Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5ih9_A.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): ASP 4.A N MET 1.A O no hydrogen 3.314 N/A LEU 7.A N TYR 3.A O no hydrogen 2.879 N/A LYS 8.A N GLU 5.A O no hydrogen 3.097 N/A TYR 9.A N LEU 6.A O no hydrogen 3.009 N/A TYR 10.A N LEU 6.A O no hydrogen 2.978 N/A TYR 10.A OH HIS 69.A ND1 no hydrogen 2.748 N/A GLU 11.A N CYS 28.A O no hydrogen 2.903 N/A HIS 13.A N LEU 26.A O no hydrogen 2.788 N/A GLU 14.A N GLU 14.A OE1 no hydrogen 2.756 N/A ILE 16.A N VAL 24.A O no hydrogen 2.908 N/A THR 18.A OG1 ALA 22.A O no hydrogen 3.251 N/A LYS 23.A N ILE 40.A O no hydrogen 2.963 N/A LYS 25.A N ILE 38.A O no hydrogen 2.776 N/A LYS 25.A NZ THR 15.A OG1 no hydrogen 2.970 N/A LEU 26.A N GLU 14.A O no hydrogen 2.784 N/A ALA 27.A N VAL 36.A O no hydrogen 3.037 N/A CYS 28.A N GLU 11.A O no hydrogen 3.006 N/A CYS 28.A SG.A GLU 11.A O no hydrogen 4.020 N/A CYS 28.A SG.A HIS 13.A NE2 no hydrogen 3.877 N/A CYS 28.A SG.B GLY 33.A O no hydrogen 3.167 N/A CYS 28.A SG.B GLU 34.A O no hydrogen 3.985 N/A HIS 29.A N GLU 34.A O no hydrogen 2.772 N/A HIS 29.A ND1 THR 32.A OG1 no hydrogen 2.758 N/A HIS 29.A NE2 HIS 293.A NE2 no hydrogen 2.847 N/A ILE 30.A N TYR 9.A O no hydrogen 2.858 N/A THR 32.A N HIS 29.A ND1 no hydrogen 3.326 N/A THR 32.A OG1 HIS 29.A ND1 no hydrogen 2.758 N/A GLY 33.A N HIS 29.A O no hydrogen 2.784 N/A GLU 34.A N THR 32.A OG1 no hydrogen 3.167 N/A VAL 36.A N ALA 27.A O no hydrogen 2.827 N/A ALA 37.A N LEU 81.A O no hydrogen 2.987 N/A ILE 38.A N LYS 25.A O no hydrogen 2.758 N/A LYS 39.A N MET 79.A O no hydrogen 2.858 N/A LYS 39.A NZ GLU 52.A OE1 no hydrogen 2.587 N/A LYS 39.A NZ GLU 52.A OE2 no hydrogen 3.285 N/A ILE 40.A N LYS 23.A O no hydrogen 2.764 N/A MET 41.A N ILE 77.A O no hydrogen 2.986 N/A LYS 43.A N ASN 75.A O no hydrogen 2.677 N/A LYS 43.A NZ GLU 72.A OE2 no hydrogen 2.846 N/A LYS 43.A NZ THR 73.A O no hydrogen 2.822 N/A THR 45.A N ASP 42.A O no hydrogen 3.223 N/A THR 45.A OG1 ASP 42.A OD2 no hydrogen 2.870 N/A LYS 50.A N LEU 46.A O no hydrogen 3.207 N/A LYS 50.A NZ GLU 72.A OE1 no hydrogen 3.374 N/A THR 51.A N PRO 47.A O no hydrogen 2.871 N/A THR 51.A OG1 ARG 48.A O no hydrogen 2.848 N/A THR 51.A OG1 GLY 147.A O no hydrogen 2.679 N/A GLU 52.A N ARG 48.A O no hydrogen 3.066 N/A ILE 53.A N ILE 49.A O no hydrogen 2.953 N/A GLU 54.A N LYS 50.A O no hydrogen 3.064 N/A ALA 55.A N THR 51.A O no hydrogen 3.095 N/A LEU 56.A N GLU 52.A O no hydrogen 2.944 N/A LYS 57.A N ILE 