Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5afd_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 3.A NZ GLY 184.A O no hydrogen 2.817 N/A LYS 3.A NZ PHE 186.A O no hydrogen 3.556 N/A LEU 4.A N ASP 187.A OD2 no hydrogen 3.010 N/A GLY 6.A N LYS 205.A O no hydrogen 3.226 N/A ILE 8.A N ALA 207.A O no hydrogen 2.780 N/A ALA 9.A N GLY 40.A O no hydrogen 2.945 N/A ALA 10.A N GLY 209.A O no hydrogen 2.989 N/A THR 13.A OG1 GLY 48.A O no hydrogen 2.566 N/A PHE 15.A N ALA 268.A O no hydrogen 3.095 N/A ASP 16.A N ASN 20.A O no hydrogen 2.804 N/A SER 18.A N.A ASP 16.A OD1 no hydrogen 2.866 N/A SER 18.A N.B ASP 16.A OD1 no hydrogen 2.889 N/A SER 18.A OG.B ASP 16.A OD1 no hydrogen 2.675 N/A SER 18.A OG.B ASP 16.A OD2 no hydrogen 3.497 N/A SER 18.A OG.B ASN 20.A OD1 no hydrogen 3.160 N/A SER 19.A N ASP 16.A O no hydrogen 2.873 N/A ASN 20.A N ASP 16.A OD1 no hydrogen 2.913 N/A ASN 22.A N PRO 14.A O no hydrogen 2.982 N/A GLU 25.A N ASN 22.A OD1 no hydrogen 3.259 N/A ILE 26.A N ASN 22.A O no hydrogen 3.252 N/A ASP 27.A N PHE 23.A O no hydrogen 3.179 N/A LYS 28.A N GLU 24.A O no hydrogen 3.292 N/A LYS 28.A NZ GLU 25.A OE1 no hydrogen 2.987 N/A LYS 28.A NZ GLU 25.A OE2 no hydrogen 3.047 N/A LYS 28.A NZ ASP 265.A O no hydrogen 2.924 N/A ILE 29.A N GLU 25.A O no hydrogen 2.841 N/A ALA 30.A N ILE 26.A O no hydrogen 3.002 N/A LYS 31.A N ASP 27.A O no hydrogen 3.247 N/A HIS 32.A N LYS 28.A O no hydrogen 3.066 N/A HIS 32.A NE2 ASN 213.A O no hydrogen 2.773 N/A LEU 33.A N ILE 29.A O no hydrogen 2.819 N/A ILE 34.A N ALA 30.A O no hydrogen 2.994 N/A ASN 35.A N LYS 31.A O no hydrogen 2.994 N/A ASP 36.A N HIS 32.A O no hydrogen 2.949 N/A GLY 37.A N ILE 34.A O no hydrogen 3.390 N/A VAL 38.A N LEU 33.A O no hydrogen 3.176 N/A LYS 39.A N LEU 7.A O no hydrogen 2.889 N/A ILE 41.A N ASP 74.A O no hydrogen 2.951 N/A TYR 42.A N ALA 9.A O no hydrogen 2.877 N/A TYR 42.A OH SER 103.A OG no hydrogen 2.748 N/A VAL 43.A N ILE 76.A O.A no hydrogen 2.850 N/A VAL 43.A N ILE 76.A O.B no hydrogen 2.909 N/A GLU 49.A N THR 46.A O no hydrogen 2.857 N/A GLY 50.A N GLY 45.A O no hydrogen 3.040 N/A HIS 52.A N GLU 49.A O no hydrogen 2.869 N/A HIS 52.A ND1 GLU 49.A OE1 no hydrogen 2.871 N/A CYS 53.A N GLY 50.A O no hydrogen 2.953 N/A CYS 53.A SG GLU 49.A O no hydrogen 3.659 N/A SER 54.A N GLU 57.A OE1 no hydrogen 2.918 N/A GLU 57.A N SER 54.A OG no hydrogen 3.113 N/A ARG 58.A N SER 54.A O no hydrogen 2.886 N/A ARG 58.A NH1 GLY 80.A O no hydrogen 2.955 N/A ARG 58.A NH2 HIS 78.A O no hydrogen 2.966 N/A ARG 58.A NH2 GLY 80.A O no hydrogen 2.871 N/A LYS 59.A N VAL 55.A O no hydrogen 2.972 N/A LYS 59.A NZ GLU 56.A OE2 no hydrogen 3.253 N/A LYS 59.A NZ GLU 89.A OE2.A no hydrogen 2.871 N/A LYS 59.A NZ GLU 89.A OE2.B no hydrogen 2.767 N/A ALA 60.A N GLU 