Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5fed_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): GLU 1.A N GLU 1.A OE2 no hydrogen 2.241 N/A ASN 4.A ND2 TYR 60.A OH no hydrogen 3.368 N/A ASN 4.A ND2 SER 64.A OG no hydrogen 2.950 N/A ALA 6.A N ASN 4.A OD1 no hydrogen 3.057 N/A LEU 11.A N ILE 76.A O no hydrogen 2.774 N/A LYS 12.A N GLU 15.A OE2 no hydrogen 3.163 N/A GLU 15.A N LYS 12.A O no hydrogen 2.919 N/A PHE 16.A N GLU 13.A O no hydrogen 3.444 N/A LYS 17.A N LEU 31.A O no hydrogen 2.964 N/A LYS 18.A NZ GLU 47.A OE1 no hydrogen 3.110 N/A LYS 18.A NZ GLU 47.A OE2 no hydrogen 3.122 N/A ILE 19.A N LYS 29.A O no hydrogen 2.860 N/A LEU 22.A N VAL 27.A O no hydrogen 2.790 N/A GLY 23.A N VAL 27.A O no hydrogen 3.478 N/A VAL 27.A N GLY 23.A O no hydrogen 3.122 N/A TYR 28.A N ILE 45.A O no hydrogen 2.827 N/A TYR 28.A OH GLU 47.A OE1 no hydrogen 2.972 N/A LYS 29.A N LYS 20.A O no hydrogen 2.741 N/A GLY 30.A N VAL 43.A O no hydrogen 2.877 N/A LEU 31.A N LYS 17.A O no hydrogen 2.970 N/A TRP 32.A N ILE 41.A O no hydrogen 2.663 N/A TRP 32.A NE1 GLU 15.A OE2 no hydrogen 3.234 N/A ILE 33.A N GLU 15.A O no hydrogen 2.778 N/A GLU 35.A N GLU 35.A OE2 no hydrogen 2.182 N/A GLU 37.A N PRO 34.A O no hydrogen 3.106 N/A LYS 40.A N ASP 280.A O no hydrogen 2.929 N/A ILE 41.A N TRP 32.A O no hydrogen 2.735 N/A VAL 43.A N GLY 30.A O no hydrogen 2.872 N/A ALA 44.A N THR 86.A O no hydrogen 2.831 N/A ILE 45.A N TYR 28.A O no hydrogen 2.855 N/A LYS 46.A N LEU 84.A O no hydrogen 2.768 N/A LYS 46.A NZ GLU 58.A OE2 no hydrogen 2.951 N/A GLU 47.A N THR 26.A O no hydrogen 2.871 N/A ASN 52.A N SER 48.A O no hydrogen 3.149 N/A ASN 52.A ND2 SER 48.A O no hydrogen 2.207 N/A LYS 53.A N PRO 49.A O no hydrogen 3.074 N/A GLU 54.A N LYS 50.A O no hydrogen 3.185 N/A ILE 55.A N ALA 51.A O no hydrogen 3.065 N/A LEU 56.A N ASN 52.A O no hydrogen 2.994 N/A ASP 57.A N LYS 53.A O no hydrogen 2.998 N/A GLU 58.A N GLU 54.A O no hydrogen 3.128 N/A ALA 59.A N ILE 55.A O no hydrogen 2.973 N/A TYR 60.A N LEU 56.A O no hydrogen 2.879 N/A VAL 61.A N ASP 57.A O no hydrogen 3.136 N/A MET 62.A N GLU 58.A O no hydrogen 2.852 N/A ALA 63.A N ALA 59.A O no hydrogen 2.843 N/A SER 64.A N VAL 61.A O no hydrogen 2.952 N/A SER 64.A OG TYR 60.A O no hydrogen 2.656 N/A ASP 66.A N TYR 123.A OH no hydrogen 2.916 N/A HIS 69.A N ASN 67.A OD1 no hydrogen 2.795 N/A HIS 69.A ND1 VAL 147.A