Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5cdh_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 2.A N LEU 285.A O no hydrogen 2.771 N/A ALA 4.A N LYS 249.A O no hydrogen 3.059 N/A VAL 5.A N PHE 283.A O no hydrogen 2.853 N/A ASP 6.A N VAL 251.A O no hydrogen 3.006 N/A ILE 7.A N VAL 281.A O no hydrogen 2.870 N/A ILE 8.A N LEU 253.A O no hydrogen 2.879 N/A ARG 9.A N SER 279.A O no hydrogen 2.907 N/A HIS 10.A N ALA 255.A O no hydrogen 3.180 N/A HIS 10.A ND1 GLY 11.A O no hydrogen 2.830 N/A GLY 11.A N SER 81.A OG no hydrogen 3.146 N/A ASP 12.A N GLN 40.A OE1 no hydrogen 2.869 N/A ARG 13.A NH1 THR 14.A O no hydrogen 2.975 N/A THR 14.A N GLN 32.A O no hydrogen 2.902 N/A THR 14.A OG1 GLY 29.A O no hydrogen 2.563 N/A THR 21.A OG1 LEU 165.A O no hydrogen 2.631 N/A VAL 22.A N LEU 19.A O no hydrogen 3.061 N/A GLN 25.A NE2 TRP 26.A O no hydrogen 3.588 N/A GLU 28.A N GLU 28.A OE1 no hydrogen 2.610 N/A GLY 29.A N TRP 26.A O no hydrogen 2.860 N/A GLY 31.A N PRO 15.A O no hydrogen 2.824 N/A GLN 32.A N THR 14.A OG1 no hydrogen 3.057 N/A GLN 32.A NE2 LEU 30.A O no hydrogen 3.015 N/A THR 34.A N ASP 12.A O no hydrogen 2.943 N/A THR 34.A OG1 ASP 12.A O no hydrogen 3.111 N/A THR 34.A OG1 ASP 12.A OD2 no hydrogen 2.523 N/A THR 34.A OG1 GLU 36.A OE1 no hydrogen 3.294 N/A GLU 36.A N GLU 36.A OE1 no hydrogen 2.877 N/A GLY 37.A N THR 34.A OG1 no hydrogen 3.066 N/A MET 38.A N THR 34.A O no hydrogen 2.906 N/A GLN 39.A N ALA 35.A O no hydrogen 3.175 N/A GLN 40.A N GLU 36.A O no hydrogen 2.979 N/A GLU 41.A N GLY 37.A O no hydrogen 3.078 N/A TYR 42.A N MET 38.A O no hydrogen 2.930 N/A LYS 43.A N GLN 39.A O no hydrogen 2.913 N/A LYS 43.A NZ GLN 39.A OE1 no hydrogen 3.181 N/A MET 44.A N GLN 40.A O no hydrogen 3.070 N/A GLY 45.A N GLU 41.A O no hydrogen 2.912 N/A VAL 46.A N TYR 42.A O no hydrogen 2.831 N/A ALA 47.A N LYS 43.A O no hydrogen 2.950 N/A PHE 48.A N MET 44.A O no hydrogen 2.790 N/A ARG 49.A N GLY 45.A O no hydrogen 2.906 N/A ARG 49.A NH1 GLU 61.A O no hydrogen 3.093 N/A ARG 49.A NH1 LEU 89.A O no hydrogen 2.945 N/A ARG 49.A NH2 GLU 61.A O no hydrogen 3.012 N/A LYS 50.A N VAL 46.A O no hydrogen 3.070 N/A LYS 50.A NZ GLU 55.A OE2 no hydrogen 2.512 N/A LYS 51.A N ALA 47.A O no hydrogen 3.058 N/A TYR 52.A N PHE 48.A O no hydrogen 2.775 N/A TYR 52.A OH ASP 6.A OD1 no hydrogen 3.381 N/A TYR 52.A OH ASP 6.A OD2 no hydrogen 2.586 N/A ILE 53.A N ARG 49.A O no hydrogen 3.072 N/A GLU 54.A N ARG 49.A O no hydrogen 2.947 N/A GLU 55.A N LYS 50.A O no hydrogen 2.936 N/A LEU 56.A N LYS 51.A O no hydrogen 2.901 N/A LEU 59.A N TYR 52.A O no hydrogen 3.100 N/A HIS 62.A ND1 THR 94.A O no hydrogen 2.832 N/A THR 67.A N GLU 64.A O no hydrogen 3.290 N/A THR 67.A OG1 GLU 64.A O no hydrogen 2.781 N/A TYR 69.A N TYR 250.A O no hydrogen 2.875 N/A ARG 71.A N LEU 