Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5c0j_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 1.A N HIS 4.A NE2 no hydrogen 3.517 N/A HIS 4.A N VAL 104.A O no hydrogen 3.011 N/A HIS 4.A ND1 ASP 30.A OD2 no hydrogen 2.719 N/A SER 5.A N ASP 30.A OD1 no hydrogen 2.826 N/A MET 6.A N CYS 102.A O no hydrogen 2.959 N/A ARG 7.A N TYR 28.A O no hydrogen 2.930 N/A ARG 7.A NE TYR 114.A OH no hydrogen 2.524 N/A ARG 7.A NH1 ASP 103.A OD1 no hydrogen 3.122 N/A TYR 8.A N TYR 100.A O no hydrogen 2.893 N/A PHE 9.A N VAL 26.A O no hydrogen 2.901 N/A PHE 10.A N ARG 98.A O no hydrogen 2.860 N/A THR 11.A N ILE 24.A O no hydrogen 2.841 N/A SER 12.A N VAL 96.A O.A no hydrogen 2.898 N/A SER 12.A N VAL 96.A O.B no hydrogen 2.818 N/A SER 12.A OG HIS 75.A ND1 no hydrogen 2.684 N/A VAL 13.A N ARG 22.A O no hydrogen 2.890 N/A SER 14.A N HIS 94.A O no hydrogen 2.858 N/A SER 14.A OG HIS 94.A O no hydrogen 3.442 N/A ARG 15.A NH1.B ASP 40.A OD1 no hydrogen 3.153 N/A ARG 15.A NH1.B ASP 40.A OD2 no hydrogen 3.333 N/A ARG 15.A NH2.B ASP 40.A OD2 no hydrogen 2.973 N/A ARG 18.A N ARG 15.A O.A no hydrogen 3.256 N/A ARG 18.A N ARG 15.A O.B no hydrogen 3.219 N/A ARG 22.A N VAL 13.A O no hydrogen 2.891 N/A ARG 22.A NE ASP 38.A OD1 no hydrogen 2.774 N/A ARG 22.A NH2 ASP 38.A OD1 no hydrogen 3.330 N/A ARG 22.A NH2 ASP 38.A OD2 no hydrogen 2.879 N/A PHE 23.A N SER 39.A OG no hydrogen 2.879 N/A ILE 24.A N THR 11.A O no hydrogen 2.888 N/A ALA 25.A N PHE 37.A O no hydrogen 2.824 N/A VAL 26.A N PHE 9.A O no hydrogen 2.871 N/A GLY 27.A N VAL 35.A O no hydrogen 3.002 N/A TYR 28.A N ARG 7.A O no hydrogen 2.807 N/A VAL 29.A N THR 32.A O no hydrogen 2.996 N/A ASP 30.A N SER 5.A O no hydrogen 2.748 N/A THR 32.A N VAL 29.A O no hydrogen 2.877 N/A THR 32.A OG1 TYR 210.A OH no hydrogen 2.889 N/A GLN 33.A NE2 VAL 35.A O no hydrogen 3.176 N/A PHE 34.A N GLY 27.A O no hydrogen 2.783 N/A ARG 36.A N.A GLU 47.A O no hydrogen 2.939 N/A ARG 36.A N.B GLU 47.A O no hydrogen 2.954 N/A ARG 36.A NE.A GLU 47.A OE2 no hydrogen 3.345 N/A ARG 36.A NH1.A GLU 47.A OE2 no hydrogen 3.502 N/A ARG 36.A NH1.B GLU 47.A OE1 no hydrogen 3.192 N/A PHE 37.A N ALA 25.A O no hydrogen 2.811 N/A SER 39.A N PHE 23.A O no hydrogen 2.841 N/A SER 39.A OG PHE 23.A O no hydrogen 3.484 N/A ASP 40.A N ASP 38.A OD1 no hydrogen 2.900 N/A ALA 41.A N ASP 38.A O no hydrogen 2.984 N/A SER 43.A OG ARG 45.A O no hydrogen 