Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5e1s_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 9.A N VAL 83.A O no hydrogen 2.768 N/A ARG 11.A NE LYS 86.A O no hydrogen 3.456 N/A ARG 11.A NH1 PRO 89.A O no hydrogen 2.702 N/A ARG 11.A NH2 LYS 86.A O no hydrogen 2.788 N/A ARG 11.A NH2 PRO 89.A O no hydrogen 2.801 N/A LYS 13.A N SER 10.A O no hydrogen 3.159 N/A LYS 13.A NZ ASP 35.A O no hydrogen 3.493 N/A ILE 14.A N ARG 11.A O no hydrogen 3.421 N/A THR 15.A N ASN 32.A O no hydrogen 3.044 N/A LEU 17.A N GLU 30.A O no hydrogen 2.784 N/A ARG 18.A N GLU 30.A O no hydrogen 3.288 N/A ARG 18.A NE GLU 30.A OE1 no hydrogen 2.834 N/A ARG 18.A NH2 GLU 30.A OE1 no hydrogen 3.035 N/A LEU 20.A N VAL 28.A O no hydrogen 2.794 N/A GLY 21.A N VAL 28.A O no hydrogen 3.378 N/A GLY 23.A N GLY 26.A O no hydrogen 2.861 N/A VAL 28.A N GLY 21.A O no hydrogen 2.964 N/A TYR 29.A N VAL 47.A O no hydrogen 2.801 N/A GLU 30.A N ARG 18.A O no hydrogen 2.734 N/A GLY 31.A N VAL 45.A O no hydrogen 2.788 N/A ASN 32.A N THR 15.A O no hydrogen 2.953 N/A ALA 33.A N THR 43.A O no hydrogen 2.819 N/A ARG 34.A N LYS 13.A O no hydrogen 2.892 N/A ASP 35.A N ALA 41.A O no hydrogen 3.124 N/A GLU 40.A N ILE 37.A O no hydrogen 3.090 N/A THR 43.A N ALA 33.A O no hydrogen 3.000 N/A THR 43.A OG1 GLU 40.A OE1 no hydrogen 2.630 N/A ARG 44.A NH2 GLU 30.A OE2 no hydrogen 3.493 N/A VAL 45.A N GLY 31.A O no hydrogen 2.872 N/A ALA 46.A N MET 94.A O no hydrogen 3.048 N/A VAL 47.A N TYR 29.A O no hydrogen 2.709 N/A LYS 48.A N VAL 92.A O no hydrogen 2.738 N/A LYS 48.A NZ ASP 168.A OD1 no hydrogen 2.759 N/A THR 49.A N MET 27.A O no hydrogen 3.199 N/A THR 49.A OG1 MET 27.A O no hydrogen 2.549 N/A ASN 51.A N PHE 25.A O no hydrogen 3.079 N/A ASN 51.A ND2 SER 53.A OG no hydrogen 2.573 N/A ALA 54.A N ASN 51.A O no hydrogen 3.292 N/A SER 55.A N GLU 58.A OE1 no hydrogen 2.806 N/A SER 55.A OG GLU 58.A OE1 no hydrogen 2.919 N/A ARG 57.A NH1 GLU 61.A OE1 no hydrogen 3.087 N/A ARG 57.A NH1 GLU 61.A OE2 no hydrogen 3.404 N/A GLU 58.A N SER 55.A OG no hydrogen 3.259 N/A ARG 59.A N SER 55.A O no hydrogen 2.960 N/A ARG 59.A NH2 GLU 52.A O no hydrogen 3.142 N/A ILE 60.A N LEU 56.A O no hydrogen 2.895 N/A GLU 61.A N ARG 57.A O no hydrogen 2.982 N/A PHE 62.A N GLU 58.A O no hydrogen 3.206 N/A LEU 63.A N ARG 59.A O no hydrogen 3.340 N/A ASN 64.A N ILE 60.A O no hydrogen 2.983 N/A GLU 65.A N GLU 61.A O no hydrogen 3.092 N/A ALA 66.A N PHE 62.A O no hydrogen 3.412 N/A SER 67.A N LEU 63.A O no hydrogen 3.110 N/A VAL 68.A N ASN 