Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5bo7_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 5.A N GLY 280.A O no hydrogen 2.760 N/A ALA 8.A N ASN 5.A OD1 no hydrogen 3.020 N/A PHE 9.A N ASN 5.A O no hydrogen 2.963 N/A LEU 10.A N ARG 6.A O no hydrogen 2.867 N/A HIS 11.A N THR 7.A O no hydrogen 3.047 N/A GLN 12.A N ALA 8.A O no hydrogen 2.968 N/A GLN 12.A NE2 TYR 200.A OH no hydrogen 3.134 N/A ARG 13.A N PHE 9.A O no hydrogen 2.805 N/A ARG 13.A NE SER 222.A O no hydrogen 2.747 N/A ARG 13.A NH2 CYS 225.A O no hydrogen 2.767 N/A ARG 13.A NH2 GLU 226.A OE1 no hydrogen 3.025 N/A GLN 14.A N LEU 10.A O no hydrogen 2.978 N/A GLU 15.A N HIS 11.A O no hydrogen 2.952 N/A ILE 16.A N GLN 12.A O no hydrogen 2.912 N/A LEU 17.A N ARG 13.A O no hydrogen 2.946 N/A GLN 18.A N GLN 14.A O no hydrogen 3.055 N/A HIS 19.A N ILE 16.A O no hydrogen 2.933 N/A HIS 19.A ND1 GLU 15.A O no hydrogen 2.877 N/A VAL 20.A N ILE 16.A O no hydrogen 2.801 N/A LYS 24.A N ASP 21.A OD1 no hydrogen 3.238 N/A ASN 25.A N ASP 21.A O no hydrogen 2.702 N/A PHE 26.A N VAL 22.A O no hydrogen 2.861 N/A SER 27.A N LYS 24.A O no hydrogen 3.332 N/A SER 27.A OG LEU 28.A O no hydrogen 2.668 N/A LEU 28.A N TRP 189.A O no hydrogen 2.858 N/A THR 29.A N SER 32.A OG no hydrogen 3.086 N/A THR 29.A OG1 SER 32.A OG no hydrogen 3.367 N/A LYS 30.A N PRO 61.A O no hydrogen 3.011 N/A LYS 30.A NZ LEU 60.A O no hydrogen 2.779 N/A LYS 30.A NZ ASP 62.A OD1 no hydrogen 2.926 N/A SER 32.A N THR 29.A O no hydrogen 2.992 N/A SER 32.A OG THR 29.A O no hydrogen 3.121 N/A SER 32.A OG THR 29.A OG1 no hydrogen 3.367 N/A VAL 33.A N LYS 30.A O no hydrogen 3.361 N/A ARG 34.A N GLN 37.A OE1 no hydrogen 2.966 N/A GLY 36.A N ILE 52.A O no hydrogen 2.683 N/A GLN 37.A N ARG 34.A O no hydrogen 3.039 N/A MET 39.A N PHE 50.A O no hydrogen 2.813 N/A HIS 40.A ND1 HIS 46.A O no hydrogen 2.716 N/A ASP 42.A N PHE 160.A O no hydrogen 2.856 N/A TYR 43.A N PHE 161.A O no hydrogen 2.823 N/A SER 44.A OG HIS 163.A ND1 no hydrogen 3.149 N/A TYR 48.A N SER 45.A O no hydrogen 3.295 N/A PHE 50.A N MET 39.A O no hydrogen 2.923 N/A ILE 52.A N GLN 37.A O no hydrogen 2.885 N/A PHE 56.A N SER 53.A OG no hydrogen 2.961 N/A ARG 57.A N SER 53.A O no hydrogen 2.975 N/A ARG 57.A NE LYS 30.A O no hydrogen 3.006 N/A ARG 57.A NE VAL 33.A O no hydrogen 3.292 N/A SER 58.A N ASN 54.A O no hydrogen 2.987 N/A SER 58.A OG ASN 55.A O no hydrogen 2.638 N/A LEU 59.A N