Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5hx7_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 1.A NZ ASN 21.A O no hydrogen 2.832 N/A ASN 3.A N ASP 52.A OD2 no hydrogen 2.862 N/A VAL 4.A N GLU 24.A O no hydrogen 2.848 N/A VAL 5.A N LEU 53.A O no hydrogen 2.858 N/A ALA 6.A N HIS 26.A O no hydrogen 2.906 N/A THR 7.A N PHE 55.A O no hydrogen 3.094 N/A THR 7.A OG1 GLU 62.A OE2 no hydrogen 2.687 N/A SER 9.A OG SER 248.A OG no hydrogen 3.286 N/A ALA 12.A N TYR 8.A O no hydrogen 2.967 N/A ASP 13.A N SER 9.A O no hydrogen 3.025 N/A ILE 14.A N ILE 10.A O no hydrogen 3.117 N/A VAL 15.A N LEU 11.A O no hydrogen 2.837 N/A LYS 16.A N ALA 12.A O no hydrogen 2.883 N/A LYS 16.A NZ GLY 20.A O no hydrogen 2.710 N/A ASN 17.A N ASP 13.A O no hydrogen 3.145 N/A ASN 17.A ND2 ASP 13.A O no hydrogen 2.851 N/A VAL 18.A N VAL 15.A O no hydrogen 2.981 N/A GLY 19.A N VAL 15.A O no hydrogen 2.802 N/A GLY 20.A N LYS 16.A O no hydrogen 2.833 N/A LYS 22.A N GLY 19.A O no hydrogen 3.121 N/A GLU 24.A N LEU 2.A O no hydrogen 2.828 N/A HIS 26.A N VAL 4.A O no hydrogen 2.987 N/A ILE 28.A N ALA 6.A O no hydrogen 2.989 N/A VAL 29.A N THR 7.A O no hydrogen 2.869 N/A GLY 32.A N SER 248.A OG no hydrogen 2.877 N/A VAL 33.A N PRO 30.A O no hydrogen 3.215 N/A HIS 36.A N ASP 34.A OD1 no hydrogen 3.067 N/A HIS 36.A ND1 LEU 61.A O no hydrogen 2.807 N/A GLU 37.A N ASP 34.A OD2 no hydrogen 3.266 N/A LEU 41.A N ASN 44.A OD1 no hydrogen 2.850 N/A ASN 44.A ND2 HIS 26.A NE2 no hydrogen 2.981 N/A ILE 45.A N LEU 41.A O no hydrogen 3.126 N/A GLN 46.A N PRO 42.A O no hydrogen 3.028 N/A SER 47.A N ALA 43.A O no hydrogen 2.956 N/A SER 47.A OG ALA 43.A O no hydrogen 2.788 N/A ALA 48.A N ASN 44.A O no hydrogen 2.880 N/A ALA 49.A N ILE 45.A O no hydrogen 2.938 N/A ASP 50.A N GLN 46.A O no hydrogen 3.007 N/A ALA 51.A N ALA 48.A O no hydrogen 3.395 N/A ASP 52.A N ASN 3.A O no hydrogen 2.772 N/A LEU 53.A N ASN 3.A O no hydrogen 3.226 N/A ILE 54.A N GLN 83.A O no hydrogen 2.864 N/A PHE 55.A N VAL 5.A O no hydrogen 2.741 N/A TYR 56.A N VAL 85.A O no hydrogen 3.074 N/A ASN 57.A N GLU 62.A OE2 no hydrogen 2.797 N/A ASN 57.A ND2 TYR 119.A OH no hydrogen 2.607 N/A GLY 58.A N GLU 62.A OE1 no hydrogen 3.178 N/A LEU 61.A N GLY 58.A O no hydrogen 2.950 N/A GLU 62.A N GLU 62.A OE1 no hydrogen 3.045 N/A THR 63.A N LEU 61.A O no hydrogen 2.840 N/A THR 63.A OG1 ASN 60.A O no hydrogen 2.777 N/A GLY 64.A N HIS 36.A O no