Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4zhx_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 5.A N TYR 8.A O no hydrogen 2.872 N/A TYR 8.A N ILE 5.A O no hydrogen 3.384 N/A TYR 8.A OH HIS 32.A ND1 no hydrogen 2.915 N/A VAL 9.A N GLU 26.A O no hydrogen 2.747 N/A LEU 10.A N VAL 3.A O no hydrogen 3.242 N/A GLY 11.A N ILE 24.A O no hydrogen 2.786 N/A LEU 14.A N VAL 22.A O no hydrogen 2.901 N/A GLY 15.A N VAL 22.A O no hydrogen 3.317 N/A THR 18.A OG1 ASP 149.A OD1 no hydrogen 3.214 N/A LYS 21.A N ILE 38.A O no hydrogen 3.342 N/A VAL 22.A N GLY 15.A O no hydrogen 2.967 N/A LYS 23.A N VAL 36.A O no hydrogen 2.847 N/A LYS 23.A NZ THR 13.A OG1 no hydrogen 2.803 N/A ILE 24.A N ASP 12.A O no hydrogen 3.132 N/A GLY 25.A N VAL 34.A O no hydrogen 2.734 N/A GLU 26.A N VAL 9.A O no hydrogen 2.964 N/A HIS 27.A N HIS 32.A O no hydrogen 2.880 N/A GLN 28.A N HIS 7.A O no hydrogen 3.184 N/A LEU 29.A N HIS 27.A ND1 no hydrogen 3.083 N/A THR 30.A N HIS 27.A ND1 no hydrogen 3.155 N/A HIS 32.A ND1 TYR 8.A OH no hydrogen 2.915 N/A VAL 34.A N GLY 25.A O no hydrogen 2.863 N/A ALA 35.A N MET 85.A O no hydrogen 2.817 N/A VAL 36.A N LYS 23.A O no hydrogen 2.787 N/A LYS 37.A N MET 83.A O no hydrogen 3.034 N/A LYS 37.A NZ GLU 56.A OE2 no hydrogen 2.813 N/A ILE 38.A N LYS 21.A O no hydrogen 2.809 N/A LEU 39.A N PHE 81.A O no hydrogen 2.834 N/A ARG 41.A N THR 79.A O no hydrogen 3.095 N/A ARG 41.A NH1 THR 77.A O no hydrogen 3.538 N/A ARG 41.A NH1 PRO 78.A O no hydrogen 3.447 N/A GLN 42.A N ASN 40.A OD1 no hydrogen 3.223 N/A GLN 42.A NE2 GLN 42.A O no hydrogen 3.654 N/A ILE 44.A N ASN 40.A O no hydrogen 3.140 N/A ARG 45.A N ARG 41.A O no hydrogen 3.280 N/A ARG 45.A NH2 GLN 42.A OE1 no hydrogen 3.228 N/A SER 46.A N GLN 42.A O no hydrogen 3.136 N/A LEU 47.A N ILE 44.A O no hydrogen 3.363 N/A VAL 49.A N ILE 44.A O no hydrogen 3.253 N/A ILE 53.A N VAL 49.A O no hydrogen 2.988 N/A LYS 54.A N VAL 50.A O no hydrogen 3.236 N/A ARG 55.A N GLY 51.A O no hydrogen 3.204 N/A GLU 56.A N LYS 52.A O no hydrogen 3.074 N/A ILE 57.A N ILE 53.A O no hydrogen 3.096 N/A GLN 58.A N LYS 54.A O no hydrogen 3.097 N/A ASN 59.A N ARG 55.A O no hydrogen 3.068 N/A LEU 60.A N GLU 56.A O no hydrogen 3.355 N/A LYS 61.A N ILE 57.A O no hydrogen 3.000 N/A LEU 62.A N ASN 59.A O no hydrogen 3.037 N/A PHE 63.A N ASN 59.A O no hydrogen 2.825 N/A ARG 64.A N TYR 121.A OH no hydrogen 3.099 N/A