Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5ih8_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): MET 1.A N ASP 4.A OD1 no hydrogen 3.014 N/A LEU 7.A N TYR 3.A O no hydrogen 3.030 N/A LYS 8.A N GLU 5.A O no hydrogen 3.043 N/A TYR 9.A N LEU 6.A O no hydrogen 3.054 N/A TYR 10.A N LEU 6.A O no hydrogen 2.930 N/A TYR 10.A OH HIS 67.A ND1 no hydrogen 2.799 N/A GLU 11.A N CYS 25.A O no hydrogen 2.904 N/A HIS 13.A N LEU 23.A O no hydrogen 2.788 N/A HIS 13.A NE2 GLU 11.A OE1 no hydrogen 2.834 N/A GLU 14.A N GLU 14.A OE1 no hydrogen 2.740 N/A ILE 16.A N VAL 21.A O no hydrogen 2.927 N/A GLY 17.A N VAL 21.A O no hydrogen 3.505 N/A LYS 20.A N ILE 37.A O no hydrogen 2.991 N/A VAL 21.A N GLY 17.A O no hydrogen 2.789 N/A LYS 22.A N ILE 35.A O no hydrogen 2.884 N/A LYS 22.A NZ THR 15.A OG1 no hydrogen 2.697 N/A LEU 23.A N GLU 14.A O no hydrogen 2.924 N/A ALA 24.A N VAL 33.A O no hydrogen 2.960 N/A CYS 25.A N GLU 11.A O no hydrogen 2.869 N/A CYS 25.A SG HIS 26.A O no hydrogen 3.743 N/A CYS 25.A SG GLU 31.A O no hydrogen 3.962 N/A HIS 26.A N GLU 31.A O no hydrogen 2.725 N/A HIS 26.A ND1 THR 29.A OG1 no hydrogen 2.734 N/A HIS 26.A NE2 HIS 291.A NE2 no hydrogen 2.871 N/A ILE 27.A N TYR 9.A O no hydrogen 2.948 N/A THR 29.A N HIS 26.A ND1 no hydrogen 3.331 N/A THR 29.A OG1 HIS 26.A ND1 no hydrogen 2.734 N/A GLY 30.A N HIS 26.A O no hydrogen 2.830 N/A GLU 31.A N THR 29.A OG1 no hydrogen 3.236 N/A VAL 33.A N ALA 24.A O no hydrogen 2.871 N/A ALA 34.A N LEU 79.A O no hydrogen 2.987 N/A ILE 35.A N LYS 22.A O no hydrogen 2.712 N/A LYS 36.A N MET 77.A O no hydrogen 2.864 N/A LYS 36.A NZ GLU 50.A OE1 no hydrogen 2.708 N/A LYS 36.A NZ GLU 50.A OE2 no hydrogen 3.486 N/A ILE 37.A N LYS 20.A O no hydrogen 2.743 N/A MET 38.A N ILE 75.A O no hydrogen 3.028 N/A LYS 40.A N ASN 73.A O no hydrogen 2.789 N/A LYS 40.A NZ GLU 70.A OE2 no hydrogen 2.752 N/A ASN 41.A N ASP 39.A OD1 no hydrogen 3.308 N/A ASN 41.A ND2 ASN 73.A OD1 no hydrogen 2.757 N/A ARG 46.A NH1 ASP 143.A OD2 no hydrogen 3.542 N/A ILE 47.A N LEU 44.A O no hydrogen 3.091 N/A LYS 48.A N LEU 44.A O no hydrogen 3.118 N/A THR 49.A N PRO 45.A O no hydrogen 2.863 N/A THR 49.A OG1 PRO 45.A O no hydrogen 2.706 N/A GLU 50.A N ARG 46.A O no hydrogen 3.159 N/A ILE 51.A N ILE 47.A O no hydrogen 2.952 N/A GLU 52.A N LYS 48.A O no hydrogen 2.961 N/A ALA 53.A N THR 49.A O no hydrogen 3.142 N/A LEU 54.A N GLU 50.A O no hydrogen 2.970 N/A LYS 