Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5i9v_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 4.A N VAL 77.A O no hydrogen 2.799 N/A HIS 5.A ND1 SER 7.A OG no hydrogen 2.763 N/A SER 7.A N HIS 5.A ND1 no hydrogen 3.219 N/A SER 7.A OG HIS 5.A ND1 no hydrogen 2.763 N/A CYS 8.A N HIS 5.A O no hydrogen 2.903 N/A VAL 9.A N PRO 6.A O no hydrogen 3.244 N/A THR 10.A N MET 27.A O no hydrogen 3.068 N/A THR 10.A OG1 MET 27.A O no hydrogen 3.540 N/A GLN 12.A N LYS 25.A O no hydrogen 2.827 N/A LYS 13.A N LYS 25.A O no hydrogen 3.211 N/A ILE 15.A N VAL 23.A O no hydrogen 3.005 N/A VAL 23.A N GLY 16.A O no hydrogen 3.069 N/A TYR 24.A N ILE 41.A O no hydrogen 2.846 N/A LYS 25.A N LYS 13.A O no hydrogen 2.712 N/A LYS 25.A NZ GLN 12.A OE1 no hydrogen 3.308 N/A LYS 25.A NZ GLY 26.A O no hydrogen 3.021 N/A GLY 26.A N VAL 39.A O no hydrogen 2.839 N/A MET 27.A N THR 10.A O no hydrogen 3.078 N/A LEU 28.A N VAL 37.A O no hydrogen 2.851 N/A LYS 29.A N CYS 8.A O no hydrogen 2.862 N/A THR 30.A N LYS 35.A O no hydrogen 2.851 N/A GLY 33.A N THR 30.A O no hydrogen 2.842 N/A LYS 34.A N SER 31.A O no hydrogen 3.274 N/A LYS 35.A N THR 30.A O no hydrogen 3.201 N/A VAL 37.A N LEU 28.A O no hydrogen 2.900 N/A VAL 39.A N GLY 26.A O no hydrogen 2.940 N/A ALA 40.A N THR 88.A O no hydrogen 2.840 N/A ILE 41.A N TYR 24.A O no hydrogen 2.780 N/A LYS 42.A N ILE 86.A O no hydrogen 2.982 N/A LYS 42.A NZ GLU 59.A OE2 no hydrogen 2.822 N/A THR 43.A N GLU 22.A O no hydrogen 3.383 N/A LEU 44.A N MET 84.A O no hydrogen 2.989 N/A LYS 45.A NZ ALA 46.A O no hydrogen 3.426 N/A THR 49.A N GLN 52.A OE1 no hydrogen 2.884 N/A THR 49.A OG1 GLN 52.A OE1 no hydrogen 3.397 N/A LYS 51.A NZ ASP 55.A OD2 no hydrogen 2.778 N/A GLN 52.A N THR 49.A OG1 no hydrogen 3.133 N/A ARG 53.A N THR 49.A O no hydrogen 2.983 N/A VAL 54.A N GLU 50.A O no hydrogen 2.889 N/A ASP 55.A N LYS 51.A O no hydrogen 2.866 N/A PHE 56.A N GLN 52.A O no hydrogen 2.803 N/A LEU 57.A N ARG 53.A O no hydrogen 2.897 N/A GLY 58.A N VAL 54.A O no hydrogen 2.819 N/A GLU 59.A N ASP 55.A O no hydrogen 3.117 N/A GLY 61.A N LEU 57.A O no hydrogen 2.898 N/A ILE 62.A N GLY 58.A O no hydrogen 2.967 N/A MET 63.A N GLU 59.A O no hydrogen 2.969 N/A GLY 64.A N ALA 60.A O no hydrogen 2.880 N/A GLN 65.A N ILE 62.A O no hydrogen 2.993 N/A GLN 65.A NE2 GLY 61.A O no hydrogen 3.314 N/A PHE 66.A N MET 63.A O no hydrogen 3.122 N/A SER 67.A N TYR 125.A OH no hydrogen 2.958 N/A ASN 70.A N HIS 68.A ND1 no hydrogen 2.906 N/A ASN 70.A ND2 CYS 149.A O no hydrogen 2.935 N/A ILE 71.A N HIS 68.A O