ARG 64.A NH2 ASP 281.A OD1 no hydrogen 2.795 N/A HIS 67.A N HIS 65.A ND1 no hydrogen 3.022 N/A HIS 67.A ND1 ALA 145.A O no hydrogen 2.956 N/A ILE 68.A N HIS 65.A O no hydrogen 3.429 N/A ILE 69.A N ILE 147.A O no hydrogen 3.082 N/A LYS 70.A NZ GLU 86.A OE1 no hydrogen 2.873 N/A TYR 72.A N VAL 84.A O no hydrogen 3.031 N/A GLN 73.A N VAL 84.A O no hydrogen 3.295 N/A ILE 75.A N PHE 82.A O no hydrogen 2.737 N/A THR 77.A N ASP 80.A O no hydrogen 2.987 N/A THR 77.A OG1 ASP 80.A O no hydrogen 2.613 N/A THR 79.A OG1 ASP 80.A OD1 no hydrogen 3.369 N/A ASP 80.A N THR 77.A OG1 no hydrogen 3.130 N/A PHE 81.A N LEU 39.A O no hydrogen 2.691 N/A PHE 82.A N ILE 75.A O no hydrogen 2.757 N/A MET 83.A N LYS 37.A O no hydrogen 2.891 N/A VAL 84.A N GLN 73.A O no hydrogen 2.860 N/A MET 85.A N ALA 35.A O no hydrogen 2.810 N/A GLU 86.A N LYS 70.A O no hydrogen 2.841 N/A LEU 93.A N VAL 137.A O no hydrogen 2.951 N/A PHE 94.A N PRO 134.A O no hydrogen 2.968 N/A TYR 96.A OH GLU 107.A OE1 no hydrogen 2.705 N/A ILE 97.A N LEU 93.A O no hydrogen 3.050 N/A CYS 98.A N PHE 94.A O no hydrogen 3.090 N/A CYS 98.A SG PHE 94.A O no hydrogen 3.344 N/A LYS 99.A N ASP 95.A O no hydrogen 2.833 N/A HIS 100.A N TYR 96.A O no hydrogen 3.202 N/A VAL 103.A N LEU 198.A O no hydrogen 3.021 N/A GLU 107.A N GLU 104.A O no hydrogen 3.026 N/A ALA 108.A N GLU 104.A O no hydrogen 2.768 N/A ARG 109.A NH1 TRP 258.A O no hydrogen 2.747 N/A ARG 110.A NH1 MET 143.A O no hydrogen 2.754 N/A ARG 110.A NH2 ASN 144.A OD1 no hydrogen 2.962 N/A LEU 111.A N GLU 107.A O no hydrogen 3.100 N/A PHE 112.A N ALA 108.A O no hydrogen 3.060 N/A GLN 113.A N ARG 109.A O no hydrogen 2.832 N/A GLN 113.A NE2 PHE 259.A O no hydrogen 2.900 N/A GLN 113.A NE2 GLN 261.A O no hydrogen 3.024 N/A GLN 114.A N ARG 110.A O no hydrogen 3.259 N/A GLN 114.A NE2 ASN 144.A OD1 no hydrogen 2.766 N/A ILE 115.A N LEU 111.A O no hydrogen 2.984 N/A LEU 116.A N PHE 112.A O no hydrogen 2.954 N/A SER 117.A N GLN 113.A O no hydrogen 3.223 N/A SER 117.A OG HIS 65.A NE2 no hydrogen 3.265 N/A SER 117.A OG LEU 267.A O no hydrogen 2.715 N/A ALA 118.A N GLN 114.A O no hydrogen 3.354 N/A VAL 119.A N ILE 115.A O no hydrogen 2.931 N/A ASP 120.A N LEU 116.A O no hydrogen 2.809 N/A TYR 121.A N SER 117.A O no hydrogen 3.211 N/A CYS 122.A N ALA 118.A O no hydrogen 3.285 N/A CYS 122.A SG ALA 118.A O no hydrogen 3.312 N/A HIS 123.A N VAL 119.A O no