Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5fa2_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LEU 6.A N GLN 57.A OE1 no hydrogen 3.213 N/A PHE 7.A N CYS 99.A O no hydrogen 3.108 N/A CYS 8.A SG ALA 27.A O no hydrogen 3.459 N/A ALA 9.A N HIS 97.A O no hydrogen 2.968 N/A SER 10.A N VAL 29.A O no hydrogen 3.023 N/A ALA 12.A N SER 10.A OG no hydrogen 2.962 N/A LYS 13.A N ASN 21.A OD1 no hydrogen 3.004 N/A GLU 16.A N LYS 13.A O no hydrogen 3.183 N/A GLU 18.A N GLU 16.A OE2 no hydrogen 3.164 N/A CYS 19.A N THR 90.A O no hydrogen 2.863 N/A CYS 19.A SG GLU 18.A OE2 no hydrogen 3.703 N/A CYS 19.A SG HIS 20.A ND1 no hydrogen 3.923 N/A CYS 19.A SG THR 90.A O no hydrogen 3.239 N/A HIS 20.A N GLU 18.A OE2 no hydrogen 2.908 N/A HIS 20.A ND1 GLU 18.A OE2 no hydrogen 2.694 N/A ASN 21.A N GLU 18.A OE1 no hydrogen 2.775 N/A ASN 21.A ND2 GLU 18.A OE1 no hydrogen 2.985 N/A VAL 22.A N GLU 18.A O no hydrogen 3.062 N/A TRP 23.A N CYS 19.A O no hydrogen 2.908 N/A TRP 23.A NE1 SER 64.A OG no hydrogen 2.955 N/A ALA 24.A N HIS 20.A O no hydrogen 2.978 N/A THR 25.A N ASN 21.A O no hydrogen 2.917 N/A THR 25.A OG1 ASN 21.A O no hydrogen 3.454 N/A THR 25.A OG1 VAL 22.A O no hydrogen 2.886 N/A ALA 27.A N TRP 23.A O no hydrogen 2.894 N/A CYS 28.A N ALA 24.A O no hydrogen 2.765 N/A VAL 29.A N CYS 8.A O no hydrogen 3.000 N/A THR 31.A N SER 10.A O no hydrogen 2.994 N/A THR 31.A OG1 ASP 11.A OD1 no hydrogen 2.542 N/A ASN 34.A N ASP 32.A OD1 no hydrogen 3.303 N/A VAL 38.A N THR 125.A O no hydrogen 3.054 N/A LEU 40.A N VAL 123.A O no hydrogen 3.060 N/A GLU 45.A N CYS 120.A O no hydrogen 3.072 N/A PHE 47.A N GLY 118.A O no hydrogen 2.909 N/A MET 49.A N GLY 116.A O no hydrogen 2.766 N/A TRP 50.A N ASN 48.A OD1 no hydrogen 2.882 N/A LYS 51.A N ASN 48.A O no hydrogen 3.108 N/A ASN 52.A ND2 TYR 330.A O no hydrogen 3.040 N/A MET 54.A N ASN 52.A OD1 no hydrogen 2.916 N/A VAL 55.A N ASN 52.A O no hydrogen 2.942 N/A GLN 57.A N ASP 53.A O no hydrogen 3.200 N/A GLN 57.A NE2 LEU 6.A O no hydrogen 3.573 N/A MET 58.A N MET 54.A O no hydrogen 3.061 N/A GLN 59.A N VAL 55.A O no hydrogen 2.990 N/A GLU 60.A N ASP 56.A O no hydrogen 3.074 N/A ASP 61.A N GLN 57.A O no hydrogen 2.995 N/A VAL 62.A N MET 58.A O no hydrogen 2.830 N/A ILE 63.A N GLN 59.A O no hydrogen 2.990 N/A SER 64.A N GLU 60.A O no hydrogen 3.016 N/A ILE 65.A N ASP 61.A O no hydrogen 2.758 N/A TRP 66.A N VAL 62.A O no hydrogen 2.848 N/A ASP 67.A N ILE 63.A O no hydrogen 2.760 N/A GLN 68.A N SER 64.A O no hydrogen 3.237 N/A GLN 68.A N ILE 65.A O no hydrogen 3.151 N/A CYS 69.A N ILE 65.A O no hydrogen 2.744 N/A CYS 69.A SG ILE 65.A O no hydrogen 3.019 N/A LEU 70.A N TRP 66.A O no hydrogen 2.781 N/A LYS 71.A NZ ASP 67.A O no hydrogen 3.103 N/A CYS 73.A N ILE 278.A O no hydrogen 2.856 