Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5i9z_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ILE 5.A N VAL 72.A O no hydrogen 2.840 N/A HIS 6.A ND1 SER 8.A OG no hydrogen 2.761 N/A SER 8.A N HIS 6.A ND1 no hydrogen 3.072 N/A SER 8.A OG HIS 6.A ND1 no hydrogen 2.761 N/A CYS 9.A N HIS 6.A O no hydrogen 2.873 N/A VAL 10.A N PRO 7.A O no hydrogen 3.220 N/A THR 11.A N MET 26.A O no hydrogen 2.981 N/A GLN 13.A N LYS 24.A O no hydrogen 2.906 N/A LYS 14.A N LYS 24.A O no hydrogen 3.223 N/A ILE 16.A N VAL 22.A O no hydrogen 2.759 N/A GLU 21.A N THR 38.A OG1 no hydrogen 3.375 N/A VAL 22.A N GLY 17.A O no hydrogen 2.970 N/A TYR 23.A N ILE 36.A O no hydrogen 2.737 N/A TYR 23.A OH GLU 21.A OE2 no hydrogen 2.490 N/A LYS 24.A N LYS 14.A O no hydrogen 2.880 N/A LYS 24.A NZ GLN 13.A OE1 no hydrogen 3.093 N/A GLY 25.A N VAL 34.A O no hydrogen 2.913 N/A MET 26.A N THR 11.A O no hydrogen 2.926 N/A LEU 27.A N VAL 32.A O no hydrogen 2.855 N/A LYS 28.A N CYS 9.A O no hydrogen 2.856 N/A VAL 32.A N LEU 27.A O no hydrogen 3.014 N/A VAL 34.A N GLY 25.A O no hydrogen 2.965 N/A ALA 35.A N THR 83.A O no hydrogen 2.867 N/A ILE 36.A N TYR 23.A O no hydrogen 2.832 N/A LYS 37.A N ILE 81.A O no hydrogen 2.886 N/A LYS 37.A NZ GLU 54.A OE1 no hydrogen 3.508 N/A LYS 37.A NZ GLU 54.A OE2 no hydrogen 3.003 N/A THR 38.A N GLU 21.A O no hydrogen 3.283 N/A THR 38.A OG1 GLU 21.A O no hydrogen 3.408 N/A THR 38.A OG1 GLU 21.A OE2 no hydrogen 3.252 N/A LEU 39.A N MET 79.A O no hydrogen 2.990 N/A TYR 43.A N LYS 40.A O no hydrogen 3.294 N/A THR 44.A N GLN 47.A OE1 no hydrogen 2.934 N/A THR 44.A OG1 GLN 47.A OE1 no hydrogen 3.500 N/A GLN 47.A N THR 44.A OG1 no hydrogen 3.100 N/A ARG 48.A N THR 44.A O no hydrogen 3.033 N/A VAL 49.A N GLU 45.A O no hydrogen 2.950 N/A ASP 50.A N LYS 46.A O no hydrogen 2.881 N/A PHE 51.A N GLN 47.A O no hydrogen 2.765 N/A LEU 52.A N ARG 48.A O no hydrogen 2.880 N/A GLY 53.A N VAL 49.A O no hydrogen 2.720 N/A GLU 54.A N ASP 50.A O no hydrogen 2.949 N/A ALA 55.A N PHE 51.A O no hydrogen 3.329 N/A GLY 56.A N LEU 52.A O no hydrogen 2.732 N/A ILE 57.A N GLY 53.A O no hydrogen 2.802 N/A MET 58.A N GLU 54.A O no hydrogen 3.015 N/A GLY 59.A N ALA 55.A O no hydrogen 2.835 N/A GLN 60.A N ILE 57.A O no hydrogen 3.055 N/A PHE 61.A N MET 58.A O no hydrogen 3.194 N/A SER 62.A N.A TYR 120.A OH no hydrogen 3.002 N/A SER 62.A N.B TYR 120.A OH no hydrogen 2.997 N/A ASN 65.A N HIS 63.A ND1 no hydrogen 2.961 N/A ASN 65.A ND2 CYS 144.A