53.A O no hydrogen 2.986 N/A ASN 58.A N ALA 55.A O no hydrogen 2.946 N/A ASN 58.A ND2 GLU 54.A O no hydrogen 2.816 N/A ARG 60.A N TYR 117.A OH no hydrogen 2.991 N/A ARG 60.A NH1 PRO 259.A O no hydrogen 3.076 N/A ARG 60.A NH2 TYR 291.A OH no hydrogen 2.961 N/A HIS 61.A NE2 TRP 254.A O no hydrogen 2.781 N/A GLN 62.A N GLN 62.A OE1 no hydrogen 2.744 N/A GLN 62.A NE2 GLN 255.A O no hydrogen 3.029 N/A HIS 63.A N HIS 61.A ND1 no hydrogen 2.842 N/A HIS 63.A ND1 LEU 141.A O no hydrogen 2.800 N/A ILE 64.A N HIS 61.A O no hydrogen 3.062 N/A CYS 65.A N LEU 143.A O no hydrogen 2.996 N/A CYS 65.A SG GLU 82.A O no hydrogen 3.421 N/A GLN 66.A N GLU 82.A OE1 no hydrogen 2.924 N/A GLN 66.A NE2 LEU 67.A O no hydrogen 2.785 N/A TYR 68.A N VAL 80.A O no hydrogen 2.794 N/A HIS 69.A ND1 TYR 10.A OH no hydrogen 2.748 N/A VAL 70.A N TYR 291.A O no hydrogen 2.954 N/A LEU 71.A N PHE 78.A O no hydrogen 3.037 N/A THR 73.A N LYS 76.A O no hydrogen 2.826 N/A THR 73.A OG1 ASP 2.A OD1 no hydrogen 3.020 N/A THR 73.A OG1 LYS 76.A O no hydrogen 3.380 N/A ASN 75.A ND2 ASP 2.A OD1 no hydrogen 2.852 N/A ASN 75.A ND2 ASP 2.A OD2 no hydrogen 2.972 N/A LYS 76.A N THR 73.A OG1 no hydrogen 2.965 N/A ILE 77.A N MET 41.A O no hydrogen 3.028 N/A PHE 78.A N LEU 71.A O no hydrogen 2.787 N/A MET 79.A N LYS 39.A O no hydrogen 2.854 N/A VAL 80.A N HIS 69.A O no hydrogen 2.764 N/A LEU 81.A N ALA 37.A O no hydrogen 2.670 N/A GLU 82.A N GLN 66.A O no hydrogen 2.911 N/A CYS 84.A SG GLU 82.A O no hydrogen 3.516 N/A GLY 86.A N PHE 135.A O no hydrogen 2.815 N/A LEU 89.A N LEU 133.A O no hydrogen 2.791 N/A PHE 90.A N PRO 130.A O no hydrogen 3.278 N/A TYR 92.A N GLU 88.A O no hydrogen 3.168 N/A TYR 92.A OH GLU 103.A OE2 no hydrogen 2.386 N/A ILE 93.A N LEU 89.A O no hydrogen 2.959 N/A ILE 94.A N PHE 90.A O no hydrogen 3.319 N/A SER 95.A N ASP 91.A O no hydrogen 2.985 N/A SER 95.A OG TYR 92.A O no hydrogen 2.665 N/A GLN 96.A N TYR 92.A O no hydrogen 3.123 N/A GLN 96.A N ILE 93.A O no hydrogen 3.087 N/A ASP 97.A N ILE 94.A O no hydrogen 3.021 N/A LEU 99.A N LEU 183.A O no hydrogen 2.893 N/A GLU 103.A N SER 100.A OG no hydrogen 3.092 N/A THR 104.A N SER 100.A O no hydrogen 2.860 N/A THR 104.A OG1 LEU 99.A O no hydrogen 3.568 N/A THR 104.A OG1 SER 100.A O no hydrogen 2.883 N/A ARG 105.A N GLU 101.A O no hydrogen 2.893 N/A ARG 105.A NE TRP 243.A O no hydrogen 2.612 N/A ARG 105.A NH2 GLU 101.A OE2 no hydrogen 2.735 N/A ARG 105.A NH2 TRP 243.A O no hydrogen 3.174 N/A VAL 106.A N GLU 102.A O no