Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5bo9_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 4.A N GLY 276.A O no hydrogen 2.903 N/A ALA 7.A N ASN 4.A OD1 no hydrogen 2.938 N/A PHE 8.A N ASN 4.A O no hydrogen 3.035 N/A LEU 9.A N ARG 5.A O no hydrogen 2.763 N/A HIS 10.A N THR 6.A O no hydrogen 2.978 N/A GLN 11.A N ALA 7.A O no hydrogen 2.954 N/A GLN 11.A NE2 TYR 199.A OH no hydrogen 3.047 N/A ARG 12.A N PHE 8.A O no hydrogen 2.963 N/A ARG 12.A NE SER 221.A O no hydrogen 2.804 N/A ARG 12.A NH2 CYS 224.A O no hydrogen 2.709 N/A ARG 12.A NH2 GLU 225.A OE1 no hydrogen 3.089 N/A GLN 13.A N LEU 9.A O no hydrogen 3.067 N/A GLU 14.A N HIS 10.A O no hydrogen 2.983 N/A ILE 15.A N GLN 11.A O no hydrogen 2.795 N/A LEU 16.A N ARG 12.A O no hydrogen 2.863 N/A GLN 17.A N GLN 13.A O no hydrogen 3.055 N/A GLN 17.A N GLU 14.A O no hydrogen 3.261 N/A HIS 18.A N ILE 15.A O no hydrogen 2.930 N/A HIS 18.A ND1 GLU 14.A O no hydrogen 3.018 N/A VAL 19.A N ILE 15.A O no hydrogen 2.833 N/A LYS 23.A N ASP 20.A OD1 no hydrogen 3.365 N/A ASN 24.A N ASP 20.A O no hydrogen 2.741 N/A PHE 25.A N VAL 21.A O no hydrogen 2.870 N/A SER 26.A N LYS 23.A O no hydrogen 3.342 N/A SER 26.A OG LEU 27.A O no hydrogen 2.690 N/A LEU 27.A N TRP 188.A O no hydrogen 2.865 N/A THR 28.A N SER 31.A OG no hydrogen 3.196 N/A LYS 29.A N PRO 60.A O no hydrogen 3.035 N/A LYS 29.A NZ LEU 59.A O no hydrogen 2.769 N/A LYS 29.A NZ ASP 61.A OD1 no hydrogen 2.952 N/A SER 31.A N THR 28.A O no hydrogen 2.947 N/A SER 31.A OG THR 28.A O no hydrogen 3.204 N/A VAL 32.A N LYS 29.A O no hydrogen 3.479 N/A ARG 33.A N GLN 36.A OE1 no hydrogen 2.825 N/A GLY 35.A N ILE 51.A O no hydrogen 2.756 N/A GLN 36.A N ARG 33.A O no hydrogen 3.245 N/A MET 38.A N PHE 49.A O no hydrogen 2.818 N/A ASP 41.A N PHE 159.A O no hydrogen 2.911 N/A TYR 42.A N PHE 160.A O no hydrogen 2.705 N/A SER 43.A N TYR 40.A O no hydrogen 3.490 N/A SER 43.A OG HIS 162.A ND1 no hydrogen 2.964 N/A TYR 47.A N SER 44.A O no hydrogen 3.213 N/A PHE 49.A N MET 38.A O no hydrogen 2.944 N/A SER 50.A OG GLY 35.A O no hydrogen 3.113 N/A ILE 51.A N GLN 36.A O no hydrogen 2.911 N/A PHE 55.A N SER 52.A OG no hydrogen 2.887 N/A ARG 56.A N SER 52.A O no hydrogen 3.075 N/A ARG 56.A NE LYS 29.A O no hydrogen 3.086 N/A ARG 56.A NE VAL 32.A O no hydrogen 3.280 N/A SER 57.A N ASN 53.A O no hydrogen 3.028 N/A SER 57.A OG ASN 54.A O no hydrogen 2.746 