O no hydrogen 2.972 N/A ILE 66.A N HIS 63.A O no hydrogen 3.103 N/A ILE 67.A N VAL 146.A O no hydrogen 3.258 N/A ARG 68.A N GLU 84.A OE1 no hydrogen 2.712 N/A ARG 68.A NE GLU 70.A OE2 no hydrogen 3.356 N/A ARG 68.A NH2 GLU 70.A OE2 no hydrogen 3.298 N/A GLU 70.A N ILE 82.A O no hydrogen 2.731 N/A GLY 71.A N ILE 82.A O no hydrogen 3.241 N/A VAL 72.A N THR 3.A O no hydrogen 2.822 N/A ILE 73.A N MET 80.A O no hydrogen 2.823 N/A SER 74.A N GLU 4.A OE2 no hydrogen 2.789 N/A SER 74.A OG GLU 4.A OE1 no hydrogen 2.659 N/A SER 74.A OG GLU 4.A OE2 no hydrogen 3.462 N/A LYS 75.A N GLU 4.A OE2 no hydrogen 3.051 N/A LYS 77.A NZ TYR 43.A OH no hydrogen 3.313 N/A MET 80.A N ILE 73.A O no hydrogen 2.964 N/A ILE 81.A N LYS 37.A O no hydrogen 2.860 N/A ILE 82.A N GLY 71.A O no hydrogen 2.917 N/A THR 83.A N ALA 35.A O no hydrogen 2.920 N/A THR 83.A OG1 GLU 84.A O no hydrogen 3.510 N/A GLU 84.A N ARG 68.A O no hydrogen 3.055 N/A GLU 87.A N GLU 87.A OE1 no hydrogen 2.830 N/A ASN 88.A N VAL 138.A O no hydrogen 2.874 N/A GLY 89.A N MET 86.A O no hydrogen 3.359 N/A LEU 91.A N ILE 136.A O.A no hydrogen 2.986 N/A LEU 91.A N ILE 136.A O.B no hydrogen 2.715 N/A PHE 94.A N ALA 90.A O no hydrogen 2.968 N/A LEU 95.A N LEU 91.A O no hydrogen 2.904 N/A ARG 96.A N ASP 92.A O no hydrogen 3.161 N/A ARG 96.A NE GLY 191.A O no hydrogen 2.704 N/A ARG 96.A NH1 GLY 191.A O no hydrogen 3.457 N/A GLU 97.A N LYS 93.A O no hydrogen 2.984 N/A LYS 98.A N LEU 95.A O no hydrogen 3.118 N/A GLU 101.A N LYS 98.A O no hydrogen 3.034 N/A PHE 102.A N TYR 190.A OH no hydrogen 2.984 N/A SER 103.A N GLN 106.A OE1 no hydrogen 2.811 N/A GLN 106.A N SER 103.A OG no hydrogen 3.003 N/A LEU 107.A N SER 103.A O no hydrogen 3.000 N/A VAL 108.A N VAL 104.A O no hydrogen 2.906 N/A GLY 109.A N LEU 105.A O no hydrogen 2.945 N/A MET 110.A N GLN 106.A O no hydrogen 3.011 N/A LEU 111.A N LEU 107.A O no hydrogen 3.199 N/A ARG 112.A N.A VAL 108.A O no hydrogen 2.841 N/A ARG 112.A N.B VAL 108.A O no hydrogen 2.845 N/A ARG 112.A NE.B ASP 249.A OD1.A no hydrogen 2.253 N/A ARG 112.A NH1.A ASP 249.A OD1.B no hydrogen 2.952 N/A ARG 112.A NH2.B ASP 249.A OD2.A no hydrogen 2.895 N/A GLY 113.A N GLY 109.A O no hydrogen 3.050 N/A ILE 114.A N MET 110.A O no hydrogen 3.068 N/A ALA 115.A N LEU 111.A O no hydrogen 2.883 N/A ALA 116.A N ARG 112.A O.A no hydrogen 2.860 N/A ALA 116.A N ARG 112.A O.B no hydrogen 2.864 N/A GLY 117.A N GLY 113.A O no hydrogen 3.016 N/A MET 118.A N ILE 114.A O no hydrogen 