Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5e8o_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): HIS 3.A N LEU 103.A O no hydrogen 2.928 N/A HIS 3.A ND1 ASP 29.A OD2 no hydrogen 2.709 N/A SER 4.A N ASP 29.A OD1 no hydrogen 2.820 N/A MET 5.A N CYS 101.A O no hydrogen 2.962 N/A ARG 6.A N TYR 27.A O no hydrogen 3.007 N/A ARG 6.A NH1 MET 5.A O no hydrogen 3.001 N/A ARG 6.A NH1 CYS 101.A O no hydrogen 3.303 N/A ARG 6.A NH1 ASP 102.A OD1 no hydrogen 2.927 N/A ARG 6.A NH2 ASP 102.A OD1 no hydrogen 2.799 N/A ARG 6.A NH2 ASP 102.A OD2 no hydrogen 3.463 N/A TYR 7.A N SER 99.A O no hydrogen 2.919 N/A PHE 8.A N VAL 25.A O no hydrogen 2.706 N/A GLU 9.A N GLN 97.A O no hydrogen 2.739 N/A THR 10.A N ILE 23.A O no hydrogen 2.827 N/A ALA 11.A N LEU 95.A O no hydrogen 2.901 N/A VAL 12.A N ARG 21.A O no hydrogen 2.925 N/A SER 13.A N HIS 93.A O no hydrogen 2.888 N/A SER 13.A OG HIS 93.A O no hydrogen 3.516 N/A LEU 17.A N ARG 14.A O no hydrogen 3.300 N/A ARG 21.A N VAL 12.A O no hydrogen 2.944 N/A ARG 21.A NE ASP 37.A OD1 no hydrogen 3.042 N/A ARG 21.A NH2 ASP 37.A OD2 no hydrogen 2.685 N/A TYR 22.A N SER 38.A OG no hydrogen 2.817 N/A TYR 22.A OH GLU 9.A OE1 no hydrogen 2.536 N/A ILE 23.A N THR 10.A O no hydrogen 2.853 N/A SER 24.A N PHE 36.A O no hydrogen 2.873 N/A SER 24.A OG TYR 45.A OH no hydrogen 2.733 N/A VAL 25.A N PHE 8.A O no hydrogen 2.913 N/A GLY 26.A N VAL 34.A O no hydrogen 3.120 N/A TYR 27.A N ARG 6.A O no hydrogen 2.534 N/A VAL 28.A N LYS 31.A O no hydrogen 3.005 N/A ASP 29.A N SER 4.A O no hydrogen 2.849 N/A LYS 31.A N VAL 28.A O no hydrogen 2.971 N/A PHE 33.A N GLY 26.A O no hydrogen 2.913 N/A ARG 35.A N GLU 46.A O no hydrogen 3.122 N/A ARG 35.A NE GLU 32.A OE2 no hydrogen 2.950 N/A ARG 35.A NH1 GLU 32.A OE1 no hydrogen 2.952 N/A ARG 35.A NH1 GLU 32.A OE2 no hydrogen 3.486 N/A PHE 36.A N SER 24.A O no hydrogen 2.795 N/A SER 38.A N TYR 22.A O no hydrogen 2.822 N/A SER 38.A OG TYR 22.A O no hydrogen 3.308 N/A ASP 39.A N ASP 37.A OD1 no hydrogen 2.829 N/A ALA 40.A N ASP 37.A O no hydrogen 3.113 N/A ARG 44.A NE GLU 46.A OE2 no hydrogen 2.839 N/A ARG 44.A NH2 GLU 46.A OE2 no hydrogen 3.439 N/A TYR 45.A N THR 64.A OG1 no hydrogen 2.993 N/A TYR 45.A OH SER 24.A OG no hydrogen 2.733 N/A GLU 46.A N ARG 35.A O no hydrogen 2.953 N/A ARG 48.A N PHE 33.A O no hydrogen 2.851 N/A MET 52.A N ALA 49.A O no hydrogen 2.932 N/A GLU 53.A N PRO 50.A O no hydrogen 3.016 N/A GLU 55.A N MET 52.A O no hydrogen 3.033 N/A TYR 59.A OH TYR 171.A OH no hydrogen 2.637 N/A TRP 60.A NE1 GLU 55.A O no hydrogen 2.981 N/A GLU 61.A N PRO 57.A O no hydrogen 2.950 N/A ARG 62.A N GLU 58.A O no hydrogen 2.959 N/A ARG 62.A NH1 GLU 63.A OE2 no