hydrogen 2.805 N/A CYS 246.A N CYS 197.A O no hydrogen 2.766 N/A CYS 246.A SG LEU 244.A O no hydrogen 3.569 N/A SER 247.A N SER 225.A O no hydrogen 2.980 N/A SER 247.A OG LYS 249.A O no hydrogen 2.849 N/A LYS 248.A N GLY 195.A O no hydrogen 2.979 N/A LYS 248.A NZ LEU 188.A O no hydrogen 2.826 N/A LYS 248.A NZ LEU 191.A O no hydrogen 2.806 N/A THR 255.A N ASP 253.A OD1 no hydrogen 3.014 N/A THR 255.A OG1 ASP 253.A OD1 no hydrogen 2.727 N/A THR 255.A OG1 ASP 253.A OD2 no hydrogen 3.487 N/A LYS 256.A NZ THR 255.A OG1 no hydrogen 3.121 N/A ARG 259.A N CYS 82.A O no hydrogen 2.958 N/A ARG 259.A NE HIS 84.A O no hydrogen 2.744 N/A ARG 259.A NH2 LEU 81.A O no hydrogen 3.087 N/A GLU 262.A N GLU 262.A OE1 no hydrogen 2.838 N/A ASP 263.A N PRO 260.A O no hydrogen 3.227 N/A MET 264.A N VAL 261.A O no hydrogen 2.698 N/A ALA 267.A N MET 264.A O no hydrogen 3.254 N/A ASP 269.A N PHE 266.A O no hydrogen 2.943 N/A LEU 270.A N ALA 267.A O no hydrogen 3.311 N/A LYS 271.A N GLU 74.A OE2 no hydrogen 2.848 N/A TYR 272.A N GLU 74.A OE1 no hydrogen 2.789 N/A TYR 273.A N GLU 74.A OE1 no hydrogen 2.832 N/A TYR 273.A OH HIS 278.A ND1 no hydrogen 2.675 N/A SER 275.A N GLU 262.A OE2 no hydrogen 2.853 N/A SER 275.A OG GLU 262.A OE1 no hydrogen 2.597 N/A MET 277.A N ASP 274.A OD1 no hydrogen 2.831 N/A HIS 278.A N ASP 274.A O no hydrogen 2.877 N/A HIS 278.A ND1 TYR 273.A OH no hydrogen 2.675 N/A HIS 278.A NE2 VAL 254.A O no hydrogen 2.739 N/A LYS 279.A N SER 275.A O no hydrogen 3.184 N/A LYS 279.A NZ GLU 276.A OE1 no hydrogen 3.126 N/A LYS 279.A NZ GLU 276.A OE2 no hydrogen 3.167 N/A ALA 280.A N GLU 276.A O no hydrogen 2.921 N/A SER 281.A N MET 277.A O no hydrogen 2.954 N/A SER 281.A N HIS 278.A O no hydrogen 3.303 N/A SER 281.A OG HIS 278.A O no hydrogen 2.800 N/A PHE 282.A N LYS 279.A O no hydrogen 3.257 N/A ALA 283.A N ALA 280.A O no hydrogen 3.120 N/A ALA 288.A N PRO 285.A O no hydrogen 2.807 N/A ARG 289.A N ARG 286.A O no hydrogen 3.244 N/A ARG 289.A NH1 ARG 286.A O no hydrogen 2.921 N/A HIS 290.A NE2 GLU 212.A OE2 no hydrogen 2.766 N/A ILE 291.A N ALA 288.A O no hydrogen 3.119 N/A ASN 292.A N ARG 289.A O no hydrogen 2.877 N/A ASN 292.A ND2 TYR 228.A O no hydrogen 2.893 N/A ASN 292.A ND2 PHE 282.A O no hydrogen 3.031 N/A ASN 293.A N ARG 289.A O no hydrogen 2.917 N/A