Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 4zy4_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 6.A N GLU 3.A O no hydrogen 3.248 N/A ARG 10.A NH2 GLU 7.A OE1 no hydrogen 3.490 N/A SER 11.A N LYS 8.A O no hydrogen 3.215 N/A SER 11.A OG LYS 8.A O no hydrogen 2.428 N/A VAL 13.A N LEU 9.A O no hydrogen 3.509 N/A SER 14.A N SER 80.A O no hydrogen 2.899 N/A SER 14.A OG SER 80.A O no hydrogen 2.927 N/A LYS 19.A N ASP 17.A OD1 no hydrogen 2.892 N/A LYS 20.A N ASP 17.A O no hydrogen 3.292 N/A LYS 21.A N PRO 18.A O no hydrogen 3.125 N/A LYS 21.A NZ ASP 79.A OD2 no hydrogen 3.468 N/A TYR 22.A N PRO 18.A O no hydrogen 3.357 N/A GLU 26.A N THR 38.A O no hydrogen 2.908 N/A LYS 27.A NZ TYR 37.A OH no hydrogen 3.362 N/A ILE 28.A N VAL 36.A O no hydrogen 3.123 N/A GLY 31.A N GLY 34.A O no hydrogen 3.428 N/A THR 35.A OG1 GLY 29.A O no hydrogen 2.665 N/A VAL 36.A N GLY 29.A O no hydrogen 3.280 N/A TYR 37.A N ILE 50.A O no hydrogen 2.706 N/A THR 38.A OG1 GLU 26.A O no hydrogen 3.146 N/A ALA 39.A N VAL 48.A O no hydrogen 2.897 N/A MET 40.A N THR 23.A O no hydrogen 3.152 N/A ASP 41.A N GLN 46.A O no hydrogen 2.527 N/A VAL 42.A N LYS 21.A O no hydrogen 3.124 N/A ALA 43.A N ASP 41.A OD2 no hydrogen 2.989 N/A GLY 45.A N ASP 41.A O no hydrogen 2.785 N/A VAL 48.A N ALA 39.A O no hydrogen 2.612 N/A ALA 49.A N MET 91.A O no hydrogen 2.862 N/A ILE 50.A N TYR 37.A O no hydrogen 3.490 N/A LYS 51.A N VAL 89.A O no hydrogen 2.868 N/A LYS 51.A NZ GLU 62.A OE1 no hydrogen 3.233 N/A GLN 52.A N THR 35.A O no hydrogen 2.782 N/A GLN 53.A NE2 ASP 85.A O no hydrogen 3.383 N/A LEU 58.A N LYS 55.A O no hydrogen 3.386 N/A ILE 60.A N LYS 56.A O no hydrogen 3.295 N/A ASN 61.A N GLU 57.A O no hydrogen 3.195 N/A GLU 62.A N LEU 58.A O no hydrogen 2.768 N/A ILE 63.A N ILE 59.A O no hydrogen 3.026 N/A LEU 64.A N ILE 60.A O no hydrogen 2.953 N/A VAL 65.A N ASN 61.A O no hydrogen 3.085 N/A MET 66.A N GLU 62.A O no hydrogen 3.164 N/A ARG 67.A N ILE 63.A O no hydrogen 2.942 N/A GLU 68.A N LEU 64.A O no hydrogen 3.205 N/A ASN 69.A N MET 66.A O no hydrogen 3.411 N/A ASN 69.A ND2 VAL 65.A O no hydrogen 2.493 N/A ASN 73.A N ASN 71.A OD1 no hydrogen 3.084 N/A ASN 73.A ND2 GLU 119.A OE1 no hydrogen 2.981 N/A ASN 73.A ND2 VAL 150.A O no hydrogen 2.774 N/A ILE 74.A N ASN 71.A O no hydrogen 3.036 N/A VAL 75.A N LEU 152.A O no