Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5f9e_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 3.A N ASP 6.A OD1 no hydrogen 2.882 N/A GLU 5.A N GLU 5.A OE1 no hydrogen 2.701 N/A ASP 6.A N LYS 3.A O no hydrogen 2.959 N/A PHE 7.A N ILE 4.A O no hydrogen 3.051 N/A GLU 8.A N GLU 25.A O no hydrogen 2.941 N/A HIS 10.A N LEU 23.A O no hydrogen 2.851 N/A HIS 10.A NE2 GLU 25.A OE1 no hydrogen 2.922 N/A LYS 11.A N LEU 23.A O no hydrogen 3.489 N/A LEU 13.A N VAL 21.A O no hydrogen 2.828 N/A GLY 14.A N VAL 21.A O no hydrogen 3.422 N/A LYS 15.A NZ GLU 298.A OE1 no hydrogen 3.539 N/A LYS 15.A NZ GLU 298.A OE2 no hydrogen 2.740 N/A GLY 16.A N GLY 19.A O no hydrogen 3.118 N/A GLY 19.A N GLY 16.A O no hydrogen 3.185 N/A LYS 20.A N ALA 37.A O no hydrogen 3.241 N/A LYS 20.A NZ ARG 301.A O no hydrogen 2.899 N/A VAL 21.A N GLY 14.A O no hydrogen 2.948 N/A PHE 22.A N ILE 35.A O no hydrogen 2.840 N/A LEU 23.A N LYS 11.A O no hydrogen 2.935 N/A ALA 24.A N PHE 33.A O no hydrogen 2.861 N/A GLU 25.A N GLU 8.A O no hydrogen 2.916 N/A PHE 26.A N GLN 31.A O no hydrogen 2.992 N/A LYS 27.A N ASP 6.A O no hydrogen 2.705 N/A LYS 27.A NZ HIS 333.A O no hydrogen 3.442 N/A THR 29.A OG1 PHE 26.A O no hydrogen 2.929 N/A GLN 31.A N THR 29.A OG1 no hydrogen 3.198 N/A PHE 33.A N ALA 24.A O no hydrogen 2.802 N/A ALA 34.A N MET 85.A O no hydrogen 2.864 N/A ILE 35.A N PHE 22.A O no hydrogen 2.927 N/A LYS 36.A N PHE 83.A O no hydrogen 2.919 N/A LYS 36.A NZ GLU 55.A OE1 no hydrogen 2.923 N/A LYS 36.A NZ GLU 55.A OE2 no hydrogen 2.717 N/A ALA 37.A N LYS 20.A O no hydrogen 2.768 N/A LEU 38.A N LEU 81.A O no hydrogen 2.887 N/A LYS 39.A NZ GLU 79.A OE2 no hydrogen 2.784 N/A LYS 39.A NZ ASN 80.A OD1 no hydrogen 2.889 N/A LYS 40.A N GLU 79.A O no hydrogen 2.796 N/A LYS 40.A NZ GLN 76.A OE1 no hydrogen 2.738 N/A LYS 40.A NZ THR 77.A O no hydrogen 2.594 N/A LYS 40.A NZ GLN 314.A OE1 no hydrogen 3.074 N/A VAL 43.A N LYS 39.A O no hydrogen 3.022 N/A LEU 44.A N LYS 40.A O no hydrogen 2.909 N/A MET 45.A N ASP 41.A O no hydrogen 3.094 N/A ASP 46.A N VAL 42.A O no hydrogen 2.946 N/A ASP 47.A N LEU 44.A O no hydrogen 3.051 N/A ASP 48.A N VAL 43.A O no hydrogen 2.913 N/A THR 52.A N ASP 48.A O no hydrogen 3.028 N/A THR 52.A OG1 ASP 48.A O no hydrogen 2.925 N/A MET 53.A N VAL 49.A O no hydrogen 3.221 N/A VAL 54.A N GLU 50.A O no hydrogen 2.780 N/A GLU 55.A N CYS 51.A O no hydrogen 2.911 