252.A O no hydrogen 2.896 N/A ARG 71.A NH1 TYR 69.A OH no hydrogen 3.263 N/A ARG 71.A NH2 ASP 122.A OD1 no hydrogen 2.946 N/A SER 72.A N PHE 115.A O no hydrogen 2.798 N/A SER 72.A OG THR 73.A O no hydrogen 3.047 N/A THR 73.A N SER 254.A O no hydrogen 3.190 N/A THR 73.A OG1 THR 78.A OG1 no hydrogen 2.797 N/A THR 73.A OG1 HIS 256.A NE2 no hydrogen 2.822 N/A TYR 75.A N THR 73.A O no hydrogen 2.975 N/A ARG 77.A NH1 GLY 31.A O no hydrogen 3.106 N/A THR 78.A N TYR 75.A O no hydrogen 3.240 N/A THR 78.A OG1 SER 72.A OG no hydrogen 2.980 N/A THR 78.A OG1 THR 73.A O no hydrogen 3.148 N/A THR 78.A OG1 THR 73.A OG1 no hydrogen 2.797 N/A THR 78.A OG1 TYR 75.A O no hydrogen 3.147 N/A LEU 79.A N TYR 75.A O no hydrogen 3.019 N/A MET 80.A N ALA 76.A O no hydrogen 2.794 N/A SER 81.A N ARG 77.A O no hydrogen 3.080 N/A SER 81.A OG ARG 77.A O no hydrogen 2.673 N/A ALA 82.A N THR 78.A O no hydrogen 2.960 N/A GLN 83.A N LEU 79.A O no hydrogen 2.989 N/A SER 84.A N MET 80.A O no hydrogen 2.861 N/A SER 84.A OG MET 80.A O no hydrogen 2.855 N/A LEU 85.A N SER 81.A O no hydrogen 2.918 N/A LEU 86.A N ALA 82.A O no hydrogen 2.970 N/A MET 87.A N GLN 83.A O no hydrogen 3.178 N/A GLY 88.A N LEU 85.A O no hydrogen 2.775 N/A LEU 89.A N LEU 85.A O no hydrogen 2.866 N/A TYR 90.A N LEU 86.A O no hydrogen 2.887 N/A TYR 90.A OH PRO 60.A O no hydrogen 2.706 N/A GLY 93.A N ALA 108.A O no hydrogen 2.938 N/A THR 94.A N PRO 91.A O no hydrogen 2.970 N/A THR 94.A OG1 PRO 91.A O no hydrogen 2.736 N/A GLY 95.A N ALA 108.A O no hydrogen 2.850 N/A SER 97.A OG GLY 101.A O no hydrogen 3.180 N/A ILE 98.A N THR 102.A O no hydrogen 2.843 N/A GLY 101.A N ILE 98.A O no hydrogen 2.795 N/A ALA 104.A N PRO 96.A O no hydrogen 2.930 N/A ALA 108.A N LEU 105.A O no hydrogen 3.045 N/A PHE 109.A N PRO 106.A O no hydrogen 3.238 N/A GLN 110.A NE2 PRO 111.A O no hydrogen 2.804 N/A PHE 115.A N VAL 70.A O no hydrogen 2.897 N/A TYR 121.A N PRO 118.A O no hydrogen 2.898 N/A VAL 124.A N ASP 122.A OD1 no hydrogen 2.904 N/A ILE 125.A N ASP 122.A OD1 no hydrogen 3.189 N/A ILE 125.A N ASP 122.A OD2 no hydrogen 3.318 N/A ILE 126.A N ASP 122.A OD2 no hydrogen 2.877 N/A GLN 127.A NE2 GLN 128.A O no hydrogen 3.219 N/A ARG 134.A N ASP 130.A O no hydrogen 2.842 N/A ARG 134.A NH1 TYR 226.A OH no hydrogen 3.060 N/A LYS 135.A N ARG 131.A O no hydrogen 3.064 N/A LYS 136.A N LYS 132.A O no hydrogen 3.045 N/A LEU 137.A N GLU 133.A O no hydrogen 2.932 N/A MET 138.A N ARG 134.A O no hydrogen 2.844 N/A GLU 139.A N LYS 135.A O no hydrogen 2.836 N/A GLN 140.A N LYS 136.A O no hydrogen 3.069 N/A TYR 141.A N LEU 137.A O no hydrogen 2.974 N/A VAL 142.A N MET 138.A O no hydrogen 2.891 N/A PHE 143.A N MET 138.A O no hydrogen 2.831 N/A SER 144.A OG GLU 139.A O no hydrogen 2.887 N/A SER 144.A OG GLN 140.A O no hydrogen 2.917 N/A THR 