Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5cxq_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ALA 4.A N GLN 93.A OE1 no hydrogen 2.832 N/A ASN 8.A N ASN 5.A OD1 no hydrogen 2.764 N/A ASN 8.A ND2 VAL 3.A O no hydrogen 2.903 N/A ALA 9.A N ASN 5.A O no hydrogen 2.950 N/A SER 10.A N TYR 6.A O no hydrogen 2.936 N/A SER 10.A OG TYR 6.A O no hydrogen 2.739 N/A MET 11.A N GLU 7.A O no hydrogen 3.106 N/A ALA 12.A N ASN 8.A O no hydrogen 3.362 N/A ALA 13.A N ALA 9.A O no hydrogen 2.987 N/A ASP 14.A N SER 10.A O no hydrogen 2.927 N/A TYR 15.A N MET 11.A O no hydrogen 3.261 N/A ILE 16.A N ALA 12.A O no hydrogen 3.061 N/A LYS 17.A N ALA 13.A O no hydrogen 2.816 N/A ARG 18.A N ASP 14.A O no hydrogen 3.182 N/A ARG 18.A NE ASP 14.A OD2 no hydrogen 3.407 N/A VAL 19.A N TYR 15.A O no hydrogen 3.060 N/A SER 20.A N ILE 16.A O no hydrogen 2.966 N/A SER 20.A OG ILE 16.A O no hydrogen 2.930 N/A ASN 21.A N LYS 17.A O no hydrogen 3.176 N/A VAL 22.A N SER 20.A OG no hydrogen 3.180 N/A ASP 25.A N LYS 76.A O no hydrogen 2.951 N/A ILE 26.A N LYS 76.A O no hydrogen 3.415 N/A GLY 27.A N VAL 109.A O no hydrogen 2.856 N/A ILE 28.A N VAL 78.A O no hydrogen 2.932 N/A ILE 29.A N LEU 111.A O no hydrogen 2.980 N/A GLY 31.A N THR 113.A OG1 no hydrogen 2.921 N/A LEU 34.A N GLY 31.A O no hydrogen 2.966 N/A ILE 38.A N GLY 35.A O no hydrogen 3.132 N/A GLU 39.A N LYS 36.A O no hydrogen 2.725 N/A GLU 40.A N LEU 37.A O no hydrogen 2.911 N/A GLU 42.A N SER 71.A O no hydrogen 2.938 N/A LYS 45.A N LEU 69.A O no hydrogen 2.722 N/A LYS 45.A NZ.A GLU 43.A O no hydrogen 3.009 N/A LYS 45.A NZ.B VAL 46.A O no hydrogen 3.188 N/A ILE 47.A N LEU 67.A O no hydrogen 2.804 N/A TYR 49.A N GLY 65.A O no hydrogen 2.830 N/A TYR 49.A OH ASN 66.A O no hydrogen 3.397 N/A TYR 49.A OH GLY 82.A O no hydrogen 2.791 N/A ASN 51.A N PRO 48.A O no hydrogen 2.974 N/A ILE 52.A N TYR 49.A O no hydrogen 2.937 N/A ASN 54.A ND2 ASN 8.A O no hydrogen 3.023 N/A PHE 55.A N ILE 52.A O no hydrogen 3.129 N/A GLY 62.A N THR 58.A O no hydrogen 2.864 N/A ASN 66.A N GLN 81.A O no hydrogen 2.819 N/A ASN 66.A ND2 GLN 81.A OE1 no hydrogen 3.065 N/A LEU 67.A N ILE 47.A O no hydrogen 2.762 N/A VAL 68.A N ALA 79.A O no hydrogen 2.936 N/A LEU 69.A N LYS 45.A O no hydrogen 2.910 N/A GLY 70.A N ILE 77.A O no hydrogen 3.217 N/A SER 71.A N GLU 42.A O no hydrogen 2.914 N/A VAL 72.A N ARG 75.A O no hydrogen 2.834 N/A