Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5a4t_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 4.A ND2 ASP 8.A OD1 no hydrogen 3.409 N/A ASN 4.A ND2 ARG 98.A O no hydrogen 3.014 N/A GLY 6.A N TYR 3.A O no hydrogen 2.973 N/A TYR 7.A N ASN 4.A O no hydrogen 3.160 N/A ASP 8.A N TYR 3.A O no hydrogen 3.167 N/A ASP 9.A N ASP 13.A O no hydrogen 3.194 N/A TYR 12.A N ASP 9.A O no hydrogen 3.437 N/A ASP 13.A N ASP 9.A OD1 no hydrogen 2.992 N/A TYR 14.A OH GLU 20.A OE1 no hydrogen 3.094 N/A ILE 15.A N TYR 7.A O no hydrogen 2.889 N/A LYS 17.A NZ ILE 15.A O no hydrogen 3.507 N/A ASN 18.A ND2 ASP 29.A O no hydrogen 2.571 N/A GLY 19.A N ILE 28.A O no hydrogen 2.950 N/A GLU 20.A N LYS 17.A O no hydrogen 3.406 N/A LYS 21.A NZ GLU 27.A OE2 no hydrogen 3.361 N/A TRP 22.A N TYR 26.A O no hydrogen 2.818 N/A ARG 25.A N TRP 22.A O no hydrogen 2.960 N/A ARG 25.A NE ASP 45.A OD1 no hydrogen 2.754 N/A ARG 25.A NE ASP 45.A OD2 no hydrogen 3.432 N/A ARG 25.A NH2 ASP 45.A OD2 no hydrogen 2.958 N/A TYR 26.A N TRP 22.A O no hydrogen 3.146 N/A GLU 27.A N TYR 44.A O no hydrogen 2.984 N/A ILE 28.A N GLU 20.A O no hydrogen 2.823 N/A ASP 29.A N LYS 42.A O no hydrogen 2.762 N/A SER 30.A OG ASP 29.A OD2 no hydrogen 3.086 N/A ILE 32.A N VAL 40.A O no hydrogen 2.847 N/A GLY 35.A N GLY 38.A O no hydrogen 2.937 N/A GLN 39.A N ILE 56.A O no hydrogen 3.002 N/A GLN 39.A NE2 TYR 14.A O no hydrogen 2.688 N/A VAL 40.A N GLY 33.A O no hydrogen 3.029 N/A VAL 41.A N ILE 54.A O no hydrogen 2.859 N/A LYS 42.A N SER 30.A O no hydrogen 2.927 N/A ALA 43.A N VAL 52.A O no hydrogen 3.074 N/A TYR 44.A N GLU 27.A O no hydrogen 2.901 N/A ASP 45.A N GLU 50.A O no hydrogen 2.828 N/A ARG 46.A N ARG 25.A O no hydrogen 3.152 N/A ARG 46.A NH1 GLU 27.A OE1 no hydrogen 2.910 N/A VAL 47.A N ASP 45.A OD1 no hydrogen 3.246 N/A GLU 50.A N ASP 45.A O no hydrogen 3.165 N/A VAL 52.A N ALA 43.A O no hydrogen 2.757 N/A ALA 53.A N PHE 105.A O no hydrogen 2.776 N/A ILE 54.A N VAL 41.A O no hydrogen 2.868 N/A LYS 55.A N LEU 103.A O no hydrogen 2.818 N/A LYS 55.A NZ GLU 70.A OE1 no hydrogen 3.276 N/A LYS 55.A NZ GLU 70.A OE2 no hydrogen 3.018 N/A ILE 56.A N GLN 39.A O no hydrogen 2.802 N/A ILE 57.A N LEU 101.A O no hydrogen 3.020 N/A LYS 58.A N PHE 37.A O no hydrogen 2.818 N/A LYS 58.A NZ SER 36.A O no hydrogen 2.843 N/A ASN 59.A N TYR 12.A O no hydrogen 3.088 N/A ASN 59.A ND2 ASP 8.A OD2 no hydrogen 3.507 N/A LYS 60.A N LYS 58.A O no hydrogen 2.854 N/A LEU 64.A N LYS 60.A