Finding intermodel H-bonds Finding intramodel H-bonds Constraints relaxed by 0.4 angstroms and 20 degrees Models used: #0 5k1c_C.cif H-bonds (donor, acceptor, hydrogen, D..A dist, D-H..A dist): LYS 11.A N LYS 369.A O no hydrogen 2.863 N/A PHE 14.A N TYR 21.A O no hydrogen 3.122 N/A THR 16.A N GLY 19.A O no hydrogen 3.205 N/A GLY 19.A N THR 16.A O no hydrogen 2.834 N/A TYR 21.A N PHE 14.A O no hydrogen 2.832 N/A TYR 21.A OH GLU 18.A OE1 no hydrogen 2.643 N/A LYS 22.A N GLY 398.A O no hydrogen 3.302 N/A LYS 22.A NZ GLN 13.A OE1 no hydrogen 3.501 N/A LEU 23.A N THR 12.A O no hydrogen 3.035 N/A LEU 24.A N THR 396.A O no hydrogen 3.035 N/A SER 27.A N LEU 24.A O no hydrogen 3.055 N/A SER 27.A OG GLY 77.A O no hydrogen 3.237 N/A SER 27.A OG ARG 79.A O no hydrogen 2.853 N/A GLU 28.A N PRO 25.A O no hydrogen 3.056 N/A TYR 29.A N ILE 394.A O no hydrogen 2.970 N/A TYR 29.A OH ILE 74.A O no hydrogen 2.632 N/A SER 30.A OG ARG 31.A O no hydrogen 3.091 N/A ARG 31.A NE ASN 33.A OD1 no hydrogen 3.392 N/A ARG 31.A NE VAL 35.A O no hydrogen 3.281 N/A ARG 31.A NH2 VAL 35.A O no hydrogen 2.971 N/A ARG 34.A N ARG 31.A O no hydrogen 3.284 N/A VAL 35.A N ASN 33.A OD1 no hydrogen 2.705 N/A PHE 37.A N GLU 391.A O no hydrogen 3.213 N/A ARG 46.A N ASN 65.A OD1 no hydrogen 2.762 N/A ARG 46.A NE THR 376.A O no hydrogen 3.315 N/A SER 48.A N CYS 63.A O no hydrogen 3.022 N/A SER 48.A OG HIS 101.A O no hydrogen 3.270 N/A VAL 50.A N ARG 61.A O no hydrogen 3.243 N/A ASN 51.A ND2 ASP 60.A OD1 no hydrogen 3.181 N/A LEU 52.A N GLY 59.A O no hydrogen 2.843 N/A ARG 61.A N VAL 50.A O no hydrogen 2.907 N/A ARG 61.A NH1 ASN 58.A O no hydrogen 3.039 N/A ARG 61.A NH1 ASP 60.A O no hydrogen 2.773 N/A ARG 61.A NH2 ASN 58.A O no hydrogen 3.212 N/A LEU 62.A N TYR 73.A O no hydrogen 2.996 N/A CYS 63.A N SER 48.A O no hydrogen 2.986 N/A PHE 64.A N TYR 71.A O no hydrogen 3.389 N/A ASN 65.A ND2 PRO 44.A O no hydrogen 3.339 N/A VAL 66.A N GLU 69.A O no hydrogen 3.120 N/A GLU 69.A N VAL 66.A O no hydrogen 2.886 N/A TYR 71.A N PHE 64.A O no hydrogen 2.993 N/A TYR 71.A OH GLU 69.A OE2 no hydrogen 2.798 N/A TYR 73.A N LEU 62.A O no hydrogen 3.007 N/A TYR 73.A OH LEU 84.A O no hydrogen 2.710 N/A TYR 75.A N ASP 60.A O no hydrogen 3.085 N/A TYR 75.A OH THR 396.A OG1 no hydrogen 2.980 N/A LYS 76.A N TYR 29.A OH no hydrogen 3.420 N/A LYS 76.A NZ ASN 58.A OD1 no hydrogen 3.224 N/A ARG 79.A N LYS 76.A O no hydrogen 2.861 N/A ALA 81.A N HIS 26.A O no hydrogen 2.906 N/A ALA 82.A N TYR 29.A OH