Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5czo_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 5.A NE ASP 3.A OD1 no hydrogen 2.942 N/A ARG 5.A NH2 ASP 3.A OD2 no hydrogen 3.079 N/A VAL 6.A N PHE 9.A O no hydrogen 2.773 N/A GLY 7.A N GLU 74.A OE2 no hydrogen 3.177 N/A ARG 10.A N THR 27.A O no hydrogen 2.980 N/A ILE 11.A N LEU 4.A O no hydrogen 2.856 N/A GLY 12.A N HIS 25.A O no hydrogen 2.656 N/A ILE 15.A N ILE 23.A O no hydrogen 2.997 N/A GLY 16.A N ILE 23.A O no hydrogen 3.125 N/A GLY 21.A N GLY 18.A O no hydrogen 3.191 N/A ASP 22.A N LEU 39.A O no hydrogen 3.201 N/A ILE 23.A N GLY 16.A O no hydrogen 2.564 N/A TYR 24.A N ILE 37.A O no hydrogen 2.738 N/A HIS 25.A N ARG 13.A O no hydrogen 2.892 N/A HIS 25.A NE2 GLU 34.A OE2 no hydrogen 2.848 N/A GLY 26.A N VAL 35.A O no hydrogen 2.748 N/A THR 27.A N ARG 10.A O no hydrogen 3.259 N/A ASN 28.A N GLU 33.A O no hydrogen 2.827 N/A ILE 30.A N ASN 28.A OD1 no hydrogen 2.863 N/A SER 31.A N ASN 28.A OD1 no hydrogen 3.446 N/A SER 31.A OG GLU 33.A OE1 no hydrogen 2.787 N/A GLY 32.A N ASN 28.A O no hydrogen 3.004 N/A VAL 35.A N GLY 26.A O no hydrogen 2.638 N/A ALA 36.A N ILE 82.A O no hydrogen 2.608 N/A ILE 37.A N TYR 24.A O no hydrogen 2.656 N/A ARG 38.A N MET 80.A O no hydrogen 2.680 N/A LEU 39.A N ASP 22.A O no hydrogen 2.863 N/A GLU 40.A N ASN 78.A O no hydrogen 2.874 N/A SER 41.A OG GLU 76.A OE2 no hydrogen 3.119 N/A ILE 42.A N GLU 76.A O no hydrogen 3.273 N/A ARG 43.A N SER 41.A OG no hydrogen 3.427 N/A SER 44.A OG SER 41.A O no hydrogen 3.166 N/A GLN 48.A N GLU 40.A OE2 no hydrogen 3.222 N/A LEU 49.A N GLU 40.A OE1 no hydrogen 3.402 N/A TYR 51.A OH SER 153.A O no hydrogen 2.605 N/A GLU 52.A N GLN 48.A O no hydrogen 2.965 N/A SER 53.A N LEU 49.A O no hydrogen 3.078 N/A ARG 54.A N ASP 50.A O no hydrogen 3.310 N/A ARG 54.A N TYR 51.A O no hydrogen 2.968 N/A VAL 55.A N TYR 51.A O no hydrogen 3.181 N/A TYR 56.A N GLU 52.A O no hydrogen 2.847 N/A ARG 57.A N SER 53.A O no hydrogen 3.434 N/A TYR 58.A N ARG 54.A O no hydrogen 3.092 N/A LEU 59.A N VAL 55.A O no hydrogen 2.796 N/A ILE 65.A N GLY 62.A O no hydrogen 3.287 N/A ARG 69.A N VAL 81.A O no hydrogen 2.660 N/A TRP 70.A N VAL 81.A O no hydrogen 3.246 N/A GLY 72.A N ALA 79.A O no hydrogen 3.154 N/A ARG 73.A NE GLY 75.A O no hydrogen 3.066 N/A ARG 73.A NH2 GLY 75.A O no hydrogen 3.148 N/A GLU 74.A N TYR 77.A O no hydrogen 2.765 N/A TYR 77.A N GLU 74.A O no hydrogen 3.080 N/A ASN 78.A N GLU 40.A O no hydrogen 2.582 N/A ALA 79.A N GLY 72.A O no hydrogen 2.785 N/A MET 80.A N ARG 38.A O no hydrogen 2.844 N/A VAL 81.A N TRP 70.A O no hydrogen 2.780 N/A ILE 82.A N ALA 36.A O no hydrogen 2.859 