56.A O no hydrogen 3.207 N/A ILE 61.A N GLU 57.A O no hydrogen 2.818 N/A ALA 62.A N ARG 58.A O no hydrogen 2.955 N/A GLU 63.A N LYS 59.A O no hydrogen 3.041 N/A ARG 64.A N ALA 60.A O no hydrogen 2.936 N/A ARG 64.A NE ASP 27.A OD1 no hydrogen 2.964 N/A ARG 64.A NH2 ASP 27.A OD2 no hydrogen 2.754 N/A TRP 65.A N ILE 61.A O no hydrogen 2.932 N/A VAL 66.A N ALA 62.A O no hydrogen 3.104 N/A SER 67.A N GLU 63.A O no hydrogen 2.953 N/A SER 67.A OG GLU 63.A O no hydrogen 3.483 N/A SER 67.A OG ARG 64.A O no hydrogen 3.110 N/A ALA 68.A N ARG 64.A O no hydrogen 2.805 N/A CYS 69.A N TRP 65.A O no hydrogen 2.964 N/A CYS 69.A SG TRP 65.A O no hydrogen 3.370 N/A LYS 72.A N CYS 69.A O no hydrogen 2.928 N/A ASP 74.A N LYS 39.A O no hydrogen 3.227 N/A ILE 76.A N.A ILE 41.A O no hydrogen 2.856 N/A ILE 76.A N.B ILE 41.A O no hydrogen 2.871 N/A VAL 77.A N ALA 101.A O no hydrogen 2.967 N/A HIS 78.A N VAL 43.A O no hydrogen 2.858 N/A THR 79.A N SER 103.A O no hydrogen 2.889 N/A THR 79.A OG1 THR 91.A OG1 no hydrogen 2.795 N/A THR 79.A OG1 SER 103.A O no hydrogen 3.454 N/A VAL 85.A N SER 83.A OG no hydrogen 3.158 N/A THR 87.A N SER 83.A O no hydrogen 2.939 N/A THR 87.A OG1 ALA 81.A O no hydrogen 3.345 N/A THR 87.A OG1 SER 83.A O no hydrogen 3.188 N/A LEU 88.A N ILE 84.A O no hydrogen 2.803 N/A GLU 89.A N.A VAL 85.A O no hydrogen 2.935 N/A GLU 89.A N.B VAL 85.A O no hydrogen 2.947 N/A LEU 90.A N ASP 86.A O no hydrogen 2.990 N/A THR 91.A N THR 87.A O no hydrogen 2.841 N/A THR 91.A OG1 THR 79.A OG1 no hydrogen 2.795 N/A THR 91.A OG1 THR 87.A O no hydrogen 2.747 N/A ARG 92.A N.A LEU 88.A O no hydrogen 2.889 N/A ARG 92.A N.B LEU 88.A O no hydrogen 2.881 N/A HIS 93.A N GLU 89.A O.A no hydrogen 3.199 N/A HIS 93.A N GLU 89.A O.B no hydrogen 3.078 N/A HIS 93.A NE2 GLU 63.A OE2 no hydrogen 2.764 N/A ALA 94.A N LEU 90.A O no hydrogen 2.865 N/A ASP 95.A N THR 91.A O no hydrogen 3.002 N/A THR 96.A N HIS 93.A O no hydrogen 2.947 N/A THR 96.A OG1 HIS 93.A O no hydrogen 2.689 N/A LEU 97.A N ALA 94.A O no hydrogen 3.073 N/A LEU 100.A N ILE 75.A O no hydrogen 2.802 N/A THR 102.A N GLY 133.A O no hydrogen 2.931 N/A SER 103.A OG TYR 42.A OH no hydrogen 2.748 N/A SER 103.A OG TYR 135.A O no hydrogen 2.767 N/A ALA 104.A N TYR 135.A O no hydrogen 3.320 N/A LYS 111.A NZ CYS 108.A O no hydrogen 2.860 N/A LYS 111.A NZ PHE 109.A O no hydrogen 3.445 N/A SER 114.A OG SER 116.A OG.B no hydrogen 2.974 N/A SER 116.A OG.B SER 114.A OG no hydrogen 2.974 N/A ASP 117.A N SER 114.A OG no hydrogen 3.109 N/A LEU 118.A N SER 114.A O no hydrogen 2.956 N/A VAL 119.A N VAL 115.A O no hydrogen 2.798 N/A GLU 120.A N.A SER 116.A O.A no hydrogen 3.039 N/A GLU 120.A N.A SER 116.A O.B no hydrogen 2.920 N/A GLU 120.A N.B SER 116.A O.A no hydrogen 3.032 N/A GLU 120.A N.B SER 