Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5c7m_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 4.A N ASP 2.A OD1 no hydrogen 3.263 N/A LYS 6.A N ASP 2.A O no hydrogen 3.335 N/A VAL 7.A N PHE 3.A O no hydrogen 2.846 N/A GLN 8.A N LYS 4.A O no hydrogen 3.155 N/A TYR 9.A N ALA 5.A O no hydrogen 3.096 N/A PHE 10.A N LYS 6.A O no hydrogen 3.087 N/A ARG 11.A N VAL 7.A O no hydrogen 2.982 N/A PHE 12.A N GLN 8.A O no hydrogen 3.374 N/A TRP 13.A N TYR 9.A O no hydrogen 3.235 N/A CYS 14.A N PHE 10.A O no hydrogen 3.252 N/A CYS 14.A SG PHE 10.A O no hydrogen 3.423 N/A GLN 15.A N ARG 11.A O no hydrogen 3.237 N/A GLN 16.A N PHE 12.A O no hydrogen 3.368 N/A LEU 17.A N TRP 13.A O no hydrogen 3.331 N/A MET 19.A N ARG 49.A O no hydrogen 3.468 N/A ILE 23.A N ARG 51.A O no hydrogen 2.933 N/A ILE 25.A N TRP 53.A O no hydrogen 3.038 N/A THR 26.A N GLN 39.A OE1 no hydrogen 2.741 N/A VAL 27.A N ILE 55.A O no hydrogen 3.209 N/A THR 28.A OG1 ASP 35.A OD2 no hydrogen 2.688 N/A THR 31.A OG1 THR 28.A OG1 no hydrogen 3.124 N/A THR 31.A OG1 ASP 35.A OD1 no hydrogen 2.697 N/A THR 31.A OG1 ASP 35.A OD2 no hydrogen 2.930 N/A ASP 35.A N THR 31.A O no hydrogen 2.927 N/A SER 36.A N LEU 32.A O no hydrogen 2.839 N/A SER 36.A OG LEU 32.A O no hydrogen 2.701 N/A PHE 37.A N PHE 33.A O no hydrogen 3.002 N/A GLN 38.A N GLU 34.A O no hydrogen 2.909 N/A GLN 39.A N ASP 35.A O no hydrogen 2.806 N/A ILE 40.A N SER 36.A O no hydrogen 2.766 N/A MET 41.A N PHE 37.A O no hydrogen 3.102 N/A SER 42.A N GLN 38.A O no hydrogen 2.985 N/A SER 42.A OG GLN 39.A O no hydrogen 2.798 N/A SER 44.A OG ASP 47.A OD2 no hydrogen 2.831 N/A ASP 47.A N SER 44.A OG no hydrogen 3.225 N/A LEU 48.A N SER 44.A O no hydrogen 2.985 N/A ARG 49.A N GLN 46.A O no hydrogen 3.358 N/A ARG 49.A NH2 GLU 234.A O no hydrogen 3.480 N/A ARG 49.A NH2 ILE 235.A O no hydrogen 2.722 N/A ARG 50.A N ASP 47.A O no hydrogen 3.155 N/A ARG 50.A NE PRO 20.A O no hydrogen 3.017 N/A ARG 51.A N GLN 21.A O no hydrogen 3.293 N/A TRP 53.A N ILE 23.A O no hydrogen 3.002 N/A TRP 53.A NE1 TYR 64.A O no hydrogen 2.687 N/A TRP 53.A NE1 GLY 65.A O no hydrogen 3.048 N/A ILE 55.A N ILE 25.A O no hydrogen 2.886 N/A GLU 60.A N GLU 60.A OE1 no hydrogen 2.762 N/A LEU 62.A N GLU 59.A O no hydrogen 3.364 N/A GLY 65.A N ASP 63.A OD1 no hydrogen 2.830 N/A ARG 69.A NH2.A GLY 124.A O no hydrogen 3.415 N/A TRP 71.A N VAL 