145.A N VAL 142.A O no hydrogen 3.225 N/A THR 145.A OG1 VAL 142.A O no hydrogen 3.030 N/A GLU 147.A N GLU 147.A OE1 no hydrogen 2.665 N/A TRP 148.A N THR 145.A OG1 no hydrogen 3.193 N/A GLN 149.A N THR 145.A O no hydrogen 3.285 N/A GLN 149.A NE2 PHE 143.A O no hydrogen 2.357 N/A GLN 150.A N ARG 146.A O no hydrogen 2.934 N/A GLN 150.A NE2 GLU 154.A OE2 no hydrogen 3.135 N/A LYS 151.A N GLU 147.A O no hydrogen 2.977 N/A ASN 152.A N TRP 148.A O no hydrogen 3.021 N/A ASN 153.A N GLN 149.A O no hydrogen 2.885 N/A GLU 154.A N GLN 150.A O no hydrogen 3.023 N/A LEU 155.A N LYS 151.A O no hydrogen 3.204 N/A LEU 155.A N ASN 152.A O no hydrogen 3.214 N/A LYS 156.A N ASN 152.A O no hydrogen 2.983 N/A LYS 158.A N LEU 155.A O no hydrogen 2.864 N/A LYS 158.A NZ ASP 201.A OD1 no hydrogen 2.937 N/A TYR 159.A N LYS 156.A O no hydrogen 3.006 N/A TYR 159.A OH ASN 152.A OD1 no hydrogen 2.788 N/A TRP 162.A N LYS 158.A O no hydrogen 2.966 N/A TRP 162.A NE1 ASP 201.A OD2 no hydrogen 2.848 N/A SER 163.A N TYR 159.A O no hydrogen 2.913 N/A SER 163.A OG TYR 159.A O no hydrogen 2.643 N/A ARG 164.A N PRO 160.A O no hydrogen 3.075 N/A LEU 165.A N LEU 161.A O no hydrogen 2.858 N/A THR 166.A N TRP 162.A O no hydrogen 2.996 N/A THR 166.A OG1 TRP 162.A O no hydrogen 2.723 N/A GLY 167.A N SER 163.A O no hydrogen 2.877 N/A ILE 168.A N THR 166.A OG1 no hydrogen 3.216 N/A ASN 169.A ND2 ASP 171.A OD2 no hydrogen 2.877 N/A ILE 170.A N SER 163.A OG no hydrogen 2.931 N/A ASP 171.A N ASP 175.A OD2 no hydrogen 2.798 N/A THR 172.A N ASP 175.A OD2 no hydrogen 3.108 N/A ASP 175.A N THR 172.A O no hydrogen 3.036 N/A LEU 176.A N LEU 173.A O no hydrogen 3.053 N/A GLU 177.A N GLU 174.A O no hydrogen 3.101 N/A GLY 180.A N LEU 176.A O no hydrogen 2.787 N/A HIS 181.A N GLU 177.A O no hydrogen 2.919 N/A THR 182.A N THR 178.A O no hydrogen 2.999 N/A THR 182.A OG1 VAL 17.A O no hydrogen 3.096 N/A THR 182.A OG1 THR 178.A O no hydrogen 3.189 N/A LEU 183.A N VAL 179.A O no hydrogen 2.866 N/A TYR 184.A N GLY 180.A O no hydrogen 2.937 N/A VAL 185.A N HIS 181.A O no hydrogen 3.116 N/A HIS 186.A N THR 182.A O no hydrogen 3.008 N/A HIS 186.A ND1 PRO 192.A O no hydrogen 2.728 N/A GLN 187.A N LEU 183.A O no hydrogen 2.835 N/A GLN 187.A NE2 GLU 203.A OE2 no hydrogen 2.952 N/A ILE 188.A N TYR 184.A O no hydrogen 2.938 N/A HIS 189.A N VAL 185.A O no hydrogen 3.268 N/A HIS 189.A N HIS 186.A O no hydrogen 3.171 N/A HIS 189.A NE2 ASP 12.A OD2 no hydrogen 2.725 N/A ASN 190.A N GLN 187.A O no hydrogen 3.057 N/A ALA 191.A N HIS 186.A O no hydrogen 2.777 N/A LEU 197.A N PRO 194.A O no hydrogen 3.234 N/A ILE 202.A N ALA 198.A O no hydrogen 2.959 N/A GLU 203.A N SER 199.A O no hydrogen 3.015 N/A THR 204.A N ASN 200.A O no hydrogen 2.954 N/A THR 204.A OG1 ASN 200.A O no hydrogen 3.028 N/A ILE 205.A N ASP 