hydrogen 2.831 N/A ASN 76.A N GLU 92.A OE1 no hydrogen 3.024 N/A LEU 78.A N VAL 90.A O no hydrogen 2.740 N/A TYR 81.A N TRP 88.A O no hydrogen 3.013 N/A TRP 88.A N TYR 81.A O no hydrogen 2.832 N/A VAL 89.A N LYS 51.A O no hydrogen 3.268 N/A VAL 90.A N ASP 79.A O no hydrogen 2.843 N/A MET 91.A N ALA 49.A O no hydrogen 2.845 N/A GLU 92.A N ASN 76.A O no hydrogen 2.852 N/A LEU 99.A N ILE 142.A O no hydrogen 2.853 N/A THR 100.A OG1 SER 139.A OG no hydrogen 2.886 N/A VAL 103.A N LEU 99.A O no hydrogen 2.961 N/A THR 104.A N THR 100.A O no hydrogen 3.121 N/A THR 104.A OG1 THR 100.A O no hydrogen 3.197 N/A GLU 105.A N VAL 102.A O no hydrogen 3.385 N/A THR 106.A N VAL 102.A O no hydrogen 2.840 N/A THR 106.A OG1 VAL 102.A O no hydrogen 2.636 N/A ASP 109.A N GLN 112.A OE1 no hydrogen 2.958 N/A GLN 112.A N ASP 109.A O no hydrogen 3.033 N/A GLN 112.A N ASP 109.A OD1 no hydrogen 2.894 N/A GLN 112.A NE2 SER 276.A O no hydrogen 2.994 N/A ILE 113.A N ASP 109.A O no hydrogen 3.049 N/A ALA 114.A N GLU 110.A O no hydrogen 2.861 N/A ALA 115.A N GLY 111.A O no hydrogen 3.339 N/A VAL 116.A N GLN 112.A O no hydrogen 3.168 N/A CYS 117.A N ILE 113.A O no hydrogen 2.955 N/A CYS 117.A SG ILE 113.A O no hydrogen 3.201 N/A ARG 118.A N ALA 114.A O no hydrogen 2.894 N/A GLU 119.A N ALA 115.A O no hydrogen 3.227 N/A CYS 120.A N VAL 116.A O no hydrogen 2.970 N/A CYS 120.A SG VAL 116.A O no hydrogen 3.448 N/A LEU 121.A N CYS 117.A O no hydrogen 2.793 N/A GLN 122.A N ARG 118.A O no hydrogen 3.040 N/A GLN 122.A NE2 ASN 73.A OD1 no hydrogen 2.741 N/A GLN 122.A NE2 GLU 119.A OE1 no hydrogen 3.558 N/A ALA 123.A N GLU 119.A O no hydrogen 3.201 N/A LEU 124.A N CYS 120.A O no hydrogen 2.857 N/A GLU 125.A N LEU 121.A O no hydrogen 2.709 N/A PHE 126.A N GLN 122.A O no hydrogen 3.085 N/A LEU 127.A N ALA 123.A O no hydrogen 2.951 N/A HIS 128.A N LEU 124.A O no hydrogen 2.861 N/A HIS 128.A NE2 ASP 193.A OD2 no hydrogen 3.031 N/A SER 129.A N GLU 125.A O no hydrogen 3.080 N/A SER 129.A OG GLU 125.A O no hydrogen 3.321 N/A SER 129.A OG PHE 126.A O no hydrogen 2.715 N/A ASN 130.A N PHE 126.A O no hydrogen 3.165 N/A ASN 130.A N LEU 127.A O no hydrogen 2.965 N/A ASN 130.A ND2 ASN 69.A OD1 no hydrogen 3.394 N/A GLN 131.A N HIS 128.A O no hydrogen 2.775 N/A VAL 132.A N LEU 127.A O no hydrogen 3.010 N/A ILE 133.A N ALA 159.A O no hydrogen 