116.A O.B no hydrogen 2.912 N/A TYR 121.A N ASP 117.A O no hydrogen 3.096 N/A CYS 122.A N LEU 118.A O no hydrogen 2.810 N/A CYS 122.A SG LEU 118.A O no hydrogen 3.507 N/A ALA 123.A N VAL 119.A O no hydrogen 2.817 N/A THR 124.A N GLU 120.A O.A no hydrogen 3.076 N/A THR 124.A N GLU 120.A O.B no hydrogen 3.146 N/A THR 124.A OG1 GLU 120.A O.A no hydrogen 2.928 N/A THR 124.A OG1 GLU 120.A O.B no hydrogen 2.914 N/A ILE 125.A N TYR 121.A O no hydrogen 3.222 N/A ALA 126.A N CYS 122.A O no hydrogen 2.864 N/A ALA 127.A N ALA 123.A O no hydrogen 3.113 N/A ALA 128.A N ILE 125.A O no hydrogen 2.995 N/A ALA 129.A N ALA 126.A O no hydrogen 3.047 N/A SER 131.A N ASP 95.A OD1 no hydrogen 3.066 N/A SER 131.A OG ASP 95.A OD1 no hydrogen 2.592 N/A LYS 132.A N ALA 129.A O no hydrogen 3.061 N/A LYS 132.A NZ ASP 95.A O no hydrogen 3.312 N/A LYS 132.A NZ LEU 97.A O no hydrogen 3.129 N/A LYS 132.A NZ SER 131.A OG no hydrogen 3.218 N/A GLY 133.A N LEU 100.A O no hydrogen 3.091 N/A PHE 134.A N SER 163.A OG no hydrogen 3.083 N/A TYR 135.A N THR 102.A O no hydrogen 2.967 N/A TYR 135.A OH ASP 187.A OD2 no hydrogen 2.644 N/A TYR 136.A N GLY 164.A O no hydrogen 3.129 N/A TYR 137.A N ALA 104.A O no hydrogen 2.858 N/A HIS 138.A N LYS 166.A O no hydrogen 2.857 N/A GLY 140.A N.B ASN 168.A O no hydrogen 3.409 N/A MET 141.A N.A SER 139.A O.A no hydrogen 2.516 N/A MET 141.A N.B SER 139.A O.A no hydrogen 2.512 N/A MET 141.A N.B SER 139.A OG.B no hydrogen 3.055 N/A SER 142.A N SER 139.A O.B no hydrogen 3.168 N/A SER 142.A OG SER 139.A O.B no hydrogen 2.793 N/A GLY 143.A N GLY 140.A O.A no hydrogen 2.777 N/A VAL 144.A N SER 142.A OG no hydrogen 3.029 N/A MET 148.A N GLU 174.A OE2 no hydrogen 2.849 N/A GLU 150.A N ASN 147.A OD1 no hydrogen 3.125 N/A PHE 151.A N ASN 147.A O no hydrogen 2.922 N/A LEU 152.A N MET 148.A O no hydrogen 3.040 N/A ILE 153.A N GLU 149.A O no hydrogen 3.069 N/A GLN 154.A N GLU 150.A O no hydrogen 2.773 N/A ALA 155.A N PHE 151.A O no hydrogen 2.725 N/A ASP 156.A N LEU 152.A O no hydrogen 2.951 N/A ARG 158.A N ALA 155.A O no hydrogen 2.966 N/A ILE 159.A N ALA 155.A O no hydrogen 2.743 N/A ASN 161.A ND2 ALA 126.A O no hydrogen 3.031 N/A ASN 161.A ND2 ALA 129.A O no hydrogen 3.096 N/A ASN 161.A ND2 LYS 132.A O no hydrogen 2.957 N/A LEU 162.A N ILE 159.A O no hydrogen 3.206 N/A SER 163.A N PHE 134.A O no hydrogen 2.785 N/A LEU 165.A N ASP 187.A O no hydrogen 3.088 N/A LYS 166.A N TYR 136.A O no hydrogen 2.840 N/A PHE 167.A N PRO 189.A O no hydrogen 2.902 N/A ASN 168.A N HIS 138.A O no hydrogen 2.813 N/A ASN 168.A ND2 SER 139.A OG.B no hydrogen 2.990 N/A ASP 171.A N SER 169.A OG no hydrogen 2.989 N/A GLU 174.A N ASP 171.A OD1 no hydrogen 2.948 N/A TYR 175.A N ASP 171.A O no hydrogen 2.935 N/A TYR 175.A OH VAL 188.A O no hydrogen 