2.874 N/A LYS 119.A N ALA 115.A O no hydrogen 2.737 N/A TYR 120.A N ALA 116.A O no hydrogen 3.022 N/A LEU 121.A N GLY 117.A O no hydrogen 2.925 N/A ALA 122.A N MET 118.A O no hydrogen 2.899 N/A ASN 123.A N LYS 119.A O no hydrogen 3.042 N/A MET 124.A N TYR 120.A O no hydrogen 2.919 N/A ASN 125.A N ALA 122.A O no hydrogen 2.888 N/A TYR 126.A N LEU 121.A O no hydrogen 2.856 N/A TYR 126.A OH GLY 150.A O no hydrogen 3.057 N/A HIS 128.A N ASP 176.A OD2 no hydrogen 2.792 N/A HIS 128.A NE2 SER 147.A O no hydrogen 2.770 N/A ARG 129.A N.A ASP 176.A OD1 no hydrogen 3.055 N/A ARG 129.A N.B ASP 176.A OD1 no hydrogen 3.054 N/A ARG 129.A NE.A VAL 127.A O no hydrogen 2.948 N/A ARG 129.A NH1.A LEU 151.A O no hydrogen 2.724 N/A ARG 129.A NH2.A VAL 127.A O no hydrogen 3.236 N/A ARG 129.A NH2.A GLY 150.A O no hydrogen 2.911 N/A ASP 130.A N HIS 128.A ND1 no hydrogen 3.107 N/A ALA 133.A N GLU 186.A OE2 no hydrogen 2.944 N/A ARG 134.A NH2 ASP 130.A OD1 no hydrogen 3.320 N/A ASN 135.A N ALA 132.A O no hydrogen 2.905 N/A ASN 135.A ND2 ASP 130.A O no hydrogen 2.709 N/A ASN 135.A ND2 ASP 130.A OD2 no hydrogen 3.065 N/A ILE 136.A N.A ALA 133.A O no hydrogen 3.101 N/A ILE 136.A N.B ALA 133.A O no hydrogen 3.109 N/A LEU 137.A N LYS 145.A O no hydrogen 2.939 N/A VAL 138.A N GLY 89.A O no hydrogen 2.914 N/A ASN 139.A N VAL 143.A O no hydrogen 3.119 N/A SER 140.A N GLU 87.A OE1 no hydrogen 2.857 N/A SER 140.A OG GLU 87.A OE1 no hydrogen 3.540 N/A SER 140.A OG GLU 87.A OE2 no hydrogen 3.562 N/A ASN 141.A N ASN 139.A OD1 no hydrogen 2.862 N/A LEU 142.A N ASN 139.A O no hydrogen 3.026 N/A VAL 143.A N ASN 139.A OD1 no hydrogen 2.983 N/A CYS 144.A SG LEU 142.A O no hydrogen 4.018 N/A LYS 145.A N LEU 137.A O no hydrogen 2.893 N/A LYS 145.A NZ HIS 64.A O no hydrogen 3.203 N/A LYS 145.A NZ GLU 84.A OE1 no hydrogen 3.381 N/A LYS 145.A NZ GLU 84.A OE2 no hydrogen 2.806 N/A VAL 146.A N ASN 65.A O no hydrogen 2.918 N/A SER 147.A N ASN 135.A O no hydrogen 3.063 N/A ASP 148.A N SER 147.A OG no hydrogen 2.643 N/A GLY 150.A N TYR 126.A OH no hydrogen 3.117 N/A ARG 159.A NH1 LEU 198.A O no hydrogen 2.736 N/A ARG 159.A NH1 ASN 200.A OD1 no hydrogen 3.139 N/A ARG 159.A NH2 PRO 194.A O no hydrogen 3.033 N/A ARG 159.A NH2 LEU 198.A O no hydrogen 3.108 N/A TRP 160.A N PRO 157.A O no hydrogen 3.099 N/A TRP 160.A NE1 GLU 186.A OE2 no hydrogen 2.804 N/A THR 161.A N ILE 158.A O no hydrogen 3.068 N/A THR 161.A OG1 PRO 157.A O no hydrogen 2.703 N/A GLU 164.A N GLU 164.A OE1 no