2.915 N/A HIS 134.A N ASP 193.A OD2 no hydrogen 2.846 N/A HIS 134.A NE2 THR 153.A O no hydrogen 2.759 N/A ARG 135.A N ASP 193.A OD1 no hydrogen 2.822 N/A ARG 135.A NE PHE 157.A O no hydrogen 2.660 N/A ARG 135.A NH1 THR 170.A OG1 no hydrogen 3.226 N/A ARG 135.A NH1 TYR 188.A OH no hydrogen 3.131 N/A ARG 135.A NH2 PHE 157.A O no hydrogen 2.956 N/A ARG 135.A NH2 CYS 158.A O no hydrogen 3.396 N/A ASN 136.A N HIS 134.A ND1 no hydrogen 3.039 N/A LYS 138.A NZ THR 174.A OG1 no hydrogen 3.017 N/A SER 139.A N GLU 203.A OE1 no hydrogen 3.182 N/A SER 139.A OG THR 100.A OG1 no hydrogen 2.886 N/A SER 139.A OG GLU 203.A OE1 no hydrogen 3.382 N/A SER 139.A OG GLU 203.A OE2 no hydrogen 2.573 N/A ASN 141.A N LYS 138.A O no hydrogen 2.850 N/A ASN 141.A ND2 ASN 136.A O no hydrogen 2.806 N/A ILE 142.A N SER 139.A O no hydrogen 3.218 N/A LEU 143.A N LYS 151.A O no hydrogen 2.938 N/A LEU 144.A N GLY 97.A O no hydrogen 2.691 N/A GLY 145.A N SER 149.A O no hydrogen 2.744 N/A ASP 147.A N ASP 147.A OD1 no hydrogen 2.520 N/A GLY 148.A N GLY 145.A O no hydrogen 2.793 N/A SER 149.A OG ASP 147.A OD1 no hydrogen 2.886 N/A SER 149.A OG ASP 147.A OD2 no hydrogen 3.078 N/A LYS 151.A N LEU 143.A O no hydrogen 3.023 N/A LYS 151.A NZ PRO 72.A O no hydrogen 2.924 N/A LYS 151.A NZ GLU 92.A OE1 no hydrogen 3.291 N/A LEU 152.A N ASN 73.A O no hydrogen 2.866 N/A THR 153.A N ASN 141.A O no hydrogen 3.064 N/A ASP 154.A N THR 153.A OG1 no hydrogen 2.605 N/A PHE 155.A N GLU 62.A OE1 no hydrogen 3.493 N/A CYS 158.A N PHE 155.A O no hydrogen 3.205 N/A CYS 158.A SG ILE 133.A O no hydrogen 3.975 N/A ALA 159.A N ILE 133.A O no hydrogen 2.770 N/A ILE 161.A N GLN 131.A O no hydrogen 3.008 N/A THR 162.A N GLN 165.A O no hydrogen 3.208 N/A ARG 168.A N TYR 188.A O no hydrogen 3.257 N/A ARG 168.A NH2 GLN 160.A O no hydrogen 2.863 N/A THR 170.A OG1 TYR 188.A OH no hydrogen 3.306 N/A THR 174.A OG1 ASN 136.A OD1 no hydrogen 3.014 N/A TYR 176.A OH GLU 214.A O no hydrogen 2.972 N/A TRP 177.A N THR 174.A O no hydrogen 2.860 N/A TRP 177.A NE1 GLU 203.A OE1 no hydrogen 2.812 N/A MET 178.A N PRO 175.A O no hydrogen 2.873 N/A GLU 181.A N GLU 181.A OE2 no hydrogen 2.836 N/A VAL 182.A N ALA 179.A O no hydrogen 2.833 N/A VAL 183.A N ALA 179.A O no hydrogen 3.043 N/A THR 184.A N PRO 180.A O no hydrogen 2.934 N/A THR 184.A OG1 PRO 180.A O no hydrogen 