PHE 56.A O no hydrogen 2.980 N/A LEU 60.A N ARG 57.A O no hydrogen 3.006 N/A SER 64.A OG ILE 23.A O no hydrogen 2.738 N/A ILE 66.A N SER 64.A OG no hydrogen 3.306 N/A MET 67.A N SER 64.A O no hydrogen 3.025 N/A LYS 69.A N ILE 66.A O no hydrogen 3.249 N/A TYR 71.A N ILE 224.A O no hydrogen 2.889 N/A ILE 73.A N ASP 96.A OD2 no hydrogen 2.920 N/A CYS 74.A N GLU 227.A O no hydrogen 2.913 N/A ALA 75.A N PHE 97.A O no hydrogen 2.913 N/A VAL 76.A N HIS 229.A O no hydrogen 2.996 N/A VAL 77.A N PHE 99.A O no hydrogen 2.884 N/A GLY 78.A N TYR 231.A O no hydrogen 2.776 N/A ASN 79.A ND2 CYS 101.A O no hydrogen 3.052 N/A SER 80.A N GLY 232.A O no hydrogen 2.952 N/A SER 80.A OG TRP 234.A O no hydrogen 2.894 N/A GLY 81.A N TYR 248.A O no hydrogen 3.215 N/A ILE 82.A N SER 80.A OG no hydrogen 2.914 N/A LEU 83.A N SER 80.A O no hydrogen 3.158 N/A THR 84.A N GLY 81.A O no hydrogen 3.075 N/A THR 84.A OG1 TYR 250.A O no hydrogen 2.982 N/A GLY 85.A N ASP 112.A OD2 no hydrogen 2.773 N/A SER 86.A N LEU 83.A O no hydrogen 2.926 N/A SER 86.A OG LEU 83.A O no hydrogen 2.773 N/A GLN 87.A N ASP 112.A OD1 no hydrogen 2.906 N/A CYS 88.A N SER 86.A OG no hydrogen 3.258 N/A CYS 88.A SG SER 86.A O no hydrogen 3.869 N/A CYS 88.A SG SER 86.A OG no hydrogen 3.384 N/A CYS 88.A SG SER 287.A O no hydrogen 4.026 N/A GLY 89.A N ARG 111.A O no hydrogen 2.916 N/A ILE 92.A N CYS 88.A O no hydrogen 2.908 N/A ASP 93.A N GLY 89.A O no hydrogen 2.953 N/A LYS 94.A N GLN 90.A O no hydrogen 3.049 N/A SER 95.A N ILE 92.A O no hydrogen 3.061 N/A SER 95.A OG ILE 92.A O no hydrogen 2.693 N/A ASP 96.A N ILE 73.A O no hydrogen 2.722 N/A PHE 97.A N ILE 73.A O no hydrogen 3.323 N/A VAL 98.A N ASN 118.A OD1 no hydrogen 2.882 N/A PHE 99.A N ALA 75.A O no hydrogen 2.832 N/A ARG 100.A N LEU 119.A O no hydrogen 2.817 N/A ARG 100.A NE LYS 116.A O no hydrogen 3.141 N/A ARG 100.A NE THR 117.A OG1 no hydrogen 2.921 N/A ARG 100.A NH1 VAL 113.A O no hydrogen 2.776 N/A ARG 100.A NH1 LYS 116.A O no hydrogen 2.814 N/A ARG 100.A NH2 VAL 113.A O no hydrogen 2.847 N/A CYS 101.A SG VAL 77.A O no hydrogen 3.463 N/A ASN 102.A N THR 121.A OG1 no hydrogen 2.809 N/A PHE 103.A N THR 120.A OG1 no hydrogen 3.259 N/A PHE 109.A N THR 106.A O no hydrogen 2.922 N/A ASP 112.A N PHE 109.A O no hydrogen 2.941 N/A VAL 113.A N PHE 109.A O no hydrogen 2.983 N/A GLY 114.A N GLN 110.A O no hydrogen 2.788 N/A ARG 115.A N ASP 93.A OD2 no hydrogen 2.801 N/A