no hydrogen 3.095 N/A SER 85.A N ASP 83.A OD1 no hydrogen 2.731 N/A SER 85.A OG ASP 83.A OD1 no hydrogen 2.579 N/A SER 85.A OG ASP 83.A OD2 no hydrogen 3.490 N/A LYS 86.A N ASP 83.A O no hydrogen 3.476 N/A ILE 88.A N PHE 72.A O no hydrogen 3.056 N/A LYS 90.A NZ GLU 69.A OE1 no hydrogen 2.676 N/A LYS 90.A NZ TYR 71.A OH no hydrogen 2.963 N/A ARG 91.A NE ASP 89.A OD2 no hydrogen 2.894 N/A ARG 91.A NE LYS 90.A O no hydrogen 3.292 N/A TYR 93.A N ARG 68.A O no hydrogen 2.913 N/A THR 96.A OG1 SER 120.A OG no hydrogen 2.729 N/A GLN 97.A N SER 120.A OG no hydrogen 3.181 N/A THR 99.A OG1 VAL 149.A O no hydrogen 3.128 N/A HIS 101.A NE2 CYS 63.A O no hydrogen 3.304 N/A ASP 102.A N LEU 116.A O no hydrogen 3.085 N/A ASN 104.A N SER 114.A O no hydrogen 2.924 N/A ASN 104.A ND2 SER 158.A O no hydrogen 3.455 N/A LEU 106.A N ASN 104.A OD1 no hydrogen 2.850 N/A THR 107.A N ASN 104.A OD1 no hydrogen 2.822 N/A THR 107.A OG1 ASN 104.A OD1 no hydrogen 3.274 N/A THR 107.A OG1 THR 107.A O no hydrogen 2.487 N/A THR 109.A N SER 112.A O no hydrogen 2.824 N/A THR 109.A OG1 GLU 111.A OE1 no hydrogen 3.140 N/A SER 112.A OG ASP 128.A OD2 no hydrogen 2.511 N/A VAL 113.A N ASP 128.A OD1 no hydrogen 3.205 N/A VAL 113.A N ASP 128.A OD2 no hydrogen 3.131 N/A LEU 115.A N ILE 127.A O no hydrogen 3.149 N/A LEU 116.A N ASP 102.A O no hydrogen 3.000 N/A VAL 117.A N GLN 125.A O no hydrogen 3.007 N/A GLY 118.A N CYS 100.A O no hydrogen 2.965 N/A SER 120.A N GLN 97.A O no hydrogen 2.862 N/A SER 120.A OG THR 96.A OG1 no hydrogen 2.729 N/A SER 120.A OG GLN 97.A O no hydrogen 2.970 N/A GLY 122.A N PHE 119.A O no hydrogen 3.362 N/A VAL 124.A N PHE 138.A O no hydrogen 3.097 N/A GLN 125.A N VAL 117.A O no hydrogen 2.835 N/A ILE 127.A N LEU 115.A O no hydrogen 2.967 N/A ILE 130.A N ASP 128.A OD1 no hydrogen 3.453 N/A LYS 132.A N ASP 128.A O no hydrogen 2.790 N/A LYS 132.A NZ ILE 88.A O no hydrogen 3.129 N/A THR 134.A OG1 SER 135.A O no hydrogen 3.126 N/A SER 135.A OG THR 134.A O no hydrogen 2.594 N/A ASN 139.A ND2 GLY 122.A O no hydrogen 3.482 N/A ASN 139.A ND2 ASP 145.A O no hydrogen 2.958 N/A GLU 140.A N LEU 137.A O no hydrogen 3.318 N/A ARG 142.A N ASN 139.A O no hydrogen 2.962 N/A ARG 142.A NH1 ALA 121.A O no hydrogen 2.634 N/A ILE 144.A N ASN 139.A OD1 no hydrogen 3.020 N/A SER 147.A N ASP 145.A OD1 no hydrogen 3.181 N/A SER 147.A OG ASP 145.A OD1 no hydrogen 3.050 N/A SER 147.A OG SER 168.A OG no hydrogen 3.402 N/A VAL 149.A N PHE 119.A O no hydrogen 3.077 N/A THR 150.A N