Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5ih6_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): VAL 4.A N TYR 8.A O no hydrogen 2.655 N/A TYR 8.A N VAL 4.A O no hydrogen 3.393 N/A ARG 9.A N THR 26.A O no hydrogen 3.090 N/A LEU 10.A N LEU 2.A O no hydrogen 2.899 N/A LYS 13.A NZ ASP 21.A OD2 no hydrogen 3.120 N/A ILE 14.A N ILE 22.A O no hydrogen 2.805 N/A GLY 15.A N ILE 22.A O no hydrogen 3.133 N/A GLY 17.A N GLY 20.A O no hydrogen 2.885 N/A SER 18.A N ASP 148.A OD2 no hydrogen 2.921 N/A SER 18.A OG ASP 148.A OD1 no hydrogen 2.727 N/A SER 18.A OG ASP 148.A OD2 no hydrogen 3.405 N/A ILE 22.A N GLY 15.A O no hydrogen 2.961 N/A TYR 23.A N ILE 36.A O no hydrogen 2.814 N/A LEU 24.A N ARG 12.A O no hydrogen 2.861 N/A GLY 25.A N VAL 34.A O no hydrogen 2.854 N/A THR 26.A N ARG 9.A O no hydrogen 3.032 N/A ASP 27.A N GLU 32.A O no hydrogen 2.862 N/A ILE 28.A N ARG 7.A O no hydrogen 3.203 N/A GLY 31.A N ASP 27.A O no hydrogen 2.941 N/A VAL 34.A N GLY 25.A O no hydrogen 2.931 N/A ALA 35.A N MET 81.A O no hydrogen 3.045 N/A ILE 36.A N TYR 23.A O no hydrogen 2.799 N/A LYS 37.A N MET 79.A O no hydrogen 2.772 N/A LYS 37.A NZ PHE 19.A O no hydrogen 2.999 N/A LYS 37.A NZ GLU 51.A OE1 no hydrogen 3.419 N/A GLU 39.A N ASN 77.A O no hydrogen 2.884 N/A CYS 40.A SG ASP 75.A O no hydrogen 3.884 N/A VAL 41.A N ASP 75.A O no hydrogen 2.854 N/A THR 43.A N CYS 40.A O no hydrogen 2.915 N/A THR 43.A OG1 CYS 40.A O no hydrogen 2.532 N/A GLN 47.A N GLU 39.A OE2 no hydrogen 2.836 N/A GLN 47.A NE2 GLU 39.A OE2 no hydrogen 3.527 N/A LEU 48.A N GLU 39.A OE2 no hydrogen 3.196 N/A GLU 51.A N GLN 47.A O no hydrogen 2.762 N/A SER 52.A N LEU 48.A O no hydrogen 3.026 N/A SER 52.A OG LEU 48.A O no hydrogen 3.127 N/A LYS 53.A N HIS 49.A O no hydrogen 3.087 N/A ILE 54.A N ILE 50.A O no hydrogen 3.462 N/A TYR 55.A N GLU 51.A O no hydrogen 3.242 N/A LYS 56.A N SER 52.A O no hydrogen 2.976 N/A MET 57.A N LYS 53.A O no hydrogen 2.821 N/A MET 58.A N ILE 54.A O no hydrogen 2.925 N/A GLN 59.A N LYS 56.A O no hydrogen 3.286 N/A GLY 61.A N MET 58.A O no hydrogen 3.105 N/A ILE 64.A N GLY 61.A O no hydrogen 3.429 N/A THR 66.A N GLU 82.A OE2 no hydrogen 2.918 N/A THR 66.A OG1 GLU 82.A OE2 no hydrogen 3.342 N/A ARG 68.A N VAL 80.A O no hydrogen 2.769 N/A ARG 68.A NH2 GLU 32.A OE2 no hydrogen 3.335 N/A TRP 69.A N VAL 80.A O no hydrogen 3.323 N/A CYS 70.A SG HIS 49.A ND1 no hydrogen 3.715 N/A CYS 70.A SG SER 52.A OG no hydrogen 3.516 N/A GLY 71.A N VAL 78.A O no hydrogen 3.012 N/A GLU 73.A N TYR 76.A O