N/A LYS 56.A N THR 52.A O no hydrogen 3.120 N/A LYS 56.A NZ ASN 319.A O no hydrogen 3.040 N/A ARG 57.A N MET 53.A O no hydrogen 2.964 N/A ARG 57.A NE GLU 155.A OE1 no hydrogen 3.338 N/A ARG 57.A NE GLU 155.A OE2 no hydrogen 2.747 N/A ARG 57.A NH2 GLU 50.A OE2 no hydrogen 2.965 N/A ARG 57.A NH2 GLU 155.A OE1 no hydrogen 2.781 N/A VAL 58.A N VAL 54.A O no hydrogen 2.798 N/A LEU 59.A N GLU 55.A O no hydrogen 2.958 N/A SER 60.A N LYS 56.A O no hydrogen 3.099 N/A SER 60.A OG LYS 56.A O no hydrogen 3.119 N/A ALA 62.A N LEU 59.A O no hydrogen 3.009 N/A GLU 64.A N LEU 61.A O no hydrogen 3.486 N/A HIS 65.A N ALA 62.A O no hydrogen 3.054 N/A PHE 67.A N HIS 65.A ND1 no hydrogen 3.132 N/A THR 69.A N ILE 147.A O no hydrogen 3.017 N/A THR 69.A OG1 ILE 147.A O no hydrogen 3.487 N/A HIS 70.A N GLU 86.A OE1 no hydrogen 3.013 N/A HIS 70.A NE2 HIS 65.A O no hydrogen 2.750 N/A PHE 72.A N VAL 84.A O no hydrogen 2.836 N/A CYS 73.A N VAL 84.A O no hydrogen 3.369 N/A THR 74.A N PHE 321.A O no hydrogen 2.831 N/A PHE 75.A N PHE 82.A O no hydrogen 3.027 N/A GLN 76.A NE2 PHE 317.A O no hydrogen 2.931 N/A THR 77.A N ASN 80.A O no hydrogen 2.985 N/A ASN 80.A N THR 77.A OG1 no hydrogen 3.091 N/A ASN 80.A ND2 THR 77.A OG1 no hydrogen 3.308 N/A LEU 81.A N LEU 38.A O no hydrogen 2.858 N/A PHE 82.A N PHE 75.A O no hydrogen 2.920 N/A PHE 83.A N LYS 36.A O no hydrogen 2.978 N/A VAL 84.A N CYS 73.A O no hydrogen 2.805 N/A MET 85.A N ALA 34.A O no hydrogen 2.741 N/A GLU 86.A N HIS 70.A O no hydrogen 2.991 N/A TYR 87.A OH ASP 287.A O no hydrogen 2.752 N/A ASN 89.A ND2 SER 284.A O no hydrogen 3.074 N/A ASN 89.A ND2 ASP 287.A O no hydrogen 3.347 N/A GLY 90.A N LEU 139.A O no hydrogen 3.028 N/A LEU 93.A N ILE 137.A O no hydrogen 2.951 N/A TYR 95.A N ASP 92.A OD2 no hydrogen 2.874 N/A HIS 96.A N ASP 92.A O no hydrogen 2.957 N/A HIS 96.A NE2 GLY 90.A O no hydrogen 2.651 N/A ILE 97.A N LEU 93.A O no hydrogen 2.773 N/A GLN 98.A N MET 94.A O no hydrogen 3.289 N/A GLN 98.A NE2 MET 94.A O no hydrogen 3.076 N/A SER 99.A OG HIS 96.A O no hydrogen 3.511 N/A CYS 100.A SG HIS 96.A O no hydrogen 3.561 N/A CYS 100.A SG LYS 102.A O no hydrogen 3.489 N/A HIS 101.A N ILE 97.A O no hydrogen 2.750 N/A LYS 102.A N CYS 100.A O no hydrogen 2.826 N/A LYS 102.A NZ HIS 101.A ND1 no hydrogen 3.218 N/A PHE 103.A N MET 199.A O no hydrogen 2.836 N/A SER 106.A OG.A ASP 104.A OD1 no hydrogen 2.916 N/A ARG 107.A