67.A O no hydrogen 3.151 N/A TRP 71.A NE1 SER 36.A OG no hydrogen 2.904 N/A PHE 72.A N ALA 68.A O no hydrogen 2.756 N/A PHE 73.A N ARG 69.A O.A no hydrogen 3.060 N/A PHE 73.A N ARG 69.A O.B no hydrogen 3.049 N/A LEU 74.A N GLU 70.A O no hydrogen 2.868 N/A LEU 75.A N TRP 71.A O no hydrogen 2.758 N/A SER 76.A N PHE 72.A O no hydrogen 3.359 N/A SER 76.A OG PHE 72.A O no hydrogen 3.377 N/A SER 76.A OG PHE 73.A O no hydrogen 2.730 N/A HIS 77.A N LEU 74.A O no hydrogen 3.187 N/A HIS 77.A NE2 ASP 128.A OD2 no hydrogen 2.735 N/A GLU 78.A N LEU 74.A O no hydrogen 3.369 N/A VAL 79.A N LEU 75.A O no hydrogen 3.011 N/A ASN 81.A N GLU 78.A O no hydrogen 3.226 N/A ASN 81.A ND2 GLU 78.A OE1 no hydrogen 3.360 N/A MET 83.A N ASN 81.A OD1 no hydrogen 3.266 N/A TYR 84.A OH GLU 78.A OE2 no hydrogen 2.892 N/A CYS 85.A N PRO 82.A O no hydrogen 2.969 N/A CYS 85.A SG MET 83.A O no hydrogen 3.578 N/A GLU 88.A N GLN 95.A O no hydrogen 3.007 N/A LEU 94.A N GLY 130.A O no hydrogen 2.744 N/A ASN 97.A N LEU 86.A O no hydrogen 2.884 N/A ASN 97.A ND2 GLU 88.A OE2 no hydrogen 3.010 N/A SER 100.A OG ASN 97.A O no hydrogen 3.378 N/A SER 100.A OG HIS 106.A ND1 no hydrogen 2.900 N/A ILE 102.A N ALA 99.A O no hydrogen 3.443 N/A ASN 103.A N SER 100.A O no hydrogen 2.985 N/A ASN 103.A ND2 TYR 84.A O no hydrogen 3.287 N/A HIS 106.A N ASN 103.A O no hydrogen 3.108 N/A HIS 106.A ND1 SER 100.A OG no hydrogen 2.900 N/A LYS 108.A N ASP 105.A O no hydrogen 2.784 N/A TYR 109.A N ASP 105.A O no hydrogen 3.053 N/A TYR 109.A OH GLU 34.A OE1 no hydrogen 3.372 N/A TYR 109.A OH GLU 34.A OE2 no hydrogen 2.686 N/A PHE 110.A N HIS 106.A O no hydrogen 2.830 N/A ARG 111.A N LEU 107.A O no hydrogen 3.152 N/A ARG 111.A NE GLU 234.A OE2 no hydrogen 2.754 N/A ARG 111.A NH2 GLU 234.A OE1 no hydrogen 3.207 N/A ARG 111.A NH2 GLU 234.A OE2 no hydrogen 3.201 N/A PHE 112.A N LYS 108.A O no hydrogen 3.277 N/A ILE 113.A N TYR 109.A O no hydrogen 2.949 N/A GLY 114.A N PHE 110.A O no hydrogen 2.824 N/A ARG 115.A N ARG 111.A O no hydrogen 2.913 N/A ARG 115.A NE GLU 234.A OE2 no hydrogen 3.045 N/A ARG 115.A NH1 ILE 40.A O no hydrogen 3.180 N/A ARG 115.A NH1 PHE 43.A O no hydrogen 3.046 N/A ARG 115.A NH2 GLU 234.A OE2 no hydrogen 3.401 N/A PHE 116.A N PHE 112.A O no hydrogen 2.796 N/A ILE 117.A N ILE 113.A O no hydrogen 3.018 N/A ALA 118.A N GLY 114.A O no hydrogen 3.089 N/A MET 119.A N ARG 