Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5e43_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ARG 5.A N.A GLY 1.A O no hydrogen 2.922 N/A ARG 5.A N.B GLY 1.A O no hydrogen 2.905 N/A ARG 5.A NH1.A THR 33.A O no hydrogen 2.910 N/A LYS 6.A N ALA 2.A O no hydrogen 3.132 N/A GLU 7.A N ARG 3.A O no hydrogen 2.976 N/A LEU 8.A N ALA 4.A O no hydrogen 2.876 N/A ARG 9.A N ARG 5.A O.A no hydrogen 2.855 N/A ARG 9.A N ARG 5.A O.B no hydrogen 2.868 N/A THR 10.A N LYS 6.A O no hydrogen 3.004 N/A THR 10.A OG1 LYS 6.A O no hydrogen 3.086 N/A LEU 11.A N GLU 7.A O no hydrogen 2.896 N/A GLU 12.A N LEU 8.A O no hydrogen 2.789 N/A ALA 13.A N ARG 9.A O no hydrogen 2.997 N/A SER 14.A N THR 10.A O no hydrogen 3.002 N/A SER 14.A OG LEU 11.A O no hydrogen 2.646 N/A PHE 15.A N GLU 12.A O no hydrogen 3.350 N/A LYS 16.A N ALA 13.A O no hydrogen 3.263 N/A GLY 17.A N GLU 12.A O no hydrogen 3.452 N/A ARG 18.A N ASN 237.A O no hydrogen 2.834 N/A ARG 18.A NE ASN 237.A OD1 no hydrogen 2.846 N/A ARG 18.A NH1 GLU 38.A OE1 no hydrogen 2.968 N/A ARG 18.A NH1 ARG 39.A O no hydrogen 3.117 N/A ARG 18.A NH2 ARG 39.A O no hydrogen 2.864 N/A ARG 18.A NH2 ASN 237.A OD1 no hydrogen 2.954 N/A ILE 19.A N GLU 12.A OE2 no hydrogen 2.852 N/A GLY 20.A N TYR 235.A O no hydrogen 2.726 N/A ALA 21.A N TYR 34.A O no hydrogen 2.782 N/A TYR 22.A N SER 233.A O no hydrogen 2.967 N/A ALA 23.A N ILE 32.A O no hydrogen 2.901 N/A VAL 24.A N ILE 232.A O.A no hydrogen 3.020 N/A VAL 24.A N ILE 232.A O.B no hydrogen 3.003 N/A ASP 25.A N LYS 30.A O no hydrogen 2.989 N/A THR 26.A N PRO 230.A O no hydrogen 3.129 N/A THR 26.A OG1 PRO 230.A O no hydrogen 2.624 N/A ALA 27.A N ASP 25.A OD1 no hydrogen 2.760 N/A THR 28.A N ASP 25.A OD1 no hydrogen 3.312 N/A GLY 29.A N ASP 25.A O no hydrogen 2.859 N/A LYS 30.A N THR 28.A OG1 no hydrogen 2.961 N/A LYS 30.A NZ ALA 260.A O no hydrogen 3.248 N/A ILE 32.A N ALA 23.A O no hydrogen 2.866 N/A TYR 34.A N ALA 21.A O no hydrogen 2.910 N/A TYR 34.A OH GLU 12.A OE1 no hydrogen 2.727 N/A ARG 35.A NE GLU 12.A OE1 no hydrogen 3.513 N/A ARG 35.A NE GLU 12.A OE2 no hydrogen 2.767 N/A ARG 35.A NH1 GLU 38.A OE2 no hydrogen 2.888 N/A ARG 35.A NH2 GLU 12.A OE1 no hydrogen 3.047 N/A GLU 38.A N ARG 35.A O no hydrogen 3.072 N/A ARG 39.A NH1 PRO 147.A O no hydrogen 3.111 N/A ARG 39.A NH1 GLU 149.A