hydrogen 2.823 N/A GLU 63.A N TYR 59.A O no hydrogen 2.924 N/A THR 64.A N TRP 60.A O no hydrogen 2.820 N/A THR 64.A OG1 TRP 60.A O no hydrogen 2.805 N/A GLN 65.A N GLU 61.A O no hydrogen 2.999 N/A LYS 66.A N ARG 62.A O no hydrogen 3.031 N/A LYS 66.A NZ GLU 63.A OE1 no hydrogen 3.541 N/A LYS 66.A NZ GLU 63.A OE2 no hydrogen 3.347 N/A ALA 67.A N GLU 63.A O no hydrogen 3.036 N/A LYS 68.A N THR 64.A O no hydrogen 3.034 N/A GLY 69.A N GLN 65.A O no hydrogen 3.230 N/A GLN 70.A N LYS 66.A O no hydrogen 2.863 N/A GLU 71.A N ALA 67.A O no hydrogen 2.814 N/A GLN 72.A N LYS 68.A O no hydrogen 3.321 N/A TRP 73.A N GLY 69.A O no hydrogen 2.979 N/A PHE 74.A N GLN 70.A O no hydrogen 2.811 N/A ARG 75.A N GLU 71.A O no hydrogen 2.971 N/A ARG 75.A NH1 GLU 71.A OE2 no hydrogen 3.339 N/A VAL 76.A N GLN 72.A O no hydrogen 3.096 N/A SER 77.A N TRP 73.A O no hydrogen 2.984 N/A SER 77.A OG TRP 73.A O no hydrogen 2.923 N/A LEU 78.A N PHE 74.A O no hydrogen 2.779 N/A ARG 79.A N ARG 75.A O no hydrogen 3.055 N/A ASN 80.A N VAL 76.A O no hydrogen 2.864 N/A LEU 81.A N SER 77.A O no hydrogen 2.925 N/A LEU 82.A N LEU 78.A O no hydrogen 3.163 N/A TYR 84.A N ASN 80.A O no hydrogen 2.999 N/A TYR 85.A N LEU 81.A O no hydrogen 3.069 N/A TYR 85.A OH ASP 137.A OD2 no hydrogen 2.509 N/A ASN 86.A N GLY 83.A O no hydrogen 3.099 N/A GLN 87.A N LEU 82.A O no hydrogen 2.934 N/A GLN 87.A NE2 GLU 119.A OE2 no hydrogen 2.863 N/A HIS 93.A N SER 13.A O no hydrogen 2.867 N/A HIS 93.A ND1 GLU 119.A OE2 no hydrogen 2.705 N/A THR 94.A N GLU 119.A OE1 no hydrogen 3.064 N/A LEU 95.A N ALA 11.A O no hydrogen 2.943 N/A GLN 96.A N ALA 117.A O no hydrogen 2.904 N/A GLN 97.A N GLU 9.A O no hydrogen 2.833 N/A MET 98.A N GLN 115.A O no hydrogen 3.041 N/A SER 99.A N TYR 7.A O no hydrogen 3.196 N/A GLY 100.A N TYR 113.A O no hydrogen 3.102 N/A CYS 101.A N MET 5.A O no hydrogen 3.007 N/A ASP 102.A N ARG 111.A O no hydrogen 2.849 N/A LEU 103.A N HIS 3.A O no hydrogen 2.495 N/A GLY 104.A N ARG 108.A O no hydrogen 2.766 N/A TRP 107.A N GLY 104.A O no hydrogen 2.860 N/A ARG 108.A N ASP 106.A OD1 no hydrogen 3.050 N/A LEU 110.A N ASP 102.A O no hydrogen 2.760 N/A TYR 113.A N GLY 100.A O no hydrogen 2.821 N/A TYR 113.A OH ASP 102.A OD2 no hydrogen 2.631 N/A GLN 115.A N MET 98.A O no hydrogen 2.880 N/A PHE 116.A N ILE 124.A O no hydrogen 2.782 N/A ALA 117.A N GLN 96.A O no hydrogen 2.912 N/A TYR 118.A N ARG 121.A O no hydrogen 2.901 N/A TYR 118.A OH GLN 87.A OE1 no hydrogen 2.626 N/A GLU 119.A N THR 94.A O no hydrogen 2.831 N/A ARG 121.A N TYR 118.A O no hydrogen 3.048 N/A TYR 123.A N PHE 116.A O no hydrogen 2.864 N/A TYR 123.A OH THR 143.A OG1 no hydrogen 2.723 N/A ALA 125.A N THR 134.A