no hydrogen 3.100 N/A ILE 72.A N VAL 151.A O no hydrogen 3.062 N/A ARG 73.A N GLU 89.A OE2 no hydrogen 2.770 N/A ARG 73.A NE GLU 75.A OE2 no hydrogen 2.778 N/A ARG 73.A NH2 GLU 75.A OE2 no hydrogen 2.835 N/A GLU 75.A N ILE 87.A O no hydrogen 2.777 N/A GLY 76.A N ILE 87.A O no hydrogen 3.266 N/A VAL 77.A N THR 2.A O no hydrogen 2.922 N/A ILE 78.A N MET 85.A O no hydrogen 2.923 N/A SER 79.A N GLU 3.A OE2 no hydrogen 2.839 N/A SER 79.A OG GLU 3.A OE1 no hydrogen 2.886 N/A SER 79.A OG GLU 3.A OE2 no hydrogen 3.533 N/A LYS 80.A N GLU 3.A OE2 no hydrogen 2.932 N/A LYS 82.A NZ SER 79.A O no hydrogen 2.840 N/A MET 85.A N ILE 78.A O no hydrogen 2.902 N/A ILE 86.A N LYS 42.A O no hydrogen 2.869 N/A ILE 87.A N GLY 76.A O no hydrogen 2.928 N/A THR 88.A N ALA 40.A O no hydrogen 2.953 N/A GLU 89.A N ARG 73.A O no hydrogen 3.016 N/A TYR 90.A N PRO 38.A O no hydrogen 3.429 N/A GLU 92.A N.A GLU 92.A OE1.A no hydrogen 2.822 N/A ASN 93.A N VAL 143.A O no hydrogen 2.894 N/A ASN 93.A ND2 ASN 144.A O no hydrogen 3.027 N/A GLY 94.A N MET 91.A O no hydrogen 3.031 N/A LEU 96.A N ILE 141.A O.A no hydrogen 2.882 N/A LEU 96.A N ILE 141.A O.B no hydrogen 2.729 N/A LYS 98.A N ASP 97.A OD1 no hydrogen 2.724 N/A LYS 98.A NZ GLU 102.A OE2 no hydrogen 2.551 N/A PHE 99.A N ALA 95.A O no hydrogen 2.924 N/A LEU 100.A N LEU 96.A O no hydrogen 2.895 N/A ARG 101.A N ASP 97.A O no hydrogen 3.081 N/A ARG 101.A NE GLY 197.A O no hydrogen 2.775 N/A ARG 101.A NH1 GLY 197.A O no hydrogen 3.497 N/A GLU 102.A N LYS 98.A O no hydrogen 3.151 N/A GLU 102.A N PHE 99.A O no hydrogen 3.070 N/A LYS 103.A N LEU 100.A O no hydrogen 3.000 N/A GLU 106.A N LYS 103.A O no hydrogen 2.969 N/A PHE 107.A N TYR 196.A OH no hydrogen 2.958 N/A SER 108.A N GLN 111.A OE1 no hydrogen 2.996 N/A GLN 111.A N SER 108.A OG no hydrogen 3.007 N/A LEU 112.A N SER 108.A O no hydrogen 3.030 N/A VAL 113.A N VAL 109.A O no hydrogen 2.903 N/A GLY 114.A N LEU 110.A O no hydrogen 2.906 N/A MET 115.A N GLN 111.A O no hydrogen 3.008 N/A LEU 116.A N LEU 112.A O no hydrogen 3.076 N/A ARG 117.A N VAL 113.A O no hydrogen 2.876 N/A ARG 117.A NE ASP 255.A OD1 no hydrogen 2.510 N/A ARG 117.A NE ASP 255.A OD2 no hydrogen 3.447 N/A ARG 117.A NH2 ASP 255.A OD2 no hydrogen 2.859 N/A GLY 118.A N GLY 114.A O no hydrogen 3.061 N/A ILE 119.A N MET 115.A O no hydrogen 2.984 N/A ALA 120.A N LEU 116.A O no hydrogen 2.836 N/A ALA 121.A N ARG 117.A O no hydrogen 2.844 N/A GLY 122.A N GLY 118.A O no hydrogen 3.013 N/A MET 123.A N ILE 119.A O no hydrogen 2.908 N/A LYS 124.A N ALA 120.A O no hydrogen 