Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5h8q_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASN 1.A ND2 LYS 67.A O no hydrogen 2.906 N/A HIS 2.A ND1 THR 69.A OG1 no hydrogen 2.852 N/A LEU 3.A N THR 69.A O no hydrogen 2.900 N/A SER 4.A OG ARG 99.A O no hydrogen 2.793 N/A ILE 5.A N ASP 71.A O no hydrogen 3.009 N/A VAL 6.A N MET 102.A O no hydrogen 3.005 N/A THR 7.A N TYR 73.A O no hydrogen 2.885 N/A THR 7.A OG1 VAL 104.A O no hydrogen 2.718 N/A LEU 8.A N THR 7.A OG1 no hydrogen 2.802 N/A GLU 10.A N VAL 14.A O no hydrogen 2.852 N/A PHE 13.A N GLU 10.A O no hydrogen 2.929 N/A VAL 14.A N GLU 10.A O no hydrogen 3.106 N/A ILE 15.A N LYS 52.A O no hydrogen 2.775 N/A VAL 16.A N GLU 9.A OE2 no hydrogen 3.129 N/A GLU 17.A N CYS 50.A O no hydrogen 2.749 N/A CYS 24.A SG LYS 49.A O no hydrogen 3.420 N/A THR 28.A N VAL 25.A O no hydrogen 3.258 N/A THR 28.A OG1 VAL 25.A O no hydrogen 2.718 N/A VAL 29.A N CYS 51.A O no hydrogen 2.835 N/A CYS 31.A N LYS 49.A O no hydrogen 3.044 N/A ARG 32.A N LEU 72.A O no hydrogen 3.064 N/A ARG 32.A NE ASP 71.A OD1 no hydrogen 2.920 N/A ARG 32.A NE ASP 71.A OD2 no hydrogen 3.395 N/A ARG 32.A NH2 ASP 71.A OD2 no hydrogen 3.066 N/A LYS 33.A N VAL 47.A O no hydrogen 2.964 N/A VAL 35.A N MET 45.A O no hydrogen 2.792 N/A LYS 36.A NZ ASN 42.A O no hydrogen 3.242 N/A ILE 37.A N GLU 43.A O no hydrogen 3.003 N/A SER 40.A N ASN 38.A OD1 no hydrogen 2.803 N/A GLU 43.A N THR 41.A OG1 no hydrogen 3.186 N/A MET 45.A N VAL 35.A O no hydrogen 2.825 N/A VAL 47.A N LYS 33.A O no hydrogen 2.802 N/A LYS 49.A N CYS 31.A O no hydrogen 2.808 N/A LYS 49.A NZ ASP 18.A OD1 no hydrogen 2.762 N/A CYS 50.A N GLU 17.A O no hydrogen 2.868 N/A CYS 51.A N VAL 29.A O no hydrogen 2.826 N/A LYS 52.A N ILE 15.A O no hydrogen 2.925 N/A LYS 52.A NZ GLU 17.A OE2 no hydrogen 2.774 N/A PHE 54.A N PRO 12.A O no hydrogen 2.965 N/A CYS 55.A N PHE 13.A O no hydrogen 2.818 N/A ASP 57.A N GLY 53.A O no hydrogen 2.985 N/A ILE 58.A N PHE 54.A O no hydrogen 3.176 N/A LEU 59.A N CYS 55.A O no hydrogen 2.957 N/A LYS 60.A N ILE 56.A O no hydrogen 2.896 N/A LYS 60.A NZ ASN 27.A O no hydrogen 3.293 N/A LYS 60.A NZ ASP 57.A OD1 no hydrogen 3.161 N/A LYS 61.A N ASP 57.A O no hydrogen 3.075 N/A LYS 61.A NZ GLU 263.A OE1 no hydrogen 2.765 N/A LEU 62.A N ILE 58.A O no hydrogen 2.865 N/A SER 63.A N LEU 59.A O no