N/A VAL 74.A N ILE 278.A O no hydrogen 3.275 N/A LYS 75.A N LEU 82.A O no hydrogen 2.842 N/A LYS 75.A NZ GLU 273.A OE1 no hydrogen 3.499 N/A LEU 76.A N LYS 276.A O no hydrogen 2.733 N/A THR 77.A N SER 80.A O no hydrogen 2.927 N/A SER 80.A N THR 77.A O no hydrogen 3.456 N/A LEU 82.A N LYS 75.A O no hydrogen 2.908 N/A GLN 84.A N CYS 73.A O no hydrogen 2.892 N/A GLN 84.A NE2 PRO 72.A O no hydrogen 2.845 N/A CYS 86.A SG GLN 84.A O no hydrogen 3.917 N/A LYS 88.A NZ GLU 239.A OE1 no hydrogen 3.167 N/A LYS 88.A NZ GLU 239.A OE2 no hydrogen 3.533 N/A LYS 88.A NZ ALA 280.A O no hydrogen 3.192 N/A LYS 88.A NZ PRO 281.A O no hydrogen 3.173 N/A ASP 92.A N GLU 18.A OE2 no hydrogen 2.771 N/A ILE 96.A N ILE 132.A O no hydrogen 2.986 N/A HIS 97.A N ALA 9.A O no hydrogen 2.809 N/A HIS 97.A ND1 THR 129.A O no hydrogen 2.798 N/A TYR 98.A N THR 129.A OG1 no hydrogen 2.959 N/A TYR 98.A OH ASP 61.A OD2 no hydrogen 2.690 N/A CYS 99.A N PHE 7.A O no hydrogen 2.777 N/A ALA 100.A N GLN 127.A O no hydrogen 2.889 N/A TYR 104.A N PRO 101.A O no hydrogen 3.263 N/A ALA 105.A N VAL 333.A O no hydrogen 2.778 N/A ILE 106.A N VAL 126.A O no hydrogen 3.325 N/A LEU 107.A N LYS 331.A O no hydrogen 2.815 N/A LYS 108.A N SER 124.A O no hydrogen 2.837 N/A CYS 109.A N LYS 329.A O no hydrogen 2.759 N/A ASN 110.A N ASN 122.A O no hydrogen 2.722 N/A ASN 110.A ND2 ASN 122.A O no hydrogen 3.493 N/A ASN 110.A ND2 SER 124.A OG no hydrogen 3.165 N/A ASN 111.A ND2 ASN 121.A OD1 no hydrogen 3.179 N/A THR 113.A N ASN 111.A OD1 no hydrogen 2.911 N/A THR 113.A OG1 ASN 111.A OD1 no hydrogen 3.334 N/A PHE 114.A N ASN 111.A O no hydrogen 3.302 N/A LYS 117.A N ASN 115.A OD1 no hydrogen 2.942 N/A LYS 117.A NZ LYS 156.A O no hydrogen 3.332 N/A GLY 118.A N PHE 47.A O no hydrogen 2.988 N/A CYS 120.A N GLU 45.A O no hydrogen 2.745 N/A CYS 120.A SG ASN 122.A O no hydrogen 3.569 N/A SER 124.A N LYS 108.A O no hydrogen 3.003 N/A SER 124.A OG GLU 37.A OE2 no hydrogen 2.868 N/A THR 125.A N VAL 38.A O no hydrogen 2.871 N/A THR 125.A OG1 VAL 38.A O no hydrogen 3.461 N/A VAL 126.A N ILE 106.A O no hydrogen 2.980 N/A THR 129.A N TYR 98.A O no hydrogen 2.788 N/A THR 129.A OG1 HIS 130.A O no hydrogen 2.991 N/A HIS 130.A N TYR 330.A OH no hydrogen 3.109 N/A HIS 130.A ND1 TYR 330.A OH no hydrogen 2.571 N/A ILE 132.A N ILE 96.A O no hydrogen 2.775 N/A VAL 135.A N LYS 133.A O no hydrogen 2.906 N/A SER 137.A OG LEU 140.A O no hydrogen 2.689 N/A THR 138.A N SER 233.A O no hydrogen 3.033 N/A THR 138.A OG1 GLU 228.A O no hydrogen 2.589 N/A THR 138.A OG1 THR 231.A O no hydrogen 3.041 N/A GLN 139.A N SER 315.A O no hydrogen 2.831 N/A GLN 139.A NE2 ILE 229.A O no hydrogen 2.864 N/A LEU 140.A N THR 138.A O no hydrogen 2.805 N/A LEU 141.A N GLY 295.A O no hydrogen 2.897 N/A ASN 143.A N ASP 