N/A LEU 84.A N GLU 34.A O no hydrogen 3.362 N/A GLY 86.A N MET 136.A O no hydrogen 2.505 N/A SER 88.A N ASP 91.A OD2 no hydrogen 3.132 N/A LEU 89.A N PHE 134.A O no hydrogen 3.011 N/A ASP 91.A N SER 88.A OG no hydrogen 3.181 N/A LEU 92.A N SER 88.A O no hydrogen 2.991 N/A PHE 93.A N LEU 89.A O no hydrogen 2.706 N/A ASN 94.A N GLU 90.A O no hydrogen 3.128 N/A TYR 95.A N ASP 91.A O no hydrogen 2.981 N/A CYS 96.A N LEU 92.A O no hydrogen 3.093 N/A CYS 96.A N PHE 93.A O no hydrogen 3.222 N/A CYS 96.A SG LEU 92.A O no hydrogen 3.385 N/A HIS 97.A N ASN 94.A O no hydrogen 3.219 N/A ARG 98.A N PHE 93.A O no hydrogen 2.557 N/A ARG 98.A NH1 TYR 201.A OH no hydrogen 2.623 N/A PHE 100.A N PHE 202.A O no hydrogen 3.383 N/A SER 101.A N ASP 282.A OD2 no hydrogen 2.698 N/A SER 101.A OG THR 104.A OG1 no hydrogen 3.018 N/A SER 101.A OG ASP 282.A OD1 no hydrogen 2.539 N/A SER 101.A OG ASP 282.A OD2 no hydrogen 3.026 N/A PHE 102.A N HIS 327.A O no hydrogen 2.725 N/A LYS 103.A NZ ASP 278.A OD1 no hydrogen 3.061 N/A LYS 103.A NZ LEU 280.A O no hydrogen 2.577 N/A THR 104.A N SER 101.A OG no hydrogen 3.253 N/A THR 104.A OG1 SER 101.A OG no hydrogen 3.018 N/A THR 104.A OG1 ASP 282.A OD1 no hydrogen 2.824 N/A VAL 105.A N SER 101.A O no hydrogen 3.152 N/A ILE 106.A N PHE 102.A O no hydrogen 3.167 N/A MET 107.A N LYS 103.A O no hydrogen 2.944 N/A LEU 108.A N THR 104.A O no hydrogen 2.757 N/A ALA 109.A N VAL 105.A O no hydrogen 2.772 N/A LEU 110.A N ILE 106.A O no hydrogen 3.016 N/A GLN 111.A NE2 SER 143.A O no hydrogen 2.808 N/A MET 112.A N LEU 108.A O no hydrogen 2.967 N/A PHE 113.A N ALA 109.A O no hydrogen 2.970 N/A CYS 114.A SG LEU 110.A O no hydrogen 3.644 N/A ARG 115.A N GLN 111.A O no hydrogen 3.221 N/A ARG 115.A NE VAL 145.A O no hydrogen 2.799 N/A ILE 116.A N MET 112.A O no hydrogen 2.977 N/A GLN 117.A N PHE 113.A O no hydrogen 3.018 N/A TYR 118.A N CYS 114.A O no hydrogen 2.967 N/A TYR 118.A OH LEU 59.A O no hydrogen 2.976 N/A ILE 119.A N ARG 115.A O no hydrogen 3.197 N/A HIS 120.A N ILE 116.A O no hydrogen 2.931 N/A HIS 120.A ND1 TYR 259.A OH no hydrogen 2.921 N/A HIS 120.A NE2 ASP 191.A OD2 no hydrogen 3.169 N/A GLY 121.A N GLN 117.A O no hydrogen 2.767 N/A ARG 122.A N ILE 119.A O no hydrogen 3.208 N/A ARG 122.A NH2 TYR 58.A O no hydrogen 2.776 N/A SER 123.A N HIS 120.A O no hydrogen 3.081 N/A PHE 124.A N ILE 119.A O no hydrogen 3.083 N/A HIS 126.A N ASP 191.A OD2 no hydrogen 2.911 N/A HIS 126.A NE2 ILE 148.A O no hydrogen 3.041 N/A ARG 127.A N ASP 191.A OD1 no hydrogen 3.359 N/A ARG 127.A NE LEU 152.A O no hydrogen 3.009 N/A ASN 133.A N LYS 130.A O no hydrogen 2.931 N/A ASN 133.A ND2 ASP 128.A O no hydrogen 