3.015 N/A LYS 186.A N GLU 181.A O no hydrogen 3.083 N/A TYR 188.A N ARG 168.A O no hydrogen 2.982 N/A TYR 188.A OH THR 170.A O no hydrogen 2.777 N/A TYR 188.A OH THR 170.A OG1 no hydrogen 3.306 N/A LYS 191.A NZ VAL 253.A O no hydrogen 2.958 N/A LYS 191.A NZ ARG 256.A O no hydrogen 2.753 N/A VAL 192.A N GLY 189.A O no hydrogen 3.127 N/A ASP 193.A N PRO 190.A O no hydrogen 2.956 N/A TRP 195.A N LYS 191.A O no hydrogen 3.164 N/A SER 196.A N VAL 192.A O no hydrogen 3.061 N/A SER 196.A OG TRP 177.A O no hydrogen 2.940 N/A SER 196.A OG VAL 192.A O no hydrogen 3.064 N/A LEU 197.A N ASP 193.A O no hydrogen 2.909 N/A GLY 198.A N ILE 194.A O no hydrogen 3.056 N/A ILE 199.A N TRP 195.A O no hydrogen 3.018 N/A MET 200.A N SER 196.A O no hydrogen 2.930 N/A ALA 201.A N LEU 197.A O no hydrogen 2.861 N/A ALA 201.A N GLY 198.A O no hydrogen 2.852 N/A ILE 202.A N GLY 198.A O no hydrogen 3.048 N/A GLU 203.A N ILE 199.A O no hydrogen 2.993 N/A MET 204.A N MET 200.A O no hydrogen 3.038 N/A ILE 205.A N ALA 201.A O no hydrogen 2.950 N/A ILE 205.A N ILE 202.A O no hydrogen 3.149 N/A GLU 206.A N ILE 202.A O no hydrogen 2.735 N/A GLY 207.A N GLU 203.A O no hydrogen 2.816 N/A GLU 214.A N TYR 211.A O no hydrogen 2.936 N/A LEU 217.A N ASN 215.A OD1 no hydrogen 2.737 N/A ALA 219.A N ASN 215.A O no hydrogen 2.773 N/A LEU 220.A N PRO 216.A O no hydrogen 2.888 N/A TYR 221.A N LEU 217.A O no hydrogen 2.890 N/A LEU 222.A N ARG 218.A O no hydrogen 2.872 N/A ILE 223.A N ALA 219.A O no hydrogen 2.858 N/A ALA 224.A N LEU 220.A O no hydrogen 3.202 N/A THR 225.A N TYR 221.A O no hydrogen 2.972 N/A THR 225.A N LEU 222.A O no hydrogen 3.238 N/A THR 225.A OG1 TYR 221.A O no hydrogen 3.178 N/A THR 225.A OG1 LEU 222.A O no hydrogen 3.233 N/A THR 225.A OG1 ASN 226.A OD1 no hydrogen 3.556 N/A ASN 226.A N LEU 222.A O no hydrogen 2.738 N/A ASN 226.A ND2 TYR 211.A OH no hydrogen 3.043 N/A GLY 227.A N ILE 223.A O no hydrogen 3.263 N/A GLN 232.A N GLU 206.A OE2 no hydrogen 2.928 N/A ASN 233.A ND2 GLU 235.A OE2 no hydrogen 2.880 N/A LYS 236.A N ASN 233.A O no hydrogen 3.028 N/A LEU 237.A N PRO 234.A O no hydrogen 3.239 N/A SER 238.A N GLU 110.A OE2 no hydrogen 2.820 N/A SER 238.A OG GLU 110.A OE1 no hydrogen 2.744 N/A SER 238.A OG GLU 110.A OE2 no hydrogen 3.516 N/A PHE 241.A N SER 238.A OG no hydrogen 3.041 N/A ARG 242.A N SER 