Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5hto_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 1.A NZ ASP 27.A OD1 no hydrogen 2.932 N/A LYS 1.A NZ ASN 55.A O no hydrogen 2.964 N/A LYS 3.A N ASP 71.A OD2 no hydrogen 2.717 N/A LYS 3.A NZ ASP 66.A O no hydrogen 2.982 N/A LYS 3.A NZ LYS 68.A O no hydrogen 2.707 N/A ILE 4.A N ASP 27.A O no hydrogen 2.879 N/A VAL 5.A N VAL 72.A O no hydrogen 2.859 N/A LEU 6.A N VAL 29.A O no hydrogen 2.802 N/A VAL 7.A N ILE 74.A O no hydrogen 2.860 N/A GLY 8.A N PHE 31.A O no hydrogen 2.854 N/A SER 9.A N ASP 32.A OD2 no hydrogen 2.814 N/A SER 9.A OG PHE 31.A O no hydrogen 2.824 N/A GLY 14.A N GLY 10.A O no hydrogen 2.937 N/A VAL 15.A N MET 11.A O no hydrogen 3.043 N/A MET 16.A N ILE 12.A O no hydrogen 2.917 N/A ALA 17.A N GLY 13.A O no hydrogen 2.936 N/A THR 18.A N GLY 14.A O no hydrogen 2.987 N/A THR 18.A OG1 GLY 14.A O no hydrogen 3.004 N/A LEU 19.A N VAL 15.A O no hydrogen 2.921 N/A ILE 20.A N MET 16.A O no hydrogen 2.900 N/A VAL 21.A N ALA 17.A O no hydrogen 3.005 N/A GLN 22.A N THR 18.A O no hydrogen 2.956 N/A LYS 23.A N LEU 19.A O no hydrogen 3.025 N/A ASN 24.A N VAL 21.A O no hydrogen 3.081 N/A LEU 25.A N ILE 20.A O no hydrogen 3.072 N/A ASP 27.A N PRO 2.A O no hydrogen 2.891 N/A VAL 28.A N LYS 57.A O no hydrogen 2.742 N/A VAL 29.A N ILE 4.A O no hydrogen 2.938 N/A MET 30.A N THR 59.A O no hydrogen 2.810 N/A PHE 31.A N LEU 6.A O no hydrogen 2.850 N/A ASP 32.A N SER 61.A O no hydrogen 3.131 N/A VAL 34.A N ASP 32.A OD1 no hydrogen 2.928 N/A ASN 36.A N ASN 62.A OD1 no hydrogen 3.434 N/A MET 37.A N LYS 35.A O no hydrogen 2.794 N/A GLN 39.A N GLN 39.A OE1 no hydrogen 2.801 N/A GLN 39.A NE2 ASN 62.A OD1 no hydrogen 3.175 N/A GLY 40.A N ASN 36.A O no hydrogen 3.046 N/A LYS 41.A N MET 37.A O no hydrogen 2.948 N/A LYS 41.A NZ SER 9.A O no hydrogen 2.770 N/A LYS 41.A NZ GLY 10.A O no hydrogen 3.020 N/A ALA 42.A N PRO 38.A O no hydrogen 2.894 N/A LEU 43.A N GLN 39.A O no hydrogen 2.935 N/A ASP 44.A N GLY 40.A O no hydrogen 3.027 N/A THR 45.A N LYS 41.A O no hydrogen 2.899 N/A THR 45.A OG1 LYS 41.A O no hydrogen 2.734 N/A SER 46.A N ALA 42.A O no hydrogen 2.873 N/A SER 46.A OG LEU 43.A O no hydrogen 2.660 N/A HIS 47.A N ASP 44.A O no hydrogen 3.333 N/A SER 48.A N THR 45.A O no hydrogen 3.030 N/A SER 48.A OG THR 45.A O no hydrogen 2.646 N/A ASN 49.A N SER 46.A O no hydrogen 3.192 N/A ASN 49.A ND2 SER 46.A O no hydrogen 2.953 N/A ASN 49.A ND2 CYS 56.A O no hydrogen 2.794 N/A VAL 50.A N HIS 47.A O no hydrogen 3.145 N/A ALA 52.A N SER 48.A O no hydrogen 2.940 N/A TYR 53.A N VAL 50.A O no hydrogen 3.222 N/A SER 54.A N ASN 49.A O no hydrogen 2.959 N/A SER 54.A OG VAL 21.A O no hydrogen 2.664 N/A SER 54.A