201.A O no hydrogen 2.793 N/A ILE 206.A N ILE 202.A O no hydrogen 2.987 N/A ASN 207.A N GLU 203.A O no hydrogen 2.884 N/A SER 208.A N THR 204.A O no hydrogen 2.819 N/A SER 208.A OG THR 204.A O no hydrogen 2.741 N/A ALA 209.A N ILE 205.A O no hydrogen 2.840 N/A GLU 210.A N ILE 206.A O no hydrogen 3.043 N/A TRP 211.A N ASN 207.A O no hydrogen 2.984 N/A ALA 212.A N SER 208.A O no hydrogen 2.826 N/A PHE 213.A N ALA 209.A O no hydrogen 2.908 N/A MET 214.A N GLU 210.A O no hydrogen 2.912 N/A ALA 215.A N TRP 211.A O no hydrogen 2.851 N/A GLN 216.A N ALA 212.A O no hydrogen 2.882 N/A GLN 216.A NE2 GLU 174.A OE2 no hydrogen 3.036 N/A GLU 217.A N PHE 213.A O no hydrogen 3.098 N/A LYS 218.A N ALA 215.A O no hydrogen 3.290 N/A GLN 220.A NE2 PHE 266.A O no hydrogen 3.033 N/A GLN 221.A N GLN 221.A OE1 no hydrogen 2.760 N/A ILE 222.A N PRO 219.A O no hydrogen 3.102 N/A ALA 223.A N PRO 219.A O no hydrogen 3.170 N/A ASN 224.A N GLN 220.A O no hydrogen 2.877 N/A TYR 226.A N ILE 222.A O no hydrogen 3.048 N/A SER 227.A N ALA 223.A O no hydrogen 2.715 N/A SER 227.A OG SER 262.A OG no hydrogen 2.618 N/A SER 228.A N ASN 224.A O no hydrogen 3.090 N/A SER 228.A OG ASN 224.A O no hydrogen 2.493 N/A LYS 229.A NZ ASP 122.A O no hydrogen 2.769 N/A LYS 229.A NZ ILE 126.A O no hydrogen 2.958 N/A MET 231.A N SER 227.A O no hydrogen 2.934 N/A THR 232.A N SER 228.A O no hydrogen 2.890 N/A THR 232.A OG1 SER 228.A O no hydrogen 2.671 N/A ASN 233.A N LYS 229.A O no hydrogen 3.014 N/A ASN 233.A ND2 GLU 123.A O no hydrogen 2.954 N/A ASN 233.A ND2 VAL 124.A O no hydrogen 2.958 N/A ILE 234.A N LEU 230.A O no hydrogen 2.911 N/A ALA 235.A N MET 231.A O no hydrogen 2.866 N/A ASP 236.A N THR 232.A O no hydrogen 2.921 N/A TYR 237.A N ASN 233.A O no hydrogen 2.830 N/A LEU 238.A N ILE 234.A O no hydrogen 3.034 N/A ASN 239.A N ALA 235.A O no hydrogen 2.790 N/A SER 240.A N ASP 236.A O no hydrogen 2.955 N/A SER 240.A OG ASP 236.A O no hydrogen 3.411 N/A GLY 241.A N TYR 237.A O no hydrogen 2.897 N/A SER 242.A N LEU 238.A O no hydrogen 3.118 N/A SER 242.A N ASN 239.A O no hydrogen 3.253 N/A SER 242.A OG ASN 239.A O no hydrogen 2.572 N/A MET 243.A N SER 240.A O no hydrogen 3.017 N/A LEU 248.A N SER 246.A OG no hydrogen 3.207 N/A LYS 249.A N THR 67.A O no hydrogen 2.861 N/A TYR 250.A N THR 67.A O no hydrogen 3.248 N/A TYR 250.A OH ASP 6.A OD2 no hydrogen 2.621 N/A VAL 251.A N ALA 4.A O no hydrogen 3.038 N/A LEU 252.A N TYR 69.A O no hydrogen 2.852 N/A LEU 253.A N ASP 6.A O no hydrogen 2.808 N/A SER 254.A N ARG 71.A O no hydrogen 2.737 N/A SER 254.A OG THR 78.A O no hydrogen 2.632 N/A ALA 255.A N ILE 8.A O no hydrogen 2.818 N/A HIS 256.A N THR 259.A OG1 no hydrogen 3.023 N/A HIS 256.A NE2 THR 73.A OG1 no hydrogen 2.822 N/A THR 259.A OG1 HIS 256.A O no hydrogen 3.395 N/A ILE 260.A N