3.407 N/A SER 43.A OG GLU 47.A OE1 no hydrogen 3.040 N/A GLN 44.A NE2 SER 39.A O no hydrogen 2.868 N/A GLN 44.A NE2 ALA 41.A O no hydrogen 2.924 N/A ARG 45.A N SER 43.A OG no hydrogen 3.083 N/A ARG 45.A NH1 ASP 62.A OD1 no hydrogen 3.041 N/A ARG 45.A NH2 ASP 62.A OD1 no hydrogen 2.857 N/A MET 46.A N THR 65.A OG1 no hydrogen 3.039 N/A GLU 47.A N ARG 36.A O.A no hydrogen 2.851 N/A GLU 47.A N ARG 36.A O.B no hydrogen 2.871 N/A ARG 49.A N.A PHE 34.A O no hydrogen 2.866 N/A ARG 49.A N.B PHE 34.A O no hydrogen 2.868 N/A ARG 49.A NH1.B GLU 47.A OE2 no hydrogen 3.520 N/A ARG 49.A NH1.B PRO 48.A O no hydrogen 2.758 N/A ARG 49.A NH2.B GLU 47.A OE2 no hydrogen 3.240 N/A ILE 53.A N ALA 50.A O no hydrogen 3.261 N/A GLU 54.A N PRO 51.A O no hydrogen 3.217 N/A GLU 56.A N ILE 53.A O no hydrogen 3.003 N/A TYR 60.A OH TYR 172.A OH no hydrogen 2.696 N/A TRP 61.A N GLY 57.A O no hydrogen 3.274 N/A TRP 61.A NE1 GLU 56.A O no hydrogen 3.043 N/A ASP 62.A N PRO 58.A O no hydrogen 2.908 N/A GLY 63.A N GLU 59.A O no hydrogen 3.006 N/A GLU 64.A N TYR 60.A O no hydrogen 2.856 N/A THR 65.A N TRP 61.A O no hydrogen 2.885 N/A THR 65.A OG1 TRP 61.A O no hydrogen 2.781 N/A ARG 66.A N.A ASP 62.A O no hydrogen 2.985 N/A ARG 66.A N.B ASP 62.A O no hydrogen 2.991 N/A LYS 67.A N GLY 63.A O no hydrogen 2.903 N/A LYS 67.A NZ GLU 64.A OE2 no hydrogen 2.770 N/A VAL 68.A N.A GLU 64.A O no hydrogen 2.939 N/A VAL 68.A N.B GLU 64.A O no hydrogen 2.981 N/A LYS 69.A N THR 65.A O no hydrogen 2.927 N/A ALA 70.A N ARG 66.A O.A no hydrogen 3.017 N/A ALA 70.A N ARG 66.A O.B no hydrogen 3.032 N/A HIS 71.A N LYS 67.A O no hydrogen 2.921 N/A SER 72.A N VAL 68.A O.A no hydrogen 2.953 N/A SER 72.A N VAL 68.A O.B no hydrogen 2.796 N/A SER 72.A OG LYS 69.A O no hydrogen 2.615 N/A GLN 73.A N LYS 69.A O no hydrogen 3.050 N/A THR 74.A N ALA 70.A O no hydrogen 3.028 N/A THR 74.A OG1 ALA 70.A O no hydrogen 3.406 N/A HIS 75.A N HIS 71.A O no hydrogen 2.987 N/A HIS 75.A ND1 SER 12.A OG no hydrogen 2.684 N/A ARG 76.A N SER 72.A O no hydrogen 2.910 N/A ARG 76.A NE GLN 73.A OE1 no hydrogen 2.761 N/A ARG 76.A NH2 GLN 73.A OE1 no hydrogen 3.274 N/A VAL 77.A N GLN 73.A O no hydrogen 3.079 N/A ASP 78.A N THR 74.A O no hydrogen 2.867 N/A LEU 79.A N HIS 75.A O no hydrogen 2.879 N/A GLY 80.A N ARG 76.A O no hydrogen 3.427 N/A THR 81.A N VAL 77.A O no hydrogen 2.927 N/A THR 81.A OG1 VAL 77.A O no hydrogen 