64.A O no hydrogen 3.251 N/A MET 69.A N GLU 65.A O no hydrogen 3.061 N/A LYS 70.A N SER 67.A O no hydrogen 3.331 N/A LYS 70.A NZ TYR 2.A OH no hydrogen 2.965 N/A LYS 70.A NZ ASP 5.A OD1 no hydrogen 3.057 N/A LYS 70.A NZ ASP 5.A OD2 no hydrogen 3.089 N/A LYS 70.A NZ SER 67.A OG no hydrogen 3.215 N/A GLY 71.A N VAL 68.A O no hydrogen 3.390 N/A PHE 72.A N MET 69.A O no hydrogen 3.031 N/A THR 73.A N TYR 140.A OH no hydrogen 2.850 N/A HIS 76.A ND1 ASP 136.A OD2 no hydrogen 2.771 N/A VAL 77.A N CYS 74.A O no hydrogen 3.359 N/A VAL 78.A N ILE 166.A O no hydrogen 2.866 N/A ARG 79.A N GLU 95.A OE2 no hydrogen 2.794 N/A LEU 81.A N VAL 93.A O no hydrogen 2.738 N/A GLY 82.A N VAL 93.A O no hydrogen 3.273 N/A VAL 84.A N LEU 91.A O no hydrogen 2.919 N/A SER 85.A N GLU 8.A OE2 no hydrogen 2.792 N/A SER 85.A OG GLU 8.A OE1 no hydrogen 2.647 N/A SER 85.A OG GLU 8.A OE2 no hydrogen 3.214 N/A LYS 86.A N GLU 8.A OE2 no hydrogen 3.502 N/A LEU 91.A N VAL 84.A O no hydrogen 3.003 N/A VAL 92.A N LYS 48.A O no hydrogen 2.930 N/A VAL 93.A N GLY 82.A O no hydrogen 2.857 N/A MET 94.A N ALA 46.A O no hydrogen 2.816 N/A GLU 95.A N ARG 79.A O no hydrogen 2.947 N/A HIS 99.A N.A VAL 158.A O no hydrogen 3.007 N/A HIS 99.A N.B VAL 158.A O no hydrogen 3.009 N/A HIS 99.A ND1.A ALA 159.A O no hydrogen 2.735 N/A GLY 100.A N MET 97.A O no hydrogen 2.940 N/A LEU 102.A N CYS 156.A O no hydrogen 2.710 N/A LYS 103.A N ALA 153.A O no hydrogen 3.203 N/A SER 104.A N ASP 101.A OD2 no hydrogen 2.884 N/A SER 104.A OG ASP 101.A OD1 no hydrogen 2.782 N/A SER 104.A OG ASP 101.A OD2 no hydrogen 3.046 N/A TYR 105.A N ASP 101.A O no hydrogen 3.182 N/A LEU 106.A N LEU 102.A O no hydrogen 2.889 N/A ARG 107.A N LYS 103.A O no hydrogen 3.066 N/A ARG 107.A NH2 ALA 207.A O no hydrogen 3.455 N/A SER 108.A N SER 104.A O no hydrogen 3.207 N/A SER 108.A OG TYR 105.A O no hydrogen 2.681 N/A LEU 109.A N LEU 106.A O no hydrogen 3.253 N/A ARG 110.A N ARG 107.A O no hydrogen 3.375 N/A ARG 110.A NE GLU 112.A OE1 no hydrogen 3.034 N/A ARG 110.A NH1 SER 205.A O no hydrogen 3.137 N/A ARG 110.A NH1 LEU 206.A O no hydrogen 2.788 N/A ALA 113.A N ARG 110.A O no hydrogen 3.381 N/A ASN 116.A ND2 ARG 110.A O no hydrogen 2.932 N/A GLY 118.A N ASN 116.A OD1 no hydrogen 3.084 N/A THR 123.A N GLU 126.A OE1 no hydrogen 2.991 N/A GLU 126.A N THR 123.A OG1 no hydrogen 3.070 N/A MET 127.A N THR 123.A O no hydrogen 2.881 N/A ILE 128.A N LEU 124.A O no hydrogen 2.931 N/A GLN 129.A N GLN 125.A O no hydrogen 2.928 N/A GLN 129.A NE2 GLU 133.A OE2 no