Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5cxy_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 5.A N GLY 282.A O no hydrogen 2.952 N/A ALA 8.A N ASN 5.A OD1 no hydrogen 3.083 N/A PHE 9.A N ASN 5.A O no hydrogen 2.896 N/A LEU 10.A N ARG 6.A O no hydrogen 2.891 N/A HIS 11.A N THR 7.A O no hydrogen 3.063 N/A GLN 12.A N ALA 8.A O no hydrogen 2.952 N/A GLN 12.A NE2 TYR 200.A OH no hydrogen 3.186 N/A ARG 13.A N PHE 9.A O no hydrogen 2.758 N/A ARG 13.A NE SER 222.A O no hydrogen 2.886 N/A ARG 13.A NH2 CYS 225.A O no hydrogen 2.868 N/A ARG 13.A NH2 GLU 226.A OE1 no hydrogen 3.027 N/A GLN 14.A N LEU 10.A O no hydrogen 3.002 N/A GLU 15.A N HIS 11.A O no hydrogen 2.965 N/A ILE 16.A N GLN 12.A O no hydrogen 2.788 N/A LEU 17.A N ARG 13.A O no hydrogen 2.821 N/A GLN 18.A N GLN 14.A O no hydrogen 3.048 N/A GLN 18.A N GLU 15.A O no hydrogen 3.294 N/A HIS 19.A N ILE 16.A O no hydrogen 2.941 N/A HIS 19.A ND1 GLU 15.A O no hydrogen 2.878 N/A VAL 20.A N ILE 16.A O no hydrogen 2.795 N/A LYS 24.A N ASP 21.A OD1 no hydrogen 3.209 N/A ASN 25.A N ASP 21.A O no hydrogen 2.839 N/A PHE 26.A N VAL 22.A O no hydrogen 2.847 N/A SER 27.A N LYS 24.A O no hydrogen 3.366 N/A SER 27.A OG LEU 28.A O no hydrogen 2.671 N/A LEU 28.A N TRP 189.A O no hydrogen 2.847 N/A THR 29.A N SER 32.A OG no hydrogen 2.990 N/A THR 29.A OG1 SER 32.A OG no hydrogen 3.406 N/A LYS 30.A N PRO 61.A O no hydrogen 3.048 N/A LYS 30.A NZ LEU 60.A O no hydrogen 2.862 N/A LYS 30.A NZ ASP 62.A OD1 no hydrogen 2.981 N/A SER 32.A N THR 29.A O no hydrogen 3.008 N/A SER 32.A OG THR 29.A O no hydrogen 3.025 N/A SER 32.A OG THR 29.A OG1 no hydrogen 3.406 N/A VAL 33.A N LYS 30.A O no hydrogen 3.458 N/A ARG 34.A N GLN 37.A OE1 no hydrogen 2.884 N/A GLY 36.A N ILE 52.A O no hydrogen 2.822 N/A GLN 37.A N ARG 34.A O no hydrogen 3.072 N/A MET 39.A N PHE 50.A O no hydrogen 2.847 N/A HIS 40.A ND1 HIS 46.A O no hydrogen 2.715 N/A ASP 42.A N PHE 160.A O no hydrogen 2.919 N/A TYR 43.A N PHE 161.A O no hydrogen 2.823 N/A SER 44.A OG HIS 163.A ND1 no hydrogen 3.164 N/A LYS 47.A N SER 45.A OG no hydrogen 3.423 N/A TYR 48.A N SER 45.A O no hydrogen 3.270 N/A PHE 50.A N MET 39.A O no hydrogen 3.004 N/A ILE 52.A N GLN 37.A O no hydrogen 2.820 N/A ASN 55.A N ASN 54.A OD1 no hydrogen 2.835 N/A PHE 56.A N SER 53.A OG no hydrogen 2.952 N/A ARG 57.A N SER 53.A O no hydrogen 3.022 N/A ARG 57.A NE LYS 30.A O no hydrogen 