Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5cd5_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): TRP 2.A NE1 GLU 48.A OE2 no hydrogen 2.705 N/A LYS 3.A N GLN 341.A O no hydrogen 2.715 N/A ALA 5.A N VAL 339.A O no hydrogen 3.486 N/A LEU 9.A N GLN 60.A OE1 no hydrogen 2.824 N/A PHE 10.A N CYS 102.A O no hydrogen 3.171 N/A CYS 11.A SG ALA 30.A O no hydrogen 3.178 N/A ALA 12.A N HIS 100.A O no hydrogen 2.822 N/A SER 13.A N VAL 32.A O no hydrogen 2.890 N/A ALA 15.A N SER 13.A OG no hydrogen 3.192 N/A LYS 16.A N ASN 24.A OD1 no hydrogen 2.956 N/A LYS 16.A NZ ASP 14.A O no hydrogen 3.540 N/A LYS 16.A NZ ASN 24.A OD1 no hydrogen 3.359 N/A GLU 19.A N LYS 16.A O no hydrogen 3.101 N/A THR 20.A N GLU 19.A OE2 no hydrogen 2.779 N/A THR 20.A OG1 GLU 19.A OE2 no hydrogen 3.536 N/A GLU 21.A N GLU 19.A OE2 no hydrogen 3.104 N/A VAL 22.A N SER 93.A O no hydrogen 3.124 N/A HIS 23.A N GLU 21.A OE2 no hydrogen 3.063 N/A HIS 23.A ND1 GLU 21.A OE2 no hydrogen 2.554 N/A ASN 24.A N GLU 21.A OE1 no hydrogen 2.858 N/A ASN 24.A ND2 GLU 21.A OE1 no hydrogen 2.714 N/A VAL 25.A N GLU 21.A O no hydrogen 2.989 N/A TRP 26.A N VAL 22.A O no hydrogen 3.065 N/A ALA 27.A N HIS 23.A O no hydrogen 3.018 N/A THR 28.A N ASN 24.A O no hydrogen 2.883 N/A THR 28.A OG1 ASN 24.A O no hydrogen 2.790 N/A HIS 29.A N TRP 26.A O no hydrogen 3.113 N/A ALA 30.A N TRP 26.A O no hydrogen 2.715 N/A CYS 31.A N ALA 27.A O no hydrogen 2.793 N/A VAL 32.A N CYS 11.A O no hydrogen 3.225 N/A THR 34.A OG1 ASP 14.A OD1 no hydrogen 2.367 N/A ASN 37.A N ASP 35.A OD1 no hydrogen 2.934 N/A GLN 39.A NE2 ASN 37.A O no hydrogen 3.460 N/A ILE 41.A N SER 128.A O no hydrogen 3.155 N/A LEU 43.A N VAL 126.A O no hydrogen 2.881 N/A GLU 48.A N CYS 123.A O no hydrogen 2.747 N/A PHE 50.A N GLY 121.A O no hydrogen 3.031 N/A MET 52.A N GLY 119.A O no hydrogen 2.805 N/A TRP 53.A N ASN 51.A OD1 no hydrogen 3.161 N/A LYS 54.A N ASN 51.A O no hydrogen 3.029 N/A ASN 55.A ND2 TYR 337.A O no hydrogen 2.908 N/A MET 57.A N ASN 55.A OD1 no hydrogen 3.202 N/A VAL 58.A N ASN 55.A O no hydrogen 2.889 N/A GLU 59.A N GLU 59.A OE2 no hydrogen 2.909 N/A GLN 60.A N ASN 56.A O no hydrogen 3.173 N/A GLN 60.A NE2 THR 7.A O no hydrogen 2.733 N/A GLN 60.A NE2 ASN 56.A OD1 no hydrogen 2.768 N/A MET 61.A N MET 57.A O no hydrogen 3.228 N/A GLN 62.A N VAL 58.A O no hydrogen 3.222 N/A GLU 63.A N GLU 59.A O no hydrogen 3.352 N/A