55.A N ILE 51.A O no hydrogen 2.970 N/A ASN 56.A N ALA 53.A O no hydrogen 3.014 N/A ASN 56.A ND2 TYR 121.A OH no hydrogen 2.992 N/A LEU 57.A N ALA 53.A O no hydrogen 2.894 N/A ARG 58.A N TYR 115.A OH no hydrogen 3.009 N/A ARG 58.A NH1 PRO 257.A O no hydrogen 3.127 N/A ARG 58.A NH2 TYR 289.A OH no hydrogen 2.928 N/A HIS 59.A NE2 TRP 252.A O no hydrogen 2.798 N/A GLN 60.A N GLN 60.A OE1 no hydrogen 2.754 N/A GLN 60.A NE2 GLN 253.A O no hydrogen 3.060 N/A HIS 61.A N HIS 59.A ND1 no hydrogen 2.830 N/A HIS 61.A ND1 LEU 139.A O no hydrogen 2.857 N/A ILE 62.A N HIS 59.A O no hydrogen 3.057 N/A CYS 63.A N LEU 141.A O no hydrogen 2.990 N/A CYS 63.A SG GLU 80.A O no hydrogen 3.435 N/A GLN 64.A N GLU 80.A OE1 no hydrogen 2.922 N/A GLN 64.A NE2 LEU 65.A O no hydrogen 2.885 N/A TYR 66.A N VAL 78.A O no hydrogen 2.776 N/A HIS 67.A ND1 TYR 10.A OH no hydrogen 2.799 N/A VAL 68.A N TYR 289.A O no hydrogen 2.907 N/A LEU 69.A N PHE 76.A O no hydrogen 2.966 N/A THR 71.A N LYS 74.A O no hydrogen 2.793 N/A THR 71.A OG1 ASP 2.A OD1 no hydrogen 2.959 N/A THR 71.A OG1 LYS 74.A O no hydrogen 3.342 N/A LYS 74.A N THR 71.A OG1 no hydrogen 2.780 N/A LYS 74.A NZ ASP 39.A OD2 no hydrogen 2.801 N/A ILE 75.A N MET 38.A O no hydrogen 3.005 N/A PHE 76.A N LEU 69.A O no hydrogen 2.757 N/A MET 77.A N LYS 36.A O no hydrogen 2.911 N/A VAL 78.A N HIS 67.A O no hydrogen 2.800 N/A LEU 79.A N ALA 34.A O no hydrogen 2.737 N/A GLU 80.A N GLN 64.A O no hydrogen 2.896 N/A CYS 82.A SG GLU 80.A O no hydrogen 3.620 N/A GLY 84.A N PHE 133.A O no hydrogen 2.839 N/A LEU 87.A N LEU 131.A O no hydrogen 2.871 N/A PHE 88.A N PRO 128.A O no hydrogen 3.228 N/A TYR 90.A N GLU 86.A O no hydrogen 3.023 N/A TYR 90.A OH GLU 101.A OE2 no hydrogen 2.361 N/A ILE 91.A N LEU 87.A O no hydrogen 2.896 N/A ILE 92.A N PHE 88.A O no hydrogen 3.226 N/A SER 93.A N ASP 89.A O no hydrogen 2.932 N/A SER 93.A OG TYR 90.A O no hydrogen 2.603 N/A GLN 94.A N TYR 90.A O no hydrogen 3.049 N/A ASP 95.A N ILE 92.A O no hydrogen 3.049 N/A LEU 97.A N LEU 181.A O no hydrogen 2.884 N/A GLU 100.A N GLU 100.A OE1 no hydrogen 2.744 N/A GLU 101.A N SER 98.A OG no hydrogen 3.056 N/A THR 102.A N SER 98.A O no hydrogen 2.805 N/A THR 102.A OG1 SER 98.A O no hydrogen 2.873 N/A ARG 103.A N GLU 99.A O no hydrogen 2.924 N/A ARG 103.A NE TRP 241.A O no hydrogen 2.628 N/A ARG 103.A NH2 GLU 99.A OE2 no hydrogen 2.669 N/A ARG 103.A NH2 TRP 241.A O no hydrogen 3.201 