hydrogen 2.853 N/A SER 63.A OG.A PHE 68.A O no hydrogen 2.629 N/A SER 63.A OG.B LEU 59.A O no hydrogen 3.429 N/A SER 63.A OG.B LYS 60.A O no hydrogen 2.734 N/A ARG 64.A N LYS 60.A O no hydrogen 3.301 N/A ARG 64.A NH1 THR 65.A OG1 no hydrogen 3.082 N/A THR 65.A N LYS 61.A O no hydrogen 3.046 N/A THR 65.A OG1 LYS 61.A O no hydrogen 3.062 N/A VAL 66.A N LEU 62.A O no hydrogen 2.791 N/A PHE 68.A N SER 63.A O no hydrogen 3.062 N/A THR 69.A N ASN 1.A O no hydrogen 2.946 N/A THR 69.A OG1 HIS 2.A ND1 no hydrogen 2.852 N/A ASP 71.A N LEU 3.A O no hydrogen 2.936 N/A TYR 73.A N ILE 5.A O no hydrogen 2.907 N/A TYR 73.A OH GLU 94.A OE1 no hydrogen 2.705 N/A LEU 74.A N ARG 32.A O no hydrogen 2.808 N/A VAL 75.A N THR 7.A O no hydrogen 3.033 N/A HIS 80.A NE2 GLU 10.A OE1 no hydrogen 3.004 N/A HIS 80.A NE2 SER 106.A OG no hydrogen 3.283 N/A LYS 82.A N ASN 89.A OD1 no hydrogen 3.078 N/A LYS 82.A NZ ASN 163.A OD1 no hydrogen 2.816 N/A VAL 84.A N VAL 87.A O no hydrogen 2.928 N/A VAL 87.A N VAL 84.A O no hydrogen 2.967 N/A ASN 89.A N LYS 82.A O no hydrogen 2.908 N/A GLY 90.A N ASN 77.A O no hydrogen 2.737 N/A MET 91.A N LYS 79.A O no hydrogen 2.824 N/A ILE 92.A N HIS 80.A O no hydrogen 3.201 N/A GLY 93.A N ASN 89.A O no hydrogen 3.086 N/A GLU 94.A N GLY 90.A O no hydrogen 3.112 N/A VAL 95.A N MET 91.A O no hydrogen 3.262 N/A VAL 96.A N ILE 92.A O no hydrogen 2.868 N/A TYR 97.A N GLY 93.A O no hydrogen 2.926 N/A GLN 98.A N VAL 95.A O no hydrogen 3.003 N/A ARG 99.A N GLU 94.A O no hydrogen 2.817 N/A ARG 99.A NE GLU 94.A OE1 no hydrogen 3.169 N/A ARG 99.A NE GLU 94.A OE2 no hydrogen 3.130 N/A ARG 99.A NH2 GLU 94.A OE2 no hydrogen 3.437 N/A ALA 100.A N GLU 94.A O no hydrogen 3.197 N/A VAL 101.A N SER 4.A O no hydrogen 2.827 N/A ALA 103.A N ALA 240.A O no hydrogen 2.868 N/A VAL 104.A N VAL 6.A O no hydrogen 2.957 N/A SER 106.A OG GLU 10.A OE1 no hydrogen 2.621 N/A SER 106.A OG HIS 80.A NE2 no hydrogen 3.283 N/A THR 108.A OG1 ASP 207.A OD1 no hydrogen 3.548 N/A ILE 109.A N GLY 236.A O no hydrogen 2.952 N/A ARG 113.A N ASN 110.A OD1 no hydrogen 2.948 N/A ARG 113.A NH1 THR 108.A O no hydrogen 2.886 N/A ARG 113.A NH2 GLY 81.A O no hydrogen 2.916 N/A SER 114.A N ASN 110.A O no hydrogen 3.013 N/A SER 114.A OG ASN 110.A O no hydrogen 2.887 N/A GLU 115.A N GLU 111.A O no hydrogen 3.256 N/A GLU 115.A N GLU 112.A O no hydrogen 