ALA 165.A O no hydrogen 2.547 N/A THR 150.A OG1 ALA 165.A O no hydrogen 3.063 N/A THR 150.A OG1 LEU 220.A O no hydrogen 2.727 N/A CYS 151.A N ALA 165.A O no hydrogen 3.368 N/A CYS 151.A SG PHE 223.A O no hydrogen 3.592 N/A LYS 153.A N LEU 163.A O no hydrogen 2.875 N/A TRP 154.A N ASP 102.A OD2 no hydrogen 3.057 N/A VAL 155.A N LEU 161.A O no hydrogen 3.334 N/A SER 158.A N VAL 155.A O no hydrogen 3.142 N/A SER 158.A OG LEU 161.A O no hydrogen 3.483 N/A SER 160.A N SER 158.A OG no hydrogen 2.644 N/A LEU 161.A N SER 158.A OG no hydrogen 2.642 N/A PHE 162.A N TYR 174.A O no hydrogen 2.952 N/A LEU 163.A N LYS 153.A O no hydrogen 2.833 N/A VAL 164.A N TYR 172.A O no hydrogen 3.118 N/A HIS 166.A N ASN 170.A O no hydrogen 2.975 N/A HIS 166.A ND1 SER 147.A O no hydrogen 2.784 N/A SER 167.A N ARG 148.A O no hydrogen 2.974 N/A SER 167.A OG ARG 148.A O no hydrogen 3.324 N/A SER 168.A N SER 147.A OG no hydrogen 3.220 N/A SER 168.A OG ASP 145.A OD2 no hydrogen 2.659 N/A SER 168.A OG SER 147.A OG no hydrogen 3.402 N/A GLY 169.A N HIS 166.A O no hydrogen 3.117 N/A ASN 170.A ND2 SER 168.A OG no hydrogen 3.405 N/A MET 171.A N TRP 213.A O no hydrogen 2.801 N/A TYR 172.A N VAL 164.A O no hydrogen 2.982 N/A TYR 172.A OH ASP 145.A OD2 no hydrogen 2.834 N/A LEU 173.A N LEU 211.A O no hydrogen 2.930 N/A TYR 174.A N PHE 162.A O no hydrogen 2.962 N/A VAL 176.A N SER 160.A O no hydrogen 2.731 N/A GLU 177.A N ASN 175.A OD1 no hydrogen 2.685 N/A HIS 178.A N ASN 175.A OD1 no hydrogen 3.370 N/A GLN 188.A N THR 200.A O no hydrogen 3.050 N/A LEU 190.A N VAL 198.A O no hydrogen 2.699 N/A LYS 191.A N VAL 198.A O no hydrogen 3.031 N/A GLY 193.A N PHE 196.A O no hydrogen 3.001 N/A ALA 197.A N THR 214.A O no hydrogen 2.893 N/A VAL 198.A N LYS 191.A O no hydrogen 3.056 N/A HIS 199.A N LYS 212.A O no hydrogen 3.015 N/A THR 200.A N GLN 188.A O no hydrogen 2.961 N/A CYS 201.A N LEU 210.A O no hydrogen 3.358 N/A CYS 201.A SG HIS 186.A O no hydrogen 3.836 N/A CYS 201.A SG ARG 207.A O no hydrogen 3.931 N/A LYS 202.A N HIS 186.A O no hydrogen 2.966 N/A SER 203.A OG SER 205.A O no hydrogen 3.338 N/A THR 206.A OG1 THR 206.A O no hydrogen 2.642 N/A ARG 207.A NH1 SER 205.A OG no hydrogen 3.411 N/A ASN 208.A N THR 179.A O no hydrogen 3.414 N/A LEU 210.A N ASN 208.A O no hydrogen 2.204 N/A LYS 212.A N HIS 199.A O no hydrogen 3.182 N/A TRP 213.A N MET 171.A O no hydrogen 2.658 N/A THR 214.A N ALA 197.A O no hydrogen 2.661 N/A THR 214.A OG1 ASN 170.A OD1 no hydrogen 2.701 N/A VAL 