O no hydrogen 2.934 N/A ASN 65.A N LYS 61.A O no hydrogen 2.779 N/A GLN 66.A N ALA 62.A O no hydrogen 3.300 N/A GLN 66.A NE2 GLY 176.A O no hydrogen 3.236 N/A ALA 67.A N PHE 63.A O no hydrogen 2.829 N/A GLN 68.A N LEU 64.A O no hydrogen 2.985 N/A GLU 70.A N GLN 66.A O no hydrogen 3.202 N/A VAL 71.A N ALA 67.A O no hydrogen 2.959 N/A ARG 72.A N GLN 68.A O no hydrogen 3.158 N/A ARG 72.A NH1 GLN 180.A OE1 no hydrogen 2.625 N/A ARG 72.A NH2 GLN 180.A OE1 no hydrogen 2.534 N/A LEU 73.A N ILE 69.A O no hydrogen 2.993 N/A LEU 74.A N GLU 70.A O no hydrogen 2.845 N/A GLU 75.A N VAL 71.A O no hydrogen 2.836 N/A LEU 76.A N ARG 72.A O no hydrogen 3.156 N/A MET 77.A N LEU 73.A O no hydrogen 3.087 N/A ASN 78.A N LEU 74.A O no hydrogen 2.960 N/A LYS 79.A N GLU 75.A O no hydrogen 3.127 N/A HIS 80.A N MET 77.A O no hydrogen 3.186 N/A MET 84.A N THR 82.A OG1 no hydrogen 3.298 N/A TYR 87.A N MET 84.A O no hydrogen 3.303 N/A ILE 88.A N LYS 85.A O no hydrogen 3.123 N/A VAL 89.A N ILE 172.A O no hydrogen 3.185 N/A HIS 90.A N GLU 106.A OE2 no hydrogen 2.973 N/A LYS 92.A N VAL 104.A O no hydrogen 2.780 N/A LYS 92.A NZ GLU 50.A OE2 no hydrogen 2.425 N/A ARG 93.A NH1 TYR 26.A OH no hydrogen 2.951 N/A ARG 93.A NH1 ASP 45.A OD2 no hydrogen 3.290 N/A PHE 95.A N CYS 102.A O no hydrogen 2.966 N/A PHE 97.A N HIS 100.A O no hydrogen 2.898 N/A ARG 98.A NH1 GLU 20.A OE2 no hydrogen 2.787 N/A ASN 99.A ND2 ASN 4.A OD1 no hydrogen 2.963 N/A HIS 100.A N PHE 97.A O no hydrogen 2.968 N/A HIS 100.A ND1 ILE 57.A O no hydrogen 2.878 N/A HIS 100.A NE2 ASP 8.A OD1 no hydrogen 2.708 N/A CYS 102.A N PHE 95.A O no hydrogen 2.863 N/A CYS 102.A SG HIS 100.A O no hydrogen 3.943 N/A LEU 103.A N LYS 55.A O no hydrogen 3.050 N/A VAL 104.A N ARG 93.A O no hydrogen 2.769 N/A PHE 105.A N ALA 53.A O no hydrogen 2.841 N/A GLU 106.A N HIS 90.A O no hydrogen 3.404 N/A SER 109.A N LEU 162.A O no hydrogen 2.627 N/A TYR 110.A N SER 109.A OG no hydrogen 2.547 N/A LEU 112.A N ILE 160.A O no hydrogen 2.870 N/A ASP 114.A N ASN 111.A OD1 no hydrogen 2.925 N/A LEU 115.A N ASN 111.A O no hydrogen 3.242 N/A LEU 116.A N LEU 112.A O no hydrogen 2.984 N/A ARG 117.A N TYR 113.A O no hydrogen 2.900 N/A ASN 118.A N ASP 114.A O no hydrogen 2.842 N/A THR 119.A N LEU 115.A O no hydrogen 3.276 N/A THR 119.A N LEU 116.A O no hydrogen 2.872 N/A THR 119.A OG1 LEU 116.A O no hydrogen 2.425 N/A ASN 120.A N ARG 117.A O no hydrogen 2.866 N/A PHE 121.A N LEU 116.A O no hydrogen 3.059 N/A ARG 122.A