Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4zef_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TYR 4.A N ASN 2.A OD1 no hydrogen 2.953 N/A PHE 5.A N ASN 2.A O no hydrogen 3.130 N/A GLN 6.A NE2 TYR 4.A O no hydrogen 3.040 N/A LYS 9.A N GLU 217.A OE2 no hydrogen 2.813 N/A LYS 14.A N TYR 18.A OH no hydrogen 2.815 N/A LYS 15.A NZ ASP 77.A OD1 no hydrogen 2.681 N/A LYS 17.A NZ GLU 58.A OE1 no hydrogen 3.113 N/A LYS 17.A NZ GLU 58.A OE2 no hydrogen 3.286 N/A TYR 18.A N THR 56.A O no hydrogen 2.893 N/A TYR 18.A OH GLU 210.A OE2 no hydrogen 2.541 N/A VAL 19.A N ASP 77.A OD2 no hydrogen 2.840 N/A ILE 20.A N GLU 58.A O no hydrogen 2.816 N/A ALA 21.A N GLY 78.A O no hydrogen 2.907 N/A SER 22.A N LYS 60.A O.A no hydrogen 2.827 N/A SER 22.A N LYS 60.A O.B no hydrogen 3.036 N/A SER 22.A OG VAL 80.A O no hydrogen 2.713 N/A SER 24.A N.A ASP 23.A OD1 no hydrogen 2.779 N/A THR 25.A OG1.A SER 24.A O.A no hydrogen 2.638 N/A THR 25.A OG1.B ASP 156.A OD1.A no hydrogen 2.917 N/A PHE 26.A N GLU 30.A O no hydrogen 2.717 N/A PHE 29.A N PHE 26.A O no hydrogen 2.808 N/A GLU 30.A N PHE 26.A O no hydrogen 3.079 N/A PHE 31.A N VAL 39.A O no hydrogen 2.943 N/A GLN 32.A NE2 GLY 36.A O no hydrogen 3.050 N/A ASN 33.A N ASP 37.A O no hydrogen 2.894 N/A GLN 35.A N ASN 33.A OD1 no hydrogen 2.972 N/A GLY 36.A N ASN 33.A O no hydrogen 2.879 N/A ASP 37.A N ASN 33.A OD1 no hydrogen 3.010 N/A TYR 38.A OH SER 24.A O.A no hydrogen 2.438 N/A VAL 39.A N PHE 31.A O no hydrogen 2.808 N/A GLY 40.A N TYR 235.A OH no hydrogen 3.118 N/A ILE 41.A N PRO 28.A O no hydrogen 2.871 N/A ASP 42.A N PHE 29.A O no hydrogen 2.886 N/A ASP 44.A N GLY 40.A O no hydrogen 2.834 N/A LEU 45.A N ILE 41.A O no hydrogen 3.000 N/A VAL 46.A N ASP 42.A O no hydrogen 3.070 N/A LYS 47.A N VAL 43.A O no hydrogen 2.901 N/A ARG 48.A N ASP 44.A O no hydrogen 2.888 N/A ARG 48.A NE GLU 227.A OE2 no hydrogen 2.737 N/A ARG 48.A NH1 GLU 51.A OE1.A no hydrogen 2.854 N/A ARG 48.A NH1 GLU 51.A OE1.B no hydrogen 2.859 N/A ARG 48.A NH2 GLU 227.A OE1 no hydrogen 3.013 N/A ARG 48.A NH2 GLU 227.A OE2 no hydrogen 3.568 N/A ALA 49.A N LEU 45.A O no hydrogen 2.920 N/A ALA 50.A N VAL 46.A O no hydrogen 2.989 N/A GLU 51.A N.A LYS 47.A O no hydrogen 2.913 N/A GLU 51.A N.B LYS 47.A O no hydrogen 2.918 N/A LEU 52.A N ARG 48.A O no hydrogen 2.882 N/A GLN 53.A N ALA 50.A O no