hydrogen 2.793 N/A ALA 165.A N ALA 162.A O no hydrogen 3.047 N/A ILE 166.A N ALA 162.A O no hydrogen 3.075 N/A SER 167.A N PRO 163.A O no hydrogen 2.797 N/A SER 167.A OG PRO 163.A O no hydrogen 3.156 N/A TYR 168.A N GLU 164.A O no hydrogen 3.010 N/A ARG 169.A N ALA 165.A O no hydrogen 3.013 N/A LYS 170.A N GLU 164.A O no hydrogen 3.288 N/A THR 172.A N SER 175.A OG no hydrogen 2.829 N/A ALA 174.A N THR 172.A OG1 no hydrogen 3.015 N/A SER 175.A N THR 172.A OG1 no hydrogen 3.308 N/A SER 175.A OG THR 172.A O no hydrogen 2.846 N/A ASP 176.A N THR 172.A O no hydrogen 3.014 N/A VAL 177.A N SER 173.A O no hydrogen 2.967 N/A TRP 178.A N ALA 174.A O no hydrogen 3.234 N/A SER 179.A N SER 175.A O no hydrogen 3.101 N/A SER 179.A OG TRP 160.A O no hydrogen 2.702 N/A SER 179.A OG SER 175.A O no hydrogen 3.311 N/A PHE 180.A N ASP 176.A O no hydrogen 2.760 N/A GLY 181.A N VAL 177.A O no hydrogen 2.945 N/A ILE 182.A N TRP 178.A O no hydrogen 3.146 N/A VAL 183.A N SER 179.A O no hydrogen 2.853 N/A MET 184.A N PHE 180.A O no hydrogen 2.780 N/A TRP 185.A N GLY 181.A O no hydrogen 3.144 N/A TRP 185.A NE1 PRO 214.A O no hydrogen 2.922 N/A GLU 186.A N ILE 182.A O no hydrogen 2.822 N/A VAL 187.A N VAL 183.A O no hydrogen 2.874 N/A MET 188.A N MET 184.A O no hydrogen 3.032 N/A THR 189.A N TRP 185.A O no hydrogen 3.082 N/A THR 189.A OG1 TRP 185.A O no hydrogen 2.806 N/A THR 189.A OG1 GLU 186.A O no hydrogen 3.184 N/A TYR 190.A N VAL 187.A O no hydrogen 3.100 N/A GLY 191.A N GLU 186.A O no hydrogen 2.761 N/A GLU 192.A N.A THR 189.A OG1 no hydrogen 3.112 N/A GLU 192.A N.B THR 189.A OG1 no hydrogen 3.123 N/A TRP 196.A N ARG 193.A O no hydrogen 2.954 N/A TRP 196.A NE1 GLU 192.A OE1.B no hydrogen 2.647 N/A TRP 196.A NE1 GLU 192.A OE2.A no hydrogen 2.971 N/A GLU 197.A N GLU 197.A OE1 no hydrogen 2.942 N/A LEU 198.A N TYR 195.A O no hydrogen 3.008 N/A SER 199.A N GLU 202.A OE1 no hydrogen 2.770 N/A GLU 202.A N SER 199.A OG no hydrogen 3.026 N/A VAL 203.A N SER 199.A O no hydrogen 2.806 N/A MET 204.A N ASN 200.A O no hydrogen 3.106 N/A LYS 205.A N HIS 201.A O no hydrogen 2.971 N/A LYS 205.A NZ ASP 209.A OD1 no hydrogen 3.092 N/A ALA 206.A N GLU 202.A O no hydrogen 2.850 N/A ILE 207.A N VAL 203.A O no hydrogen 2.879 N/A ASN 208.A N MET 204.A O no hydrogen 2.879 N/A ASP 209.A N LYS 205.A O no hydrogen 2.862 N/A GLY 210.A N ILE 207.A O no hydrogen 2.896 N/A PHE 211.A N.A ALA 206.A O no hydrogen 2.872 N/A PHE 211.A N.B ALA 206.A O no hydrogen 2.882 