N THR 119.A O no hydrogen 3.170 N/A ARG 122.A N THR 119.A OG1 no hydrogen 3.195 N/A GLY 123.A N THR 119.A OG1 no hydrogen 3.139 N/A VAL 124.A N MET 220.A O no hydrogen 2.704 N/A LEU 126.A N HIS 305.A NE2 no hydrogen 3.159 N/A ASN 127.A ND2 SER 303.A O no hydrogen 3.343 N/A LEU 128.A N SER 125.A OG no hydrogen 3.109 N/A THR 129.A N SER 125.A O no hydrogen 3.027 N/A THR 129.A OG1 SER 125.A O no hydrogen 2.672 N/A ARG 130.A N LEU 126.A O no hydrogen 2.895 N/A ARG 130.A NE PHE 339.A O no hydrogen 2.787 N/A ARG 130.A NH1 ASN 127.A OD1 no hydrogen 3.459 N/A LYS 131.A N ASN 127.A O no hydrogen 3.312 N/A PHE 132.A N LEU 128.A O no hydrogen 2.969 N/A ALA 133.A N THR 129.A O no hydrogen 2.840 N/A GLN 134.A N ARG 130.A O no hydrogen 2.877 N/A GLN 135.A N LYS 131.A O no hydrogen 3.242 N/A GLN 135.A NE2 LYS 131.A O no hydrogen 3.022 N/A GLN 135.A NE2 SER 168.A O no hydrogen 2.621 N/A MET 136.A N PHE 132.A O no hydrogen 2.896 N/A CYS 137.A N ALA 133.A O no hydrogen 2.979 N/A CYS 137.A SG ALA 133.A O no hydrogen 3.277 N/A THR 138.A N GLN 134.A O no hydrogen 3.163 N/A THR 138.A OG1 GLN 134.A O no hydrogen 2.840 N/A ALA 139.A N GLN 135.A O no hydrogen 2.962 N/A LEU 140.A N MET 136.A O no hydrogen 3.036 N/A LEU 141.A N CYS 137.A O no hydrogen 3.098 N/A PHE 142.A N THR 138.A O no hydrogen 2.895 N/A LEU 143.A N ALA 139.A O no hydrogen 3.096 N/A ALA 144.A N LEU 140.A O no hydrogen 3.049 N/A THR 145.A N PHE 142.A O no hydrogen 3.083 N/A THR 145.A OG1 PHE 142.A O no hydrogen 2.545 N/A GLU 147.A N GLU 147.A OE1 no hydrogen 2.653 N/A LEU 148.A N THR 145.A O no hydrogen 2.734 N/A SER 149.A N THR 145.A O no hydrogen 2.840 N/A SER 149.A OG PRO 146.A O no hydrogen 3.026 N/A ILE 150.A N LEU 143.A O no hydrogen 2.947 N/A ILE 151.A N CYS 179.A O no hydrogen 2.957 N/A HIS 152.A N ASP 209.A OD2 no hydrogen 2.988 N/A HIS 152.A NE2 VAL 173.A O no hydrogen 2.865 N/A CYS 153.A N ASP 209.A OD1 no hydrogen 3.114 N/A CYS 153.A SG ILE 151.A O no hydrogen 3.527 N/A ASP 154.A N HIS 152.A ND1 no hydrogen 3.314 N/A LYS 156.A NZ GLU 158.A OE2 no hydrogen 2.607 N/A ASN 159.A N LYS 156.A O no hydrogen 2.987 N/A ASN 159.A ND2 ASP 154.A O no hydrogen 2.742 N/A ASN 159.A ND2 ASP 154.A OD2 no hydrogen 3.486 N/A ASN 159.A ND2 ASP 174.A OD2 no hydrogen 3.458 N/A ILE 160.A N PRO 157.A O no hydrogen 3.300 N/A LEU 161.A N LYS 171.A O no hydrogen 2.945 N/A LEU 162.A N TYR 110.A O no hydrogen 2.888 N/A CYS 163.A N ALA 169.A O no hydrogen 2.969 N/A LYS 166.A N ASN 164.A