O no hydrogen 2.960 N/A LEU 126.A N LEU 114.A O no hydrogen 2.798 N/A ASN 127.A N THR 132.A O no hydrogen 2.767 N/A ASN 127.A ND2 THR 132.A OG1 no hydrogen 2.818 N/A LEU 130.A N ASN 127.A O no hydrogen 2.729 N/A LYS 131.A N ASP 129.A OD1 no hydrogen 3.121 N/A THR 132.A N ASP 129.A OD1 no hydrogen 3.200 N/A THR 132.A OG1 ASP 129.A OD1 no hydrogen 3.263 N/A THR 132.A OG1 ASP 129.A OD2 no hydrogen 2.858 N/A THR 134.A N ALA 125.A O no hydrogen 2.904 N/A THR 134.A OG1 ASN 127.A OD1 no hydrogen 2.469 N/A ALA 140.A N ASP 137.A O no hydrogen 3.171 N/A GLN 141.A N MET 138.A O no hydrogen 3.331 N/A GLN 141.A NE2 ALA 135.A O no hydrogen 2.687 N/A GLN 141.A NE2 ALA 136.A O no hydrogen 3.633 N/A GLN 141.A NE2 ASP 137.A O no hydrogen 2.850 N/A ILE 142.A N ALA 139.A O no hydrogen 3.402 N/A THR 143.A OG1 TYR 123.A OH no hydrogen 2.723 N/A ARG 144.A N ALA 140.A O no hydrogen 3.059 N/A ARG 144.A NE GLN 141.A OE1 no hydrogen 2.859 N/A ARG 144.A NH1 GLU 148.A OE2 no hydrogen 3.302 N/A ARG 144.A NH2 GLN 141.A OE1 no hydrogen 2.370 N/A ARG 145.A N GLN 141.A O no hydrogen 2.935 N/A LYS 146.A N ILE 142.A O no hydrogen 3.044 N/A TRP 147.A N THR 143.A O no hydrogen 2.826 N/A GLU 148.A N ARG 144.A O no hydrogen 2.696 N/A GLN 149.A N ARG 145.A O no hydrogen 2.942 N/A SER 150.A N LYS 146.A O no hydrogen 3.118 N/A SER 150.A OG LYS 146.A O no hydrogen 3.213 N/A SER 150.A OG TRP 147.A O no hydrogen 3.374 N/A GLY 151.A N GLU 148.A O no hydrogen 3.173 N/A ALA 152.A N TRP 147.A O no hydrogen 3.197 N/A GLU 154.A N GLY 151.A O no hydrogen 3.065 N/A TYR 156.A N ALA 152.A O no hydrogen 3.326 N/A LYS 157.A N ALA 153.A O no hydrogen 2.762 N/A LYS 157.A NZ GLU 161.A OE1 no hydrogen 2.689 N/A LYS 157.A NZ GLU 161.A OE2 no hydrogen 2.971 N/A ALA 158.A N GLU 154.A O no hydrogen 3.012 N/A TYR 159.A N HIS 155.A O no hydrogen 2.962 N/A LEU 160.A N TYR 156.A O no hydrogen 2.854 N/A GLU 161.A N LYS 157.A O no hydrogen 2.955 N/A GLY 162.A N ALA 158.A O no hydrogen 2.842 N/A GLY 162.A N TYR 159.A O no hydrogen 3.122 N/A CYS 164.A N TYR 159.A O no hydrogen 2.886 N/A GLU 166.A N GLY 162.A O no hydrogen 2.829 N/A TRP 167.A N GLU 163.A O no hydrogen 2.765 N/A LEU 168.A N CYS 164.A O no hydrogen 3.089 N/A HIS 169.A N VAL 165.A O no hydrogen 2.947 N/A HIS 169.A NE2 TRP 107.A O no hydrogen 2.705 N/A ARG 170.A N GLU 166.A O no hydrogen 3.175 N/A ARG 170.A NE GLU 55.A OE2 no hydrogen 2.771 N/A ARG 170.A NH2 GLU 55.A OE1 no hydrogen 2.811 N/A ARG 170.A NH2 GLU 55.A OE2 no hydrogen 3.133 N/A TYR 171.A N TRP 167.A O no hydrogen 2.834 N/A TYR 171.A OH TYR 59.A OH no hydrogen 2.637 N/A LEU 172.A N LEU 168.A O no hydrogen 2.806 N/A LYS 173.A N HIS 169.A O no hydrogen 3.092 N/A