OG ALA 52.A O no hydrogen 3.491 N/A ASN 55.A N ASN 24.A OD1 no hydrogen 2.965 N/A CYS 56.A N ASN 49.A OD1 no hydrogen 2.845 N/A CYS 56.A SG ASN 24.A OD1 no hydrogen 3.316 N/A CYS 56.A SG GLY 26.A O no hydrogen 3.106 N/A LYS 57.A N ASP 27.A OD1 no hydrogen 2.843 N/A THR 59.A N VAL 28.A O no hydrogen 2.956 N/A SER 61.A N MET 30.A O no hydrogen 2.894 N/A SER 61.A OG SER 63.A O no hydrogen 2.984 N/A SER 61.A OG ASP 66.A OD2 no hydrogen 2.578 N/A ASN 62.A ND2 ASP 32.A O no hydrogen 2.911 N/A ASN 62.A ND2 VAL 34.A O no hydrogen 2.857 N/A SER 63.A N SER 61.A OG no hydrogen 2.904 N/A ASP 65.A N SER 63.A OG no hydrogen 3.122 N/A ASP 66.A N SER 63.A O no hydrogen 3.143 N/A LEU 67.A N TYR 64.A O no hydrogen 2.908 N/A LYS 68.A N ASP 65.A O no hydrogen 3.201 N/A ALA 70.A N LEU 67.A O no hydrogen 3.102 N/A ASP 71.A N LYS 3.A O no hydrogen 2.729 N/A VAL 72.A N LYS 3.A O no hydrogen 3.068 N/A VAL 73.A N PHE 107.A O no hydrogen 2.911 N/A ILE 74.A N VAL 5.A O no hydrogen 2.910 N/A VAL 75.A N ILE 109.A O no hydrogen 2.873 N/A THR 76.A N VAL 7.A O no hydrogen 2.926 N/A ALA 77.A N VAL 7.A O no hydrogen 3.091 N/A PHE 79.A N ASN 88.A OD1 no hydrogen 2.797 N/A ASN 88.A N LEU 84.A O no hydrogen 2.937 N/A ASN 88.A ND2 PHE 79.A O no hydrogen 3.137 N/A ASN 88.A ND2 ASN 113.A O no hydrogen 3.420 N/A ASN 89.A N LEU 85.A O no hydrogen 2.910 N/A LYS 90.A N PRO 86.A O no hydrogen 2.968 N/A ILE 91.A N LEU 87.A O no hydrogen 3.021 N/A MET 92.A N ASN 88.A O no hydrogen 2.886 N/A ILE 93.A N ASN 89.A O no hydrogen 2.915 N/A GLU 94.A N LYS 90.A O no hydrogen 3.013 N/A ILE 95.A N ILE 91.A O no hydrogen 2.941 N/A GLY 96.A N MET 92.A O no hydrogen 2.888 N/A GLY 97.A N ILE 93.A O no hydrogen 2.966 N/A HIS 98.A N GLU 94.A O no hydrogen 3.074 N/A ILE 99.A N ILE 95.A O no hydrogen 2.880 N/A LYS 100.A N GLY 96.A O no hydrogen 2.905 N/A ASN 101.A N GLY 97.A O no hydrogen 2.995 N/A LEU 102.A N HIS 98.A O no hydrogen 2.875 N/A CYS 103.A N ILE 99.A O no hydrogen 2.996 N/A ALA 106.A N CYS 103.A O no hydrogen 3.129 N/A PHE 107.A N ASP 71.A O no hydrogen 3.001 N/A ILE 108.A N LYS 132.A O no hydrogen 2.761 N/A ILE 109.A N VAL 73.A O no hydrogen 2.911 N/A VAL 110.A N ILE 134.A O no hydrogen 2.817 N/A VAL 111.A N VAL 75.A O no hydrogen 2.856 N/A THR 112.A N VAL 75.A O no hydrogen 3.393 N/A THR 112.A OG1 VAL 75.A O no hydrogen 3.562 N/A THR 112.A OG1 ALA 77.A O no hydrogen 2.525 N/A VAL 115.A N ASN 113.A OD1 no hydrogen 3.045 N/A VAL 117.A N PRO 114.A O no hydrogen 3.143 N/A MET 118.A N PRO 114.A O no hydrogen 3.088 N/A VAL 119.A N VAL 115.A O no hydrogen 2.879 N/A GLN 120.A NE2 ASN 258.A O no hydrogen 2.959 N/A LEU 121.A N VAL 117.A O no hydrogen 2.975 N/A LEU 122.A N MET 118.A O no hydrogen 