OD1 no hydrogen 2.836 N/A ARG 167.A N ASN 164.A O no hydrogen 3.286 N/A ILE 170.A N GLN 135.A OE1 no hydrogen 2.953 N/A LYS 171.A N LEU 161.A O no hydrogen 2.803 N/A LYS 171.A NZ GLU 106.A OE1 no hydrogen 3.388 N/A LYS 171.A NZ GLU 106.A OE2 no hydrogen 3.376 N/A ILE 172.A N TYR 87.A O no hydrogen 3.013 N/A VAL 173.A N ASN 159.A O no hydrogen 3.080 N/A SER 178.A N PHE 175.A O no hydrogen 3.156 N/A SER 178.A OG ILE 151.A O no hydrogen 2.678 N/A CYS 179.A N ILE 151.A O no hydrogen 3.326 N/A CYS 179.A SG SER 178.A O no hydrogen 3.115 N/A GLN 180.A NE2 LEU 148.A O no hydrogen 2.994 N/A LEU 181.A N SER 149.A O no hydrogen 2.654 N/A GLN 183.A N GLN 183.A OE1 no hydrogen 2.719 N/A GLN 189.A NE2 ILE 208.A O no hydrogen 3.340 N/A SER 190.A OG ASP 154.A OD1 no hydrogen 2.805 N/A ARG 191.A NH1 GLY 229.A O no hydrogen 3.124 N/A TYR 193.A N SER 190.A O no hydrogen 2.911 N/A TYR 193.A OH GLU 219.A OE1 no hydrogen 2.729 N/A TYR 193.A OH GLU 219.A OE2 no hydrogen 3.328 N/A ARG 194.A N ARG 191.A O no hydrogen 3.019 N/A ARG 194.A NE ILE 188.A O no hydrogen 3.153 N/A ARG 194.A NE GLN 189.A O no hydrogen 3.279 N/A ARG 194.A NH1 GLU 232.A OE2 no hydrogen 2.631 N/A ARG 194.A NH2 GLN 189.A O no hydrogen 2.757 N/A SER 195.A N GLN 189.A OE1 no hydrogen 2.907 N/A SER 195.A OG GLN 189.A OE1 no hydrogen 2.752 N/A GLU 197.A N GLU 197.A OE1 no hydrogen 2.872 N/A LEU 199.A N SER 195.A O no hydrogen 2.986 N/A LEU 200.A N PRO 196.A O no hydrogen 2.742 N/A GLY 201.A N VAL 198.A O no hydrogen 2.736 N/A MET 202.A N GLU 197.A O no hydrogen 2.762 N/A TYR 204.A OH TYR 186.A O no hydrogen 2.701 N/A ALA 207.A N ASP 205.A OD1 no hydrogen 2.724 N/A ILE 208.A N ASP 205.A O no hydrogen 3.425 N/A ASP 209.A N LEU 206.A O no hydrogen 3.185 N/A MET 210.A N ALA 207.A O no hydrogen 3.136 N/A TRP 211.A N ALA 207.A O no hydrogen 3.296 N/A SER 212.A N ILE 208.A O no hydrogen 3.266 N/A SER 212.A OG TYR 193.A O no hydrogen 2.688 N/A SER 212.A OG ILE 208.A O no hydrogen 3.096 N/A LEU 213.A N ASP 209.A O no hydrogen 2.915 N/A GLY 214.A N MET 210.A O no hydrogen 2.974 N/A CYS 215.A N TRP 211.A O no hydrogen 3.154 N/A CYS 215.A SG TRP 211.A O no hydrogen 3.422 N/A ILE 216.A N SER 212.A O no hydrogen 2.936 N/A LEU 217.A N LEU 213.A O no hydrogen 2.879 N/A VAL 218.A N GLY 214.A O no hydrogen 3.369 N/A GLU 219.A N CYS 215.A O no hydrogen 3.234 N/A MET 220.A N ILE 216.A O no hydrogen 3.011 N/A HIS 221.A N LEU 217.A O no hydrogen 3.382 N/A HIS 221.A ND1 VAL 124.A O no hydrogen 