Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5em5_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 4.A ND2 TYR 64.A OH no hydrogen 3.217 N/A ASN 4.A ND2 SER 68.A OG no hydrogen 2.811 N/A ALA 6.A N ASN 4.A OD1 no hydrogen 3.281 N/A LEU 11.A N ILE 80.A O no hydrogen 2.766 N/A GLU 15.A N LYS 12.A O no hydrogen 3.003 N/A PHE 16.A N GLU 13.A O no hydrogen 3.475 N/A LYS 17.A N LEU 34.A O no hydrogen 2.877 N/A LYS 17.A NZ THR 14.A O no hydrogen 3.038 N/A LYS 18.A NZ GLN 87.A OE1 no hydrogen 2.868 N/A ILE 19.A N LYS 32.A O no hydrogen 2.791 N/A LYS 20.A N LYS 32.A O no hydrogen 3.458 N/A LEU 22.A N VAL 30.A O no hydrogen 2.761 N/A GLY 23.A N VAL 30.A O no hydrogen 3.384 N/A SER 24.A OG GLY 28.A O no hydrogen 2.744 N/A GLY 25.A N GLY 28.A O no hydrogen 3.050 N/A PHE 27.A N GLY 25.A O no hydrogen 2.778 N/A VAL 30.A N GLY 23.A O no hydrogen 2.813 N/A TYR 31.A N ILE 48.A O no hydrogen 2.801 N/A TYR 31.A OH GLU 50.A OE1 no hydrogen 2.843 N/A LYS 32.A N LYS 20.A O no hydrogen 2.795 N/A LYS 32.A NZ GLU 283.A OE2 no hydrogen 3.207 N/A GLY 33.A N VAL 46.A O no hydrogen 2.780 N/A LEU 34.A N LYS 17.A O no hydrogen 2.980 N/A TRP 35.A N ILE 44.A O no hydrogen 2.853 N/A ILE 36.A N GLU 15.A O no hydrogen 2.768 N/A GLU 38.A N GLU 15.A OE1 no hydrogen 3.125 N/A GLU 40.A N PRO 37.A O no hydrogen 3.431 N/A LYS 43.A N ASP 288.A O no hydrogen 3.046 N/A ILE 44.A N TRP 35.A O no hydrogen 2.913 N/A VAL 46.A N GLY 33.A O no hydrogen 2.804 N/A ALA 47.A N MET 90.A O no hydrogen 2.789 N/A ILE 48.A N TYR 31.A O no hydrogen 2.901 N/A LYS 49.A N LEU 88.A O no hydrogen 2.999 N/A LYS 49.A NZ GLU 62.A OE1 no hydrogen 3.101 N/A LYS 49.A NZ GLU 62.A OE2 no hydrogen 3.222 N/A GLU 50.A N THR 29.A O no hydrogen 3.247 N/A ASN 56.A N SER 52.A O no hydrogen 3.250 N/A LYS 57.A N PRO 53.A O no hydrogen 3.144 N/A LYS 57.A NZ ASP 61.A OD1 no hydrogen 3.538 N/A LYS 57.A NZ ASP 61.A OD2 no hydrogen 2.820 N/A GLU 58.A N LYS 54.A O no hydrogen 3.124 N/A ILE 59.A N ALA 55.A O no hydrogen 3.056 N/A LEU 60.A N ASN 56.A O no hydrogen 3.221 N/A ASP 61.A N LYS 57.A O no hydrogen 3.091 N/A GLU 62.A N GLU 58.A O no hydrogen 3.249 N/A ALA 63.A N ILE 59.A O no hydrogen 3.038 N/A TYR 64.A N LEU 60.A O no hydrogen 2.972 N/A VAL 65.A N ASP 61.A O no hydrogen 3.407 N/A MET 66.A N GLU 62.A O no hydrogen 3.073 N/A ALA 67.A N ALA 63.A O no hydrogen 2.896 N/A SER 68.A N VAL 65.A O no hydrogen 3.154 N/A SER 68.A OG TYR 64.A O no hydrogen 2.731 N/A