2.735 N/A TYR 125.A N ALA 121.A O no hydrogen 3.043 N/A LEU 126.A N GLY 122.A O no hydrogen 2.933 N/A ALA 127.A N MET 123.A O no hydrogen 2.871 N/A ASN 128.A N LYS 124.A O no hydrogen 2.947 N/A MET 129.A N TYR 125.A O no hydrogen 2.936 N/A ASN 130.A N.A ALA 127.A O no hydrogen 2.925 N/A ASN 130.A N.B ALA 127.A O no hydrogen 2.924 N/A TYR 131.A N LEU 126.A O no hydrogen 3.152 N/A TYR 131.A OH GLN 65.A OE1 no hydrogen 2.862 N/A VAL 132.A N ARG 158.A O no hydrogen 2.918 N/A HIS 133.A N ASP 182.A OD2 no hydrogen 2.740 N/A HIS 133.A NE2 SER 152.A O.A no hydrogen 2.940 N/A HIS 133.A NE2 SER 152.A O.B no hydrogen 3.012 N/A ARG 134.A N ASP 182.A OD1 no hydrogen 3.080 N/A ARG 134.A NE LEU 156.A O no hydrogen 2.655 N/A ARG 134.A NH2 LEU 156.A O no hydrogen 2.918 N/A ASP 135.A N HIS 133.A ND1 no hydrogen 3.100 N/A ALA 138.A N GLU 192.A OE2 no hydrogen 2.858 N/A ASN 140.A N ALA 137.A O no hydrogen 2.845 N/A ASN 140.A ND2 ASP 135.A O no hydrogen 2.718 N/A ASN 140.A ND2 ASP 135.A OD2 no hydrogen 2.947 N/A ILE 141.A N.A ALA 138.A O no hydrogen 3.149 N/A ILE 141.A N.B ALA 138.A O no hydrogen 3.164 N/A LEU 142.A N LYS 150.A O no hydrogen 2.928 N/A VAL 143.A N GLY 94.A O no hydrogen 2.920 N/A ASN 144.A N VAL 148.A O no hydrogen 3.072 N/A SER 145.A N GLU 92.A OE1.A no hydrogen 3.073 N/A SER 145.A OG GLU 92.A OE2.A no hydrogen 3.201 N/A ASN 146.A N ASN 144.A OD1 no hydrogen 2.915 N/A LEU 147.A N ASN 144.A O no hydrogen 3.072 N/A VAL 148.A N ASN 144.A OD1 no hydrogen 3.044 N/A CYS 149.A SG LEU 147.A O no hydrogen 4.020 N/A LYS 150.A N LEU 142.A O no hydrogen 2.857 N/A LYS 150.A NZ HIS 69.A O no hydrogen 3.122 N/A LYS 150.A NZ GLU 89.A OE1 no hydrogen 3.114 N/A LYS 150.A NZ GLU 89.A OE2 no hydrogen 3.446 N/A VAL 151.A N ASN 70.A O no hydrogen 2.833 N/A SER 152.A N.A ASN 140.A O no hydrogen 2.936 N/A SER 152.A N.B ASN 140.A O no hydrogen 2.923 N/A SER 152.A OG.A ASN 140.A O no hydrogen 2.871 N/A ASP 153.A N SER 152.A OG.B no hydrogen 2.703 N/A GLY 155.A N ASP 153.A OD1 no hydrogen 3.387 N/A SER 157.A N PHE 154.A O no hydrogen 3.091 N/A ARG 158.A N VAL 132.A O no hydrogen 3.055 N/A LEU 160.A N ASN 130.A O.A no hydrogen 2.993 N/A LEU 160.A N ASN 130.A O.B no hydrogen 2.951 N/A ARG 165.A NH1 LEU 204.A O no hydrogen 2.910 N/A ARG 165.A NH1 ASN 206.A OD1 no hydrogen 3.103 N/A ARG 165.A NH2 PRO 200.A O no hydrogen 3.035 N/A ARG 165.A NH2 LEU 204.A O no hydrogen 3.027 N/A TRP 166.A N PRO 163.A O no hydrogen 3.242 N/A TRP 166.A NE1 GLU 192.A OE2 no hydrogen 2.796 N/A THR 167.A N ILE 164.A O no hydrogen 2.968 N/A