ASP 64.A N GLN 60.A O no hydrogen 3.309 N/A VAL 65.A N MET 61.A O no hydrogen 3.038 N/A ILE 66.A N GLN 62.A O no hydrogen 2.880 N/A SER 67.A N GLU 63.A O no hydrogen 2.892 N/A SER 67.A OG GLN 71.A OE1 no hydrogen 3.351 N/A LEU 68.A N ASP 64.A O no hydrogen 2.717 N/A TRP 69.A N VAL 65.A O no hydrogen 2.974 N/A ASP 70.A N ILE 66.A O no hydrogen 3.020 N/A GLN 71.A N SER 67.A O no hydrogen 3.358 N/A SER 72.A N TRP 69.A O no hydrogen 3.323 N/A SER 72.A OG LEU 68.A O no hydrogen 2.595 N/A LEU 73.A N TRP 69.A O no hydrogen 2.835 N/A CYS 76.A N MET 285.A O no hydrogen 2.908 N/A VAL 77.A N MET 285.A O no hydrogen 3.154 N/A LYS 78.A N ILE 85.A O no hydrogen 3.211 N/A LEU 79.A N GLN 283.A O no hydrogen 2.401 N/A THR 80.A N SER 83.A O no hydrogen 2.840 N/A THR 80.A OG1 THR 281.A O no hydrogen 2.968 N/A SER 83.A N THR 80.A O no hydrogen 2.689 N/A SER 83.A OG THR 80.A O no hydrogen 2.526 N/A ILE 85.A N LYS 78.A O no hydrogen 3.115 N/A LYS 91.A NZ GLU 242.A OE1 no hydrogen 3.326 N/A LYS 91.A NZ GLU 242.A OE2 no hydrogen 2.928 N/A LYS 91.A NZ ALA 287.A O no hydrogen 3.203 N/A LYS 91.A NZ PRO 288.A O no hydrogen 3.194 N/A ASP 95.A N GLU 21.A OE2 no hydrogen 2.956 N/A ILE 99.A N ILE 135.A O no hydrogen 2.815 N/A HIS 100.A N ALA 12.A O no hydrogen 2.917 N/A HIS 100.A ND1 THR 132.A O no hydrogen 2.789 N/A TYR 101.A N THR 132.A OG1 no hydrogen 2.885 N/A TYR 101.A OH ASP 64.A OD2 no hydrogen 3.025 N/A CYS 102.A N PHE 10.A O no hydrogen 2.919 N/A THR 103.A N GLN 130.A O no hydrogen 3.295 N/A THR 103.A OG1 TYR 107.A O no hydrogen 3.500 N/A TYR 107.A N PRO 104.A O no hydrogen 3.188 N/A VAL 108.A N VAL 340.A O no hydrogen 3.044 N/A ILE 109.A N VAL 129.A O no hydrogen 3.226 N/A LEU 110.A N LYS 338.A O no hydrogen 2.949 N/A LYS 111.A N SER 127.A O no hydrogen 2.826 N/A CYS 112.A N LYS 336.A O no hydrogen 3.014 N/A ASN 113.A N ASN 125.A O no hydrogen 2.682 N/A ASN 113.A ND2 ASN 125.A O no hydrogen 3.533 N/A ASN 113.A ND2 SER 127.A OG no hydrogen 3.108 N/A PHE 117.A N ASP 114.A O no hydrogen 3.212 N/A THR 120.A N ASN 118.A OD1 no hydrogen 2.834 N/A THR 120.A OG1 ASN 118.A OD1 no hydrogen 3.320 N/A GLY 121.A N PHE 50.A O no hydrogen 3.186 N/A CYS 123.A N GLU 48.A O no hydrogen 2.688 N/A CYS 123.A SG ASN 125.A O no hydrogen 3.032 N/A ASN 125.A N ASP 114.A OD1 no hydrogen 3.162 N/A ASN 125.A ND2 ASN 113.A O no hydrogen 3.560 N/A SER 127.A N LYS 111.A O no hydrogen 2.896 