Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5e6j_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 3.A N VAL 19.A O no hydrogen 2.830 N/A VAL 5.A N GLN 17.A O no hydrogen 2.830 N/A PHE 6.A N LYS 51.A O no hydrogen 3.391 N/A THR 7.A N HIS 15.A O no hydrogen 2.792 N/A THR 7.A OG1 HIS 15.A O no hydrogen 3.324 N/A THR 8.A N PHE 53.A O no hydrogen 2.732 N/A THR 8.A OG1 ASN 13.A O no hydrogen 2.735 N/A ASP 10.A N THR 8.A OG1 no hydrogen 3.247 N/A ASN 11.A N THR 8.A OG1 no hydrogen 3.095 N/A THR 12.A N ASP 10.A OD1 no hydrogen 2.884 N/A THR 12.A OG1 ASP 10.A O no hydrogen 3.004 N/A ASN 13.A N ASP 10.A OD1 no hydrogen 2.849 N/A ASN 13.A ND2 ASP 10.A OD2 no hydrogen 2.843 N/A HIS 15.A N THR 7.A O no hydrogen 2.838 N/A HIS 15.A NE2 GLU 65.A OE1 no hydrogen 3.053 N/A HIS 15.A NE2 GLU 65.A OE2 no hydrogen 2.954 N/A GLN 17.A N VAL 5.A O no hydrogen 2.793 N/A VAL 19.A N ILE 3.A O no hydrogen 2.591 N/A ASP 20.A N GLN 28.A OE1 no hydrogen 2.830 N/A SER 22.A N ASP 20.A OD1 no hydrogen 2.864 N/A SER 22.A OG ASP 20.A OD1 no hydrogen 2.582 N/A THR 24.A OG1 THR 40.A O no hydrogen 2.725 N/A THR 24.A OG1 ILE 42.A O no hydrogen 2.649 N/A GLY 26.A N THR 40.A O no hydrogen 2.868 N/A GLN 27.A N THR 24.A O no hydrogen 3.238 N/A GLN 28.A N TYR 25.A O no hydrogen 2.849 N/A GLN 28.A NE2 ASP 20.A O no hydrogen 3.555 N/A GLN 28.A NE2 THR 24.A O no hydrogen 2.780 N/A PHE 29.A N TYR 25.A O no hydrogen 2.826 N/A THR 32.A N THR 40.A OG1 no hydrogen 2.858 N/A TYR 33.A N PHE 54.A O no hydrogen 2.703 N/A LEU 34.A N ALA 37.A O no hydrogen 2.782 N/A ALA 37.A N LEU 34.A O no hydrogen 3.057 N/A VAL 39.A N THR 32.A O no hydrogen 3.357 N/A THR 40.A OG1 THR 32.A O no hydrogen 3.239 N/A THR 40.A OG1 ASP 38.A OD1 no hydrogen 2.798 N/A THR 40.A OG1 ASP 38.A OD2 no hydrogen 3.560 N/A HIS 48.A N HIS 45.A O no hydrogen 3.428 N/A GLU 49.A N VAL 46.A O no hydrogen 3.264 N/A GLY 50.A N LYS 4.A O no hydrogen 3.286 N/A LYS 51.A N HIS 48.A O no hydrogen 3.388 N/A PHE 53.A N PHE 6.A O no hydrogen 2.711 N/A PHE 54.A N TYR 33.A O no hydrogen 2.730 N/A VAL 55.A N THR 8.A O no hydrogen 3.116 N/A THR 61.A OG1 ASP 59.A OD1 no hydrogen 2.708 N/A LEU 62.A N ASP 59.A OD1 no hydrogen 2.891 N/A ARG 63.A N ASP 59.A O no hydrogen 2.779 N/A ARG 63.A NH2 ASP 60.A OD1 no hydrogen 2.631 N/A SER 64.A N ASP 60.A O no hydrogen 2.826 N/A GLU 65.A N THR 61.A O no hydrogen 2.842 N/A ALA 66.A N LEU 62.A O no hydrogen 2.822 N/A PHE 67.A N ARG 63.A O no hydrogen 2.862 N/A GLU 68.A N SER 64.A O no hydrogen 2.854 N/A