hydrogen 2.762 N/A GLY 66.A N THR 63.A O no hydrogen 2.838 N/A TRP 67.A N GLY 64.A O no hydrogen 3.067 N/A TRP 67.A NE1 PRO 35.A O no hydrogen 2.921 N/A PHE 68.A N GLU 62.A O no hydrogen 3.407 N/A ARG 70.A N GLY 66.A O no hydrogen 3.020 N/A ARG 70.A NH2 ASN 65.A O no hydrogen 2.924 N/A GLU 72.A N ASP 69.A O no hydrogen 2.987 N/A THR 73.A N ARG 70.A O no hydrogen 3.073 N/A THR 73.A OG1 ARG 70.A O no hydrogen 3.154 N/A ASP 75.A N GLU 72.A O no hydrogen 3.182 N/A LYS 76.A N LEU 71.A O no hydrogen 2.836 N/A LYS 76.A NZ ALA 48.A O no hydrogen 2.709 N/A LYS 76.A NZ ALA 49.A O no hydrogen 2.833 N/A LYS 76.A NZ ALA 51.A O no hydrogen 3.094 N/A ARG 78.A NE ASP 69.A OD1 no hydrogen 2.663 N/A ARG 78.A NH2 ASP 69.A OD1 no hydrogen 3.466 N/A ARG 78.A NH2 ASP 69.A OD2 no hydrogen 2.738 N/A GLU 79.A N SER 77.A OG no hydrogen 3.006 N/A ASP 80.A N SER 77.A O no hydrogen 3.092 N/A LYS 81.A NZ ARG 78.A O no hydrogen 3.078 N/A GLN 83.A N ASP 80.A O no hydrogen 3.106 N/A VAL 84.A N ASP 80.A O no hydrogen 2.914 N/A VAL 85.A N ILE 54.A O no hydrogen 2.784 N/A LEU 87.A N TYR 56.A O no hydrogen 2.883 N/A SER 88.A N ASN 57.A O no hydrogen 3.380 N/A SER 88.A OG ASN 57.A O no hydrogen 2.674 N/A LYS 89.A N GLU 86.A O no hydrogen 3.351 N/A VAL 91.A N SER 88.A O no hydrogen 2.980 N/A LYS 94.A N TYR 179.A OH no hydrogen 2.883 N/A LEU 96.A N GLU 104.A O no hydrogen 2.981 N/A THR 97.A N GLU 193.A OE1 no hydrogen 2.923 N/A THR 97.A OG1 TYR 190.A OH no hydrogen 3.344 N/A THR 97.A OG1 GLU 193.A OE1 no hydrogen 2.810 N/A LYS 101.A N GLU 98.A O no hydrogen 2.854 N/A LYS 101.A NZ ASN 195.A O no hydrogen 3.136 N/A GLU 104.A N LYS 101.A O no hydrogen 2.953 N/A ASP 106.A N LYS 94.A O no hydrogen 2.723 N/A HIS 108.A N ASP 106.A OD2 no hydrogen 2.908 N/A HIS 108.A ND1 ASP 106.A OD2 no hydrogen 2.896 N/A ALA 109.A N PRO 107.A O no hydrogen 2.746 N/A TRP 110.A NE1 THR 246.A O no hydrogen 2.793 N/A LEU 111.A N HIS 108.A O no hydrogen 3.296 N/A ASP 112.A N ALA 109.A O no hydrogen 3.183 N/A LEU 113.A N TYR 184.A OH no hydrogen 3.146 N/A HIS 114.A N ASP 112.A OD2 no hydrogen 2.727 N/A ASN 115.A N ASP 112.A OD2 no hydrogen 3.243 N/A ASN 115.A ND2 ALA 109.A O no hydrogen 3.107 N/A GLY 116.A N ASP 112.A O no hydrogen 3.054 N/A ILE 117.A N LEU 113.A O no hydrogen 2.938 N/A ILE 118.A N HIS 114.A O no hydrogen 3.194 N/A TYR 119.A N ASN 115.A O no hydrogen 2.827 N/A THR 120.A N GLY 116.A O no hydrogen 2.978 N/A