115.A O no hydrogen 2.750 N/A ALA 120.A N PHE 116.A O no hydrogen 3.036 N/A LEU 121.A N ILE 117.A O no hydrogen 3.301 N/A PHE 122.A N ALA 118.A O no hydrogen 3.118 N/A HIS 123.A N MET 119.A O no hydrogen 3.015 N/A HIS 123.A NE2 LEU 48.A O no hydrogen 2.755 N/A GLY 124.A N LEU 121.A O no hydrogen 3.379 N/A LYS 125.A N ALA 120.A O no hydrogen 3.038 N/A ILE 127.A N LEU 253.A O no hydrogen 3.150 N/A ASP 128.A N SER 76.A OG no hydrogen 2.945 N/A THR 129.A OG1 SER 76.A O no hydrogen 2.653 N/A THR 129.A OG1 ASP 128.A O no hydrogen 2.687 N/A PHE 131.A N TYR 136.A OH no hydrogen 3.222 N/A TYR 136.A N SER 132.A O no hydrogen 3.140 N/A LYS 137.A N LEU 133.A O no hydrogen 3.233 N/A ARG 138.A N PRO 134.A O no hydrogen 2.996 N/A ILE 139.A N PHE 135.A O no hydrogen 3.144 N/A LEU 140.A N TYR 136.A O no hydrogen 3.005 N/A ASN 141.A N ARG 138.A O no hydrogen 3.076 N/A LYS 142.A N LYS 137.A O no hydrogen 2.836 N/A GLY 145.A N ASP 148.A OD2 no hydrogen 3.374 N/A ASP 148.A N GLY 145.A O no hydrogen 3.232 N/A LEU 149.A N LEU 146.A O no hydrogen 3.126 N/A SER 151.A OG ASP 148.A O no hydrogen 3.005 N/A ASP 153.A N LEU 149.A O no hydrogen 2.739 N/A PHE 156.A N ASP 153.A OD1 no hydrogen 3.209 N/A TYR 157.A N ASP 153.A O no hydrogen 3.263 N/A ASN 158.A N PRO 154.A O no hydrogen 2.810 N/A ASN 158.A ND2 GLU 155.A OE2 no hydrogen 2.864 N/A SER 159.A N GLU 155.A O no hydrogen 3.093 N/A LEU 160.A N PHE 156.A O no hydrogen 2.963 N/A ILE 161.A N TYR 157.A O no hydrogen 2.851 N/A TRP 162.A N ASN 158.A O no hydrogen 3.196 N/A VAL 163.A N SER 159.A O no hydrogen 3.385 N/A LYS 164.A N LEU 160.A O no hydrogen 2.950 N/A GLU 165.A N ILE 161.A O no hydrogen 2.905 N/A ASN 166.A N TRP 162.A O no hydrogen 2.787 N/A ILE 168.A N GLU 202.A OE2 no hydrogen 3.136 N/A CYS 171.A N ASN 167.A O no hydrogen 3.222 N/A LEU 173.A N ILE 168.A O no hydrogen 3.211 N/A PHE 177.A N GLY 195.A O no hydrogen 3.060 N/A PHE 177.A N ILE 198.A O no hydrogen 3.319 N/A SER 178.A N TYR 176.A O no hydrogen 2.792 N/A SER 178.A OG SER 188.A OG no hydrogen 2.668 N/A VAL 179.A N HIS 189.A O no hydrogen 2.886 N/A LYS 181.A N LYS 187.A O no hydrogen 2.736 N/A LYS 187.A N LYS 181.A O no hydrogen 2.751 N/A SER 188.A OG SER 178.A OG no hydrogen 2.668 N/A HIS 189.A N VAL 179.A O no hydrogen 2.691 N/A LEU 191.A N PHE 177.A O no hydrogen 3.008 N/A GLY 195.A N LYS 192.A O no hydrogen 2.876 N/A GLY 196.A