3.027 N/A ARG 57.A NE VAL 33.A O no hydrogen 3.523 N/A SER 58.A N ASN 54.A O no hydrogen 2.946 N/A SER 58.A OG ASN 55.A O no hydrogen 2.651 N/A LEU 59.A N PHE 56.A O no hydrogen 2.905 N/A LEU 60.A N ARG 57.A O no hydrogen 3.078 N/A SER 64.A OG ILE 23.A O no hydrogen 2.718 N/A ILE 66.A N SER 64.A OG no hydrogen 3.291 N/A MET 67.A N SER 64.A O no hydrogen 3.147 N/A LYS 69.A N ILE 66.A O no hydrogen 3.217 N/A TYR 71.A N ILE 224.A O no hydrogen 2.881 N/A ILE 73.A N ASP 96.A OD2 no hydrogen 2.927 N/A CYS 74.A N GLU 227.A O no hydrogen 2.853 N/A ALA 75.A N PHE 97.A O no hydrogen 2.992 N/A VAL 76.A N HIS 229.A O no hydrogen 3.013 N/A VAL 77.A N PHE 99.A O no hydrogen 2.833 N/A GLY 78.A N TYR 231.A O no hydrogen 2.757 N/A ASN 79.A ND2 CYS 101.A O no hydrogen 3.159 N/A SER 80.A N GLY 232.A O no hydrogen 3.012 N/A SER 80.A OG TRP 234.A O no hydrogen 2.808 N/A GLY 81.A N TYR 248.A O no hydrogen 3.196 N/A ILE 82.A N SER 80.A OG no hydrogen 3.078 N/A LEU 83.A N SER 80.A O no hydrogen 3.208 N/A THR 84.A N GLY 81.A O no hydrogen 2.862 N/A THR 84.A OG1 GLY 81.A O no hydrogen 3.388 N/A THR 84.A OG1 TYR 250.A O no hydrogen 3.117 N/A GLY 85.A N ASP 112.A OD2 no hydrogen 2.780 N/A SER 86.A N LEU 83.A O no hydrogen 3.035 N/A SER 86.A OG LEU 83.A O no hydrogen 2.808 N/A GLN 87.A N ASP 112.A OD1 no hydrogen 2.889 N/A CYS 88.A N SER 86.A OG no hydrogen 3.195 N/A CYS 88.A SG SER 86.A O no hydrogen 3.700 N/A CYS 88.A SG SER 86.A OG no hydrogen 3.351 N/A CYS 88.A SG SER 289.A O no hydrogen 3.973 N/A GLY 89.A N ARG 111.A O no hydrogen 2.804 N/A ILE 92.A N CYS 88.A O no hydrogen 2.879 N/A ASP 93.A N GLY 89.A O no hydrogen 2.949 N/A LYS 94.A N GLN 90.A O no hydrogen 3.101 N/A SER 95.A N ILE 92.A O no hydrogen 3.126 N/A SER 95.A OG ILE 92.A O no hydrogen 2.516 N/A ASP 96.A N ILE 73.A O no hydrogen 2.715 N/A PHE 97.A N ILE 73.A O no hydrogen 3.372 N/A VAL 98.A N ASN 118.A OD1 no hydrogen 2.828 N/A PHE 99.A N ALA 75.A O no hydrogen 2.856 N/A ARG 100.A N LEU 119.A O no hydrogen 2.855 N/A ARG 100.A NE LYS 116.A O no hydrogen 2.957 N/A ARG 100.A NE THR 117.A OG1 no hydrogen 2.923 N/A ARG 100.A NH1 VAL 113.A O no hydrogen 2.858 N/A ARG 100.A NH1 LYS 116.A O no hydrogen 2.700 N/A ARG 100.A NH2 VAL 113.A O no hydrogen 2.837 N/A CYS 101.A SG VAL 77.A O no hydrogen 3.628 N/A ASN 102.A N THR 121.A OG1 no hydrogen 2.791 N/A ALA 104.A N CYS 101.A O no hydrogen 3.186 N/A PHE 