Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4z3v_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 4.A N GLY 1.A O no hydrogen 3.148 N/A GLY 5.A N GLU 8.A OE1.A no hydrogen 2.583 N/A GLU 8.A N GLY 5.A O no hydrogen 2.993 N/A ILE 9.A N VAL 75.A O no hydrogen 2.905 N/A LYS 12.A N ASP 10.A OD1 no hydrogen 2.903 N/A LYS 12.A NZ.A ASP 10.A OD1 no hydrogen 2.951 N/A LYS 12.A NZ.A ASP 10.A OD2 no hydrogen 3.457 N/A ASP 13.A N ASP 10.A O no hydrogen 2.902 N/A LEU 14.A N PRO 11.A O no hydrogen 3.066 N/A THR 15.A N LYS 32.A O no hydrogen 2.787 N/A LEU 17.A N TYR 30.A O no hydrogen 2.792 N/A LYS 18.A N TYR 30.A O no hydrogen 3.354 N/A LEU 20.A N VAL 28.A O no hydrogen 2.808 N/A GLY 23.A N GLY 26.A O no hydrogen 3.225 N/A GLY 26.A N GLY 23.A O no hydrogen 2.887 N/A VAL 28.A N GLY 21.A O no hydrogen 2.864 N/A LYS 29.A N ILE 41.A O no hydrogen 2.899 N/A TYR 30.A N LYS 18.A O no hydrogen 2.687 N/A TYR 30.A OH ASP 38.A OD1 no hydrogen 2.740 N/A GLY 31.A N VAL 39.A O no hydrogen 2.945 N/A LYS 32.A N THR 15.A O no hydrogen 2.861 N/A LYS 32.A NZ GLN 36.A O no hydrogen 3.370 N/A LYS 32.A NZ ASP 38.A OD1 no hydrogen 2.725 N/A TRP 33.A N TYR 37.A O no hydrogen 2.827 N/A ARG 34.A N ASP 13.A O no hydrogen 2.785 N/A ARG 34.A NE ASP 13.A OD2 no hydrogen 2.912 N/A ARG 34.A NH2 ASP 13.A OD2 no hydrogen 3.252 N/A GLN 36.A N TRP 33.A O no hydrogen 3.296 N/A TYR 37.A N TRP 33.A O no hydrogen 3.144 N/A VAL 39.A N GLY 31.A O no hydrogen 2.941 N/A ALA 40.A N THR 86.A O no hydrogen 2.829 N/A ILE 41.A N LYS 29.A O no hydrogen 2.743 N/A LYS 42.A N ILE 84.A O no hydrogen 2.815 N/A LYS 42.A NZ ASP 151.A OD2 no hydrogen 2.905 N/A MET 43.A N VAL 27.A O no hydrogen 2.974 N/A ILE 44.A N ILE 82.A O no hydrogen 3.058 N/A LYS 45.A N PHE 25.A O no hydrogen 2.878 N/A LYS 45.A NZ GLN 24.A O no hydrogen 3.418 N/A SER 48.A N LYS 45.A O no hydrogen 3.048 N/A SER 48.A OG LYS 45.A O no hydrogen 2.815 N/A SER 50.A N TYR 157.A O no hydrogen 2.808 N/A PHE 54.A N SER 50.A O no hydrogen 2.966 N/A ILE 55.A N GLU 51.A O no hydrogen 2.846 N/A GLU 56.A N ASP 52.A O no hydrogen 3.251 N/A GLU 57.A N GLU 53.A O no hydrogen 3.111 N/A ALA 58.A N PHE 54.A O no hydrogen 2.676 N/A LYS 59.A N GLU 56.A O no hydrogen 3.215 N/A LYS 59.A NZ GLU 56.A OE1 no hydrogen 3.268 N/A VAL 60.A N GLU 57.A O no hydrogen 2.917 N/A MET 61.A N GLU 57.A O no hydrogen 2.945 N/A MET 62.A N ALA 58.A O no hydrogen 2.849 N/A ASN 63.A N VAL 60.A O no hydrogen 3.094 N/A LEU 64.A N MET 61.A O no hydrogen 2.974 N/A SER 65.A N TYR 123.A OH no hydrogen 3.000 N/A SER 65.A OG.B GLN 71.A OE1 no hydrogen 2.894 N/A LYS 68.A N HIS 66.A