N ASP 190.A OD1 no hydrogen 2.881 N/A ASN 197.A N ASN 194.A O no hydrogen 3.371 N/A ASN 197.A ND2 ASN 194.A OD1 no hydrogen 3.617 N/A ILE 198.A N GLY 195.A O no hydrogen 2.917 N/A VAL 200.A N MET 175.A O no hydrogen 2.724 N/A THR 201.A N ASN 204.A OD1 no hydrogen 2.749 N/A THR 201.A OG1 ASN 204.A OD1 no hydrogen 3.112 N/A GLU 202.A N GLU 169.A OE2 no hydrogen 3.079 N/A LYS 205.A NZ VAL 163.A O no hydrogen 2.813 N/A LYS 205.A NZ LYS 164.A O no hydrogen 2.903 N/A LYS 205.A NZ ASN 166.A O no hydrogen 2.767 N/A TYR 208.A N ASN 204.A O no hydrogen 3.005 N/A ILE 209.A N LYS 205.A O no hydrogen 2.931 N/A ARG 210.A N GLU 206.A O no hydrogen 3.059 N/A MET 211.A N GLU 207.A O no hydrogen 2.999 N/A MET 211.A SD GLU 207.A OE2 no hydrogen 3.757 N/A VAL 212.A N TYR 208.A O no hydrogen 2.945 N/A ALA 213.A N ILE 209.A O no hydrogen 3.152 N/A GLU 214.A N ARG 210.A O no hydrogen 2.828 N/A TRP 215.A N MET 211.A O no hydrogen 3.171 N/A ARG 216.A N VAL 212.A O no hydrogen 2.856 N/A ARG 216.A NE ASP 153.A OD2 no hydrogen 2.894 N/A ARG 216.A NH1 ARG 216.A O no hydrogen 2.844 N/A ARG 216.A NH2 ASP 153.A OD2 no hydrogen 2.936 N/A LEU 217.A N ALA 213.A O no hydrogen 3.093 N/A SER 218.A N TRP 215.A O no hydrogen 3.082 N/A SER 218.A OG GLU 214.A O no hydrogen 3.193 N/A GLU 222.A N GLU 222.A OE1 no hydrogen 2.942 N/A GLN 224.A N GLN 224.A OE1 no hydrogen 2.776 N/A GLN 224.A NE2 ASN 97.A O no hydrogen 3.627 N/A GLN 224.A NE2 GLY 220.A O no hydrogen 3.379 N/A THR 225.A N VAL 221.A O no hydrogen 3.040 N/A THR 225.A OG1 VAL 221.A O no hydrogen 2.673 N/A GLN 226.A N GLU 222.A O no hydrogen 2.877 N/A ALA 227.A N GLU 223.A O no hydrogen 2.851 N/A PHE 228.A N GLN 224.A O no hydrogen 2.906 N/A PHE 229.A N THR 225.A O no hydrogen 2.993 N/A GLU 230.A N GLN 226.A O no hydrogen 3.191 N/A GLU 230.A N ALA 227.A O no hydrogen 3.122 N/A GLY 231.A N ALA 227.A O no hydrogen 3.377 N/A PHE 232.A N PHE 228.A O no hydrogen 2.941 N/A ASN 233.A N PHE 229.A O no hydrogen 3.102 N/A ASN 233.A ND2 PHE 229.A O no hydrogen 2.764 N/A ASN 233.A ND2 GLN 238.A OE1 no hydrogen 2.752 N/A ILE 235.A N PHE 232.A O no hydrogen 3.126 N/A LEU 236.A N PHE 232.A O no hydrogen 3.030 N/A GLN 238.A N ASN 233.A OD1 no hydrogen 3.105 N/A GLN 238.A NE2 ILE 139.A O no hydrogen 2.780 N/A TYR 240.A N PRO 237.A O no hydrogen 3.111 N/A LEU 241.A N GLN 238.A O no hydrogen 3.089 N/A GLN 242.A N GLN 