109.A N THR 106.A O no hydrogen 3.021 N/A GLN 110.A NE2 GLU 107.A OE1 no hydrogen 3.238 N/A ASP 112.A N PHE 109.A O no hydrogen 2.951 N/A VAL 113.A N PHE 109.A O no hydrogen 2.916 N/A GLY 114.A N GLN 110.A O no hydrogen 2.835 N/A ARG 115.A N ASP 93.A OD1 no hydrogen 3.231 N/A ARG 115.A N ASP 93.A OD2 no hydrogen 2.875 N/A LYS 116.A N ASP 93.A OD1 no hydrogen 2.985 N/A LYS 116.A NZ ASP 93.A O no hydrogen 2.910 N/A LYS 116.A NZ SER 95.A O no hydrogen 2.899 N/A ASN 118.A N VAL 98.A O no hydrogen 2.911 N/A LEU 119.A N VAL 98.A O no hydrogen 3.094 N/A THR 120.A N ILE 154.A O no hydrogen 3.003 N/A THR 121.A N ARG 100.A O no hydrogen 3.206 N/A THR 121.A OG1 ASN 102.A OD1 no hydrogen 3.497 N/A PHE 122.A N TRP 156.A O no hydrogen 2.899 N/A SER 125.A N ASN 123.A OD1 no hydrogen 2.923 N/A SER 125.A OG ASN 123.A OD1 no hydrogen 2.550 N/A ILE 126.A N ASN 123.A O no hydrogen 2.981 N/A LEU 127.A N PRO 124.A O no hydrogen 2.957 N/A GLU 128.A N SER 125.A O no hydrogen 3.020 N/A LYS 129.A N SER 125.A O no hydrogen 3.079 N/A TYR 130.A N ILE 126.A O no hydrogen 2.880 N/A TYR 131.A N LEU 127.A O no hydrogen 3.159 N/A TYR 131.A OH SER 146.A OG no hydrogen 2.912 N/A ASN 132.A ND2 ASP 139.A OD2 no hydrogen 2.860 N/A ASN 133.A N LEU 127.A O no hydrogen 2.908 N/A LEU 134.A N TYR 131.A O no hydrogen 2.915 N/A LEU 135.A N ASN 132.A O no hydrogen 3.140 N/A THR 136.A N ASP 139.A OD2 no hydrogen 3.344 N/A THR 136.A OG1 ASP 139.A OD2 no hydrogen 2.620 N/A ASP 139.A N THR 136.A OG1 no hydrogen 3.085 N/A ARG 140.A N THR 136.A O no hydrogen 3.030 N/A ARG 140.A NH1 GLU 178.A OE1 no hydrogen 2.761 N/A ARG 140.A NH1 GLU 178.A OE2 no hydrogen 3.454 N/A ARG 140.A NH2 GLU 178.A OE1 no hydrogen 3.478 N/A ARG 140.A NH2 GLU 178.A OE2 no hydrogen 2.690 N/A ASN 141.A N ILE 137.A O no hydrogen 2.885 N/A ASN 142.A N GLN 138.A O no hydrogen 2.751 N/A PHE 143.A N ASP 139.A O no hydrogen 2.919 N/A PHE 144.A N ARG 140.A O no hydrogen 2.912 N/A LEU 145.A N ASN 141.A O no hydrogen 3.005 N/A SER 146.A N ASN 142.A O no hydrogen 3.067 N/A SER 146.A OG TYR 131.A OH no hydrogen 2.912 N/A SER 146.A OG ASN 142.A O no hydrogen 2.983 N/A LEU 147.A N PHE 143.A O no hydrogen 2.911 N/A LYS 148.A N PHE 144.A O no hydrogen 2.893 N/A LYS 149.A N LEU 145.A O no hydrogen 3.026 N/A LYS 149.A NZ GLU 107.A OE2 no hydrogen 2.846 N/A LEU 150.A N LEU 147.A O no hydrogen 2.973 N/A ASP 151.A N LYS 148.A O no hydrogen 