ND1 no hydrogen 2.974 N/A LYS 68.A NZ ASP 116.A OD1 no hydrogen 2.798 N/A LYS 68.A NZ GLU 119.A OE1 no hydrogen 2.725 N/A LEU 69.A N HIS 66.A O no hydrogen 2.993 N/A VAL 70.A N VAL 149.A O no hydrogen 2.932 N/A GLN 71.A N GLU 87.A OE1 no hydrogen 3.025 N/A GLN 71.A NE2 LEU 64.A O no hydrogen 3.374 N/A GLN 71.A NE2 LEU 72.A O no hydrogen 3.164 N/A TYR 73.A N ILE 85.A O no hydrogen 2.781 N/A GLY 74.A N ILE 85.A O no hydrogen 3.361 N/A VAL 75.A N TRP 7.A O no hydrogen 2.880 N/A CYS 76.A N PHE 83.A O no hydrogen 2.827 N/A CYS 76.A SG ILE 9.A O no hydrogen 3.331 N/A THR 77.A N GLU 8.A OE2.B no hydrogen 2.639 N/A THR 77.A OG1 GLU 8.A OE1.B no hydrogen 2.623 N/A THR 77.A OG1 GLU 8.A OE2.A no hydrogen 2.522 N/A THR 77.A OG1 GLU 8.A OE2.B no hydrogen 2.691 N/A LYS 78.A NZ GLY 3.A O no hydrogen 2.670 N/A GLN 79.A NE2 PRO 81.A O no hydrogen 2.589 N/A ARG 80.A NH2 ASP 52.A OD1 no hydrogen 2.679 N/A PHE 83.A N CYS 76.A O no hydrogen 3.220 N/A ILE 84.A N LYS 42.A O no hydrogen 2.954 N/A ILE 85.A N GLY 74.A O no hydrogen 2.898 N/A THR 86.A N ALA 40.A O no hydrogen 2.929 N/A THR 86.A OG1 GLU 87.A O no hydrogen 3.345 N/A GLU 87.A N GLN 71.A O no hydrogen 2.895 N/A ASN 91.A N VAL 141.A O no hydrogen 2.846 N/A ASN 91.A ND2 ASN 142.A O no hydrogen 2.970 N/A GLY 92.A N MET 89.A O no hydrogen 3.152 N/A LEU 94.A N CYS 139.A O no hydrogen 2.855 N/A TYR 97.A N CYS 93.A O no hydrogen 3.113 N/A LEU 98.A N LEU 94.A O no hydrogen 2.857 N/A ARG 99.A N LEU 95.A O no hydrogen 3.270 N/A ARG 99.A NE GLY 206.A O no hydrogen 2.770 N/A ARG 99.A NH2 GLY 206.A O no hydrogen 2.916 N/A GLU 100.A N TYR 97.A O no hydrogen 3.195 N/A HIS 103.A N GLU 100.A O no hydrogen 3.343 N/A ARG 104.A N MET 101.A O no hydrogen 3.221 N/A GLN 106.A N GLN 109.A OE1 no hydrogen 2.842 N/A GLN 108.A N GLN 108.A OE1.A no hydrogen 2.861 N/A GLN 108.A NE2.A GLU 270.A O no hydrogen 3.518 N/A GLN 108.A NE2.B SER 271.A OG no hydrogen 3.370 N/A GLN 109.A N GLN 106.A O no hydrogen 3.019 N/A LEU 110.A N GLN 106.A O no hydrogen 3.281 N/A LEU 111.A N THR 107.A O no hydrogen 2.908 N/A GLU 112.A N GLN 108.A O no hydrogen 3.061 N/A MET 113.A N GLN 109.A O no hydrogen 3.069 N/A CYS 114.A N LEU 110.A O no hydrogen 3.131 N/A CYS 114.A SG LEU 110.A O no hydrogen 3.519 N/A LYS 115.A N LEU 111.A O no hydrogen 2.917 N/A LYS 115.A NZ GLU 119.A OE2 no hydrogen 2.819 N/A ASP 116.A N GLU 112.A O no hydrogen 2.904 N/A VAL 117.A N MET 113.A O no hydrogen 3.157 N/A CYS 118.A N CYS 114.A O no hydrogen 2.879 N/A CYS 118.A SG PHE 256.A O no hydrogen 3.520 N/A GLU 119.A N LYS 115.A O no hydrogen 2.839 N/A ALA 120.A N ASP 116.A O no