2.524 N/A HIS 221.A NE2 TYR 310.A OH no hydrogen 2.862 N/A THR 222.A N VAL 218.A O no hydrogen 2.969 N/A THR 222.A OG1 VAL 218.A O no hydrogen 2.804 N/A THR 222.A OG1 GLU 224.A O no hydrogen 3.202 N/A GLY 223.A N GLU 219.A O no hydrogen 2.712 N/A GLY 229.A N GLN 235.A OE1 no hydrogen 2.878 N/A ALA 230.A N ASP 234.A OD2 no hydrogen 3.000 N/A ASP 234.A N ASN 231.A OD1 no hydrogen 2.801 N/A GLN 235.A N ASN 231.A O no hydrogen 2.724 N/A GLN 235.A NE2 PHE 192.A O no hydrogen 3.262 N/A GLN 235.A NE2 PHE 227.A O no hydrogen 3.222 N/A MET 236.A N GLU 232.A O no hydrogen 2.935 N/A ASN 237.A N VAL 233.A O no hydrogen 3.108 N/A ASN 237.A ND2 VAL 233.A O no hydrogen 2.865 N/A LYS 238.A N ASP 234.A O no hydrogen 3.050 N/A LYS 238.A NZ SER 228.A O no hydrogen 2.855 N/A LYS 238.A NZ ASP 234.A OD2 no hydrogen 3.168 N/A ILE 239.A N GLN 235.A O no hydrogen 3.145 N/A VAL 240.A N MET 236.A O no hydrogen 2.999 N/A GLU 241.A N ASN 237.A O no hydrogen 3.001 N/A VAL 242.A N ILE 239.A O no hydrogen 3.099 N/A LEU 243.A N ILE 239.A O no hydrogen 2.954 N/A GLY 244.A N VAL 240.A O no hydrogen 2.717 N/A ILE 250.A N PRO 247.A O no hydrogen 3.140 N/A LEU 251.A N PRO 247.A O no hydrogen 3.195 N/A ASP 252.A N ALA 248.A O no hydrogen 2.760 N/A GLN 253.A N ILE 250.A O no hydrogen 3.001 N/A LYS 256.A N LEU 200.A O no hydrogen 3.046 N/A LYS 256.A NZ GLU 232.A OE1 no hydrogen 2.821 N/A LYS 259.A N LYS 256.A O no hydrogen 3.116 N/A LYS 259.A NZ GLU 232.A OE1 no hydrogen 2.788 N/A PHE 260.A N ALA 257.A O no hydrogen 2.980 N/A PHE 261.A N ALA 257.A O no hydrogen 2.860 N/A GLU 262.A N ASN 270.A O no hydrogen 2.828 N/A LEU 264.A N THR 268.A O no hydrogen 2.844 N/A GLY 267.A N LEU 264.A O no hydrogen 3.001 N/A THR 268.A N ASP 266.A OD1 no hydrogen 3.088 N/A THR 268.A OG1 ASP 266.A OD1 no hydrogen 2.881 N/A THR 268.A OG1 ASP 266.A OD2 no hydrogen 3.363 N/A THR 268.A OG1 ASN 270.A OD1 no hydrogen 3.498 N/A TRP 269.A NE1 ASP 252.A OD1 no hydrogen 2.551 N/A ASN 270.A N GLU 262.A O no hydrogen 3.134 N/A LYS 272.A N PHE 260.A O no hydrogen 3.165 N/A LYS 272.A NZ ARG 258.A O no hydrogen 2.721 N/A TYR 276.A OH ASP 234.A OD1 no hydrogen 2.521 N/A LYS 277.A N GLU 241.A OE2 no hydrogen 2.865 N/A GLY 280.A N VAL 240.A O no hydrogen 2.986 N/A THR 281.A OG1 PRO 278.A O no hydrogen 2.941 N/A ARG 282.A N GLU 241.A O no hydrogen 3.118 N/A ARG 282.A NH1 LEU 226.A O no hydrogen 3.029 N/A LYS 283.A NZ GLY 280.A O no hydrogen 2.713 N/A ASN 286.A N LYS 283.A O no hydrogen 