3.037 N/A ALA 153.A N LEU 150.A O no hydrogen 2.972 N/A ILE 154.A N ASN 118.A O no hydrogen 2.954 N/A LEU 155.A N GLN 186.A O no hydrogen 2.868 N/A TRP 156.A N THR 120.A O no hydrogen 2.934 N/A TRP 156.A NE1 PHE 26.A O no hydrogen 2.845 N/A ILE 157.A N ALA 188.A O no hydrogen 2.862 N/A HIS 163.A N SER 44.A OG no hydrogen 2.980 N/A HIS 163.A ND1 SER 44.A OG no hydrogen 3.164 N/A SER 165.A N PHE 162.A O no hydrogen 2.855 N/A SER 165.A OG PHE 162.A O no hydrogen 3.117 N/A ALA 166.A N HIS 163.A O no hydrogen 3.059 N/A THR 169.A N SER 165.A O no hydrogen 2.843 N/A THR 169.A OG1 SER 165.A O no hydrogen 2.630 N/A ARG 170.A N THR 167.A O no hydrogen 3.043 N/A THR 171.A N THR 167.A O no hydrogen 3.457 N/A LEU 172.A N VAL 168.A O no hydrogen 2.922 N/A VAL 173.A N THR 169.A O no hydrogen 2.855 N/A ASP 174.A N ARG 170.A O no hydrogen 2.889 N/A PHE 175.A N THR 171.A O no hydrogen 3.009 N/A PHE 176.A N LEU 172.A O no hydrogen 2.975 N/A VAL 177.A N VAL 173.A O no hydrogen 2.900 N/A GLU 178.A N ASP 174.A O no hydrogen 2.845 N/A HIS 179.A N PHE 175.A O no hydrogen 2.985 N/A HIS 179.A ND1 PHE 175.A O no hydrogen 2.736 N/A ARG 180.A N VAL 177.A O no hydrogen 3.138 N/A ARG 180.A NH2 SER 58.A O no hydrogen 3.006 N/A ARG 180.A NH2 SER 58.A OG no hydrogen 2.493 N/A GLN 182.A N HIS 179.A O no hydrogen 3.037 N/A GLN 186.A N ALA 153.A O no hydrogen 2.959 N/A GLN 186.A NE2 GLY 152.A O no hydrogen 3.073 N/A ALA 188.A N LEU 155.A O no hydrogen 2.980 N/A TRP 189.A N SER 27.A OG no hydrogen 2.954 N/A ASN 192.A ND2 HIS 40.A O no hydrogen 2.956 N/A ASN 192.A ND2 ASP 42.A OD1 no hydrogen 2.792 N/A MET 194.A N ASP 42.A OD2 no hydrogen 2.992 N/A HIS 196.A N ILE 193.A O no hydrogen 3.003 N/A VAL 197.A N ILE 193.A O no hydrogen 3.078 N/A ASN 198.A N MET 194.A O no hydrogen 2.759 N/A ARG 199.A N HIS 196.A O no hydrogen 3.238 N/A TRP 201.A NE1 THR 219.A OG1 no hydrogen 3.020 N/A LYS 202.A N ASN 198.A O no hydrogen 2.849 N/A LYS 204.A N TRP 201.A O no hydrogen 3.105 N/A LYS 204.A NZ GLU 15.A OE1 no hydrogen 3.238 N/A HIS 205.A N LYS 202.A O no hydrogen 2.824 N/A SER 212.A N GLU 271.A OE2 no hydrogen 2.751 N/A SER 212.A OG GLU 271.A OE1 no hydrogen 2.503 N/A ILE 215.A N SER 212.A OG no hydrogen 3.367 N/A LEU 216.A N SER 212.A O no hydrogen 3.069 N/A MET 217.A N THR 213.A O no hydrogen 2.855 N/A TYR 218.A N GLY 214.A O no hydrogen 3.073 N/A TYR 218.A OH GLN 12.A OE1 no hydrogen 