2.897 N/A GLN 176.A N LEU 172.A O no hydrogen 3.057 N/A ARG 177.A N TYR 173.A O no hydrogen 3.216 N/A ARG 177.A NH1 ASN 147.A OD1 no hydrogen 3.542 N/A ARG 177.A NH1 GLU 149.A OE1 no hydrogen 2.997 N/A CYS 178.A N GLU 174.A O no hydrogen 2.922 N/A CYS 178.A SG GLU 174.A O no hydrogen 3.474 N/A LEU 179.A N TYR 175.A O no hydrogen 2.954 N/A ARG 180.A N GLN 176.A O no hydrogen 3.292 N/A ARG 180.A N ARG 177.A O no hydrogen 3.130 N/A ARG 180.A NH1 GLN 176.A O no hydrogen 3.050 N/A ALA 181.A N CYS 178.A O no hydrogen 3.208 N/A GLY 184.A N ARG 180.A O no hydrogen 3.221 N/A GLY 184.A N ALA 181.A O no hydrogen 2.947 N/A LYS 185.A N ALA 181.A O no hydrogen 3.345 N/A LYS 185.A N CYS 182.A O no hydrogen 3.105 N/A LYS 185.A NZ ASP 156.A OD1 no hydrogen 2.733 N/A ASP 187.A N SER 163.A O no hydrogen 2.956 N/A PHE 190.A N SER 206.A O no hydrogen 3.042 N/A GLY 191.A N PHE 167.A O no hydrogen 2.767 N/A GLU 194.A N GLU 194.A OE1 no hydrogen 2.728 N/A PHE 195.A N VAL 192.A O no hydrogen 3.018 N/A LEU 196.A N ASP 193.A O no hydrogen 2.940 N/A ALA 199.A N PHE 195.A O no hydrogen 3.231 N/A LEU 200.A N LEU 196.A O no hydrogen 2.891 N/A ALA 201.A N PRO 197.A O no hydrogen 2.961 N/A VAL 202.A N ALA 199.A O no hydrogen 3.125 N/A GLY 203.A N LEU 200.A O no hydrogen 3.130 N/A ALA 204.A N ALA 199.A O no hydrogen 2.869 N/A ALA 207.A N GLY 6.A O no hydrogen 2.956 N/A VAL 208.A N PHE 190.A O no hydrogen 2.821 N/A GLY 209.A N ILE 8.A O no hydrogen 3.056 N/A THR 211.A N ASP 193.A OD2 no hydrogen 2.896 N/A THR 211.A OG1 ASP 193.A OD2 no hydrogen 2.631 N/A ASN 213.A N SER 210.A O no hydrogen 3.147 N/A TYR 214.A N THR 211.A O no hydrogen 3.057 N/A ALA 215.A N THR 211.A O no hydrogen 2.798 N/A HIS 218.A NE2 LYS 237.A O no hydrogen 2.867 N/A PHE 219.A N ALA 215.A O no hydrogen 3.077 N/A ASN 220.A N ALA 216.A O no hydrogen 2.711 N/A SER 221.A N PRO 217.A O no hydrogen 2.902 N/A SER 221.A OG HIS 218.A O no hydrogen 2.648 N/A ILE 222.A N HIS 218.A O no hydrogen 3.098 N/A ILE 223.A N PHE 219.A O no hydrogen 3.010 N/A GLU 224.A N ASN 220.A O no hydrogen 3.006 N/A ALA 225.A N SER 221.A O no hydrogen 2.969 N/A PHE 226.A N ILE 222.A O no hydrogen 2.886 N/A ASN 227.A N ILE 223.A O no hydrogen 2.982 N/A LYS 228.A N GLU 224.A O no hydrogen 3.118 N/A GLY 229.A N PHE 226.A O no hydrogen 2.877 N/A ASP 230.A N ALA 225.A O no hydrogen 2.825 N/A HIS 231.A N GLY 229.A O no hydrogen 3.027 N/A ALA 233.A N ASP 230.A OD1 no hydrogen 3.077 N/A VAL 234.A N ASP 230.A O no hydrogen 3.066 N/A PHE 235.A N HIS 231.A O no hydrogen 2.882 N/A ASN 236.A N ASP 232.A O no hydrogen 3.107 N/A LYS 237.A N ALA 233.A O no hydrogen 2.990 N/A LYS 237.A NZ SER 221.A OG no hydrogen 3.026 N/A MET 238.A N VAL 234.A O no hydrogen 2.852 N/A THR 239.A N PHE 235.A O no hydrogen 3.199 N/A