hydrogen 3.067 N/A GLN 53.A NE2 ALA 49.A O no hydrogen 2.878 N/A GLN 53.A NE2 MET 214.A O.A no hydrogen 2.737 N/A GLN 53.A NE2 MET 214.A O.B no hydrogen 2.852 N/A GLY 54.A N GLU 51.A O.B no hydrogen 3.505 N/A PHE 55.A N ALA 50.A O no hydrogen 2.962 N/A GLU 58.A N TYR 18.A O no hydrogen 2.857 N/A LYS 60.A N.A ILE 20.A O no hydrogen 2.862 N/A LYS 60.A N.B ILE 20.A O no hydrogen 2.896 N/A LYS 60.A NZ.A GLU 58.A OE1 no hydrogen 2.985 N/A ILE 62.A N SER 22.A O no hydrogen 2.929 N/A GLY 63.A N SER 22.A O no hydrogen 3.040 N/A ALA 67.A N GLY 63.A O no hydrogen 2.867 N/A VAL 68.A N PHE 64.A O no hydrogen 2.999 N/A GLN 69.A N SER 65.A O no hydrogen 2.962 N/A ALA 70.A N SER 66.A O no hydrogen 2.927 N/A VAL 71.A N ALA 67.A O no hydrogen 3.026 N/A GLU 72.A N VAL 68.A O no hydrogen 3.009 N/A SER 73.A N.A GLN 69.A O no hydrogen 2.930 N/A SER 73.A N.B GLN 69.A O no hydrogen 2.918 N/A SER 73.A OG.A GLN 69.A O no hydrogen 3.296 N/A SER 73.A OG.A ALA 70.A O no hydrogen 3.151 N/A SER 73.A OG.B GLN 69.A O no hydrogen 2.994 N/A SER 73.A OG.B GLN 69.A OE1 no hydrogen 2.335 N/A GLY 74.A N VAL 71.A O no hydrogen 3.237 N/A GLN 75.A N SER 73.A OG.A no hydrogen 3.339 N/A ALA 76.A N ALA 70.A O no hydrogen 3.024 N/A ASP 77.A N VAL 19.A O no hydrogen 2.782 N/A GLY 78.A N VAL 19.A O no hydrogen 3.226 N/A MET 79.A N ALA 202.A O no hydrogen 2.874 N/A VAL 80.A N ALA 21.A O no hydrogen 3.125 N/A GLY 82.A N ASP 42.A OD2 no hydrogen 2.895 N/A ILE 85.A N SER 198.A O no hydrogen 2.884 N/A ARG 89.A N THR 86.A OG1 no hydrogen 3.155 N/A ARG 89.A NH1 THR 84.A O no hydrogen 2.935 N/A ARG 89.A NH2 GLY 131.A O no hydrogen 3.513 N/A LYS 90.A N THR 86.A O no hydrogen 3.079 N/A LYS 90.A N ASP 87.A O no hydrogen 3.149 N/A LYS 91.A N ASP 88.A O.A no hydrogen 3.196 N/A LYS 91.A N ASP 88.A O.B no hydrogen 3.146 N/A LYS 91.A NZ ASP 88.A OD1.A no hydrogen 2.987 N/A LYS 91.A NZ ASP 88.A OD1.B no hydrogen 3.289 N/A ALA 92.A N ARG 89.A O no hydrogen 2.956 N/A PHE 93.A N ARG 89.A O no hydrogen 2.848 N/A ASP 94.A N VAL 203.A O no hydrogen 2.879 N/A SER 96.A N PHE 201.A O no hydrogen 2.819 N/A SER 96.A OG VAL 97.A O.A no hydrogen 2.799 N/A SER 96.A OG VAL 97.A O.B no hydrogen 2.791 N/A SER 96.A OG PHE 201.A O no hydrogen 3.552 N/A VAL 97.A N.A ASN 216.A OD1 no hydrogen 2.877 N/A VAL 97.A N.B ASN 216.A OD1 no hydrogen 2.918 N/A TYR 99.A N TYR 199.A O no