hydrogen 3.238 N/A MET 121.A N VAL 117.A O no hydrogen 2.911 N/A GLU 122.A N CYS 118.A O no hydrogen 2.794 N/A TYR 123.A N GLU 119.A O no hydrogen 3.074 N/A LEU 124.A N ALA 120.A O no hydrogen 2.946 N/A GLU 125.A N MET 121.A O no hydrogen 2.814 N/A SER 126.A N GLU 122.A O no hydrogen 2.971 N/A SER 126.A OG TYR 123.A O no hydrogen 2.688 N/A LYS 127.A N TYR 123.A O no hydrogen 3.159 N/A LYS 127.A N LEU 124.A O no hydrogen 3.033 N/A GLN 128.A N GLU 125.A O no hydrogen 2.996 N/A PHE 129.A N LEU 124.A O no hydrogen 2.922 N/A HIS 131.A N ASP 191.A OD2 no hydrogen 2.772 N/A HIS 131.A NE2 SER 150.A O no hydrogen 2.905 N/A ARG 132.A N ASP 191.A OD1 no hydrogen 3.098 N/A ASP 133.A N HIS 131.A ND1 no hydrogen 3.039 N/A ALA 136.A N GLU 201.A OE2 no hydrogen 2.936 N/A ARG 137.A NH2 ASP 133.A OD1 no hydrogen 2.945 N/A ASN 138.A N ALA 135.A O no hydrogen 2.944 N/A ASN 138.A ND2 ASP 133.A O no hydrogen 2.762 N/A CYS 139.A N ALA 136.A O no hydrogen 3.080 N/A CYS 139.A SG ALA 135.A O no hydrogen 3.700 N/A LEU 140.A N LYS 148.A O no hydrogen 2.889 N/A VAL 141.A N GLY 92.A O no hydrogen 2.796 N/A ASN 142.A N VAL 146.A O no hydrogen 2.956 N/A GLN 144.A N ASN 142.A OD1 no hydrogen 2.892 N/A GLN 144.A NE2 ASP 143.A OD2 no hydrogen 3.406 N/A GLY 145.A N ASN 142.A O no hydrogen 3.016 N/A VAL 146.A N ASN 142.A OD1 no hydrogen 3.005 N/A VAL 147.A N ASP 116.A OD2 no hydrogen 3.032 N/A LYS 148.A N LEU 140.A O no hydrogen 2.830 N/A LYS 148.A NZ GLU 67.A O no hydrogen 2.925 N/A LYS 148.A NZ GLU 87.A OE2 no hydrogen 2.728 N/A VAL 149.A N LYS 68.A O no hydrogen 2.870 N/A SER 150.A N ASN 138.A O no hydrogen 2.893 N/A SER 150.A OG.A ASN 138.A O no hydrogen 3.004 N/A SER 150.A OG.A ASP 151.A OD1 no hydrogen 2.836 N/A SER 150.A OG.B ASP 151.A OD1 no hydrogen 2.492 N/A GLY 153.A N HIS 131.A O no hydrogen 2.865 N/A LEU 154.A N ASP 151.A O no hydrogen 3.189 N/A ARG 156.A N GLY 153.A O no hydrogen 3.289 N/A ARG 156.A NE GLY 153.A O no hydrogen 2.895 N/A ARG 156.A NH1 GLU 57.A OE2 no hydrogen 3.210 N/A ARG 156.A NH2 GLU 57.A OE2 no hydrogen 2.886 N/A TYR 157.A N LEU 154.A O no hydrogen 3.065 N/A VAL 158.A N SER 155.A O no hydrogen 3.290 N/A LEU 159.A N SER 48.A O no hydrogen 3.120 N/A GLU 162.A N ASP 160.A OD1 no hydrogen 2.967 N/A TYR 163.A N ASP 160.A O no hydrogen 2.962 N/A THR 164.A N ASP 161.A O no hydrogen 3.215 N/A THR 164.A OG1 ASP 161.A O no hydrogen 3.546 N/A SER 165.A N ASP 161.A O no hydrogen 2.952 N/A GLY 168.A N SER 165.A O no hydrogen 2.795 N/A SER 169.A N GLU 162.A OE1 no hydrogen 2.997 N/A SER 169.A OG GLU 162.A OE1 no hydrogen 2.884 N/A LYS 170.A N GLU 162.A O no hydrogen 