215.A N GLY 169.A O no hydrogen 3.149 N/A GLY 216.A N SER 195.A O no hydrogen 2.968 N/A GLU 217.A N ASP 238.A OD2 no hydrogen 3.004 N/A ASN 221.A N VAL 235.A O no hydrogen 3.019 N/A ASN 221.A ND2 GLN 237.A OE1 no hydrogen 3.243 N/A ALA 224.A N ALA 233.A O no hydrogen 2.736 N/A SER 226.A N PHE 231.A O no hydrogen 2.750 N/A SER 226.A OG ASP 228.A OD1 no hydrogen 2.823 N/A LYS 230.A N ASP 228.A OD1 no hydrogen 2.642 N/A LEU 232.A N PHE 244.A O no hydrogen 2.751 N/A ALA 233.A N ALA 224.A O no hydrogen 2.775 N/A CYS 234.A N ARG 242.A O no hydrogen 2.914 N/A VAL 235.A N GLU 222.A O no hydrogen 2.983 N/A SER 236.A N PHE 240.A O no hydrogen 3.299 N/A GLN 237.A N ALA 219.A O no hydrogen 2.856 N/A GLN 237.A NE2 GLU 279.A OE2 no hydrogen 2.840 N/A GLY 239.A N SER 236.A O no hydrogen 2.837 N/A PHE 240.A N ASP 238.A OD1 no hydrogen 3.312 N/A LEU 241.A N MET 255.A O no hydrogen 2.763 N/A ARG 242.A N CYS 234.A O no hydrogen 2.766 N/A ARG 242.A NH2 ASP 238.A OD1 no hydrogen 3.306 N/A ARG 242.A NH2 ASP 238.A OD2 no hydrogen 2.442 N/A VAL 243.A N GLY 253.A O no hydrogen 2.980 N/A PHE 244.A N LEU 232.A O no hydrogen 2.751 N/A ASN 245.A N GLU 250.A O no hydrogen 2.670 N/A PHE 246.A N LYS 230.A O no hydrogen 2.834 N/A SER 248.A N ASN 245.A OD1 no hydrogen 3.234 N/A VAL 249.A N PHE 246.A O no hydrogen 3.221 N/A GLU 250.A N ASN 245.A O no hydrogen 3.313 N/A HIS 252.A N VAL 243.A O no hydrogen 2.781 N/A GLY 253.A N VAL 243.A O no hydrogen 3.365 N/A MET 255.A N LEU 241.A O no hydrogen 2.977 N/A LYS 256.A NZ SER 257.A O no hydrogen 2.935 N/A LYS 256.A NZ SER 257.A OG no hydrogen 3.429 N/A SER 257.A N GLY 239.A O no hydrogen 3.066 N/A GLY 261.A N SER 257.A OG no hydrogen 3.292 N/A LEU 262.A N SER 236.A O no hydrogen 3.294 N/A LEU 263.A N GLY 277.A O no hydrogen 2.846 N/A CYS 264.A N GLY 277.A O no hydrogen 3.317 N/A CYS 264.A SG VAL 304.A O no hydrogen 3.742 N/A VAL 265.A N GLU 222.A OE1 no hydrogen 2.740 N/A CYS 266.A N VAL 275.A O no hydrogen 3.053 N/A TRP 267.A NE1 ALA 224.A O no hydrogen 2.944 N/A SER 268.A N TYR 273.A O no hydrogen 2.724 N/A SER 268.A OG ASP 270.A OD1 no hydrogen 3.094 N/A SER 268.A OG TYR 273.A O no hydrogen 2.757 N/A GLY 271.A N SER 268.A O no hydrogen 2.793 N/A LYS 272.A N ASP 270.A OD1 no hydrogen 2.773 N/A TYR 273.A N SER 268.A OG no hydrogen 2.535 N/A ILE 274.A N TRP 286.A O no hydrogen 2.875 N/A VAL 275.A N CYS 266.A O no hydrogen 3.135 N/A THR 276.A N THR 284.A O no hydrogen 2.955 N/A GLY 278.A N LEU 282.A O no hydrogen 3.354 