ARG 115.A NH1 GLN 110.A OE1 no hydrogen 2.920 N/A LYS 116.A N ASP 93.A OD1 no hydrogen 2.882 N/A LYS 116.A NZ ASP 93.A O no hydrogen 2.799 N/A LYS 116.A NZ SER 95.A O no hydrogen 2.901 N/A ASN 118.A N VAL 98.A O no hydrogen 2.817 N/A LEU 119.A N VAL 98.A O no hydrogen 3.152 N/A THR 120.A N ILE 154.A O no hydrogen 2.905 N/A THR 121.A N ARG 100.A O no hydrogen 3.191 N/A THR 121.A OG1 ASN 102.A OD1 no hydrogen 3.460 N/A PHE 122.A N TRP 156.A O no hydrogen 2.930 N/A SER 125.A N ASN 123.A OD1 no hydrogen 2.808 N/A SER 125.A OG ASN 123.A OD1 no hydrogen 3.111 N/A ILE 126.A N ASN 123.A O no hydrogen 2.931 N/A LEU 127.A N PRO 124.A O no hydrogen 2.993 N/A LYS 129.A N SER 125.A O no hydrogen 3.006 N/A TYR 130.A N ILE 126.A O no hydrogen 2.839 N/A TYR 131.A N LEU 127.A O no hydrogen 3.027 N/A TYR 131.A OH SER 146.A OG no hydrogen 2.835 N/A ASN 132.A ND2 ASP 139.A OD2 no hydrogen 2.914 N/A ASN 133.A N LEU 127.A O no hydrogen 2.965 N/A LEU 134.A N TYR 131.A O no hydrogen 2.914 N/A LEU 135.A N ASN 132.A O no hydrogen 3.148 N/A THR 136.A N ASP 139.A OD2 no hydrogen 3.154 N/A THR 136.A OG1 ASP 139.A OD2 no hydrogen 2.636 N/A GLN 138.A NE2 GLN 138.A O no hydrogen 3.340 N/A ASP 139.A N THR 136.A OG1 no hydrogen 3.129 N/A ARG 140.A N THR 136.A O no hydrogen 2.998 N/A ARG 140.A NH1 GLU 178.A OE1 no hydrogen 3.512 N/A ARG 140.A NH1 GLU 178.A OE2 no hydrogen 2.754 N/A ARG 140.A NH2 GLU 178.A OE1 no hydrogen 2.798 N/A ARG 140.A NH2 GLU 178.A OE2 no hydrogen 3.497 N/A ASN 141.A N ILE 137.A O no hydrogen 2.846 N/A ASN 142.A N GLN 138.A O no hydrogen 2.868 N/A PHE 143.A N ASP 139.A O no hydrogen 2.925 N/A PHE 144.A N ARG 140.A O no hydrogen 2.881 N/A LEU 145.A N ASN 141.A O no hydrogen 2.867 N/A SER 146.A N ASN 142.A O no hydrogen 3.035 N/A SER 146.A OG TYR 131.A OH no hydrogen 2.835 N/A SER 146.A OG ASN 142.A O no hydrogen 3.189 N/A LEU 147.A N PHE 143.A O no hydrogen 2.982 N/A LYS 148.A N PHE 144.A O no hydrogen 2.881 N/A LYS 149.A N LEU 145.A O no hydrogen 3.148 N/A LYS 149.A NZ GLU 107.A OE2 no hydrogen 2.977 N/A LEU 150.A N LEU 147.A O no hydrogen 2.968 N/A ASP 151.A N LYS 148.A O no hydrogen 2.979 N/A ALA 153.A N LEU 150.A O no hydrogen 3.032 N/A ILE 154.A N ASN 118.A O no hydrogen 2.864 N/A LEU 155.A N GLN 186.A O no hydrogen 2.833 N/A TRP 156.A N THR 120.A O no hydrogen 2.966 N/A TRP 156.A NE1 PHE 26.A O no hydrogen 2.767 N/A ILE 157.A N ALA 188.A O no hydrogen 2.855 N/A HIS 