2.456 N/A THR 219.A N ILE 215.A O no hydrogen 3.020 N/A THR 219.A OG1 ILE 215.A O no hydrogen 2.741 N/A LEU 220.A N LEU 216.A O no hydrogen 3.062 N/A ALA 221.A N MET 217.A O no hydrogen 2.785 N/A SER 222.A N TYR 218.A O no hydrogen 2.915 N/A SER 222.A OG THR 219.A O no hydrogen 2.591 N/A ALA 223.A N LEU 220.A O no hydrogen 3.045 N/A ILE 224.A N ALA 221.A O no hydrogen 3.092 N/A CYS 225.A N ALA 221.A O no hydrogen 2.868 N/A GLU 226.A N TYR 71.A O no hydrogen 2.869 N/A GLU 227.A N ASN 72.A O no hydrogen 2.864 N/A HIS 229.A N CYS 74.A O no hydrogen 2.792 N/A HIS 229.A NE2 GLU 227.A OE2 no hydrogen 2.872 N/A LEU 230.A N LYS 285.A O no hydrogen 2.719 N/A TYR 231.A N VAL 76.A O no hydrogen 3.021 N/A TYR 231.A OH GLU 91.A OE1 no hydrogen 2.664 N/A TRP 234.A NE1 PHE 238.A O no hydrogen 2.852 N/A ASP 239.A N GLU 244.A O no hydrogen 2.822 N/A ASN 241.A N ASP 239.A OD2 no hydrogen 2.809 N/A ASN 241.A ND2 LEU 288.A O no hydrogen 3.142 N/A THR 242.A N ASP 239.A OD2 no hydrogen 2.987 N/A ARG 243.A N ASP 239.A O no hydrogen 2.907 N/A GLU 244.A N THR 242.A OG1 no hydrogen 3.098 N/A LEU 246.A N GLY 237.A O no hydrogen 2.651 N/A HIS 249.A N ASP 252.A OD2 no hydrogen 3.066 N/A TYR 250.A N ASN 79.A O no hydrogen 2.938 N/A TYR 250.A OH PRO 105.A O no hydrogen 2.570 N/A ASP 252.A N HIS 249.A O no hydrogen 3.189 N/A THR 256.A N LYS 253.A O no hydrogen 3.019 N/A THR 256.A OG1 LYS 253.A O no hydrogen 2.502 N/A GLN 263.A NE2 GLN 263.A O no hydrogen 3.082 N/A HIS 266.A N GLN 263.A O no hydrogen 3.366 N/A GLU 271.A N GLN 267.A O no hydrogen 3.028 N/A PHE 272.A N LEU 268.A O no hydrogen 2.753 N/A GLN 273.A N PRO 269.A O no hydrogen 2.906 N/A LEU 274.A N ALA 270.A O no hydrogen 2.962 N/A LEU 275.A N GLU 271.A O no hydrogen 2.857 N/A TYR 276.A N PHE 272.A O no hydrogen 2.789 N/A ARG 277.A N GLN 273.A O no hydrogen 2.967 N/A MET 278.A N LEU 274.A O no hydrogen 3.020 N/A HIS 279.A N LEU 275.A O no hydrogen 2.819 N/A GLY 280.A N TYR 276.A O no hydrogen 3.078 N/A GLU 281.A N ARG 277.A O no hydrogen 2.889 N/A GLY 282.A N HIS 279.A O no hydrogen 3.021 N/A LEU 283.A N MET 278.A O no hydrogen 2.929 N/A THR 284.A OG1 ILE 228.A O no hydrogen 2.631 N/A LYS 285.A N ILE 228.A O no hydrogen 3.282 N/A LEU 286.A N HIS 279.A ND1 no hydrogen 3.053 N/A THR 287.A N LEU 230.A O no hydrogen 2.979 N/A CYS 291.A N SER 86.A O no hydrogen 2.811 N/A CYS 291.A SG GLU 91.A OE2 no hydrogen 3.462 N/A