N/A VAL 104.A N GLU 100.A O no hydrogen 3.214 N/A VAL 105.A N GLU 101.A O no hydrogen 3.253 N/A PHE 106.A N THR 102.A O no hydrogen 2.660 N/A ARG 107.A N ARG 103.A O no hydrogen 2.928 N/A ARG 107.A NH1 ILE 242.A O no hydrogen 2.973 N/A ARG 107.A NH1 TYR 248.A O no hydrogen 3.025 N/A ARG 107.A NH2 TYR 248.A O no hydrogen 3.209 N/A ARG 107.A NH2 PRO 249.A O no hydrogen 3.389 N/A GLN 108.A N VAL 105.A O no hydrogen 3.042 N/A GLN 108.A NE2 VAL 104.A O no hydrogen 3.137 N/A ILE 109.A N VAL 105.A O no hydrogen 3.164 N/A VAL 110.A N PHE 106.A O no hydrogen 2.851 N/A SER 111.A N ARG 107.A O no hydrogen 3.040 N/A SER 111.A OG GLU 251.A O no hydrogen 2.776 N/A ALA 112.A N GLN 108.A O no hydrogen 3.141 N/A VAL 113.A N ILE 109.A O no hydrogen 2.986 N/A ALA 114.A N VAL 110.A O no hydrogen 2.873 N/A TYR 115.A N SER 111.A O no hydrogen 3.210 N/A VAL 116.A N ALA 112.A O no hydrogen 2.982 N/A HIS 117.A N VAL 113.A O no hydrogen 2.967 N/A HIS 117.A NE2 ASP 170.A OD2 no hydrogen 2.730 N/A SER 118.A N ALA 114.A O no hydrogen 2.907 N/A SER 118.A OG TYR 115.A O no hydrogen 2.582 N/A GLN 119.A N TYR 115.A O no hydrogen 3.061 N/A GLN 119.A N VAL 116.A O no hydrogen 3.152 N/A GLY 120.A N HIS 117.A O no hydrogen 3.046 N/A TYR 121.A N VAL 116.A O no hydrogen 3.121 N/A TYR 121.A OH GLU 52.A OE1 no hydrogen 2.804 N/A ALA 122.A N ALA 148.A O no hydrogen 2.945 N/A HIS 123.A N ASP 170.A OD2 no hydrogen 2.881 N/A HIS 123.A NE2 ILE 142.A O no hydrogen 2.913 N/A ARG 124.A N ASP 170.A OD1 no hydrogen 2.875 N/A ARG 124.A NE LEU 146.A O no hydrogen 2.710 N/A ARG 124.A NH2 LEU 146.A O no hydrogen 2.918 N/A ASP 125.A N HIS 123.A ND1 no hydrogen 3.003 N/A LYS 127.A NZ SER 150.A OG no hydrogen 2.975 N/A GLU 129.A N GLU 129.A OE1 no hydrogen 2.769 N/A ASN 130.A N LYS 127.A O no hydrogen 2.957 N/A ASN 130.A ND2 ASP 125.A O no hydrogen 2.854 N/A ASN 130.A ND2 ASP 125.A OD2 no hydrogen 3.506 N/A LEU 131.A N PRO 128.A O no hydrogen 3.393 N/A LEU 132.A N LYS 140.A O no hydrogen 2.871 N/A PHE 133.A N GLY 85.A O no hydrogen 2.914 N/A ASP 134.A N LYS 138.A O no hydrogen 2.892 N/A TYR 136.A N ASP 134.A OD1 no hydrogen 2.912 N/A HIS 137.A N ASP 134.A O no hydrogen 3.036 N/A LYS 138.A N ASP 134.A OD1 no hydrogen 2.979 N/A LEU 139.A N GLN 108.A OE1 no hydrogen 2.810 N/A LYS 140.A N LEU 132.A O no hydrogen 2.697 N/A LYS 140.A NZ GLN 60.A O no hydrogen 2.826 N/A LYS 140.A NZ GLU 80.A OE2 no hydrogen 2.832 N/A LEU 141.A N