2.470 N/A ASN 133.A ND2 ASP 128.A OD2 no hydrogen 3.446 N/A PHE 134.A N PRO 131.A O no hydrogen 3.414 N/A LEU 135.A N HIS 146.A O no hydrogen 2.969 N/A MET 136.A N PRO 87.A O no hydrogen 3.186 N/A ARG 141.A N VAL 138.A O no hydrogen 3.310 N/A GLY 142.A N GLY 139.A O no hydrogen 3.297 N/A THR 144.A N ARG 141.A O no hydrogen 3.011 N/A VAL 145.A N GLN 111.A OE1 no hydrogen 2.767 N/A HIS 146.A N LEU 135.A O no hydrogen 2.529 N/A VAL 147.A N GLY 64.A O no hydrogen 2.941 N/A ILE 148.A N ASN 133.A O no hydrogen 2.972 N/A ASP 149.A N TYR 56.A OH no hydrogen 3.152 N/A PHE 150.A N GLU 52.A OE1 no hydrogen 3.224 N/A SER 153.A N PHE 150.A O no hydrogen 3.258 N/A SER 153.A OG PHE 150.A O no hydrogen 2.508 N/A TYR 154.A OH HIS 120.A O no hydrogen 2.565 N/A ARG 155.A NE SER 123.A OG no hydrogen 2.645 N/A ASP 156.A N ARG 161.A O no hydrogen 3.333 N/A PHE 157.A N ASP 156.A OD1 no hydrogen 2.414 N/A HIS 162.A ND1 ILE 163.A O no hydrogen 3.061 N/A ILE 163.A N TYR 154.A O no hydrogen 2.894 N/A LYS 169.A N GLY 183.A O no hydrogen 2.699 N/A ARG 174.A NH1 TYR 175.A OH no hydrogen 3.559 N/A ALA 176.A N THR 172.A O no hydrogen 3.184 N/A SER 177.A OG ASP 190.A OD1 no hydrogen 2.660 N/A SER 177.A OG GLU 193.A OE1 no hydrogen 3.013 N/A VAL 178.A N GLU 193.A OE2 no hydrogen 3.168 N/A ASN 179.A ND2 ASP 190.A OD1 no hydrogen 3.552 N/A THR 180.A N SER 177.A O no hydrogen 3.037 N/A HIS 181.A N SER 177.A O no hydrogen 3.388 N/A HIS 181.A N VAL 178.A O no hydrogen 3.160 N/A LEU 182.A N VAL 178.A O no hydrogen 3.302 N/A GLY 183.A N THR 180.A O no hydrogen 3.356 N/A ILE 184.A N ASN 179.A O no hydrogen 2.912 N/A GLU 185.A N ARG 166.A O no hydrogen 3.253 N/A SER 187.A N ASP 190.A OD2 no hydrogen 2.567 N/A SER 187.A OG PHE 254.A O no hydrogen 2.571 N/A ARG 188.A NH2 ASP 255.A O no hydrogen 2.954 N/A ARG 189.A NH1 LEU 252.A O no hydrogen 3.169 N/A ASP 190.A N SER 187.A O no hydrogen 3.193 N/A LEU 192.A N ARG 188.A O no hydrogen 3.412 N/A GLU 193.A N ARG 189.A O no hydrogen 3.010 N/A SER 194.A N ASP 190.A O no hydrogen 3.085 N/A SER 194.A OG TYR 175.A O no hydrogen 2.968 N/A SER 194.A OG ASP 190.A O no hydrogen 2.755 N/A LEU 195.A N ASP 191.A O no hydrogen 2.922 N/A GLY 196.A N LEU 192.A O no hydrogen 3.045 N/A TYR 197.A N GLU 193.A O no hydrogen 3.182 N/A TYR 197.A OH GLU 193.A OE2 no hydrogen 2.951 N/A VAL 198.A N SER 194.A O no hydrogen 3.227 N/A LEU 199.A N LEU 195.A O no hydrogen 3.057 N/A ILE 200.A N GLY 196.A O no hydrogen 2.982 N/A TYR 201.A N TYR 197.A O no hydrogen 3.034 N/A TYR 201.A OH GLU 90.A OE1 no hydrogen 3.175 N/A TYR 201.A OH GLU 90.A OE2 no hydrogen 3.235 N/A PHE 202.A N VAL 198.A O no hydrogen 2.890 N/A PHE 