O no hydrogen 2.903 N/A PHE 40.A N THR 154.A O no hydrogen 3.089 N/A LEU 42.A N ASP 152.A O no hydrogen 2.901 N/A SER 44.A OG SER 104.A OG no hydrogen 3.073 N/A THR 45.A N LEU 42.A O no hydrogen 3.032 N/A THR 45.A OG1 LEU 42.A O no hydrogen 2.693 N/A THR 45.A OG1 TYR 235.A OH no hydrogen 2.795 N/A PHE 46.A N LEU 43.A O no hydrogen 3.465 N/A LYS 47.A N SER 44.A O no hydrogen 3.054 N/A LYS 47.A NZ SER 44.A OG no hydrogen 2.840 N/A LYS 47.A NZ SER 104.A O no hydrogen 2.895 N/A LYS 47.A NZ SER 104.A OG no hydrogen 3.037 N/A LYS 47.A NZ ASN 106.A OD1 no hydrogen 2.766 N/A ALA 48.A N THR 45.A O no hydrogen 3.369 N/A ALA 50.A N PHE 46.A O no hydrogen 2.860 N/A ALA 51.A N LYS 47.A O no hydrogen 3.066 N/A ALA 52.A N ALA 48.A O no hydrogen 3.223 N/A ALA 53.A N ILE 49.A O no hydrogen 2.834 N/A VAL 54.A N ALA 50.A O no hydrogen 2.983 N/A LEU 55.A N ALA 51.A O no hydrogen 2.864 N/A HIS 56.A N ALA 52.A O no hydrogen 2.829 N/A LYS 57.A N ALA 53.A O no hydrogen 2.936 N/A LYS 57.A NZ GLN 114.A O no hydrogen 2.722 N/A ALA 58.A N VAL 54.A O no hydrogen 2.927 N/A ARG 59.A N LEU 55.A O no hydrogen 3.019 N/A ARG 59.A NE ASP 175.A OD2 no hydrogen 2.887 N/A ARG 59.A NH2 ASP 175.A OD1 no hydrogen 2.947 N/A THR 60.A N HIS 56.A O no hydrogen 3.018 N/A THR 60.A OG1 HIS 56.A O no hydrogen 2.811 N/A SER 61.A N LYS 57.A O no hydrogen 2.942 N/A SER 61.A OG LYS 57.A O no hydrogen 3.481 N/A ASP 62.A N LYS 57.A O no hydrogen 2.917 N/A LEU 65.A N ASP 62.A O no hydrogen 3.078 N/A ASN 67.A N GLY 64.A O no hydrogen 3.038 N/A LYS 68.A N LEU 65.A O no hydrogen 3.077 N/A LYS 68.A NZ GLN 114.A OE1 no hydrogen 2.694 N/A TRP 72.A NE1 THR 84.A O no hydrogen 3.025 N/A THR 73.A N GLU 76.A OE1 no hydrogen 2.990 N/A GLU 76.A N THR 73.A O no hydrogen 3.224 N/A GLU 76.A N THR 73.A OG1 no hydrogen 3.132 N/A LEU 77.A N THR 74.A O.A no hydrogen 3.196 N/A LEU 77.A N THR 74.A O.B no hydrogen 3.019 N/A GLN 78.A N THR 107.A OG1 no hydrogen 2.870 N/A HIS 80.A NE2 ARG 103.A O no hydrogen 2.788 N/A SER 81.A OG GLN 78.A O no hydrogen 2.610 N/A SER 81.A OG THR 107.A OG1 no hydrogen 2.566 N/A VAL 83.A N ASP 105.A OD2 no hydrogen 2.883 N/A THR 84.A N ASP 105.A OD2 no hydrogen 2.867 N/A THR 84.A OG1 ASP 105.A OD1 no hydrogen 2.741 N/A THR 84.A OG1 ASP 105.A OD2 no hydrogen 3.143 N/A GLY 85.A N SER 81.A O no hydrogen 2.846 N/A