3.143 N/A LEU 82.A N ASP 78.A O no hydrogen 2.766 N/A ARG 83.A N.A LEU 79.A O no hydrogen 3.097 N/A ARG 83.A N.B LEU 79.A O no hydrogen 3.114 N/A ARG 83.A NH1.B GLN 88.A O no hydrogen 2.930 N/A GLY 84.A N GLY 80.A O no hydrogen 3.202 N/A TYR 85.A N THR 81.A O no hydrogen 2.828 N/A TYR 86.A N LEU 82.A O no hydrogen 2.882 N/A TYR 86.A OH ASP 138.A OD2 no hydrogen 2.510 N/A ASN 87.A N GLY 84.A O no hydrogen 3.072 N/A GLN 88.A N ARG 83.A O.A no hydrogen 2.972 N/A GLN 88.A N ARG 83.A O.B no hydrogen 2.951 N/A ALA 91.A N SER 89.A OG no hydrogen 2.818 N/A SER 93.A OG SER 14.A O no hydrogen 2.775 N/A HIS 94.A N SER 14.A OG no hydrogen 2.912 N/A HIS 94.A ND1 ASP 120.A OD2 no hydrogen 2.699 N/A THR 95.A N ASP 120.A OD1 no hydrogen 2.866 N/A VAL 96.A N.A SER 12.A O no hydrogen 2.894 N/A VAL 96.A N.B SER 12.A O no hydrogen 2.918 N/A GLN 97.A N ALA 118.A O no hydrogen 2.999 N/A ARG 98.A N PHE 10.A O no hydrogen 2.901 N/A ARG 98.A NE HIS 75.A NE2 no hydrogen 3.355 N/A ARG 98.A NH1 HIS 115.A NE2 no hydrogen 3.051 N/A ARG 98.A NH2 HIS 75.A NE2 no hydrogen 3.395 N/A MET 99.A N GLN 116.A O no hydrogen 2.897 N/A TYR 100.A N TYR 8.A O no hydrogen 3.002 N/A GLY 101.A N TYR 114.A O no hydrogen 3.066 N/A CYS 102.A N MET 6.A O no hydrogen 2.995 N/A ASP 103.A N ARG 112.A O no hydrogen 2.777 N/A VAL 104.A N HIS 4.A O no hydrogen 2.834 N/A GLY 105.A N ARG 109.A O no hydrogen 2.991 N/A TRP 108.A N GLY 105.A O no hydrogen 2.888 N/A ARG 109.A N ASP 107.A OD1 no hydrogen 3.007 N/A ARG 109.A NE ASP 107.A OD2 no hydrogen 2.975 N/A LEU 111.A N ASP 103.A O no hydrogen 2.828 N/A ARG 112.A N ASP 103.A O no hydrogen 3.404 N/A ARG 112.A NH1 ASP 103.A OD2 no hydrogen 2.728 N/A TYR 114.A N GLY 101.A O no hydrogen 2.945 N/A TYR 114.A OH ASP 103.A OD1 no hydrogen 2.804 N/A GLN 116.A N MET 99.A O no hydrogen 2.807 N/A TYR 117.A N ILE 125.A O no hydrogen 2.862 N/A TYR 117.A OH ASP 78.A OD2 no hydrogen 2.686 N/A ALA 118.A N GLN 97.A O no hydrogen 2.815 N/A TYR 119.A N LYS 122.A O.A no hydrogen 3.008 N/A TYR 119.A N LYS 122.A O.B no hydrogen 3.009 N/A TYR 119.A OH GLN 88.A OE1 no hydrogen 2.534 N/A ASP 120.A N THR 95.A O no hydrogen 2.791 N/A LYS 122.A N.A TYR 119.A O no hydrogen 3.111 N/A LYS 122.A N.B TYR 119.A O no hydrogen 3.084 N/A TYR 124.A N TYR 117.A O no hydrogen 2.904 N/A TYR 124.A OH THR 144.A OG1 no hydrogen 2.738 N/A ILE 125.A N TYR 117.A O no hydrogen 3.251 N/A