THR 120.A OG1 GLY 116.A O no hydrogen 2.890 N/A GLU 121.A N ILE 117.A O no hydrogen 2.845 N/A ASN 122.A N ILE 118.A O no hydrogen 2.954 N/A ASN 122.A ND2 LEU 87.A O no hydrogen 2.708 N/A ASN 122.A ND2 LYS 89.A O no hydrogen 2.941 N/A VAL 123.A N TYR 119.A O no hydrogen 3.024 N/A ARG 124.A N THR 120.A O no hydrogen 2.941 N/A ARG 124.A NE ASP 125.A OD1 no hydrogen 2.833 N/A ARG 124.A NH2 ASP 125.A OD1 no hydrogen 2.848 N/A ASP 125.A N GLU 121.A O no hydrogen 2.919 N/A ALA 126.A N ASN 122.A O no hydrogen 3.137 N/A LEU 127.A N VAL 123.A O no hydrogen 2.887 N/A VAL 128.A N ARG 124.A O no hydrogen 2.807 N/A LYS 129.A N ASP 125.A O no hydrogen 3.117 N/A ALA 130.A N ALA 126.A O no hydrogen 3.048 N/A ASP 131.A N LEU 127.A O no hydrogen 2.888 N/A ASN 134.A N ASP 131.A O no hydrogen 3.048 N/A ASN 134.A ND2 ASP 131.A OD1 no hydrogen 3.552 N/A ASN 134.A ND2 ASP 131.A OD2 no hydrogen 2.852 N/A ALA 135.A N PRO 132.A O no hydrogen 3.140 N/A TYR 138.A N ASN 134.A O no hydrogen 3.068 N/A TYR 138.A OH ASP 131.A OD2 no hydrogen 2.654 N/A LYS 139.A N ALA 135.A O no hydrogen 2.908 N/A GLU 140.A N ASP 136.A O no hydrogen 2.897 N/A ASN 141.A N PHE 137.A O no hydrogen 3.018 N/A ASN 141.A ND2 VAL 18.A O no hydrogen 2.870 N/A ALA 142.A N TYR 138.A O no hydrogen 2.926 N/A LYS 143.A N LYS 139.A O no hydrogen 2.969 N/A LYS 144.A N GLU 140.A O no hydrogen 3.032 N/A LYS 144.A NZ.A GLU 140.A OE2.B no hydrogen 2.960 N/A TYR 145.A N ASN 141.A O no hydrogen 2.970 N/A ILE 146.A N ALA 142.A O no hydrogen 2.820 N/A ASP 147.A N LYS 143.A O no hydrogen 3.013 N/A LYS 148.A N LYS 144.A O no hydrogen 3.274 N/A LEU 149.A N TYR 145.A O no hydrogen 3.044 N/A ALA 150.A N ILE 146.A O no hydrogen 2.832 N/A THR 151.A N ASP 147.A O no hydrogen 2.996 N/A THR 151.A OG1 ASP 147.A O no hydrogen 2.771 N/A THR 151.A OG1 ASP 147.A OD1 no hydrogen 3.450 N/A LEU 152.A N LYS 148.A O no hydrogen 3.130 N/A ASP 153.A N LEU 149.A O no hydrogen 2.889 N/A LYS 154.A N ALA 150.A O no hydrogen 2.983 N/A GLU 155.A N THR 151.A O no hydrogen 3.175 N/A ALA 156.A N LEU 152.A O no hydrogen 2.943 N/A LYS 157.A N ASP 153.A O no hydrogen 2.876 N/A LYS 157.A NZ ARG 183.A O no hydrogen 3.420 N/A GLN 158.A N LYS 154.A O no hydrogen 3.279 N/A GLN 158.A NE2 GLN 158.A O no hydrogen 2.956 N/A GLN 158.A NE2 ASP 162.A OD2 no hydrogen 3.025 N/A LYS 159.A N GLU 155.A O no hydrogen 3.092 N/A PHE 160.A N ALA 156.A O no hydrogen 2.908 N/A ALA 161.A N