2.853 N/A PHE 171.A N GLY 168.A O no hydrogen 3.292 N/A VAL 173.A N PHE 171.A O no hydrogen 2.799 N/A ARG 174.A NE ASN 215.A OD1 no hydrogen 3.032 N/A ARG 174.A NH1 PRO 209.A O no hydrogen 2.987 N/A ARG 174.A NH1 TYR 210.A O no hydrogen 2.890 N/A ARG 174.A NH1 PHE 213.A O no hydrogen 3.111 N/A ARG 174.A NH2 PHE 213.A O no hydrogen 2.797 N/A TRP 175.A N PRO 172.A O no hydrogen 3.018 N/A TRP 175.A NE1 GLU 201.A OE2 no hydrogen 2.891 N/A SER 176.A N VAL 173.A O no hydrogen 3.112 N/A SER 176.A OG PRO 172.A O no hydrogen 2.835 N/A GLU 179.A N GLU 179.A OE1 no hydrogen 2.828 N/A VAL 180.A N PRO 177.A O no hydrogen 3.069 N/A LEU 181.A N PRO 177.A O no hydrogen 3.177 N/A MET 182.A N PRO 178.A O no hydrogen 2.794 N/A TYR 183.A N GLU 179.A O no hydrogen 3.071 N/A SER 184.A N VAL 180.A O no hydrogen 2.936 N/A LYS 185.A N GLU 179.A O no hydrogen 3.053 N/A SER 187.A N SER 190.A OG no hydrogen 2.982 N/A LYS 189.A N SER 187.A OG no hydrogen 2.940 N/A LYS 189.A NZ ARG 253.A O no hydrogen 2.954 N/A LYS 189.A NZ PRO 254.A O no hydrogen 3.065 N/A SER 190.A N SER 187.A O no hydrogen 2.996 N/A SER 190.A OG SER 187.A O no hydrogen 2.897 N/A ASP 191.A N SER 187.A O no hydrogen 3.424 N/A ILE 192.A N SER 188.A O no hydrogen 3.003 N/A TRP 193.A N LYS 189.A O no hydrogen 3.104 N/A ALA 194.A N SER 190.A O no hydrogen 3.109 N/A PHE 195.A N ASP 191.A O no hydrogen 2.855 N/A GLY 196.A N ILE 192.A O no hydrogen 3.080 N/A VAL 197.A N TRP 193.A O no hydrogen 3.100 N/A LEU 198.A N ALA 194.A O no hydrogen 2.811 N/A MET 199.A N PHE 195.A O no hydrogen 2.850 N/A TRP 200.A N GLY 196.A O no hydrogen 3.013 N/A TRP 200.A NE1 TYR 229.A O no hydrogen 2.899 N/A GLU 201.A N VAL 197.A O no hydrogen 2.805 N/A ILE 202.A N LEU 198.A O no hydrogen 2.916 N/A TYR 203.A N MET 199.A O no hydrogen 2.932 N/A SER 204.A N TRP 200.A O no hydrogen 2.887 N/A SER 204.A N GLU 201.A O no hydrogen 3.232 N/A SER 204.A OG TRP 200.A O no hydrogen 2.771 N/A LEU 205.A N ILE 202.A O no hydrogen 3.058 N/A GLY 206.A N GLU 201.A O no hydrogen 2.842 N/A LYS 207.A N SER 204.A O no hydrogen 3.364 N/A ARG 212.A NE.B GLU 211.A O no hydrogen 3.108 N/A ARG 212.A NH2.B GLU 211.A O no hydrogen 3.172 N/A PHE 213.A N TYR 210.A O no hydrogen 2.904 N/A THR 214.A N GLU 217.A OE1 no hydrogen 2.962 N/A GLU 217.A N THR 214.A OG1 no hydrogen 3.052 N/A THR 218.A N THR 214.A O no hydrogen 2.942 N/A THR 218.A OG1 THR 214.A O no hydrogen 2.906 N/A ALA 219.A N ASN 215.A O no hydrogen 2.964 N/A GLU 220.A N SER 216.A O no hydrogen 3.120 N/A HIS 221.A N GLU 217.A O no hydrogen 2.854 N/A ILE 222.A N THR 218.A O no hydrogen 2.916 N/A ALA 