292.A O no hydrogen 2.769 N/A GLY 144.A N THR 294.A OG1 no hydrogen 3.239 N/A SER 145.A N GLU 326.A OE2 no hydrogen 2.755 N/A SER 145.A OG GLU 326.A OE1 no hydrogen 2.662 N/A SER 145.A OG GLU 326.A OE2 no hydrogen 3.138 N/A ALA 147.A N LEU 169.A O no hydrogen 2.737 N/A VAL 152.A N GLN 168.A O no hydrogen 3.126 N/A ARG 154.A N ILE 166.A O no hydrogen 2.780 N/A ARG 154.A NH1 GLN 168.A OE1 no hydrogen 3.122 N/A ARG 154.A NH2 PHE 114.A O no hydrogen 3.388 N/A ARG 154.A NH2 GLN 168.A OE1 no hydrogen 3.080 N/A ASN 157.A N SER 155.A OG no hydrogen 2.928 N/A ARG 159.A N ASN 157.A OD1 no hydrogen 2.990 N/A ARG 159.A NH1 HIS 211.A O no hydrogen 2.739 N/A ARG 159.A NH2 HIS 211.A O no hydrogen 2.778 N/A ASP 160.A N ASN 157.A O no hydrogen 2.855 N/A ALA 162.A N ASP 160.A OD1 no hydrogen 3.068 N/A LYS 163.A N ASP 160.A O no hydrogen 3.004 N/A ILE 165.A N LEU 298.A O no hydrogen 2.817 N/A ILE 166.A N ARG 154.A O no hydrogen 2.805 N/A VAL 167.A N LEU 296.A O no hydrogen 2.861 N/A GLN 168.A N VAL 152.A O no hydrogen 2.973 N/A GLN 168.A NE2 SER 145.A O no hydrogen 3.151 N/A LEU 169.A N THR 294.A O no hydrogen 2.913 N/A GLN 170.A NE2 GLU 148.A O no hydrogen 2.510 N/A LYS 171.A NZ GLU 199.A OE2 no hydrogen 3.365 N/A VAL 173.A N ILE 293.A O no hydrogen 3.143 N/A ILE 175.A N SER 291.A O no hydrogen 2.978 N/A VAL 176.A N GLN 191.A O no hydrogen 3.130 N/A CYS 177.A N CYS 289.A O no hydrogen 2.914 N/A THR 178.A N TYR 189.A O no hydrogen 2.833 N/A THR 178.A OG1 THR 288.A OG1 no hydrogen 2.993 N/A ARG 179.A N ILE 287.A O no hydrogen 2.805 N/A ARG 179.A NE GLY 285.A O no hydrogen 3.371 N/A ARG 179.A NH1 ILE 185.A O no hydrogen 2.829 N/A ARG 179.A NH1 ILE 283.A O no hydrogen 3.530 N/A ARG 179.A NH2 ILE 283.A O no hydrogen 2.767 N/A ARG 179.A NH2 GLY 285.A O no hydrogen 2.653 N/A ARG 186.A N ASP 184.A OD1 no hydrogen 2.892 N/A ARG 186.A NH2 GLN 266.A OE1 no hydrogen 2.890 N/A GLN 187.A N ASP 184.A O no hydrogen 3.083 N/A ALA 188.A N CYS 262.A O no hydrogen 2.912 N/A TYR 189.A N THR 178.A O no hydrogen 3.059 N/A CYS 190.A N LEU 260.A O no hydrogen 2.825 N/A GLN 191.A N VAL 176.A O no hydrogen 2.822 N/A ILE 192.A N ILE 258.A O no hydrogen 3.044 N/A GLY 194.A N ALA 256.A O no hydrogen 2.948 N/A ASN 196.A N SER 193.A OG no hydrogen 2.943 N/A TRP 197.A N SER 193.A O no hydrogen 2.815 N/A TRP 197.A NE1 LEU 248.A O no hydrogen 2.810 N/A SER 198.A N GLY 194.A O no hydrogen 2.763 N/A GLU 199.A N ARG 195.A O no hydrogen 3.025 N/A ALA 200.A N ASN 196.A O no hydrogen 3.059 N/A VAL 201.A N TRP 197.A O no hydrogen 2.930 N/A ASN 202.A N SER 198.A O no hydrogen 2.916 N/A GLN 203.A N GLU 199.A O no hydrogen 3.008 N/A VAL 204.A N ALA 200.A O no hydrogen 2.859 N/A LYS 205.A N VAL 201.A O no hydrogen 2.765 N/A LYS 205.A NZ ASP 251.A OD1 no hydrogen 2.718 N/A