TYR 69.A N GLU 65.A O no hydrogen 2.732 N/A TYR 70.A N ALA 66.A O no hydrogen 2.820 N/A HIS 71.A N PHE 67.A O no hydrogen 2.649 N/A ASP 74.A N THR 72.A OG1 no hydrogen 3.367 N/A SER 76.A N ASP 74.A OD1 no hydrogen 3.449 N/A SER 76.A OG ASP 74.A OD1 no hydrogen 2.929 N/A SER 76.A OG ASP 74.A OD2 no hydrogen 2.822 N/A PHE 77.A N ASP 74.A O no hydrogen 3.464 N/A GLY 79.A N SER 76.A O no hydrogen 3.258 N/A ARG 80.A NH1 ASP 74.A OD2 no hydrogen 2.662 N/A ARG 80.A NH2 ASP 74.A OD2 no hydrogen 3.488 N/A ARG 80.A NH2 ALA 151.A O no hydrogen 3.187 N/A TYR 81.A N PHE 77.A O no hydrogen 2.870 N/A MET 82.A N LEU 78.A O no hydrogen 2.827 N/A SER 83.A N GLY 79.A O no hydrogen 2.839 N/A SER 83.A OG GLY 79.A O no hydrogen 2.787 N/A ALA 84.A N ARG 80.A O no hydrogen 2.814 N/A LEU 85.A N TYR 81.A O no hydrogen 2.796 N/A ASN 86.A N MET 82.A O no hydrogen 2.857 N/A HIS 87.A N ALA 84.A O no hydrogen 2.915 N/A HIS 87.A ND1 SER 83.A O no hydrogen 3.305 N/A THR 88.A N ALA 84.A O no hydrogen 2.855 N/A THR 88.A OG1 ALA 84.A O no hydrogen 3.561 N/A THR 88.A OG1 LEU 85.A O no hydrogen 3.306 N/A THR 88.A OG1 ALA 143.A O no hydrogen 2.830 N/A LYS 89.A N LEU 85.A O no hydrogen 2.858 N/A LYS 89.A NZ ASN 86.A OD1 no hydrogen 3.508 N/A LYS 90.A N HIS 87.A O no hydrogen 2.969 N/A LYS 90.A NZ ASN 86.A O no hydrogen 3.000 N/A TRP 91.A N THR 88.A O no hydrogen 3.138 N/A TRP 91.A NE1 ASP 106.A OD2 no hydrogen 3.054 N/A GLN 95.A NE2 THR 100.A OG1 no hydrogen 3.253 N/A VAL 96.A N LEU 99.A O no hydrogen 2.611 N/A THR 100.A N GLN 119.A OE1 no hydrogen 2.720 N/A THR 100.A OG1 GLN 95.A OE1 no hydrogen 3.189 N/A THR 100.A OG1 GLN 119.A OE1 no hydrogen 3.294 N/A THR 100.A OG1 ALA 137.A O no hydrogen 3.057 N/A SER 101.A N PRO 94.A O no hydrogen 2.991 N/A SER 101.A OG SER 112.A OG no hydrogen 3.103 N/A SER 101.A OG GLY 285.A O no hydrogen 2.586 N/A ILE 102.A N SER 101.A OG no hydrogen 2.502 N/A LYS 103.A N LYS 92.A O no hydrogen 2.949 N/A ALA 105.A N ASN 108.A OD1 no hydrogen 3.266 N/A ASN 107.A ND2 GLY 158.A O no hydrogen 2.745 N/A ASN 108.A ND2 LYS 103.A O no hydrogen 2.829 N/A TYR 110.A OH GLU 159.A O no hydrogen 3.392 N/A SER 112.A N ASN 108.A O no hydrogen 2.744 N/A SER 112.A OG SER 101.A OG no hydrogen 3.103 N/A SER 113.A N CYS 109.A O no hydrogen 2.790 N/A SER 113.A OG CYS 109.A O no hydrogen 2.817 N/A VAL 114.A N TYR 110.A O no hydrogen 2.842 N/A LEU 115.A N LEU 111.A O no hydrogen 2.846 N/A LEU 116.A N SER 112.A O no hydrogen 2.870 N/A ALA 117.A N SER 113.A O no hydrogen 2.828 N/A