ASP 70.A N TYR 127.A OH no hydrogen 2.803 N/A HIS 73.A N ASN 71.A OD1 no hydrogen 2.910 N/A HIS 73.A ND1 VAL 151.A O no hydrogen 3.370 N/A VAL 74.A N ASN 71.A O no hydrogen 3.220 N/A CYS 75.A N ILE 153.A O no hydrogen 2.777 N/A CYS 75.A SG LYS 152.A O no hydrogen 4.035 N/A ARG 76.A NE VAL 69.A O no hydrogen 3.205 N/A LEU 77.A N MET 66.A O no hydrogen 3.383 N/A LEU 78.A N ILE 89.A O no hydrogen 2.814 N/A GLY 79.A N ILE 89.A O no hydrogen 3.161 N/A ILE 80.A N ARG 9.A O no hydrogen 2.877 N/A CYS 81.A N GLN 87.A O no hydrogen 2.819 N/A CYS 81.A SG LEU 11.A O no hydrogen 3.366 N/A THR 83.A OG1 THR 85.A O no hydrogen 2.762 N/A GLN 87.A N CYS 81.A O no hydrogen 2.969 N/A GLN 87.A NE2 THR 83.A OG1 no hydrogen 3.298 N/A LEU 88.A N LYS 49.A O no hydrogen 2.987 N/A ILE 89.A N GLY 79.A O no hydrogen 2.816 N/A MET 90.A N ALA 47.A O no hydrogen 2.932 N/A GLN 91.A NE2 ASP 291.A OD1 no hydrogen 3.316 N/A GLN 91.A NE2 ASP 293.A OD2 no hydrogen 3.136 N/A LEU 92.A N PRO 45.A O no hydrogen 3.175 N/A PHE 95.A N VAL 145.A O no hydrogen 3.214 N/A GLY 96.A N MET 93.A O no hydrogen 3.306 N/A CYS 97.A SG ASP 100.A OD1 no hydrogen 3.396 N/A LEU 98.A N VAL 143.A O no hydrogen 2.776 N/A LEU 99.A N ALA 140.A O no hydrogen 3.183 N/A TYR 101.A N CYS 97.A O no hydrogen 3.113 N/A VAL 102.A N LEU 98.A O no hydrogen 2.996 N/A ARG 103.A N LEU 99.A O no hydrogen 3.429 N/A ARG 103.A NE GLY 195.A O no hydrogen 2.744 N/A ARG 103.A NH2 GLY 195.A O no hydrogen 3.171 N/A GLU 104.A N ASP 100.A O no hydrogen 3.007 N/A HIS 105.A N TYR 101.A O no hydrogen 2.971 N/A HIS 105.A ND1 TYR 101.A O no hydrogen 2.917 N/A LYS 106.A NZ ARG 103.A O no hydrogen 3.329 N/A ASN 108.A N HIS 105.A O no hydrogen 2.794 N/A SER 111.A OG ASP 268.A OD2 no hydrogen 2.763 N/A GLN 112.A NE2 GLN 112.A O no hydrogen 3.652 N/A GLN 112.A NE2 ASN 116.A OD1 no hydrogen 3.330 N/A GLN 112.A NE2 ALA 256.A O no hydrogen 2.814 N/A TYR 113.A OH GLN 149.A OE1 no hydrogen 3.125 N/A LEU 114.A N GLY 110.A O no hydrogen 3.380 N/A LEU 115.A N SER 111.A O no hydrogen 3.093 N/A ASN 116.A N GLN 112.A O no hydrogen 2.998 N/A TRP 117.A N TYR 113.A O no hydrogen 2.916 N/A TRP 117.A NE1 PRO 148.A O no hydrogen 2.757 N/A CYS 118.A N LEU 114.A O no hydrogen 3.226 N/A CYS 118.A SG LEU 114.A O no hydrogen 3.247 N/A VAL 119.A N LEU 115.A O no hydrogen 3.179 N/A GLN 120.A N ASN 116.A O no hydrogen 2.937 N/A GLN 120.A NE2 GLN 149.A O no hydrogen 2.948 N/A ILE 121.A N TRP 117.A O no