2.916 N/A PHE 123.A N VAL 119.A O no hydrogen 2.925 N/A GLU 124.A N GLN 120.A O no hydrogen 2.904 N/A HIS 125.A N LEU 121.A O no hydrogen 2.949 N/A SER 126.A N LEU 122.A O no hydrogen 2.901 N/A SER 126.A OG LEU 122.A O no hydrogen 2.766 N/A SER 126.A OG PHE 123.A O no hydrogen 3.407 N/A GLY 127.A N PHE 123.A O no hydrogen 3.226 N/A VAL 128.A N SER 126.A OG no hydrogen 3.351 N/A LYS 130.A NZ GLU 251.A OE2 no hydrogen 2.883 N/A LYS 132.A N PRO 129.A O no hydrogen 2.941 N/A LYS 132.A NZ ASN 105.A O no hydrogen 2.909 N/A ILE 134.A N ILE 108.A O no hydrogen 2.960 N/A GLY 135.A N SER 247.A O no hydrogen 2.969 N/A LEU 136.A N VAL 110.A O no hydrogen 2.911 N/A ASP 141.A N GLY 137.A O no hydrogen 3.177 N/A THR 142.A N GLY 138.A O no hydrogen 2.890 N/A THR 142.A OG1 GLY 138.A O no hydrogen 2.856 N/A THR 142.A OG1 VAL 139.A O no hydrogen 3.342 N/A SER 143.A N VAL 139.A O no hydrogen 2.968 N/A SER 143.A OG LEU 140.A O no hydrogen 2.546 N/A ARG 144.A N LEU 140.A O no hydrogen 3.085 N/A LEU 145.A N ASP 141.A O no hydrogen 3.069 N/A LYS 146.A N THR 142.A O no hydrogen 2.869 N/A LYS 146.A NZ THR 142.A OG1 no hydrogen 3.245 N/A TYR 147.A N SER 143.A O no hydrogen 2.962 N/A TYR 148.A N ARG 144.A O no hydrogen 2.983 N/A TYR 148.A OH THR 210.A OG1 no hydrogen 2.992 N/A ILE 149.A N LEU 145.A O no hydrogen 3.017 N/A SER 150.A N LYS 146.A O no hydrogen 2.927 N/A SER 150.A OG LYS 146.A O no hydrogen 3.483 N/A SER 150.A OG TYR 147.A O no hydrogen 2.694 N/A GLN 151.A N TYR 147.A O no hydrogen 2.979 N/A GLN 151.A NE2 SER 150.A OG no hydrogen 2.994 N/A LYS 152.A N TYR 148.A O no hydrogen 3.094 N/A LEU 153.A N ILE 149.A O no hydrogen 2.951 N/A VAL 155.A N SER 150.A O no hydrogen 3.158 N/A ARG 158.A NH1 GLU 231.A OE2 no hydrogen 3.085 N/A ARG 158.A NH2 GLU 231.A OE2 no hydrogen 2.685 N/A ASP 159.A N CYS 156.A O no hydrogen 2.863 N/A VAL 160.A N PRO 157.A O no hydrogen 3.172 N/A ASN 161.A N THR 180.A O no hydrogen 2.910 N/A ALA 162.A N ASN 161.A OD1 no hydrogen 3.035 N/A VAL 165.A N VAL 173.A O no hydrogen 2.965 N/A GLY 166.A N GLY 262.A O no hydrogen 2.945 N/A ALA 167.A N VAL 165.A O no hydrogen 3.143 N/A HIS 168.A N ASP 116.A OD2 no hydrogen 2.857 N/A HIS 168.A ND1 ASP 141.A OD2 no hydrogen 2.600 N/A MET 172.A N GLY 169.A O no hydrogen 2.905 N/A VAL 173.A N VAL 165.A O no hydrogen 2.873 N/A LEU 175.A N LEU 163.A O no hydrogen 3.335 N/A LYS 176.A NZ ASP 197.A OD1 no hydrogen 2.591 N/A ARG 177.A NE GLU 284.A OE1 no hydrogen 2.940 N/A ARG 177.A NH2 GLN 279.A O no hydrogen 3.224 N/A ARG 177.A NH2 GLU 284.A OE2 no hydrogen 2.874 N/A TYR 178.A N LEU 175.A O no hydrogen 3.014 N/A ILE 179.A N LYS 176.A O no hydrogen 3.313 N/A THR 180.A N ASN 161.A O no hydrogen 2.882 N/A VAL 