hydrogen 3.187 N/A HIS 123.A NE2 ASP 187.A OD2 no hydrogen 2.818 N/A ARG 124.A N ASP 120.A O no hydrogen 2.974 N/A ARG 124.A NE ASP 120.A OD1 no hydrogen 3.383 N/A ARG 124.A NE ASP 120.A OD2 no hydrogen 2.764 N/A HIS 125.A N TYR 121.A O no hydrogen 3.299 N/A HIS 125.A N CYS 122.A O no hydrogen 3.139 N/A HIS 125.A ND1 TYR 121.A O no hydrogen 2.968 N/A MET 126.A N HIS 123.A O no hydrogen 3.240 N/A VAL 127.A N CYS 122.A O no hydrogen 2.798 N/A VAL 128.A N ASN 154.A O no hydrogen 3.092 N/A HIS 129.A N ASP 187.A OD2 no hydrogen 3.255 N/A ARG 130.A N ASP 187.A OD1 no hydrogen 3.100 N/A ARG 130.A NE LEU 152.A O no hydrogen 2.999 N/A ARG 130.A NH1 TYR 181.A OH no hydrogen 3.258 N/A ARG 130.A NH2 LEU 152.A O no hydrogen 3.180 N/A ASN 136.A N LYS 133.A O no hydrogen 2.886 N/A ASN 136.A ND2 ASP 131.A O no hydrogen 2.748 N/A ASN 136.A ND2 ASP 131.A OD2 no hydrogen 2.825 N/A VAL 137.A N LYS 133.A O no hydrogen 3.080 N/A LEU 138.A N LYS 146.A O no hydrogen 2.625 N/A LEU 139.A N GLY 91.A O no hydrogen 2.733 N/A MET 143.A N ASP 140.A O no hydrogen 3.245 N/A ASN 144.A N ASP 140.A OD1 no hydrogen 2.744 N/A ASN 144.A ND2 ASP 140.A OD1 no hydrogen 3.507 N/A ALA 145.A N GLN 114.A OE1 no hydrogen 3.008 N/A LYS 146.A N LEU 138.A O no hydrogen 2.713 N/A LYS 146.A NZ PRO 66.A O no hydrogen 2.995 N/A LYS 146.A NZ GLU 86.A OE1 no hydrogen 3.026 N/A LYS 146.A NZ GLU 86.A OE2 no hydrogen 3.187 N/A ILE 147.A N HIS 67.A O no hydrogen 2.816 N/A ALA 148.A N ASN 136.A O no hydrogen 3.300 N/A SER 153.A OG PHE 150.A O no hydrogen 2.661 N/A ASN 154.A N VAL 128.A O no hydrogen 3.125 N/A MET 156.A N MET 126.A O no hydrogen 2.790 N/A GLU 160.A N SER 157.A O no hydrogen 3.443 N/A LEU 162.A N TYR 181.A O no hydrogen 2.830 N/A SER 164.A OG VAL 175.A O no hydrogen 3.141 N/A CYS 165.A SG LEU 152.A O no hydrogen 3.831 N/A ASN 169.A ND2 PHE 205.A O no hydrogen 3.082 N/A TYR 170.A N SER 167.A O no hydrogen 3.211 N/A ALA 171.A N SER 167.A O no hydrogen 2.981 N/A GLU 174.A N GLU 174.A OE1 no hydrogen 2.794 N/A VAL 175.A N ALA 172.A O no hydrogen 3.003 N/A ILE 176.A N ALA 172.A O no hydrogen 3.271 N/A SER 177.A N PRO 173.A O no hydrogen 3.323 N/A SER 177.A OG PRO 173.A O no hydrogen 2.705 N/A GLY 178.A N VAL 175.A O no hydrogen 3.244 N/A ARG 179.A N GLU 174.A O no hydrogen 3.174 N/A TYR 181.A N LEU 162.A O no hydrogen 2.929 N/A ALA 182.A N GLU 185.A OE2 no hydrogen 2.824 N/A GLY 183.A N