hydrogen 2.734 N/A MET 130.A N GLU 126.A O no hydrogen 2.940 N/A ALA 131.A N MET 127.A O no hydrogen 2.949 N/A ALA 132.A N ILE 128.A O no hydrogen 3.031 N/A GLU 133.A N GLN 129.A O no hydrogen 3.034 N/A ILE 134.A N MET 130.A O no hydrogen 2.910 N/A ALA 135.A N ALA 131.A O no hydrogen 2.997 N/A ASP 136.A N ALA 132.A O no hydrogen 2.806 N/A GLY 137.A N GLU 133.A O no hydrogen 3.160 N/A MET 138.A N ILE 134.A O no hydrogen 2.958 N/A ALA 139.A N ALA 135.A O no hydrogen 2.779 N/A TYR 140.A N ASP 136.A O no hydrogen 2.958 N/A TYR 140.A OH GLY 71.A O no hydrogen 3.354 N/A LEU 141.A N GLY 137.A O no hydrogen 3.002 N/A ASN 142.A N MET 138.A O no hydrogen 2.989 N/A ALA 143.A N ALA 139.A O no hydrogen 2.999 N/A LYS 144.A N TYR 140.A O no hydrogen 2.953 N/A LYS 144.A NZ GLY 71.A O no hydrogen 3.515 N/A LYS 145.A N ASN 142.A O no hydrogen 2.978 N/A PHE 146.A N LEU 141.A O no hydrogen 2.951 N/A HIS 148.A N ASP 192.A OD2 no hydrogen 2.948 N/A ARG 149.A N ASP 192.A OD1 no hydrogen 3.027 N/A ASN 150.A N HIS 148.A ND1 no hydrogen 3.151 N/A ASN 150.A ND2 ASN 150.A O no hydrogen 3.373 N/A ALA 153.A N GLU 202.A OE1 no hydrogen 2.993 N/A ASN 155.A N ALA 152.A O no hydrogen 3.054 N/A CYS 156.A N ALA 153.A O no hydrogen 3.144 N/A CYS 156.A SG ALA 152.A O no hydrogen 3.539 N/A MET 157.A N LYS 165.A O no hydrogen 2.855 N/A VAL 158.A N GLY 100.A O no hydrogen 2.725 N/A ALA 159.A N THR 163.A O no hydrogen 2.869 N/A PHE 162.A N ALA 159.A O no hydrogen 3.135 N/A THR 163.A N ASP 161.A OD1 no hydrogen 3.456 N/A THR 163.A OG1 ASP 161.A OD1 no hydrogen 2.928 N/A THR 163.A OG1 ASP 161.A OD2 no hydrogen 3.479 N/A VAL 164.A N GLU 133.A OE1 no hydrogen 3.026 N/A LYS 165.A N MET 157.A O no hydrogen 2.964 N/A LYS 165.A NZ HIS 75.A O no hydrogen 3.208 N/A LYS 165.A NZ GLU 95.A OE1 no hydrogen 2.787 N/A ILE 166.A N HIS 76.A O no hydrogen 2.991 N/A GLY 167.A N ASN 155.A O no hydrogen 3.049 N/A GLY 170.A N HIS 148.A O no hydrogen 3.135 N/A VAL 174.A N LEU 172.A O no hydrogen 2.795 N/A ARG 175.A NE ASN 216.A OD1 no hydrogen 3.147 N/A ARG 175.A NH1 PRO 210.A O no hydrogen 2.868 N/A ARG 175.A NH1 TYR 211.A O no hydrogen 2.933 N/A ARG 175.A NH1 LEU 214.A O no hydrogen 3.216 N/A ARG 175.A NH2 LEU 214.A O no hydrogen 2.793 N/A ARG 175.A NH2 ASN 216.A OD1 no hydrogen 3.035 N/A TRP 176.A N PRO 173.A O no hydrogen 3.156 N/A TRP 176.A NE1 GLU 202.A OE1 no hydrogen 2.780 N/A MET 177.A N VAL 174.A O no hydrogen 3.385 N/A GLU 180.A N GLU 180.A OE1 no hydrogen 2.849 N/A SER 181.A N ALA 178.A O no hydrogen 2.964 N/A SER 