N/A LEU 58.A N PHE 55.A O no hydrogen 2.935 N/A LEU 59.A N ARG 56.A O no hydrogen 3.046 N/A SER 63.A OG ILE 22.A O no hydrogen 2.746 N/A ILE 65.A N SER 63.A OG no hydrogen 3.325 N/A MET 66.A N SER 63.A O no hydrogen 3.180 N/A LYS 68.A N ILE 65.A O no hydrogen 3.158 N/A TYR 70.A N ILE 223.A O no hydrogen 2.769 N/A ILE 72.A N ASP 95.A OD2 no hydrogen 2.994 N/A CYS 73.A N GLU 226.A O no hydrogen 2.870 N/A ALA 74.A N PHE 96.A O no hydrogen 2.974 N/A VAL 75.A N HIS 228.A O no hydrogen 2.943 N/A VAL 76.A N PHE 98.A O no hydrogen 2.885 N/A GLY 77.A N TYR 230.A O no hydrogen 2.752 N/A ASN 78.A ND2 CYS 100.A O no hydrogen 3.186 N/A SER 79.A N GLY 231.A O no hydrogen 3.008 N/A SER 79.A OG TRP 233.A O no hydrogen 2.796 N/A ILE 81.A N SER 79.A OG no hydrogen 3.030 N/A LEU 82.A N SER 79.A O no hydrogen 3.208 N/A THR 83.A N GLY 80.A O no hydrogen 3.150 N/A THR 83.A OG1 GLY 80.A O no hydrogen 3.355 N/A GLY 84.A N ASP 111.A OD2 no hydrogen 2.803 N/A SER 85.A N LEU 82.A O no hydrogen 2.895 N/A SER 85.A OG LEU 82.A O no hydrogen 2.508 N/A GLN 86.A N ASP 111.A OD1 no hydrogen 2.977 N/A CYS 87.A SG SER 85.A O no hydrogen 3.849 N/A CYS 87.A SG SER 85.A OG no hydrogen 3.475 N/A CYS 87.A SG SER 283.A O no hydrogen 4.040 N/A GLY 88.A N ARG 110.A O no hydrogen 2.938 N/A ILE 91.A N CYS 87.A O no hydrogen 2.909 N/A ASP 92.A N GLY 88.A O no hydrogen 2.908 N/A LYS 93.A N GLN 89.A O no hydrogen 3.090 N/A SER 94.A N ILE 91.A O no hydrogen 3.075 N/A SER 94.A OG ILE 91.A O no hydrogen 2.827 N/A ASP 95.A N ILE 72.A O no hydrogen 2.795 N/A PHE 96.A N ILE 72.A O no hydrogen 3.329 N/A VAL 97.A N ASN 117.A OD1 no hydrogen 2.851 N/A PHE 98.A N ALA 74.A O no hydrogen 2.928 N/A ARG 99.A N LEU 118.A O no hydrogen 2.770 N/A ARG 99.A NE LYS 115.A O no hydrogen 2.990 N/A ARG 99.A NE THR 116.A OG1 no hydrogen 2.935 N/A ARG 99.A NH1 VAL 112.A O no hydrogen 2.864 N/A ARG 99.A NH1 LYS 115.A O no hydrogen 2.665 N/A ARG 99.A NH2 VAL 112.A O no hydrogen 2.840 N/A CYS 100.A SG VAL 76.A O no hydrogen 3.457 N/A ASN 101.A N THR 120.A OG1 no hydrogen 2.726 N/A PHE 102.A N THR 119.A OG1 no hydrogen 3.147 N/A ALA 103.A N CYS 100.A O no hydrogen 3.285 N/A PHE 108.A N THR 105.A O no hydrogen 2.877 N/A GLN 109.A N GLU 106.A O no hydrogen 3.439 N/A ASP 111.A N PHE 108.A O no hydrogen 2.960 N/A VAL 112.A N PHE 108.A O no hydrogen 2.998 N/A GLY 113.A N GLN 109.A O no hydrogen 2.961 N/A ARG 114.A N ASP 