hydrogen 2.835 N/A ALA 122.A N CYS 118.A O no hydrogen 3.097 N/A LYS 123.A N VAL 119.A O no hydrogen 2.873 N/A GLY 124.A N GLN 120.A O no hydrogen 3.082 N/A MET 125.A N ILE 121.A O no hydrogen 3.027 N/A ASN 126.A N ALA 122.A O no hydrogen 2.841 N/A TYR 127.A N LYS 123.A O no hydrogen 3.066 N/A LEU 128.A N GLY 124.A O no hydrogen 3.012 N/A GLU 129.A N MET 125.A O no hydrogen 2.939 N/A ASP 130.A N ASN 126.A O no hydrogen 2.962 N/A ARG 131.A N TYR 127.A O no hydrogen 3.009 N/A ARG 131.A NH1 SER 68.A O no hydrogen 2.777 N/A ARG 131.A NH1 TYR 127.A OH no hydrogen 3.359 N/A ARG 132.A N GLU 129.A O no hydrogen 2.941 N/A LEU 133.A N LEU 128.A O no hydrogen 2.758 N/A HIS 135.A N ASP 180.A OD1 no hydrogen 2.968 N/A HIS 135.A NE2 THR 154.A O no hydrogen 2.799 N/A ARG 136.A N ASP 180.A OD2 no hydrogen 3.044 N/A ASP 137.A N HIS 135.A ND1 no hydrogen 3.063 N/A ALA 140.A N GLU 190.A OE2 no hydrogen 2.881 N/A ARG 141.A NH1 ASP 137.A OD1 no hydrogen 3.292 N/A ARG 141.A NH1 ASP 137.A OD2 no hydrogen 3.053 N/A ARG 141.A NH2 ASP 137.A OD2 no hydrogen 3.400 N/A ASN 142.A N ALA 139.A O no hydrogen 2.905 N/A ASN 142.A ND2 ASP 137.A O no hydrogen 2.753 N/A ASN 142.A ND2 ASP 137.A OD1 no hydrogen 3.235 N/A VAL 143.A N ALA 140.A O no hydrogen 3.393 N/A LEU 144.A N LYS 152.A O no hydrogen 2.763 N/A VAL 145.A N GLY 96.A O no hydrogen 2.761 N/A LYS 146.A N HIS 150.A O no hydrogen 2.982 N/A LYS 146.A NZ ASP 291.A OD2 no hydrogen 3.430 N/A LYS 146.A NZ ASP 293.A OD2 no hydrogen 2.796 N/A THR 147.A N HIS 150.A O no hydrogen 3.280 N/A GLN 149.A NE2 PRO 274.A O no hydrogen 3.696 N/A HIS 150.A N THR 147.A O no hydrogen 2.807 N/A HIS 150.A NE2 PRO 72.A O no hydrogen 2.800 N/A VAL 151.A N GLN 120.A OE1 no hydrogen 2.748 N/A LYS 152.A N LEU 144.A O no hydrogen 2.906 N/A LYS 152.A NZ GLN 91.A OE1 no hydrogen 2.942 N/A LYS 152.A NZ ASP 293.A OD1 no hydrogen 2.895 N/A LYS 152.A NZ ASP 293.A OD2 no hydrogen 3.103 N/A ILE 153.A N HIS 73.A O no hydrogen 3.019 N/A THR 154.A N ASN 142.A O no hydrogen 2.882 N/A ASP 155.A N THR 154.A OG1 no hydrogen 2.886 N/A ALA 159.A N PHE 156.A O no hydrogen 3.344 N/A ILE 162.A N VAL 160.A O no hydrogen 3.001 N/A LYS 163.A NZ TYR 199.A O no hydrogen 2.942 N/A LYS 163.A NZ ILE 202.A O no hydrogen 2.816 N/A TRP 164.A N PRO 161.A O no hydrogen 3.211 N/A TRP 164.A NE1 GLU 190.A OE2 no hydrogen 2.766 N/A MET 165.A N ILE 162.A O no hydrogen 2.964 N/A GLU 168.A N GLU 168.A OE2 no hydrogen 2.805 N/A SER 