163.A N SER 44.A OG no hydrogen 2.882 N/A HIS 163.A ND1 SER 44.A OG no hydrogen 3.149 N/A SER 165.A N PHE 162.A O no hydrogen 2.894 N/A SER 165.A OG ASN 123.A OD1 no hydrogen 3.254 N/A SER 165.A OG PHE 162.A O no hydrogen 3.129 N/A ALA 166.A N HIS 163.A O no hydrogen 3.102 N/A THR 169.A N SER 165.A O no hydrogen 2.907 N/A THR 169.A OG1 SER 165.A O no hydrogen 2.681 N/A ARG 170.A N THR 167.A O no hydrogen 3.176 N/A LEU 172.A N VAL 168.A O no hydrogen 2.963 N/A VAL 173.A N THR 169.A O no hydrogen 2.905 N/A ASP 174.A N ARG 170.A O no hydrogen 2.960 N/A PHE 175.A N THR 171.A O no hydrogen 2.930 N/A PHE 176.A N LEU 172.A O no hydrogen 2.978 N/A VAL 177.A N VAL 173.A O no hydrogen 2.898 N/A GLU 178.A N ASP 174.A O no hydrogen 2.899 N/A HIS 179.A N PHE 175.A O no hydrogen 3.102 N/A HIS 179.A ND1 PHE 175.A O no hydrogen 2.826 N/A ARG 180.A N VAL 177.A O no hydrogen 3.177 N/A ARG 180.A NH1 SER 58.A OG no hydrogen 2.849 N/A ARG 180.A NH2 SER 58.A O no hydrogen 3.277 N/A ARG 180.A NH2 SER 58.A OG no hydrogen 3.188 N/A GLN 182.A N HIS 179.A O no hydrogen 2.884 N/A GLN 186.A N ALA 153.A O no hydrogen 2.857 N/A GLN 186.A NE2 GLY 152.A O no hydrogen 2.994 N/A ALA 188.A N LEU 155.A O no hydrogen 2.927 N/A TRP 189.A N SER 27.A OG no hydrogen 2.926 N/A ASN 192.A ND2 HIS 40.A O no hydrogen 2.967 N/A ASN 192.A ND2 ASP 42.A OD1 no hydrogen 2.837 N/A MET 194.A N ASP 42.A OD2 no hydrogen 2.921 N/A HIS 196.A N ILE 193.A O no hydrogen 3.010 N/A VAL 197.A N ILE 193.A O no hydrogen 3.183 N/A ASN 198.A N MET 194.A O no hydrogen 2.752 N/A ARG 199.A N HIS 196.A O no hydrogen 3.223 N/A TRP 201.A NE1 THR 219.A OG1 no hydrogen 2.920 N/A LYS 202.A N ASN 198.A O no hydrogen 2.829 N/A ASN 203.A N ARG 199.A O no hydrogen 3.407 N/A LYS 204.A N TRP 201.A O no hydrogen 2.966 N/A LYS 204.A NZ GLU 15.A OE1 no hydrogen 2.991 N/A LYS 204.A NZ GLU 15.A OE2 no hydrogen 3.069 N/A HIS 205.A N LYS 202.A O no hydrogen 2.970 N/A LEU 206.A N TRP 201.A O no hydrogen 3.093 N/A ARG 210.A N SER 263.A O no hydrogen 3.215 N/A SER 212.A N GLU 269.A OE2 no hydrogen 2.769 N/A SER 212.A OG GLU 269.A OE1 no hydrogen 2.498 N/A SER 212.A OG GLU 269.A OE2 no hydrogen 3.472 N/A ILE 215.A N SER 212.A OG no hydrogen 3.334 N/A LEU 216.A N SER 212.A O no hydrogen 3.036 N/A MET 217.A N THR 213.A O no hydrogen 2.845 N/A TYR 218.A N GLY 214.A O no hydrogen 2.980 N/A TYR 218.A OH GLN 12.A OE1 no hydrogen 2.665 N/A THR 219.A N ILE 215.A