N/A GLU 279.A N GLY 261.A O no hydrogen 3.109 N/A LEU 282.A N ASP 280.A OD1 no hydrogen 2.865 N/A VAL 283.A N GLY 297.A O no hydrogen 2.954 N/A THR 284.A N THR 276.A O no hydrogen 2.859 N/A VAL 285.A N ALA 295.A O no hydrogen 2.748 N/A TRP 286.A N ILE 274.A O no hydrogen 2.709 N/A SER 287.A N ARG 292.A O no hydrogen 2.818 N/A PHE 288.A N LYS 272.A O no hydrogen 3.057 N/A ASP 290.A N SER 287.A OG no hydrogen 3.343 N/A CYS 291.A N PHE 288.A O no hydrogen 3.352 N/A CYS 291.A SG HIS 252.A O no hydrogen 3.678 N/A CYS 291.A SG PHE 288.A O no hydrogen 3.503 N/A ARG 292.A N SER 287.A O no hydrogen 3.447 N/A ILE 294.A N VAL 285.A O no hydrogen 2.889 N/A ARG 296.A N PRO 360.A O no hydrogen 2.968 N/A ARG 296.A NH1 PRO 354.A O no hydrogen 2.982 N/A ARG 296.A NH2 PRO 354.A O no hydrogen 3.396 N/A GLY 297.A N VAL 283.A O no hydrogen 2.608 N/A HIS 300.A ND1 ASP 328.A OD2 no hydrogen 2.967 N/A HIS 300.A NE2 SER 324.A OG no hydrogen 2.903 N/A LYS 301.A N ASP 328.A OD2 no hydrogen 2.930 N/A VAL 304.A N GLY 278.A O no hydrogen 3.258 N/A SER 305.A N VAL 325.A O no hydrogen 2.940 N/A SER 305.A OG LEU 375.A O no hydrogen 3.288 N/A VAL 306.A N VAL 325.A O no hydrogen 3.233 N/A ALA 308.A N GLY 323.A O no hydrogen 2.956 N/A ASP 310.A N ARG 321.A O no hydrogen 2.830 N/A TYR 312.A N ASP 310.A OD1 no hydrogen 2.892 N/A THR 313.A N ASP 310.A O no hydrogen 3.184 N/A THR 313.A OG1 ASP 310.A OD2 no hydrogen 2.768 N/A THR 314.A OG1 ASP 310.A O no hydrogen 2.955 N/A SER 315.A N THR 319.A O no hydrogen 2.716 N/A SER 317.A OG GLU 338.A OE2 no hydrogen 3.067 N/A VAL 318.A N GLU 338.A OE2 no hydrogen 2.806 N/A THR 319.A OG1 LEU 336.A O no hydrogen 3.340 N/A TYR 320.A N LEU 336.A O no hydrogen 2.899 N/A TYR 320.A OH ASP 270.A OD2 no hydrogen 2.608 N/A ARG 321.A N THR 314.A OG1 no hydrogen 3.174 N/A ARG 321.A NE ASP 335.A OD1 no hydrogen 3.025 N/A ARG 321.A NH1 GLU 18.A OE1 no hydrogen 2.769 N/A ARG 321.A NH1 GLU 18.A OE2 no hydrogen 2.609 N/A ARG 321.A NH2 GLU 18.A OE2 no hydrogen 2.900 N/A ARG 321.A NH2 ASP 335.A OD1 no hydrogen 2.985 N/A ARG 321.A NH2 ASP 335.A OD2 no hydrogen 3.393 N/A PHE 322.A N TRP 334.A O no hydrogen 3.351 N/A GLY 323.A N ALA 308.A O no hydrogen 2.862 N/A SER 324.A N CYS 332.A O no hydrogen 2.802 N/A SER 324.A OG HIS 300.A NE2 no hydrogen 2.903 N/A VAL 325.A N VAL 306.A O no hydrogen 2.997 N/A GLY 326.A N GLN 330.A O no hydrogen 3.306 N/A GLN 327.A N TRP 303.A O no hydrogen 2.705 N/A THR 329.A N GLY 326.A O no hydrogen 3.245 N/A THR 329.A OG1 