169.A N ALA 166.A O no hydrogen 3.163 N/A SER 169.A OG ILE 174.A O no hydrogen 2.805 N/A ILE 170.A N ALA 166.A O no hydrogen 3.263 N/A LEU 171.A N LEU 167.A O no hydrogen 3.116 N/A HIS 172.A N GLU 168.A O no hydrogen 2.883 N/A ILE 174.A N GLU 168.A O no hydrogen 3.135 N/A THR 176.A N SER 179.A OG no hydrogen 2.775 N/A GLN 178.A NE2 ALA 239.A O no hydrogen 2.889 N/A GLN 178.A NE2 ARG 242.A O no hydrogen 3.156 N/A GLN 178.A NE2 PRO 243.A O no hydrogen 3.484 N/A SER 179.A OG THR 176.A O no hydrogen 2.714 N/A ASP 180.A N THR 176.A O no hydrogen 3.311 N/A SER 183.A N SER 179.A O no hydrogen 3.472 N/A SER 183.A OG TRP 164.A O no hydrogen 2.720 N/A SER 183.A OG SER 179.A O no hydrogen 3.478 N/A TYR 184.A N ASP 180.A O no hydrogen 2.906 N/A TYR 184.A OH CYS 118.A O no hydrogen 2.648 N/A GLY 185.A N VAL 181.A O no hydrogen 3.010 N/A VAL 186.A N TRP 182.A O no hydrogen 3.147 N/A THR 187.A N SER 183.A O no hydrogen 2.905 N/A THR 187.A OG1 SER 183.A O no hydrogen 2.703 N/A VAL 188.A N TYR 184.A O no hydrogen 2.879 N/A TRP 189.A N GLY 185.A O no hydrogen 3.130 N/A TRP 189.A NE1 PRO 218.A O no hydrogen 2.821 N/A GLU 190.A N VAL 186.A O no hydrogen 2.926 N/A LEU 191.A N THR 187.A O no hydrogen 3.076 N/A MET 192.A N VAL 188.A O no hydrogen 2.875 N/A THR 193.A N TRP 189.A O no hydrogen 3.013 N/A THR 193.A OG1 TRP 189.A O no hydrogen 2.735 N/A THR 193.A OG1 GLU 190.A O no hydrogen 3.201 N/A PHE 194.A N LEU 191.A O no hydrogen 3.003 N/A GLY 195.A N GLU 190.A O no hydrogen 2.733 N/A SER 196.A N THR 193.A OG1 no hydrogen 3.408 N/A SER 196.A OG THR 193.A O no hydrogen 3.183 N/A ILE 202.A N TYR 199.A O no hydrogen 3.202 N/A GLU 206.A N PRO 203.A O no hydrogen 3.359 N/A ILE 210.A N GLU 206.A O no hydrogen 2.980 N/A LEU 211.A N ILE 207.A O no hydrogen 2.940 N/A GLU 212.A N SER 208.A O no hydrogen 3.122 N/A LYS 213.A N SER 209.A O no hydrogen 2.892 N/A GLY 214.A N ILE 210.A O no hydrogen 3.299 N/A GLY 214.A N LEU 211.A O no hydrogen 3.294 N/A GLU 215.A N ILE 210.A O no hydrogen 3.106 N/A ARG 216.A NE TRP 235.A O no hydrogen 2.839 N/A ARG 216.A NH1 LEU 211.A O no hydrogen 2.948 N/A ARG 216.A NH1 GLU 215.A O no hydrogen 3.161 N/A ARG 216.A NH2 TRP 235.A O no hydrogen 2.790 N/A GLN 219.A NE2 CYS 223.A O no hydrogen 3.162 N/A CYS 223.A N PRO 220.A O no hydrogen 2.856 N/A THR 224.A N TYR 262.A O no hydrogen 3.407 N/A THR 224.A OG1 TYR 262.A O no hydrogen 2.707 N/A VAL 227.A N THR 224.A O no hydrogen 3.106 N/A TYR 