hydrogen 2.987 N/A TYR 99.A OH ASP 42.A OD1 no hydrogen 2.524 N/A SER 102.A N GLY 197.A O no hydrogen 3.131 N/A SER 102.A OG GLY 103.A O no hydrogen 3.444 N/A SER 102.A OG TYR 199.A OH no hydrogen 2.772 N/A ILE 104.A N GLU 194.A O no hydrogen 3.004 N/A GLN 105.A N ASP 172.A O no hydrogen 2.902 N/A GLN 105.A NE2 ILE 191.A O no hydrogen 2.967 N/A ALA 107.A N MET 170.A O no hydrogen 2.877 N/A VAL 108.A N ALA 188.A O no hydrogen 2.912 N/A LYS 110.A N.A PRO 186.A O no hydrogen 2.907 N/A LYS 110.A N.B PRO 186.A O no hydrogen 2.905 N/A ASN 112.A N LYS 109.A O no hydrogen 2.976 N/A ILE 115.A N ASN 112.A OD1 no hydrogen 2.916 N/A LYS 116.A N ASP 120.A OD2 no hydrogen 2.869 N/A TYR 118.A OH GLU 194.A OE2 no hydrogen 2.625 N/A ASP 120.A N SER 117.A O no hydrogen 3.072 N/A LEU 121.A N TYR 118.A O no hydrogen 2.982 N/A LYS 122.A N ASP 119.A O no hydrogen 3.210 N/A LYS 122.A NZ ASP 146.A OD2 no hydrogen 2.826 N/A GLY 123.A N ASP 146.A O no hydrogen 2.838 N/A LYS 124.A N LEU 121.A O no hydrogen 2.858 N/A LYS 125.A N ASP 168.A OD2 no hydrogen 2.803 N/A VAL 126.A N SER 148.A O no hydrogen 2.826 N/A GLY 127.A N ALA 169.A O no hydrogen 2.814 N/A VAL 128.A N LYS 150.A O no hydrogen 2.942 N/A LYS 129.A NZ.A ASP 23.A OD2 no hydrogen 2.773 N/A LYS 129.A NZ.A THR 155.A OG1 no hydrogen 2.831 N/A LYS 129.A NZ.B ASP 23.A OD2 no hydrogen 2.738 N/A LYS 129.A NZ.B THR 155.A OG1 no hydrogen 3.114 N/A ILE 130.A N LEU 152.A O no hydrogen 3.187 N/A THR 132.A OG1 LYS 129.A O.A no hydrogen 2.764 N/A THR 132.A OG1 LYS 129.A O.B no hydrogen 2.864 N/A ALA 135.A N THR 132.A OG1 no hydrogen 3.158 N/A ASP 136.A N THR 132.A O no hydrogen 3.123 N/A PHE 137.A N GLU 133.A O no hydrogen 3.091 N/A LEU 138.A N SER 134.A O no hydrogen 2.969 N/A GLU 139.A N ALA 135.A O no hydrogen 2.911 N/A LYS 140.A N ASP 136.A O no hydrogen 3.028 N/A ASN 141.A N PHE 137.A O no hydrogen 3.145 N/A ASN 141.A N LEU 138.A O no hydrogen 3.287 N/A ASN 141.A ND2 PHE 137.A O no hydrogen 3.104 N/A LYS 142.A N GLU 139.A O no hydrogen 3.400 N/A LYS 142.A NZ GLU 139.A OE1 no hydrogen 3.417 N/A LYS 144.A NZ TYR 145.A OH no hydrogen 3.266 N/A TYR 145.A N ASN 141.A O no hydrogen 3.088 N/A ASP 146.A N LYS 142.A O no hydrogen 2.851 N/A TYR 147.A OH LEU 138.A O no hydrogen 2.714 N/A SER 148.A N LYS 124.A O no hydrogen 2.892 N/A LYS 150.A N VAL 126.A O no hydrogen 2.850 N/A TYR 