LYS 206.A N ASN 202.A O no hydrogen 2.975 N/A LYS 207.A N GLN 203.A O no hydrogen 3.076 N/A LYS 207.A NZ GLU 150.A OE2 no hydrogen 2.980 N/A LYS 207.A NZ GLU 210.A OE1 no hydrogen 3.037 N/A LYS 207.A NZ GLU 210.A OE2 no hydrogen 3.400 N/A LEU 208.A N VAL 204.A O no hydrogen 2.875 N/A LYS 209.A N LYS 205.A O no hydrogen 2.883 N/A LYS 209.A NZ LYS 215.A O no hydrogen 3.293 N/A GLU 210.A N LYS 206.A O no hydrogen 3.333 N/A HIS 211.A N LEU 208.A O no hydrogen 2.953 N/A PHE 212.A N LEU 208.A O no hydrogen 3.255 N/A PHE 212.A N LYS 209.A O no hydrogen 3.053 N/A LYS 215.A NZ GLU 310.A OE2 no hydrogen 3.522 N/A ASN 216.A N ASN 308.A O no hydrogen 2.965 N/A SER 218.A N GLU 310.A O no hydrogen 2.869 N/A SER 218.A OG ASP 251.A OD1 no hydrogen 3.528 N/A SER 218.A OG ASP 251.A OD2 no hydrogen 2.451 N/A PHE 219.A N ASP 251.A OD1 no hydrogen 2.890 N/A GLN 220.A N PHE 312.A O no hydrogen 2.990 N/A GLY 224.A N SER 222.A OG no hydrogen 3.208 N/A ILE 229.A N ASP 226.A O no hydrogen 2.971 N/A THR 230.A N ASP 226.A O no hydrogen 2.988 N/A THR 230.A OG1 ASP 226.A O no hydrogen 3.515 N/A THR 231.A N LEU 227.A O no hydrogen 2.975 N/A THR 231.A OG1 LEU 227.A O no hydrogen 2.727 N/A HIS 232.A N CYS 243.A O no hydrogen 2.929 N/A HIS 232.A ND1 THR 138.A O no hydrogen 2.803 N/A SER 233.A N THR 138.A OG1 no hydrogen 2.940 N/A SER 233.A OG PHE 241.A O no hydrogen 2.786 N/A PHE 234.A N PHE 241.A O no hydrogen 3.166 N/A CYS 236.A N GLU 239.A O no hydrogen 2.815 N/A GLU 239.A N CYS 236.A O no hydrogen 3.074 N/A PHE 241.A N PHE 234.A O no hydrogen 2.864 N/A TYR 242.A N ARG 263.A O no hydrogen 2.824 N/A TYR 242.A OH GLU 228.A OE2 no hydrogen 2.497 N/A CYS 243.A N HIS 232.A O no hydrogen 2.775 N/A ASN 244.A N PRO 261.A O no hydrogen 2.879 N/A THR 245.A OG1 GLN 139.A OE1 no hydrogen 2.597 N/A SER 246.A N ASN 244.A OD1 no hydrogen 2.808 N/A SER 246.A OG ASN 244.A OD1 no hydrogen 3.115 N/A LEU 248.A N THR 245.A O no hydrogen 2.868 N/A PHE 249.A N THR 245.A O no hydrogen 3.119 N/A ALA 256.A N SER 254.A OG no hydrogen 3.086 N/A ILE 258.A N ILE 192.A O no hydrogen 2.908 N/A LEU 260.A N CYS 190.A O no hydrogen 2.798 N/A CYS 262.A N ALA 188.A O no hydrogen 2.763 N/A CYS 262.A SG LEU 260.A O no hydrogen 3.952 N/A ARG 263.A N TYR 242.A O no hydrogen 2.931 N/A ARG 263.A NH2 ASP 184.A OD2 no hydrogen 3.011 N/A ARG 263.A NH2 GLN 187.A OE1 no hydrogen 3.064 N/A ILE 264.A N ARG 186.A O no hydrogen 2.835 N/A LYS 265.A N PHE 240.A O no hydrogen 3.038 N/A LYS 265.A NZ ILE 267.A O no hydrogen 3.534 N/A GLN 266.A NE2 TYR 279.A O no hydrogen 2.694 N/A ILE 268.A N ALA 277.A O no hydrogen 2.874 N/A ASN 269.A N GLU 228.A OE2 no hydrogen 2.967 N/A ASN 269.A ND2 GLU 228.A OE1 no hydrogen 2.946 N/A ASN 269.A ND2 GLU 228.A OE2 no hydrogen 3.567 N/A MET 270.A N GLY 275.A