hydrogen 3.161 N/A VAL 107.A N GLU 103.A O no hydrogen 3.204 N/A PHE 108.A N THR 104.A O no hydrogen 2.677 N/A ARG 109.A N ARG 105.A O no hydrogen 2.998 N/A ARG 109.A NH1 ILE 244.A O no hydrogen 2.931 N/A ARG 109.A NH1 TYR 250.A O no hydrogen 3.138 N/A ARG 109.A NH2 TYR 250.A O no hydrogen 3.214 N/A ARG 109.A NH2 PRO 251.A O no hydrogen 3.427 N/A GLN 110.A N VAL 107.A O no hydrogen 3.046 N/A GLN 110.A NE2 VAL 106.A O no hydrogen 3.199 N/A ILE 111.A N VAL 107.A O no hydrogen 3.268 N/A VAL 112.A N PHE 108.A O no hydrogen 2.928 N/A SER 113.A N ARG 109.A O no hydrogen 3.016 N/A SER 113.A OG GLU 253.A O no hydrogen 2.776 N/A ALA 114.A N GLN 110.A O no hydrogen 3.099 N/A VAL 115.A N ILE 111.A O no hydrogen 2.913 N/A ALA 116.A N VAL 112.A O no hydrogen 2.807 N/A TYR 117.A N SER 113.A O no hydrogen 3.205 N/A VAL 118.A N ALA 114.A O no hydrogen 2.973 N/A HIS 119.A N VAL 115.A O no hydrogen 2.962 N/A HIS 119.A NE2 ASP 172.A OD2 no hydrogen 2.783 N/A SER 120.A N ALA 116.A O no hydrogen 2.896 N/A SER 120.A OG TYR 117.A O no hydrogen 2.632 N/A GLN 121.A N TYR 117.A O no hydrogen 3.040 N/A GLN 121.A N VAL 118.A O no hydrogen 3.152 N/A GLN 121.A NE2 ASN 58.A O no hydrogen 3.162 N/A GLY 122.A N HIS 119.A O no hydrogen 3.048 N/A TYR 123.A N VAL 118.A O no hydrogen 3.146 N/A TYR 123.A OH GLU 54.A OE1 no hydrogen 2.898 N/A TYR 123.A OH GLU 54.A OE2 no hydrogen 3.176 N/A ALA 124.A N ALA 150.A O no hydrogen 2.992 N/A HIS 125.A N ASP 172.A OD2 no hydrogen 2.866 N/A HIS 125.A NE2 ILE 144.A O no hydrogen 2.896 N/A ARG 126.A N ASP 172.A OD1 no hydrogen 2.865 N/A ARG 126.A NE LEU 148.A O no hydrogen 2.710 N/A ARG 126.A NH2 LEU 148.A O no hydrogen 2.941 N/A ASP 127.A N HIS 125.A ND1 no hydrogen 2.966 N/A LYS 129.A NZ SER 152.A OG no hydrogen 3.361 N/A GLU 131.A N GLU 131.A OE1 no hydrogen 2.680 N/A ASN 132.A N LYS 129.A O no hydrogen 3.001 N/A ASN 132.A ND2 ASP 127.A O no hydrogen 2.815 N/A LEU 133.A N PRO 130.A O no hydrogen 3.384 N/A LEU 134.A N LYS 142.A O no hydrogen 2.927 N/A PHE 135.A N GLY 87.A O no hydrogen 2.877 N/A ASP 136.A N LYS 140.A O no hydrogen 2.877 N/A TYR 138.A N ASP 136.A OD1 no hydrogen 2.843 N/A HIS 139.A N ASP 136.A O no hydrogen 3.037 N/A LYS 140.A N ASP 136.A OD1 no hydrogen 2.910 N/A LEU 141.A N GLN 110.A OE1 no hydrogen 2.805 N/A LYS 142.A N LEU 134.A O no hydrogen 2.762 N/A LYS 142.A NZ GLN 62.A O no hydrogen 2.786 N/A LYS 142.A NZ GLU 82.A OE2 no hydrogen 2.871 N/A LEU 143.A N HIS 63.A O no hydrogen 2.839 N/A ILE 144.A N ASN 