202.A N LEU 199.A O no hydrogen 3.074 N/A CYS 203.A N LEU 199.A O no hydrogen 3.142 N/A CYS 203.A SG LEU 199.A O no hydrogen 3.465 N/A LYS 204.A N ILE 200.A O no hydrogen 3.046 N/A LYS 204.A NZ LEU 235.A O no hydrogen 3.552 N/A LYS 204.A NZ SER 237.A OG no hydrogen 2.762 N/A GLY 205.A N TYR 201.A O no hydrogen 2.887 N/A TRP 209.A NE1 ARG 174.A O no hydrogen 2.852 N/A GLN 210.A N LEU 207.A O no hydrogen 3.004 N/A LYS 220.A N THR 216.A O no hydrogen 3.302 N/A TYR 221.A N LYS 217.A O no hydrogen 3.446 N/A ASP 222.A N LYS 218.A O no hydrogen 3.002 N/A ARG 223.A N GLN 219.A O no hydrogen 2.859 N/A ARG 223.A NH1 LYS 213.A O no hydrogen 2.712 N/A MET 225.A N TYR 221.A O no hydrogen 3.454 N/A GLU 226.A N ASP 222.A O no hydrogen 2.880 N/A LYS 227.A NZ ALA 173.A O no hydrogen 3.122 N/A LYS 227.A NZ ALA 176.A O no hydrogen 2.323 N/A LYS 227.A NZ HIS 181.A NE2 no hydrogen 3.198 N/A LEU 228.A N MET 225.A O no hydrogen 3.398 N/A GLU 233.A N GLU 233.A OE1 no hydrogen 2.506 N/A THR 234.A OG1 SER 231.A OG no hydrogen 2.762 N/A LEU 235.A N SER 231.A O no hydrogen 2.970 N/A CYS 236.A N VAL 232.A O no hydrogen 3.049 N/A CYS 236.A SG VAL 232.A O no hydrogen 3.566 N/A GLU 242.A N GLU 242.A OE1 no hydrogen 2.733 N/A PHE 243.A N PRO 240.A O no hydrogen 3.136 N/A GLU 245.A N LEU 241.A O no hydrogen 2.829 N/A TYR 246.A N GLU 242.A O no hydrogen 3.038 N/A TYR 246.A OH LEU 192.A O no hydrogen 2.861 N/A MET 247.A N PHE 243.A O no hydrogen 3.098 N/A ALA 248.A N GLN 244.A O no hydrogen 2.920 N/A TYR 249.A N GLU 245.A O no hydrogen 3.160 N/A CYS 250.A N TYR 246.A O no hydrogen 3.021 N/A CYS 250.A SG TYR 246.A O no hydrogen 3.283 N/A LEU 252.A N CYS 250.A O no hydrogen 3.459 N/A LYS 253.A N GLU 256.A OE2 no hydrogen 2.607 N/A ASP 258.A N TYR 249.A OH no hydrogen 2.707 N/A TYR 259.A OH HIS 120.A ND1 no hydrogen 2.921 N/A PHE 261.A N ASP 258.A O no hydrogen 3.011 N/A LEU 262.A N ASP 258.A O no hydrogen 3.250 N/A ALA 263.A N TYR 259.A O no hydrogen 3.023 N/A ARG 264.A N LEU 260.A O no hydrogen 2.977 N/A LEU 265.A N PHE 261.A O no hydrogen 2.871 N/A LYS 267.A N ALA 263.A O no hydrogen 3.015 N/A ASP 268.A N ARG 264.A O no hydrogen 2.657 N/A SER 270.A N PHE 266.A O no hydrogen 2.992 N/A SER 270.A OG PHE 266.A O no hydrogen 3.488 N/A SER 270.A OG LYS 267.A O no hydrogen 2.620 N/A ILE 271.A N LYS 267.A O no hydrogen 3.304 N/A LYS 272.A N ASP 268.A O no hydrogen 3.078 N/A LEU 273.A N LEU 269.A O no hydrogen 2.897 N/A GLU 274.A N ILE 271.A O no hydrogen 3.069 N/A TYR 275.A N SER 270.A O no hydrogen 2.717 N/A TYR 275.A OH HIS 327.A ND1 no hydrogen 2.527 N/A ASP 278.A N HIS 276.A O no hydrogen 2.936 N/A ASP 282.A N THR 104.A OG1 no