O no hydrogen 2.887 N/A GLN 272.A N GLN 272.A OE1 no hydrogen 2.737 N/A LYS 276.A N LEU 76.A O no hydrogen 2.812 N/A LYS 276.A NZ ASN 269.A OD1 no hydrogen 2.835 N/A ALA 277.A N ILE 268.A O no hydrogen 2.922 N/A ILE 278.A N VAL 74.A O no hydrogen 2.789 N/A TYR 279.A N GLN 266.A O no hydrogen 2.758 N/A TYR 279.A OH LEU 70.A O no hydrogen 2.648 N/A ILE 283.A N GLU 239.A OE1 no hydrogen 3.165 N/A ILE 287.A N ARG 179.A O no hydrogen 2.956 N/A THR 288.A OG1 THR 178.A OG1 no hydrogen 2.993 N/A CYS 289.A N CYS 177.A O no hydrogen 2.972 N/A SER 291.A N ILE 175.A O no hydrogen 2.783 N/A ASP 292.A N ASN 143.A OD1 no hydrogen 3.059 N/A ILE 293.A N VAL 173.A O no hydrogen 2.827 N/A THR 294.A N LEU 141.A O no hydrogen 2.894 N/A THR 294.A OG1 LEU 141.A O no hydrogen 3.378 N/A GLY 295.A N LEU 141.A O no hydrogen 3.338 N/A LEU 296.A N VAL 167.A O no hydrogen 3.003 N/A LEU 297.A N GLN 139.A O no hydrogen 2.993 N/A LEU 298.A N ILE 165.A O no hydrogen 2.862 N/A LEU 299.A N ARG 313.A O no hydrogen 2.876 N/A ARG 300.A NH1 GLU 310.A OE1 no hydrogen 3.028 N/A ARG 300.A NH2 LEU 158.A O no hydrogen 3.060 N/A ASP 301.A N ILE 311.A O no hydrogen 2.897 N/A THR 305.A OG1 THR 305.A O no hydrogen 2.325 N/A ASN 308.A N THR 305.A O no hydrogen 3.240 N/A ASN 308.A ND2 HIS 214.A O no hydrogen 2.948 N/A THR 309.A OG1 ASP 307.A O no hydrogen 3.534 N/A GLU 310.A N ASN 216.A O no hydrogen 2.885 N/A PHE 312.A N SER 218.A O no hydrogen 2.786 N/A ARG 313.A N LEU 299.A O no hydrogen 2.908 N/A ARG 313.A NE ASP 301.A OD1 no hydrogen 2.893 N/A ARG 313.A NE ASP 301.A OD2 no hydrogen 3.335 N/A ARG 313.A NH1 SER 221.A O no hydrogen 2.889 N/A ARG 313.A NH2 ASP 301.A OD2 no hydrogen 2.851 N/A SER 315.A N LEU 297.A O no hydrogen 2.910 N/A ARG 320.A N ASP 318.A OD1 no hydrogen 3.124 N/A ARG 320.A NE ASP 318.A OD1 no hydrogen 2.953 N/A ARG 320.A NH1 ASP 318.A OD2 no hydrogen 2.699 N/A ASP 321.A N ASP 318.A O no hydrogen 2.983 N/A ASN 322.A ND2 SER 137.A O no hydrogen 3.158 N/A TRP 323.A N MET 319.A O no hydrogen 3.167 N/A TRP 323.A NE1 GLN 59.A OE1 no hydrogen 2.753 N/A ARG 324.A N ARG 320.A O no hydrogen 2.879 N/A ARG 324.A NE MET 49.A O no hydrogen 3.398 N/A ARG 324.A NH1 ASP 321.A OD1 no hydrogen 2.784 N/A SER 325.A N ASP 321.A O no hydrogen 3.050 N/A SER 325.A OG ASN 322.A O no hydrogen 2.567 N/A GLU 326.A N TRP 323.A O no hydrogen 2.971 N/A LEU 327.A N TRP 323.A O no hydrogen 2.865 N/A TYR 328.A N ARG 324.A O no hydrogen 3.031 N/A TYR 330.A N LEU 327.A O no hydrogen 3.034 N/A TYR 330.A OH HIS 130.A ND1 no hydrogen 2.571 N/A LYS 331.A N LEU 107.A O no hydrogen 3.043 N/A LYS 331.A NZ GLU 45.A OE2 no hydrogen 2.755 N/A LYS 331.A NZ ASN 46.A O no hydrogen 2.782 N/A VAL 333.A N ALA 105.A O no hydrogen 2.742 N/A ILE 335.A N GLY 103.A O no hydrogen 2.996 N/A