LYS 86.A N VAL 83.A O no hydrogen 2.957 N/A HIS 87.A N THR 84.A O no hydrogen 3.074 N/A HIS 87.A ND1 ASP 90.A OD2 no hydrogen 3.113 N/A ASP 90.A N ASP 90.A OD1 no hydrogen 2.623 N/A GLY 91.A N HIS 87.A O no hydrogen 2.902 N/A VAL 93.A N LYS 68.A O no hydrogen 2.960 N/A ALA 94.A N LEU 66.A O no hydrogen 2.923 N/A ARG 95.A N THR 92.A OG1 no hydrogen 3.141 N/A ARG 95.A NH2 GLU 98.A OE1 no hydrogen 3.340 N/A LEU 96.A N THR 92.A O no hydrogen 2.891 N/A CYS 97.A N VAL 93.A O no hydrogen 2.906 N/A CYS 97.A SG VAL 93.A O no hydrogen 3.473 N/A GLU 98.A N ALA 94.A O no hydrogen 3.121 N/A ALA 99.A N ARG 95.A O no hydrogen 2.912 N/A ALA 100.A N LEU 96.A O no hydrogen 2.873 N/A ILE 101.A N CYS 97.A O no hydrogen 3.019 N/A THR 102.A N GLU 98.A O no hydrogen 2.786 N/A THR 102.A OG1 GLU 98.A O no hydrogen 2.769 N/A ARG 103.A N ALA 99.A O no hydrogen 3.161 N/A SER 104.A OG SER 44.A OG no hydrogen 3.073 N/A ASP 105.A N ALA 99.A O no hydrogen 3.108 N/A ASN 106.A N HIS 80.A O no hydrogen 2.926 N/A ASN 106.A ND2 GLU 79.A O no hydrogen 2.880 N/A THR 107.A N SER 81.A OG no hydrogen 3.380 N/A THR 107.A OG1 SER 81.A OG no hydrogen 2.566 N/A ALA 108.A N ASP 105.A OD1 no hydrogen 2.904 N/A ALA 109.A N ASP 105.A O no hydrogen 3.055 N/A ASN 110.A N ASN 106.A O no hydrogen 3.068 N/A ASN 110.A ND2 GLU 139.A O no hydrogen 3.067 N/A LEU 112.A N ALA 109.A O no hydrogen 2.959 N/A LYS 113.A N ASN 110.A O no hydrogen 2.989 N/A GLN 114.A N LEU 111.A O no hydrogen 2.920 N/A ILE 115.A N LEU 112.A O no hydrogen 3.077 N/A GLY 117.A N LEU 112.A O no hydrogen 2.808 N/A GLY 120.A N GLY 116.A O no hydrogen 3.216 N/A LEU 121.A N GLY 117.A O no hydrogen 2.975 N/A THR 122.A N PRO 118.A O no hydrogen 2.964 N/A THR 122.A OG1 PRO 118.A O no hydrogen 3.120 N/A THR 122.A OG1 LEU 135.A O no hydrogen 3.079 N/A ALA 123.A N ALA 119.A O no hydrogen 2.961 N/A TYR 124.A N GLY 120.A O no hydrogen 3.023 N/A PHE 125.A N LEU 121.A O no hydrogen 2.866 N/A HIS 126.A N THR 122.A O no hydrogen 3.101 N/A HIS 126.A ND1 THR 122.A O no hydrogen 3.114 N/A THR 127.A N ALA 123.A O no hydrogen 3.118 N/A THR 127.A OG1 TYR 124.A O no hydrogen 2.722 N/A LEU 128.A N TYR 124.A O no hydrogen 3.174 N/A LEU 128.A N PHE 125.A O no hydrogen 3.017 N/A LYS 129.A N HIS 126.A O no hydrogen 2.843 N/A ASP 130.A N PHE 125.A O no hydrogen 2.999 N/A VAL 