ARG 75.A N VAL 72.A O no hydrogen 2.833 N/A ARG 75.A NH1 PRO 282.A O no hydrogen 3.359 N/A ARG 75.A NH2 ASP 25.A OD2 no hydrogen 3.081 N/A ILE 77.A N GLY 70.A O no hydrogen 2.842 N/A VAL 78.A N ILE 26.A O no hydrogen 2.887 N/A ALA 79.A N VAL 68.A O no hydrogen 2.768 N/A MET 80.A N ILE 28.A O no hydrogen 3.070 N/A GLN 81.A N ASN 66.A O no hydrogen 2.758 N/A ARG 83.A NE GLU 223.A OE2 no hydrogen 3.174 N/A ARG 83.A NH1 CYS 30.A O no hydrogen 3.293 N/A ARG 83.A NH1 THR 113.A O no hydrogen 2.791 N/A ARG 83.A NH2 THR 220.A OG1 no hydrogen 2.993 N/A ARG 83.A NH2 GLU 223.A OE2 no hydrogen 3.360 N/A GLU 88.A N HIS 85.A O no hydrogen 3.057 N/A GLY 89.A N MET 86.A O no hydrogen 2.973 N/A SER 91.A N GLU 94.A OE1 no hydrogen 2.854 N/A ASN 92.A ND2 ASN 144.A O no hydrogen 3.055 N/A ASN 92.A ND2 VAL 147.A O no hydrogen 3.089 N/A GLN 93.A N SER 91.A OG no hydrogen 3.243 N/A GLU 94.A N SER 91.A OG no hydrogen 3.285 N/A ILE 95.A N SER 91.A O no hydrogen 3.072 N/A ALA 96.A N ASN 92.A O no hydrogen 3.064 N/A LEU 97.A N GLN 93.A O no hydrogen 3.172 N/A ARG 100.A N ALA 96.A O no hydrogen 3.090 N/A ARG 100.A NH1 ALA 4.A O no hydrogen 2.909 N/A ARG 100.A NH2 HIS 229.A ND1 no hydrogen 3.430 N/A VAL 101.A N LEU 97.A O no hydrogen 2.863 N/A MET 102.A N PRO 98.A O no hydrogen 3.015 N/A LYS 103.A N ILE 99.A O no hydrogen 2.981 N/A LYS 103.A NZ CYS 230.A O no hydrogen 2.859 N/A LEU 104.A N ARG 100.A O no hydrogen 3.042 N/A LEU 105.A N VAL 101.A O no hydrogen 2.871 N/A GLY 106.A N MET 102.A O no hydrogen 3.140 N/A GLY 106.A N LYS 103.A O no hydrogen 3.036 N/A VAL 107.A N MET 102.A O no hydrogen 2.979 N/A ARG 108.A N ASP 25.A O no hydrogen 2.881 N/A ARG 108.A NE ASP 284.A O no hydrogen 3.014 N/A LEU 110.A N LYS 233.A O no hydrogen 2.752 N/A LEU 111.A N GLY 27.A O no hydrogen 2.874 N/A ILE 112.A N LEU 235.A O no hydrogen 2.875 N/A THR 113.A N ILE 29.A O no hydrogen 3.072 N/A ASN 114.A N VAL 237.A O no hydrogen 3.104 N/A ASN 114.A ND2 THR 220.A OG1 no hydrogen 2.746 N/A ALA 116.A N LEU 239.A O no hydrogen 2.967 N/A GLY 117.A N VAL 216.A O no hydrogen 2.788 N/A GLY 118.A N ASN 242.A O no hydrogen 2.728 N/A ILE 119.A N ASP 214.A O no hydrogen 2.831 N/A ASN 120.A N ASP 214.A O no hydrogen 3.056 N/A ASN 120.A ND2 ASP 214.A OD1 no hydrogen 2.889 N/A LYS 122.A N ASN 120.A OD1 no hydrogen 2.838 N/A LEU 123.A N ASN 120.A O no hydrogen 3.098 N/A LYS 124.A N ASP 127.A OD2 no