GLU 185.A OE1 no hydrogen 3.019 N/A GLY 183.A N GLU 185.A OE2 no hydrogen 3.460 N/A GLU 185.A N GLU 185.A OE1 no hydrogen 2.738 N/A VAL 186.A N GLY 183.A O no hydrogen 3.182 N/A ILE 188.A N PRO 184.A O no hydrogen 3.247 N/A TRP 189.A N GLU 185.A O no hydrogen 3.321 N/A SER 190.A N VAL 186.A O no hydrogen 3.120 N/A SER 190.A OG TYR 170.A O no hydrogen 3.076 N/A SER 190.A OG VAL 186.A O no hydrogen 3.306 N/A CYS 191.A N ASP 187.A O no hydrogen 2.860 N/A CYS 191.A SG ASP 187.A O no hydrogen 3.352 N/A GLY 192.A N ILE 188.A O no hydrogen 2.909 N/A VAL 193.A N TRP 189.A O no hydrogen 3.176 N/A ILE 194.A N SER 190.A O no hydrogen 3.239 N/A LEU 195.A N CYS 191.A O no hydrogen 3.024 N/A TYR 196.A N GLY 192.A O no hydrogen 3.210 N/A TYR 196.A OH TYR 223.A O no hydrogen 2.643 N/A ALA 197.A N VAL 193.A O no hydrogen 2.881 N/A LEU 198.A N ILE 194.A O no hydrogen 2.932 N/A LEU 199.A N LEU 195.A O no hydrogen 3.337 N/A CYS 200.A N TYR 196.A O no hydrogen 2.812 N/A GLY 201.A N ALA 197.A O no hydrogen 3.162 N/A HIS 209.A N ASP 207.A OD1 no hydrogen 2.843 N/A HIS 209.A ND1 THR 212.A OG1 no hydrogen 2.795 N/A THR 212.A OG1 HIS 209.A ND1 no hydrogen 2.795 N/A LEU 213.A N HIS 209.A O no hydrogen 3.092 N/A PHE 214.A N VAL 210.A O no hydrogen 3.089 N/A LYS 215.A N PRO 211.A O no hydrogen 3.113 N/A LYS 216.A N THR 212.A O no hydrogen 3.359 N/A LYS 216.A N LEU 213.A O no hydrogen 3.207 N/A LYS 216.A NZ ASP 206.A O no hydrogen 2.890 N/A LYS 216.A NZ ASP 207.A OD2 no hydrogen 3.073 N/A ILE 217.A N LEU 213.A O no hydrogen 3.344 N/A ARG 218.A N PHE 214.A O no hydrogen 3.207 N/A GLY 219.A N LYS 215.A O no hydrogen 3.080 N/A GLY 220.A N LYS 216.A O no hydrogen 2.902 N/A TYR 227.A OH CYS 200.A O no hydrogen 3.366 N/A LEU 228.A N PRO 225.A O no hydrogen 3.391 N/A ALA 233.A N ASN 229.A O no hydrogen 3.175 N/A THR 234.A N ARG 230.A O no hydrogen 3.374 N/A THR 234.A OG1 ARG 230.A O no hydrogen 3.437 N/A THR 234.A OG1 SER 231.A O no hydrogen 2.819 N/A LEU 236.A N VAL 232.A O no hydrogen 3.098 N/A MET 237.A N ALA 233.A O no hydrogen 3.201 N/A HIS 238.A N THR 234.A O no hydrogen 3.125 N/A MET 239.A N LEU 235.A O no hydrogen 3.058 N/A LEU 240.A N LEU 236.A O no hydrogen 2.906 N/A GLN 241.A NE2 MET 237.A O no hydrogen 2.989 N/A LEU 245.A N ASP 243.A OD1 no hydrogen 3.294 N/A ARG 247.A N ASP 243.A O no hydrogen 3.062 N/A ARG 247.A NE GLN 241.A O no hydrogen 2.809 N/A ARG 247.A