181.A OG VAL 186.A O no hydrogen 2.598 N/A LEU 182.A N ALA 178.A O no hydrogen 3.068 N/A LYS 183.A N PRO 179.A O no hydrogen 3.034 N/A ASP 184.A N GLU 180.A O no hydrogen 2.852 N/A GLY 185.A N SER 181.A O no hydrogen 3.045 N/A THR 188.A N SER 191.A OG no hydrogen 2.790 N/A SER 190.A N THR 188.A OG1 no hydrogen 3.260 N/A SER 191.A N THR 188.A O no hydrogen 3.147 N/A SER 191.A N THR 188.A OG1 no hydrogen 3.335 N/A SER 191.A OG THR 188.A O no hydrogen 2.732 N/A ASP 192.A N THR 188.A O no hydrogen 3.090 N/A MET 193.A N THR 189.A O no hydrogen 2.970 N/A TRP 194.A N SER 190.A O no hydrogen 3.318 N/A SER 195.A N SER 191.A O no hydrogen 3.239 N/A SER 195.A OG TRP 176.A O no hydrogen 2.675 N/A SER 195.A OG SER 191.A O no hydrogen 3.522 N/A PHE 196.A N ASP 192.A O no hydrogen 2.940 N/A GLY 197.A N MET 193.A O no hydrogen 3.097 N/A VAL 198.A N TRP 194.A O no hydrogen 3.227 N/A VAL 199.A N SER 195.A O no hydrogen 2.913 N/A LEU 200.A N PHE 196.A O no hydrogen 2.941 N/A TRP 201.A N GLY 197.A O no hydrogen 3.025 N/A TRP 201.A NE1 ASP 230.A O no hydrogen 2.709 N/A GLU 202.A N VAL 198.A O no hydrogen 2.866 N/A ILE 203.A N VAL 199.A O no hydrogen 2.962 N/A THR 204.A N LEU 200.A O no hydrogen 3.121 N/A THR 204.A OG1 LEU 200.A O no hydrogen 3.220 N/A THR 204.A OG1 TRP 201.A O no hydrogen 3.181 N/A SER 205.A N TRP 201.A O no hydrogen 2.977 N/A SER 205.A OG TRP 201.A O no hydrogen 2.928 N/A SER 205.A OG GLU 202.A O no hydrogen 3.569 N/A LEU 206.A N ILE 203.A O no hydrogen 3.365 N/A ALA 207.A N GLU 202.A O no hydrogen 2.679 N/A GLU 208.A N SER 205.A OG no hydrogen 3.298 N/A LEU 214.A N TYR 211.A O no hydrogen 3.105 N/A SER 215.A N GLN 218.A OE1 no hydrogen 2.925 N/A SER 215.A OG GLN 218.A OE1 no hydrogen 3.043 N/A GLN 218.A N SER 215.A OG no hydrogen 3.331 N/A VAL 219.A N SER 215.A O no hydrogen 2.897 N/A LEU 220.A N ASN 216.A O no hydrogen 3.350 N/A LYS 221.A N GLU 217.A O no hydrogen 3.275 N/A LYS 221.A NZ ASP 225.A OD2 no hydrogen 3.059 N/A PHE 222.A N GLN 218.A O no hydrogen 2.960 N/A VAL 223.A N VAL 219.A O no hydrogen 2.892 N/A MET 224.A N LEU 220.A O no hydrogen 3.258 N/A ASP 225.A N LYS 221.A O no hydrogen 3.072 N/A GLY 226.A N VAL 223.A O no hydrogen 3.067 N/A GLY 227.A N PHE 222.A O no hydrogen 2.858 N/A CYS 235.A N PRO 232.A O no hydrogen 3.249 N/A CYS 235.A SG PRO 236.A O no hydrogen 3.583 N/A CYS 235.A SG THR 240.A OG1 no hydrogen 3.133 N/A ARG 238.A NH2 LEU 263.A O no hydrogen 3.459 N/A VAL 239.A N PRO 236.A O no hydrogen 3.097 N/A THR 240.A N PRO 236.A O no hydrogen 