132.A N ASP 130.A OD1 no hydrogen 2.842 N/A SER 133.A N ASP 130.A OD1 no hydrogen 2.954 N/A SER 133.A OG ASP 130.A OD1 no hydrogen 3.544 N/A SER 133.A OG ASP 130.A OD2 no hydrogen 2.622 N/A SER 133.A OG THR 154.A OG1 no hydrogen 2.629 N/A ARG 134.A N.A THR 153.A O no hydrogen 3.255 N/A ARG 134.A N.B THR 153.A O no hydrogen 3.220 N/A ARG 134.A NE.B ASP 136.A OD1 no hydrogen 3.347 N/A ARG 134.A NE.B ASP 136.A OD2 no hydrogen 2.698 N/A ARG 134.A NH1.B ASP 136.A OD1 no hydrogen 2.982 N/A ARG 134.A NH1.B ASP 136.A OD2 no hydrogen 3.465 N/A LEU 135.A N THR 122.A OG1 no hydrogen 2.960 N/A ASP 136.A N ASP 152.A OD1 no hydrogen 2.682 N/A ARG 137.A N ASP 152.A OD1 no hydrogen 2.914 N/A ARG 137.A NE ASP 152.A OD2 no hydrogen 2.694 N/A ARG 137.A NH2 ASN 144.A O no hydrogen 3.384 N/A ARG 137.A NH2 ASP 152.A OD2 no hydrogen 3.035 N/A GLU 139.A N ASN 110.A OD1 no hydrogen 2.948 N/A GLU 141.A N GLU 141.A OE1 no hydrogen 2.856 N/A LEU 142.A N TRP 138.A O no hydrogen 3.061 N/A ASN 143.A N THR 140.A O no hydrogen 3.042 N/A ASN 143.A ND2 GLU 139.A OE1 no hydrogen 2.776 N/A ASN 143.A ND2 THR 140.A O no hydrogen 3.295 N/A ASN 144.A N GLU 141.A O no hydrogen 3.093 N/A GLU 149.A N SER 146.A O no hydrogen 2.869 N/A ARG 151.A N GLU 149.A OE2 no hydrogen 2.912 N/A ARG 151.A NE GLU 149.A OE2 no hydrogen 2.825 N/A ARG 151.A NH2 GLU 149.A OE1 no hydrogen 3.094 N/A ASP 152.A N ASP 136.A OD2 no hydrogen 2.998 N/A THR 153.A OG1 LYS 150.A O no hydrogen 2.751 N/A THR 154.A N PHE 40.A O no hydrogen 2.875 N/A THR 154.A OG1 SER 133.A OG no hydrogen 2.629 N/A THR 154.A OG1 THR 155.A O no hydrogen 3.301 N/A THR 155.A OG1 SER 36.A O no hydrogen 3.421 N/A THR 155.A OG1 SER 158.A OG no hydrogen 2.905 N/A ALA 157.A N SER 36.A O no hydrogen 2.974 N/A SER 158.A N THR 155.A OG1 no hydrogen 2.984 N/A SER 158.A OG THR 155.A OG1 no hydrogen 2.905 N/A ARG 160.A N ALA 157.A O no hydrogen 2.892 N/A ASP 161.A N SER 158.A O no hydrogen 3.042 N/A ARG 163.A N GLY 159.A O no hydrogen 2.900 N/A ALA 164.A N ARG 160.A O no hydrogen 3.030 N/A VAL 165.A N ASP 161.A O no hydrogen 3.121 N/A THR 166.A N LEU 162.A O no hydrogen 2.915 N/A THR 166.A OG1 LEU 162.A O no hydrogen 2.736 N/A THR 167.A N ARG 163.A O no hydrogen 2.894 N/A THR 167.A OG1 ARG 163.A O no hydrogen 2.827 N/A GLY 168.A N ARG 163.A O no hydrogen 2.914 N/A ALA 