hydrogen 2.833 N/A SER 125.A OG ALA 241.A O no hydrogen 2.990 N/A GLY 126.A N ILE 240.A O no hydrogen 2.792 N/A ASP 127.A N LYS 124.A O no hydrogen 3.089 N/A PHE 128.A N LEU 185.A O no hydrogen 2.860 N/A VAL 129.A N SER 238.A O no hydrogen 2.802 N/A LEU 130.A N HIS 187.A O no hydrogen 2.797 N/A ILE 131.A N ALA 236.A O no hydrogen 2.952 N/A LYS 132.A N GLY 189.A O no hydrogen 2.967 N/A HIS 134.A ND1 TYR 165.A OH no hydrogen 2.822 N/A ILE 135.A N TYR 191.A O no hydrogen 2.910 N/A GLY 139.A N ASN 136.A OD1 no hydrogen 3.004 N/A LEU 140.A N ASN 136.A O no hydrogen 2.982 N/A GLY 141.A N PHE 137.A O no hydrogen 3.019 N/A LEU 142.A N GLY 139.A O no hydrogen 3.470 N/A ASN 143.A N PRO 138.A O no hydrogen 2.804 N/A LEU 146.A N ASN 144.A OD1 no hydrogen 2.922 N/A VAL 147.A N ASN 144.A O no hydrogen 3.017 N/A ASN 150.A ND2 ASP 152.A OD1 no hydrogen 2.861 N/A ASN 150.A ND2 GLY 155.A O no hydrogen 2.882 N/A GLU 153.A N GLU 153.A OE1 no hydrogen 2.778 N/A PHE 154.A N GLN 151.A O no hydrogen 3.027 N/A GLY 155.A N GLN 151.A O no hydrogen 3.392 N/A ARG 157.A NE ARG 157.A O no hydrogen 3.019 N/A ARG 157.A NH1 LEU 146.A O no hydrogen 3.143 N/A ARG 157.A NH1 GLY 148.A O no hydrogen 3.089 N/A ARG 157.A NH2 GLY 148.A O no hydrogen 2.888 N/A SER 162.A N ASP 160.A OD1 no hydrogen 2.913 N/A SER 162.A OG ASP 160.A OD1 no hydrogen 2.540 N/A ALA 164.A N LEU 161.A O no hydrogen 3.092 N/A TYR 165.A OH HIS 134.A ND1 no hydrogen 2.822 N/A ASP 166.A N VAL 234.A O no hydrogen 3.210 N/A LEU 169.A N ASP 166.A OD2 no hydrogen 2.909 N/A GLN 170.A N ASP 166.A O no hydrogen 3.184 N/A GLN 170.A NE2 TYR 165.A O no hydrogen 3.067 N/A GLN 170.A NE2 ASP 166.A O no hydrogen 3.472 N/A GLN 171.A N ARG 167.A O no hydrogen 2.996 N/A LEU 172.A N LEU 168.A O no hydrogen 2.946 N/A ALA 173.A N LEU 169.A O no hydrogen 3.004 N/A LEU 174.A N GLN 170.A O no hydrogen 3.051 N/A LYS 175.A N GLN 171.A O no hydrogen 2.956 N/A LYS 175.A NZ GLU 179.A OE2 no hydrogen 2.927 N/A ILE 176.A N LEU 172.A O no hydrogen 3.098 N/A ALA 177.A N ALA 173.A O no hydrogen 3.126 N/A GLN 178.A N LEU 174.A O no hydrogen 2.919 N/A GLU 179.A N LYS 175.A O no hydrogen 2.969 N/A ASN 180.A N ILE 176.A O no hydrogen 3.161 N/A ASN 180.A ND2 ILE 176.A O no hydrogen 2.927 N/A ASP 181.A N GLN 178.A O no hydrogen 3.187 N/A PHE 182.A N ALA 177.A O no hydrogen 2.997 N/A LEU 185.A N PHE 182.A O no hydrogen 2.989 N/A VAL 186.A N GLN 