THR 167.A OG1 PRO 163.A O no hydrogen 2.838 N/A GLU 170.A N GLU 170.A OE1 no hydrogen 2.820 N/A ALA 171.A N ALA 168.A O no hydrogen 3.066 N/A ILE 172.A N ALA 168.A O no hydrogen 3.035 N/A SER 173.A N PRO 169.A O no hydrogen 3.018 N/A SER 173.A OG PRO 169.A O no hydrogen 3.417 N/A TYR 174.A N GLU 170.A O no hydrogen 3.051 N/A ARG 175.A N ALA 171.A O no hydrogen 3.092 N/A ARG 175.A NH1 ILE 172.A O no hydrogen 3.386 N/A LYS 176.A N GLU 170.A O no hydrogen 3.354 N/A THR 178.A N SER 181.A OG no hydrogen 2.881 N/A ALA 180.A N THR 178.A OG1 no hydrogen 3.013 N/A SER 181.A N THR 178.A OG1 no hydrogen 3.392 N/A SER 181.A OG THR 178.A O no hydrogen 2.912 N/A ASP 182.A N THR 178.A O no hydrogen 3.025 N/A VAL 183.A N SER 179.A O no hydrogen 2.890 N/A TRP 184.A N ALA 180.A O no hydrogen 3.255 N/A SER 185.A N SER 181.A O no hydrogen 3.142 N/A SER 185.A OG TRP 166.A O no hydrogen 2.677 N/A SER 185.A OG SER 181.A O no hydrogen 3.279 N/A PHE 186.A N ASP 182.A O no hydrogen 2.821 N/A GLY 187.A N VAL 183.A O no hydrogen 2.980 N/A ILE 188.A N TRP 184.A O no hydrogen 3.194 N/A VAL 189.A N SER 185.A O no hydrogen 2.875 N/A MET 190.A N PHE 186.A O no hydrogen 2.768 N/A TRP 191.A N GLY 187.A O no hydrogen 3.117 N/A TRP 191.A NE1 PRO 220.A O no hydrogen 2.823 N/A GLU 192.A N ILE 188.A O no hydrogen 2.807 N/A VAL 193.A N VAL 189.A O no hydrogen 2.841 N/A MET 194.A N MET 190.A O no hydrogen 2.961 N/A THR 195.A N TRP 191.A O no hydrogen 3.074 N/A THR 195.A OG1 TRP 191.A O no hydrogen 2.882 N/A THR 195.A OG1 GLU 192.A O no hydrogen 3.167 N/A TYR 196.A N VAL 193.A O no hydrogen 3.102 N/A GLY 197.A N GLU 192.A O no hydrogen 2.744 N/A GLU 198.A N THR 195.A OG1 no hydrogen 3.086 N/A ARG 199.A NE TRP 202.A O no hydrogen 3.371 N/A TRP 202.A N ARG 199.A O no hydrogen 2.958 N/A TRP 202.A NE1 GLU 198.A OE1 no hydrogen 2.755 N/A GLU 203.A N GLU 203.A OE1 no hydrogen 2.742 N/A LEU 204.A N TYR 201.A O no hydrogen 3.131 N/A SER 205.A N GLU 208.A OE1 no hydrogen 2.907 N/A GLU 208.A N SER 205.A OG no hydrogen 3.185 N/A VAL 209.A N SER 205.A O no hydrogen 2.768 N/A MET 210.A N.A ASN 206.A O no hydrogen 2.971 N/A MET 210.A N.B ASN 206.A O no hydrogen 2.960 N/A LYS 211.A N HIS 207.A O no hydrogen 2.904 N/A ALA 212.A N GLU 208.A O no hydrogen 3.014 N/A ILE 213.A N VAL 209.A O no hydrogen 2.954 N/A ASN 214.A N MET 210.A O.A no hydrogen 3.016 N/A ASN 214.A N MET 210.A O.B no hydrogen 3.001 N/A ASP 215.A N LYS 211.A O no hydrogen 3.192 N/A ASP 215.A N ALA 212.A O no hydrogen 3.144 N/A GLY 216.A N ILE 213.A O no hydrogen 2.970 N/A PHE 217.A