239.A O no hydrogen 3.405 N/A GLN 242.A NE2 GLN 239.A O no hydrogen 3.133 N/A PHE 244.A N LEU 241.A O no hydrogen 3.378 N/A ASP 245.A N GLU 248.A OE1 no hydrogen 3.106 N/A GLU 248.A N ASP 245.A OD1 no hydrogen 2.783 N/A LEU 249.A N ASP 245.A O no hydrogen 2.957 N/A LEU 252.A N GLU 248.A O no hydrogen 2.831 N/A LEU 253.A N LEU 249.A O no hydrogen 2.995 N/A CYS 254.A N GLU 250.A O no hydrogen 2.793 N/A CYS 254.A SG THR 129.A O no hydrogen 3.433 N/A CYS 254.A SG GLU 250.A O no hydrogen 3.256 N/A GLY 255.A N VAL 251.A O no hydrogen 2.791 N/A ILE 259.A N ASN 292.A OD1 no hydrogen 3.140 N/A ASN 262.A N ASP 260.A OD1 no hydrogen 3.050 N/A ASP 263.A N ASP 260.A OD1 no hydrogen 3.385 N/A TRP 264.A N ASP 260.A O no hydrogen 3.139 N/A GLN 265.A N LEU 261.A O no hydrogen 3.133 N/A ARG 266.A N ASN 262.A O no hydrogen 3.053 N/A HIS 267.A N ASP 263.A O no hydrogen 3.357 N/A ILE 269.A N PHE 325.A O no hydrogen 2.920 N/A ARG 271.A N ILE 327.A O no hydrogen 3.012 N/A TYR 273.A OH LEU 348.A O no hydrogen 3.163 N/A ALA 274.A N SER 277.A OG no hydrogen 2.852 N/A SER 277.A N ALA 274.A O no hydrogen 3.228 N/A SER 277.A OG ALA 274.A O no hydrogen 3.243 N/A GLN 279.A N GLN 279.A OE1 no hydrogen 2.849 N/A GLN 279.A NE2 TYR 351.A O no hydrogen 2.815 N/A MET 281.A N SER 277.A O no hydrogen 2.944 N/A TRP 282.A N LYS 278.A O no hydrogen 3.095 N/A PHE 283.A N GLN 279.A O no hydrogen 3.047 N/A TRP 284.A N ILE 280.A O no hydrogen 3.319 N/A GLN 285.A N MET 281.A O no hydrogen 3.147 N/A PHE 286.A N TRP 282.A O no hydrogen 2.908 N/A VAL 287.A N PHE 283.A O no hydrogen 2.943 N/A LYS 288.A N TRP 284.A O no hydrogen 3.024 N/A GLU 289.A N GLN 285.A O no hydrogen 3.028 N/A ILE 290.A N PHE 286.A O no hydrogen 2.994 N/A ASN 292.A ND2 GLN 257.A O no hydrogen 2.752 N/A LYS 294.A N ASP 291.A O no hydrogen 2.794 N/A ARG 295.A N ASP 291.A O no hydrogen 3.035 N/A ARG 295.A NE VAL 287.A O no hydrogen 2.781 N/A ARG 295.A NE ILE 290.A O no hydrogen 3.148 N/A ARG 295.A NH1 LYS 288.A O no hydrogen 3.108 N/A ARG 295.A NH1 ILE 290.A O no hydrogen 3.386 N/A MET 296.A N ASN 292.A O no hydrogen 2.987 N/A ARG 297.A NE ILE 365.A O no hydrogen 2.746 N/A ARG 297.A NH1 ASP 245.A OD1 no hydrogen 3.414 N/A ARG 297.A NH2 ASP 245.A OD2 no hydrogen 3.272 N/A LEU 298.A N LYS 294.A O no hydrogen 2.920 N/A LEU 299.A N ARG 295.A O no hydrogen 2.934 N/A GLN 300.A N MET 296.A O no hydrogen 