HIS 256.A O no hydrogen 3.215 N/A ALA 261.A N ASP 257.A O no hydrogen 2.959 N/A SER 262.A N THR 258.A O no hydrogen 2.924 N/A SER 262.A OG SER 227.A OG no hydrogen 2.618 N/A VAL 263.A N THR 259.A O no hydrogen 3.169 N/A LEU 264.A N ILE 260.A O no hydrogen 3.120 N/A SER 265.A N ALA 261.A O no hydrogen 2.992 N/A SER 265.A OG GLU 217.A O no hydrogen 2.851 N/A SER 265.A OG LYS 218.A O no hydrogen 2.960 N/A PHE 266.A N SER 262.A O no hydrogen 2.843 N/A LEU 267.A N VAL 263.A O no hydrogen 3.108 N/A GLY 268.A N SER 265.A O no hydrogen 2.942 N/A ALA 269.A N LEU 264.A O no hydrogen 2.905 N/A SER 274.A N GLU 210.A OE2 no hydrogen 2.806 N/A SER 274.A OG GLU 210.A OE2 no hydrogen 3.563 N/A ALA 278.A N HIS 10.A O no hydrogen 3.093 N/A SER 279.A OG PRO 276.A O no hydrogen 2.700 N/A ASN 280.A N ASN 300.A OD1 no hydrogen 2.651 N/A ASN 280.A ND2 ASP 6.A OD1 no hydrogen 3.055 N/A ASN 280.A ND2 ILE 7.A O no hydrogen 3.178 N/A VAL 281.A N ILE 7.A O no hydrogen 2.919 N/A ASN 282.A N THR 298.A O no hydrogen 2.724 N/A ASN 282.A ND2 ASP 6.A OD1 no hydrogen 2.597 N/A PHE 283.A N VAL 5.A O no hydrogen 2.750 N/A SER 284.A N LYS 296.A O no hydrogen 2.977 N/A SER 284.A OG ASN 282.A OD1 no hydrogen 2.653 N/A LEU 285.A N PHE 3.A O no hydrogen 2.819 N/A TYR 286.A N THR 294.A O no hydrogen 2.811 N/A ASN 288.A N TYR 292.A O no hydrogen 3.162 N/A GLY 289.A N ASP 287.A OD1 no hydrogen 2.867 N/A ALA 290.A N ASN 288.A OD1 no hydrogen 2.619 N/A TYR 292.A N ASN 288.A OD1 no hydrogen 3.122 N/A THR 294.A N TYR 286.A O no hydrogen 2.922 N/A VAL 295.A N CYS 314.A O no hydrogen 2.704 N/A LYS 296.A N SER 284.A O no hydrogen 2.890 N/A ILE 297.A N SER 312.A O no hydrogen 2.897 N/A THR 298.A N ASN 282.A O no hydrogen 2.929 N/A TYR 299.A N ASN 302.A O no hydrogen 2.768 N/A ASN 300.A N ASN 280.A O no hydrogen 2.866 N/A ASN 300.A ND2 SER 279.A OG no hydrogen 2.963 N/A ASN 302.A N TYR 299.A O no hydrogen 2.930 N/A VAL 304.A N ILE 297.A O no hydrogen 2.916 N/A ILE 306.A N GLY 311.A O no hydrogen 2.891 N/A CYS 309.A N ILE 306.A O no hydrogen 2.901 N/A GLY 310.A N PRO 307.A O no hydrogen 3.308 N/A GLY 311.A N ILE 306.A O no hydrogen 3.304 N/A CYS 314.A N VAL 295.A O no hydrogen 2.953 N/A GLU 315.A N GLN 318.A OE1 no hydrogen 2.930 N/A LEU 316.A N TYR 293.A O no hydrogen 2.875 N/A GLN 317.A N GLU 315.A OE2 no hydrogen 3.052 N/A GLN 317.A NE2 ASN 239.A OD1 no hydrogen 2.847 N/A GLN 318.A N GLU 315.A OE1 no hydrogen 2.955 N/A LEU 319.A N GLU 315.A O no hydrogen 2.959 N/A VAL 320.A N LEU 316.A O no hydrogen 2.915 N/A ASN 321.A N GLN 317.A O no hydrogen 2.788 N/A LEU 322.A N GLN 318.A O no hydrogen 2.975 N/A VAL 323.A N LEU 319.A O no hydrogen 2.952 N/A HIS 324.A N VAL 320.A O no hydrogen 2.983 N/A ASP 325.A N ASN 321.A O no hydrogen 2.788 N/A SER 326.A N VAL 323.A O no hydrogen 3.119 N/A