3.341 N/A VAL 116.A N ARG 113.A O no hydrogen 3.015 N/A VAL 117.A N ARG 113.A O no hydrogen 2.964 N/A ASP 118.A N LEU 241.A O no hydrogen 2.926 N/A SER 120.A N ILE 239.A O no hydrogen 2.847 N/A SER 120.A OG VAL 121.A O no hydrogen 2.777 N/A VAL 121.A N ASP 252.A OD1 no hydrogen 2.841 N/A PHE 123.A N TYR 237.A O no hydrogen 3.035 N/A THR 126.A N THR 235.A O no hydrogen 2.988 N/A THR 126.A OG1 ASP 207.A OD1 no hydrogen 2.664 N/A THR 126.A OG1 ASP 207.A OD2 no hydrogen 3.277 N/A ILE 128.A N PHE 232.A O no hydrogen 2.769 N/A SER 129.A N TYR 206.A O no hydrogen 2.901 N/A SER 129.A OG TYR 230.A O no hydrogen 2.859 N/A MET 131.A N PHE 204.A O no hydrogen 2.831 N/A VAL 132.A N VAL 224.A O no hydrogen 2.813 N/A ARG 134.A N LYS 222.A O no hydrogen 2.761 N/A ARG 134.A NE CYS 221.A O no hydrogen 3.083 N/A ARG 134.A NH2 CYS 221.A O no hydrogen 2.841 N/A THR 136.A N SER 133.A O no hydrogen 3.178 N/A THR 136.A OG1 SER 133.A O no hydrogen 2.726 N/A THR 139.A N ASP 143.A OD2 no hydrogen 2.770 N/A THR 139.A OG1 ASP 143.A OD2 no hydrogen 3.082 N/A ASP 143.A N GLY 140.A O no hydrogen 3.171 N/A LYS 145.A N ASP 143.A OD1 no hydrogen 2.919 N/A PHE 146.A N ASP 143.A O no hydrogen 2.945 N/A GLN 147.A N ASP 143.A O no hydrogen 3.046 N/A ARG 148.A N LYS 144.A O no hydrogen 2.831 N/A ARG 148.A NE ASP 151.A OD2 no hydrogen 2.716 N/A ARG 148.A NH2 ASP 151.A OD1 no hydrogen 3.366 N/A ARG 148.A NH2 ASP 151.A OD2 no hydrogen 3.346 N/A HIS 150.A ND1 TYR 176.A OH no hydrogen 3.315 N/A ASP 151.A N ARG 148.A O no hydrogen 3.137 N/A TYR 152.A N PRO 149.A O no hydrogen 3.392 N/A ARG 157.A N ASP 202.A OD2 no hydrogen 2.809 N/A ARG 157.A NE ASP 202.A OD2 no hydrogen 3.087 N/A ARG 157.A NH1 GLY 199.A O no hydrogen 2.944 N/A ARG 157.A NH2 GLY 199.A O no hydrogen 2.770 N/A ARG 157.A NH2 ASP 202.A OD1 no hydrogen 2.788 N/A GLY 159.A N ALA 203.A O no hydrogen 3.256 N/A THR 160.A OG1 VAL 161.A O no hydrogen 3.506 N/A THR 160.A OG1 ILE 205.A O no hydrogen 2.701 N/A ASN 163.A N GLU 167.A OE1 no hydrogen 2.801 N/A ARG 168.A N GLY 164.A O no hydrogen 3.287 N/A ARG 168.A NE ARG 168.A O no hydrogen 3.247 N/A ASN 169.A N SER 165.A O no hydrogen 3.068 N/A ILE 170.A N THR 166.A O no hydrogen 3.060 N/A ARG 171.A N GLU 167.A O no hydrogen 2.832 N/A ARG 171.A NH1 HIS 178.A NE2 no hydrogen 3.425 N/A ASN 172.A N ARG 168.A O no hydrogen 3.029 N/A ASN 173.A