N/A SER 127.A OG GLU 40.A OE2 no hydrogen 2.724 N/A SER 127.A OG ASN 113.A OD1 no hydrogen 3.431 N/A SER 128.A N ILE 41.A O no hydrogen 2.915 N/A SER 128.A OG ILE 41.A O no hydrogen 3.459 N/A VAL 129.A N ILE 109.A O no hydrogen 2.946 N/A THR 132.A N TYR 101.A O no hydrogen 2.986 N/A THR 132.A OG1 TYR 101.A O no hydrogen 3.380 N/A THR 132.A OG1 HIS 133.A O no hydrogen 3.285 N/A HIS 133.A N TYR 337.A OH no hydrogen 3.363 N/A HIS 133.A ND1 TYR 337.A OH no hydrogen 2.579 N/A HIS 133.A NE2 GLU 333.A OE1 no hydrogen 3.295 N/A ILE 135.A N ILE 99.A O no hydrogen 2.947 N/A VAL 138.A N LYS 136.A O no hydrogen 2.877 N/A SER 140.A OG LEU 143.A O no hydrogen 2.743 N/A THR 141.A N HIS 236.A O no hydrogen 3.116 N/A THR 141.A OG1 GLU 231.A O no hydrogen 2.587 N/A THR 141.A OG1 MET 234.A O no hydrogen 3.262 N/A GLN 142.A NE2 ILE 232.A O no hydrogen 2.496 N/A LEU 143.A N THR 141.A O no hydrogen 2.566 N/A LEU 144.A N GLY 302.A O no hydrogen 2.899 N/A ASN 146.A N ASN 299.A O no hydrogen 3.311 N/A GLY 147.A N THR 301.A OG1 no hydrogen 3.306 N/A SER 148.A N GLU 333.A OE1 no hydrogen 3.287 N/A SER 148.A N GLU 333.A OE2 no hydrogen 2.831 N/A SER 148.A OG HIS 133.A NE2 no hydrogen 3.158 N/A SER 148.A OG GLU 333.A OE1 no hydrogen 2.841 N/A ALA 150.A N LEU 172.A O no hydrogen 2.884 N/A GLU 153.A N ASN 116.A OD1 no hydrogen 3.030 N/A ILE 155.A N HIS 171.A O no hydrogen 3.289 N/A ARG 157.A N ILE 169.A O no hydrogen 2.717 N/A ARG 157.A NH1 PHE 117.A O no hydrogen 2.873 N/A ARG 157.A NH2 PHE 117.A O no hydrogen 3.377 N/A ARG 157.A NH2 HIS 171.A ND1 no hydrogen 3.148 N/A SER 158.A OG ASN 160.A O no hydrogen 2.813 N/A ASN 163.A N ASN 160.A OD1 no hydrogen 3.007 N/A LYS 166.A N ASN 163.A OD1 no hydrogen 2.620 N/A LYS 166.A NZ GLU 159.A OE1 no hydrogen 3.086 N/A ILE 168.A N LEU 305.A O no hydrogen 2.761 N/A ILE 169.A N ARG 157.A O no hydrogen 2.601 N/A VAL 170.A N ILE 303.A O no hydrogen 2.702 N/A HIS 171.A N ILE 155.A O no hydrogen 2.841 N/A HIS 171.A NE2 SER 148.A O no hydrogen 2.609 N/A LEU 172.A N THR 301.A O no hydrogen 3.001 N/A ASN 173.A ND2 GLU 152.A O no hydrogen 3.001 N/A VAL 176.A N ILE 300.A O no hydrogen 3.297 N/A ILE 178.A N SER 298.A O no hydrogen 2.305 N/A ASN 179.A N GLU 194.A O no hydrogen 3.397 N/A CYS 180.A N CYS 296.A O no hydrogen 3.201 N/A THR 181.A N TYR 192.A O no hydrogen 2.973 N/A THR 181.A OG1 ASN 179.A OD1 no hydrogen 3.169 N/A ARG 182.A N