N ASP 104.A OD1 no hydrogen 3.111 N/A ARG 107.A NE TYR 111.A OH no hydrogen 2.978 N/A ARG 107.A NH2 TYR 111.A OH no hydrogen 3.487 N/A ALA 108.A N ASP 104.A O no hydrogen 2.929 N/A THR 109.A N LEU 105.A O no hydrogen 2.882 N/A THR 109.A OG1 LEU 105.A O no hydrogen 2.803 N/A PHE 110.A N SER 106.A O no hydrogen 2.975 N/A TYR 111.A N ARG 107.A O no hydrogen 2.997 N/A ALA 112.A N ALA 108.A O no hydrogen 2.814 N/A ALA 113.A N THR 109.A O no hydrogen 3.001 N/A GLU 114.A N PHE 110.A O no hydrogen 3.073 N/A ILE 115.A N TYR 111.A O no hydrogen 2.905 N/A ILE 116.A N ALA 112.A O no hydrogen 2.906 N/A LEU 117.A N ALA 113.A O no hydrogen 3.171 N/A GLY 118.A N GLU 114.A O no hydrogen 3.062 N/A LEU 119.A N ILE 115.A O no hydrogen 2.866 N/A GLN 120.A N ILE 116.A O no hydrogen 2.840 N/A PHE 121.A N LEU 117.A O no hydrogen 3.053 N/A LEU 122.A N GLY 118.A O no hydrogen 3.097 N/A HIS 123.A N LEU 119.A O no hydrogen 2.843 N/A HIS 123.A NE2 ASP 188.A OD2 no hydrogen 2.781 N/A SER 124.A N GLN 120.A O no hydrogen 2.938 N/A SER 124.A OG PHE 121.A O no hydrogen 2.759 N/A LYS 125.A N PHE 121.A O no hydrogen 3.285 N/A LYS 125.A N LEU 122.A O no hydrogen 3.083 N/A GLY 126.A N HIS 123.A O no hydrogen 2.901 N/A ILE 127.A N LEU 122.A O no hydrogen 3.048 N/A VAL 128.A N LYS 154.A O no hydrogen 3.060 N/A TYR 129.A N ASP 188.A OD2 no hydrogen 2.846 N/A TYR 129.A OH ALA 148.A O no hydrogen 2.580 N/A TYR 129.A OH ASP 149.A O no hydrogen 3.188 N/A ARG 130.A N ASP 188.A OD1 no hydrogen 2.707 N/A ARG 130.A NE MET 152.A O no hydrogen 2.862 N/A ARG 130.A NH1 GLU 165.A OE1 no hydrogen 2.872 N/A ARG 130.A NH1 TYR 183.A OH no hydrogen 2.923 N/A ARG 130.A NH2 MET 152.A O no hydrogen 2.948 N/A LYS 133.A NZ THR 169.A OG1 no hydrogen 3.006 N/A LEU 134.A N TYR 172.A OH no hydrogen 3.193 N/A ASN 136.A N LYS 133.A O no hydrogen 3.083 N/A ASN 136.A ND2 TYR 129.A OH no hydrogen 3.112 N/A ASN 136.A ND2 ASP 131.A O no hydrogen 3.156 N/A ASN 136.A ND2 ASP 131.A OD2 no hydrogen 3.444 N/A ILE 137.A N LEU 134.A O no hydrogen 3.239 N/A LEU 138.A N LYS 146.A O no hydrogen 2.824 N/A LEU 139.A N GLY 91.A O no hydrogen 2.886 N/A ASP 140.A N HIS 144.A O no hydrogen 2.862 N/A LYS 141.A NZ ASP 142.A OD2 no hydrogen 3.560 N/A ASP 142.A N ASP 140.A OD1 no hydrogen 2.831 N/A GLY 143.A N ASP 140.A O no hydrogen 3.105 N/A HIS 144.A N ASP 140.A OD1 no hydrogen 2.932 N/A HIS 144.A ND1 GLU 114.A OE1 no hydrogen 