151.A OH GLU 139.A OE2 no hydrogen 2.557 N/A LEU 152.A N VAL 128.A O no hydrogen 2.842 N/A THR 154.A OG1 ASP 153.A OD1 no hydrogen 3.567 N/A THR 154.A OG1 ASP 156.A OD1.B no hydrogen 2.507 N/A THR 155.A OG1 ASP 172.A OD2 no hydrogen 2.716 N/A ALA 157.A N THR 154.A OG1 no hydrogen 2.982 N/A LEU 158.A N THR 154.A O no hydrogen 3.190 N/A TYR 159.A N THR 155.A O no hydrogen 3.029 N/A SER 160.A N.A ASP 156.A O.A no hydrogen 2.905 N/A SER 160.A N.A ASP 156.A O.B no hydrogen 3.152 N/A SER 160.A N.B ASP 156.A O.A no hydrogen 2.906 N/A SER 160.A N.B ASP 156.A O.B no hydrogen 3.154 N/A SER 160.A OG.B ASP 156.A O.A no hydrogen 3.145 N/A SER 160.A OG.B ASP 156.A O.B no hydrogen 2.869 N/A ALA 161.A N ALA 157.A O no hydrogen 2.899 N/A LEU 162.A N LEU 158.A O no hydrogen 2.924 N/A GLU 163.A N TYR 159.A O no hydrogen 2.946 N/A ILE 164.A N SER 160.A O.A no hydrogen 2.954 N/A ILE 164.A N SER 160.A O.B no hydrogen 2.959 N/A GLY 165.A N LEU 162.A O no hydrogen 3.182 N/A GLU 166.A N ALA 161.A O no hydrogen 2.818 N/A VAL 167.A N ALA 161.A O no hydrogen 3.309 N/A ASP 168.A N LYS 125.A O no hydrogen 2.844 N/A ALA 169.A N LYS 125.A O no hydrogen 3.215 N/A MET 170.A N ALA 107.A O no hydrogen 2.909 N/A MET 171.A N.A GLY 127.A O no hydrogen 3.001 N/A MET 171.A N.B GLY 127.A O no hydrogen 2.979 N/A ASP 172.A N GLN 105.A O no hydrogen 3.205 N/A ASP 173.A N ASP 172.A OD1 no hydrogen 2.720 N/A TYR 174.A N GLY 103.A O no hydrogen 2.872 N/A VAL 176.A N ASP 173.A O no hydrogen 3.121 N/A ILE 177.A N ASP 173.A O no hydrogen 3.129 N/A GLY 178.A N TYR 174.A O no hydrogen 2.838 N/A TYR 179.A N PRO 175.A O no hydrogen 2.974 N/A GLY 180.A N VAL 176.A O no hydrogen 3.115 N/A VAL 181.A N ILE 177.A O no hydrogen 2.850 N/A ALA 182.A N GLY 178.A O no hydrogen 2.930 N/A GLN 183.A N TYR 179.A O no hydrogen 3.203 N/A GLN 183.A N GLY 180.A O no hydrogen 3.156 N/A GLN 183.A NE2 GLN 185.A OE1 no hydrogen 2.816 N/A ASN 184.A N.A VAL 181.A O no hydrogen 2.951 N/A ASN 184.A N.B VAL 181.A O no hydrogen 2.960 N/A GLN 185.A N GLY 180.A O no hydrogen 2.998 N/A LEU 187.A N GLN 185.A O no hydrogen 2.737 N/A ALA 188.A N VAL 108.A O no hydrogen 2.840 N/A GLU 194.A N ILE 104.A O no hydrogen 2.752 N/A GLY 196.A N SER 102.A O no hydrogen 3.105 N/A SER 198.A OG ASP 101.A OD1 no hydrogen 2.936 N/A TYR 199.A N PHE 100.A O no hydrogen 2.828 N/A TYR 199.A OH