THR 239.A OG1 PHE 235.A O no hydrogen 3.391 N/A ASN 240.A ND2 LYS 237.A O no hydrogen 3.366 N/A VAL 241.A N LYS 237.A O no hydrogen 3.321 N/A ILE 242.A N MET 238.A O no hydrogen 2.877 N/A GLU 243.A N THR 239.A O no hydrogen 3.196 N/A LEU 244.A N ASN 240.A O no hydrogen 2.988 N/A ILE 245.A N VAL 241.A O no hydrogen 2.864 N/A ARG 246.A N ILE 242.A O no hydrogen 2.897 N/A ARG 246.A NE GLU 243.A OE2 no hydrogen 2.852 N/A VAL 247.A N LEU 244.A O no hydrogen 2.971 N/A LEU 248.A N LEU 244.A O no hydrogen 3.389 N/A VAL 249.A N ILE 245.A O no hydrogen 2.901 N/A GLU 250.A N ARG 246.A O no hydrogen 3.051 N/A PHE 251.A N VAL 247.A O no hydrogen 2.956 N/A GLY 252.A N LEU 248.A O no hydrogen 2.800 N/A ALA 256.A N GLY 252.A O no hydrogen 2.853 N/A GLY 257.A N GLY 253.A O no hydrogen 2.960 N/A LYS 258.A N VAL 254.A O no hydrogen 2.908 N/A LYS 258.A NZ THR 13.A O no hydrogen 2.753 N/A LYS 258.A NZ GLU 49.A OE2 no hydrogen 2.771 N/A LYS 258.A NZ ASP 270.A O no hydrogen 3.029 N/A ILE 259.A N ALA 255.A O no hydrogen 3.107 N/A ALA 260.A N ALA 256.A O no hydrogen 2.776 N/A MET 261.A N GLY 257.A O no hydrogen 3.313 N/A MET 261.A N LYS 258.A O no hydrogen 3.073 N/A GLU 262.A N ILE 259.A O no hydrogen 2.821 N/A LEU 263.A N ALA 260.A O no hydrogen 2.936 N/A HIS 264.A N MET 261.A O no hydrogen 2.884 N/A HIS 264.A NE2 TYR 214.A O no hydrogen 2.990 N/A ASP 265.A N GLU 262.A O no hydrogen 3.085 N/A ILE 266.A N MET 261.A O no hydrogen 3.068 N/A ASN 267.A N GLU 25.A OE1 no hydrogen 2.929 N/A ARG 272.A N GLU 49.A OE1 no hydrogen 2.796 N/A ARG 272.A NE SER 19.A O no hydrogen 3.217 N/A ARG 272.A NE SER 19.A OG no hydrogen 3.377 N/A ARG 272.A NH1 HIS 52.A O no hydrogen 2.968 N/A ARG 272.A NH1 GLU 57.A OE1 no hydrogen 2.812 N/A ARG 272.A NH2 SER 19.A O no hydrogen 2.631 N/A ARG 272.A NH2 GLU 57.A OE2 no hydrogen 2.950 N/A LEU 275.A N ARG 272.A O no hydrogen 3.037 N/A SER 279.A N GLN 282.A OE1 no hydrogen 2.977 N/A SER 279.A OG GLN 282.A OE1 no hydrogen 3.363 N/A GLN 282.A N SER 279.A OG no hydrogen 3.112 N/A LYS 283.A N SER 279.A O no hydrogen 2.954 N/A LYS 283.A NZ ASP 270.A OD1 no hydrogen 2.812 N/A LEU 284.A N ALA 280.A O no hydrogen 3.244 N/A THR 285.A N GLU 281.A O no hydrogen 3.056 N/A THR 285.A OG1 GLU 281.A O no hydrogen 3.208 N/A VAL 286.A N GLN 282.A O no hydrogen 2.852 N/A VAL 287.A N LYS 283.A O no hydrogen 3.284 N/A GLU 288.A N LEU 284.A O no hydrogen 3.030 N/A LYS 289.A N THR 285.A O no hydrogen 2.838 N/A MET 290.A N VAL 286.A O no hydrogen 2.906 N/A ARG 291.A N VAL 287.A O no hydrogen 2.896 N/A ALA 292.A N GLU 288.A O no hydrogen 2.920 N/A ALA 293.A N LYS 289.A O no hydrogen 2.972 N/A ALA 293.A N MET 290.A O no hydrogen 3.216 N/A ASN 294.A N ARG 291.A O no hydrogen 3.068 N/A HIS 299.A ND1 HIS 300.A O no hydrogen 3.090 N/A