ILE 294.A O no hydrogen 2.738 N/A ARG 182.A NE PRO 183.A O no hydrogen 3.179 N/A ARG 182.A NE GLY 292.A O no hydrogen 3.459 N/A ARG 182.A NH1 ILE 188.A O no hydrogen 2.378 N/A ARG 182.A NH2 ILE 290.A O no hydrogen 2.357 N/A ARG 182.A NH2 GLY 292.A O no hydrogen 3.014 N/A ARG 189.A N ASP 187.A OD1 no hydrogen 2.959 N/A ARG 189.A NE GLN 273.A OE1 no hydrogen 2.936 N/A ARG 189.A NH2 GLN 273.A OE1 no hydrogen 2.852 N/A LYS 190.A N ASP 187.A O no hydrogen 3.093 N/A ALA 191.A N CYS 269.A O no hydrogen 3.363 N/A TYR 192.A N THR 181.A O no hydrogen 3.295 N/A CYS 193.A N LEU 267.A O no hydrogen 3.045 N/A GLU 194.A N ASN 179.A O no hydrogen 2.799 N/A ILE 195.A N ILE 265.A O no hydrogen 2.708 N/A GLY 197.A N GLY 263.A O no hydrogen 2.889 N/A THR 198.A OG1 ASN 262.A O no hydrogen 2.372 N/A LYS 199.A N ASN 196.A OD1 no hydrogen 2.759 N/A TRP 200.A N ASN 196.A O no hydrogen 2.968 N/A TRP 200.A NE1 LEU 251.A O no hydrogen 2.691 N/A ASN 201.A N GLY 197.A O no hydrogen 2.920 N/A LYS 202.A N THR 198.A O no hydrogen 3.312 N/A VAL 203.A N LYS 199.A O no hydrogen 3.210 N/A LEU 204.A N TRP 200.A O no hydrogen 2.756 N/A LYS 205.A N ASN 201.A O no hydrogen 2.986 N/A LYS 205.A NZ GLU 209.A OE2 no hydrogen 3.289 N/A GLN 206.A N LYS 202.A O no hydrogen 3.337 N/A VAL 207.A N VAL 203.A O no hydrogen 2.972 N/A THR 208.A N LEU 204.A O no hydrogen 3.003 N/A THR 208.A OG1 LEU 204.A O no hydrogen 3.079 N/A GLU 209.A N LYS 205.A O no hydrogen 3.090 N/A LYS 210.A N GLN 206.A O no hydrogen 2.873 N/A LYS 210.A NZ GLU 213.A OE1 no hydrogen 2.762 N/A LEU 211.A N VAL 207.A O no hydrogen 2.921 N/A LYS 212.A N THR 208.A O no hydrogen 3.039 N/A LYS 212.A NZ LYS 218.A O no hydrogen 3.308 N/A GLU 213.A N GLU 209.A O no hydrogen 3.220 N/A GLU 213.A N LYS 210.A O no hydrogen 3.114 N/A HIS 214.A N LEU 211.A O no hydrogen 3.101 N/A PHE 215.A N LEU 211.A O no hydrogen 3.237 N/A PHE 215.A N LYS 212.A O no hydrogen 3.318 N/A ASN 217.A N LYS 212.A O no hydrogen 2.949 N/A LYS 218.A N PHE 215.A O no hydrogen 2.976 N/A LYS 218.A NZ THR 314.A O no hydrogen 3.554 N/A LYS 218.A NZ ASN 316.A O no hydrogen 3.162 N/A LYS 218.A NZ GLU 317.A OE2 no hydrogen 2.925 N/A ILE 221.A N GLU 317.A O no hydrogen 2.927 N/A PHE 222.A N ASN 254.A OD1 no hydrogen 2.763 N/A GLN 223.A N PHE 319.A O no hydrogen 3.053 N/A GLU 231.A N GLU 231.A OE1 no hydrogen 2.785 N/A ILE 232.A N ASP 229.A O no hydrogen 3.077 N/A