hydrogen 3.158 N/A MET 285.A N PHE 281.A O no hydrogen 3.254 N/A LEU 286.A N ASP 282.A O no hydrogen 2.884 N/A ARG 287.A N TRP 283.A O no hydrogen 2.906 N/A TYR 288.A N THR 284.A O no hydrogen 3.228 N/A THR 289.A N MET 285.A O no hydrogen 2.924 N/A THR 289.A OG1 MET 285.A O no hydrogen 2.927 N/A LYS 290.A N LEU 286.A O no hydrogen 2.827 N/A ALA 291.A N ARG 287.A O no hydrogen 3.097 N/A MET 292.A N TYR 288.A O no hydrogen 2.824 N/A VAL 293.A N THR 289.A O no hydrogen 2.987 N/A GLU 294.A N LYS 290.A O no hydrogen 3.052 N/A LYS 295.A N ALA 291.A O no hydrogen 3.298 N/A GLN 296.A N VAL 293.A O no hydrogen 3.135 N/A GLN 296.A NE2 GLU 357.A O no hydrogen 3.511 N/A ARG 297.A N GLU 294.A O no hydrogen 3.195 N/A LEU 300.A N GLN 296.A O no hydrogen 3.176 N/A ILE 301.A N ARG 297.A O no hydrogen 2.974 N/A GLU 302.A N ASP 298.A O no hydrogen 3.181 N/A LYS 303.A N LEU 299.A O no hydrogen 3.511 N/A LYS 308.A N THR 305.A O no hydrogen 3.309 N/A GLU 310.A N ASN 307.A O no hydrogen 2.840 N/A THR 311.A N ASN 307.A O no hydrogen 2.483 N/A THR 311.A OG1 ASN 307.A O no hydrogen 2.866 N/A THR 311.A OG1 LYS 308.A O no hydrogen 3.387 N/A PHE 312.A N LYS 308.A O no hydrogen 3.002 N/A LYS 314.A N GLU 310.A O no hydrogen 3.161 N/A ILE 315.A N THR 311.A O no hydrogen 2.869 N/A LEU 317.A N LYS 314.A O no hydrogen 3.241 N/A ALA 318.A N ILE 315.A O no hydrogen 3.080 N/A LYS 320.A N LEU 316.A O no hydrogen 2.983 N/A LYS 320.A N LEU 317.A O no hydrogen 3.204 N/A LYS 321.A N LEU 317.A O no hydrogen 3.040 N/A PHE 322.A N ALA 318.A O no hydrogen 2.970 N/A THR 324.A OG1 HIS 325.A ND1 no hydrogen 3.037 N/A HIS 325.A N PHE 322.A O no hydrogen 3.228 N/A HIS 325.A ND1 THR 324.A OG1 no hydrogen 3.037 N/A HIS 325.A NE2 ASP 278.A OD2 no hydrogen 2.728 N/A HIS 327.A ND1 TYR 275.A OH no hydrogen 2.527 N/A HIS 327.A NE2 THR 344.A OG1 no hydrogen 2.597 N/A TYR 328.A N GLN 343.A OE1 no hydrogen 3.139 N/A LYS 333.A NZ GLU 331.A O no hydrogen 3.551 N/A SER 337.A OG GLU 339.A OE1 no hydrogen 2.791 N/A GLU 339.A N GLU 339.A OE1 no hydrogen 2.590 N/A ILE 341.A N SER 337.A O no hydrogen 3.257 N/A GLN 343.A NE2 TYR 328.A O no hydrogen 2.922 N/A THR 344.A OG1 PRO 323.A O no hydrogen 3.242 N/A THR 344.A OG1 HIS 327.A NE2 no hydrogen 2.597 N/A LEU 346.A N GLN 342.A O no hydrogen 3.445 N/A ASN 347.A N GLN 343.A O no hydrogen 2.792 N/A ASN 347.A ND2 PHE 326.A O no hydrogen 2.931 N/A ASN 348.A N THR 344.A O no hydrogen 2.815 N/A ASN 349.A N ILE 345.A O no hydrogen 2.925 N/A LEU 359.A N PRO 355.A O no hydrogen 3.073 N/A ALA 361.A N GLU 357.A O no hydrogen 3.355 N/A LEU 362.A N LEU 358.A O no hydrogen 2.843 N/A ASP 363.A N LEU 359.A O no hydrogen 3.068 N/A