ASP 173.A OD2 no hydrogen 2.610 N/A GLY 200.A N MET 83.A O no hydrogen 2.921 N/A PHE 201.A N SER 96.A OG no hydrogen 2.924 N/A ALA 202.A N MET 79.A O no hydrogen 3.016 N/A VAL 203.A N ASP 94.A O no hydrogen 3.001 N/A LYS 204.A NZ.A GLU 72.A O no hydrogen 2.873 N/A LYS 204.A NZ.B GLU 72.A O no hydrogen 2.709 N/A LYS 205.A N ALA 92.A O no hydrogen 2.910 N/A GLY 206.A N ASP 94.A OD2 no hydrogen 2.848 N/A GLN 207.A N LYS 204.A O.A no hydrogen 2.933 N/A GLN 207.A N LYS 204.A O.B no hydrogen 2.859 N/A GLU 210.A N GLU 210.A OE1 no hydrogen 2.698 N/A LEU 211.A N ASN 208.A O no hydrogen 3.049 N/A LEU 212.A N ASN 208.A O no hydrogen 3.460 N/A GLU 213.A N PRO 209.A O no hydrogen 2.911 N/A MET 214.A N.A GLU 210.A O no hydrogen 2.889 N/A MET 214.A N.B GLU 210.A O no hydrogen 2.873 N/A PHE 215.A N LEU 211.A O no hydrogen 3.132 N/A ASN 216.A N LEU 212.A O no hydrogen 2.946 N/A GLU 217.A N GLU 213.A O no hydrogen 2.862 N/A GLY 218.A N MET 214.A O.A no hydrogen 2.963 N/A GLY 218.A N MET 214.A O.B no hydrogen 2.855 N/A LEU 219.A N PHE 215.A O no hydrogen 2.836 N/A LYS 220.A N ASN 216.A O no hydrogen 3.011 N/A GLU 221.A N GLU 217.A O no hydrogen 3.071 N/A MET 222.A N GLY 218.A O no hydrogen 2.866 N/A LYS 223.A N LEU 219.A O no hydrogen 2.813 N/A ARG 224.A N LYS 220.A O no hydrogen 2.908 N/A THR 225.A N GLU 221.A O no hydrogen 3.001 N/A THR 225.A OG1 GLU 221.A O no hydrogen 3.342 N/A THR 225.A OG1 MET 222.A O no hydrogen 3.279 N/A GLU 227.A N THR 225.A OG1 no hydrogen 3.077 N/A TYR 228.A N MET 222.A O no hydrogen 2.912 N/A TYR 228.A OH TYR 99.A O no hydrogen 2.580 N/A LYS 230.A N GLY 226.A O no hydrogen 3.010 N/A ILE 231.A N GLU 227.A O no hydrogen 2.859 N/A ILE 232.A N.A TYR 228.A O no hydrogen 3.029 N/A ILE 232.A N.B TYR 228.A O no hydrogen 3.058 N/A GLY 233.A N ASP 229.A O.A no hydrogen 2.961 N/A GLY 233.A N ASP 229.A O.B no hydrogen 2.832 N/A THR 234.A N ILE 231.A O no hydrogen 3.135 N/A THR 234.A OG1 LYS 230.A O no hydrogen 2.793 N/A TYR 235.A N ILE 232.A O.A no hydrogen 3.070 N/A TYR 235.A N ILE 232.A O.B no hydrogen 3.123 N/A TYR 235.A OH ASP 44.A OD1 no hydrogen 3.403 N/A TYR 235.A OH ASP 44.A OD2 no hydrogen 2.562 N/A VAL 236.A N ILE 232.A O.A no hydrogen 2.952 N/A VAL 236.A N ILE 232.A O.B no hydrogen 2.912 N/A LYS 237.A NZ GLY 233.A O no hydrogen 2.726 N/A LYS 237.A NZ THR 234.A O no hydrogen 3.340 N/A