3.200 N/A THR 240.A OG1 PRO 236.A O no hydrogen 3.391 N/A ASP 241.A N GLU 237.A O no hydrogen 2.938 N/A LEU 242.A N ARG 238.A O no hydrogen 3.364 N/A MET 243.A N VAL 239.A O no hydrogen 3.053 N/A ARG 244.A N THR 240.A O no hydrogen 3.057 N/A MET 245.A N ASP 241.A O no hydrogen 3.314 N/A CYS 246.A N LEU 242.A O no hydrogen 3.183 N/A CYS 246.A SG MET 193.A O no hydrogen 3.495 N/A CYS 246.A SG LEU 242.A O no hydrogen 3.322 N/A TRP 247.A N MET 243.A O no hydrogen 2.992 N/A TRP 247.A N ARG 244.A O no hydrogen 3.267 N/A TRP 247.A NE1 TRP 194.A O no hydrogen 3.229 N/A GLN 248.A NE2 ARG 244.A O no hydrogen 2.833 N/A LYS 252.A N ASN 250.A OD1 no hydrogen 3.296 N/A MET 253.A N ASN 250.A O no hydrogen 3.002 N/A ARG 254.A N PRO 251.A O no hydrogen 3.341 N/A ARG 254.A NE GLN 248.A O no hydrogen 2.765 N/A ARG 254.A NH1 GLU 180.A OE2 no hydrogen 2.691 N/A ARG 254.A NH1 SER 190.A O no hydrogen 2.902 N/A ARG 254.A NH2 GLU 180.A OE1 no hydrogen 2.818 N/A ARG 254.A NH2 GLN 248.A O no hydrogen 3.136 N/A THR 256.A N GLU 259.A OE1 no hydrogen 3.001 N/A GLU 259.A N THR 256.A OG1 no hydrogen 3.266 N/A ILE 260.A N THR 256.A O no hydrogen 3.145 N/A VAL 261.A N PHE 257.A O no hydrogen 3.233 N/A ASN 262.A N LEU 258.A O no hydrogen 2.949 N/A LEU 263.A N GLU 259.A O no hydrogen 3.035 N/A LEU 263.A N ILE 260.A O no hydrogen 3.098 N/A LEU 264.A N ILE 260.A O no hydrogen 3.228 N/A LEU 264.A N VAL 261.A O no hydrogen 3.162 N/A LYS 265.A N VAL 261.A O no hydrogen 2.772 N/A LYS 265.A NZ ASN 262.A O no hydrogen 3.432 N/A LYS 265.A NZ ASN 262.A OD1 no hydrogen 2.829 N/A ASP 267.A N LEU 264.A O no hydrogen 3.114 N/A HIS 269.A N GLN 129.A OE1 no hydrogen 2.908 N/A HIS 269.A ND1 SER 271.A OG no hydrogen 2.841 N/A SER 271.A N HIS 269.A ND1 no hydrogen 3.109 N/A SER 271.A OG HIS 269.A ND1 no hydrogen 2.841 N/A PHE 272.A N HIS 269.A O no hydrogen 3.074 N/A GLU 274.A N SER 271.A O no hydrogen 2.907 N/A VAL 275.A N PHE 272.A O no hydrogen 3.213 N/A SER 276.A N PHE 272.A O no hydrogen 2.886 N/A SER 276.A OG PHE 272.A O no hydrogen 3.141 N/A SER 276.A OG HIS 279.A ND1 no hydrogen 2.789 N/A PHE 277.A N ASP 136.A OD2 no hydrogen 2.820 N/A PHE 278.A N ASP 136.A OD1 no hydrogen 2.796 N/A HIS 279.A N SER 276.A OG no hydrogen 3.114 N/A HIS 279.A ND1 SER 276.A OG no hydrogen 2.789 N/A SER 280.A N PHE 277.A O no hydrogen 2.995 N/A SER 280.A OG PHE 277.A O no hydrogen 2.722 N/A GLU 282.A N SER 280.A OG no hydrogen 3.172 N/A ASN 283.A N SER 280.A O no hydrogen 3.350 N/A ASN 283.A ND2 PHE 278.A O no hydrogen 2.858 N/A