2.750 N/A ILE 145.A N GLU 114.A OE2 no hydrogen 2.901 N/A LYS 146.A N LEU 138.A O no hydrogen 2.732 N/A LYS 146.A NZ PRO 66.A O no hydrogen 3.057 N/A LYS 146.A NZ LEU 68.A O no hydrogen 3.150 N/A LYS 146.A NZ GLU 86.A OE1 no hydrogen 3.080 N/A LYS 146.A NZ GLU 86.A OE2 no hydrogen 3.491 N/A ILE 147.A N PHE 67.A O no hydrogen 2.892 N/A ALA 148.A N ASN 136.A O no hydrogen 2.883 N/A GLY 151.A N ASP 149.A OD1 no hydrogen 3.195 N/A CYS 153.A N PHE 150.A O no hydrogen 3.212 N/A CYS 153.A SG PHE 150.A O no hydrogen 3.456 N/A LYS 154.A N VAL 128.A O no hydrogen 2.852 N/A LYS 154.A NZ THR 163.A OG1 no hydrogen 3.407 N/A LYS 154.A NZ GLU 165.A OE2 no hydrogen 2.897 N/A MET 157.A N GLY 126.A O no hydrogen 2.745 N/A THR 163.A N TYR 183.A O no hydrogen 2.984 N/A THR 163.A OG1 GLU 165.A OE1 no hydrogen 2.627 N/A GLU 165.A N GLU 165.A OE1 no hydrogen 2.864 N/A CYS 167.A SG GLU 165.A O no hydrogen 3.937 N/A THR 169.A OG1 ASP 131.A OD1 no hydrogen 2.797 N/A TYR 172.A N THR 169.A O no hydrogen 2.878 N/A TYR 172.A OH GLU 198.A OE1 no hydrogen 2.451 N/A ILE 173.A N PRO 170.A O no hydrogen 3.494 N/A GLU 176.A N GLU 176.A OE1 no hydrogen 2.704 N/A ILE 177.A N ALA 174.A O no hydrogen 3.033 N/A LEU 178.A N ALA 174.A O no hydrogen 3.170 N/A LEU 179.A N PRO 175.A O no hydrogen 2.959 N/A GLY 180.A N ILE 177.A O no hydrogen 2.887 N/A GLN 181.A N GLU 176.A O no hydrogen 2.978 N/A GLN 181.A NE2 LEU 179.A O no hydrogen 3.179 N/A TYR 183.A N THR 163.A O no hydrogen 2.826 N/A TYR 183.A OH GLU 165.A O no hydrogen 2.578 N/A SER 186.A N ASN 184.A OD1 no hydrogen 3.050 N/A SER 186.A OG GLU 176.A OE2 no hydrogen 2.728 N/A SER 186.A OG ASN 184.A OD1 no hydrogen 3.416 N/A VAL 187.A N ASN 184.A O no hydrogen 3.360 N/A ASP 188.A N HIS 185.A O no hydrogen 3.021 N/A TRP 190.A N SER 186.A O no hydrogen 3.322 N/A SER 191.A N VAL 187.A O no hydrogen 3.148 N/A SER 191.A OG TYR 172.A O no hydrogen 2.775 N/A SER 191.A OG VAL 187.A O no hydrogen 3.182 N/A PHE 192.A N ASP 188.A O no hydrogen 2.872 N/A GLY 193.A N TRP 189.A O no hydrogen 3.147 N/A VAL 194.A N TRP 190.A O no hydrogen 3.013 N/A LEU 195.A N SER 191.A O no hydrogen 2.872 N/A LEU 196.A N PHE 192.A O no hydrogen 2.877 N/A TYR 197.A N GLY 193.A O no hydrogen 2.934 N/A TYR 197.A OH PHE 224.A O no hydrogen 2.569 N/A GLU 198.A N VAL 194.A O no hydrogen 2.923 N/A MET 199.A N LEU 195.A O no hydrogen 2.941 N/A LEU 200.A N LEU 196.A O no