NH1 GLU 174.A OE1 no hydrogen 3.537 N/A ARG 247.A NH1 GLU 185.A O no hydrogen 2.828 N/A ARG 247.A NH2 GLU 174.A OE1 no hydrogen 2.785 N/A ARG 247.A NH2 GLN 241.A O no hydrogen 3.149 N/A ARG 247.A NH2 VAL 242.A O no hydrogen 3.155 N/A ALA 248.A N HIS 238.A O no hydrogen 3.022 N/A THR 249.A OG1 ASP 252.A OD2 no hydrogen 2.704 N/A ILE 253.A N THR 249.A O no hydrogen 3.000 N/A ARG 254.A N ILE 250.A O no hydrogen 2.963 N/A HIS 256.A N ILE 253.A O no hydrogen 3.144 N/A HIS 256.A NE2 SER 231.A O no hydrogen 2.752 N/A LYS 260.A N HIS 256.A O no hydrogen 3.174 N/A LYS 260.A NZ GLU 255.A O no hydrogen 3.513 N/A LYS 260.A NZ GLU 257.A OE2 no hydrogen 3.565 N/A LEU 263.A N LYS 260.A O no hydrogen 3.321 N/A ASP 271.A N PHE 268.A O no hydrogen 3.324 N/A ASN 277.A N SER 273.A O no hydrogen 3.025 N/A ASN 277.A ND2 SER 273.A O no hydrogen 2.809 N/A VAL 278.A N TYR 274.A O no hydrogen 2.819 N/A ASP 280.A N TYR 293.A OH no hydrogen 3.241 N/A GLU 286.A N GLU 282.A O no hydrogen 2.834 N/A LEU 295.A N VAL 291.A O no hydrogen 3.364 N/A ILE 297.A N TYR 293.A O no hydrogen 3.428 N/A ASP 298.A N HIS 294.A O no hydrogen 3.193 N/A ASN 299.A N LEU 295.A O no hydrogen 3.131 N/A ARG 300.A N ILE 296.A O no hydrogen 3.002 N/A ARG 301.A N ILE 297.A O no hydrogen 3.123 N/A ARG 301.A NH1 ASP 298.A OD1 no hydrogen 2.842 N/A ARG 301.A NH2 ASP 298.A OD1 no hydrogen 3.086 N/A ILE 302.A N ASP 298.A O no hydrogen 3.326 N/A MET 303.A N ASN 299.A O no hydrogen 3.347 N/A ASN 304.A N ARG 300.A O no hydrogen 2.922 N/A GLN 305.A N ARG 301.A O no hydrogen 3.017 N/A ALA 306.A N ILE 302.A O no hydrogen 3.437 N/A SER 307.A N GLN 305.A O no hydrogen 3.076 N/A LEU 311.A N SER 307.A O no hydrogen 2.875 N/A LYS 316.A NZ TRP 317.A O no hydrogen 3.505 N/A HIS 318.A ND1 GLY 320.A O no hydrogen 3.080 N/A SER 323.A N TYR 380.A O no hydrogen 2.984 N/A SER 323.A OG SER 325.A OG no hydrogen 2.879 N/A SER 325.A OG SER 323.A OG no hydrogen 2.879 N/A ILE 330.A N LYS 326.A O no hydrogen 3.243 N/A MET 331.A N PRO 327.A O no hydrogen 3.185 N/A ALA 332.A N TYR 328.A O no hydrogen 3.065 N/A GLU 333.A N ASP 329.A O no hydrogen 3.107 N/A VAL 334.A N ILE 330.A O no hydrogen 3.096 N/A TYR 335.A N MET 331.A O no hydrogen 3.368 N/A ALA 337.A N GLU 333.A O no hydrogen 3.353 N/A LYS 339.A NZ TYR 335.A O no hydrogen 3.506 N/A GLN 340.A NE2 ARG 336.A O no hydrogen 3.347 N/A ASP 342.A N LYS 339.A O no hydrogen 