170.A N ALA 164.A O no hydrogen 3.318 N/A ARG 174.A N ASP 172.A OD1 no hydrogen 2.740 N/A ARG 174.A NE ASP 172.A OD1 no hydrogen 3.063 N/A ARG 174.A NH2 ASP 172.A OD2 no hydrogen 2.908 N/A ARG 176.A N ASP 172.A O no hydrogen 2.765 N/A GLU 177.A N ALA 173.A O no hydrogen 2.963 N/A ARG 178.A N ARG 174.A O no hydrogen 3.036 N/A LEU 179.A N ASP 175.A O no hydrogen 2.850 N/A ASN 180.A N ARG 176.A O no hydrogen 2.909 N/A ASN 180.A ND2 THR 166.A O no hydrogen 3.014 N/A ALA 181.A N GLU 177.A O no hydrogen 2.960 N/A TRP 182.A N ARG 178.A O no hydrogen 3.136 N/A LEU 183.A N LEU 179.A O no hydrogen 2.987 N/A THR 184.A N ASN 180.A O no hydrogen 2.842 N/A THR 184.A OG1 ASN 180.A O no hydrogen 3.038 N/A THR 184.A OG1 ALA 181.A O no hydrogen 3.164 N/A ALA 185.A N ALA 181.A O no hydrogen 3.176 N/A ALA 185.A N TRP 182.A O no hydrogen 3.085 N/A ASN 186.A N LEU 183.A O no hydrogen 3.226 N/A ASN 186.A ND2 THR 188.A OG1 no hydrogen 3.209 N/A ASN 186.A ND2 ASP 205.A OD1 no hydrogen 2.948 N/A ASN 186.A ND2 ASP 205.A OD2 no hydrogen 3.215 N/A LYS 187.A N THR 102.A O no hydrogen 2.943 N/A LYS 187.A NZ ALA 185.A O no hydrogen 2.651 N/A THR 188.A N ASN 186.A OD1 no hydrogen 3.219 N/A THR 188.A OG1 ASN 186.A OD1 no hydrogen 3.215 N/A THR 188.A OG1 THR 207.A OG1 no hydrogen 2.678 N/A ARG 192.A N GLY 189.A O no hydrogen 3.215 N/A ARG 192.A NE ASP 247.A OD1 no hydrogen 2.691 N/A ARG 192.A NH1 GLY 208.A O no hydrogen 2.976 N/A ARG 192.A NH1 THR 209.A OG1 no hydrogen 3.048 N/A ARG 192.A NH1 ASN 217.A O no hydrogen 3.019 N/A ARG 192.A NH2 THR 209.A OG1 no hydrogen 2.868 N/A ARG 192.A NH2 ASP 247.A OD1 no hydrogen 3.052 N/A ILE 193.A N ASP 218.A OD2 no hydrogen 3.014 N/A ARG 194.A NE ASP 205.A OD1 no hydrogen 3.026 N/A ARG 194.A NH1 ASP 205.A OD1 no hydrogen 3.069 N/A ALA 195.A N ARG 192.A O no hydrogen 2.954 N/A GLY 196.A N ARG 192.A O no hydrogen 3.225 N/A GLY 196.A N ILE 193.A O no hydrogen 3.051 N/A TRP 201.A N PRO 198.A O no hydrogen 3.116 N/A THR 202.A N TRP 223.A O no hydrogen 3.318 N/A GLY 204.A N VAL 221.A O no hydrogen 2.851 N/A ASP 205.A N LEU 183.A O no hydrogen 3.171 N/A LYS 206.A N ILE 219.A O no hydrogen 2.884 N/A LYS 206.A NZ SER 104.A OG no hydrogen 2.915 N/A LYS 206.A NZ THR 207.A O no hydrogen 2.915 N/A THR 207.A OG1 THR 188.A OG1 no hydrogen 2.678 N/A GLY 208.A N ASN 217.A O