hydrogen 2.969 N/A ILE 201.A N TYR 197.A O no hydrogen 2.827 N/A GLY 202.A N GLU 198.A O no hydrogen 2.797 N/A SER 204.A OG GLU 198.A OE2 no hydrogen 2.741 N/A HIS 207.A N SER 217.A OG no hydrogen 3.204 N/A GLN 209.A N GLU 213.A OE1 no hydrogen 2.874 N/A GLU 213.A N ASP 210.A OD1 no hydrogen 2.815 N/A LEU 214.A N ASP 210.A O no hydrogen 3.029 N/A PHE 215.A N GLU 211.A O no hydrogen 2.739 N/A HIS 216.A N GLU 212.A O no hydrogen 3.099 N/A SER 217.A N GLU 213.A O no hydrogen 2.911 N/A ILE 218.A N LEU 214.A O no hydrogen 2.930 N/A ARG 219.A N PHE 215.A O no hydrogen 2.946 N/A MET 220.A N SER 217.A O no hydrogen 3.185 N/A ASP 221.A N SER 217.A O no hydrogen 2.919 N/A LEU 229.A N PRO 226.A O no hydrogen 3.000 N/A GLU 232.A N GLU 230.A OE2 no hydrogen 2.975 N/A LYS 234.A N GLU 230.A O no hydrogen 3.022 N/A ASP 235.A N LYS 231.A O no hydrogen 2.924 N/A LEU 236.A N GLU 232.A O no hydrogen 3.061 N/A LEU 237.A N ALA 233.A O no hydrogen 3.088 N/A VAL 238.A N LYS 234.A O no hydrogen 2.821 N/A LYS 239.A N ASP 235.A O no hydrogen 3.097 N/A LYS 239.A NZ ASP 235.A OD1 no hydrogen 3.197 N/A LYS 239.A NZ ASP 235.A OD2 no hydrogen 2.737 N/A LEU 240.A N LEU 236.A O no hydrogen 3.002 N/A LEU 240.A N LEU 237.A O no hydrogen 3.062 N/A PHE 241.A N LEU 237.A O no hydrogen 2.911 N/A ARG 243.A NE ILE 218.A O no hydrogen 2.915 N/A ARG 243.A NH2 ILE 218.A O no hydrogen 2.845 N/A ARG 243.A NH2 ASP 221.A O no hydrogen 2.700 N/A GLU 246.A N GLU 244.A OE2 no hydrogen 2.950 N/A LYS 247.A N GLU 244.A O no hydrogen 2.953 N/A ARG 248.A N PRO 245.A O no hydrogen 3.179 N/A ARG 248.A NE VAL 242.A O no hydrogen 2.904 N/A ARG 248.A NH1 GLU 176.A OE1 no hydrogen 3.554 N/A ARG 248.A NH1 GLU 176.A OE2 no hydrogen 2.744 N/A ARG 248.A NH1 SER 186.A O no hydrogen 2.889 N/A ARG 248.A NH2 GLU 176.A OE1 no hydrogen 3.016 N/A ARG 248.A NH2 VAL 242.A O no hydrogen 2.924 N/A LEU 249.A N LYS 239.A O no hydrogen 3.160 N/A GLY 250.A N ARG 252.A O no hydrogen 3.178 N/A VAL 251.A N ARG 248.A O no hydrogen 2.926 N/A ARG 252.A N ARG 248.A O no hydrogen 2.826 N/A ARG 252.A NE.B LYS 247.A O no hydrogen 3.085 N/A ARG 256.A N ASP 254.A OD1 no hydrogen 3.061 N/A ARG 256.A NE GLN 120.A OE1 no hydrogen 2.782 N/A ARG 256.A NH2 GLN 120.A OE1 no hydrogen 2.808 N/A GLN 257.A N ASP 254.A O no hydrogen 2.945 N/A HIS 258.A N ILE 255.A O no hydrogen 3.049 N/A HIS 258.A NE2 ASP 235.A OD2 no hydrogen 2.744 N/A LEU 260.A