ASP 328.A O no hydrogen 2.643 N/A THR 329.A OG1 ALA 371.A O no hydrogen 3.038 N/A GLN 330.A N ASP 328.A OD1 no hydrogen 2.695 N/A LEU 331.A N LYS 368.A O no hydrogen 2.707 N/A CYS 332.A N SER 324.A O no hydrogen 2.963 N/A CYS 332.A SG HIS 300.A NE2 no hydrogen 3.420 N/A LEU 333.A N ILE 366.A O no hydrogen 3.405 N/A TRP 334.A N PHE 322.A O no hydrogen 2.687 N/A TRP 334.A NE1 SER 324.A OG no hydrogen 2.966 N/A LEU 336.A N TYR 320.A O no hydrogen 3.022 N/A THR 337.A OG1 ASP 339.A OD1 no hydrogen 2.610 N/A ILE 340.A N THR 337.A O no hydrogen 3.159 N/A LEU 341.A N THR 337.A O no hydrogen 3.212 N/A PHE 342.A N GLU 338.A O no hydrogen 2.841 N/A CYS 353.A SG LYS 256.A O no hydrogen 3.181 N/A ASP 358.A N ARG 355.A O no hydrogen 3.023 N/A VAL 359.A N ARG 355.A O no hydrogen 3.444 N/A LEU 362.A N ARG 296.A O no hydrogen 2.788 N/A LEU 365.A N LEU 333.A O no hydrogen 2.816 N/A CYS 367.A SG GLY 299.A O no hydrogen 3.641 N/A LYS 368.A N LEU 331.A O no hydrogen 2.962 N/A LYS 369.A NZ THR 329.A OG1 no hydrogen 3.040 N/A LYS 369.A NZ ALA 371.A O no hydrogen 2.879 N/A ILE 370.A N THR 329.A O no hydrogen 2.903 N/A LEU 375.A N GLY 326.A O no hydrogen 3.082 N/A THR 376.A N ALA 388.A O no hydrogen 2.652 N/A THR 376.A OG1 VAL 45.A O no hydrogen 2.874 N/A THR 376.A OG1 ALA 388.A O no hydrogen 3.121 N/A ILE 379.A N VAL 386.A O no hydrogen 3.028 N/A LEU 381.A N CYS 384.A O no hydrogen 3.192 N/A CYS 384.A N LEU 381.A O no hydrogen 3.262 N/A CYS 384.A SG TYR 75.A OH no hydrogen 3.633 N/A ILE 385.A N TRP 397.A O no hydrogen 3.058 N/A VAL 386.A N ILE 379.A O no hydrogen 2.933 N/A THR 387.A N CYS 395.A O no hydrogen 2.894 N/A ALA 388.A N VAL 377.A O no hydrogen 3.249 N/A GLN 390.A N ARG 374.A O no hydrogen 2.907 N/A GLN 390.A NE2 ASN 43.A O no hydrogen 3.333 N/A GLN 390.A NE2 GLN 390.A O no hydrogen 3.488 N/A GLY 392.A N CYS 389.A O no hydrogen 2.840 N/A ILE 394.A N TYR 29.A O no hydrogen 2.851 N/A CYS 395.A N THR 387.A O no hydrogen 2.699 N/A THR 396.A OG1 TYR 75.A OH no hydrogen 2.980 N/A TRP 397.A N ILE 385.A O no hydrogen 2.871 N/A TRP 397.A NE1 THR 387.A OG1 no hydrogen 2.821 N/A GLY 398.A N LYS 22.A O no hydrogen 2.860 N/A ARG 399.A N ASP 383.A O no hydrogen 2.935 N/A ARG 399.A NE LEU 381.A O no hydrogen 2.727 N/A ARG 399.A NH1 ASP 310.A OD2 no hydrogen 2.862 N/A ARG 399.A NH2 ASP 310.A OD1 no hydrogen 2.768 N/A ARG 399.A NH2 ASP 310.A OD2 no hydrogen 3.354 N/A ARG 399.A NH2 LEU 381.A O no hydrogen 2.990 N/A LYS 402.A N ARG 399.A O no hydrogen 2.876 N/A