183.A O no hydrogen 3.006 N/A HIS 187.A N PHE 128.A O no hydrogen 2.894 N/A GLY 189.A N LEU 130.A O no hydrogen 3.064 N/A VAL 190.A N ASP 214.A OD2 no hydrogen 2.775 N/A TYR 191.A N GLY 133.A O no hydrogen 3.016 N/A TYR 191.A OH SER 219.A O no hydrogen 2.876 N/A ALA 192.A N VAL 215.A O no hydrogen 2.806 N/A PHE 193.A N ILE 135.A O no hydrogen 2.955 N/A ASN 194.A N GLY 217.A O no hydrogen 2.896 N/A ASN 194.A ND2 THR 198.A O no hydrogen 3.093 N/A GLY 196.A N ASN 194.A OD1 no hydrogen 3.203 N/A GLU 200.A N GLU 200.A OE1 no hydrogen 2.686 N/A SER 201.A N GLU 204.A OE1 no hydrogen 2.855 N/A GLU 204.A N SER 201.A OG no hydrogen 3.044 N/A SER 205.A N SER 201.A O no hydrogen 2.816 N/A SER 205.A OG SER 201.A O no hydrogen 3.273 N/A ASN 206.A N PRO 202.A O no hydrogen 3.084 N/A MET 207.A N ASP 203.A O no hydrogen 2.996 N/A LEU 208.A N GLU 204.A O no hydrogen 2.915 N/A LEU 209.A N SER 205.A O no hydrogen 3.059 N/A LYS 210.A N ASN 206.A O no hydrogen 3.237 N/A LEU 211.A N MET 207.A O no hydrogen 3.098 N/A LEU 211.A N LEU 208.A O no hydrogen 3.195 N/A GLY 212.A N LEU 209.A O no hydrogen 3.433 N/A CYS 213.A N LEU 208.A O no hydrogen 3.041 N/A ASP 214.A N VAL 190.A O no hydrogen 2.916 N/A VAL 215.A N VAL 190.A O no hydrogen 3.132 N/A VAL 216.A N GLY 117.A O no hydrogen 2.892 N/A GLY 217.A N ALA 192.A O no hydrogen 3.032 N/A SER 219.A N TYR 191.A OH no hydrogen 3.148 N/A SER 219.A OG THR 220.A OG1 no hydrogen 3.057 N/A THR 220.A OG1 SER 219.A OG no hydrogen 3.057 N/A VAL 221.A N SER 219.A O no hydrogen 2.854 N/A GLU 223.A N GLU 223.A OE1 no hydrogen 2.816 N/A VAL 224.A N THR 220.A O no hydrogen 2.919 N/A ILE 225.A N VAL 221.A O no hydrogen 2.971 N/A ILE 226.A N PRO 222.A O no hydrogen 3.091 N/A ALA 227.A N GLU 223.A O no hydrogen 2.932 N/A CYS 228.A N VAL 224.A O no hydrogen 2.833 N/A CYS 228.A SG ASP 160.A O no hydrogen 3.761 N/A HIS 229.A N ILE 225.A O no hydrogen 2.929 N/A HIS 229.A NE2 ASN 150.A OD1 no hydrogen 2.938 N/A CYS 230.A N ILE 226.A O no hydrogen 3.258 N/A CYS 230.A SG ILE 226.A O no hydrogen 3.499 N/A CYS 230.A SG ALA 227.A O no hydrogen 3.695 N/A GLY 231.A N CYS 228.A O no hydrogen 3.172 N/A ILE 232.A N ALA 227.A O no hydrogen 2.911 N/A LYS 233.A N ARG 108.A O no hydrogen 3.057 N/A LEU 235.A N LEU 110.A O no hydrogen 3.037 N/A VAL 237.A N ILE 112.A O no hydrogen 2.946 N/A SER 238.A N VAL 129.A O no hydrogen 2.905 N/A SER 238.A OG ASN 