ASN 174.A N ARG 170.A O no hydrogen 3.037 N/A GLY 175.A N TYR 171.A O no hydrogen 2.919 N/A ASP 179.A N TYR 205.A O no hydrogen 3.006 N/A LYS 182.A N LEU 202.A O no hydrogen 2.808 N/A LYS 182.A NZ SER 180.A O no hydrogen 3.431 N/A HIS 184.A N TRP 200.A O no hydrogen 3.114 N/A THR 186.A N ARG 198.A O no hydrogen 3.018 N/A THR 186.A OG1 HIS 188.A NE2 no hydrogen 2.859 N/A THR 186.A OG1 ARG 198.A O no hydrogen 3.479 N/A HIS 188.A N THR 196.A O no hydrogen 2.956 N/A THR 196.A N HIS 188.A O no hydrogen 3.315 N/A THR 196.A OG1 HIS 188.A O no hydrogen 3.154 N/A LEU 197.A N VAL 243.A O no hydrogen 2.812 N/A ARG 198.A N THR 186.A O no hydrogen 2.959 N/A ARG 198.A NH2 SER 242.A OG no hydrogen 3.278 N/A CYS 199.A N ALA 241.A O no hydrogen 2.798 N/A TRP 200.A N HIS 184.A O no hydrogen 2.899 N/A ALA 201.A N LYS 239.A O no hydrogen 2.801 N/A LEU 202.A N LYS 182.A O no hydrogen 2.875 N/A TYR 205.A N ASP 179.A O no hydrogen 2.918 N/A THR 210.A N TYR 258.A O no hydrogen 2.847 N/A THR 212.A N ARG 256.A O no hydrogen 2.866 N/A TRP 213.A NE1 ALA 241.A O no hydrogen 2.866 N/A GLN 214.A N THR 254.A O no hydrogen 3.039 N/A ASN 216.A ND2 ASN 252.A OD1 no hydrogen 2.809 N/A GLU 225.A N SER 242.A O no hydrogen 2.813 N/A VAL 227.A N TRP 240.A O no hydrogen 3.416 N/A ARG 230.A N GLN 238.A O no hydrogen 2.934 N/A ARG 230.A NE GLN 238.A OE1 no hydrogen 2.935 N/A ARG 230.A NH2 GLN 238.A OE1 no hydrogen 3.265 N/A ALA 232.A N THR 236.A O no hydrogen 2.745 N/A THR 236.A N ASP 234.A OD1 no hydrogen 2.959 N/A THR 236.A OG1 ASP 234.A OD1 no hydrogen 2.913 N/A PHE 237.A N PHE 204.A O no hydrogen 2.948 N/A GLN 238.A N ARG 230.A O no hydrogen 2.744 N/A LYS 239.A N ALA 201.A O no hydrogen 3.053 N/A LYS 239.A NZ VAL 227.A O no hydrogen 2.410 N/A LYS 239.A NZ THR 229.A OG1 no hydrogen 3.347 N/A ALA 241.A N CYS 199.A O no hydrogen 3.016 N/A SER 242.A N GLU 225.A O no hydrogen 2.564 N/A SER 242.A OG GLU 225.A O no hydrogen 3.478 N/A VAL 243.A N LEU 197.A O no hydrogen 3.147 N/A VAL 245.A N VAL 195.A O no hydrogen 3.010 N/A GLY 248.A N GLU 250.A OE1 no hydrogen 3.016 N/A LYS 249.A N PRO 246.A O no hydrogen 3.169 N/A TYR 253.A N GLU 250.A O no hydrogen 2.864 N/A THR 254.A N GLN 214.A O no hydrogen 3.211 N/A CYS 255.A N LEU 268.A O no hydrogen 2.876 N/A CYS 255.A SG THR 212.A O no hydrogen 3.990 N/A ARG 256.A N THR 212.A O no hydrogen 2.593 N/A VAL 257.A N LEU 266.A O no hydrogen 2.892 N/A TYR 258.A N THR 210.A O no hydrogen 2.710 N/A HIS 259.A NE2 PRO 206.A O no hydrogen 2.769 N/A GLY 261.A N HIS 259.A ND1 no hydrogen 3.138 N/A LEU 262.A N HIS 259.A O no hydrogen 3.117 N/A LEU 266.A N VAL 257.A O no hydrogen 3.145 N/A LEU 268.A N CYS 255.A O no hydrogen 2.888 N/A