no hydrogen 2.727 N/A TYR 76.A N GLU 73.A O no hydrogen 3.131 N/A ASN 77.A N GLU 39.A O no hydrogen 2.684 N/A VAL 78.A N GLY 71.A O no hydrogen 2.744 N/A MET 79.A N LYS 37.A O no hydrogen 3.010 N/A VAL 80.A N TRP 69.A O no hydrogen 2.878 N/A MET 81.A N ALA 35.A O no hydrogen 2.811 N/A GLU 82.A N THR 66.A O no hydrogen 2.969 N/A GLY 85.A N MET 135.A O no hydrogen 2.671 N/A SER 87.A N ASP 90.A OD2 no hydrogen 3.156 N/A SER 87.A OG ASP 131.A OD1 no hydrogen 3.303 N/A LEU 88.A N PHE 133.A O no hydrogen 2.895 N/A ASP 90.A N SER 87.A OG no hydrogen 3.275 N/A LEU 91.A N SER 87.A O no hydrogen 3.065 N/A PHE 92.A N LEU 88.A O no hydrogen 2.849 N/A ASN 93.A N GLU 89.A O no hydrogen 3.067 N/A PHE 94.A N ASP 90.A O no hydrogen 3.194 N/A CYS 95.A N LEU 91.A O no hydrogen 3.008 N/A CYS 95.A N PHE 92.A O no hydrogen 3.004 N/A CYS 95.A SG LEU 91.A O no hydrogen 3.383 N/A ARG 97.A N PHE 92.A O no hydrogen 2.853 N/A ARG 97.A NH1 GLU 89.A OE2 no hydrogen 3.005 N/A ARG 97.A NH1 ASN 93.A OD1 no hydrogen 2.820 N/A ARG 97.A NH2 TYR 204.A OH no hydrogen 2.706 N/A ARG 97.A NH2 GLY 208.A O no hydrogen 3.567 N/A LYS 98.A N CYS 95.A O no hydrogen 3.380 N/A PHE 99.A N PHE 205.A O no hydrogen 3.268 N/A SER 100.A N ASP 282.A OD2 no hydrogen 2.740 N/A SER 100.A OG ASP 282.A OD1 no hydrogen 2.797 N/A SER 100.A OG ASP 282.A OD2 no hydrogen 3.361 N/A LYS 102.A NZ SER 276.A O no hydrogen 3.404 N/A LYS 102.A NZ ASP 278.A OD1 no hydrogen 2.653 N/A LYS 102.A NZ ASP 278.A OD2 no hydrogen 3.358 N/A THR 103.A N SER 100.A OG no hydrogen 3.347 N/A VAL 104.A N SER 100.A O no hydrogen 3.045 N/A LEU 105.A N LEU 101.A O no hydrogen 2.935 N/A LEU 106.A N LYS 102.A O no hydrogen 2.904 N/A LEU 107.A N THR 103.A O no hydrogen 2.916 N/A ALA 108.A N VAL 104.A O no hydrogen 2.840 N/A ASP 109.A N LEU 105.A O no hydrogen 3.246 N/A GLN 110.A NE2 ASN 142.A O no hydrogen 3.194 N/A MET 111.A N LEU 107.A O no hydrogen 2.816 N/A ILE 112.A N ALA 108.A O no hydrogen 2.886 N/A SER 113.A N ASP 109.A O no hydrogen 2.992 N/A SER 113.A OG ASP 109.A O no hydrogen 3.212 N/A ARG 114.A N GLN 110.A O no hydrogen 2.871 N/A ARG 114.A NE VAL 144.A O no hydrogen 2.662 N/A ARG 114.A NH2 VAL 144.A O no hydrogen 3.365 N/A ILE 115.A N MET 111.A O no hydrogen 3.098 N/A GLU 116.A N ILE 112.A O no hydrogen 2.940 N/A TYR 117.A N SER 113.A O no hydrogen 2.999 N/A TYR 117.A OH MET 58.A O no hydrogen 3.101 N/A ILE 118.A N ARG 114.A O no hydrogen 3.184 N/A HIS 119.A N ILE 115.A O no hydrogen 3.173 N/A HIS 119.A ND1 TYR 259.A OH no hydrogen 2.707 N/A