HIS 61.A O no hydrogen 2.823 N/A ILE 142.A N ASN 130.A O no hydrogen 2.892 N/A PHE 144.A N GLU 50.A OE2 no hydrogen 3.061 N/A GLY 145.A N ASP 143.A OD1 no hydrogen 3.214 N/A CYS 147.A N PHE 144.A O no hydrogen 3.369 N/A CYS 147.A SG PHE 144.A O no hydrogen 3.443 N/A ALA 148.A N ALA 122.A O no hydrogen 2.925 N/A SER 150.A OG ASP 125.A OD1 no hydrogen 2.688 N/A TYR 153.A N SER 150.A O no hydrogen 2.993 N/A ALA 154.A N LEU 151.A O no hydrogen 3.097 N/A GLU 157.A N GLU 157.A OE1 no hydrogen 2.807 N/A LEU 158.A N ALA 155.A O no hydrogen 2.971 N/A ILE 159.A N ALA 155.A O no hydrogen 3.170 N/A GLN 160.A N PRO 156.A O no hydrogen 3.170 N/A LYS 162.A N GLU 157.A O no hydrogen 3.165 N/A ALA 169.A N LEU 165.A O no hydrogen 3.139 N/A ASP 170.A N GLY 166.A O no hydrogen 2.899 N/A VAL 171.A N SER 167.A O no hydrogen 3.107 N/A TRP 172.A N GLU 168.A O no hydrogen 3.153 N/A SER 173.A N ALA 169.A O no hydrogen 3.031 N/A SER 173.A OG TYR 153.A O no hydrogen 2.739 N/A SER 173.A OG ALA 169.A O no hydrogen 3.235 N/A MET 174.A N ASP 170.A O no hydrogen 2.872 N/A GLY 175.A N VAL 171.A O no hydrogen 3.059 N/A ILE 176.A N TRP 172.A O no hydrogen 3.068 N/A LEU 177.A N SER 173.A O no hydrogen 2.904 N/A LEU 178.A N MET 174.A O no hydrogen 2.846 N/A TYR 179.A N GLY 175.A O no hydrogen 3.029 N/A TYR 179.A OH ASP 206.A O no hydrogen 2.676 N/A VAL 180.A N ILE 176.A O no hydrogen 2.972 N/A LEU 181.A N LEU 177.A O no hydrogen 2.851 N/A MET 182.A N LEU 178.A O no hydrogen 3.296 N/A CYS 183.A N TYR 179.A O no hydrogen 2.822 N/A CYS 183.A SG TYR 179.A O no hydrogen 3.405 N/A GLY 184.A N VAL 180.A O no hydrogen 2.788 N/A ASN 192.A N ASP 190.A OD1 no hydrogen 2.979 N/A MET 194.A N ASN 192.A OD1 no hydrogen 2.829 N/A ALA 195.A N ASN 192.A OD1 no hydrogen 3.125 N/A LEU 196.A N ASN 192.A O no hydrogen 2.987 N/A TYR 197.A N VAL 193.A O no hydrogen 2.962 N/A LYS 198.A N MET 194.A O no hydrogen 3.000 N/A LYS 199.A N ALA 195.A O no hydrogen 3.065 N/A LYS 199.A NZ ASP 189.A O no hydrogen 2.761 N/A LYS 199.A NZ ASP 190.A OD2 no hydrogen 3.051 N/A ILE 200.A N LEU 196.A O no hydrogen 2.924 N/A MET 201.A N TYR 197.A O no hydrogen 3.060 N/A ARG 202.A N LYS 198.A O no hydrogen 3.040 N/A GLY 203.A N LYS 199.A O no hydrogen 3.091 N/A TRP 210.A NE1 MET 182.A O no hydrogen 2.864 N/A LEU 211.A N PRO 208.A O no hydrogen 3.199 N/A SER 212.A OG GLU 99.A OE1 no hydrogen 2.663 N/A SER 212.A OG SER 214.A OG no hydrogen 3.187 