O no hydrogen 3.105 N/A VAL 70.A N ASN 67.A O no hydrogen 3.090 N/A CYS 71.A N ILE 149.A O no hydrogen 2.778 N/A ARG 72.A NH1 TYR 287.A O no hydrogen 3.439 N/A ARG 72.A NH2 TYR 287.A O no hydrogen 2.905 N/A LEU 74.A N ILE 85.A O no hydrogen 2.938 N/A GLY 75.A N ILE 85.A O no hydrogen 3.354 N/A ILE 76.A N ARG 9.A O no hydrogen 2.943 N/A CYS 77.A N GLN 83.A O no hydrogen 3.034 N/A CYS 77.A SG LEU 11.A O no hydrogen 3.448 N/A THR 81.A OG1 GLU 47.A OE2 no hydrogen 2.663 N/A VAL 82.A N THR 79.A OG1 no hydrogen 3.115 N/A GLN 83.A N CYS 77.A O no hydrogen 3.127 N/A GLN 83.A NE2 GLU 47.A OE2 no hydrogen 3.215 N/A LEU 84.A N LYS 46.A O no hydrogen 3.036 N/A ILE 85.A N GLY 75.A O no hydrogen 2.981 N/A THR 86.A N ALA 44.A O no hydrogen 2.891 N/A THR 86.A OG1 ALA 44.A O no hydrogen 3.519 N/A THR 86.A OG1 GLN 87.A O no hydrogen 3.557 N/A GLN 87.A NE2 ASP 285.A OD2 no hydrogen 2.973 N/A LEU 88.A N PRO 42.A O no hydrogen 3.365 N/A PHE 91.A N VAL 141.A O no hydrogen 3.209 N/A GLY 92.A N MET 89.A O no hydrogen 3.002 N/A LEU 94.A N VAL 139.A O no hydrogen 2.674 N/A TYR 97.A N CYS 93.A O no hydrogen 3.155 N/A VAL 98.A N LEU 94.A O no hydrogen 2.958 N/A ARG 99.A N LEU 95.A O no hydrogen 3.073 N/A ARG 99.A NE GLY 203.A O no hydrogen 2.895 N/A ARG 99.A NH2 GLY 203.A O no hydrogen 3.202 N/A GLU 100.A N ASP 96.A O no hydrogen 2.888 N/A HIS 101.A N TYR 97.A O no hydrogen 2.977 N/A HIS 101.A ND1 TYR 97.A O no hydrogen 3.271 N/A LYS 102.A NZ PHE 202.A O no hydrogen 3.222 N/A ASN 104.A N HIS 101.A O no hydrogen 2.793 N/A SER 107.A N ASP 276.A OD1 no hydrogen 2.852 N/A SER 107.A OG ASP 276.A OD1 no hydrogen 2.774 N/A LEU 110.A N GLY 106.A O no hydrogen 3.214 N/A LEU 111.A N SER 107.A O no hydrogen 2.970 N/A ASN 112.A N GLN 108.A O no hydrogen 3.098 N/A TRP 113.A N TYR 109.A O no hydrogen 2.986 N/A TRP 113.A NE1 PRO 144.A O no hydrogen 2.943 N/A CYS 114.A N LEU 110.A O no hydrogen 3.099 N/A CYS 114.A SG LEU 110.A O no hydrogen 3.500 N/A VAL 115.A N LEU 111.A O no hydrogen 2.992 N/A GLN 116.A N ASN 112.A O no hydrogen 2.840 N/A GLN 116.A NE2 GLN 145.A O no hydrogen 2.932 N/A ILE 117.A N TRP 113.A O no hydrogen 2.875 N/A ALA 118.A N CYS 114.A O no hydrogen 3.098 N/A LYS 119.A N VAL 115.A O no hydrogen 2.886 N/A GLY 120.A N GLN 116.A O no hydrogen 2.918 N/A MET 121.A N ILE 117.A O no hydrogen 2.932 N/A ASN 122.A N ALA 118.A O no hydrogen 2.787 N/A TYR 123.A