92.A OD2 no hydrogen 3.029 N/A LYS 115.A N ASP 92.A OD1 no hydrogen 2.866 N/A LYS 115.A NZ ASP 92.A O no hydrogen 2.838 N/A LYS 115.A NZ SER 94.A O no hydrogen 2.848 N/A ASN 117.A N VAL 97.A O no hydrogen 3.027 N/A LEU 118.A N VAL 97.A O no hydrogen 3.183 N/A THR 119.A N ILE 153.A O no hydrogen 2.896 N/A THR 120.A N ARG 99.A O no hydrogen 3.100 N/A THR 120.A OG1 ASN 101.A OD1 no hydrogen 3.490 N/A PHE 121.A N TRP 155.A O no hydrogen 2.796 N/A ASN 122.A N ASN 101.A OD1 no hydrogen 2.946 N/A ILE 125.A N ASN 122.A O no hydrogen 2.885 N/A LEU 126.A N PRO 123.A O no hydrogen 3.060 N/A LYS 128.A N SER 124.A O no hydrogen 2.885 N/A TYR 129.A N ILE 125.A O no hydrogen 2.893 N/A TYR 130.A N LEU 126.A O no hydrogen 3.174 N/A TYR 130.A OH SER 145.A OG no hydrogen 3.030 N/A ASN 131.A ND2 ASP 138.A OD2 no hydrogen 3.177 N/A ASN 132.A N LEU 126.A O no hydrogen 2.945 N/A ASN 132.A ND2 THR 170.A OG1 no hydrogen 3.391 N/A LEU 133.A N TYR 130.A O no hydrogen 2.817 N/A LEU 134.A N ASN 131.A O no hydrogen 3.184 N/A THR 135.A OG1 GLN 137.A OE1 no hydrogen 3.300 N/A THR 135.A OG1 ASP 138.A OD2 no hydrogen 2.434 N/A ASP 138.A N THR 135.A OG1 no hydrogen 2.995 N/A ARG 139.A N THR 135.A O no hydrogen 2.985 N/A ARG 139.A NH1 GLU 177.A OE1 no hydrogen 2.979 N/A ARG 139.A NH1 GLU 177.A OE2 no hydrogen 3.528 N/A ARG 139.A NH2 GLU 177.A OE2 no hydrogen 2.727 N/A ASN 140.A N ILE 136.A O no hydrogen 2.814 N/A ASN 141.A N GLN 137.A O no hydrogen 2.874 N/A PHE 142.A N ASP 138.A O no hydrogen 2.956 N/A PHE 143.A N ARG 139.A O no hydrogen 2.902 N/A LEU 144.A N ASN 140.A O no hydrogen 3.002 N/A SER 145.A N ASN 141.A O no hydrogen 3.159 N/A SER 145.A OG TYR 130.A OH no hydrogen 3.030 N/A SER 145.A OG ASN 141.A O no hydrogen 3.163 N/A LEU 146.A N PHE 142.A O no hydrogen 3.001 N/A LYS 147.A N PHE 143.A O no hydrogen 2.981 N/A LYS 148.A N LEU 144.A O no hydrogen 3.033 N/A LYS 148.A NZ GLU 106.A OE1 no hydrogen 3.061 N/A LYS 148.A NZ GLU 106.A OE2 no hydrogen 3.442 N/A LEU 149.A N LEU 146.A O no hydrogen 3.009 N/A ASP 150.A N LYS 147.A O no hydrogen 2.935 N/A ALA 152.A N LEU 149.A O no hydrogen 2.957 N/A ILE 153.A N ASN 117.A O no hydrogen 3.026 N/A LEU 154.A N GLN 185.A O no hydrogen 2.873 N/A TRP 155.A N THR 119.A O no hydrogen 2.937 N/A TRP 155.A NE1 PHE 25.A O no hydrogen 2.846 N/A ILE 156.A N ALA 187.A O no hydrogen 3.004 N/A HIS 162.A N SER 43.A OG no hydrogen 3.162 N/A