N/A SER 212.A OG SER 215.A OG no hydrogen 3.277 N/A SER 214.A OG SER 212.A OG no hydrogen 3.187 N/A SER 215.A N SER 212.A OG no hydrogen 3.236 N/A SER 215.A OG SER 212.A OG no hydrogen 3.277 N/A ILE 216.A N SER 212.A O no hydrogen 3.091 N/A LEU 217.A N PRO 213.A O no hydrogen 3.083 N/A LEU 218.A N SER 214.A O no hydrogen 3.066 N/A LEU 219.A N SER 215.A O no hydrogen 2.969 N/A GLN 220.A N ILE 216.A O no hydrogen 3.026 N/A GLN 221.A N LEU 217.A O no hydrogen 3.026 N/A MET 222.A N LEU 218.A O no hydrogen 3.109 N/A MET 222.A N LEU 219.A O no hydrogen 3.173 N/A LEU 223.A N LEU 219.A O no hydrogen 2.722 N/A GLN 224.A NE2 GLN 220.A O no hydrogen 2.760 N/A LYS 228.A N ASP 226.A OD1 no hydrogen 3.079 N/A LYS 228.A NZ GLU 168.A OE2 no hydrogen 3.282 N/A LYS 229.A N ASP 226.A O no hydrogen 2.978 N/A ARG 230.A N PRO 227.A O no hydrogen 3.330 N/A ARG 230.A NE GLN 224.A O no hydrogen 2.635 N/A ARG 230.A NH1 GLU 157.A OE2 no hydrogen 2.791 N/A ARG 230.A NH1 GLU 168.A O no hydrogen 3.028 N/A ARG 230.A NH2 GLU 157.A OE1 no hydrogen 2.754 N/A ARG 230.A NH2 GLU 157.A OE2 no hydrogen 3.510 N/A ARG 230.A NH2 GLN 224.A O no hydrogen 3.149 N/A ARG 230.A NH2 VAL 225.A O no hydrogen 3.082 N/A ILE 231.A N GLN 221.A O no hydrogen 3.000 N/A LYS 234.A NZ LYS 234.A O no hydrogen 3.528 N/A ASN 235.A N SER 232.A OG no hydrogen 3.238 N/A LEU 236.A N SER 232.A O no hydrogen 3.126 N/A LEU 236.A N MET 233.A O no hydrogen 3.008 N/A LEU 237.A N MET 233.A O no hydrogen 3.170 N/A HIS 239.A N LEU 236.A O no hydrogen 3.318 N/A HIS 239.A NE2 GLN 221.A OE1 no hydrogen 2.652 N/A TRP 241.A N HIS 239.A ND1 no hydrogen 2.950 N/A TRP 241.A NE1 SER 215.A OG no hydrogen 2.983 N/A MET 243.A N HIS 239.A O no hydrogen 2.898 N/A GLN 244.A N PRO 240.A O no hydrogen 3.074 N/A GLN 244.A NE2 ASP 245.A OD1 no hydrogen 2.934 N/A TYR 246.A N MET 243.A O no hydrogen 2.900 N/A ASN 247.A N MET 243.A O no hydrogen 2.733 N/A VAL 250.A N LEU 237.A O no hydrogen 2.917 N/A SER 254.A OG ARG 58.A O no hydrogen 2.664 N/A SER 254.A OG ASN 256.A O no hydrogen 3.186 N/A LYS 255.A N GLN 60.A OE1 no hydrogen 2.904 N/A ASN 256.A N SER 254.A OG no hydrogen 2.939 N/A ASP 262.A N TYR 296.A OH no hydrogen 2.765 N/A CYS 265.A N ASP 262.A OD1 no hydrogen 2.946 N/A CYS 265.A SG ASP 262.A OD1 no hydrogen 3.407 N/A VAL 266.A N ASP 262.A O no hydrogen 2.994 N/A THR 267.A N ASP 263.A O no hydrogen 3.009 N/A THR 267.A OG1 ASP 263.A O no hydrogen 3.159 N/A