N ASN 169.A O no hydrogen 2.928 N/A ASN 173.A ND2 ASN 169.A OD1 no hydrogen 2.854 N/A TYR 174.A N ILE 170.A O no hydrogen 2.785 N/A HIS 178.A N TYR 174.A O no hydrogen 2.999 N/A GLN 179.A N PRO 175.A O no hydrogen 3.171 N/A GLN 179.A NE2 TYR 176.A O no hydrogen 3.023 N/A TYR 180.A N TYR 176.A O no hydrogen 3.056 N/A TYR 180.A OH PHE 156.A O no hydrogen 2.668 N/A MET 181.A N MET 177.A O no hydrogen 2.968 N/A THR 182.A OG1 GLN 179.A O no hydrogen 3.257 N/A LYS 183.A NZ TYR 180.A O no hydrogen 2.846 N/A PHE 184.A N MET 181.A O no hydrogen 2.760 N/A ASN 185.A N THR 182.A O no hydrogen 3.100 N/A GLN 186.A N THR 160.A O no hydrogen 2.969 N/A GLN 186.A NE2 PHE 184.A O no hydrogen 2.778 N/A ALA 192.A N GLY 188.A O no hydrogen 3.104 N/A LEU 193.A N VAL 189.A O no hydrogen 2.926 N/A VAL 194.A N GLU 190.A O no hydrogen 3.217 N/A SER 195.A N ASP 191.A O no hydrogen 2.991 N/A SER 195.A OG.A GLN 186.A OE1 no hydrogen 3.137 N/A SER 195.A OG.A ASP 191.A O no hydrogen 3.110 N/A LEU 196.A N ALA 192.A O no hydrogen 2.984 N/A LYS 197.A N LEU 193.A O no hydrogen 2.935 N/A LYS 197.A NZ ASP 218.A OD1 no hydrogen 2.932 N/A THR 198.A N VAL 194.A O no hydrogen 2.989 N/A THR 198.A OG1 VAL 194.A O no hydrogen 2.864 N/A GLY 199.A N LEU 196.A O no hydrogen 3.148 N/A LYS 200.A N SER 195.A O no hydrogen 2.778 N/A LEU 201.A N SER 195.A O no hydrogen 3.041 N/A ASP 202.A N ARG 157.A O no hydrogen 2.739 N/A ALA 203.A N ARG 157.A O no hydrogen 3.170 N/A PHE 204.A N MET 131.A O no hydrogen 2.888 N/A ILE 205.A N GLY 159.A O no hydrogen 2.920 N/A TYR 206.A N SER 129.A O no hydrogen 3.159 N/A TYR 206.A OH GLU 10.A OE2 no hydrogen 2.675 N/A ALA 208.A N GLY 127.A O no hydrogen 2.884 N/A ALA 209.A N THR 126.A OG1 no hydrogen 3.147 N/A VAL 210.A N ASP 207.A OD2 no hydrogen 2.957 N/A LEU 211.A N ASP 207.A O no hydrogen 2.994 N/A ASN 212.A N ALA 208.A O no hydrogen 2.892 N/A ASN 212.A ND2 ALA 208.A O no hydrogen 2.797 N/A TYR 213.A N ALA 209.A O no hydrogen 3.110 N/A LYS 214.A N VAL 210.A O no hydrogen 2.823 N/A ALA 215.A N LEU 211.A O no hydrogen 2.850 N/A GLY 216.A N ASN 212.A O no hydrogen 3.110 N/A ARG 217.A N LYS 214.A O no hydrogen 3.188 N/A ARG 217.A NE THR 273.A O no hydrogen 2.846 N/A ARG 217.A NH2 THR 273.A O no hydrogen 2.815 N/A ASP 218.A N ALA 215.A O no hydrogen 3.423 N/A CYS 221.A N ASP 218.A O no hydrogen 3.065 N/A LEU 