HIS 162.A ND1 SER 43.A OG no hydrogen 2.964 N/A SER 164.A N PHE 161.A O no hydrogen 3.037 N/A SER 164.A OG PHE 161.A O no hydrogen 3.345 N/A ALA 165.A N HIS 162.A O no hydrogen 3.124 N/A THR 168.A N SER 164.A O no hydrogen 2.875 N/A THR 168.A OG1 SER 164.A O no hydrogen 2.828 N/A ARG 169.A N ALA 165.A O no hydrogen 3.310 N/A THR 170.A N THR 166.A O no hydrogen 3.176 N/A THR 170.A OG1 THR 166.A O no hydrogen 3.122 N/A LEU 171.A N VAL 167.A O no hydrogen 2.855 N/A VAL 172.A N THR 168.A O no hydrogen 2.821 N/A ASP 173.A N ARG 169.A O no hydrogen 3.042 N/A PHE 174.A N THR 170.A O no hydrogen 3.064 N/A PHE 175.A N LEU 171.A O no hydrogen 2.916 N/A VAL 176.A N VAL 172.A O no hydrogen 2.793 N/A GLU 177.A N ASP 173.A O no hydrogen 2.965 N/A HIS 178.A N PHE 174.A O no hydrogen 2.930 N/A HIS 178.A ND1 PHE 174.A O no hydrogen 2.799 N/A ARG 179.A N VAL 176.A O no hydrogen 3.089 N/A ARG 179.A NH2 SER 57.A OG no hydrogen 2.656 N/A GLN 181.A N HIS 178.A O no hydrogen 2.981 N/A GLN 185.A N ALA 152.A O no hydrogen 2.837 N/A GLN 185.A NE2 GLY 151.A O no hydrogen 3.031 N/A ALA 187.A N LEU 154.A O no hydrogen 2.904 N/A TRP 188.A N SER 26.A OG no hydrogen 2.876 N/A ASN 191.A ND2 HIS 39.A O no hydrogen 2.897 N/A ASN 191.A ND2 ASP 41.A OD1 no hydrogen 2.887 N/A MET 193.A N ASP 41.A OD2 no hydrogen 2.852 N/A HIS 195.A N ILE 192.A O no hydrogen 2.945 N/A VAL 196.A N ILE 192.A O no hydrogen 3.083 N/A ASN 197.A N MET 193.A O no hydrogen 2.808 N/A ARG 198.A N HIS 195.A O no hydrogen 3.109 N/A TRP 200.A NE1 THR 218.A OG1 no hydrogen 2.858 N/A LYS 201.A N ASN 197.A O no hydrogen 2.791 N/A ASN 202.A N TYR 199.A O no hydrogen 3.210 N/A LYS 203.A N TRP 200.A O no hydrogen 3.202 N/A LYS 203.A NZ GLU 14.A OE1 no hydrogen 2.753 N/A HIS 204.A N LYS 201.A O no hydrogen 3.066 N/A LEU 205.A N TRP 200.A O no hydrogen 3.075 N/A ARG 209.A N SER 259.A O no hydrogen 3.071 N/A SER 211.A N GLU 265.A OE2 no hydrogen 2.796 N/A SER 211.A OG GLU 265.A OE1 no hydrogen 2.429 N/A SER 211.A OG GLU 265.A OE2 no hydrogen 3.478 N/A LEU 215.A N SER 211.A O no hydrogen 3.036 N/A MET 216.A N THR 212.A O no hydrogen 2.823 N/A TYR 217.A N GLY 213.A O no hydrogen 2.932 N/A TYR 217.A OH GLN 11.A OE1 no hydrogen 2.559 N/A THR 218.A N ILE 214.A O no hydrogen 2.927 N/A THR 218.A OG1 ILE 214.A O no hydrogen 2.774 N/A LEU 219.A N LEU 215.A O no hydrogen 3.183 N/A ALA 220.A N MET 216.A O no hydrogen 2.792 