GLU 268.A N ASP 264.A O no hydrogen 2.992 N/A LEU 269.A N CYS 265.A O no hydrogen 2.907 N/A SER 270.A N VAL 266.A O no hydrogen 2.834 N/A SER 270.A OG VAL 266.A O no hydrogen 2.698 N/A HIS 272.A N LEU 269.A O no hydrogen 3.076 N/A HIS 273.A N SER 270.A O no hydrogen 3.102 N/A HIS 273.A ND1 LEU 269.A O no hydrogen 3.198 N/A ARG 277.A NH1 ASP 263.A O no hydrogen 2.901 N/A ARG 277.A NH1 THR 267.A OG1 no hydrogen 2.898 N/A ARG 277.A NH2 THR 267.A OG1 no hydrogen 2.673 N/A THR 279.A N ASN 276.A OD1 no hydrogen 2.905 N/A THR 279.A OG1 ASN 276.A OD1 no hydrogen 3.072 N/A MET 280.A N ASN 276.A O no hydrogen 3.097 N/A GLU 281.A N ARG 277.A O no hydrogen 2.969 N/A ASP 282.A N GLN 278.A O no hydrogen 3.093 N/A LEU 283.A N THR 279.A O no hydrogen 2.990 N/A ILE 284.A N MET 280.A O no hydrogen 2.813 N/A SER 285.A N GLU 281.A O no hydrogen 3.010 N/A SER 285.A OG GLU 281.A O no hydrogen 2.971 N/A LEU 286.A N LEU 283.A O no hydrogen 3.126 N/A TRP 287.A N ILE 284.A O no hydrogen 2.947 N/A TRP 287.A NE1 PHE 258.A O no hydrogen 2.885 N/A TYR 289.A N THR 293.A OG1 no hydrogen 2.971 N/A TYR 289.A OH LYS 55.A O no hydrogen 2.869 N/A HIS 291.A NE2 HIS 26.A NE2 no hydrogen 2.871 N/A THR 293.A N ASP 290.A OD1 no hydrogen 3.230 N/A THR 293.A OG1 ASP 290.A OD1 no hydrogen 3.375 N/A ALA 294.A N ASP 290.A O no hydrogen 3.159 N/A THR 295.A N HIS 291.A O no hydrogen 2.864 N/A THR 295.A OG1 HIS 291.A O no hydrogen 2.835 N/A TYR 296.A N LEU 292.A O no hydrogen 3.005 N/A LEU 297.A N THR 293.A O no hydrogen 3.047 N/A LEU 298.A N ALA 294.A O no hydrogen 2.915 N/A LEU 299.A N THR 295.A O no hydrogen 2.993 N/A LEU 300.A N TYR 296.A O no hydrogen 3.014 N/A ALA 301.A N LEU 297.A O no hydrogen 3.009 N/A LYS 302.A N LEU 298.A O no hydrogen 2.830 N/A LYS 302.A NZ THR 29.A O no hydrogen 3.226 N/A LYS 303.A N LEU 299.A O no hydrogen 2.909 N/A LYS 303.A NZ ASP 262.A OD1 no hydrogen 3.099 N/A LYS 303.A NZ ASP 262.A OD2 no hydrogen 2.683 N/A LYS 303.A NZ ASP 264.A OD2 no hydrogen 2.905 N/A ALA 304.A N LEU 300.A O no hydrogen 2.948 N/A ARG 305.A N ALA 301.A O no hydrogen 3.316 N/A ARG 305.A N LYS 302.A O no hydrogen 3.273 N/A ARG 305.A NE GLU 135.A OE2 no hydrogen 2.806 N/A ARG 305.A NH1 GLU 31.A OE1 no hydrogen 3.446 N/A ARG 305.A NH1 GLU 31.A OE2 no hydrogen 2.766 N/A ARG 305.A NH2 GLU 31.A OE1 no hydrogen 2.790 N/A ARG 305.A NH2 GLU 135.A OE1 no hydrogen 3.281 N/A GLY 306.A N LYS 303.A O no hydrogen 3.043 N/A