132.A O no hydrogen 2.872 N/A PHE 146.A N GLU 52.A OE2 no hydrogen 3.091 N/A GLY 147.A N ASP 145.A OD1 no hydrogen 3.247 N/A CYS 149.A N PHE 146.A O no hydrogen 3.281 N/A CYS 149.A SG PHE 146.A O no hydrogen 3.334 N/A ALA 150.A N ALA 124.A O no hydrogen 3.040 N/A LYS 151.A NZ GLN 121.A O no hydrogen 3.170 N/A SER 152.A OG ASP 127.A OD1 no hydrogen 2.593 N/A TYR 155.A N SER 152.A O no hydrogen 3.121 N/A ALA 156.A N LEU 153.A O no hydrogen 3.079 N/A GLU 159.A N GLU 159.A OE1 no hydrogen 2.769 N/A LEU 160.A N ALA 157.A O no hydrogen 3.044 N/A ILE 161.A N ALA 157.A O no hydrogen 3.246 N/A GLN 162.A N PRO 158.A O no hydrogen 3.256 N/A GLN 162.A NE2 PRO 158.A O no hydrogen 3.229 N/A GLY 163.A N LEU 160.A O no hydrogen 3.282 N/A LYS 164.A N GLU 159.A O no hydrogen 3.110 N/A ALA 171.A N LEU 167.A O no hydrogen 3.131 N/A ASP 172.A N GLY 168.A O no hydrogen 2.905 N/A VAL 173.A N SER 169.A O no hydrogen 3.064 N/A TRP 174.A N GLU 170.A O no hydrogen 3.128 N/A SER 175.A N ALA 171.A O no hydrogen 3.053 N/A SER 175.A OG TYR 155.A O no hydrogen 2.725 N/A SER 175.A OG ALA 171.A O no hydrogen 3.178 N/A MET 176.A N ASP 172.A O no hydrogen 2.883 N/A GLY 177.A N VAL 173.A O no hydrogen 3.040 N/A ILE 178.A N TRP 174.A O no hydrogen 3.087 N/A LEU 179.A N SER 175.A O no hydrogen 2.977 N/A LEU 180.A N MET 176.A O no hydrogen 2.818 N/A TYR 181.A N GLY 177.A O no hydrogen 3.062 N/A TYR 181.A OH ASP 208.A O no hydrogen 2.696 N/A VAL 182.A N ILE 178.A O no hydrogen 2.951 N/A LEU 183.A N LEU 179.A O no hydrogen 2.835 N/A MET 184.A N LEU 180.A O no hydrogen 3.160 N/A CYS 185.A N TYR 181.A O no hydrogen 2.847 N/A GLY 186.A N VAL 182.A O no hydrogen 2.814 N/A ASN 194.A N ASP 192.A OD1 no hydrogen 2.894 N/A ALA 197.A N ASN 194.A OD1 no hydrogen 3.077 N/A LEU 198.A N ASN 194.A O no hydrogen 3.019 N/A TYR 199.A N VAL 195.A O no hydrogen 2.944 N/A LYS 200.A N MET 196.A O no hydrogen 3.017 N/A LYS 201.A N ALA 197.A O no hydrogen 2.988 N/A LYS 201.A NZ ASP 191.A O no hydrogen 2.817 N/A LYS 201.A NZ ASP 192.A OD2 no hydrogen 2.801 N/A ILE 202.A N LEU 198.A O no hydrogen 2.925 N/A MET 203.A N TYR 199.A O no hydrogen 3.064 N/A ARG 204.A N LYS 200.A O no hydrogen 3.045 N/A GLY 205.A N LYS 201.A O no hydrogen 3.052 N/A TRP 212.A NE1 MET 184.A O no hydrogen 2.837 N/A LEU 213.A N PRO 210.A O no hydrogen 3.228 N/A SER 214.A OG GLU 101.A OE1 no hydrogen 2.602 N/A SER 214.A OG SER 216.A OG.A no hydrogen 3.172 N/A SER 214.A OG SER 217.A OG no hydrogen 3.235 N/A SER 216.A OG.A SER 