223.A N ASP 218.A OD2 no hydrogen 2.806 N/A VAL 224.A N VAL 132.A O no hydrogen 2.869 N/A THR 225.A OG1 ASN 212.A OD1 no hydrogen 3.014 N/A ILE 226.A N VAL 130.A O no hydrogen 2.853 N/A GLY 229.A N THR 225.A O no hydrogen 3.493 N/A TYR 230.A N ILE 226.A O no hydrogen 3.023 N/A PHE 232.A N ILE 128.A O no hydrogen 2.793 N/A THR 235.A N THR 126.A O no hydrogen 2.810 N/A THR 235.A OG1 ILE 109.A O no hydrogen 2.586 N/A TYR 237.A N VAL 124.A O no hydrogen 2.893 N/A TYR 237.A OH ASP 207.A OD2 no hydrogen 2.609 N/A GLY 238.A N LEU 107.A O no hydrogen 3.106 N/A ILE 239.A N SER 120.A OG no hydrogen 2.948 N/A ALA 240.A N ALA 103.A O no hydrogen 3.128 N/A LEU 241.A N ASP 118.A O no hydrogen 2.749 N/A GLN 242.A NE2 ALA 100.A O no hydrogen 2.888 N/A LYS 243.A NZ SER 114.A O no hydrogen 2.809 N/A LYS 243.A NZ VAL 117.A O no hydrogen 3.345 N/A LYS 243.A NZ ASP 118.A OD1 no hydrogen 3.263 N/A GLY 244.A N ASP 118.A OD2 no hydrogen 3.440 N/A SER 245.A N GLN 242.A O no hydrogen 2.940 N/A TRP 247.A N SER 245.A OG no hydrogen 3.093 N/A LYS 248.A NZ ASP 252.A OD2 no hydrogen 2.989 N/A ILE 251.A N TRP 247.A O no hydrogen 3.070 N/A ASP 252.A N LYS 248.A O no hydrogen 2.935 N/A LEU 253.A N ARG 249.A O no hydrogen 3.103 N/A ALA 254.A N GLN 250.A O no hydrogen 2.940 N/A LEU 255.A N ILE 251.A O no hydrogen 2.917 N/A LEU 256.A N ASP 252.A O no hydrogen 3.063 N/A GLN 257.A N LEU 253.A O no hydrogen 2.926 N/A PHE 258.A N ALA 254.A O no hydrogen 2.846 N/A VAL 259.A N LEU 255.A O no hydrogen 3.019 N/A GLY 260.A N LEU 256.A O no hydrogen 2.942 N/A ASP 261.A N GLN 257.A O no hydrogen 2.886 N/A GLY 262.A N VAL 259.A O no hydrogen 3.358 N/A GLU 263.A N ASP 261.A OD1 no hydrogen 3.182 N/A MET 264.A N PHE 258.A O no hydrogen 3.056 N/A GLU 266.A N GLY 262.A O no hydrogen 3.082 N/A LEU 267.A N GLU 263.A O no hydrogen 3.182 N/A GLU 268.A N MET 264.A O no hydrogen 3.047 N/A THR 269.A N GLU 265.A O no hydrogen 3.048 N/A THR 269.A OG1 GLU 265.A O no hydrogen 3.134 N/A LEU 270.A N GLU 266.A O no hydrogen 3.006 N/A TRP 271.A N LEU 267.A O no hydrogen 2.902 N/A TRP 271.A NE1 ASP 57.A OD2 no hydrogen 2.750 N/A LEU 272.A N GLU 268.A O no hydrogen 2.746 N/A THR 273.A OG1 THR 269.A O no hydrogen 3.007 N/A CYS 276.A N GLY 216.A O no hydrogen 3.034 N/A CYS 276.A SG GLY 216.A O no hydrogen 3.765 N/A CYS 276.A SG ASP 218.A O no hydrogen 3.388 N/A