181.A N ILE 184.A O no hydrogen 2.739 N/A GLY 182.A N ASP 159.A O no hydrogen 2.796 N/A ILE 184.A N VAL 181.A O no hydrogen 2.949 N/A LEU 186.A N ILE 179.A O no hydrogen 3.013 N/A GLN 187.A NE2 ASN 191.A OD1 no hydrogen 2.936 N/A GLU 188.A N PRO 185.A O no hydrogen 3.025 N/A ILE 190.A N LEU 186.A O no hydrogen 2.996 N/A ASN 191.A N GLN 187.A O no hydrogen 2.846 N/A ASN 192.A N GLU 188.A O no hydrogen 3.129 N/A LYS 193.A N ILE 190.A O no hydrogen 2.885 N/A LYS 194.A N PHE 189.A O no hydrogen 2.849 N/A GLU 199.A N THR 196.A OG1 no hydrogen 2.950 N/A VAL 200.A N THR 196.A O no hydrogen 3.025 N/A GLU 201.A N ASP 197.A O no hydrogen 2.943 N/A GLY 202.A N GLU 198.A O no hydrogen 2.933 N/A ILE 203.A N GLU 199.A O no hydrogen 2.909 N/A PHE 204.A N VAL 200.A O no hydrogen 2.907 N/A ASP 205.A N GLU 201.A O no hydrogen 2.996 N/A ARG 206.A N GLY 202.A O no hydrogen 2.923 N/A ARG 206.A NE GLU 213.A OE1 no hydrogen 2.991 N/A ARG 206.A NH2 GLU 213.A OE2 no hydrogen 2.981 N/A THR 207.A N ILE 203.A O no hydrogen 2.877 N/A THR 207.A OG1 ILE 203.A O no hydrogen 2.831 N/A VAL 208.A N PHE 204.A O no hydrogen 2.965 N/A ASN 209.A N ASP 205.A O no hydrogen 3.078 N/A ASN 209.A ND2 ASP 205.A O no hydrogen 3.049 N/A THR 210.A N THR 207.A O no hydrogen 3.374 N/A THR 210.A OG1 TYR 148.A OH no hydrogen 2.992 N/A THR 210.A OG1 ARG 206.A O no hydrogen 2.697 N/A THR 210.A OG1 THR 207.A O no hydrogen 3.555 N/A GLU 213.A N ASN 209.A O no hydrogen 2.883 N/A ILE 214.A N THR 210.A O no hydrogen 2.922 N/A VAL 215.A N ALA 211.A O no hydrogen 2.945 N/A ASN 216.A N LEU 212.A O no hydrogen 2.867 N/A LEU 217.A N GLU 213.A O no hydrogen 3.159 N/A LEU 217.A N ILE 214.A O no hydrogen 3.012 N/A LEU 218.A N VAL 215.A O no hydrogen 2.869 N/A ALA 219.A N ILE 214.A O no hydrogen 3.127 N/A ALA 226.A N TYR 222.A O no hydrogen 3.083 N/A ALA 227.A N VAL 223.A O no hydrogen 2.950 N/A ALA 228.A N ALA 224.A O no hydrogen 2.909 N/A ILE 229.A N PRO 225.A O no hydrogen 2.983 N/A ILE 230.A N ALA 226.A O no hydrogen 2.948 N/A GLU 231.A N ALA 227.A O no hydrogen 2.927 N/A MET 232.A N ALA 228.A O no hydrogen 3.045 N/A ALA 233.A N ILE 229.A O no hydrogen 2.905 N/A GLU 234.A N ILE 230.A O no hydrogen 2.856 N/A SER 235.A N GLU 231.A O no hydrogen 2.998 N/A SER 235.A OG ILE 267.A O no hydrogen 2.660 N/A TYR 236.A N MET 232.A O no hydrogen 3.062 N/A LEU 237.A N ALA 233.A O no hydrogen 2.878 N/A LYS 238.A N GLU 234.A O no hydrogen 2.936 N/A LYS 238.A NZ GLU 234.A OE2 no hydrogen 3.172 N/A ASP 239.A N TYR 236.A O no hydrogen 3.212 N/A ILE 240.A N SER 235.A O no hydrogen 3.055 N/A LYS 242.A N SER 235.A OG no hydrogen 3.253 N/A LYS 242.A NZ GLU 231.A OE2 no hydrogen 2.850 N/A LEU 244.A N LEU 265.A O no hydrogen 