214.A OG no hydrogen 3.172 N/A SER 217.A N SER 214.A OG no hydrogen 3.148 N/A SER 217.A OG SER 214.A OG no hydrogen 3.235 N/A ILE 218.A N SER 214.A O no hydrogen 3.069 N/A LEU 219.A N PRO 215.A O no hydrogen 3.004 N/A LEU 220.A N SER 216.A O no hydrogen 3.000 N/A LEU 221.A N SER 217.A O no hydrogen 2.985 N/A GLN 222.A N ILE 218.A O no hydrogen 2.979 N/A GLN 223.A N LEU 219.A O no hydrogen 3.083 N/A MET 224.A N LEU 220.A O no hydrogen 3.157 N/A MET 224.A N LEU 221.A O no hydrogen 3.297 N/A LEU 225.A N LEU 221.A O no hydrogen 2.888 N/A GLN 226.A NE2 GLN 222.A O no hydrogen 2.759 N/A LYS 230.A N ASP 228.A OD1 no hydrogen 3.054 N/A LYS 231.A N ASP 228.A O no hydrogen 2.934 N/A ARG 232.A N PRO 229.A O no hydrogen 3.351 N/A ARG 232.A NE GLN 226.A O no hydrogen 2.811 N/A ARG 232.A NH1 GLU 159.A OE1 no hydrogen 3.568 N/A ARG 232.A NH1 GLU 159.A OE2 no hydrogen 2.712 N/A ARG 232.A NH1 GLU 170.A O no hydrogen 2.946 N/A ARG 232.A NH2 GLU 159.A OE1 no hydrogen 2.681 N/A ARG 232.A NH2 GLU 159.A OE2 no hydrogen 3.414 N/A ARG 232.A NH2 GLN 226.A O no hydrogen 3.223 N/A ARG 232.A NH2 VAL 227.A O no hydrogen 3.131 N/A ILE 233.A N GLN 223.A O no hydrogen 2.904 N/A ASN 237.A N SER 234.A OG no hydrogen 3.153 N/A LEU 238.A N SER 234.A O no hydrogen 3.130 N/A LEU 238.A N MET 235.A O no hydrogen 3.107 N/A LEU 239.A N MET 235.A O no hydrogen 3.203 N/A LEU 239.A N LYS 236.A O no hydrogen 3.322 N/A HIS 241.A N LEU 238.A O no hydrogen 3.290 N/A HIS 241.A NE2 GLN 223.A OE1 no hydrogen 2.704 N/A TRP 243.A N HIS 241.A ND1 no hydrogen 2.971 N/A TRP 243.A NE1 SER 217.A OG no hydrogen 2.883 N/A MET 245.A N HIS 241.A O no hydrogen 2.964 N/A GLN 246.A N TRP 243.A O no hydrogen 3.389 N/A GLN 246.A NE2 ASP 247.A OD1 no hydrogen 3.005 N/A TYR 248.A N MET 245.A O no hydrogen 2.905 N/A ASN 249.A N MET 245.A O no hydrogen 2.804 N/A VAL 252.A N LEU 239.A O no hydrogen 2.968 N/A SER 256.A OG ARG 60.A O no hydrogen 2.680 N/A SER 256.A OG ASN 258.A O no hydrogen 3.182 N/A LYS 257.A N GLN 62.A OE1 no hydrogen 2.876 N/A ASN 258.A N SER 256.A OG no hydrogen 2.919 N/A ASP 264.A N TYR 298.A OH no hydrogen 2.792 N/A CYS 267.A N ASP 264.A OD1 no hydrogen 3.132 N/A CYS 267.A SG ASP 264.A OD1 no hydrogen 3.522 N/A VAL 268.A N ASP 264.A O no hydrogen 3.033 N/A THR 269.A N ASP 265.A O no hydrogen 2.908 N/A THR 269.A OG1 ASP 265.A O no hydrogen 3.020 N/A GLU 270.A N ASP 266.A O no hydrogen 2.904 N/A LEU 271.A N CYS 267.A O no hydrogen 2.923 N/A SER 272.A N VAL 268.A O no hydrogen 2.937 