223.A N ALA 219.A O no hydrogen 3.033 N/A GLN 224.A N GLU 220.A O no hydrogen 3.031 N/A GLN 224.A NE2 GLU 220.A OE2 no hydrogen 2.656 N/A GLY 225.A N ILE 222.A O no hydrogen 2.989 N/A LEU 226.A N HIS 221.A O no hydrogen 3.126 N/A ARG 227.A NE TRP 246.A O no hydrogen 2.926 N/A ARG 227.A NH1 ILE 222.A O no hydrogen 3.067 N/A ARG 227.A NH1 LEU 226.A O no hydrogen 2.880 N/A ARG 227.A NH2 TRP 246.A O no hydrogen 2.973 N/A ARG 230.A NE ALA 234.A O no hydrogen 2.772 N/A ARG 230.A NH2 ALA 234.A O no hydrogen 3.201 N/A ALA 234.A N PRO 231.A O no hydrogen 2.994 N/A SER 235.A OG GLU 270.A OE1.A no hydrogen 2.764 N/A SER 235.A OG GLU 270.A OE1.B no hydrogen 2.761 N/A SER 235.A OG GLU 270.A OE2.A no hydrogen 3.481 N/A SER 235.A OG GLU 270.A OE2.B no hydrogen 3.536 N/A LYS 237.A NZ GLU 269.A OE1 no hydrogen 2.808 N/A VAL 238.A N SER 235.A OG no hydrogen 3.174 N/A TYR 239.A N SER 235.A O no hydrogen 2.912 N/A THR 240.A N GLU 236.A O no hydrogen 2.927 N/A THR 240.A OG1 GLU 236.A O no hydrogen 2.967 N/A ILE 241.A N LYS 237.A O no hydrogen 3.202 N/A MET 242.A N VAL 238.A O no hydrogen 3.064 N/A TYR 243.A N TYR 239.A O no hydrogen 2.847 N/A SER 244.A N THR 240.A O no hydrogen 3.005 N/A SER 244.A N ILE 241.A O no hydrogen 3.226 N/A SER 244.A OG ILE 241.A O no hydrogen 2.690 N/A CYS 245.A N MET 242.A O no hydrogen 3.086 N/A CYS 245.A SG ILE 241.A O no hydrogen 3.735 N/A TRP 246.A N TYR 243.A O no hydrogen 2.988 N/A HIS 247.A ND1.A SER 244.A O no hydrogen 3.050 N/A GLU 252.A N LYS 249.A O no hydrogen 2.945 N/A ARG 253.A N ALA 250.A O no hydrogen 3.050 N/A ARG 253.A NE HIS 247.A O no hydrogen 2.783 N/A ARG 253.A NH1 GLU 179.A OE2 no hydrogen 2.837 N/A ARG 253.A NH1 LYS 189.A O no hydrogen 3.019 N/A ARG 253.A NH2 GLU 179.A OE1 no hydrogen 2.970 N/A ARG 253.A NH2 HIS 247.A O no hydrogen 2.975 N/A ARG 253.A NH2 GLU 248.A O no hydrogen 3.335 N/A PHE 256.A N GLU 125.A OE1 no hydrogen 2.874 N/A ILE 258.A N THR 255.A OG1 no hydrogen 3.088 N/A LEU 259.A N THR 255.A O no hydrogen 2.952 N/A LEU 260.A N PHE 256.A O no hydrogen 2.876 N/A SER 261.A N LYS 257.A O no hydrogen 3.101 N/A ASN 262.A N ILE 258.A O no hydrogen 2.926 N/A ILE 263.A N LEU 259.A O no hydrogen 2.847 N/A LEU 264.A N LEU 260.A O no hydrogen 2.937 N/A ASP 265.A N SER 261.A O no hydrogen 2.897 N/A VAL 266.A N ASN 262.A O no hydrogen 3.059 N/A MET 267.A N ILE 263.A O no hydrogen 2.931 N/A ASP 268.A N LEU 264.A O no hydrogen 3.008 N/A GLU 269.A N ASP 265.A O no hydrogen 2.982 N/A GLU 269.A N VAL 266.A O no hydrogen 3.024 N/A GLU 270.A N VAL 266.A O no hydrogen 2.784 N/A SER 271.A N MET 267.A O no hydrogen 3.163 N/A