N LYS 119.A O no hydrogen 3.008 N/A LEU 124.A N GLY 120.A O no hydrogen 2.964 N/A GLU 125.A N MET 121.A O no hydrogen 2.860 N/A ASP 126.A N ASN 122.A O no hydrogen 2.976 N/A ARG 127.A N TYR 123.A O no hydrogen 2.996 N/A ARG 128.A N GLU 125.A O no hydrogen 2.774 N/A ARG 128.A NE LEU 158.A O no hydrogen 3.298 N/A ARG 128.A NH2 LEU 158.A O no hydrogen 3.447 N/A LEU 129.A N LEU 124.A O no hydrogen 2.711 N/A VAL 130.A N LYS 156.A O no hydrogen 3.052 N/A HIS 131.A N ASP 188.A OD1 no hydrogen 2.785 N/A HIS 131.A NE2 THR 150.A O no hydrogen 2.908 N/A ARG 132.A N ASP 188.A OD2 no hydrogen 3.049 N/A ARG 132.A NH1 LEU 154.A O no hydrogen 2.744 N/A ASP 133.A N HIS 131.A ND1 no hydrogen 2.922 N/A ALA 136.A N GLU 198.A OE2 no hydrogen 2.989 N/A ARG 137.A NH1 ASP 133.A OD1 no hydrogen 3.130 N/A ASN 138.A N ALA 135.A O no hydrogen 2.731 N/A ASN 138.A ND2 ASP 133.A O no hydrogen 2.667 N/A VAL 139.A N ALA 136.A O no hydrogen 3.237 N/A LEU 140.A N LYS 148.A O no hydrogen 2.749 N/A VAL 141.A N GLY 92.A O no hydrogen 2.909 N/A LYS 142.A N HIS 146.A O no hydrogen 3.004 N/A LYS 142.A NZ ASP 283.A OD1 no hydrogen 3.452 N/A LYS 142.A NZ ASP 285.A OD2 no hydrogen 2.505 N/A THR 143.A N HIS 146.A O no hydrogen 3.263 N/A THR 143.A OG1 GLN 145.A OE1 no hydrogen 3.399 N/A GLN 145.A N THR 143.A OG1 no hydrogen 3.053 N/A GLN 145.A NE2 TYR 109.A OH no hydrogen 2.871 N/A HIS 146.A N THR 143.A O no hydrogen 2.880 N/A HIS 146.A NE2 PRO 68.A O no hydrogen 2.759 N/A VAL 147.A N GLN 116.A OE1 no hydrogen 2.825 N/A LYS 148.A N LEU 140.A O no hydrogen 2.911 N/A LYS 148.A NZ GLN 87.A OE1 no hydrogen 2.666 N/A LYS 148.A NZ ASP 285.A OD1 no hydrogen 2.764 N/A LYS 148.A NZ ASP 285.A OD2 no hydrogen 3.393 N/A ILE 149.A N HIS 69.A O no hydrogen 2.797 N/A THR 150.A N ASN 138.A O no hydrogen 2.847 N/A ALA 155.A N PHE 152.A O no hydrogen 3.003 N/A LYS 156.A N VAL 130.A O no hydrogen 3.038 N/A LYS 156.A NZ ALA 155.A O no hydrogen 3.458 N/A LEU 158.A N ARG 128.A O no hydrogen 3.092 N/A TYR 161.A N TYR 183.A O no hydrogen 2.962 N/A ALA 163.A N ARG 181.A O no hydrogen 3.317 N/A LYS 171.A NZ PRO 206.A O no hydrogen 3.431 N/A LYS 171.A NZ TYR 207.A O no hydrogen 2.922 N/A LYS 171.A NZ ILE 210.A O no hydrogen 2.806 N/A TRP 172.A N PRO 169.A O no hydrogen 3.307 N/A TRP 172.A NE1 GLU 198.A OE2 no hydrogen 2.677 N/A MET 173.A N ILE 170.A O no hydrogen 3.031 N/A GLU 176.A N GLU 176.A OE1 