2.801 N/A GLN 300.A NE2 LYS 247.A O no hydrogen 2.956 N/A PHE 301.A N ARG 297.A O no hydrogen 2.894 N/A VAL 302.A N LEU 298.A O no hydrogen 3.225 N/A VAL 302.A N LEU 299.A O no hydrogen 3.279 N/A THR 303.A N LEU 299.A O no hydrogen 2.836 N/A THR 303.A OG1 LEU 299.A O no hydrogen 2.874 N/A GLY 304.A N GLN 300.A O no hydrogen 2.769 N/A THR 305.A N THR 303.A OG1 no hydrogen 3.163 N/A THR 305.A OG1 GLU 250.A OE2 no hydrogen 2.725 N/A CYS 306.A N GLU 250.A OE2 no hydrogen 2.762 N/A CYS 306.A SG GLU 250.A OE2 no hydrogen 3.254 N/A ARG 307.A N THR 305.A OG1 no hydrogen 3.022 N/A PHE 313.A N ASP 263.A OD2 no hydrogen 2.815 N/A GLY 318.A N GLY 321.A O no hydrogen 2.858 N/A SER 319.A N CYS 342.A O no hydrogen 2.745 N/A SER 319.A OG ASN 320.A OD1 no hydrogen 2.964 N/A SER 319.A OG CYS 342.A O no hydrogen 3.479 N/A GLN 323.A N LEU 316.A O no hydrogen 3.272 N/A CYS 326.A N ASN 344.A O no hydrogen 2.974 N/A GLU 328.A N LEU 346.A O no hydrogen 2.716 N/A LYS 329.A N ARG 271.A O no hydrogen 3.137 N/A TRP 335.A N LYS 332.A O no hydrogen 3.089 N/A ARG 338.A N ASP 347.A O no hydrogen 3.317 N/A SER 339.A OG PHE 301.A O no hydrogen 2.849 N/A HIS 340.A N ARG 345.A O no hydrogen 2.856 N/A HIS 340.A ND1 GLU 150.A OE2 no hydrogen 2.718 N/A HIS 340.A NE2 ASP 347.A OD2 no hydrogen 2.743 N/A PHE 343.A N HIS 340.A O no hydrogen 3.069 N/A ASN 344.A ND2 MET 317.A O no hydrogen 3.340 N/A ASN 344.A ND2 GLN 323.A O no hydrogen 3.047 N/A ARG 345.A N HIS 340.A O no hydrogen 3.180 N/A LEU 346.A N CYS 326.A O no hydrogen 2.732 N/A ASP 347.A N ARG 338.A O no hydrogen 2.970 N/A LEU 348.A N GLU 328.A O no hydrogen 2.771 N/A TYR 351.A OH TRP 335.A O no hydrogen 3.285 N/A LYS 352.A N GLN 356.A OE1 no hydrogen 3.405 N/A TYR 354.A OH GLU 289.A OE1 no hydrogen 2.884 N/A LEU 357.A N SER 353.A O no hydrogen 3.371 N/A LYS 358.A N TYR 354.A O no hydrogen 2.757 N/A GLU 359.A N GLU 355.A O no hydrogen 2.882 N/A LYS 360.A N GLN 356.A O no hydrogen 2.834 N/A LEU 361.A N LEU 357.A O no hydrogen 2.796 N/A LEU 362.A N LYS 358.A O no hydrogen 3.176 N/A PHE 363.A N GLU 359.A O no hydrogen 3.289 N/A ALA 364.A N LYS 360.A O no hydrogen 2.987 N/A ILE 365.A N LEU 361.A O no hydrogen 2.911 N/A GLU 366.A N LEU 362.A O no hydrogen 3.326 N/A GLU 367.A N PHE 363.A O no hydrogen 2.754 N/A GLU 369.A N.B GLU 369.A OE1.B no hydrogen 2.728 N/A GLY 370.A N GLU 369.A OE1.A no hydrogen 3.275 N/A