238.A O no hydrogen 3.197 N/A ASP 243.A N ALA 239.A O no hydrogen 3.051 N/A PHE 244.A N ILE 240.A O no hydrogen 3.164 N/A LEU 245.A N PHE 241.A O no hydrogen 2.940 N/A ASN 246.A N ARG 242.A O no hydrogen 2.958 N/A ARG 247.A N ASP 243.A O no hydrogen 2.986 N/A CYS 248.A N PHE 244.A O no hydrogen 3.065 N/A CYS 248.A N LEU 245.A O no hydrogen 3.104 N/A CYS 248.A SG PHE 244.A O no hydrogen 3.380 N/A LEU 249.A N LEU 245.A O no hydrogen 2.913 N/A ASP 252.A N GLU 250.A OE2 no hydrogen 3.516 N/A LYS 255.A N ASP 252.A O no hydrogen 2.775 N/A LYS 255.A N ASP 252.A OD2 no hydrogen 3.338 N/A ARG 256.A N VAL 253.A O no hydrogen 3.155 N/A ARG 256.A NE GLU 250.A O no hydrogen 2.778 N/A ARG 256.A NH1 GLU 181.A OE1 no hydrogen 2.737 N/A ARG 256.A NH1 LYS 191.A O no hydrogen 3.002 N/A ARG 256.A NH2 GLU 181.A OE1 no hydrogen 3.522 N/A ARG 256.A NH2 GLU 181.A OE2 no hydrogen 3.039 N/A ARG 256.A NH2 GLU 250.A O no hydrogen 2.882 N/A GLY 257.A N ARG 247.A O no hydrogen 2.898 N/A SER 258.A N GLU 261.A OE1 no hydrogen 2.841 N/A GLU 261.A N SER 258.A OG no hydrogen 3.039 N/A LEU 262.A N SER 258.A O no hydrogen 2.771 N/A LEU 263.A N ALA 259.A O no hydrogen 2.856 N/A GLN 264.A N GLU 261.A O no hydrogen 3.029 N/A HIS 265.A N LEU 262.A O no hydrogen 3.098 N/A HIS 265.A NE2 ASP 243.A OD1 no hydrogen 2.689 N/A PHE 267.A N HIS 265.A ND1 no hydrogen 3.013 N/A LEU 268.A N HIS 265.A O no hydrogen 3.127 N/A LYS 269.A N GLN 266.A O no hydrogen 3.186 N/A ILE 270.A N PHE 267.A O no hydrogen 3.290 N/A ALA 271.A N LEU 268.A O no hydrogen 3.153 N/A LYS 272.A N GLY 111.A O no hydrogen 2.868 N/A LYS 272.A NZ ASP 109.A OD2 no hydrogen 2.972 N/A SER 276.A N PRO 273.A O no hydrogen 2.900 N/A SER 276.A OG PRO 273.A O no hydrogen 2.598 N/A LEU 277.A N LEU 274.A O no hydrogen 3.170 N/A THR 278.A N SER 275.A O no hydrogen 3.170 N/A THR 278.A OG1 SER 275.A O no hydrogen 2.665 N/A ILE 281.A N LEU 277.A O no hydrogen 2.971 N/A ALA 282.A N THR 278.A O no hydrogen 2.936 N/A ALA 283.A N PRO 279.A O no hydrogen 2.911 N/A ALA 284.A N LEU 280.A O no hydrogen 2.972 N/A LYS 285.A N ILE 281.A O no hydrogen 2.866 N/A LYS 285.A NZ ALA 95.A O no hydrogen 3.316 N/A LYS 285.A NZ GLY 96.A O no hydrogen 3.544 N/A GLU 286.A N ALA 282.A O no hydrogen 3.063 N/A THR 288.A OG1 ALA 284.A O no hydrogen 3.165 N/A THR 288.A OG1 ALA 287.A O no hydrogen 2.702 N/A