no hydrogen 3.110 N/A SER 177.A N ALA 174.A O no hydrogen 3.243 N/A SER 177.A OG ILE 182.A O no hydrogen 2.526 N/A ILE 178.A N ALA 174.A O no hydrogen 3.174 N/A LEU 179.A N LEU 175.A O no hydrogen 3.018 N/A HIS 180.A N GLU 176.A O no hydrogen 2.883 N/A ARG 181.A N SER 177.A O no hydrogen 2.902 N/A TYR 183.A N TYR 161.A O no hydrogen 3.153 N/A THR 184.A N SER 187.A OG no hydrogen 2.919 N/A GLN 186.A NE2 ALA 247.A O no hydrogen 3.208 N/A GLN 186.A NE2 PRO 251.A O no hydrogen 2.994 N/A SER 187.A N THR 184.A OG1 no hydrogen 3.043 N/A SER 187.A OG THR 184.A O no hydrogen 2.908 N/A ASP 188.A N THR 184.A O no hydrogen 2.998 N/A VAL 189.A N HIS 185.A O no hydrogen 3.115 N/A TRP 190.A N GLN 186.A O no hydrogen 3.432 N/A SER 191.A N SER 187.A O no hydrogen 3.501 N/A SER 191.A OG TRP 172.A O no hydrogen 2.613 N/A SER 191.A OG SER 187.A O no hydrogen 3.459 N/A TYR 192.A N ASP 188.A O no hydrogen 2.912 N/A TYR 192.A OH CYS 114.A O no hydrogen 2.757 N/A GLY 193.A N VAL 189.A O no hydrogen 2.912 N/A VAL 194.A N TRP 190.A O no hydrogen 3.106 N/A THR 195.A N SER 191.A O no hydrogen 2.803 N/A THR 195.A OG1 SER 191.A O no hydrogen 2.648 N/A VAL 196.A N TYR 192.A O no hydrogen 2.835 N/A TRP 197.A N GLY 193.A O no hydrogen 3.082 N/A TRP 197.A NE1 PRO 226.A O no hydrogen 2.834 N/A GLU 198.A N VAL 194.A O no hydrogen 2.740 N/A LEU 199.A N THR 195.A O no hydrogen 3.007 N/A MET 200.A N VAL 196.A O no hydrogen 2.804 N/A THR 201.A N TRP 197.A O no hydrogen 3.016 N/A THR 201.A OG1 TRP 197.A O no hydrogen 2.955 N/A THR 201.A OG1 GLU 198.A O no hydrogen 3.169 N/A PHE 202.A N LEU 199.A O no hydrogen 2.839 N/A GLY 203.A N GLU 198.A O no hydrogen 2.676 N/A SER 204.A N THR 201.A OG1 no hydrogen 3.115 N/A SER 204.A OG THR 201.A O no hydrogen 3.278 N/A SER 213.A OG GLU 214.A OE2 no hydrogen 2.947 N/A GLU 214.A N PRO 211.A O no hydrogen 3.113 N/A GLU 214.A N GLU 214.A OE2 no hydrogen 2.276 N/A ILE 215.A N ALA 212.A O no hydrogen 3.148 N/A SER 217.A N GLU 214.A O no hydrogen 3.044 N/A SER 217.A OG GLU 214.A O no hydrogen 2.671 N/A ILE 218.A N GLU 214.A O no hydrogen 3.117 N/A LEU 219.A N ILE 215.A O no hydrogen 2.968 N/A GLU 220.A N SER 216.A O no hydrogen 3.105 N/A LYS 221.A N SER 217.A O no hydrogen 2.896 N/A GLY 222.A N LEU 219.A O no hydrogen 3.309 N/A GLU 223.A N ILE 218.A O no hydrogen 3.280 N/A ARG 224.A NE GLU 223.A O no hydrogen 2.720 N/A ARG 224.A NH2 LEU 