3.448 N/A PHE 343.A N MET 338.A O no hydrogen 3.152 N/A GLU 344.A N ARG 356.A O no hydrogen 2.961 N/A LYS 346.A N ARG 354.A O no hydrogen 2.740 N/A VAL 348.A N HIS 352.A O no hydrogen 3.409 N/A ASN 349.A N HIS 352.A O no hydrogen 3.166 N/A HIS 352.A ND1 GLN 371.A OE1 no hydrogen 2.796 N/A LEU 353.A N LEU 370.A O no hydrogen 2.829 N/A ARG 354.A N LYS 346.A O no hydrogen 2.883 N/A VAL 355.A N MET 368.A O no hydrogen 2.940 N/A ARG 356.A N GLU 344.A O no hydrogen 2.815 N/A ARG 357.A N VAL 366.A O no hydrogen 2.823 N/A ASN 359.A N ASN 364.A O no hydrogen 3.203 N/A VAL 361.A N ASN 359.A OD1 no hydrogen 3.151 N/A THR 362.A N ASN 359.A OD1 no hydrogen 2.944 N/A GLY 363.A N ASN 359.A O no hydrogen 3.204 N/A VAL 366.A N ARG 357.A O no hydrogen 2.758 N/A MET 368.A N VAL 355.A O no hydrogen 3.075 N/A SER 369.A N LYS 385.A O no hydrogen 2.654 N/A LEU 370.A N LEU 353.A O no hydrogen 2.789 N/A GLN 371.A N ASP 383.A O no hydrogen 3.235 N/A GLN 371.A NE2 LEU 372.A O no hydrogen 3.648 N/A LEU 372.A N TYR 351.A O no hydrogen 3.304 N/A TYR 373.A N LEU 381.A O no hydrogen 2.768 N/A VAL 375.A N SER 379.A O no hydrogen 2.919 N/A SER 379.A OG VAL 375.A O no hydrogen 3.309 N/A SER 379.A OG ASN 377.A O no hydrogen 3.519 N/A TYR 380.A N SER 323.A O no hydrogen 2.811 N/A LEU 381.A N TYR 373.A O no hydrogen 3.044 N/A LEU 382.A N ILE 321.A O no hydrogen 3.052 N/A ASP 383.A N GLN 371.A O no hydrogen 2.799 N/A LYS 385.A N SER 369.A O no hydrogen 3.032 N/A LYS 385.A NZ SER 386.A O no hydrogen 3.562 N/A ILE 387.A N LYS 367.A O no hydrogen 3.195 N/A ASP 396.A N SER 392.A O no hydrogen 3.015 N/A PHE 397.A N HIS 393.A O no hydrogen 3.241 N/A PHE 398.A N THR 394.A O no hydrogen 3.153 N/A GLU 399.A N MET 395.A O no hydrogen 3.094 N/A MET 400.A N ASP 396.A O no hydrogen 3.244 N/A CYS 401.A N PHE 397.A O no hydrogen 3.179 N/A CYS 401.A SG PHE 397.A O no hydrogen 3.326 N/A ALA 402.A N PHE 398.A O no hydrogen 2.989 N/A SER 403.A N GLU 399.A O no hydrogen 3.197 N/A SER 403.A OG GLU 399.A O no hydrogen 2.605 N/A SER 403.A OG MET 400.A O no hydrogen 3.418 N/A ILE 405.A N CYS 401.A O no hydrogen 2.947 N/A THR 406.A N ALA 402.A O no hydrogen 3.305 N/A THR 406.A OG1 ALA 402.A O no hydrogen 2.738 N/A THR 406.A OG1 SER 403.A O no hydrogen 3.041 N/A THR 407.A N SER 403.A O no hydrogen 3.251 N/A THR 407.A OG1 SER 403.A O no hydrogen 2.610 N/A LEU 408.A N LEU 404.A O no hydrogen 3.021 N/A