LYS 157.A O no hydrogen 2.965 N/A ASP 162.A N GLN 158.A O no hydrogen 3.200 N/A ASP 162.A N LYS 159.A O no hydrogen 3.211 N/A LEU 163.A N PHE 160.A O no hydrogen 3.183 N/A GLN 167.A N PRO 164.A O no hydrogen 2.906 N/A GLN 167.A NE2 LEU 272.A O no hydrogen 2.630 N/A GLN 167.A NE2 LYS 274.A OXT no hydrogen 2.973 N/A LYS 168.A NZ ALA 161.A O no hydrogen 3.021 N/A LYS 168.A NZ GLU 165.A OE1 no hydrogen 3.110 N/A THR 169.A OG1 GLU 214.A OE1 no hydrogen 2.606 N/A LEU 170.A N LYS 187.A O no hydrogen 2.805 N/A THR 172.A N ALA 189.A O no hydrogen 3.165 N/A THR 172.A OG1 GLU 174.A O no hydrogen 2.853 N/A THR 172.A OG1 GLU 222.A OE2 no hydrogen 3.531 N/A SER 173.A N GLU 222.A OE1 no hydrogen 2.860 N/A SER 173.A OG GLU 222.A OE1 no hydrogen 3.138 N/A GLU 174.A N GLU 222.A OE2 no hydrogen 2.654 N/A LYS 178.A NZ ASP 106.A OD1 no hydrogen 2.715 N/A LYS 178.A NZ GLY 175.A O no hydrogen 2.876 N/A LYS 178.A NZ GLU 193.A OE1 no hydrogen 3.156 N/A LYS 178.A NZ GLU 193.A OE2 no hydrogen 2.889 N/A TYR 179.A OH ASP 106.A O no hydrogen 2.679 N/A ALA 181.A N PHE 177.A O no hydrogen 2.848 N/A ALA 182.A N LYS 178.A O no hydrogen 3.124 N/A ARG 183.A N TYR 179.A O no hydrogen 2.950 N/A ARG 183.A NE ASP 153.A OD1 no hydrogen 2.993 N/A ARG 183.A NH2 ASP 153.A OD2 no hydrogen 2.639 N/A TYR 184.A N PHE 180.A O no hydrogen 2.996 N/A TYR 184.A OH ASP 153.A OD1 no hydrogen 2.717 N/A GLY 185.A N ALA 181.A O no hydrogen 2.951 N/A LEU 186.A N ALA 181.A O no hydrogen 3.015 N/A LYS 187.A N LYS 168.A O no hydrogen 2.772 N/A LYS 187.A NZ GLU 214.A OE2 no hydrogen 2.630 N/A ALA 189.A N LEU 170.A O no hydrogen 2.819 N/A TYR 190.A OH THR 97.A OG1 no hydrogen 3.344 N/A ILE 191.A N THR 172.A O no hydrogen 3.287 N/A ILE 191.A N SER 173.A O no hydrogen 2.964 N/A TRP 192.A N SER 173.A O no hydrogen 2.944 N/A TRP 192.A NE1 GLU 174.A OE2 no hydrogen 2.826 N/A ILE 194.A N GLU 193.A OE2 no hydrogen 2.721 N/A ASN 195.A ND2 GLU 104.A OE2 no hydrogen 3.368 N/A THR 196.A N GLU 193.A O no hydrogen 3.163 N/A THR 196.A OG1 GLU 98.A OE1 no hydrogen 3.360 N/A THR 196.A OG1 GLU 98.A OE2 no hydrogen 2.545 N/A THR 201.A N GLN 204.A OE1 no hydrogen 2.837 N/A GLN 204.A N THR 201.A OG1 no hydrogen 3.103 N/A GLN 204.A NE2 SER 198.A O no hydrogen 2.972 N/A GLN 206.A N ASP 203.A O no hydrogen 3.018 N/A GLN 206.A NE2.B TYR 190.A O no hydrogen 3.580 N/A GLN 206.A NE2.B ILE 191.A O no hydrogen 3.568 N/A ILE 207.A N GLN 204.A O no