ALA 126.A N THR 135.A O no hydrogen 2.934 N/A LEU 127.A N HIS 115.A O no hydrogen 2.871 N/A LYS 128.A N SER 133.A O no hydrogen 2.844 N/A LEU 131.A N LYS 128.A O no hydrogen 2.855 N/A ARG 132.A N ASP 130.A OD1 no hydrogen 2.818 N/A ARG 132.A NH1 ASP 130.A O no hydrogen 2.797 N/A SER 133.A OG ASP 130.A OD1 no hydrogen 2.931 N/A SER 133.A OG ASP 130.A OD2 no hydrogen 3.269 N/A THR 135.A N ALA 126.A O no hydrogen 2.826 N/A ALA 137.A N TYR 124.A O no hydrogen 2.938 N/A ALA 141.A N ASP 138.A OD1 no hydrogen 2.967 N/A GLN 142.A N ASP 138.A O no hydrogen 2.851 N/A THR 143.A N MET 139.A O no hydrogen 3.229 N/A THR 143.A OG1 MET 139.A O no hydrogen 3.160 N/A THR 144.A N ALA 140.A O no hydrogen 3.272 N/A THR 144.A OG1 TYR 124.A OH no hydrogen 2.738 N/A LYS 145.A N ALA 141.A O no hydrogen 2.839 N/A LYS 145.A NZ TRP 134.A O no hydrogen 2.916 N/A HIS 146.A N GLN 142.A O no hydrogen 2.962 N/A LYS 147.A N THR 143.A O no hydrogen 3.048 N/A LYS 147.A NZ TYR 85.A OH no hydrogen 2.704 N/A TRP 148.A N THR 144.A O no hydrogen 2.757 N/A GLU 149.A N LYS 145.A O no hydrogen 2.832 N/A ALA 150.A N HIS 146.A O no hydrogen 3.109 N/A ALA 151.A N LYS 147.A O no hydrogen 3.110 N/A HIS 152.A N GLU 149.A O no hydrogen 3.181 N/A VAL 153.A N TRP 148.A O no hydrogen 3.023 N/A GLN 156.A N HIS 152.A O no hydrogen 3.455 N/A LEU 157.A N.A VAL 153.A O no hydrogen 2.960 N/A LEU 157.A N.B VAL 153.A O no hydrogen 2.968 N/A ARG 158.A N ALA 154.A O no hydrogen 2.715 N/A ARG 158.A NH2 LEU 131.A O no hydrogen 2.898 N/A ARG 158.A NH2 GLU 155.A OE1.A no hydrogen 3.006 N/A ALA 159.A N GLU 155.A O.A no hydrogen 3.107 N/A ALA 159.A N GLU 155.A O.B no hydrogen 3.106 N/A TYR 160.A N GLN 156.A O no hydrogen 3.218 N/A LEU 161.A N LEU 157.A O.A no hydrogen 2.751 N/A LEU 161.A N LEU 157.A O.B no hydrogen 2.714 N/A GLU 162.A N ARG 158.A O no hydrogen 2.996 N/A GLY 163.A N TYR 160.A O no hydrogen 3.329 N/A CYS 165.A N TYR 160.A O no hydrogen 2.854 N/A GLU 167.A N.A GLY 163.A O no hydrogen 2.974 N/A GLU 167.A N.B GLY 163.A O no hydrogen 2.987 N/A TRP 168.A N THR 164.A O no hydrogen 2.927 N/A LEU 169.A N CYS 165.A O no hydrogen 2.942 N/A ARG 170.A N VAL 166.A O no hydrogen 2.995 N/A ARG 170.A NH1 TRP 108.A O no hydrogen 3.169 N/A ARG 171.A N GLU 167.A O.A no hydrogen 3.134 N/A ARG 171.A N GLU 167.A O.B no hydrogen 3.140 N/A ARG 171.A NE GLU 56.A OE2 no hydrogen 2.909 N/A ARG 171.A NH2 GLU 56.A