LEU 118.A N VAL 114.A O no hydrogen 2.799 N/A GLN 119.A N LEU 115.A O no hydrogen 2.911 N/A GLN 119.A NE2 THR 100.A O no hydrogen 2.521 N/A GLN 119.A NE2 LEU 115.A O no hydrogen 3.489 N/A GLN 120.A N ALA 117.A O no hydrogen 2.989 N/A GLN 120.A NE2 LEU 116.A O no hydrogen 3.311 N/A LEU 121.A N LEU 118.A O no hydrogen 3.059 N/A PHE 125.A N GLN 131.A OE1 no hydrogen 2.692 N/A ASN 126.A N HIS 173.A O no hydrogen 2.842 N/A ALA 129.A N TYR 69.A O no hydrogen 3.484 N/A GLN 131.A N ALA 127.A O no hydrogen 2.910 N/A GLN 131.A NE2 GLN 131.A O no hydrogen 3.369 N/A GLU 132.A N PRO 128.A O no hydrogen 2.898 N/A ALA 133.A N ALA 129.A O no hydrogen 2.851 N/A TYR 134.A N LEU 130.A O no hydrogen 2.797 N/A TYR 134.A OH LEU 118.A O no hydrogen 2.537 N/A TYR 135.A N GLN 131.A O no hydrogen 2.876 N/A ARG 136.A N GLU 132.A O no hydrogen 2.855 N/A ARG 136.A NH2 ASP 141.A OD2 no hydrogen 2.874 N/A ALA 137.A N ALA 133.A O no hydrogen 2.745 N/A ARG 138.A N TYR 134.A O no hydrogen 2.831 N/A ALA 139.A N TYR 135.A O no hydrogen 2.858 N/A GLY 140.A N ARG 136.A O no hydrogen 2.970 N/A ASP 141.A N ARG 136.A O no hydrogen 2.787 N/A CYS 146.A N ALA 142.A O no hydrogen 3.027 N/A CYS 146.A SG ALA 142.A O no hydrogen 3.330 N/A ALA 147.A N ALA 143.A O no hydrogen 2.908 N/A LEU 148.A N ASN 144.A O no hydrogen 2.825 N/A ILE 149.A N PHE 145.A O no hydrogen 2.791 N/A LEU 150.A N CYS 146.A O no hydrogen 2.868 N/A ALA 151.A N ALA 147.A O no hydrogen 2.848 N/A TYR 152.A N LEU 148.A O no hydrogen 2.784 N/A TYR 152.A OH TYR 70.A O no hydrogen 2.929 N/A SER 153.A N ILE 149.A O no hydrogen 3.168 N/A SER 153.A N LEU 150.A O no hydrogen 3.335 N/A SER 153.A OG ILE 149.A O no hydrogen 2.775 N/A ASN 154.A N ALA 151.A O no hydrogen 3.188 N/A LYS 155.A N LEU 150.A O no hydrogen 3.127 N/A LYS 155.A NZ LEU 160.A O no hydrogen 2.933 N/A THR 156.A OG1 GLU 159.A OE1 no hydrogen 2.976 N/A GLU 159.A N THR 156.A O no hydrogen 3.332 N/A VAL 163.A N TYR 271.A OH no hydrogen 3.259 N/A ARG 164.A N ASP 162.A OD1 no hydrogen 2.826 N/A THR 166.A N ASP 162.A O no hydrogen 3.291 N/A THR 166.A OG1 ASP 162.A O no hydrogen 3.033 N/A MET 167.A N VAL 163.A O no hydrogen 2.829 N/A THR 168.A N ARG 164.A O no hydrogen 2.859 N/A THR 168.A OG1 ARG 164.A O no hydrogen 2.893 N/A HIS 169.A N GLU 165.A O no hydrogen 2.863 N/A LEU 170.A N THR 166.A O no hydrogen 2.795 N/A LEU 171.A N MET 167.A O no hydrogen 2.825 N/A GLN 172.A N THR 168.A O no hydrogen 2.868 N/A HIS 173.A N LEU 170.A O no hydrogen 2.774 N/A ALA 174.A N LEU 171.A