HIS 119.A NE2 ASP 194.A OD2 no hydrogen 2.856 N/A SER 120.A N GLU 116.A O no hydrogen 3.080 N/A SER 120.A OG TYR 117.A O no hydrogen 2.716 N/A LYS 121.A N TYR 117.A O no hydrogen 3.210 N/A LYS 121.A N ILE 118.A O no hydrogen 3.073 N/A ASN 122.A N HIS 119.A O no hydrogen 3.111 N/A PHE 123.A N ILE 118.A O no hydrogen 3.275 N/A ILE 124.A N LYS 153.A O no hydrogen 3.002 N/A HIS 125.A N ASP 194.A OD2 no hydrogen 2.985 N/A HIS 125.A NE2 ILE 147.A O no hydrogen 2.960 N/A ARG 126.A N ASP 194.A OD1 no hydrogen 3.020 N/A ARG 126.A NE LEU 151.A O no hydrogen 2.692 N/A ARG 126.A NH2 LEU 151.A O no hydrogen 2.965 N/A ASP 127.A N HIS 125.A ND1 no hydrogen 3.245 N/A LYS 129.A NZ ASP 127.A OD2 no hydrogen 3.274 N/A ASN 132.A N LYS 129.A O no hydrogen 2.947 N/A ASN 132.A ND2 ASP 127.A O no hydrogen 2.757 N/A PHE 133.A N PRO 130.A O no hydrogen 3.328 N/A LEU 134.A N TYR 145.A O no hydrogen 2.941 N/A MET 135.A N PRO 86.A O no hydrogen 3.094 N/A GLY 136.A N LEU 143.A O no hydrogen 3.007 N/A LYS 140.A N LEU 137.A O no hydrogen 2.840 N/A GLY 141.A N GLY 138.A O no hydrogen 3.117 N/A LEU 143.A N LYS 140.A O no hydrogen 2.918 N/A VAL 144.A N GLN 110.A OE1 no hydrogen 2.777 N/A TYR 145.A N LEU 134.A O no hydrogen 2.650 N/A ILE 146.A N GLY 63.A O no hydrogen 3.001 N/A ILE 147.A N ASN 132.A O no hydrogen 2.977 N/A ASP 148.A N TYR 55.A OH no hydrogen 2.718 N/A PHE 149.A N GLU 51.A OE2 no hydrogen 3.208 N/A GLY 150.A N ASP 148.A OD1 no hydrogen 3.128 N/A ALA 152.A N PHE 149.A O no hydrogen 3.176 N/A LYS 153.A N ILE 124.A O no hydrogen 3.023 N/A LYS 153.A NZ GLU 188.A OE2 no hydrogen 3.036 N/A TYR 155.A N ASN 122.A O no hydrogen 2.955 N/A TYR 155.A OH HIS 119.A O no hydrogen 2.520 N/A ARG 156.A NE ASN 122.A OD1 no hydrogen 2.574 N/A ARG 156.A NH2 SER 120.A O no hydrogen 3.445 N/A ARG 156.A NH2 ASN 122.A OD1 no hydrogen 3.079 N/A ASP 157.A N GLN 162.A O no hydrogen 3.064 N/A ARG 159.A N ASP 157.A OD2 no hydrogen 2.932 N/A THR 160.A N ASP 157.A OD2 no hydrogen 2.979 N/A THR 160.A OG1 ASP 157.A OD2 no hydrogen 3.353 N/A HIS 161.A N ASP 157.A O no hydrogen 2.862 N/A GLN 162.A N THR 160.A OG1 no hydrogen 3.052 N/A GLN 162.A NE2 HIS 163.A O no hydrogen 3.681 N/A HIS 163.A ND1 ILE 164.A O no hydrogen 2.876 N/A ILE 164.A N TYR 155.A O no hydrogen 2.736 N/A LYS 170.A N GLY 186.A O no hydrogen 2.882 N/A LYS 170.A NZ GLU 188.A OE2 no hydrogen 2.970 N/A THR 173.A OG1 GLN 189.A OE1 no hydrogen 2.842 N/A THR 175.A N ASP 127.A OD1 no hydrogen 3.089 N/A THR 175.A OG1 ASP 127.A OD1 no hydrogen 3.061 N/A ARG 