OE1 no hydrogen 2.870 N/A TYR 172.A N TRP 168.A O no hydrogen 2.874 N/A TYR 172.A OH TYR 60.A OH no hydrogen 2.696 N/A LEU 173.A N LEU 169.A O no hydrogen 2.865 N/A GLU 174.A N.A ARG 170.A O no hydrogen 3.168 N/A GLU 174.A N.B ARG 170.A O no hydrogen 3.094 N/A ASN 175.A N ARG 171.A O no hydrogen 2.851 N/A GLY 176.A N TYR 172.A O no hydrogen 2.771 N/A LYS 177.A N GLU 174.A O.A no hydrogen 3.300 N/A LYS 177.A N GLU 174.A O.B no hydrogen 3.092 N/A LYS 177.A NZ GLU 174.A OE2.A no hydrogen 2.805 N/A THR 179.A N GLY 176.A O no hydrogen 2.931 N/A THR 179.A OG1 GLY 176.A O no hydrogen 3.225 N/A LEU 180.A N GLY 176.A O no hydrogen 2.687 N/A GLN 181.A N LYS 177.A O no hydrogen 2.971 N/A ARG 182.A N THR 179.A O no hydrogen 3.197 N/A ARG 182.A NE ASP 184.A OD1 no hydrogen 2.759 N/A ARG 182.A NH1 ASP 184.A OD1 no hydrogen 3.531 N/A ARG 182.A NH1 ASP 184.A OD2 no hydrogen 3.182 N/A ASP 184.A N TYR 210.A O no hydrogen 2.881 N/A LYS 187.A N LEU 207.A O no hydrogen 2.865 N/A HIS 189.A N TRP 205.A O no hydrogen 3.277 N/A THR 191.A N ARG 203.A O no hydrogen 2.863 N/A HIS 193.A N.A THR 201.A O no hydrogen 2.907 N/A HIS 193.A N.B THR 201.A O no hydrogen 2.910 N/A VAL 195.A N GLU 199.A O no hydrogen 3.001 N/A SER 196.A N GLU 199.A O no hydrogen 3.232 N/A HIS 198.A N SER 196.A OG no hydrogen 2.948 N/A GLU 199.A N SER 196.A OG no hydrogen 3.088 N/A ALA 200.A N VAL 250.A O no hydrogen 2.917 N/A THR 201.A N HIS 193.A O.A no hydrogen 2.861 N/A THR 201.A N HIS 193.A O.B no hydrogen 2.749 N/A LEU 202.A N VAL 248.A O no hydrogen 2.882 N/A ARG 203.A N THR 191.A O no hydrogen 2.863 N/A CYS 204.A N.A ALA 246.A O no hydrogen 2.728 N/A CYS 204.A N.B ALA 246.A O no hydrogen 2.752 N/A CYS 204.A SG.B ALA 246.A O no hydrogen 3.636 N/A TRP 205.A N HIS 189.A O no hydrogen 2.854 N/A ALA 206.A N LYS 244.A O no hydrogen 2.836 N/A LEU 207.A N LYS 187.A O no hydrogen 2.884 N/A PHE 209.A N PHE 242.A O no hydrogen 3.197 N/A TYR 210.A N ASP 184.A O no hydrogen 2.963 N/A TYR 210.A OH THR 32.A OG1 no hydrogen 2.889 N/A ALA 212.A N ASP 31.A OD2 no hydrogen 2.846 N/A THR 215.A N GLN 263.A O no hydrogen 3.066 N/A THR 217.A N HIS 261.A O no hydrogen 2.949 N/A GLN 219.A N THR 259.A O no hydrogen 2.799 N/A ARG 220.A N GLU 223.A O no hydrogen 2.870 N/A ARG 220.A NH1 ASP 221.A OD2 no hydrogen 2.788 N/A ASP 221.A N ARG 257.A O no hydrogen 2.883 N/A GLU 223.A N ARG 220.A O no hydrogen 2.962 