O no hydrogen 2.975 N/A ASN 175.A N LYS 124.A O no hydrogen 2.662 N/A LEU 176.A N ALA 174.A O no hydrogen 3.212 N/A ALA 179.A N LEU 176.A O no hydrogen 3.146 N/A LYS 180.A N GLU 236.A O no hydrogen 2.819 N/A ARG 181.A N LEU 197.A O no hydrogen 2.851 N/A ARG 181.A NE GLN 235.A OE1 no hydrogen 2.739 N/A ARG 181.A NH1 MET 204.A O no hydrogen 3.098 N/A VAL 182.A N GLN 234.A O no hydrogen 2.823 N/A LEU 183.A N THR 195.A O no hydrogen 2.806 N/A ASN 184.A N TYR 231.A O no hydrogen 3.228 N/A VAL 185.A N LYS 193.A O no hydrogen 2.839 N/A VAL 186.A N THR 229.A O no hydrogen 3.330 N/A CYS 187.A N GLY 191.A O no hydrogen 3.348 N/A GLN 192.A NE2 ASN 184.A OD1 no hydrogen 3.191 N/A LYS 193.A N VAL 185.A O no hydrogen 2.772 N/A LYS 193.A NZ CYS 190.A O no hydrogen 2.277 N/A LYS 193.A NZ GLN 192.A O no hydrogen 3.276 N/A THR 194.A OG1 LEU 183.A O no hydrogen 3.036 N/A THR 195.A N LEU 183.A O no hydrogen 2.834 N/A LEU 197.A N ARG 181.A O no hydrogen 2.743 N/A GLY 199.A N ALA 179.A O no hydrogen 3.301 N/A GLU 201.A N GLU 201.A OE1 no hydrogen 2.477 N/A ALA 202.A N GLY 199.A O no hydrogen 2.836 N/A VAL 203.A N VAL 200.A O no hydrogen 3.233 N/A TYR 205.A N MET 241.A O no hydrogen 3.114 N/A TYR 205.A OH GLN 230.A OE1 no hydrogen 2.624 N/A GLY 207.A N SER 243.A O no hydrogen 2.909 N/A SER 210.A N THR 208.A OG1 no hydrogen 3.204 N/A TYR 211.A OH GLU 305.A OE2 no hydrogen 2.944 N/A ASN 213.A N SER 210.A OG no hydrogen 2.781 N/A LEU 214.A N TYR 211.A O no hydrogen 3.146 N/A LYS 215.A N ASP 212.A O no hydrogen 2.739 N/A THR 216.A N ASP 212.A O no hydrogen 2.749 N/A THR 216.A OG1 ASP 212.A O no hydrogen 3.234 N/A GLY 217.A N ASN 213.A O no hydrogen 3.088 N/A VAL 218.A N GLN 230.A O no hydrogen 2.702 N/A ILE 220.A N ALA 228.A O no hydrogen 2.830 N/A GLY 225.A N VAL 223.A O no hydrogen 2.834 N/A ARG 226.A N CYS 224.A O no hydrogen 2.574 N/A ALA 228.A N ILE 220.A O no hydrogen 2.743 N/A THR 229.A N VAL 186.A O no hydrogen 3.125 N/A GLN 230.A N VAL 218.A O no hydrogen 2.834 N/A TYR 231.A N ASN 184.A O no hydrogen 3.286 N/A LEU 232.A N LEU 214.A O no hydrogen 2.643 N/A VAL 233.A N VAL 182.A O no hydrogen 2.869 N/A GLN 234.A N VAL 182.A O no hydrogen 2.915 N/A GLN 235.A N TYR 308.A O no hydrogen 3.375 N/A GLN 235.A NE2 ALA 202.A O no hydrogen 2.663 N/A GLN 235.A NE2 SER 237.A OG no hydrogen 3.143 N/A GLU 236.A N LYS 180.A O no hydrogen 2.726 N/A SER 237.A OG PHE 239.A O no hydrogen 2.762 N/A SER 238.A OG GLU 122.A O no hydrogen 3.375 N/A VAL 240.A N TYR 303.A O no hydrogen 