N/A ARG 212.A NE TRP 231.A O no hydrogen 2.850 N/A ARG 212.A NH1 ILE 207.A O no hydrogen 3.097 N/A ARG 212.A NH1 PHE 211.A O.A no hydrogen 2.833 N/A ARG 212.A NH1 PHE 211.A O.B no hydrogen 2.845 N/A ARG 212.A NH2 TRP 231.A O no hydrogen 2.906 N/A THR 215.A OG1 PRO 216.A O no hydrogen 3.453 N/A THR 215.A OG1 ASP 263.A O no hydrogen 3.007 N/A CYS 219.A SG PRO 220.A O no hydrogen 3.589 N/A SER 221.A N THR 260.A O no hydrogen 2.765 N/A TYR 224.A N PRO 220.A O no hydrogen 3.040 N/A TYR 224.A OH LEU 213.A O no hydrogen 2.654 N/A GLN 225.A N SER 221.A O no hydrogen 2.884 N/A GLN 225.A NE2 SER 221.A O no hydrogen 3.431 N/A GLN 225.A NE2 SER 221.A OG no hydrogen 2.647 N/A LEU 226.A N ALA 222.A O no hydrogen 3.023 N/A MET 227.A N ILE 223.A O no hydrogen 3.043 N/A MET 228.A N TYR 224.A O no hydrogen 2.974 N/A GLN 229.A N GLN 225.A O no hydrogen 3.089 N/A CYS 230.A N LEU 226.A O no hydrogen 3.146 N/A CYS 230.A SG LEU 226.A O no hydrogen 3.466 N/A TRP 231.A N MET 228.A O no hydrogen 3.045 N/A ARG 237.A N GLU 234.A O no hydrogen 2.989 N/A ARG 237.A NE GLN 232.A OE1 no hydrogen 2.986 N/A ARG 238.A N ARG 235.A O no hydrogen 3.159 N/A ARG 238.A NE GLN 232.A O no hydrogen 2.821 N/A ARG 238.A NH1 GLU 164.A OE2 no hydrogen 2.873 N/A ARG 238.A NH1 ALA 174.A O no hydrogen 2.980 N/A ARG 238.A NH2 GLU 164.A OE1 no hydrogen 2.838 N/A ARG 238.A NH2 GLN 232.A O no hydrogen 3.163 N/A ARG 238.A NH2 GLN 233.A O no hydrogen 3.324 N/A LYS 240.A N ASP 243.A OD2 no hydrogen 2.914 N/A ILE 244.A N LYS 240.A O no hydrogen 3.143 N/A VAL 245.A N PHE 241.A O no hydrogen 2.888 N/A SER 246.A N ALA 242.A O no hydrogen 3.080 N/A ILE 247.A N ASP 243.A O no hydrogen 2.974 N/A LEU 248.A N ILE 244.A O no hydrogen 2.954 N/A ASP 249.A N.A VAL 245.A O no hydrogen 2.875 N/A ASP 249.A N.B VAL 245.A O no hydrogen 2.903 N/A LYS 250.A N SER 246.A O no hydrogen 2.999 N/A LEU 251.A N ILE 247.A O no hydrogen 2.900 N/A ILE 252.A N LEU 248.A O no hydrogen 2.966 N/A ARG 253.A N ASP 249.A O.A no hydrogen 2.925 N/A ARG 253.A N ASP 249.A O.B no hydrogen 2.992 N/A ARG 253.A NH2 ASP 249.A OD2.B no hydrogen 2.763 N/A ALA 254.A N LYS 250.A O no hydrogen 3.101 N/A SER 257.A N ALA 254.A O no hydrogen 2.835 N/A SER 257.A OG LEU 251.A O no hydrogen 3.288 N/A SER 257.A OG ALA 254.A O no hydrogen 2.739 N/A LEU 258.A N PRO 255.A O no hydrogen 3.102 N/A LYS 259.A N ASP 256.A O no hydrogen 3.136 N/A LYS 259.A NZ ASP 256.A OD1 no hydrogen 2.986 N/A ALA 262.A N CYS 219.A O no hydrogen 2.895 N/A