N/A GLN 225.A N TRP 218.A O no hydrogen 2.917 N/A GLN 225.A NE2 GLN 227.A O no hydrogen 2.914 N/A THR 229.A N THR 226.A O no hydrogen 3.342 N/A THR 229.A OG1 THR 226.A O no hydrogen 2.624 N/A GLU 230.A N ALA 247.A O no hydrogen 2.869 N/A VAL 232.A N TRP 245.A O no hydrogen 3.139 N/A ARG 235.A N GLN 243.A O no hydrogen 3.055 N/A ARG 235.A NE GLN 243.A OE1 no hydrogen 2.871 N/A ARG 235.A NH2 GLN 243.A OE1 no hydrogen 3.085 N/A ALA 237.A N THR 241.A O no hydrogen 2.818 N/A THR 241.A N ASP 239.A OD1 no hydrogen 3.032 N/A THR 241.A OG1 ASP 239.A OD1 no hydrogen 2.657 N/A PHE 242.A N PHE 209.A O no hydrogen 2.867 N/A GLN 243.A N ARG 235.A O no hydrogen 2.849 N/A LYS 244.A N ALA 206.A O no hydrogen 2.936 N/A LYS 244.A NZ VAL 232.A O no hydrogen 2.810 N/A LYS 244.A NZ THR 234.A OG1 no hydrogen 3.052 N/A ALA 246.A N CYS 204.A O.A no hydrogen 2.983 N/A ALA 246.A N CYS 204.A O.B no hydrogen 3.001 N/A ALA 247.A N GLU 230.A O no hydrogen 2.786 N/A VAL 248.A N LEU 202.A O no hydrogen 2.908 N/A VAL 249.A N ASP 228.A O no hydrogen 2.999 N/A VAL 250.A N ALA 200.A O no hydrogen 2.792 N/A SER 252.A N.A HIS 198.A O no hydrogen 2.850 N/A SER 252.A N.B HIS 198.A O no hydrogen 2.819 N/A GLY 253.A N GLU 255.A OE2 no hydrogen 2.797 N/A GLN 254.A N PRO 251.A O no hydrogen 2.964 N/A GLU 255.A N GLU 255.A OE2 no hydrogen 2.836 N/A GLN 256.A NE2 GLY 253.A O no hydrogen 2.935 N/A ARG 257.A N GLN 254.A O no hydrogen 3.014 N/A ARG 257.A NE GLN 254.A OE1 no hydrogen 2.962 N/A ARG 257.A NH1 GLN 254.A OE1 no hydrogen 3.344 N/A ARG 257.A NH2 ASP 221.A OD2 no hydrogen 2.818 N/A TYR 258.A N GLU 255.A O no hydrogen 3.084 N/A THR 259.A N GLN 219.A O no hydrogen 3.014 N/A THR 259.A OG1 HIS 261.A NE2 no hydrogen 2.770 N/A CYS 260.A N.A LEU 273.A O no hydrogen 2.874 N/A CYS 260.A N.B LEU 273.A O no hydrogen 2.906 N/A CYS 260.A SG.B THR 217.A O no hydrogen 3.878 N/A HIS 261.A N THR 217.A O no hydrogen 2.829 N/A HIS 261.A NE2 THR 259.A OG1 no hydrogen 2.770 N/A VAL 262.A N LEU 271.A O no hydrogen 2.919 N/A GLN 263.A N THR 215.A O no hydrogen 2.913 N/A HIS 264.A NE2 PRO 211.A O no hydrogen 2.855 N/A GLY 266.A N HIS 264.A ND1 no hydrogen 2.951 N/A LEU 267.A N HIS 264.A O no hydrogen 2.949 N/A LEU 271.A N VAL 262.A O no hydrogen 2.999 N/A LEU 273.A N CYS 260.A O.A no hydrogen 2.809 N/A LEU 273.A N CYS 260.A O.B no hydrogen 2.847 N/A ARG 274.A NH1 GLN 256.A O no hydrogen 2.738 N/A