THR 233.A N ASP 229.A O no hydrogen 3.080 N/A THR 233.A OG1 ASP 229.A O no hydrogen 3.239 N/A MET 234.A N LEU 230.A O no hydrogen 3.102 N/A HIS 235.A N CYS 246.A O no hydrogen 2.460 N/A HIS 235.A ND1 THR 141.A O no hydrogen 3.130 N/A HIS 236.A N THR 141.A OG1 no hydrogen 3.238 N/A PHE 237.A N PHE 244.A O no hydrogen 3.357 N/A CYS 239.A N GLU 242.A O no hydrogen 2.891 N/A ARG 240.A NE ASN 295.A O no hydrogen 3.386 N/A GLY 241.A N ASN 238.A OD1 no hydrogen 3.008 N/A GLU 242.A N CYS 239.A O no hydrogen 2.896 N/A PHE 244.A N PHE 237.A O no hydrogen 2.970 N/A TYR 245.A N LYS 270.A O no hydrogen 2.937 N/A TYR 245.A OH GLU 231.A OE2 no hydrogen 2.450 N/A CYS 246.A N HIS 235.A O no hydrogen 2.698 N/A ASN 247.A N PRO 268.A O no hydrogen 3.059 N/A THR 248.A OG1 GLN 142.A OE1 no hydrogen 3.094 N/A THR 249.A N ASN 247.A OD1 no hydrogen 2.811 N/A THR 249.A OG1 ASN 247.A OD1 no hydrogen 3.051 N/A GLN 250.A NE2 THR 266.A O no hydrogen 2.414 N/A LEU 251.A N THR 248.A O no hydrogen 2.862 N/A PHE 252.A N THR 248.A O no hydrogen 3.489 N/A ASN 254.A ND2 PHE 222.A O no hydrogen 2.597 N/A THR 255.A N ASN 253.A OD1 no hydrogen 3.153 N/A THR 255.A OG1 ASN 253.A OD1 no hydrogen 2.602 N/A CYS 256.A SG CYS 261.A O no hydrogen 3.983 N/A ILE 257.A N ASN 254.A O no hydrogen 3.022 N/A CYS 261.A SG LYS 259.A O no hydrogen 3.842 N/A ILE 265.A N ILE 195.A O no hydrogen 2.601 N/A LEU 267.A N CYS 193.A O no hydrogen 2.754 N/A CYS 269.A N ALA 191.A O no hydrogen 3.114 N/A CYS 269.A SG LEU 267.A O no hydrogen 3.621 N/A LYS 270.A N TYR 245.A O no hydrogen 3.012 N/A ILE 271.A N ARG 189.A O no hydrogen 2.871 N/A LYS 272.A N PHE 243.A O no hydrogen 3.250 N/A LYS 272.A NZ ILE 274.A O no hydrogen 3.145 N/A GLN 273.A NE2 TYR 286.A O no hydrogen 2.960 N/A ILE 275.A N ALA 284.A O no hydrogen 2.934 N/A ASN 276.A N GLU 231.A OE2 no hydrogen 2.803 N/A ASN 276.A ND2 GLU 231.A OE1 no hydrogen 3.013 N/A ASN 276.A ND2 GLU 231.A OE2 no hydrogen 3.514 N/A MET 277.A N GLY 282.A O no hydrogen 2.678 N/A GLN 279.A N GLN 279.A OE1 no hydrogen 2.679 N/A GLN 279.A NE2 ASP 70.A OD1 no hydrogen 3.453 N/A GLY 280.A N MET 277.A O no hydrogen 2.870 N/A GLN 283.A N LEU 79.A O no hydrogen 2.786 N/A GLN 283.A NE2 ASN 276.A OD1 no hydrogen 2.635 N/A ALA 284.A N ILE 275.A O no hydrogen 3.009 N/A MET 285.A N VAL 77.A O no hydrogen 2.625 N/A TYR 286.A N GLN 273.A O no hydrogen 2.750 N/A TYR 286.A OH LEU 73.A O