114.A OD1 no hydrogen 2.696 N/A LEU 239.A N ASN 114.A O no hydrogen 2.811 N/A ILE 240.A N ASP 127.A O no hydrogen 2.847 N/A ALA 241.A N ALA 116.A O no hydrogen 2.889 N/A ASN 242.A ND2 SER 244.A OG no hydrogen 3.267 N/A ASN 242.A ND2 ASP 247.A OD2 no hydrogen 2.970 N/A ASN 243.A ND2 ASN 120.A O no hydrogen 3.028 N/A ASN 243.A ND2 LEU 123.A O no hydrogen 2.966 N/A SER 244.A N GLY 118.A O no hydrogen 2.781 N/A SER 244.A OG GLU 200.A OE2 no hydrogen 2.544 N/A LEU 246.A N ASN 243.A OD1 no hydrogen 2.935 N/A ASP 247.A N ASN 243.A O no hydrogen 2.929 N/A ALA 248.A N SER 244.A O no hydrogen 2.948 N/A GLU 249.A N ILE 245.A O no hydrogen 3.031 N/A ASN 250.A N LEU 246.A O no hydrogen 3.005 N/A ASN 250.A N ASP 247.A O no hydrogen 3.256 N/A ASP 251.A N ALA 248.A O no hydrogen 3.347 N/A VAL 252.A N ASP 247.A O no hydrogen 2.868 N/A GLU 257.A N GLU 257.A OE1 no hydrogen 2.686 N/A LYS 258.A N ASN 255.A OD1 no hydrogen 2.709 N/A LYS 258.A NZ SER 253.A O no hydrogen 2.975 N/A VAL 259.A N ASN 255.A O no hydrogen 3.128 N/A LEU 260.A N HIS 256.A O no hydrogen 2.837 N/A ALA 261.A N GLU 257.A O no hydrogen 3.073 N/A VAL 262.A N LYS 258.A O no hydrogen 3.224 N/A ALA 263.A N VAL 259.A O no hydrogen 3.069 N/A GLU 264.A N LEU 260.A O no hydrogen 2.973 N/A LYS 265.A N ALA 261.A O no hydrogen 3.079 N/A ARG 266.A N VAL 262.A O no hydrogen 3.113 N/A ARG 266.A N ALA 263.A O no hydrogen 3.214 N/A ARG 266.A NE GLY 126.A O no hydrogen 2.806 N/A LEU 270.A N ARG 266.A O no hydrogen 2.976 N/A GLN 271.A N ALA 267.A O no hydrogen 2.978 N/A MET 272.A N ASP 268.A O no hydrogen 3.047 N/A TRP 273.A N LEU 269.A O no hydrogen 2.954 N/A TRP 273.A NE1 ALA 173.A O no hydrogen 2.931 N/A PHE 274.A N LEU 270.A O no hydrogen 2.988 N/A LYS 275.A N GLN 271.A O no hydrogen 2.945 N/A LYS 275.A NZ GLU 40.A OE1 no hydrogen 2.903 N/A GLU 276.A N MET 272.A O no hydrogen 3.114 N/A ILE 277.A N TRP 273.A O no hydrogen 2.957 N/A ILE 278.A N PHE 274.A O no hydrogen 2.921 N/A THR 279.A N LYS 275.A O no hydrogen 3.047 N/A THR 279.A OG1 LYS 275.A O no hydrogen 2.990 N/A ARG 280.A N GLU 276.A O no hydrogen 2.943 N/A ARG 280.A N ILE 277.A O no hydrogen 2.983 N/A ARG 280.A NH1 GLU 179.A OE1 no hydrogen 2.892 N/A ARG 280.A NH1 GLU 276.A OE2 no hydrogen 3.190 N/A ARG 280.A NH2 GLU 179.A OE1 no hydrogen 3.566 N/A ARG 280.A NH2 GLU 179.A OE2 no hydrogen 2.954 N/A LEU 281.A N ILE 278.A O no hydrogen 3.350 N/A