N HIS 258.A ND1 no hydrogen 3.177 N/A PHE 261.A N HIS 258.A O no hydrogen 2.845 N/A ARG 262.A N PRO 259.A O no hydrogen 3.046 N/A ILE 264.A N PHE 261.A O no hydrogen 2.818 N/A TRP 266.A NE1 ARG 256.A O no hydrogen 3.149 N/A GLU 268.A N ASN 265.A OD1 no hydrogen 2.978 N/A LEU 269.A N ASN 265.A O no hydrogen 2.946 N/A GLU 270.A N TRP 266.A O no hydrogen 2.936 N/A ARG 271.A N GLU 267.A O no hydrogen 3.192 N/A ARG 271.A NE GLU 273.A OE1 no hydrogen 3.351 N/A ARG 271.A NE GLU 273.A OE2 no hydrogen 2.994 N/A ARG 271.A NH2 GLU 273.A OE1 no hydrogen 3.164 N/A LYS 272.A N LEU 269.A O no hydrogen 2.955 N/A GLU 273.A N GLU 268.A O no hydrogen 3.004 N/A LYS 283.A N ASP 287.A OD1 no hydrogen 3.122 N/A PHE 286.A N SER 284.A OG no hydrogen 3.312 N/A ASP 287.A N SER 284.A O no hydrogen 3.401 N/A SER 289.A N ASP 287.A OD2 no hydrogen 2.806 N/A SER 289.A OG ASP 287.A OD1 no hydrogen 3.391 N/A SER 289.A OG ASP 287.A OD2 no hydrogen 2.786 N/A ASN 290.A ND2 ASN 89.A O no hydrogen 3.096 N/A ASN 290.A ND2 LYS 281.A O no hydrogen 3.044 N/A LYS 293.A NZ TYR 95.A OH no hydrogen 2.824 N/A LYS 293.A NZ PHE 291.A O no hydrogen 2.747 N/A GLU 294.A N ASP 292.A OD1 no hydrogen 2.929 N/A PHE 295.A N ASP 292.A O no hydrogen 3.367 N/A ASN 297.A N LYS 293.A O no hydrogen 3.273 N/A GLU 298.A N PHE 295.A O no hydrogen 2.941 N/A ASP 305.A N ASP 41.A OD1 no hydrogen 2.828 N/A LEU 308.A N ASP 305.A OD1 no hydrogen 3.313 N/A ILE 309.A N ASP 305.A O no hydrogen 3.072 N/A ASN 310.A N ARG 306.A O no hydrogen 2.784 N/A SER 311.A N LEU 308.A O no hydrogen 3.312 N/A SER 311.A OG ALA 307.A O no hydrogen 2.808 N/A MET 312.A N LEU 308.A O no hydrogen 2.981 N/A GLN 314.A NE2 LYS 78.A O no hydrogen 2.834 N/A MET 316.A N ASP 313.A O no hydrogen 3.096 N/A PHE 317.A N GLN 314.A O no hydrogen 2.894 N/A ARG 318.A N ASN 315.A O no hydrogen 2.990 N/A PHE 320.A N PHE 317.A O no hydrogen 3.139 N/A ASN 323.A N PHE 72.A O no hydrogen 2.949 N/A MET 326.A N ASN 323.A OD1.A no hydrogen 2.723 N/A GLU 327.A N ASN 323.A O no hydrogen 2.978 N/A ARG 328.A N PRO 324.A O no hydrogen 2.928 N/A LEU 329.A N GLY 325.A O no hydrogen 3.147 N/A ILE 330.A N MET 326.A O no hydrogen 3.020 N/A SER 331.A N GLU 327.A O no hydrogen 3.003 N/A SER 331.A OG GLU 327.A O no hydrogen 2.799 N/A SER 331.A OG ARG 328.A O no hydrogen 3.153 N/A HIS 332.A N ARG 328.A O no hydrogen 2.961 N/A HIS 333.A N LEU 329.A O no hydrogen 3.353 N/A