2.749 N/A MET 241.A N VAL 203.A O no hydrogen 2.887 N/A MET 242.A N VAL 301.A O no hydrogen 2.827 N/A SER 243.A N TYR 205.A O no hydrogen 2.664 N/A SER 243.A OG ASP 300.A OD1 no hydrogen 2.596 N/A ALA 244.A N THR 299.A O no hydrogen 2.908 N/A ALA 247.A N VAL 298.A O no hydrogen 3.280 N/A TYR 249.A N GLY 296.A O no hydrogen 2.795 N/A LEU 251.A N TYR 294.A O no hydrogen 2.821 N/A THR 255.A OG1 GLN 252.A O no hydrogen 2.967 N/A LEU 257.A N PHE 302.A O no hydrogen 2.836 N/A ALA 259.A N ILE 274.A O no hydrogen 2.748 N/A ASN 260.A N ASP 300.A O no hydrogen 2.623 N/A GLU 261.A N THR 272.A O no hydrogen 2.830 N/A TYR 262.A N PRO 297.A O no hydrogen 3.090 N/A TYR 262.A OH ASN 265.A O no hydrogen 2.875 N/A THR 263.A N HIS 270.A O no hydrogen 2.831 N/A THR 263.A OG1 HIS 270.A O no hydrogen 2.978 N/A ASN 265.A N CYS 268.A O no hydrogen 3.265 N/A GLN 267.A N ASN 265.A OD1 no hydrogen 3.018 N/A CYS 268.A N ASN 265.A OD1 no hydrogen 2.773 N/A HIS 270.A N THR 263.A O no hydrogen 2.770 N/A THR 272.A N GLU 261.A O no hydrogen 2.821 N/A THR 272.A OG1 GLU 261.A OE1 no hydrogen 2.578 N/A HIS 273.A N ILE 283.A O no hydrogen 2.875 N/A HIS 273.A ND1 ASN 260.A OD1 no hydrogen 2.981 N/A ILE 274.A N ALA 259.A O no hydrogen 2.808 N/A THR 275.A N TYR 281.A O no hydrogen 2.838 N/A THR 275.A OG1 GLN 120.A OE1 no hydrogen 2.480 N/A ALA 276.A N LEU 257.A O no hydrogen 3.385 N/A LYS 277.A N THR 279.A O no hydrogen 3.195 N/A THR 279.A OG1 MET 291.A O no hydrogen 2.243 N/A LEU 280.A N THR 279.A OG1 no hydrogen 2.618 N/A LEU 280.A N MET 291.A O no hydrogen 2.822 N/A TYR 281.A N THR 275.A O no hydrogen 2.798 N/A ARG 282.A N THR 289.A O no hydrogen 2.807 N/A ILE 283.A N HIS 273.A O no hydrogen 2.749 N/A ASP 284.A N HIS 287.A O no hydrogen 2.798 N/A HIS 287.A N ASP 284.A O no hydrogen 2.821 N/A THR 289.A N ARG 282.A O no hydrogen 2.817 N/A TYR 294.A OH GLU 261.A OE2 no hydrogen 2.347 N/A GLY 296.A N TYR 249.A O no hydrogen 3.350 N/A VAL 298.A N ALA 247.A O no hydrogen 2.756 N/A THR 299.A N ASN 260.A O no hydrogen 2.876 N/A THR 299.A OG1 ALA 244.A O no hydrogen 3.110 N/A THR 299.A OG1 ASP 300.A OD1 no hydrogen 3.245 N/A ASP 300.A N ASN 260.A O no hydrogen 3.317 N/A VAL 301.A N MET 242.A O no hydrogen 2.814 N/A PHE 302.A N CYS 258.A O no hydrogen 2.665 N/A TYR 303.A N VAL 240.A O no hydrogen 2.786 N/A TYR 303.A OH LEU 209.A O no hydrogen 2.549 N/A GLU 305.A N SER 238.A O no hydrogen 2.985 N/A THR 306.A N GLU 305.A OE1 no hydrogen 3.000 N/A THR 310.A OG1 VAL 233.A O no hydrogen 3.104 N/A