no hydrogen 3.073 N/A ASN 210.A N ALA 215.A O no hydrogen 2.881 N/A TYR 213.A N ALA 241.A O no hydrogen 2.778 N/A GLY 214.A N SER 211.A O no hydrogen 2.930 N/A ALA 215.A N ASN 210.A O no hydrogen 2.908 N/A GLY 216.A N THR 236.A O no hydrogen 2.969 N/A ASN 217.A N GLY 208.A O no hydrogen 2.807 N/A ASN 217.A ND2 PRO 41.A O no hydrogen 2.938 N/A ASN 217.A ND2 LEU 42.A O no hydrogen 3.234 N/A ASP 218.A N ILE 234.A O no hydrogen 2.858 N/A ILE 219.A N LYS 206.A O no hydrogen 3.070 N/A VAL 221.A N GLY 204.A O no hydrogen 2.888 N/A VAL 222.A N ILE 231.A O no hydrogen 2.858 N/A TRP 223.A N THR 202.A O no hydrogen 2.834 N/A GLY 225.A N TRP 223.A O no hydrogen 2.869 N/A ILE 231.A N VAL 222.A O no hydrogen 2.860 N/A ILE 232.A N.A VAL 24.A O no hydrogen 2.981 N/A ILE 232.A N.B VAL 24.A O no hydrogen 2.997 N/A SER 233.A OG PRO 156.A O no hydrogen 2.801 N/A ILE 234.A N ASP 218.A O no hydrogen 2.913 N/A TYR 235.A N GLY 20.A O no hydrogen 2.833 N/A TYR 235.A OH THR 45.A OG1 no hydrogen 2.795 N/A THR 236.A N GLY 216.A O no hydrogen 2.917 N/A THR 236.A OG1 GLY 216.A O no hydrogen 2.718 N/A ASN 237.A N ARG 18.A O no hydrogen 3.075 N/A ASN 237.A ND2 ARG 238.A O no hydrogen 2.966 N/A ARG 238.A N TYR 213.A O no hydrogen 2.711 N/A ARG 238.A NE PHE 15.A O no hydrogen 3.305 N/A ARG 238.A NH1 PHE 15.A O no hydrogen 2.768 N/A ARG 238.A NH2 ALA 244.A O no hydrogen 2.790 N/A ALA 243.A N ALA 240.A O no hydrogen 3.124 N/A LYS 248.A NZ ASP 252.A OD1 no hydrogen 2.742 N/A LYS 248.A NZ ASP 252.A OD2 no hydrogen 3.202 N/A VAL 249.A N ASP 246.A OD2 no hydrogen 3.221 N/A ALA 251.A N ASP 247.A O no hydrogen 2.972 N/A ASP 252.A N LYS 248.A O no hydrogen 2.830 N/A THR 253.A N VAL 249.A O no hydrogen 2.901 N/A THR 253.A OG1 VAL 249.A O no hydrogen 2.791 N/A ALA 254.A N ILE 250.A O no hydrogen 3.020 N/A ALA 255.A N ALA 251.A O no hydrogen 3.173 N/A ILE 256.A N ASP 252.A O no hydrogen 3.016 N/A LEU 257.A N THR 253.A O no hydrogen 2.923 N/A ALA 258.A N ALA 254.A O no hydrogen 2.961 N/A ARG 259.A N ALA 255.A O no hydrogen 2.943 N/A ARG 259.A NH2 GLU 7.A OE1 no hydrogen 3.294 N/A ALA 260.A N ILE 256.A O no hydrogen 2.895 N/A LEU 261.A N LEU 257.A O no hydrogen 3.050 N/A GLY 262.A N ARG 259.A O no hydrogen 2.865 N/A LYS 263.A N ALA 258.A O no hydrogen 2.992 N/A LYS 263.A NZ ASP 25.A OD2 no hydrogen 2.728 N/A