177.A NH1 TYR 178.A OH no hydrogen 3.013 N/A ALA 179.A N ALA 176.A O no hydrogen 3.190 N/A SER 180.A OG THR 183.A OG1 no hydrogen 2.951 N/A SER 180.A OG ASP 193.A OD1 no hydrogen 2.623 N/A ILE 181.A N GLU 196.A OE2 no hydrogen 3.177 N/A THR 183.A N SER 180.A OG no hydrogen 2.990 N/A THR 183.A OG1 SER 180.A OG no hydrogen 2.951 N/A HIS 184.A N SER 180.A O no hydrogen 3.124 N/A LEU 185.A N ILE 181.A O no hydrogen 3.104 N/A GLY 186.A N THR 183.A O no hydrogen 3.126 N/A ILE 187.A N ASN 182.A O no hydrogen 2.948 N/A GLU 188.A N ARG 167.A O no hydrogen 3.002 N/A GLN 189.A NE2 ARG 126.A O no hydrogen 3.696 N/A SER 190.A N ASP 193.A OD2 no hydrogen 2.819 N/A SER 190.A OG ASP 193.A OD2 no hydrogen 3.424 N/A SER 190.A OG PHE 253.A O no hydrogen 2.761 N/A ARG 191.A NH2 ASP 254.A O no hydrogen 3.135 N/A ARG 192.A NH1 LEU 251.A O no hydrogen 2.982 N/A ASP 193.A N SER 190.A O no hydrogen 3.061 N/A ASP 194.A N ARG 191.A O no hydrogen 3.183 N/A LEU 195.A N ARG 191.A O no hydrogen 3.442 N/A GLU 196.A N ARG 192.A O no hydrogen 2.837 N/A SER 197.A N ASP 193.A O no hydrogen 3.107 N/A SER 197.A OG TYR 178.A O no hydrogen 2.572 N/A SER 197.A OG ASP 193.A O no hydrogen 3.165 N/A LEU 198.A N ASP 194.A O no hydrogen 3.140 N/A GLY 199.A N LEU 195.A O no hydrogen 3.136 N/A TYR 200.A N GLU 196.A O no hydrogen 3.254 N/A TYR 200.A OH GLU 196.A OE2 no hydrogen 2.658 N/A VAL 201.A N SER 197.A O no hydrogen 2.864 N/A LEU 202.A N LEU 198.A O no hydrogen 2.880 N/A MET 203.A N GLY 199.A O no hydrogen 3.117 N/A TYR 204.A N TYR 200.A O no hydrogen 2.864 N/A TYR 204.A OH GLU 89.A OE1 no hydrogen 2.934 N/A TYR 204.A OH GLU 89.A OE2 no hydrogen 3.071 N/A PHE 205.A N VAL 201.A O no hydrogen 3.097 N/A ASN 206.A N LEU 202.A O no hydrogen 3.063 N/A LEU 207.A N MET 203.A O no hydrogen 2.808 N/A GLY 208.A N TYR 204.A O no hydrogen 2.842 N/A LEU 210.A N GLN 213.A OE1 no hydrogen 2.945 N/A TRP 212.A NE1 ARG 177.A O no hydrogen 2.963 N/A GLN 213.A N LEU 210.A O no hydrogen 2.838 N/A ARG 220.A N GLN 216.A O no hydrogen 3.069 N/A ILE 221.A N LYS 217.A O no hydrogen 3.102 N/A SER 222.A N TYR 218.A O no hydrogen 3.106 N/A GLU 223.A N GLU 219.A O no hydrogen 3.034 N/A LYS 224.A N ARG 220.A O no hydrogen 3.164 N/A LYS 225.A N ILE 221.A O no hydrogen 2.737 N/A LYS 225.A NZ ALA 176.A O no hydrogen 2.940 N/A LYS 225.A NZ ARG 177.A O no hydrogen 3.330 N/A LYS 225.A NZ ALA 179.A O no hydrogen 2.679 N/A LYS 225.A NZ HIS 184.A NE2 no hydrogen 3.192 N/A MET 226.A N SER 222.A O no hydrogen 2.812 N/A SER 227.A N GLU 223.A O no