2.868 N/A CYS 246.A N THR 263.A O no hydrogen 3.064 N/A CYS 246.A SG LEU 244.A O no hydrogen 3.760 N/A SER 247.A N GLY 135.A O no hydrogen 3.046 N/A SER 247.A OG ASP 116.A OD1 no hydrogen 2.675 N/A THR 248.A N GLY 261.A O no hydrogen 2.985 N/A LEU 250.A N ILE 259.A O no hydrogen 2.876 N/A GLU 251.A N GLN 253.A OE1 no hydrogen 2.629 N/A GLY 252.A N HIS 256.A O no hydrogen 2.663 N/A GLN 253.A N GLN 253.A OE1 no hydrogen 2.829 N/A TYR 254.A N GLU 277.A OE2 no hydrogen 2.833 N/A TYR 254.A OH THR 263.A OG1 no hydrogen 2.681 N/A GLY 255.A N GLY 252.A O no hydrogen 3.003 N/A HIS 256.A N GLN 253.A O no hydrogen 3.016 N/A HIS 256.A NE2 ASP 289.A OD1 no hydrogen 2.640 N/A GLY 261.A N THR 248.A O no hydrogen 2.951 N/A GLY 262.A N GLY 166.A O no hydrogen 3.116 N/A THR 263.A N CYS 246.A O no hydrogen 2.982 N/A THR 263.A OG1 TYR 254.A OH no hydrogen 2.681 N/A THR 263.A OG1 ILE 276.A O no hydrogen 2.734 N/A LEU 265.A N LEU 244.A O no hydrogen 2.924 N/A VAL 266.A N GLN 274.A O no hydrogen 2.917 N/A ILE 267.A N LYS 242.A O no hydrogen 3.009 N/A GLY 268.A N GLY 271.A O no hydrogen 2.988 N/A GLY 269.A N ASP 239.A OD1 no hydrogen 2.763 N/A THR 270.A N GLU 273.A OE1 no hydrogen 3.318 N/A THR 270.A OG1 GLU 273.A OE1 no hydrogen 3.074 N/A GLY 271.A N GLY 268.A O no hydrogen 2.936 N/A VAL 272.A N ASN 131.A O no hydrogen 2.828 N/A GLU 273.A N VAL 266.A O no hydrogen 2.856 N/A ILE 276.A N PRO 264.A O no hydrogen 2.898 N/A LEU 278.A N TYR 254.A OH no hydrogen 2.900 N/A ASN 281.A N GLU 284.A OE2 no hydrogen 2.864 N/A GLU 284.A N ASN 281.A OD1 no hydrogen 2.941 N/A LYS 285.A N ASN 281.A O no hydrogen 2.946 N/A THR 286.A N ALA 282.A O no hydrogen 2.923 N/A THR 286.A OG1 ALA 282.A O no hydrogen 3.064 N/A LYS 287.A N GLU 283.A O no hydrogen 3.017 N/A PHE 288.A N GLU 284.A O no hydrogen 2.918 N/A ASP 289.A N LYS 285.A O no hydrogen 2.882 N/A GLU 290.A N THR 286.A O no hydrogen 2.968 N/A ALA 291.A N LYS 287.A O no hydrogen 2.991 N/A VAL 292.A N PHE 288.A O no hydrogen 2.975 N/A ALA 293.A N ASP 289.A O no hydrogen 2.886 N/A GLU 294.A N GLU 290.A O no hydrogen 2.997 N/A THR 295.A N ALA 291.A O no hydrogen 3.011 N/A THR 295.A OG1 ALA 291.A O no hydrogen 3.393 N/A LYS 296.A N VAL 292.A O no hydrogen 2.898 N/A ARG 297.A N ALA 293.A O no hydrogen 2.900 N/A ARG 297.A NE GLU 294.A OE1 no hydrogen 3.298 N/A ARG 297.A NE GLU 294.A OE2 no hydrogen 2.943 N/A ARG 297.A NH2 GLU 294.A OE1 no hydrogen 2.850 N/A MET 298.A N GLU 294.A O no hydrogen 2.967 N/A LYS 299.A N THR 295.A O no hydrogen 2.909 N/A LYS 299.A NZ GLN 120.A OE1 no hydrogen 2.956 N/A ALA 300.A N LYS 296.A O no hydrogen 2.989 N/A ALA 300.A N ARG 297.A O no hydrogen 3.237 N/A LEU 301.A N MET 298.A O no hydrogen 2.943 N/A