hydrogen 3.090 N/A GLY 209.A N LYS 205.A O no hydrogen 3.068 N/A ILE 210.A N GLN 206.A O no hydrogen 3.135 N/A VAL 211.A N ILE 207.A O no hydrogen 2.921 N/A GLU 212.A N VAL 208.A O no hydrogen 2.917 N/A LYS 213.A N GLY 209.A O no hydrogen 2.830 N/A GLU 214.A N ILE 210.A O no hydrogen 2.890 N/A LYS 215.A N GLU 212.A O no hydrogen 3.398 N/A VAL 216.A N VAL 211.A O no hydrogen 3.175 N/A ASN 218.A ND2 GLY 271.A O no hydrogen 2.823 N/A LEU 219.A N PRO 239.A O no hydrogen 2.885 N/A PHE 220.A N VAL 171.A O no hydrogen 3.056 N/A VAL 221.A N ALA 242.A O no hydrogen 3.215 N/A GLU 222.A N GLU 222.A OE1 no hydrogen 2.641 N/A THR 223.A N ILE 244.A O no hydrogen 2.876 N/A SER 224.A OG THR 246.A OG1 no hydrogen 3.255 N/A ARG 228.A N ASP 226.A OD1 no hydrogen 2.939 N/A SER 231.A N ARG 228.A O no hydrogen 3.055 N/A VAL 232.A N SER 229.A O no hydrogen 2.845 N/A SER 233.A OG VAL 238.A O no hydrogen 2.735 N/A LYS 234.A N GLU 230.A O no hydrogen 2.993 N/A GLU 235.A N SER 231.A O no hydrogen 2.855 N/A THR 236.A N VAL 232.A O no hydrogen 2.972 N/A THR 236.A OG1 VAL 232.A O no hydrogen 2.671 N/A THR 236.A OG1 SER 233.A O no hydrogen 3.501 N/A GLY 237.A N SER 233.A O no hydrogen 2.687 N/A VAL 238.A N THR 236.A OG1 no hydrogen 3.202 N/A PHE 241.A N LEU 219.A O no hydrogen 2.739 N/A ILE 244.A N VAL 221.A O no hydrogen 2.824 N/A PHE 245.A N ASN 264.A OD1 no hydrogen 2.922 N/A THR 246.A OG1 SER 224.A OG no hydrogen 3.255 N/A THR 246.A OG1 ASP 247.A OD1 no hydrogen 3.509 N/A SER 248.A OG SER 9.A OG no hydrogen 3.286 N/A SER 248.A OG THR 249.A O no hydrogen 2.766 N/A THR 249.A N SER 9.A OG no hydrogen 3.030 N/A THR 249.A OG1 ALA 250.A O no hydrogen 2.901 N/A ALA 250.A N GLY 256.A O no hydrogen 2.864 N/A GLY 253.A N ASP 257.A OD2 no hydrogen 2.874 N/A GLU 254.A N LYS 251.A O no hydrogen 2.956 N/A GLY 256.A N GLU 261.A OE2 no hydrogen 2.748 N/A TYR 259.A N ASP 13.A OD2 no hydrogen 2.807 N/A TYR 259.A OH TRP 110.A O no hydrogen 2.688 N/A GLU 261.A N THR 258.A OG1 no hydrogen 3.048 N/A TYR 263.A N GLU 261.A O no hydrogen 2.924 N/A ASN 264.A ND2 PHE 245.A O no hydrogen 2.880 N/A ASP 266.A N ARG 262.A O no hydrogen 2.926 N/A LYS 267.A N TYR 263.A O no hydrogen 2.905 N/A ILE 268.A N ASN 264.A O no hydrogen 3.013 N/A HIS 269.A N LEU 265.A O no hydrogen 3.049 N/A ASP 270.A N ASP 266.A O no hydrogen 2.863 N/A GLY 271.A N LYS 267.A O no hydrogen 2.916 N/A LEU 272.A N ILE 268.A O no hydrogen 3.003 N/A