no hydrogen 3.060 N/A ILE 290.A N GLU 242.A OE2 no hydrogen 3.448 N/A ILE 294.A N ARG 182.A O no hydrogen 3.056 N/A ASN 295.A ND2 ASN 179.A OD1 no hydrogen 2.473 N/A ASN 295.A ND2 THR 181.A OG1 no hydrogen 2.583 N/A CYS 296.A N CYS 180.A O no hydrogen 3.156 N/A SER 298.A N ILE 178.A O no hydrogen 2.709 N/A ILE 300.A N VAL 176.A O no hydrogen 2.464 N/A THR 301.A N LEU 144.A O no hydrogen 2.979 N/A THR 301.A OG1 LEU 144.A O no hydrogen 3.206 N/A THR 301.A OG1 GLY 147.A O no hydrogen 3.289 N/A ILE 303.A N VAL 170.A O no hydrogen 2.903 N/A LEU 304.A N GLN 142.A O no hydrogen 2.597 N/A LEU 305.A N ILE 168.A O no hydrogen 2.719 N/A THR 306.A N ARG 320.A O no hydrogen 2.798 N/A THR 306.A OG1 GLY 322.A O no hydrogen 3.354 N/A ARG 307.A NH1 GLU 317.A OE1 no hydrogen 3.201 N/A ARG 307.A NH2 LEU 161.A O no hydrogen 3.398 N/A ASP 308.A N THR 318.A O no hydrogen 2.848 N/A GLU 317.A N THR 219.A O no hydrogen 2.842 N/A PHE 319.A N ILE 221.A O no hydrogen 2.765 N/A ARG 320.A N THR 306.A O no hydrogen 2.939 N/A ARG 320.A NE ASP 308.A OD1 no hydrogen 3.125 N/A ARG 320.A NE ASP 308.A OD2 no hydrogen 3.426 N/A ARG 320.A NH1 PRO 224.A O no hydrogen 2.591 N/A ARG 320.A NH2 ASP 308.A OD2 no hydrogen 3.264 N/A GLY 322.A N LEU 304.A O no hydrogen 2.856 N/A GLY 324.A N THR 167.A OG1 no hydrogen 3.409 N/A LYS 327.A N ASN 325.A OD1 no hydrogen 2.875 N/A LYS 327.A NZ GLU 59.A OE1 no hydrogen 3.289 N/A ASN 329.A N ILE 326.A O no hydrogen 3.023 N/A ASN 329.A ND2 VAL 138.A O no hydrogen 3.532 N/A ASN 329.A ND2 SER 140.A O no hydrogen 2.932 N/A TRP 330.A NE1 GLN 62.A OE1 no hydrogen 2.658 N/A ARG 331.A N LYS 327.A O no hydrogen 2.850 N/A ARG 331.A NH1 ASP 328.A OD1 no hydrogen 2.653 N/A SER 332.A N ASP 328.A O no hydrogen 2.991 N/A SER 332.A OG ASN 329.A O no hydrogen 2.706 N/A GLU 333.A N TRP 330.A O no hydrogen 2.975 N/A LEU 334.A N TRP 330.A O no hydrogen 2.880 N/A LEU 334.A N ARG 331.A O no hydrogen 3.260 N/A TYR 337.A N LEU 334.A O no hydrogen 2.961 N/A TYR 337.A OH HIS 133.A ND1 no hydrogen 2.579 N/A LYS 338.A N LEU 110.A O no hydrogen 3.238 N/A LYS 338.A NZ ASP 4.A OD1 no hydrogen 3.210 N/A LYS 338.A NZ ASP 4.A OD2 no hydrogen 3.415 N/A LYS 338.A NZ GLU 48.A OE1 no hydrogen 3.190 N/A LYS 338.A NZ ASN 49.A O no hydrogen 2.716 N/A VAL 340.A N VAL 108.A O no hydrogen 3.003 N/A GLN 341.A N LYS 3.A O no hydrogen 2.332 N/A ILE 342.A N GLY 106.A O no hydrogen 2.826 N/A