O no hydrogen 2.981 N/A THR 219.A OG1 ILE 215.A O no hydrogen 2.777 N/A LEU 220.A N LEU 216.A O no hydrogen 3.039 N/A ALA 221.A N MET 217.A O no hydrogen 2.849 N/A SER 222.A N TYR 218.A O no hydrogen 2.917 N/A SER 222.A OG THR 219.A O no hydrogen 2.646 N/A ALA 223.A N LEU 220.A O no hydrogen 3.161 N/A ILE 224.A N ALA 221.A O no hydrogen 3.040 N/A CYS 225.A N ALA 221.A O no hydrogen 2.890 N/A CYS 225.A SG ALA 221.A O no hydrogen 3.293 N/A GLU 226.A N TYR 71.A O no hydrogen 2.888 N/A HIS 229.A N CYS 74.A O no hydrogen 2.837 N/A HIS 229.A NE2 GLU 227.A OE2 no hydrogen 2.841 N/A LEU 230.A N LYS 283.A O no hydrogen 2.755 N/A TYR 231.A N VAL 76.A O no hydrogen 2.965 N/A TYR 231.A OH GLU 91.A OE1 no hydrogen 2.715 N/A TRP 234.A NE1 PHE 238.A O no hydrogen 2.719 N/A ASP 239.A N GLU 244.A O no hydrogen 2.756 N/A ASN 241.A N ASP 239.A OD2 no hydrogen 2.781 N/A ASN 241.A ND2 LEU 286.A O no hydrogen 3.079 N/A THR 242.A N ASP 239.A OD2 no hydrogen 3.004 N/A ARG 243.A N ASP 239.A O no hydrogen 2.845 N/A ARG 243.A NH2 PRO 240.A O no hydrogen 3.245 N/A GLU 244.A N THR 242.A OG1 no hydrogen 3.296 N/A LEU 246.A N GLY 237.A O no hydrogen 2.880 N/A HIS 249.A N ASP 252.A OD2 no hydrogen 3.007 N/A TYR 250.A N ASN 79.A O no hydrogen 2.975 N/A TYR 250.A OH PRO 105.A O no hydrogen 2.526 N/A ASP 252.A N HIS 249.A O no hydrogen 3.081 N/A THR 256.A N LYS 253.A O no hydrogen 3.054 N/A THR 256.A OG1 LYS 253.A O no hydrogen 2.728 N/A LYS 257.A NZ ASP 245.A OD2 no hydrogen 3.503 N/A HIS 264.A ND1 ARG 210.A O no hydrogen 2.977 N/A GLU 269.A N GLN 265.A O no hydrogen 2.973 N/A PHE 270.A N LEU 266.A O no hydrogen 2.816 N/A GLN 271.A N PRO 267.A O no hydrogen 2.946 N/A LEU 272.A N ALA 268.A O no hydrogen 3.245 N/A LEU 273.A N GLU 269.A O no hydrogen 2.972 N/A TYR 274.A N PHE 270.A O no hydrogen 2.796 N/A ARG 275.A N GLN 271.A O no hydrogen 2.904 N/A MET 276.A N LEU 272.A O no hydrogen 2.899 N/A HIS 277.A N LEU 273.A O no hydrogen 2.834 N/A GLY 278.A N TYR 274.A O no hydrogen 3.057 N/A GLU 279.A N ARG 275.A O no hydrogen 2.979 N/A GLY 280.A N HIS 277.A O no hydrogen 2.968 N/A LEU 281.A N MET 276.A O no hydrogen 2.969 N/A THR 282.A OG1 ILE 228.A O no hydrogen 2.767 N/A LYS 283.A N ILE 228.A O no hydrogen 3.182 N/A LEU 284.A N HIS 277.A ND1 no hydrogen 2.965 N/A THR 285.A N LEU 230.A O no hydrogen 3.017 N/A SER 287.A OG HIS 288.A O no hydrogen 3.518 N/A CYS 289.A N SER 86.A O no hydrogen 2.828 N/A