219.A O no hydrogen 3.169 N/A GLN 227.A NE2 CYS 231.A O no hydrogen 3.036 N/A CYS 231.A N PRO 228.A O no hydrogen 2.864 N/A THR 232.A N TYR 270.A O no hydrogen 3.305 N/A THR 232.A OG1 TYR 270.A O no hydrogen 2.730 N/A TYR 236.A N THR 232.A O no hydrogen 2.949 N/A TYR 236.A OH LEU 225.A O no hydrogen 2.629 N/A MET 237.A N ILE 233.A O no hydrogen 2.709 N/A ILE 238.A N VAL 235.A O no hydrogen 3.037 N/A MET 239.A N VAL 235.A O no hydrogen 3.361 N/A VAL 240.A N TYR 236.A O no hydrogen 3.033 N/A LYS 241.A N MET 237.A O no hydrogen 2.967 N/A CYS 242.A N ILE 238.A O no hydrogen 3.114 N/A CYS 242.A SG VAL 189.A O no hydrogen 3.786 N/A CYS 242.A SG ILE 238.A O no hydrogen 3.443 N/A TRP 243.A N VAL 240.A O no hydrogen 2.831 N/A MET 244.A N LYS 241.A O no hydrogen 3.334 N/A SER 249.A N ASP 246.A O no hydrogen 2.915 N/A SER 249.A OG ASP 246.A OD1 no hydrogen 2.682 N/A ARG 250.A N ALA 247.A O no hydrogen 3.202 N/A ARG 250.A NE GLN 186.A O no hydrogen 3.389 N/A ARG 250.A NH1 GLU 176.A OE1 no hydrogen 3.057 N/A ARG 250.A NH1 MET 244.A O no hydrogen 2.734 N/A ARG 250.A NH2 GLU 176.A OE1 no hydrogen 2.891 N/A ARG 250.A NH2 GLN 186.A O no hydrogen 3.138 N/A LYS 252.A N GLU 255.A OE1 no hydrogen 3.091 N/A LYS 252.A NZ GLU 125.A OE1 no hydrogen 2.557 N/A LYS 252.A NZ GLN 186.A OE1 no hydrogen 3.386 N/A LEU 256.A N LYS 252.A O no hydrogen 2.904 N/A ILE 257.A N PHE 253.A O no hydrogen 2.917 N/A ILE 258.A N ARG 254.A O no hydrogen 3.378 N/A GLU 259.A N GLU 255.A O no hydrogen 2.980 N/A PHE 260.A N LEU 256.A O no hydrogen 3.049 N/A SER 261.A N ILE 257.A O no hydrogen 2.871 N/A SER 261.A OG ILE 257.A O no hydrogen 2.738 N/A LYS 262.A N ILE 258.A O no hydrogen 2.901 N/A LYS 262.A NZ GLU 259.A OE1 no hydrogen 3.278 N/A MET 263.A N GLU 259.A O no hydrogen 3.017 N/A ALA 264.A N PHE 260.A O no hydrogen 2.764 N/A ARG 265.A N LYS 262.A O no hydrogen 3.132 N/A ASP 266.A N MET 263.A O no hydrogen 3.102 N/A ARG 269.A N ASP 266.A O no hydrogen 3.054 N/A TYR 270.A N PRO 267.A O no hydrogen 3.027 N/A LEU 271.A N PRO 267.A O no hydrogen 2.958 N/A VAL 272.A N ILE 230.A O no hydrogen 2.907 N/A ASP 276.A N ILE 273.A O no hydrogen 3.254 N/A VAL 282.A N LYS 40.A O no hydrogen 3.006 N/A ASP 285.A N ASP 283.A OD1 no hydrogen 3.364 N/A GLU 286.A N ASP 283.A O no hydrogen 2.923 N/A TYR 287.A N ALA 284.A O no hydrogen 2.947 N/A TYR 287.A OH GLU 37.A OE2 no hydrogen 2.090 N/A