N ALA 212.A O no hydrogen 2.981 N/A ARG 218.A NE TRP 237.A O no hydrogen 2.971 N/A ARG 218.A NH1 ILE 213.A O no hydrogen 2.904 N/A ARG 218.A NH1 PHE 217.A O no hydrogen 2.930 N/A ARG 218.A NH2 TRP 237.A O no hydrogen 2.949 N/A THR 221.A OG1.A PRO 222.A O no hydrogen 3.014 N/A CYS 225.A SG PRO 226.A O no hydrogen 3.626 N/A SER 227.A N THR 266.A O no hydrogen 2.738 N/A TYR 230.A N PRO 226.A O no hydrogen 3.057 N/A TYR 230.A OH LEU 219.A O no hydrogen 2.586 N/A GLN 231.A N SER 227.A O no hydrogen 2.868 N/A GLN 231.A NE2 SER 227.A O no hydrogen 3.474 N/A GLN 231.A NE2 SER 227.A OG no hydrogen 2.866 N/A LEU 232.A N ALA 228.A O no hydrogen 2.976 N/A MET 233.A N ILE 229.A O no hydrogen 2.994 N/A MET 234.A N TYR 230.A O no hydrogen 2.953 N/A GLN 235.A N.A GLN 231.A O no hydrogen 3.053 N/A GLN 235.A N.B GLN 231.A O no hydrogen 3.071 N/A GLN 235.A N.B LEU 232.A O no hydrogen 3.124 N/A CYS 236.A N LEU 232.A O no hydrogen 3.097 N/A CYS 236.A SG LEU 232.A O no hydrogen 3.465 N/A TRP 237.A N MET 234.A O no hydrogen 3.023 N/A GLN 238.A N GLN 235.A O.A no hydrogen 3.244 N/A GLN 238.A N GLN 235.A O.B no hydrogen 3.368 N/A GLN 238.A NE2 GLN 235.A OE1.A no hydrogen 3.057 N/A ARG 243.A N GLU 240.A O no hydrogen 2.990 N/A ARG 244.A N ARG 241.A O no hydrogen 3.172 N/A ARG 244.A NE GLN 238.A O no hydrogen 2.771 N/A ARG 244.A NH1 GLU 170.A OE2 no hydrogen 2.892 N/A ARG 244.A NH1 ALA 180.A O no hydrogen 2.922 N/A ARG 244.A NH2 GLU 170.A OE1 no hydrogen 2.861 N/A ARG 244.A NH2 GLN 238.A O no hydrogen 3.112 N/A ARG 244.A NH2 GLN 239.A O no hydrogen 3.181 N/A LYS 246.A N ASP 249.A OD2 no hydrogen 2.856 N/A ILE 250.A N LYS 246.A O no hydrogen 3.077 N/A VAL 251.A N PHE 247.A O no hydrogen 2.930 N/A SER 252.A N ALA 248.A O no hydrogen 3.007 N/A ILE 253.A N ASP 249.A O no hydrogen 2.888 N/A LEU 254.A N ILE 250.A O no hydrogen 3.013 N/A ASP 255.A N VAL 251.A O no hydrogen 2.928 N/A LYS 256.A N SER 252.A O no hydrogen 2.974 N/A LYS 256.A NZ SER 252.A OG no hydrogen 3.283 N/A LEU 257.A N ILE 253.A O no hydrogen 2.978 N/A ILE 258.A N LEU 254.A O no hydrogen 2.960 N/A ARG 259.A N ASP 255.A O no hydrogen 3.028 N/A ALA 260.A N LYS 256.A O no hydrogen 3.137 N/A ALA 260.A N LEU 257.A O no hydrogen 3.302 N/A SER 263.A N ALA 260.A O no hydrogen 2.823 N/A SER 263.A OG LEU 257.A O no hydrogen 3.277 N/A SER 263.A OG ALA 260.A O no hydrogen 2.614 N/A LEU 264.A N PRO 261.A O no hydrogen 3.007 N/A LYS 265.A N ASP 262.A O no hydrogen 3.097 N/A LYS 265.A NZ ASP 262.A OD1 no hydrogen 2.923 N/A ALA 268.A N CYS 225.A O no hydrogen 2.884 N/A