N/A SER 221.A N TYR 217.A O no hydrogen 3.022 N/A SER 221.A OG THR 218.A O no hydrogen 2.718 N/A ALA 222.A N LEU 219.A O no hydrogen 3.136 N/A ILE 223.A N ALA 220.A O no hydrogen 3.027 N/A CYS 224.A N ALA 220.A O no hydrogen 2.808 N/A CYS 224.A SG ALA 220.A O no hydrogen 3.266 N/A GLU 225.A N TYR 70.A O no hydrogen 2.957 N/A GLU 225.A N ASN 71.A O no hydrogen 3.156 N/A GLU 226.A N ASN 71.A O no hydrogen 2.999 N/A HIS 228.A N CYS 73.A O no hydrogen 2.844 N/A HIS 228.A NE2 GLU 226.A OE2 no hydrogen 2.878 N/A LEU 229.A N LYS 279.A O no hydrogen 2.655 N/A TYR 230.A N VAL 75.A O no hydrogen 2.983 N/A TYR 230.A OH GLU 90.A OE1 no hydrogen 2.499 N/A TRP 233.A NE1 PHE 237.A O no hydrogen 2.831 N/A ASP 238.A N GLU 243.A O no hydrogen 3.004 N/A ASN 240.A N ASP 238.A OD2 no hydrogen 2.857 N/A THR 241.A N ASP 238.A OD2 no hydrogen 2.931 N/A THR 241.A OG1 GLU 243.A OE1 no hydrogen 2.356 N/A ARG 242.A N ASP 238.A O no hydrogen 2.822 N/A ARG 242.A NE PRO 239.A O no hydrogen 3.491 N/A GLU 243.A N THR 241.A OG1 no hydrogen 3.333 N/A LEU 245.A N GLY 236.A O no hydrogen 2.821 N/A TYR 249.A N ASN 78.A O no hydrogen 2.873 N/A TYR 249.A OH PRO 104.A O no hydrogen 2.644 N/A ASP 251.A N HIS 248.A O no hydrogen 3.213 N/A THR 255.A N LYS 252.A O no hydrogen 3.062 N/A THR 255.A OG1 LYS 252.A O no hydrogen 2.522 N/A HIS 260.A ND1 ARG 209.A O no hydrogen 2.553 N/A GLU 265.A N GLN 261.A O no hydrogen 3.145 N/A PHE 266.A N LEU 262.A O no hydrogen 2.763 N/A GLN 267.A N PRO 263.A O no hydrogen 2.839 N/A LEU 268.A N ALA 264.A O no hydrogen 3.084 N/A LEU 269.A N GLU 265.A O no hydrogen 2.935 N/A TYR 270.A N PHE 266.A O no hydrogen 2.862 N/A ARG 271.A N GLN 267.A O no hydrogen 2.962 N/A ARG 271.A NE GLU 275.A OE1 no hydrogen 3.047 N/A MET 272.A N LEU 268.A O no hydrogen 2.980 N/A HIS 273.A N LEU 269.A O no hydrogen 2.845 N/A GLY 274.A N TYR 270.A O no hydrogen 2.932 N/A GLU 275.A N ARG 271.A O no hydrogen 3.078 N/A GLY 276.A N HIS 273.A O no hydrogen 2.998 N/A LEU 277.A N MET 272.A O no hydrogen 3.002 N/A THR 278.A OG1 ILE 227.A O no hydrogen 2.941 N/A LYS 279.A N ILE 227.A O no hydrogen 3.269 N/A LEU 280.A N HIS 273.A ND1 no hydrogen 2.990 N/A THR 281.A N LEU 229.A O no hydrogen 3.059 N/A SER 283.A OG HIS 284.A O no hydrogen 3.414 N/A CYS 285.A N SER 85.A O no hydrogen 2.803 N/A CYS 285.A SG GLU 90.A OE1 no hydrogen 3.789 N/A CYS 285.A SG GLU 90.A OE2 no hydrogen 3.881 N/A