N/A SER 272.A OG VAL 268.A O no hydrogen 2.688 N/A HIS 274.A N LEU 271.A O no hydrogen 3.060 N/A HIS 275.A N SER 272.A O no hydrogen 3.149 N/A ARG 276.A NH1 HIS 275.A O no hydrogen 2.956 N/A ARG 279.A NE GLU 283.A OE2 no hydrogen 3.309 N/A ARG 279.A NH1 ASP 265.A O no hydrogen 2.923 N/A ARG 279.A NH1 THR 269.A OG1 no hydrogen 3.274 N/A ARG 279.A NH2 THR 269.A OG1 no hydrogen 2.864 N/A GLN 280.A NE2 GLN 280.A O no hydrogen 3.292 N/A GLN 280.A NE2 ASP 284.A OD1 no hydrogen 2.985 N/A THR 281.A N ASN 278.A OD1 no hydrogen 2.898 N/A THR 281.A OG1 ASN 278.A OD1 no hydrogen 2.890 N/A MET 282.A N ASN 278.A O no hydrogen 3.056 N/A GLU 283.A N ARG 279.A O no hydrogen 3.009 N/A ASP 284.A N GLN 280.A O no hydrogen 2.931 N/A LEU 285.A N THR 281.A O no hydrogen 2.908 N/A ILE 286.A N MET 282.A O no hydrogen 3.008 N/A SER 287.A N GLU 283.A O no hydrogen 2.962 N/A SER 287.A OG GLU 283.A O no hydrogen 2.860 N/A LEU 288.A N LEU 285.A O no hydrogen 3.247 N/A TRP 289.A N ILE 286.A O no hydrogen 3.013 N/A TRP 289.A NE1 PHE 260.A O no hydrogen 2.916 N/A TYR 291.A N THR 295.A OG1 no hydrogen 2.891 N/A TYR 291.A OH LYS 57.A O no hydrogen 2.870 N/A HIS 293.A NE2 HIS 29.A NE2 no hydrogen 2.847 N/A THR 295.A N ASP 292.A OD1 no hydrogen 3.206 N/A THR 295.A OG1 ASP 292.A OD1 no hydrogen 3.392 N/A ALA 296.A N ASP 292.A O no hydrogen 3.188 N/A THR 297.A N HIS 293.A O no hydrogen 2.878 N/A THR 297.A OG1 HIS 29.A NE2 no hydrogen 3.406 N/A THR 297.A OG1 HIS 293.A O no hydrogen 2.846 N/A TYR 298.A N LEU 294.A O no hydrogen 2.970 N/A LEU 299.A N THR 295.A O no hydrogen 2.965 N/A LEU 300.A N ALA 296.A O no hydrogen 2.964 N/A LEU 301.A N THR 297.A O no hydrogen 2.951 N/A LEU 302.A N TYR 298.A O no hydrogen 3.072 N/A ALA 303.A N LEU 299.A O no hydrogen 2.996 N/A LYS 304.A N LEU 300.A O no hydrogen 2.870 N/A LYS 304.A NZ THR 32.A O no hydrogen 2.929 N/A LYS 305.A N LEU 301.A O no hydrogen 2.961 N/A LYS 305.A NZ ASP 264.A OD1 no hydrogen 3.061 N/A LYS 305.A NZ ASP 264.A OD2 no hydrogen 2.685 N/A LYS 305.A NZ ASP 266.A OD2 no hydrogen 2.989 N/A ALA 306.A N LEU 302.A O no hydrogen 2.946 N/A ARG 307.A N ALA 303.A O no hydrogen 3.237 N/A ARG 307.A NE GLU 137.A OE1 no hydrogen 3.477 N/A ARG 307.A NE GLU 137.A OE2 no hydrogen 2.939 N/A ARG 307.A NH1 GLU 34.A OE1 no hydrogen 3.431 N/A ARG 307.A NH1 GLU 34.A OE2 no hydrogen 2.759 N/A ARG 307.A NH2 GLU 34.A OE1 no hydrogen 2.724 N/A ARG 307.A NH2 GLU 137.A OE1 no hydrogen 3.056 N/A GLY 308.A N LYS 305.A O no hydrogen 2.994 N/A