2.946 N/A ILE 287.A N LYS 283.A O no hydrogen 3.105 N/A LEU 288.A N LEU 284.A O no hydrogen 2.940 N/A VAL 290.A N HIS 285.A O no hydrogen 3.162 N/A THR 292.A N GLY 289.A O no hydrogen 3.161 N/A GLY 294.A N GLY 289.A O no hydrogen 2.884 N/A GLY 297.A N GLY 294.A O no hydrogen 3.059 N/A ARG 298.A N PRO 295.A O no hydrogen 3.314 N/A ARG 298.A NH2 ARG 122.A O no hydrogen 3.032 N/A ARG 299.A N GLY 293.A O no hydrogen 2.885 N/A ARG 299.A NH1 GLU 302.A OE1 no hydrogen 2.780 N/A GLU 302.A N ARG 299.A O no hydrogen 3.061 N/A HIS 305.A N GLU 302.A O no hydrogen 3.031 N/A HIS 305.A ND1 GLU 302.A O no hydrogen 3.115 N/A HIS 305.A ND1 SER 303.A O no hydrogen 2.717 N/A THR 306.A N ASP 309.A OD2 no hydrogen 3.395 N/A THR 306.A OG1 ASP 309.A OD2 no hydrogen 2.809 N/A ASP 309.A N THR 306.A OG1 no hydrogen 3.374 N/A TYR 310.A N THR 306.A O no hydrogen 2.997 N/A TYR 310.A OH HIS 221.A NE2 no hydrogen 2.862 N/A LEU 311.A N VAL 307.A O no hydrogen 3.009 N/A LYS 312.A N ALA 308.A O no hydrogen 3.058 N/A LYS 312.A N ASP 309.A O no hydrogen 3.241 N/A PHE 313.A N ASP 309.A O no hydrogen 3.047 N/A LYS 314.A N TYR 310.A O no hydrogen 2.770 N/A ASP 315.A N LEU 311.A O no hydrogen 3.186 N/A LEU 316.A N LYS 312.A O no hydrogen 3.246 N/A ILE 317.A N PHE 313.A O no hydrogen 3.157 N/A LEU 318.A N LYS 314.A O no hydrogen 3.012 N/A ARG 319.A N ASP 315.A O no hydrogen 3.180 N/A ARG 319.A NH1 THR 327.A O no hydrogen 3.087 N/A ARG 319.A NH2 THR 327.A O no hydrogen 2.886 N/A MET 320.A N LEU 316.A O no hydrogen 2.931 N/A TYR 323.A OH GLY 244.A O no hydrogen 2.649 N/A ASP 324.A N ASP 322.A OD1 no hydrogen 2.851 N/A LYS 326.A N ASP 324.A OD1 no hydrogen 3.298 N/A THR 327.A N ASP 324.A O no hydrogen 3.131 N/A ARG 328.A N ASP 324.A O no hydrogen 2.865 N/A ARG 328.A NE ASP 322.A O no hydrogen 3.051 N/A ARG 328.A NH1 GLU 197.A OE2 no hydrogen 2.981 N/A ARG 328.A NH1 ALA 207.A O no hydrogen 2.809 N/A ARG 328.A NH2 GLU 197.A OE1 no hydrogen 2.864 N/A ARG 328.A NH2 GLU 197.A OE2 no hydrogen 3.446 N/A ARG 328.A NH2 ASP 322.A O no hydrogen 3.113 N/A ILE 329.A N ARG 319.A O no hydrogen 3.137 N/A ALA 334.A N GLN 330.A O no hydrogen 3.063 N/A LEU 335.A N PRO 331.A O no hydrogen 3.210 N/A GLN 336.A N TYR 332.A O no hydrogen 3.371 N/A HIS 337.A N ALA 334.A O no hydrogen 3.141 N/A HIS 337.A NE2 ASP 315.A OD2 no hydrogen 2.483 N/A PHE 339.A N HIS 337.A ND1 no hydrogen 3.387 N/A PHE 340.A N HIS 337.A O no hydrogen 2.946 N/A LYS 341.A N SER 338.A O no hydrogen 3.360 N/A