228.A N THR 224.A O no hydrogen 3.130 N/A TYR 228.A OH LEU 217.A O no hydrogen 2.730 N/A MET 229.A N ILE 225.A O no hydrogen 2.815 N/A ILE 230.A N VAL 227.A O no hydrogen 3.110 N/A MET 231.A N VAL 227.A O no hydrogen 3.352 N/A VAL 232.A N TYR 228.A O no hydrogen 2.911 N/A LYS 233.A N MET 229.A O no hydrogen 2.899 N/A CYS 234.A N ILE 230.A O no hydrogen 3.086 N/A CYS 234.A N MET 231.A O no hydrogen 3.122 N/A CYS 234.A SG ILE 230.A O no hydrogen 3.324 N/A TRP 235.A N VAL 232.A O no hydrogen 2.943 N/A SER 241.A N ASP 238.A O no hydrogen 3.234 N/A SER 241.A OG ASP 238.A OD2 no hydrogen 2.727 N/A ARG 242.A N ALA 239.A O no hydrogen 3.259 N/A ARG 242.A NE MET 236.A O no hydrogen 2.867 N/A ARG 242.A NH1 GLU 168.A OE2 no hydrogen 2.733 N/A ARG 242.A NH1 MET 236.A O no hydrogen 2.815 N/A ARG 242.A NH2 GLU 168.A OE1 no hydrogen 3.194 N/A ARG 242.A NH2 GLU 168.A OE2 no hydrogen 3.543 N/A ARG 242.A NH2 GLN 178.A O no hydrogen 3.058 N/A LYS 244.A N GLU 247.A OE1 no hydrogen 2.939 N/A LYS 244.A NZ ASP 240.A O no hydrogen 3.418 N/A LYS 244.A NZ ARG 242.A O no hydrogen 3.497 N/A GLU 247.A N LYS 244.A O no hydrogen 2.980 N/A LEU 248.A N LYS 244.A O no hydrogen 3.091 N/A ILE 249.A N PHE 245.A O no hydrogen 3.079 N/A ILE 250.A N ARG 246.A O no hydrogen 3.364 N/A GLU 251.A N GLU 247.A O no hydrogen 2.907 N/A PHE 252.A N LEU 248.A O no hydrogen 3.029 N/A SER 253.A N ILE 249.A O no hydrogen 2.874 N/A SER 253.A OG ILE 249.A O no hydrogen 2.713 N/A LYS 254.A N ILE 250.A O no hydrogen 2.939 N/A LYS 254.A NZ GLU 251.A OE1 no hydrogen 3.198 N/A MET 255.A N GLU 251.A O no hydrogen 3.284 N/A ALA 256.A N PHE 252.A O no hydrogen 2.816 N/A ARG 257.A N LYS 254.A O no hydrogen 3.337 N/A ASP 258.A N MET 255.A O no hydrogen 3.187 N/A ARG 261.A N ASP 258.A O no hydrogen 3.286 N/A TYR 262.A N PRO 259.A O no hydrogen 3.181 N/A LEU 263.A N PRO 259.A O no hydrogen 3.082 N/A VAL 264.A N ILE 222.A O no hydrogen 2.907 N/A ASP 268.A N ILE 265.A O no hydrogen 3.406 N/A HIS 272.A ND1 LEU 273.A O no hydrogen 3.179 N/A SER 275.A OG GLN 149.A OE1 no hydrogen 2.739 N/A SER 275.A OG LEU 273.A O no hydrogen 3.495 N/A THR 277.A OG1 ASP 278.A OD2 no hydrogen 3.383 N/A ASP 278.A N SER 275.A O no hydrogen 2.828 N/A VAL 290.A N LYS 43.A O no hydrogen 3.044 N/A ASP 293.A N ASP 291.A OD2 no hydrogen 2.961 N/A GLU 294.A N ASP 291.A O no hydrogen 3.074 N/A TYR 295.A N ALA 292.A O no hydrogen 3.396 N/A ILE 297.A N TYR 295.A O no hydrogen 2.734 N/A