hydrogen 2.600 N/A SER 227.A OG GLU 223.A O no hydrogen 3.050 N/A THR 228.A OG1 LYS 224.A O no hydrogen 2.650 N/A LEU 233.A N PRO 229.A O no hydrogen 2.859 N/A CYS 234.A N ILE 230.A O no hydrogen 2.823 N/A CYS 234.A SG ILE 230.A O no hydrogen 3.513 N/A LYS 235.A N VAL 232.A O no hydrogen 3.397 N/A TYR 237.A N CYS 234.A O no hydrogen 3.116 N/A GLU 240.A N GLU 240.A OE1 no hydrogen 2.623 N/A PHE 241.A N PRO 238.A O no hydrogen 3.209 N/A THR 243.A N SER 239.A O no hydrogen 2.905 N/A THR 243.A OG1 SER 239.A O no hydrogen 3.136 N/A TYR 244.A N GLU 240.A O no hydrogen 2.752 N/A TYR 244.A OH LEU 195.A O no hydrogen 2.820 N/A LEU 245.A N PHE 241.A O no hydrogen 3.253 N/A ASN 246.A N ALA 242.A O no hydrogen 2.852 N/A PHE 247.A N THR 243.A O no hydrogen 2.992 N/A CYS 248.A N TYR 244.A O no hydrogen 3.093 N/A CYS 248.A SG TYR 244.A O no hydrogen 3.447 N/A ARG 249.A N LEU 245.A O no hydrogen 3.022 N/A ARG 249.A NH2 TYR 200.A OH no hydrogen 2.876 N/A SER 250.A N ASN 246.A O no hydrogen 3.025 N/A SER 250.A N PHE 247.A O no hydrogen 2.995 N/A SER 250.A OG PHE 247.A O no hydrogen 2.586 N/A LEU 251.A N CYS 248.A O no hydrogen 3.168 N/A ARG 252.A N ASP 255.A OD2 no hydrogen 2.982 N/A ASP 255.A N ARG 252.A O no hydrogen 3.082 N/A TYR 259.A OH HIS 119.A ND1 no hydrogen 2.707 N/A TYR 261.A N ASP 258.A OD1 no hydrogen 3.014 N/A LEU 262.A N ASP 258.A O no hydrogen 3.297 N/A ARG 263.A N TYR 259.A O no hydrogen 2.950 N/A ARG 263.A NH1 SER 113.A OG no hydrogen 3.144 N/A ARG 263.A NH1 GLU 116.A OE1 no hydrogen 2.797 N/A ARG 263.A NH2 GLU 116.A OE1 no hydrogen 3.111 N/A GLN 264.A N SER 260.A O no hydrogen 2.834 N/A GLN 264.A NE2 ASN 268.A OD1 no hydrogen 3.531 N/A LEU 265.A N TYR 261.A O no hydrogen 3.038 N/A ARG 267.A N ARG 263.A O no hydrogen 2.885 N/A ARG 267.A NH2 ASP 109.A OD2 no hydrogen 3.436 N/A ASN 268.A N GLN 264.A O no hydrogen 2.826 N/A LEU 269.A N LEU 265.A O no hydrogen 3.220 N/A PHE 270.A N PHE 266.A O no hydrogen 2.886 N/A HIS 271.A N ARG 267.A O no hydrogen 3.113 N/A ARG 272.A N ASN 268.A O no hydrogen 2.990 N/A ARG 272.A NH2 GLU 240.A OE2 no hydrogen 3.017 N/A GLN 273.A N LEU 269.A O no hydrogen 3.034 N/A GLY 274.A N HIS 271.A O no hydrogen 3.046 N/A VAL 280.A N ASP 278.A OD1 no hydrogen 3.144 N/A PHE 281.A N ASN 284.A OD1 no hydrogen 2.941 N/A ASP 282.A N THR 103.A OG1 no hydrogen 2.935 N/A ASN 284.A N PHE 281.A O no hydrogen 2.916 N/A MET 285.A N PHE 281.A O no hydrogen 3.300 N/A MET 285.A N ASP 282.A O no hydrogen 3.007 N/A LEU 286.A N TRP 283.A O no hydrogen 3.364 N/A